Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucleP-body
BulkPerturb-seq DataSet_01_16

Description

Ensembl ID ENSG00000047188 Gene ID 64848 Accession 24721
Symbol YTHDC2 Alias CAHL;hYTHDC2 Full Name YTH N6-methyladenosine RNA binding protein C2
Status Confidence Length 81591 bases Strand Plus strand
Position 5 : 113513694 - 113595284 RNA binding domain DEAD , R3H , HA2 , YTH , OB_NTP_bind
Summary This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000423101 R3H PF01424 1.5e-10 1
ENSP00000423101 DEAD PF00270 1.5e-09 2
ENSP00000161863 R3H PF01424 3.8e-10 1
ENSP00000161863 DEAD PF00270 5.1e-09 2
ENSP00000161863 YTH PF04146 1.1e-41 3
ENSP00000161863 YTH PF04146 1.1e-41 4
ENSP00000161863 HA2 PF04408 1.7e-17 5
ENSP00000161863 OB_NTP_bind PF07717 7.9e-11 6
ENSP00000422916 R3H PF01424 5.8e-10 1
ENSP00000426644 R3H PF01424 2.6e-07 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36747642 YTHDC2 serves a distinct late role in spermatocytes during germ cell differentiation. S Alexis Bailey 2023-01-23 bioRxiv : the preprint server for biology
32956555 Downregulation of m6 A reader YTHDC2 promotes tumor progression and predicts poor prognosis in non-small cell lung cancer. Shulei Sun 2020-11-01 Thoracic cancer
32961012 m6A RNA methylation regulators could contribute to the occurrence of chronic obstructive pulmonary disease. Xinwei Huang 2020-11-01 Journal of cellular and molecular medicine
37152066 m6A modification on the fate of colorectal cancer: functions and mechanisms of cell proliferation and tumorigenesis. Xiaohan Jiang 2023-01-01 Frontiers in oncology
32850334 m6A Reader YTHDC2 Promotes Radiotherapy Resistance of Nasopharyngeal Carcinoma via Activating IGF1R/AKT/S6 Signaling Axis. Jun-Ju He 2020-01-01 Frontiers in oncology
37636387 YTHDC2 inhibits rat bone mesenchymal stem cells osteogenic differentiation by accelerating RUNX2 mRNA degradation via m6A methylation. Bo Ma 2023-08-01 Heliyon
36001654 RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis. Baomei Qian 2022-08-26 Science advances
29789545 Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism. Ying Yang 2018-06-01 Cell research
30891023 N6-Methyladenosine and Viral Infection. Wei Dang 2019-01-01 Frontiers in microbiology

Transcripts

Name Transcript ID bp Protein Translation ID
YTHDC2-202 ENST00000503857 2138 98aa ENSP00000426644
YTHDC2-201 ENST00000161863 6305 1430aa ENSP00000161863
YTHDC2-207 ENST00000515883 2629 739aa ENSP00000423101
YTHDC2-206 ENST00000514720 536 137aa ENSP00000422916
YTHDC2-203 ENST00000506333 784 No protein -
YTHDC2-205 ENST00000512600 6708 No protein -
YTHDC2-204 ENST00000507567 693 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
1106Body Weights and Measures4.18538902584586E-517903300
1288Body Weights and Measures4.38873780244098E-517903300
2568Body Weights and Measures7.37042521352649E-517903300
2683Body Weights and Measures6.92057409599212E-517903300
3992Triglycerides8.45932720099363E-517903299
22985Body Height6.8990000E-005-
23004Body Height7.2200000E-005-
23164Body Height7.4960000E-005-
23166Body Height8.7310000E-005-
29795Lipoprotein(a)8.9560000E-005-
31347Erythrocyte Indices1.3110000E-005-
31495Erythrocyte Count2.0630000E-006-
36319Platelet Function Tests9.6900000E-006-
36326Platelet Function Tests3.0200000E-006-
36571Platelet Function Tests2.2702400E-005-
39608Platelet Function Tests2.0620800E-005-
47047Platelet Function Tests2.6103000E-005-
47049Platelet Function Tests4.2897000E-005-
47765Language Tests2.3133000E-005-
47782Language Tests3.8634000E-005-
55250Erythrocyte Indices4.4560000E-005-
59392Arterial Pressure2.8110000E-006-
59400Arterial Pressure5.8670000E-006-
73085Death, Sudden, Cardiac4E-821658281
90060Anemia, Sickle Cell8E-621326311
90061Fetal Hemoglobin8E-621326311
102858Sleep7E-627126917
105815Alzheimer Disease9E-726830138
105816Age of Onset9E-726830138

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000047188homo_sapiensENSP0000026848232.192319.0709homo_sapiensENSP0000016186327.622416.3636
ENSG00000047188homo_sapiensENSP0000025163636.230823.74homo_sapiensENSP0000016186334.685322.7273
ENSG00000047188homo_sapiensENSP0000033190738.757724.0595homo_sapiensENSP0000016186330.97919.2308
ENSG00000047188homo_sapiensENSP0000035652036.614224.9606homo_sapiensENSP0000016186332.517522.1678
ENSG00000047188homo_sapiensENSP0000028469044.952924.2261homo_sapiensENSP0000016186323.356612.5874
ENSG00000047188homo_sapiensENSP0000022529646.110326.7327homo_sapiensENSP0000016186322.797213.2168
ENSG00000047188homo_sapiensENSP0000024781525.02312.5115homo_sapiensENSP0000016186319.0219.51049
ENSG00000047188homo_sapiensENSP0000038462144.630425.2441homo_sapiensENSP0000016186322.377612.6573
ENSG00000047188homo_sapiensENSP0000025201150.355630.1565homo_sapiensENSP0000016186324.755214.8252
ENSG00000047188homo_sapiensENSP0000031113534.74520.8297homo_sapiensENSP0000016186328.111916.8531
ENSG00000047188homo_sapiensENSP0000040511136.724423.8095homo_sapiensENSP0000016186335.594423.0769
ENSG00000047188homo_sapiensENSP0000036562536.311222.3823homo_sapiensENSP0000016186326.433616.2937
ENSG00000047188homo_sapiensENSP0000041707847.321431.0516homo_sapiensENSP0000016186333.356621.8881
ENSG00000047188homo_sapiensENSP0000025124147.368425.6739homo_sapiensENSP0000016186325.804213.986
ENSG00000047188homo_sapiensENSP0000033674147.169829.434homo_sapiensENSP0000016186326.223816.3636
ENSG00000047188homo_sapiensENSP0000040562038.107223.6181homo_sapiensENSP0000016186331.818219.7203
ENSG00000047188homo_sapiensENSP0000026241533.032818.8525homo_sapiensENSP0000016186328.181816.0839
ENSG00000047188homo_sapiensENSP0000038730331.620818.4515homo_sapiensENSP0000016186330.559417.8322

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000047188homo_sapiensENSP0000016186399.440698.6713nomascus_leucogenysENSNLEP0000001422199.440698.6713
ENSG00000047188homo_sapiensENSP0000016186399.860199.6504pan_paniscusENSPPAP0000000448099.860199.6504
ENSG00000047188homo_sapiensENSP0000016186398.741397.9021pongo_abeliiENSPPYP0000003831198.123797.2898
ENSG00000047188homo_sapiensENSP0000016186399.790299.5804pan_troglodytesENSPTRP0000002933799.790299.5804
ENSG00000047188homo_sapiensENSP0000016186399.720399.4406gorilla_gorillaENSGGOP0000001964099.720399.4406
ENSG00000047188homo_sapiensENSP0000016186384.475572.0979ornithorhynchus_anatinusENSOANP0000004431778.492566.9916
ENSG00000047188homo_sapiensENSP0000016186398.601496.4336sarcophilus_harrisiiENSSHAP0000000353197.984795.8304
ENSG00000047188homo_sapiensENSP0000016186373.566471.4685notamacropus_eugeniiENSMEUP0000000404173.566471.4685
ENSG00000047188homo_sapiensENSP0000016186376.433674.7552choloepus_hoffmanniENSCHOP0000001182080.308678.5452
ENSG00000047188homo_sapiensENSP0000016186397.202894.5455dasypus_novemcinctusENSDNOP0000000948897.134994.4794
ENSG00000047188homo_sapiensENSP0000016186382.377680.2098erinaceus_europaeusENSEEUP0000000788683.486981.2899
ENSG00000047188homo_sapiensENSP0000016186374.055972.3077echinops_telfairiENSETEP0000001109775.159773.3854
ENSG00000047188homo_sapiensENSP0000016186399.02197.8322callithrix_jacchusENSCJAP0000008316199.02197.8322
ENSG00000047188homo_sapiensENSP0000016186399.790299.2308cercocebus_atysENSCATP0000001539799.790299.2308
ENSG00000047188homo_sapiensENSP0000016186395.384694.8951macaca_fascicularisENSMFAP0000005861199.780599.2685
ENSG00000047188homo_sapiensENSP0000016186399.790299.2308macaca_mulattaENSMMUP0000000183499.790299.2308
ENSG00000047188homo_sapiensENSP0000016186399.790299.3007macaca_nemestrinaENSMNEP0000003551399.790299.3007
ENSG00000047188homo_sapiensENSP0000016186399.720399.0909papio_anubisENSPANP0000004961099.720399.0909
ENSG00000047188homo_sapiensENSP0000016186399.720399.3007mandrillus_leucophaeusENSMLEP0000003824899.720399.3007
ENSG00000047188homo_sapiensENSP0000016186373.076971.049tursiops_truncatusENSTTRP0000000292474.803172.7273
ENSG00000047188homo_sapiensENSP0000016186398.95197.2727vulpes_vulpesENSVVUP0000000028999.020397.3408
ENSG00000047188homo_sapiensENSP0000016186398.671396.993mus_spretusMGP_SPRETEiJ_P004859197.850296.1859
ENSG00000047188homo_sapiensENSP0000016186398.811297.5524equus_asinusENSEASP0000502215398.535697.2803
ENSG00000047188homo_sapiensENSP0000016186398.391696.7832capra_hircusENSCHIP0000003284798.460596.8509
ENSG00000047188homo_sapiensENSP0000016186387.902186.6434loxodonta_africanaENSLAFP0000000294998.665697.2527
ENSG00000047188homo_sapiensENSP0000016186398.601497.0629panthera_leoENSPLOP0000000102798.739597.1989
ENSG00000047188homo_sapiensENSP0000016186398.531596.9231ailuropoda_melanoleucaENSAMEP0000000697298.600496.9909
ENSG00000047188homo_sapiensENSP0000016186396.363694.4755bos_indicus_hybridENSBIXP0000503832396.97495.0739
ENSG00000047188homo_sapiensENSP0000016186394.405692.9371oryctolagus_cuniculusENSOCUP0000001041498.756497.2202
ENSG00000047188homo_sapiensENSP0000016186396.923195.6643equus_caballusENSECAP0000001827898.507597.2281
ENSG00000047188homo_sapiensENSP0000016186398.95197.3427canis_lupus_familiarisENSCAFP0084501439499.020397.4108
ENSG00000047188homo_sapiensENSP0000016186398.531597.1329panthera_pardusENSPPRP0000000604898.669597.2689
ENSG00000047188homo_sapiensENSP0000016186397.97296.6434marmota_marmota_marmotaENSMMMP0000000737698.384897.0506
ENSG00000047188homo_sapiensENSP0000016186398.321796.2937balaenoptera_musculusENSBMSP0001001747098.321796.2937
ENSG00000047188homo_sapiensENSP0000016186398.391696.7832cavia_porcellusENSCPOP0000002326497.844296.2448
ENSG00000047188homo_sapiensENSP0000016186398.601497.1329felis_catusENSFCAP0000001853498.739597.2689
ENSG00000047188homo_sapiensENSP0000016186375.244874.3357ursus_americanusENSUAMP0000000413998.897197.7022
ENSG00000047188homo_sapiensENSP0000016186398.531596.3636monodelphis_domesticaENSMODP0000001955897.373995.2315
ENSG00000047188homo_sapiensENSP0000016186398.391696.7832bison_bison_bisonENSBBBP0000000147198.460596.8509
ENSG00000047188homo_sapiensENSP0000016186397.692394.965monodon_monocerosENSMMNP0001500128897.760795.0315
ENSG00000047188homo_sapiensENSP0000016186398.671397.4126sus_scrofaENSSSCP0000004890498.878897.6174
ENSG00000047188homo_sapiensENSP0000016186399.160897.8322microcebus_murinusENSMICP0000002526598.677897.3556
ENSG00000047188homo_sapiensENSP0000016186398.251796.1538octodon_degusENSODEP0000001045298.046195.9525
ENSG00000047188homo_sapiensENSP0000016186395.524593.2168jaculus_jaculusENSJJAP0000001591395.591393.282
ENSG00000047188homo_sapiensENSP0000016186398.391696.7832ovis_aries_rambouilletENSOARP0002002174898.460596.8509
ENSG00000047188homo_sapiensENSP0000016186395.174893.7063ursus_maritimusENSUMAP0000003315198.909997.3837
ENSG00000047188homo_sapiensENSP0000016186373.00771.6084ochotona_princepsENSOPRP0000000043473.263271.8596
ENSG00000047188homo_sapiensENSP0000016186397.692394.965delphinapterus_leucasENSDLEP0000002779597.760795.0315
ENSG00000047188homo_sapiensENSP0000016186398.04295.9441physeter_catodonENSPCTP0000500094698.04295.9441
ENSG00000047188homo_sapiensENSP0000016186398.671396.993mus_caroliMGP_CAROLIEiJ_P004666397.647195.9862
ENSG00000047188homo_sapiensENSP0000016186398.741396.993mus_musculusENSMUSP0000004834097.716395.9862
ENSG00000047188homo_sapiensENSP0000016186392.447690dipodomys_ordiiENSDORP0000000661694.903192.3905
ENSG00000047188homo_sapiensENSP0000016186394.895193.0769mustela_putorius_furoENSMPUP0000000075297.978396.1011
ENSG00000047188homo_sapiensENSP0000016186396.503595.2448aotus_nancymaaeENSANAP0000000845298.150896.8706
ENSG00000047188homo_sapiensENSP0000016186399.370698.5315saimiri_boliviensis_boliviensisENSSBOP0000001417999.370698.5315
ENSG00000047188homo_sapiensENSP0000016186389.720387.3427vicugna_pacosENSVPAP0000000699290.415888.0197
ENSG00000047188homo_sapiensENSP0000016186399.580499.1608chlorocebus_sabaeusENSCSAP0000001100699.580499.1608
ENSG00000047188homo_sapiensENSP0000016186370.97969.3007tupaia_belangeriENSTBEP0000000597374.413572.654
ENSG00000047188homo_sapiensENSP0000016186398.601496.993mesocricetus_auratusENSMAUP0000001730897.713196.1192
ENSG00000047188homo_sapiensENSP0000016186397.762295.1748phocoena_sinusENSPSNP0000000077897.830795.2414
ENSG00000047188homo_sapiensENSP0000016186398.811297.2727camelus_dromedariusENSCDRP0000500884698.880397.3408
ENSG00000047188homo_sapiensENSP0000016186395.454594.1259carlito_syrichtaENSTSYP0000000885997.849596.4875
ENSG00000047188homo_sapiensENSP0000016186394.405692.9371panthera_tigris_altaicaENSPTIP0000002636394.405692.9371
ENSG00000047188homo_sapiensENSP0000016186398.671397.1329rattus_norvegicusENSRNOP0000007822598.396196.8619
ENSG00000047188homo_sapiensENSP0000016186399.02197.6923prolemur_simusENSPSMP0000003678598.813797.4878
ENSG00000047188homo_sapiensENSP0000016186398.741397.0629microtus_ochrogasterENSMOCP0000001149598.397296.7247
ENSG00000047188homo_sapiensENSP0000016186379.300777.972sorex_araneusENSSARP0000000087784.880283.4581
ENSG00000047188homo_sapiensENSP0000016186398.741397.2028peromyscus_maniculatus_bairdiiENSPEMP0000001996097.245295.73
ENSG00000047188homo_sapiensENSP0000016186398.391696.7832bos_mutusENSBMUP0000000346498.460596.8509
ENSG00000047188homo_sapiensENSP0000016186398.741396.9231mus_spicilegusENSMSIP0000002883797.851796.0499
ENSG00000047188homo_sapiensENSP0000016186398.671397.0629cricetulus_griseus_chok1gshdENSCGRP0000102296098.464896.8597
ENSG00000047188homo_sapiensENSP0000016186391.538590.0699pteropus_vampyrusENSPVAP0000001165391.538590.0699
ENSG00000047188homo_sapiensENSP0000016186398.181896.1538myotis_lucifugusENSMLUP0000000559097.567895.5525
ENSG00000047188homo_sapiensENSP0000016186394.335792.0979vombatus_ursinusENSVURP0001000827398.683396.3424
ENSG00000047188homo_sapiensENSP0000016186398.811297.3427rhinolophus_ferrumequinumENSRFEP0001002193998.949697.479
ENSG00000047188homo_sapiensENSP0000016186398.601496.9231neovison_visonENSNVIP0000002999998.670496.9909
ENSG00000047188homo_sapiensENSP0000016186398.391696.7832bos_taurusENSBTAP0000001874598.460596.8509
ENSG00000047188homo_sapiensENSP0000016186397.622495.6643heterocephalus_glaber_femaleENSHGLP0000002672997.350195.3975
ENSG00000047188homo_sapiensENSP0000016186397.692396.8531rhinopithecus_bietiENSRBIP0000003304798.51997.6728
ENSG00000047188homo_sapiensENSP0000016186397.412695.8741canis_lupus_dingoENSCAFP0002000470397.82396.2781
ENSG00000047188homo_sapiensENSP0000016186398.95197.7622sciurus_vulgarisENSSVLP0000501309498.606397.4216
ENSG00000047188homo_sapiensENSP0000016186398.321795.7343phascolarctos_cinereusENSPCIP0000000522498.666796.0702
ENSG00000047188homo_sapiensENSP0000016186376.083974.4755procavia_capensisENSPCAP0000000736376.944875.3182
ENSG00000047188homo_sapiensENSP0000016186397.97296.2937nannospalax_galiliENSNGAP0000001732998.17896.4961
ENSG00000047188homo_sapiensENSP0000016186398.391696.7832bos_grunniensENSBGRP0000001915998.460596.8509
ENSG00000047188homo_sapiensENSP0000016186398.321796.2937chinchilla_lanigeraENSCLAP0000002055497.435995.4262
ENSG00000047188homo_sapiensENSP0000016186398.531596.7832cervus_hanglu_yarkandensisENSCHYP0000004077498.600496.8509
ENSG00000047188homo_sapiensENSP0000016186398.461596.7832catagonus_wagneriENSCWAP0000000143998.668596.9867
ENSG00000047188homo_sapiensENSP0000016186397.272795.8741ictidomys_tridecemlineatusENSSTOP0000001187697.069195.6734
ENSG00000047188homo_sapiensENSP0000016186399.090997.7622otolemur_garnettiiENSOGAP0000000144198.676997.3538
ENSG00000047188homo_sapiensENSP0000016186399.440698.3916cebus_imitatorENSCCAP0000003960399.371198.3229
ENSG00000047188homo_sapiensENSP0000016186398.601496.7832moschus_moschiferusENSMMSP0000000779198.670496.8509
ENSG00000047188homo_sapiensENSP0000016186399.720399.1608rhinopithecus_roxellanaENSRROP0000003156499.720399.1608
ENSG00000047188homo_sapiensENSP0000016186398.741396.993mus_pahariMGP_PahariEiJ_P003925297.783996.0526
ENSG00000047188homo_sapiensENSP0000016186391.468588.6014propithecus_coquereliENSPCOP0000001198196.817293.7824
ENSG00000047188homo_sapiensENSP0000016186335.734321.5385drosophila_melanogasterFBpp030882752.356631.5574
ENSG00000047188homo_sapiensENSP0000016186316.01411.958ciona_intestinalisENSCINP0000001157465.804649.1379
ENSG00000047188homo_sapiensENSP0000016186376.853161.7483petromyzon_marinusENSPMAP0000000353177.722862.447
ENSG00000047188homo_sapiensENSP0000016186362.657346.993eptatretus_burgeriENSEBUP0000002336464.367848.2759
ENSG00000047188homo_sapiensENSP0000016186324.685317.6923eptatretus_burgeriENSEBUP0000000631862.923445.098
ENSG00000047188homo_sapiensENSP0000016186389.860181.958callorhinchus_miliiENSCMIP0000004214290.365782.4191
ENSG00000047188homo_sapiensENSP0000016186392.797285.6643latimeria_chalumnaeENSLACP0000001247392.862185.7243
ENSG00000047188homo_sapiensENSP0000016186386.153876.1538lepisosteus_oculatusENSLOCP0000001096286.33576.3139
ENSG00000047188homo_sapiensENSP0000016186375.944161.8881danio_rerioENSDARP0000013219676.749162.5442
ENSG00000047188homo_sapiensENSP0000016186382.657370carassius_auratusENSCARP0000005416485.776572.6415
ENSG00000047188homo_sapiensENSP0000016186385.174872.7273astyanax_mexicanusENSAMXP0000000925585.895673.3427
ENSG00000047188homo_sapiensENSP0000016186382.937171.7483ictalurus_punctatusENSIPUP0000002900581.793170.7586
ENSG00000047188homo_sapiensENSP0000016186386.573475.1748esox_luciusENSELUP0000003651485.320574.0868
ENSG00000047188homo_sapiensENSP0000016186382.167870.3496electrophorus_electricusENSEEEP0000003603883.038971.0954
ENSG00000047188homo_sapiensENSP0000016186386.713375.9441oncorhynchus_kisutchENSOKIP0000507937985.106474.5367
ENSG00000047188homo_sapiensENSP0000016186386.783276.1538oncorhynchus_mykissENSOMYP0000009045486.120875.5725
ENSG00000047188homo_sapiensENSP0000016186336.853130.3496salmo_salarENSSSAP0000008498075.393462.0887
ENSG00000047188homo_sapiensENSP0000016186386.923176.2937salmo_salarENSSSAP0000014945785.724175.2414
ENSG00000047188homo_sapiensENSP0000016186386.923176.3636salmo_truttaENSSTUP0000005029885.724175.3103
ENSG00000047188homo_sapiensENSP0000016186337.412631.6084salmo_truttaENSSTUP0000000848376.537964.6638
ENSG00000047188homo_sapiensENSP0000016186357.832245.4545gadus_morhuaENSGMOP0000004648371.109255.8899
ENSG00000047188homo_sapiensENSP0000016186375.104960.6993fundulus_heteroclitusENSFHEP0000002639474.171359.9448
ENSG00000047188homo_sapiensENSP0000016186375.874160.8392poecilia_reticulataENSPREP0000001794576.516261.354
ENSG00000047188homo_sapiensENSP0000016186375.244860.7692xiphophorus_maculatusENSXMAP0000003533176.967162.1602
ENSG00000047188homo_sapiensENSP0000016186364.545550.4895oryzias_latipesENSORLP0000002381571.884756.2305
ENSG00000047188homo_sapiensENSP0000016186376.713363.4266cyclopterus_lumpusENSCLMP0000504675177.967364.4634
ENSG00000047188homo_sapiensENSP0000016186374.195860.9091oreochromis_niloticusENSONIP0000005481278.014764.0441
ENSG00000047188homo_sapiensENSP0000016186366.503554.4056haplochromis_burtoniENSHBUP0000002544578.790464.4573
ENSG00000047188homo_sapiensENSP0000016186374.265761.6084astatotilapia_callipteraENSACLP0000002816277.859264.5894
ENSG00000047188homo_sapiensENSP0000016186376.573463.5664sparus_aurataENSSAUP0001002803878.270264.975
ENSG00000047188homo_sapiensENSP0000016186376.853163.5664lates_calcariferENSLCAP0001004649081.047267.0354
ENSG00000047188homo_sapiensENSP0000016186389.510581.049xenopus_tropicalisENSXETP0000004651687.851879.547
ENSG00000047188homo_sapiensENSP0000016186396.713392.5175chrysemys_picta_belliiENSCPBP0000001915196.78192.5822
ENSG00000047188homo_sapiensENSP0000016186348.321745.9441sphenodon_punctatusENSSPUP0000002073894.917690.2473
ENSG00000047188homo_sapiensENSP0000016186343.286741.1888sphenodon_punctatusENSSPUP0000002076896.870192.1753
ENSG00000047188homo_sapiensENSP0000016186395.314791.5385crocodylus_porosusENSCPRP0000500925695.985992.1831
ENSG00000047188homo_sapiensENSP0000016186357.832254.7552laticauda_laticaudataENSLLTP0000000488394.191389.18
ENSG00000047188homo_sapiensENSP0000016186344.405640.8392notechis_scutatusENSNSUP0000001806987.225380.2198
ENSG00000047188homo_sapiensENSP0000016186394.755290.2797pseudonaja_textilisENSPTXP0000000159894.228189.7775
ENSG00000047188homo_sapiensENSP0000016186379.860173.007anas_platyrhynchos_platyrhynchosENSAPLP0000002292289.568681.8824
ENSG00000047188homo_sapiensENSP0000016186389.090980.2098gallus_gallusENSGALP0001001126488.533779.7081
ENSG00000047188homo_sapiensENSP0000016186347.97242.8671meleagris_gallopavoENSMGAP0000000672685.536276.4339
ENSG00000047188homo_sapiensENSP0000016186387.552478.8811serinus_canariaENSSCAP0000002044988.920580.1136
ENSG00000047188homo_sapiensENSP0000016186386.433678.4615serinus_canariaENSSCAP0000000638891.016282.6215
ENSG00000047188homo_sapiensENSP0000016186389.650481.3986parus_majorENSPMJP0000001690389.901881.6269
ENSG00000047188homo_sapiensENSP0000016186390.069981.5385parus_majorENSPMJP0000000690390.640482.0549
ENSG00000047188homo_sapiensENSP0000016186392.237888.4615anolis_carolinensisENSACAP0000000763592.496588.7097
ENSG00000047188homo_sapiensENSP0000016186372.377658.8112neolamprologus_brichardiENSNBRP0000000098975.547461.3869
ENSG00000047188homo_sapiensENSP0000016186389.370685.1748naja_najaENSNNAP0000000309395.658791.1677
ENSG00000047188homo_sapiensENSP0000016186395.03591.2587podarcis_muralisENSPMRP0000001815091.576887.938
ENSG00000047188homo_sapiensENSP0000016186385.454577.4825geospiza_fortisENSGFOP0000000343790.787582.318
ENSG00000047188homo_sapiensENSP0000016186387.482579.2308geospiza_fortisENSGFOP0000000981390.981882.4
ENSG00000047188homo_sapiensENSP0000016186379.720370.5594taeniopygia_guttataENSTGUP0000002342385.972876.0935
ENSG00000047188homo_sapiensENSP0000016186370.069961.6783taeniopygia_guttataENSTGUP0000001460180.481970.8434
ENSG00000047188homo_sapiensENSP0000016186388.671379.9301taeniopygia_guttataENSTGUP0000000388489.421780.6065
ENSG00000047188homo_sapiensENSP0000016186362.237855.2448taeniopygia_guttataENSTGUP0000003007985.08675.5258
ENSG00000047188homo_sapiensENSP0000016186378.95169.7203erpetoichthys_calabaricusENSECRP0000000819785.790375.7599
ENSG00000047188homo_sapiensENSP0000016186376.293761.6084kryptolebias_marmoratusENSKMAP0000002154078.095963.0637
ENSG00000047188homo_sapiensENSP0000016186394.825290.7692salvator_merianaeENSSMRP0000000326993.195989.2096
ENSG00000047188homo_sapiensENSP0000016186369.930155.3846oryzias_javanicusENSOJAP0000001214972.727357.6
ENSG00000047188homo_sapiensENSP0000016186373.846261.6783amphilophus_citrinellusENSACIP0000001649079.63866.5158
ENSG00000047188homo_sapiensENSP0000016186376.223863.1469dicentrarchus_labraxENSDLAP0000505566078.248464.8241
ENSG00000047188homo_sapiensENSP0000016186375.804262.7972amphiprion_perculaENSAPEP0000002097177.26364.0057
ENSG00000047188homo_sapiensENSP0000016186393.076989.4406pelodiscus_sinensisENSPSIP0000001680597.366593.5625
ENSG00000047188homo_sapiensENSP0000016186393.146989.3706gopherus_evgoodeiENSGEVP0000500090697.439793.4894
ENSG00000047188homo_sapiensENSP0000016186396.643492.6573chelonoidis_abingdoniiENSCABP0000001237996.71192.7222
ENSG00000047188homo_sapiensENSP0000016186377.832264.5455seriola_dumeriliENSSDUP0000002973577.886664.5906
ENSG00000047188homo_sapiensENSP0000016186377.272763.7762cottoperca_gobioENSCGOP0000003326378.98565.1894
ENSG00000047188homo_sapiensENSP0000016186392.237887.7622struthio_camelus_australisENSSCUP0000002539596.488791.8069
ENSG00000047188homo_sapiensENSP0000016186392.377684.7552anser_brachyrhynchusENSABRP0000000370492.766985.1124
ENSG00000047188homo_sapiensENSP0000016186344.335737.0629gasterosteus_aculeatusENSGACP0000002455082.552169.0104
ENSG00000047188homo_sapiensENSP0000016186358.881143.7063cynoglossus_semilaevisENSCSEP0000002803069.07351.2715
ENSG00000047188homo_sapiensENSP0000016186351.818242.3077poecilia_formosaENSPFOP0000000421478.829864.3617
ENSG00000047188homo_sapiensENSP0000016186375.734361.3287myripristis_murdjanENSMMDP0000502890976.645462.0665
ENSG00000047188homo_sapiensENSP0000016186375.734362.028sander_luciopercaENSSLUP0000004077777.136763.1766
ENSG00000047188homo_sapiensENSP0000016186393.916186.5734strigops_habroptilaENSSHBP0000500435194.047686.6947
ENSG00000047188homo_sapiensENSP0000016186368.671357.6224amphiprion_ocellarisENSAOCP0000001382677.874765.345
ENSG00000047188homo_sapiensENSP0000016186396.573492.5175terrapene_carolina_triunguisENSTMTP0000003066096.64192.5822
ENSG00000047188homo_sapiensENSP0000016186353.496544.8252hucho_huchoENSHHUP0000006732877.116964.6169
ENSG00000047188homo_sapiensENSP0000016186386.853175.6643hucho_huchoENSHHUP0000001196185.832874.7754
ENSG00000047188homo_sapiensENSP0000016186374.125960.0699betta_splendensENSBSLP0000000807176.149461.7098
ENSG00000047188homo_sapiensENSP0000016186384.96574.0559pygocentrus_nattereriENSPNAP0000000360485.926574.8939
ENSG00000047188homo_sapiensENSP0000016186375.664361.958anabas_testudineusENSATEP0000001575577.285763.2857
ENSG00000047188homo_sapiensENSP0000016186377.692364.5455seriola_lalandi_dorsalisENSSLDP0000002966779.928166.4029
ENSG00000047188homo_sapiensENSP0000016186375.944161.6084labrus_bergyltaENSLBEP0000003743862.593750.7781
ENSG00000047188homo_sapiensENSP0000016186372.587458.5315pundamilia_nyerereiENSPNYP0000000919976.04461.3187
ENSG00000047188homo_sapiensENSP0000016186376.783263.8462mastacembelus_armatusENSMAMP0000002856278.038464.8898
ENSG00000047188homo_sapiensENSP0000016186375.454562.8671stegastes_partitusENSSPAP0000001978276.961564.1227
ENSG00000047188homo_sapiensENSP0000016186386.643475.8741oncorhynchus_tshawytschaENSOTSP0000502073685.271974.6731
ENSG00000047188homo_sapiensENSP0000016186335.804229.3706oncorhynchus_tshawytschaENSOTSP0000502777678.167964.1221
ENSG00000047188homo_sapiensENSP0000016186386.643475.8741oncorhynchus_tshawytschaENSOTSP0000507244685.271974.6731
ENSG00000047188homo_sapiensENSP0000016186354.96545.4545acanthochromis_polyacanthusENSAPOP0000001087975.722562.6204
ENSG00000047188homo_sapiensENSP0000016186385.594478.7413aquila_chrysaetos_chrysaetosENSACCP0002002293192.030184.6617
ENSG00000047188homo_sapiensENSP0000016186393.076985.9441aquila_chrysaetos_chrysaetosENSACCP0002002274592.946985.824
ENSG00000047188homo_sapiensENSP0000016186374.265759.4406nothobranchius_furzeriENSNFUP0001500328876.238361.0194
ENSG00000047188homo_sapiensENSP0000016186374.475559.3706cyprinodon_variegatusENSCVAP0000001809376.784461.2112
ENSG00000047188homo_sapiensENSP0000016186380.769267.8322denticeps_clupeoidesENSDCDP0000004979082.206469.0391
ENSG00000047188homo_sapiensENSP0000016186375.664361.8182larimichthys_croceaENSLCRP0000502791376.0962.166
ENSG00000047188homo_sapiensENSP0000016186372.867158.1119takifugu_rubripesENSTRUP0000007934975.83760.4804
ENSG00000047188homo_sapiensENSP0000016186383.356675.5245ficedula_albicollisENSFALP0000000273391.201282.632
ENSG00000047188homo_sapiensENSP0000016186387.062979.1608ficedula_albicollisENSFALP0000000004291.208882.9304
ENSG00000047188homo_sapiensENSP0000016186369.650455.1748hippocampus_comesENSHCOP0000002471175.169859.5472
ENSG00000047188homo_sapiensENSP0000016186382.657370.2797cyprinus_carpio_carpioENSCCRP0000014601980.027168.0433
ENSG00000047188homo_sapiensENSP0000016186387.902178.6713coturnix_japonicaENSCJPP0000501116187.656978.4519
ENSG00000047188homo_sapiensENSP0000016186375.594460.8392poecilia_latipinnaENSPLAP0000000555677.713962.5449
ENSG00000047188homo_sapiensENSP0000016186376.99365.9441sinocyclocheilus_grahamiENSSGRP0000000160584.562272.427
ENSG00000047188homo_sapiensENSP0000016186375.174861.5385maylandia_zebraENSMZEP0000501222777.505463.4463
ENSG00000047188homo_sapiensENSP0000016186368.95154.965tetraodon_nigroviridisENSTNIP0000000630674.135359.0977
ENSG00000047188homo_sapiensENSP0000016186382.447669.3706paramormyrops_kingsleyaeENSPKIP0000003812282.332469.2737
ENSG00000047188homo_sapiensENSP0000016186378.601466.0839scleropages_formosusENSSFOP0001500559980.11467.3557
ENSG00000047188homo_sapiensENSP0000016186389.720381.8881leptobrachium_leishanenseENSLLEP0000002230689.908982.0603
ENSG00000047188homo_sapiensENSP0000016186365.104951.5385scophthalmus_maximusENSSMAP0000003556573.771858.3994
ENSG00000047188homo_sapiensENSP0000016186369.860155.3846oryzias_melastigmaENSOMEP0000001280673.240558.0645

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding2HDA,IBAHomo_sapiens(9606)Function
GO:0004386enables helicase activity1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005622is_active_in intracellular anatomical structure1IBAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0007286involved_in spermatid development1ISSHomo_sapiens(9606)Process
GO:0008186enables ATP-dependent activity, acting on RNA1IDAHomo_sapiens(9606)Function
GO:0016887enables ATP hydrolysis activity1IEAHomo_sapiens(9606)Function
GO:0034458enables 3-5 RNA helicase activity1IDAHomo_sapiens(9606)Function
GO:0034612involved_in response to tumor necrosis factor1IDAHomo_sapiens(9606)Process
GO:0035770located_in ribonucleoprotein granule1ISSHomo_sapiens(9606)Component
GO:0044829involved_in positive regulation by host of viral genome replication1IMPHomo_sapiens(9606)Process
GO:0048471located_in perinuclear region of cytoplasm1IEAHomo_sapiens(9606)Component
GO:0048599involved_in oocyte development1ISSHomo_sapiens(9606)Process
GO:0051321involved_in meiotic cell cycle1IEAHomo_sapiens(9606)Process
GO:0051729involved_in germline cell cycle switching, mitotic to meiotic cell cycle1ISSHomo_sapiens(9606)Process
GO:0070063enables RNA polymerase binding1IPIHomo_sapiens(9606)Function
GO:0070555involved_in response to interleukin-11IDAHomo_sapiens(9606)Process
GO:1990247enables N6-methyladenosine-containing RNA binding1IDAHomo_sapiens(9606)Function

Expression