Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000256525 Gene ID 11232 Accession 9180
Symbol POLG2 Alias HP55;POLB;PEOA4;POLGB;MTPOLB;MTDPS16;MTDPS16A;MTDPS16B;POLG-BETA Full Name DNA polymerase gamma 2, accessory subunit
Status Confidence Length 19270 bases Strand Minus strand
Position 17 : 64477785 - 64497054 RNA binding domain HGTP_anticodon
Summary This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009]

RNA binding domains (RBDs)

Literatures on RNA binding capacity

Transcripts

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression