Ensembl ID ENSG00000248333 Gene ID 984 Accession 1729
Gene Symbol CDK11B Alias p58;PK58;CDK11;CLK-1;CDC2L1;PITSLREA;p58CLK-1;CDK11-p46;CDK11-p58;p58CDC2L1;CDK11-p110 Full Name cyclin dependent kinase 11B
Position 1 : 1635225 - 1659012 Length 23788 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

ENSG00000248333 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000248333 CDK11B tumor 22039459
ENSG00000248333 CDK11B Cancer 25837326
ENSG00000248333 CDK11B tumor 28901451
ENSG00000248333 CDK11B tumour 9516832
ENSG00000248333 CDK11B tumour 9516841
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000248333 CDK11B MESO 0.019 low
ENSG00000248333 CDK11B STAD 3e-04 low
ENSG00000248333 CDK11B UVM 0.0014 low
ENSG00000248333 CDK11B PAAD 0.022 high
ENSG00000248333 CDK11B UCEC 0.018 high
ENSG00000248333 CDK11B ACC 0.0097 high
ENSG00000248333 CDK11B LGG 2e-04 high
ENSG00000248333 CDK11B LUSC 0.029 low
ENSG00000248333 CDK11B READ 0.022 low
ENSG00000248333 CDK11B LUAD 0.033 low
ENSG00000248333 CDK11B PCPG 0.0019 low
ENSG00000248333 CDK11B THYM 0.018 low
ENSG00000248333 CDK11B BRCA 0.0032 low
ENSG00000248333 CDK11B COAD 0.04 low
ENSG00000248333 CDK11B DLBC 0.049 low
ENSG00000248333 CDK11B KIRC 7e-04 high
ENSG00000248333 CDK11B PRAD 0.016 high
ENSG00000248333 CDK11B BLCA 0.004 low
ENSG00000248333 CDK11B LAML 0.0011 high
ENSG00000248333 CDK11B GBM 0.023 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency