RBP Type	Non-canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000013441	Gene ID	1195	Accession	2068
Symbol	CLK1	Alias	CLK;STY;CLK/STY	Full Name	CDC like kinase 1
Status	Confidence	Length	11654 bases	Strand	Minus strand
Position	2 : 200853009 - 200864662	RNA binding domain	N.A.
Summary	This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
36535935	In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors.	Anil A Aktas	2022-12-20	Blood cancer journal
24869919	N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation.	E Brandon Aubol	2014-08-15	The Biochemical journal
36968077	An AKT1-and TRIM21-mediated phosphodegron controls proteasomal degradation of HuR enabling cell survival under heat shock.	Sharanya Nag	2023-04-21	iScience
23519612	Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.	Yuying Liu	2013-05-01	Nucleic acids research
37342192	Targeting pre-mRNA splicing in cancers: roles, inhibitors, and therapeutic opportunities.	Shinsuke Araki	2023-01-01	Frontiers in oncology
27397683	Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing.	E Brandon Aubol	2016-07-21	Molecular cell
25529026	Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function.	M Malik Keshwani	2015-03-01	The Biochemical journal
25561496	Detained introns are a novel, widespread class of post-transcriptionally spliced introns.	L Paul Boutz	2015-01-01	Genes & development
34301951	Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia.	Masahiko Ajiro	2021-07-23	Nature communications

Name	Transcript ID	bp	Protein	Translation ID
CLK1-201	ENST00000321356	1847	484aa	ENSP00000326830
CLK1-207	ENST00000461981	3173	No protein	-
CLK1-208	ENST00000464454	484	No protein	-
CLK1-204	ENST00000432425	1682	136aa	ENSP00000400487
CLK1-210	ENST00000473565	3208	No protein	-
CLK1-209	ENST00000472679	461	No protein	-
CLK1-203	ENST00000409769	1192	307aa	ENSP00000386358
CLK1-202	ENST00000409403	1664	355aa	ENSP00000386875
CLK1-205	ENST00000434813	2026	526aa	ENSP00000394734
CLK1-206	ENST00000461326	435	No protein	-
CLK1-214	ENST00000496205	480	No protein	-
CLK1-213	ENST00000492793	596	No protein	-
CLK1-211	ENST00000481641	690	No protein	-
CLK1-212	ENST00000482590	626	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000013441	homo_sapiens	ENSP00000291823	27.1104	15.4221	homo_sapiens	ENSP00000326830	34.5041	19.6281
ENSG00000013441	homo_sapiens	ENSP00000356076	35.034	21.2585	homo_sapiens	ENSP00000326830	42.562	25.8264
ENSG00000013441	homo_sapiens	ENSP00000378505	63.4694	49.7959	homo_sapiens	ENSP00000326830	64.2562	50.4132
ENSG00000013441	homo_sapiens	ENSP00000494572	24.4032	14.7215	homo_sapiens	ENSP00000326830	38.0165	22.9339
ENSG00000013441	homo_sapiens	ENSP00000304226	16.7078	9.71193	homo_sapiens	ENSP00000326830	41.9422	24.3802
ENSG00000013441	homo_sapiens	ENSP00000385571	17.1953	10.7679	homo_sapiens	ENSP00000326830	42.562	26.6529
ENSG00000013441	homo_sapiens	ENSP00000357345	68.1363	52.7054	homo_sapiens	ENSP00000326830	70.2479	54.3388
ENSG00000013441	homo_sapiens	ENSP00000407442	17.0248	10.1653	homo_sapiens	ENSP00000326830	42.562	25.4132
ENSG00000013441	homo_sapiens	ENSP00000439697	30.7571	17.9811	homo_sapiens	ENSP00000326830	40.2893	23.5537
ENSG00000013441	homo_sapiens	ENSP00000316948	86.6944	79.21	homo_sapiens	ENSP00000326830	86.157	78.719
ENSG00000013441	homo_sapiens	ENSP00000342105	34.2762	20.6323	homo_sapiens	ENSP00000326830	42.562	25.6198
ENSG00000013441	homo_sapiens	ENSP00000312789	28.4579	17.6471	homo_sapiens	ENSP00000326830	36.9835	22.9339

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000013441	homo_sapiens	ENSP00000326830	87.8099	86.9835	nomascus_leucogenys	ENSNLEP00000033271	92.9978	92.1225
ENSG00000013441	homo_sapiens	ENSP00000326830	99.7934	99.5868	pan_paniscus	ENSPPAP00000027825	91.8251	91.635
ENSG00000013441	homo_sapiens	ENSP00000326830	99.7934	99.1736	pongo_abelii	ENSPPYP00000045313	86.4043	85.8676
ENSG00000013441	homo_sapiens	ENSP00000326830	100	99.7934	pan_troglodytes	ENSPTRP00000021858	92.0152	91.8251
ENSG00000013441	homo_sapiens	ENSP00000326830	99.5868	99.1736	gorilla_gorilla	ENSGGOP00000016984	88.7661	88.3978
ENSG00000013441	homo_sapiens	ENSP00000326830	91.3223	86.3636	ornithorhynchus_anatinus	ENSOANP00000025902	91.7012	86.722
ENSG00000013441	homo_sapiens	ENSP00000326830	90.2893	85.124	sarcophilus_harrisii	ENSSHAP00000014601	90.1031	84.9485
ENSG00000013441	homo_sapiens	ENSP00000326830	72.9339	71.281	choloepus_hoffmanni	ENSCHOP00000009931	86.9458	84.9754
ENSG00000013441	homo_sapiens	ENSP00000326830	68.1818	66.5289	dasypus_novemcinctus	ENSDNOP00000005831	96.7742	94.4282
ENSG00000013441	homo_sapiens	ENSP00000326830	57.0248	53.9256	erinaceus_europaeus	ENSEEUP00000004745	56.9072	53.8144
ENSG00000013441	homo_sapiens	ENSP00000326830	91.3223	88.4297	echinops_telfairi	ENSETEP00000012050	95.8785	92.8417
ENSG00000013441	homo_sapiens	ENSP00000326830	99.1736	98.1405	callithrix_jacchus	ENSCJAP00000046266	85.7143	84.8214
ENSG00000013441	homo_sapiens	ENSP00000326830	98.9669	98.1405	cercocebus_atys	ENSCATP00000013578	91.0646	90.3042
ENSG00000013441	homo_sapiens	ENSP00000326830	98.7603	97.9339	macaca_fascicularis	ENSMFAP00000015286	80.2013	79.5302
ENSG00000013441	homo_sapiens	ENSP00000326830	98.7603	97.9339	macaca_mulatta	ENSMMUP00000037921	80.2013	79.5302
ENSG00000013441	homo_sapiens	ENSP00000326830	98.7603	97.9339	macaca_nemestrina	ENSMNEP00000014427	80.2013	79.5302
ENSG00000013441	homo_sapiens	ENSP00000326830	91.1157	88.6364	papio_anubis	ENSPANP00000037645	70.1113	68.2035
ENSG00000013441	homo_sapiens	ENSP00000326830	99.1736	98.3471	mandrillus_leucophaeus	ENSMLEP00000011191	91.2548	90.4943
ENSG00000013441	homo_sapiens	ENSP00000326830	92.1488	88.843	tursiops_truncatus	ENSTTRP00000011178	91.9588	88.6598
ENSG00000013441	homo_sapiens	ENSP00000326830	97.5207	95.8678	vulpes_vulpes	ENSVVUP00000025948	97.5207	95.8678
ENSG00000013441	homo_sapiens	ENSP00000326830	93.8017	89.4628	mus_spretus	MGP_SPRETEiJ_P0018772	93.9959	89.648
ENSG00000013441	homo_sapiens	ENSP00000326830	97.5207	95.2479	equus_asinus	ENSEASP00005001627	78.5358	76.7055
ENSG00000013441	homo_sapiens	ENSP00000326830	97.9339	93.8017	capra_hircus	ENSCHIP00000019191	97.732	93.6082
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	95.2479	loxodonta_africana	ENSLAFP00000008288	97.7273	95.2479
ENSG00000013441	homo_sapiens	ENSP00000326830	97.314	94.8347	panthera_leo	ENSPLOP00000022167	97.314	94.8347
ENSG00000013441	homo_sapiens	ENSP00000326830	96.9008	95.0413	ailuropoda_melanoleuca	ENSAMEP00000006232	91.6016	89.8438
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	93.595	bos_indicus_hybrid	ENSBIXP00005046917	97.5258	93.4021
ENSG00000013441	homo_sapiens	ENSP00000326830	97.5207	95.6612	oryctolagus_cuniculus	ENSOCUP00000009180	97.5207	95.6612
ENSG00000013441	homo_sapiens	ENSP00000326830	97.314	95.2479	equus_caballus	ENSECAP00000013282	76.7101	75.0814
ENSG00000013441	homo_sapiens	ENSP00000326830	97.5207	95.8678	canis_lupus_familiaris	ENSCAFP00845040958	80.4089	79.046
ENSG00000013441	homo_sapiens	ENSP00000326830	97.314	94.8347	panthera_pardus	ENSPPRP00000026819	91.4563	89.1262
ENSG00000013441	homo_sapiens	ENSP00000326830	96.6942	94.8347	marmota_marmota_marmota	ENSMMMP00000013513	96.6942	94.8347
ENSG00000013441	homo_sapiens	ENSP00000326830	97.5207	94.8347	balaenoptera_musculus	ENSBMSP00010005242	97.3196	94.6392
ENSG00000013441	homo_sapiens	ENSP00000326830	94.6281	91.1157	cavia_porcellus	ENSCPOP00000014985	94.6281	91.1157
ENSG00000013441	homo_sapiens	ENSP00000326830	97.5207	95.0413	felis_catus	ENSFCAP00000050399	97.5207	95.0413
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	95.8678	ursus_americanus	ENSUAMP00000013968	97.7273	95.8678
ENSG00000013441	homo_sapiens	ENSP00000326830	90.9091	84.9174	monodelphis_domestica	ENSMODP00000018787	90.3491	84.3942
ENSG00000013441	homo_sapiens	ENSP00000326830	97.1074	92.9752	bison_bison_bison	ENSBBBP00000004041	97.5104	93.361
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	94.8347	monodon_monoceros	ENSMMNP00015011923	80.0338	77.665
ENSG00000013441	homo_sapiens	ENSP00000326830	97.1074	94.4215	sus_scrofa	ENSSSCP00000017052	97.1074	94.4215
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	95.0413	microcebus_murinus	ENSMICP00000028420	85.0719	82.7338
ENSG00000013441	homo_sapiens	ENSP00000326830	61.9835	60.5372	octodon_degus	ENSODEP00000012158	97.7199	95.4397
ENSG00000013441	homo_sapiens	ENSP00000326830	60.7438	59.2975	jaculus_jaculus	ENSJJAP00000025066	96.7105	94.4079
ENSG00000013441	homo_sapiens	ENSP00000326830	97.9339	93.8017	ovis_aries_rambouillet	ENSOARP00020020889	97.732	93.6082
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	95.8678	ursus_maritimus	ENSUMAP00000029639	97.7273	95.8678
ENSG00000013441	homo_sapiens	ENSP00000326830	86.157	84.5041	ochotona_princeps	ENSOPRP00000005209	86.5145	84.8548
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	94.8347	delphinapterus_leucas	ENSDLEP00000024257	80.0338	77.665
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	95.2479	physeter_catodon	ENSPCTP00005002335	91.3127	88.9961
ENSG00000013441	homo_sapiens	ENSP00000326830	93.1818	88.0165	mus_caroli	MGP_CAROLIEiJ_P0017763	94.3515	89.1213
ENSG00000013441	homo_sapiens	ENSP00000326830	93.595	89.4628	mus_musculus	ENSMUSP00000034868	93.7888	89.648
ENSG00000013441	homo_sapiens	ENSP00000326830	61.7769	60.5372	dipodomys_ordii	ENSDORP00000006929	94.6203	92.7215
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	96.0744	mustela_putorius_furo	ENSMPUP00000000198	97.7273	96.0744
ENSG00000013441	homo_sapiens	ENSP00000326830	99.1736	97.9339	aotus_nancymaae	ENSANAP00000018595	93.2039	92.0388
ENSG00000013441	homo_sapiens	ENSP00000326830	99.1736	97.5207	saimiri_boliviensis_boliviensis	ENSSBOP00000030838	90.2256	88.7218
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	95.8678	vicugna_pacos	ENSVPAP00000006202	97.7273	95.8678
ENSG00000013441	homo_sapiens	ENSP00000326830	99.3802	98.3471	chlorocebus_sabaeus	ENSCSAP00000007078	92.3225	91.3628
ENSG00000013441	homo_sapiens	ENSP00000326830	79.9587	78.3058	tupaia_belangeri	ENSTBEP00000000487	80.1242	78.4679
ENSG00000013441	homo_sapiens	ENSP00000326830	94.4215	89.6694	mesocricetus_auratus	ENSMAUP00000005696	94.4215	89.6694
ENSG00000013441	homo_sapiens	ENSP00000326830	97.9339	94.8347	phocoena_sinus	ENSPSNP00000025128	97.732	94.6392
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	95.8678	camelus_dromedarius	ENSCDRP00005011088	91.8447	90.0971
ENSG00000013441	homo_sapiens	ENSP00000326830	96.9008	94.8347	carlito_syrichta	ENSTSYP00000007796	91.6016	89.6484
ENSG00000013441	homo_sapiens	ENSP00000326830	97.314	94.8347	panthera_tigris_altaica	ENSPTIP00000014696	91.4563	89.1262
ENSG00000013441	homo_sapiens	ENSP00000326830	94.2149	90.0826	rattus_norvegicus	ENSRNOP00000038335	94.4099	90.2691
ENSG00000013441	homo_sapiens	ENSP00000326830	97.1074	95.2479	prolemur_simus	ENSPSMP00000026546	89.6947	87.9771
ENSG00000013441	homo_sapiens	ENSP00000326830	35.124	34.0909	microtus_ochrogaster	ENSMOCP00000006048	95.5056	92.6966
ENSG00000013441	homo_sapiens	ENSP00000326830	64.876	63.6364	sorex_araneus	ENSSARP00000008823	97.8193	95.9502
ENSG00000013441	homo_sapiens	ENSP00000326830	93.8017	89.4628	peromyscus_maniculatus_bairdii	ENSPEMP00000026364	93.9959	89.648
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	93.595	bos_mutus	ENSBMUP00000035789	97.5258	93.4021
ENSG00000013441	homo_sapiens	ENSP00000326830	93.8017	89.4628	mus_spicilegus	ENSMSIP00000027971	93.9959	89.648
ENSG00000013441	homo_sapiens	ENSP00000326830	94.4215	90.0826	cricetulus_griseus_chok1gshd	ENSCGRP00001018759	94.2268	89.8969
ENSG00000013441	homo_sapiens	ENSP00000326830	93.3884	91.5289	pteropus_vampyrus	ENSPVAP00000007662	93.3884	91.5289
ENSG00000013441	homo_sapiens	ENSP00000326830	95.2479	91.1157	myotis_lucifugus	ENSMLUP00000000314	87.4763	83.6812
ENSG00000013441	homo_sapiens	ENSP00000326830	89.2562	82.438	vombatus_ursinus	ENSVURP00010011497	88.7064	81.9302
ENSG00000013441	homo_sapiens	ENSP00000326830	96.6942	94.0083	rhinolophus_ferrumequinum	ENSRFEP00010027238	96.4948	93.8144
ENSG00000013441	homo_sapiens	ENSP00000326830	25.6198	24.7934	neovison_vison	ENSNVIP00000011254	94.6565	91.6031
ENSG00000013441	homo_sapiens	ENSP00000326830	62.1901	61.157	neovison_vison	ENSNVIP00000011296	98.0456	96.4169
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	93.595	bos_taurus	ENSBTAP00000007115	97.5258	93.4021
ENSG00000013441	homo_sapiens	ENSP00000326830	94.0083	90.2893	heterocephalus_glaber_female	ENSHGLP00000015832	94.0083	90.2893
ENSG00000013441	homo_sapiens	ENSP00000326830	90.2893	88.6364	rhinopithecus_bieti	ENSRBIP00000029841	90.1031	88.4536
ENSG00000013441	homo_sapiens	ENSP00000326830	97.5207	95.8678	canis_lupus_dingo	ENSCAFP00020005373	97.5207	95.8678
ENSG00000013441	homo_sapiens	ENSP00000326830	96.6942	94.6281	sciurus_vulgaris	ENSSVLP00005005037	96.6942	94.6281
ENSG00000013441	homo_sapiens	ENSP00000326830	89.4628	83.6777	phascolarctos_cinereus	ENSPCIP00000025905	88.5481	82.8221
ENSG00000013441	homo_sapiens	ENSP00000326830	81.6116	78.719	procavia_capensis	ENSPCAP00000005284	81.9502	79.0456
ENSG00000013441	homo_sapiens	ENSP00000326830	34.7107	34.2975	nannospalax_galili	ENSNGAP00000007042	94.9153	93.7853
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	93.595	bos_grunniens	ENSBGRP00000036949	97.5258	93.4021
ENSG00000013441	homo_sapiens	ENSP00000326830	93.3884	88.843	chinchilla_lanigera	ENSCLAP00000016679	93.3884	88.843
ENSG00000013441	homo_sapiens	ENSP00000326830	97.7273	94.2149	cervus_hanglu_yarkandensis	ENSCHYP00000007834	97.5258	94.0206
ENSG00000013441	homo_sapiens	ENSP00000326830	96.281	93.1818	catagonus_wagneri	ENSCWAP00000013340	97.4895	94.3515
ENSG00000013441	homo_sapiens	ENSP00000326830	96.6942	95.0413	ictidomys_tridecemlineatus	ENSSTOP00000008590	96.6942	95.0413
ENSG00000013441	homo_sapiens	ENSP00000326830	96.6942	94.0083	otolemur_garnettii	ENSOGAP00000011028	96.6942	94.0083
ENSG00000013441	homo_sapiens	ENSP00000326830	99.1736	98.1405	cebus_imitator	ENSCCAP00000007475	92.8433	91.8762
ENSG00000013441	homo_sapiens	ENSP00000326830	86.3636	82.6446	urocitellus_parryii	ENSUPAP00010019334	95	90.9091
ENSG00000013441	homo_sapiens	ENSP00000326830	97.5207	93.595	moschus_moschiferus	ENSMMSP00000032971	92.3679	88.6497
ENSG00000013441	homo_sapiens	ENSP00000326830	99.1736	98.3471	rhinopithecus_roxellana	ENSRROP00000022842	91.4286	90.6667
ENSG00000013441	homo_sapiens	ENSP00000326830	93.8017	89.6694	mus_pahari	MGP_PahariEiJ_P0073083	93.9959	89.8551
ENSG00000013441	homo_sapiens	ENSP00000326830	97.314	95.2479	propithecus_coquereli	ENSPCOP00000013159	90.0574	88.1453
ENSG00000013441	homo_sapiens	ENSP00000326830	39.876	23.3471	caenorhabditis_elegans	T04C10.1.1	21.8821	12.8118
ENSG00000013441	homo_sapiens	ENSP00000326830	29.7521	19.0083	caenorhabditis_elegans	C16A11.10.1	37.4026	23.8961
ENSG00000013441	homo_sapiens	ENSP00000326830	29.7521	17.1488	caenorhabditis_elegans	Y111B2A.1.1	37.4026	21.5584
ENSG00000013441	homo_sapiens	ENSP00000326830	39.2562	23.5537	drosophila_melanogaster	FBpp0289737	18.1471	10.8883
ENSG00000013441	homo_sapiens	ENSP00000326830	37.3967	22.7273	ciona_intestinalis	ENSCINP00000015935	31.3692	19.0641
ENSG00000013441	homo_sapiens	ENSP00000326830	76.2397	63.0165	callorhinchus_milii	ENSCMIP00000013914	74.3952	61.4919
ENSG00000013441	homo_sapiens	ENSP00000326830	71.4876	59.0909	latimeria_chalumnae	ENSLACP00000002811	72.0833	59.5833
ENSG00000013441	homo_sapiens	ENSP00000326830	71.6942	55.7851	danio_rerio	ENSDARP00000117099	72.4426	56.3674
ENSG00000013441	homo_sapiens	ENSP00000326830	71.281	56.405	carassius_auratus	ENSCARP00000093800	71.7256	56.7568
ENSG00000013441	homo_sapiens	ENSP00000326830	70.0413	55.5785	carassius_auratus	ENSCARP00000011335	71.822	56.9915
ENSG00000013441	homo_sapiens	ENSP00000326830	69.6281	55.9917	ictalurus_punctatus	ENSIPUP00000029736	70.5021	56.6946
ENSG00000013441	homo_sapiens	ENSP00000326830	72.314	56.8182	esox_lucius	ENSELUP00000025618	71.4286	56.1224
ENSG00000013441	homo_sapiens	ENSP00000326830	73.3471	57.8512	oncorhynchus_kisutch	ENSOKIP00005096047	69.3359	54.6875
ENSG00000013441	homo_sapiens	ENSP00000326830	69.8347	50.8264	gadus_morhua	ENSGMOP00000010011	53.6508	39.0476
ENSG00000013441	homo_sapiens	ENSP00000326830	59.2975	41.3223	fundulus_heteroclitus	ENSFHEP00000024302	64.2058	44.7427
ENSG00000013441	homo_sapiens	ENSP00000326830	39.0496	29.5455	poecilia_reticulata	ENSPREP00000020118	78.4232	59.3361
ENSG00000013441	homo_sapiens	ENSP00000326830	40.0826	30.1653	xiphophorus_maculatus	ENSXMAP00000015404	66.8966	50.3448
ENSG00000013441	homo_sapiens	ENSP00000326830	56.405	40.4959	oryzias_latipes	ENSORLP00000019340	62.9032	45.1613
ENSG00000013441	homo_sapiens	ENSP00000326830	47.9339	38.2231	cyclopterus_lumpus	ENSCLMP00005039080	74.8387	59.6774
ENSG00000013441	homo_sapiens	ENSP00000326830	42.1488	31.6116	oreochromis_niloticus	ENSONIP00000038156	81.2749	60.9562
ENSG00000013441	homo_sapiens	ENSP00000326830	41.9422	31.6116	haplochromis_burtoni	ENSHBUP00000012720	81.2	61.2
ENSG00000013441	homo_sapiens	ENSP00000326830	42.1488	31.6116	astatotilapia_calliptera	ENSACLP00000036190	81.6	61.2
ENSG00000013441	homo_sapiens	ENSP00000326830	51.2397	39.6694	sparus_aurata	ENSSAUP00010027637	74.9245	58.006
ENSG00000013441	homo_sapiens	ENSP00000326830	58.6777	44.8347	lates_calcarifer	ENSLCAP00010051493	71.7172	54.798
ENSG00000013441	homo_sapiens	ENSP00000326830	57.0248	43.3884	lates_calcarifer	ENSLCAP00010019968	68.3168	51.9802
ENSG00000013441	homo_sapiens	ENSP00000326830	77.8926	68.1818	xenopus_tropicalis	ENSXETP00000096137	78.5417	68.75
ENSG00000013441	homo_sapiens	ENSP00000326830	91.1157	84.5041	chrysemys_picta_bellii	ENSCPBP00000015928	91.1157	84.5041
ENSG00000013441	homo_sapiens	ENSP00000326830	81.405	73.3471	sphenodon_punctatus	ENSSPUP00000004021	87.9464	79.2411
ENSG00000013441	homo_sapiens	ENSP00000326830	89.876	82.6446	crocodylus_porosus	ENSCPRP00005012122	90.8142	83.5073
ENSG00000013441	homo_sapiens	ENSP00000326830	82.6446	72.7273	laticauda_laticaudata	ENSLLTP00000010326	81.1359	71.3996
ENSG00000013441	homo_sapiens	ENSP00000326830	82.8512	72.7273	notechis_scutatus	ENSNSUP00000018004	83.7161	73.4864
ENSG00000013441	homo_sapiens	ENSP00000326830	82.8512	72.7273	pseudonaja_textilis	ENSPTXP00000003554	84.2437	73.9496
ENSG00000013441	homo_sapiens	ENSP00000326830	88.843	82.438	anas_platyrhynchos_platyrhynchos	ENSAPLP00000015921	84.6457	78.5433
ENSG00000013441	homo_sapiens	ENSP00000326830	85.3306	75	gallus_gallus	ENSGALP00010037310	78.6667	69.1429
ENSG00000013441	homo_sapiens	ENSP00000326830	84.5041	74.3802	meleagris_gallopavo	ENSMGAP00000007773	81.1508	71.4286
ENSG00000013441	homo_sapiens	ENSP00000326830	86.9835	78.9256	anolis_carolinensis	ENSACAP00000016745	86.9835	78.9256
ENSG00000013441	homo_sapiens	ENSP00000326830	49.3802	36.9835	neolamprologus_brichardi	ENSNBRP00000018967	78.8779	59.0759
ENSG00000013441	homo_sapiens	ENSP00000326830	83.0579	72.7273	naja_naja	ENSNNAP00000014767	83.9248	73.4864
ENSG00000013441	homo_sapiens	ENSP00000326830	86.3636	78.719	podarcis_muralis	ENSPMRP00000004244	86.722	79.0456
ENSG00000013441	homo_sapiens	ENSP00000326830	77.8926	66.1157	erpetoichthys_calabaricus	ENSECRP00000027172	78.0538	66.2526
ENSG00000013441	homo_sapiens	ENSP00000326830	54.9587	41.3223	erpetoichthys_calabaricus	ENSECRP00000008442	73.6842	55.4017
ENSG00000013441	homo_sapiens	ENSP00000326830	54.1322	39.0496	kryptolebias_marmoratus	ENSKMAP00000004893	63.9024	46.0976
ENSG00000013441	homo_sapiens	ENSP00000326830	84.2975	72.5207	salvator_merianae	ENSSMRP00000025948	85	73.125
ENSG00000013441	homo_sapiens	ENSP00000326830	35.7438	25.2066	oryzias_javanicus	ENSOJAP00000035847	70.3252	49.5935
ENSG00000013441	homo_sapiens	ENSP00000326830	47.314	36.7769	amphilophus_citrinellus	ENSACIP00000016502	77.8912	60.5442
ENSG00000013441	homo_sapiens	ENSP00000326830	58.4711	45.8678	dicentrarchus_labrax	ENSDLAP00005038680	65.2074	51.1521
ENSG00000013441	homo_sapiens	ENSP00000326830	47.5207	36.5702	amphiprion_percula	ENSAPEP00000002133	73.955	56.9132
ENSG00000013441	homo_sapiens	ENSP00000326830	35.9504	26.2397	oryzias_sinensis	ENSOSIP00000035545	73.4177	53.5865
ENSG00000013441	homo_sapiens	ENSP00000326830	88.2231	82.0248	pelodiscus_sinensis	ENSPSIP00000003991	89.7059	83.4034
ENSG00000013441	homo_sapiens	ENSP00000326830	91.1157	84.9174	gopherus_evgoodei	ENSGEVP00005019391	91.3043	85.0932
ENSG00000013441	homo_sapiens	ENSP00000326830	90.2893	83.8843	chelonoidis_abingdonii	ENSCABP00000016697	90.6639	84.2324
ENSG00000013441	homo_sapiens	ENSP00000326830	48.1405	37.8099	seriola_dumerili	ENSSDUP00000012343	77.9264	61.204
ENSG00000013441	homo_sapiens	ENSP00000326830	42.9752	34.2975	cottoperca_gobio	ENSCGOP00000021892	79.6935	63.6015
ENSG00000013441	homo_sapiens	ENSP00000326830	89.6694	82.438	struthio_camelus_australis	ENSSCUP00000022454	88.5714	81.4286
ENSG00000013441	homo_sapiens	ENSP00000326830	88.843	82.2314	anser_brachyrhynchus	ENSABRP00000016400	84.8126	78.501
ENSG00000013441	homo_sapiens	ENSP00000326830	50.4132	37.6033	gasterosteus_aculeatus	ENSGACP00000027547	76.0125	56.6978
ENSG00000013441	homo_sapiens	ENSP00000326830	63.6364	45.6612	cynoglossus_semilaevis	ENSCSEP00000016149	60.6299	43.5039
ENSG00000013441	homo_sapiens	ENSP00000326830	55.9917	39.876	poecilia_formosa	ENSPFOP00000000491	67.2457	47.8908
ENSG00000013441	homo_sapiens	ENSP00000326830	51.0331	38.843	myripristis_murdjan	ENSMMDP00005033628	82.0598	62.4585
ENSG00000013441	homo_sapiens	ENSP00000326830	51.4463	40.7025	sander_lucioperca	ENSSLUP00000042210	76.8519	60.8025
ENSG00000013441	homo_sapiens	ENSP00000326830	40.7025	34.0909	strigops_habroptila	ENSSHBP00005025278	74.3396	62.2642
ENSG00000013441	homo_sapiens	ENSP00000326830	41.7355	31.1983	amphiprion_ocellaris	ENSAOCP00000009240	79.5276	59.4488
ENSG00000013441	homo_sapiens	ENSP00000326830	90.9091	84.5041	terrapene_carolina_triunguis	ENSTMTP00000013373	90.9091	84.5041
ENSG00000013441	homo_sapiens	ENSP00000326830	55.7851	41.7355	betta_splendens	ENSBSLP00000036014	72.973	54.5946
ENSG00000013441	homo_sapiens	ENSP00000326830	46.9008	35.7438	anabas_testudineus	ENSATEP00000033125	71.3836	54.4025
ENSG00000013441	homo_sapiens	ENSP00000326830	52.4793	41.1157	seriola_lalandi_dorsalis	ENSSLDP00000002570	67.0185	52.5066
ENSG00000013441	homo_sapiens	ENSP00000326830	41.9422	31.6116	labrus_bergylta	ENSLBEP00000006005	77.1863	58.1749
ENSG00000013441	homo_sapiens	ENSP00000326830	48.3471	36.3636	pundamilia_nyererei	ENSPNYP00000016959	77.7409	58.4718
ENSG00000013441	homo_sapiens	ENSP00000326830	59.2975	46.9008	mastacembelus_armatus	ENSMAMP00000000581	67.2131	53.1616
ENSG00000013441	homo_sapiens	ENSP00000326830	39.6694	28.9256	stegastes_partitus	ENSSPAP00000007112	68.0851	49.6454
ENSG00000013441	homo_sapiens	ENSP00000326830	73.3471	57.8512	oncorhynchus_tshawytscha	ENSOTSP00005028130	65.0183	51.2821
ENSG00000013441	homo_sapiens	ENSP00000326830	84.7107	77.0661	aquila_chrysaetos_chrysaetos	ENSACCP00020003840	83.1643	75.6592
ENSG00000013441	homo_sapiens	ENSP00000326830	55.9917	39.6694	cyprinodon_variegatus	ENSCVAP00000001547	68.4343	48.4848
ENSG00000013441	homo_sapiens	ENSP00000326830	59.2975	45.2479	larimichthys_crocea	ENSLCRP00005007978	67.6887	51.6509
ENSG00000013441	homo_sapiens	ENSP00000326830	39.0496	29.7521	larimichthys_crocea	ENSLCRP00005038767	65.1724	49.6552
ENSG00000013441	homo_sapiens	ENSP00000326830	58.0578	43.1818	takifugu_rubripes	ENSTRUP00000022132	69.3827	51.6049
ENSG00000013441	homo_sapiens	ENSP00000326830	47.9339	37.1901	hippocampus_comes	ENSHCOP00000022107	75.57	58.6319
ENSG00000013441	homo_sapiens	ENSP00000326830	69.6281	54.9587	cyprinus_carpio_carpio	ENSCCRP00000174645	71.7021	56.5957
ENSG00000013441	homo_sapiens	ENSP00000326830	70.6612	56.6116	cyprinus_carpio_carpio	ENSCCRP00000064740	70.5155	56.4948
ENSG00000013441	homo_sapiens	ENSP00000326830	61.3636	57.438	coturnix_japonica	ENSCJPP00005018578	87.3529	81.7647
ENSG00000013441	homo_sapiens	ENSP00000326830	39.6694	29.5455	poecilia_latipinna	ENSPLAP00000001381	77.4194	57.6613
ENSG00000013441	homo_sapiens	ENSP00000326830	70.4545	56.405	sinocyclocheilus_grahami	ENSSGRP00000021450	71.9409	57.5949
ENSG00000013441	homo_sapiens	ENSP00000326830	32.0248	26.2397	sinocyclocheilus_grahami	ENSSGRP00000023159	85.1648	69.7802
ENSG00000013441	homo_sapiens	ENSP00000326830	41.9422	31.8182	maylandia_zebra	ENSMZEP00005015691	81.2	61.6
ENSG00000013441	homo_sapiens	ENSP00000326830	40.9091	31.8182	tetraodon_nigroviridis	ENSTNIP00000010407	75.8621	59.0038
ENSG00000013441	homo_sapiens	ENSP00000326830	48.5537	40.2893	paramormyrops_kingsleyae	ENSPKIP00000001399	78.0731	64.784
ENSG00000013441	homo_sapiens	ENSP00000326830	78.5124	67.9752	leptobrachium_leishanense	ENSLLEP00000036394	79.4979	68.8285
ENSG00000013441	homo_sapiens	ENSP00000326830	62.6033	45.8678	scophthalmus_maximus	ENSSMAP00000062272	60.6	44.4
ENSG00000013441	homo_sapiens	ENSP00000326830	40.4959	29.9587	oryzias_melastigma	ENSOMEP00000036286	75.0958	55.5556

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0004674	enables protein serine/threonine kinase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0004712	enables protein serine/threonine/tyrosine kinase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0004713	enables protein tyrosine kinase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0004715	enables non-membrane spanning protein tyrosine kinase activity	1	TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0018105	involved_in peptidyl-serine phosphorylation	1	IEA	Homo_sapiens(9606)	Process
GO:0018107	involved_in peptidyl-threonine phosphorylation	1	IEA	Homo_sapiens(9606)	Process
GO:0018108	involved_in peptidyl-tyrosine phosphorylation	1	IBA	Homo_sapiens(9606)	Process
GO:0043484	involved_in regulation of RNA splicing	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0046777	involved_in protein autophosphorylation	1	IEA	Homo_sapiens(9606)	Process
GO:0106310	enables protein serine kinase activity	1	IEA	Homo_sapiens(9606)	Function