Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs tRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_223 DataSet_01_95

Description

Ensembl ID ENSG00000037474 Gene ID 54888 Accession 25994
Symbol NSUN2 Alias MISU;MRT5;SAKI;TRM4 Full Name NOP2/Sun RNA methyltransferase 2
Status Confidence Length 34053 bases Strand Minus strand
Position 5 : 6599239 - 6633291 RNA binding domain Methyltr_RsmB-F
Summary This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000420957 Methyltr_RsmB-F PF01189 6.7e-38 1
ENSP00000264670 Methyltr_RsmB-F PF01189 7.6e-38 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
28418038 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader. Xin Yang 2017-05-01 Cell research
34073722 A Circulating Exosome RNA Signature Is a Potential Diagnostic Marker for Pancreatic Cancer, a Systematic Study. Yixing Wu 2021-05-24 Cancers
34588546 Single-molecule RNA sequencing for simultaneous detection of m6A and 5mC. Takahito Ohshiro 2021-09-29 Scientific reports
36437944 The role of RNA modification in the generation of acquired drug resistance in glioma. Yu Yan 2022-01-01 Frontiers in genetics
33142933 The Roles of Host 5-Methylcytosine RNA Methyltransferases during Viral Infections. Maciej Wnuk 2020-10-31 International journal of molecular sciences
30476045 Extracellular membrane vesicles in the three domains of life and beyond. Sukhvinder Gill 2019-05-01 FEMS microbiology reviews
35186363 Azacytidine targeting SARS-CoV-2 viral RNA as a potential treatment for COVID-19. Xian Lin 2022-05-30 Science bulletin
28341602 Cytosolic YB-1 and NSUN2 are the only proteins recognizing specific motifs present in mRNAs enriched in exosomes. A Olga Kossinova 2017-06-01 Biochimica et biophysica acta. Proteins and proteomics
34345012 NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization. Jiachun Su 2021-09-01 Oncogene
30816500 Expression profiles of long noncoding RNAs associated with the NSUN2 gene in HepG2 cells. Zhen Sun 2019-04-01 Molecular medicine reports
22344696 Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA. E Jeffrey Squires 2012-06-01 Nucleic acids research
26625014 RNA epigenetics--chemical messages for posttranscriptional gene regulation. A Ian Roundtree 2016-02-01 Current opinion in chemical biology
36077143 Reorganization of the Landscape of Translated mRNAs in NSUN2-Deficient Cells and Specific Features of NSUN2 Target mRNAs. A Olga Kossinova 2022-08-28 International journal of molecular sciences
33093178 NSun2 promotes cell migration through methylating autotaxin mRNA. Xin Xu 2020-12-25 The Journal of biological chemistry
36601431 Dynamic regulation and key roles of ribonucleic acid methylation. Jia Zou 2022-01-01 Frontiers in cellular neuroscience
22395603 The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16. Xiaotian Zhang 2012-03-06 Nature communications
23871666 NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs. Shobbir Hussain 2013-07-25 Cell reports
25014650 Role of RNA methyltransferases in tissue renewal and pathology. Sandra Blanco 2014-12-01 Current opinion in cell biology
35484099 Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine. Chen Xue 2022-04-28 Signal transduction and targeted therapy
31415754 Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression. G David Courtney 2019-08-14 Cell host & microbe
32978516 Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma. Zhen Sun 2020-11-01 Oncogene

Transcripts

Name Transcript ID bp Protein Translation ID
NSUN2-201 ENST00000264670 3056 767aa ENSP00000264670
NSUN2-203 ENST00000504374 3217 202aa ENSP00000421783
NSUN2-205 ENST00000505892 3558 No protein -
NSUN2-208 ENST00000513888 1290 No protein -
NSUN2-206 ENST00000506139 2619 732aa ENSP00000420957
NSUN2-209 ENST00000514127 614 102aa ENSP00000426459
NSUN2-202 ENST00000502932 512 No protein -
NSUN2-207 ENST00000507888 715 No protein -
NSUN2-204 ENST00000505264 472 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
24081Body Fat Distribution4.5060000E-005-
42875Platelet Function Tests2.7579556E-006-
57249Dextroamphetamine9.0344000E-006-
57250Dextroamphetamine2.8045000E-006-
57255Dextroamphetamine2.8373000E-006-
57264Dextroamphetamine6.0481000E-005-
64139Adipose Tissue3E-622589738

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000037474homo_sapiensENSP0000041974038.541722.9167homo_sapiensENSP0000026467019.29611.4733
ENSG00000037474homo_sapiensENSP0000031898642.647123.8235homo_sapiensENSP0000026467018.904810.5606

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000037474homo_sapiensENSP0000026467099.217798.957nomascus_leucogenysENSNLEP0000001386899.217798.957
ENSG00000037474homo_sapiensENSP0000026467099.478599.3481pan_paniscusENSPPAP0000002600999.478599.3481
ENSG00000037474homo_sapiensENSP0000026467099.478599.2177pongo_abeliiENSPPYP0000001712796.704796.4512
ENSG00000037474homo_sapiensENSP0000026467099.608999.3481pan_troglodytesENSPTRP0000004572199.608999.3481
ENSG00000037474homo_sapiensENSP0000026467099.608999.6089gorilla_gorillaENSGGOP0000004289199.608999.6089
ENSG00000037474homo_sapiensENSP0000026467085.397779.661ornithorhynchus_anatinusENSOANP0000005293173.512968.5746
ENSG00000037474homo_sapiensENSP0000026467085.397779.9218sarcophilus_harrisiiENSSHAP0000001292382.183276.9134
ENSG00000037474homo_sapiensENSP0000026467044.458942.5033notamacropus_eugeniiENSMEUP0000000650945.406143.4088
ENSG00000037474homo_sapiensENSP0000026467061.277759.1917choloepus_hoffmanniENSCHOP0000000323082.311779.5096
ENSG00000037474homo_sapiensENSP0000026467080.052276.0104dasypus_novemcinctusENSDNOP0000001075089.63585.1095
ENSG00000037474homo_sapiensENSP0000026467055.149950.8475erinaceus_europaeusENSEEUP0000000154188.679281.761
ENSG00000037474homo_sapiensENSP0000026467074.576368.1877echinops_telfairiENSETEP0000000079677.506870.8672
ENSG00000037474homo_sapiensENSP0000026467097.001394.7849callithrix_jacchusENSCJAP0000007177968.319666.7585
ENSG00000037474homo_sapiensENSP0000026467098.435597.9139cercocebus_atysENSCATP0000004519398.435597.9139
ENSG00000037474homo_sapiensENSP0000026467094.263493.3507cercocebus_atysENSCATP0000003901498.233797.2826
ENSG00000037474homo_sapiensENSP0000026467094.915394.2634macaca_fascicularisENSMFAP0000002772093.094692.4552
ENSG00000037474homo_sapiensENSP0000026467098.174797.5228macaca_mulattaENSMMUP0000001731898.431497.7778
ENSG00000037474homo_sapiensENSP0000026467098.435597.7836macaca_nemestrinaENSMNEP0000001926498.435597.7836
ENSG00000037474homo_sapiensENSP0000026467098.565897.7836papio_anubisENSPANP0000002300198.309597.5293
ENSG00000037474homo_sapiensENSP0000026467094.524193.4811mandrillus_leucophaeusENSMLEP0000000388797.840896.7611
ENSG00000037474homo_sapiensENSP0000026467086.179982.7901tursiops_truncatusENSTTRP0000001202486.973783.5526
ENSG00000037474homo_sapiensENSP0000026467082.790179.2699vulpes_vulpesENSVVUP0000002411989.185485.3933
ENSG00000037474homo_sapiensENSP0000026467090.091386.8318mus_spretusMGP_SPRETEiJ_P003649891.281487.9789
ENSG00000037474homo_sapiensENSP0000026467091.655887.6141equus_asinusENSEASP0000502726292.621988.5376
ENSG00000037474homo_sapiensENSP0000026467087.353382.5293capra_hircusENSCHIP0000002092579.572475.1781
ENSG00000037474homo_sapiensENSP0000026467086.440781.2256loxodonta_africanaENSLAFP0000000788791.701286.1687
ENSG00000037474homo_sapiensENSP0000026467089.830586.7014panthera_leoENSPLOP0000000557191.989388.785
ENSG00000037474homo_sapiensENSP0000026467089.30985.1369ailuropoda_melanoleucaENSAMEP0000000293282.331778.4856
ENSG00000037474homo_sapiensENSP0000026467088.135683.1812bos_indicus_hybridENSBIXP0000504425883.87179.1563
ENSG00000037474homo_sapiensENSP0000026467081.486376.1408oryctolagus_cuniculusENSOCUP0000003418762.065557.994
ENSG00000037474homo_sapiensENSP0000026467091.655887.7445equus_caballusENSECAP0000001423992.621988.6693
ENSG00000037474homo_sapiensENSP0000026467090.35286.3103canis_lupus_familiarisENSCAFP0084503308068.54665.4797
ENSG00000037474homo_sapiensENSP0000026467089.700186.1799panthera_pardusENSPPRP0000000649991.733388.1333
ENSG00000037474homo_sapiensENSP0000026467084.48581.3559marmota_marmota_marmotaENSMMMP0000001889393.777190.3039
ENSG00000037474homo_sapiensENSP0000026467087.744584.485balaenoptera_musculusENSBMSP0001002073784.974781.8182
ENSG00000037474homo_sapiensENSP0000026467089.830585.1369cavia_porcellusENSCPOP0000000737090.065485.3595
ENSG00000037474homo_sapiensENSP0000026467089.960986.9622felis_catusENSFCAP0000003193975.657973.136
ENSG00000037474homo_sapiensENSP0000026467082.007877.7053ursus_americanusENSUAMP0000003261178.723474.5932
ENSG00000037474homo_sapiensENSP0000026467084.876179.4003monodelphis_domesticaENSMODP0000000248681.476876.2203
ENSG00000037474homo_sapiensENSP0000026467083.833179.2699bison_bison_bisonENSBBBP0000000848383.942679.3734
ENSG00000037474homo_sapiensENSP0000026467088.005284.7458monodon_monocerosENSMMNP0001500730691.093187.7193
ENSG00000037474homo_sapiensENSP0000026467089.178685.3977sus_scrofaENSSSCP0000006118868.951666.0282
ENSG00000037474homo_sapiensENSP0000026467093.741991.1343microcebus_murinusENSMICP0000002757588.875286.403
ENSG00000037474homo_sapiensENSP0000026467088.657183.1812octodon_degusENSODEP0000002501890.185784.6154
ENSG00000037474homo_sapiensENSP0000026467091.134387.2229jaculus_jaculusENSJJAP0000001041591.612187.6802
ENSG00000037474homo_sapiensENSP0000026467088.657184.3546ovis_aries_rambouilletENSOARP0002002986683.435679.3865
ENSG00000037474homo_sapiensENSP0000026467082.529377.575ursus_maritimusENSUMAP0000002950183.1878.1866
ENSG00000037474homo_sapiensENSP0000026467073.272570.013ochotona_princepsENSOPRP0000001034688.087884.1693
ENSG00000037474homo_sapiensENSP0000026467088.005284.7458delphinapterus_leucasENSDLEP0000000042387.096883.871
ENSG00000037474homo_sapiensENSP0000026467089.30985.3977physeter_catodonENSPCTP0000500284590.250386.2978
ENSG00000037474homo_sapiensENSP0000026467085.52880.1825physeter_catodonENSPCTP0000502457288.52982.9959
ENSG00000037474homo_sapiensENSP0000026467090.612887.0926mus_caroliMGP_CAROLIEiJ_P003483091.688788.1266
ENSG00000037474homo_sapiensENSP0000026467090.221686.9622mus_musculusENSMUSP0000010532191.413588.111
ENSG00000037474homo_sapiensENSP0000026467087.744584.2243dipodomys_ordiiENSDORP0000002700191.440287.7717
ENSG00000037474homo_sapiensENSP0000026467082.920578.8787mustela_putorius_furoENSMPUP0000000750488.333384.0278
ENSG00000037474homo_sapiensENSP0000026467097.522895.8279aotus_nancymaaeENSANAP0000003366097.522895.8279
ENSG00000037474homo_sapiensENSP0000026467097.131795.4368saimiri_boliviensis_boliviensisENSSBOP0000003836397.131795.4368
ENSG00000037474homo_sapiensENSP0000026467051.238649.0222vicugna_pacosENSVPAP0000000473978.675.2
ENSG00000037474homo_sapiensENSP0000026467098.565897.9139chlorocebus_sabaeusENSCSAP0000001337498.565897.9139
ENSG00000037474homo_sapiensENSP0000026467081.225678.0965tupaia_belangeriENSTBEP0000001277484.417381.1653
ENSG00000037474homo_sapiensENSP0000026467089.700186.0495mesocricetus_auratusENSMAUP0000001447791.125887.4172
ENSG00000037474homo_sapiensENSP0000026467087.874884.7458phocoena_sinusENSPSNP0000000229090.958287.7193
ENSG00000037474homo_sapiensENSP0000026467089.439486.0495camelus_dromedariusENSCDRP0000500671290.263286.8421
ENSG00000037474homo_sapiensENSP0000026467094.002690.6128carlito_syrichtaENSTSYP0000000523994.619491.2074
ENSG00000037474homo_sapiensENSP0000026467082.920579.4003panthera_tigris_altaicaENSPTIP0000001367186.062282.4087
ENSG00000037474homo_sapiensENSP0000026467089.830585.7888rattus_norvegicusENSRNOP0000002364188.107484.1432
ENSG00000037474homo_sapiensENSP0000026467094.393792.3077prolemur_simusENSPSMP0000001357994.393792.3077
ENSG00000037474homo_sapiensENSP0000026467089.700185.9192microtus_ochrogasterENSMOCP0000000944991.855887.984
ENSG00000037474homo_sapiensENSP0000026467029.204727.249sorex_araneusENSSARP0000000564949.015345.733
ENSG00000037474homo_sapiensENSP0000026467087.353383.9635peromyscus_maniculatus_bairdiiENSPEMP0000002532790.663187.1448
ENSG00000037474homo_sapiensENSP0000026467086.049580.9648bos_mutusENSBMUP0000003293478.571473.9286
ENSG00000037474homo_sapiensENSP0000026467090.091386.7014mus_spicilegusENSMSIP0000002080488.363285.0384
ENSG00000037474homo_sapiensENSP0000026467090.35286.5711cricetulus_griseus_chok1gshdENSCGRP0000100329791.909888.0637
ENSG00000037474homo_sapiensENSP0000026467089.048285.2673pteropus_vampyrusENSPVAP0000001002991.432487.5502
ENSG00000037474homo_sapiensENSP0000026467090.873587.0926myotis_lucifugusENSMLUP0000000877191.111187.3203
ENSG00000037474homo_sapiensENSP0000026467078.487673.794vombatus_ursinusENSVURP0001002802782.578977.6406
ENSG00000037474homo_sapiensENSP0000026467085.658480.704rhinolophus_ferrumequinumENSRFEP0001000402287.36782.3138
ENSG00000037474homo_sapiensENSP0000026467083.050878.8787neovison_visonENSNVIP0000000916189.466384.9719
ENSG00000037474homo_sapiensENSP0000026467088.135683.1812bos_taurusENSBTAP0000002055987.001382.1107
ENSG00000037474homo_sapiensENSP0000026467088.396384.6154heterocephalus_glaber_femaleENSHGLP0000001928485.28381.6352
ENSG00000037474homo_sapiensENSP0000026467098.696298.1747rhinopithecus_bietiENSRBIP0000002375798.696298.1747
ENSG00000037474homo_sapiensENSP0000026467082.529379.0091canis_lupus_dingoENSCAFP0002002927788.904585.1124
ENSG00000037474homo_sapiensENSP0000026467092.959688.9179sciurus_vulgarisENSSVLP0000500778893.815889.7368
ENSG00000037474homo_sapiensENSP0000026467086.049580.5737phascolarctos_cinereusENSPCIP0000001524582.810577.5408
ENSG00000037474homo_sapiensENSP0000026467062.711956.8448procavia_capensisENSPCAP0000001024763.708657.7483
ENSG00000037474homo_sapiensENSP0000026467090.091384.485nannospalax_galiliENSNGAP0000000536791.644685.9416
ENSG00000037474homo_sapiensENSP0000026467085.919281.6167bos_grunniensENSBGRP0000001482583.312379.1403
ENSG00000037474homo_sapiensENSP0000026467083.181277.575chinchilla_lanigeraENSCLAP0000000448291.666785.4885
ENSG00000037474homo_sapiensENSP0000026467088.787584.2243cervus_hanglu_yarkandensisENSCHYP0000002722289.019684.4444
ENSG00000037474homo_sapiensENSP0000026467088.526785.0065catagonus_wagneriENSCWAP0000000747278.58875.463
ENSG00000037474homo_sapiensENSP0000026467092.438189.1786ictidomys_tridecemlineatusENSSTOP0000000369493.535690.2375
ENSG00000037474homo_sapiensENSP0000026467093.611590.6128otolemur_garnettiiENSOGAP0000001344892.287989.3316
ENSG00000037474homo_sapiensENSP0000026467073.79471.3168cebus_imitatorENSCCAP0000003244192.032588.9431
ENSG00000037474homo_sapiensENSP0000026467097.783696.219cebus_imitatorENSCCAP0000001582996.774295.2258
ENSG00000037474homo_sapiensENSP0000026467092.568589.1786urocitellus_parryiiENSUPAP0001000826893.667590.2375
ENSG00000037474homo_sapiensENSP0000026467083.311678.2269moschus_moschiferusENSMMSP0000002756486.002780.7537
ENSG00000037474homo_sapiensENSP0000026467098.696298.1747rhinopithecus_roxellanaENSRROP0000002283698.696298.1747
ENSG00000037474homo_sapiensENSP0000026467090.482487.0926mus_pahariMGP_PahariEiJ_P002649391.556788.1266
ENSG00000037474homo_sapiensENSP0000026467091.786289.7001propithecus_coquereliENSPCOP0000000460795.39393.2249
ENSG00000037474homo_sapiensENSP0000026467050.456334.1591caenorhabditis_elegansY48G8AL.5a.156.578938.3041
ENSG00000037474homo_sapiensENSP0000026467058.148641.721ciona_intestinalisENSCINP0000001935268.195748.9297
ENSG00000037474homo_sapiensENSP0000026467027.900924.9022petromyzon_marinusENSPMAP0000000309875.886567.7305
ENSG00000037474homo_sapiensENSP0000026467058.670145.6323eptatretus_burgeriENSEBUP0000001052160.402746.9799
ENSG00000037474homo_sapiensENSP0000026467018.122612.7771eptatretus_burgeriENSEBUP0000000321450.545535.6364
ENSG00000037474homo_sapiensENSP0000026467076.923166.4928callorhinchus_miliiENSCMIP0000001654873.566163.591
ENSG00000037474homo_sapiensENSP0000026467021.642819.1656latimeria_chalumnaeENSLACP0000000550985.56775.7732
ENSG00000037474homo_sapiensENSP0000026467078.61870.6649lepisosteus_oculatusENSLOCP0000001066479.342171.3158
ENSG00000037474homo_sapiensENSP0000026467075.228264.9283clupea_harengusENSCHAP0000000889273.130563.1179
ENSG00000037474homo_sapiensENSP0000026467077.314268.3181danio_rerioENSDARP0000011899777.415168.4073
ENSG00000037474homo_sapiensENSP0000026467077.57568.4485carassius_auratusENSCARP0000009742075.699766.7939
ENSG00000037474homo_sapiensENSP0000026467078.096569.2308carassius_auratusENSCARP0000009857877.290368.5161
ENSG00000037474homo_sapiensENSP0000026467077.183866.7536astyanax_mexicanusENSAMXP0000001820978.933368.2667
ENSG00000037474homo_sapiensENSP0000026467078.226968.0574ictalurus_punctatusENSIPUP0000002192578.740268.5039
ENSG00000037474homo_sapiensENSP0000026467076.792766.6232esox_luciusENSELUP0000002542975.127565.1786
ENSG00000037474homo_sapiensENSP0000026467078.096567.4055electrophorus_electricusENSEEEP0000003885679.023868.2058
ENSG00000037474homo_sapiensENSP0000026467076.792767.1447oncorhynchus_kisutchENSOKIP0000503061275.416165.9411
ENSG00000037474homo_sapiensENSP0000026467077.183868.0574oncorhynchus_mykissENSOMYP0000008035477.690368.5039
ENSG00000037474homo_sapiensENSP0000026467076.923166.7536salmo_salarENSSSAP0000010084677.225167.0157
ENSG00000037474homo_sapiensENSP0000026467077.444667.4055salmo_truttaENSSTUP0000003828778.055267.9369
ENSG00000037474homo_sapiensENSP0000026467073.402963.3638gadus_morhuaENSGMOP0000002251275.066764.8
ENSG00000037474homo_sapiensENSP0000026467077.314268.0574fundulus_heteroclitusENSFHEP0000001621877.617868.3246
ENSG00000037474homo_sapiensENSP0000026467076.140866.7536poecilia_reticulataENSPREP0000002590077.76368.1758
ENSG00000037474homo_sapiensENSP0000026467076.010466.6232xiphophorus_maculatusENSXMAP0000001364277.218567.6821
ENSG00000037474homo_sapiensENSP0000026467076.531966.884oryzias_latipesENSORLP0000001797276.832567.1466
ENSG00000037474homo_sapiensENSP0000026467075.097864.9283cyclopterus_lumpusENSCLMP0000501393567.289758.1776
ENSG00000037474homo_sapiensENSP0000026467077.966167.6662oreochromis_niloticusENSONIP0000000977977.161366.9677
ENSG00000037474homo_sapiensENSP0000026467077.705367.2751haplochromis_burtoniENSHBUP0000001993877.102266.7529
ENSG00000037474homo_sapiensENSP0000026467077.966167.6662astatotilapia_callipteraENSACLP0000002102277.360967.141
ENSG00000037474homo_sapiensENSP0000026467076.923167.0143sparus_aurataENSSAUP0001001957277.733967.7207
ENSG00000037474homo_sapiensENSP0000026467076.010467.2751lates_calcariferENSLCAP0001005177176.912968.0739
ENSG00000037474homo_sapiensENSP0000026467082.007871.4472xenopus_tropicalisENSXETP0000005942478.822168.6717
ENSG00000037474homo_sapiensENSP0000026467082.268675.2282chrysemys_picta_belliiENSCPBP0000000850480.076173.2234
ENSG00000037474homo_sapiensENSP0000026467079.009170.7953sphenodon_punctatusENSSPUP0000001155877.592869.5262
ENSG00000037474homo_sapiensENSP0000026467078.61872.6206crocodylus_porosusENSCPRP0000502114580.939674.7651
ENSG00000037474homo_sapiensENSP0000026467073.011764.2764laticauda_laticaudataENSLLTP0000000077973.587464.7832
ENSG00000037474homo_sapiensENSP0000026467078.226968.4485notechis_scutatusENSNSUP0000001404474.074164.8148
ENSG00000037474homo_sapiensENSP0000026467077.705368.1877pseudonaja_textilisENSPTXP0000000541577.402667.9221
ENSG00000037474homo_sapiensENSP0000026467080.312972.2295anas_platyrhynchos_platyrhynchosENSAPLP0000001135574.396166.9082
ENSG00000037474homo_sapiensENSP0000026467081.355973.6636gallus_gallusENSGALP0001000074578.589471.1587
ENSG00000037474homo_sapiensENSP0000026467080.182572.3598meleagris_gallopavoENSMGAP0000002290278.846271.1538
ENSG00000037474homo_sapiensENSP0000026467076.010468.1877serinus_canariaENSSCAP0000000651466.781259.9084
ENSG00000037474homo_sapiensENSP0000026467082.138274.4459parus_majorENSPMJP0000000840974.644567.654
ENSG00000037474homo_sapiensENSP0000026467079.009172.2295anolis_carolinensisENSACAP0000000066674.630568.2266
ENSG00000037474homo_sapiensENSP0000026467040.156533.2464neolamprologus_brichardiENSNBRP0000000165867.692356.044
ENSG00000037474homo_sapiensENSP0000026467020.208615.9061neolamprologus_brichardiENSNBRP0000000169877.561
ENSG00000037474homo_sapiensENSP0000026467073.663664.4068naja_najaENSNNAP0000002126474.538365.1715
ENSG00000037474homo_sapiensENSP0000026467076.401669.3611podarcis_muralisENSPMRP0000001943473.618166.8342
ENSG00000037474homo_sapiensENSP0000026467071.838364.9283geospiza_fortisENSGFOP0000001261379.166771.5517
ENSG00000037474homo_sapiensENSP0000026467082.138274.1851taeniopygia_guttataENSTGUP0000003431976.923169.475
ENSG00000037474homo_sapiensENSP0000026467072.620662.3207erpetoichthys_calabaricusENSECRP0000001796878.672367.5141
ENSG00000037474homo_sapiensENSP0000026467074.054864.5372kryptolebias_marmoratusENSKMAP0000000113269.950760.9606
ENSG00000037474homo_sapiensENSP0000026467078.226970.4042salvator_merianaeENSSMRP0000001993179.260271.3342
ENSG00000037474homo_sapiensENSP0000026467074.315564.9283amphilophus_citrinellusENSACIP000000170037666.4
ENSG00000037474homo_sapiensENSP0000026467077.053566.7536dicentrarchus_labraxENSDLAP0000507020376.455466.2354
ENSG00000037474homo_sapiensENSP0000026467077.835768.5789amphiprion_perculaENSAPEP0000000382377.032367.871
ENSG00000037474homo_sapiensENSP0000026467053.324645.2412oryzias_sinensisENSOSIP0000001423375.045963.6697
ENSG00000037474homo_sapiensENSP0000026467074.445967.6662pelodiscus_sinensisENSPSIP0000001717779.637472.3849
ENSG00000037474homo_sapiensENSP0000026467076.010469.8827gopherus_evgoodeiENSGEVP0000500359780.524974.0331
ENSG00000037474homo_sapiensENSP0000026467081.616774.837chelonoidis_abingdoniiENSCABP0000002768579.542672.9352
ENSG00000037474homo_sapiensENSP0000026467077.053567.7966seriola_dumeriliENSSDUP0000000271676.753367.5325
ENSG00000037474homo_sapiensENSP0000026467076.531966.7536cottoperca_gobioENSCGOP0000000346676.631966.8407
ENSG00000037474homo_sapiensENSP0000026467074.967466.884struthio_camelus_australisENSSCUP0000000900176.666768.4
ENSG00000037474homo_sapiensENSP0000026467080.443371.8383anser_brachyrhynchusENSABRP0000002512278.39970.0127
ENSG00000037474homo_sapiensENSP0000026467068.9761.0169gasterosteus_aculeatusENSGACP0000001185981.384672
ENSG00000037474homo_sapiensENSP0000026467020.469417.3403cynoglossus_semilaevisENSCSEP0000001792282.631670
ENSG00000037474homo_sapiensENSP0000026467076.401667.5359poecilia_formosaENSPFOP0000000436878.133369.0667
ENSG00000037474homo_sapiensENSP0000026467077.835767.5359myripristis_murdjanENSMMDP0000501689670.650961.3018
ENSG00000037474homo_sapiensENSP0000026467077.444667.1447sander_luciopercaENSSLUP0000005552377.243266.9701
ENSG00000037474homo_sapiensENSP0000026467081.877473.9244strigops_habroptilaENSSHBP0000500272576.029168.6441
ENSG00000037474homo_sapiensENSP0000026467077.835768.5789amphiprion_ocellarisENSAOCP0000001453477.032367.871
ENSG00000037474homo_sapiensENSP0000026467082.007874.837terrapene_carolina_triunguisENSTMTP0000000452879.519672.5664
ENSG00000037474homo_sapiensENSP0000026467075.488966.3624hucho_huchoENSHHUP0000003612778.990469.4407
ENSG00000037474homo_sapiensENSP0000026467046.805738.3312hucho_huchoENSHHUP0000005202272.525359.3939
ENSG00000037474homo_sapiensENSP0000026467075.619365.5802betta_splendensENSBSLP0000001506177.025266.7995
ENSG00000037474homo_sapiensENSP0000026467075.749765.8409betta_splendensENSBSLP0000001628077.055766.9761
ENSG00000037474homo_sapiensENSP0000026467068.709360.6258pygocentrus_nattereriENSPNAP0000003603278.306169.0936
ENSG00000037474homo_sapiensENSP0000026467077.444667.4055anabas_testudineusENSATEP0000000996077.042867.0558
ENSG00000037474homo_sapiensENSP0000026467058.409440.9387ciona_savignyiENSCSAVP0000000287066.174346.3811
ENSG00000037474homo_sapiensENSP0000026467050.847533.7679saccharomyces_cerevisiaeYBL024W57.017537.8655
ENSG00000037474homo_sapiensENSP0000026467076.923167.4055seriola_lalandi_dorsalisENSSLDP0000000567777.124267.5817
ENSG00000037474homo_sapiensENSP0000026467076.792766.6232labrus_bergyltaENSLBEP0000003417476.692766.5365
ENSG00000037474homo_sapiensENSP0000026467078.096567.7966pundamilia_nyerereiENSPNYP0000001410377.490367.2704
ENSG00000037474homo_sapiensENSP0000026467077.314267.927mastacembelus_armatusENSMAMP0000000718376.913167.5746
ENSG00000037474homo_sapiensENSP0000026467077.183868.4485stegastes_partitusENSSPAP0000000476876.584767.9172
ENSG00000037474homo_sapiensENSP0000026467048.239937.6793oncorhynchus_tshawytschaENSOTSP0000507677366.907852.2604
ENSG00000037474homo_sapiensENSP0000026467076.662367.4055oncorhynchus_tshawytschaENSOTSP0000507177277.064267.7589
ENSG00000037474homo_sapiensENSP0000026467077.705368.3181acanthochromis_polyacanthusENSAPOP0000002151673.308764.4526
ENSG00000037474homo_sapiensENSP0000026467076.140868.8396aquila_chrysaetos_chrysaetosENSACCP0002001821379.890672.2298
ENSG00000037474homo_sapiensENSP0000026467075.880165.189nothobranchius_furzeriENSNFUP0001502951773.023862.7353
ENSG00000037474homo_sapiensENSP0000026467066.88459.322cyprinodon_variegatusENSCVAP0000001850477.727368.9394
ENSG00000037474homo_sapiensENSP0000026467075.619366.4928denticeps_clupeoidesENSDCDP0000005254075.324766.2338
ENSG00000037474homo_sapiensENSP0000026467077.705368.3181larimichthys_croceaENSLCRP0000503565777.604268.2292
ENSG00000037474homo_sapiensENSP0000026467076.792766.7536takifugu_rubripesENSTRUP0000002975577.567.3684
ENSG00000037474homo_sapiensENSP0000026467079.139571.5776ficedula_albicollisENSFALP0000002876066.630160.2634
ENSG00000037474homo_sapiensENSP0000026467076.662366.4928hippocampus_comesENSHCOP0000001668477.165466.9291
ENSG00000037474homo_sapiensENSP0000026467073.663664.7979cyprinus_carpio_carpioENSCCRP0000001628575.433966.3551
ENSG00000037474homo_sapiensENSP0000026467078.096568.97cyprinus_carpio_carpioENSCCRP0000012536971.224762.9013
ENSG00000037474homo_sapiensENSP0000026467082.007874.3155coturnix_japonicaENSCJPP0000501828569.733963.1929
ENSG00000037474homo_sapiensENSP0000026467076.140867.4055poecilia_latipinnaENSPLAP0000000523777.866768.9333
ENSG00000037474homo_sapiensENSP0000026467065.449857.236sinocyclocheilus_grahamiENSSGRP0000004242473.60764.3695
ENSG00000037474homo_sapiensENSP0000026467072.099164.0156sinocyclocheilus_grahamiENSSGRP0000002726776.69968.0999
ENSG00000037474homo_sapiensENSP0000026467077.835767.5359maylandia_zebraENSMZEP0000500006477.231667.0116
ENSG00000037474homo_sapiensENSP0000026467076.140866.4928tetraodon_nigroviridisENSTNIP000000121238069.863
ENSG00000037474homo_sapiensENSP0000026467078.096569.1004paramormyrops_kingsleyaeENSPKIP0000000889776.111867.3443
ENSG00000037474homo_sapiensENSP0000026467077.444668.1877scleropages_formosusENSSFOP0001507779572.527563.8584
ENSG00000037474homo_sapiensENSP0000026467081.616771.4472leptobrachium_leishanenseENSLLEP0000003294178.940769.1047
ENSG00000037474homo_sapiensENSP0000026467075.097865.8409scophthalmus_maximusENSSMAP0000003378573.563264.4955
ENSG00000037474homo_sapiensENSP0000026467075.880166.1017oryzias_melastigmaENSOMEP0000001210777.807567.7807

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000049enables tRNA binding1IBAHomo_sapiens(9606)Function
GO:0001701involved_in in utero embryonic development1IEAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005819located_in spindle1IEAHomo_sapiens(9606)Component
GO:0006400involved_in tRNA modification1TASHomo_sapiens(9606)Process
GO:0007286involved_in spermatid development1IEAHomo_sapiens(9606)Process
GO:0010793involved_in regulation of mRNA export from nucleus1IDAHomo_sapiens(9606)Process
GO:0016428enables tRNA (cytosine-5-)-methyltransferase activity3EXP,IBA,IDAHomo_sapiens(9606)Function
GO:0030488involved_in tRNA methylation2IBA,IDAHomo_sapiens(9606)Process
GO:0033313involved_in meiotic cell cycle checkpoint signaling1IEAHomo_sapiens(9606)Process
GO:0033391located_in chromatoid body1IEAHomo_sapiens(9606)Component
GO:0036416involved_in tRNA stabilization1ISSHomo_sapiens(9606)Process
GO:0048820involved_in hair follicle maturation1ISSHomo_sapiens(9606)Process
GO:0051301involved_in cell division1IEAHomo_sapiens(9606)Process
GO:0062152enables mRNA (cytidine-5-)-methyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1IDAHomo_sapiens(9606)Component
GO:0080009involved_in mRNA methylation1IDAHomo_sapiens(9606)Process
GO:2000736involved_in regulation of stem cell differentiation1ISSHomo_sapiens(9606)Process

Expression