Ensembl ID ENSG00000013441 Gene ID 1195 Accession 2068
Gene Symbol CLK1 Alias CLK;STY;CLK/STY Full Name CDC like kinase 1
Position 2 : 200853009 - 200864662 Length 11654 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

ENSG00000013441 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000013441 CLK1 1.15 2.93e-30 KIRC
ENSG00000013441 CLK1 -0.6 4.30e-30 BRCA
ENSG00000013441 CLK1 -0.8 5.47e-11 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000013441 CLK1 tumor 20700505
ENSG00000013441 CLK1 cancer 21206969
ENSG00000013441 CLK1 tumor 22353034
ENSG00000013441 CLK1 tumor 24534158
ENSG00000013441 CLK1 cancer 25581376
ENSG00000013441 CLK1 tumors 26273588
ENSG00000013441 CLK1 tumor 27015110
ENSG00000013441 CLK1 breast cancer 27117709
ENSG00000013441 CLK1 cancer 27940419
ENSG00000013441 CLK1 cancer 29283381
ENSG00000013441 CLK1 cancers 29606096
ENSG00000013441 CLK1 cancer 29723265
ENSG00000013441 CLK1 tumor 29769258
ENSG00000013441 CLK1 cancer 29789342
ENSG00000013441 CLK1 cancer 29802995
ENSG00000013441 CLK1 Triple-Negative Breast Cancer 29866747
ENSG00000013441 CLK1 cancer 30108199
ENSG00000013441 CLK1 triple-negative breast cancer 30409083
ENSG00000013441 CLK1 cancer 30731399
ENSG00000013441 CLK1 tumor 31560935
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000013441 CLK1 MESO 0.00059 low
ENSG00000013441 CLK1 UVM 0.014 high
ENSG00000013441 CLK1 PAAD 0.011 low
ENSG00000013441 CLK1 ACC 0.0016 high
ENSG00000013441 CLK1 LGG 0.03 high
ENSG00000013441 CLK1 HNSC 0.0061 low
ENSG00000013441 CLK1 KICH 0.00041 low
ENSG00000013441 CLK1 LUAD 0.00073 low
ENSG00000013441 CLK1 PCPG 0.015 high
ENSG00000013441 CLK1 THYM 0.0028 low
ENSG00000013441 CLK1 COAD 0.01 high
ENSG00000013441 CLK1 ESCA 0.0068 high
ENSG00000013441 CLK1 OV 0.031 low
ENSG00000013441 CLK1 DLBC 0.0079 high
ENSG00000013441 CLK1 KIRC 0.00027 high
ENSG00000013441 CLK1 PRAD 0.038 high
ENSG00000013441 CLK1 BLCA 0.0012 low
ENSG00000013441 CLK1 LAML 0.023 low
ENSG00000013441 CLK1 GBM 0.05 low
ENSG00000013441 CLK1 CESC 0.039 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000013441 CLK1 CESC Amp 1.021671 0.141101 0.609852 0.132203
ENSG00000013441 CLK1 CESC Del 3.656165 0.113770 0.455272 0.216949
ENSG00000013441 CLK1 KIRP Amp 1.259300 0.072829 0.577568 0.170139
ENSG00000013441 CLK1 HNSC Del 5.275330 0.093954 0.335233 0.185824
ENSG00000013441 CLK1 BLCA Del 2.943100 0.110919 0.377248 0.355392
ENSG00000013441 CLK1 KIRC Del 0.920803 0.026246 0.539078 0.047348