Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions Kinase
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000248333 Gene ID 984 Accession 1729
Symbol CDK11B Alias p58;PK58;CDK11;CLK-1;CDC2L1;PITSLREA;p58CLK-1;CDK11-p46;CDK11-p58;p58CDC2L1;CDK11-p110 Full Name cyclin dependent kinase 11B
Status Confidence Length 23788 bases Strand Minus strand
Position 1 : 1635225 - 1659012 RNA binding domain N.A.
Summary This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

RNA binding proteomes (RBPomes)

Transcripts

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression