Ensembl ID ENSG00000204356 Gene ID
7936
Accession
13974
Symbol
NELFE
Alias
RD;RDP;RDBP;D6S45;NELF-E
Full Name
negative elongation factor complex member E
Status
Confidence
Length
6885 bases
Strand
Minus strand
Position
6 : 31952087 - 31958971
RNA binding domain
RRM_1
Summary
The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000397914
RRM_1
PF00076
1.6e-10
1
ENSP00000388400
RRM_1
PF00076
1.7e-10
1
ENSP00000364578
RRM_1
PF00076
2e-10
1
ENSP00000364574
RRM_1
PF00076
2e-10
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
36864891
Hepatic transcriptome profiling reveals early signatures associated with disease transition from non-alcoholic steatosis to steatohepatitis.
Nancy Magee
2022-12-01
Liver research
34188089
Constrained G4 structures unveil topology specificity of known and new G4 binding proteins.
A Pipier
2021-06-29
Scientific reports
31480283
An RNA Metabolism and Surveillance Quartet in the Major Histocompatibility Complex.
Danlei Zhou
2019-08-30
Cells
32155774
Presence of Antibodies Binding to Negative Elongation Factor E in Sarcoidosis.
Niklas Baerlecken
2020-03-06
Journal of clinical medicine
24453987
Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions.
M John Pagano
2014-01-01
PLoS genetics
29327913
Proteomic Analysis of the Downstream Signaling Network of PARP1.
Yuanli Zhen
2018-01-30
Biochemistry
27282391
Architecture and RNA binding of the human negative elongation factor.
M Seychelle Vos
2016-06-10
eLife
33526068
Overexpression of NELFE contributes to gastric cancer progression via Wnt/β-catenin signaling-mediated activation of CSNK2B expression.
Shijun Yu
2021-02-01
Journal of experimental & clinical cancer research : CR
28697339
Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma.
Hien Dang
2017-07-10
Cancer cell
11940650
Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.
Yuki Yamaguchi
2002-05-01
Molecular and cellular biology
32656996
The multifaceted role of PARP1 in RNA biogenesis.
Rebekah Eleazer
2021-03-01
Wiley interdisciplinary reviews. RNA
34295816
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.
Changyu Chen
2021-01-01
Frontiers in oncology
Name
Transcript ID
bp
Protein
Translation ID
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
12524 Breast Neoplasms 1.47E-10 17660530 13405 Macular Degeneration 5.68E-19 - 13462 Macular Degeneration 6.1E-10 - 16485 Macular Degeneration 4.889E-18 20385819 16555 Macular Degeneration 1.74E-09 20385819 67750 Macular Degeneration 3E-7 23577725 89467 Macular Degeneration 2E-10 23577725
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000204356 homo_sapiens ENSP00000403623 100 100 homo_sapiens ENSP00000364578 100 100 ENSG00000204356 homo_sapiens ENSP00000372660 100 100 homo_sapiens ENSP00000364578 100 100 ENSG00000204356 homo_sapiens ENSP00000394879 100 100 homo_sapiens ENSP00000364578 100 100 ENSG00000204356 homo_sapiens ENSP00000372834 100 100 homo_sapiens ENSP00000364578 100 100 ENSG00000204356 homo_sapiens ENSP00000393005 100 100 homo_sapiens ENSP00000364578 100 100
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000204356 homo_sapiens ENSP00000364578 86.0526 85.2632 nomascus_leucogenys ENSNLEP00000007844 90.5817 89.7507 ENSG00000204356 homo_sapiens ENSP00000364578 99.7368 99.4737 pan_paniscus ENSPPAP00000034205 97.4293 97.1722 ENSG00000204356 homo_sapiens ENSP00000364578 99.4737 99.2105 pongo_abelii ENSPPYP00000018418 97.1722 96.9152 ENSG00000204356 homo_sapiens ENSP00000364578 99.4737 99.2105 pan_troglodytes ENSPTRP00000063851 97.1722 96.9152 ENSG00000204356 homo_sapiens ENSP00000364578 98.4211 97.8947 gorilla_gorilla ENSGGOP00000019734 98.1627 97.6378 ENSG00000204356 homo_sapiens ENSP00000364578 93.6842 88.6842 ornithorhynchus_anatinus ENSOANP00000049680 87.0416 82.3961 ENSG00000204356 homo_sapiens ENSP00000364578 96.3158 91.3158 sarcophilus_harrisii ENSSHAP00000038194 87.3508 82.8162 ENSG00000204356 homo_sapiens ENSP00000364578 87.6316 83.9474 notamacropus_eugenii ENSMEUP00000005534 86.7188 83.0729 ENSG00000204356 homo_sapiens ENSP00000364578 65.7895 62.8947 choloepus_hoffmanni ENSCHOP00000004711 71.8391 68.6782 ENSG00000204356 homo_sapiens ENSP00000364578 98.9474 95.7895 dasypus_novemcinctus ENSDNOP00000020012 98.4293 95.288 ENSG00000204356 homo_sapiens ENSP00000364578 82.1053 75.5263 dasypus_novemcinctus ENSDNOP00000034483 90.6977 83.4302 ENSG00000204356 homo_sapiens ENSP00000364578 85 81.5789 erinaceus_europaeus ENSEEUP00000004572 84.555 81.1518 ENSG00000204356 homo_sapiens ENSP00000364578 99.4737 98.1579 callithrix_jacchus ENSCJAP00000004354 97.9275 96.6321 ENSG00000204356 homo_sapiens ENSP00000364578 94.4737 91.5789 cercocebus_atys ENSCATP00000009743 86.715 84.058 ENSG00000204356 homo_sapiens ENSP00000364578 98.9474 98.4211 macaca_fascicularis ENSMFAP00000003126 98.1723 97.6501 ENSG00000204356 homo_sapiens ENSP00000364578 85.7895 83.6842 macaca_mulatta ENSMMUP00000034023 96.4497 94.0828 ENSG00000204356 homo_sapiens ENSP00000364578 100 98.4211 macaca_nemestrina ENSMNEP00000017169 97.1867 95.6522 ENSG00000204356 homo_sapiens ENSP00000364578 100 98.4211 mandrillus_leucophaeus ENSMLEP00000012180 96.6921 95.1654 ENSG00000204356 homo_sapiens ENSP00000364578 96.5789 94.2105 tursiops_truncatus ENSTTRP00000005600 97.6064 95.2128 ENSG00000204356 homo_sapiens ENSP00000364578 93.6842 91.0526 vulpes_vulpes ENSVVUP00000031311 92.9504 90.3394 ENSG00000204356 homo_sapiens ENSP00000364578 94.4737 90.7895 mus_spretus MGP_SPRETEiJ_P0046211 96.2467 92.4933 ENSG00000204356 homo_sapiens ENSP00000364578 84.7368 79.4737 equus_asinus ENSEASP00005039600 82.1429 77.0408 ENSG00000204356 homo_sapiens ENSP00000364578 93.4211 90.5263 capra_hircus ENSCHIP00000011632 95.6873 92.7224 ENSG00000204356 homo_sapiens ENSP00000364578 98.9474 96.0526 loxodonta_africana ENSLAFP00000021481 98.4293 95.5497 ENSG00000204356 homo_sapiens ENSP00000364578 93.9474 90 panthera_leo ENSPLOP00000008362 87.715 84.0295 ENSG00000204356 homo_sapiens ENSP00000364578 98.4211 96.5789 ailuropoda_melanoleuca ENSAMEP00000002177 96.144 94.3445 ENSG00000204356 homo_sapiens ENSP00000364578 97.3684 94.7368 bos_indicus_hybrid ENSBIXP00005015512 97.1129 94.4882 ENSG00000204356 homo_sapiens ENSP00000364578 98.9474 96.0526 oryctolagus_cuniculus ENSOCUP00000006065 95.1899 92.4051 ENSG00000204356 homo_sapiens ENSP00000364578 99.2105 97.3684 equus_caballus ENSECAP00000033900 94.7236 92.9648 ENSG00000204356 homo_sapiens ENSP00000364578 91.3158 89.4737 canis_lupus_familiaris ENSCAFP00845019513 85.258 83.5381 ENSG00000204356 homo_sapiens ENSP00000364578 98.9474 97.3684 panthera_pardus ENSPPRP00000010142 97.1576 95.6072 ENSG00000204356 homo_sapiens ENSP00000364578 92.1053 89.2105 marmota_marmota_marmota ENSMMMP00000019424 86.4198 83.7037 ENSG00000204356 homo_sapiens ENSP00000364578 96.0526 93.9474 balaenoptera_musculus ENSBMSP00010025879 96.817 94.695 ENSG00000204356 homo_sapiens ENSP00000364578 99.2105 95 cavia_porcellus ENSCPOP00000026237 98.6911 94.5026 ENSG00000204356 homo_sapiens ENSP00000364578 98.6842 97.3684 felis_catus ENSFCAP00000004172 96.8992 95.6072 ENSG00000204356 homo_sapiens ENSP00000364578 98.4211 96.3158 ursus_americanus ENSUAMP00000031791 97.9058 95.8115 ENSG00000204356 homo_sapiens ENSP00000364578 97.3684 92.8947 monodelphis_domestica ENSMODP00000018834 92.5 88.25 ENSG00000204356 homo_sapiens ENSP00000364578 95 92.3684 monodon_monoceros ENSMMNP00015019715 95.756 93.1034 ENSG00000204356 homo_sapiens ENSP00000364578 92.3684 90.2632 sus_scrofa ENSSSCP00000001523 86.4532 84.4828 ENSG00000204356 homo_sapiens ENSP00000364578 95.5263 93.4211 microcebus_murinus ENSMICP00000002986 96.2865 94.1645 ENSG00000204356 homo_sapiens ENSP00000364578 93.6842 90.2632 octodon_degus ENSODEP00000024144 93.9314 90.5013 ENSG00000204356 homo_sapiens ENSP00000364578 88.1579 85 jaculus_jaculus ENSJJAP00000010406 92.2865 88.9807 ENSG00000204356 homo_sapiens ENSP00000364578 96.3158 93.9474 ovis_aries_rambouillet ENSOARP00020012494 97.0822 94.695 ENSG00000204356 homo_sapiens ENSP00000364578 98.4211 96.3158 ursus_maritimus ENSUMAP00000017261 97.9058 95.8115 ENSG00000204356 homo_sapiens ENSP00000364578 98.1579 94.4737 ochotona_princeps ENSOPRP00000003632 96.6321 93.0052 ENSG00000204356 homo_sapiens ENSP00000364578 89.4737 86.3158 delphinapterus_leucas ENSDLEP00000024454 78.8863 76.1021 ENSG00000204356 homo_sapiens ENSP00000364578 96.0526 94.2105 physeter_catodon ENSPCTP00005011825 96.817 94.9602 ENSG00000204356 homo_sapiens ENSP00000364578 94.4737 90.7895 mus_caroli MGP_CAROLIEiJ_P0044316 96.2467 92.4933 ENSG00000204356 homo_sapiens ENSP00000364578 93.4211 90 mus_musculus ENSMUSP00000094956 96.7302 93.188 ENSG00000204356 homo_sapiens ENSP00000364578 97.3684 94.7368 dipodomys_ordii ENSDORP00000011002 93.9086 91.3706 ENSG00000204356 homo_sapiens ENSP00000364578 98.4211 96.3158 mustela_putorius_furo ENSMPUP00000010503 96.144 94.0874 ENSG00000204356 homo_sapiens ENSP00000364578 99.2105 97.3684 aotus_nancymaae ENSANAP00000041959 97.416 95.6072 ENSG00000204356 homo_sapiens ENSP00000364578 99.4737 98.1579 saimiri_boliviensis_boliviensis ENSSBOP00000039708 97.6744 96.3824 ENSG00000204356 homo_sapiens ENSP00000364578 98.6842 97.3684 chlorocebus_sabaeus ENSCSAP00000005214 98.6842 97.3684 ENSG00000204356 homo_sapiens ENSP00000364578 93.4211 89.2105 mesocricetus_auratus ENSMAUP00000018144 96.9945 92.6229 ENSG00000204356 homo_sapiens ENSP00000364578 96.5789 93.9474 phocoena_sinus ENSPSNP00000030796 95.8225 93.2115 ENSG00000204356 homo_sapiens ENSP00000364578 96.5789 94.7368 camelus_dromedarius ENSCDRP00005018251 88.4337 86.747 ENSG00000204356 homo_sapiens ENSP00000364578 99.2105 96.8421 carlito_syrichta ENSTSYP00000030185 96.6667 94.359 ENSG00000204356 homo_sapiens ENSP00000364578 76.3158 70.7895 carlito_syrichta ENSTSYP00000023558 86.5672 80.2985 ENSG00000204356 homo_sapiens ENSP00000364578 98.9474 97.3684 panthera_tigris_altaica ENSPTIP00000001516 97.1576 95.6072 ENSG00000204356 homo_sapiens ENSP00000364578 94.7368 90.2632 rattus_norvegicus ENSRNOP00000000478 93.0233 88.6305 ENSG00000204356 homo_sapiens ENSP00000364578 96.8421 95.2632 prolemur_simus ENSPSMP00000027294 96.5879 95.0131 ENSG00000204356 homo_sapiens ENSP00000364578 95.5263 91.5789 microtus_ochrogaster ENSMOCP00000004478 97.8437 93.8005 ENSG00000204356 homo_sapiens ENSP00000364578 88.9474 85.7895 sorex_araneus ENSSARP00000003345 95.7507 92.3513 ENSG00000204356 homo_sapiens ENSP00000364578 94.7368 90 peromyscus_maniculatus_bairdii ENSPEMP00000016110 97.561 92.6829 ENSG00000204356 homo_sapiens ENSP00000364578 92.1053 88.6842 bos_mutus ENSBMUP00000008404 87.5 84.25 ENSG00000204356 homo_sapiens ENSP00000364578 94.2105 90.5263 mus_spicilegus ENSMSIP00000035809 91.5601 87.9795 ENSG00000204356 homo_sapiens ENSP00000364578 95.7895 91.3158 cricetulus_griseus_chok1gshd ENSCGRP00001016213 96.5517 92.0424 ENSG00000204356 homo_sapiens ENSP00000364578 96.8421 95.2632 pteropus_vampyrus ENSPVAP00000004861 98.3957 96.7914 ENSG00000204356 homo_sapiens ENSP00000364578 95 91.8421 myotis_lucifugus ENSMLUP00000000563 96.0106 92.8191 ENSG00000204356 homo_sapiens ENSP00000364578 90.2632 86.5789 myotis_lucifugus ENSMLUP00000018792 88.8601 85.2332 ENSG00000204356 homo_sapiens ENSP00000364578 83.6842 78.4211 myotis_lucifugus ENSMLUP00000019046 85.0267 79.6791 ENSG00000204356 homo_sapiens ENSP00000364578 90 83.6842 myotis_lucifugus ENSMLUP00000021350 90 83.6842 ENSG00000204356 homo_sapiens ENSP00000364578 88.1579 82.1053 myotis_lucifugus ENSMLUP00000018824 87.6963 81.6754 ENSG00000204356 homo_sapiens ENSP00000364578 97.3684 92.3684 vombatus_ursinus ENSVURP00010004949 95.3608 90.4639 ENSG00000204356 homo_sapiens ENSP00000364578 94.7368 93.1579 rhinolophus_ferrumequinum ENSRFEP00010004745 95.4907 93.8992 ENSG00000204356 homo_sapiens ENSP00000364578 98.4211 96.3158 neovison_vison ENSNVIP00000017282 96.6408 94.5736 ENSG00000204356 homo_sapiens ENSP00000364578 97.3684 94.7368 bos_taurus ENSBTAP00000009802 98.9305 96.2567 ENSG00000204356 homo_sapiens ENSP00000364578 86.3158 80.5263 heterocephalus_glaber_female ENSHGLP00000049767 83.6735 78.0612 ENSG00000204356 homo_sapiens ENSP00000364578 80.7895 77.8947 rhinopithecus_bieti ENSRBIP00000010131 94.4615 91.0769 ENSG00000204356 homo_sapiens ENSP00000364578 99.7368 97.6316 rhinopithecus_bieti ENSRBIP00000009393 97.1795 95.1282 ENSG00000204356 homo_sapiens ENSP00000364578 96.8421 95.5263 canis_lupus_dingo ENSCAFP00020000997 98.3957 97.0588 ENSG00000204356 homo_sapiens ENSP00000364578 98.1579 95.7895 sciurus_vulgaris ENSSVLP00005017628 96.3824 94.0568 ENSG00000204356 homo_sapiens ENSP00000364578 97.3684 92.6316 phascolarctos_cinereus ENSPCIP00000024946 93.9086 89.3401 ENSG00000204356 homo_sapiens ENSP00000364578 72.6316 70.5263 procavia_capensis ENSPCAP00000003846 73.0159 70.8995 ENSG00000204356 homo_sapiens ENSP00000364578 90.7895 89.2105 nannospalax_galili ENSNGAP00000015140 98.0114 96.3068 ENSG00000204356 homo_sapiens ENSP00000364578 97.3684 94.7368 bos_grunniens ENSBGRP00000032914 97.1129 94.4882 ENSG00000204356 homo_sapiens ENSP00000364578 97.6316 94.7368 chinchilla_lanigera ENSCLAP00000014015 98.1481 95.2381 ENSG00000204356 homo_sapiens ENSP00000364578 96.8421 93.9474 cervus_hanglu_yarkandensis ENSCHYP00000004688 97.0976 94.1953 ENSG00000204356 homo_sapiens ENSP00000364578 98.9474 97.1053 catagonus_wagneri ENSCWAP00000026184 97.1576 95.3488 ENSG00000204356 homo_sapiens ENSP00000364578 96.3158 94.2105 ictidomys_tridecemlineatus ENSSTOP00000016661 97.3404 95.2128 ENSG00000204356 homo_sapiens ENSP00000364578 98.1579 95.5263 otolemur_garnettii ENSOGAP00000008565 96.3824 93.7984 ENSG00000204356 homo_sapiens ENSP00000364578 99.4737 97.6316 cebus_imitator ENSCCAP00000002497 96.6752 94.8849 ENSG00000204356 homo_sapiens ENSP00000364578 96.3158 93.6842 urocitellus_parryii ENSUPAP00010025331 97.3404 94.6809 ENSG00000204356 homo_sapiens ENSP00000364578 96.3158 93.6842 moschus_moschiferus ENSMMSP00000019985 97.0822 94.4297 ENSG00000204356 homo_sapiens ENSP00000364578 99.7368 97.8947 rhinopithecus_roxellana ENSRROP00000037138 97.1795 95.3846 ENSG00000204356 homo_sapiens ENSP00000364578 94.2105 90.7895 mus_pahari MGP_PahariEiJ_P0043855 97.019 93.4959 ENSG00000204356 homo_sapiens ENSP00000364578 97.6316 95.2632 propithecus_coquereli ENSPCOP00000025436 96.3636 94.026 ENSG00000204356 homo_sapiens ENSP00000364578 43.6842 27.1053 ciona_intestinalis ENSCINP00000011919 53.8961 33.4416 ENSG00000204356 homo_sapiens ENSP00000364578 60.7895 43.4211 eptatretus_burgeri ENSEBUP00000027935 77.7778 55.5556 ENSG00000204356 homo_sapiens ENSP00000364578 66.8421 56.0526 latimeria_chalumnae ENSLACP00000002934 73.8372 61.9186 ENSG00000204356 homo_sapiens ENSP00000364578 32.3684 27.8947 lepisosteus_oculatus ENSLOCP00000000231 83.1081 71.6216 ENSG00000204356 homo_sapiens ENSP00000364578 75.2632 60.5263 clupea_harengus ENSCHAP00000026902 72.5888 58.3756 ENSG00000204356 homo_sapiens ENSP00000364578 74.7368 63.4211 danio_rerio ENSDARP00000124545 82.0809 69.6532 ENSG00000204356 homo_sapiens ENSP00000364578 75 62.3684 carassius_auratus ENSCARP00000077595 75.1979 62.533 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 65 astyanax_mexicanus ENSAMXP00000033478 78.7466 67.3025 ENSG00000204356 homo_sapiens ENSP00000364578 72.8947 61.0526 ictalurus_punctatus ENSIPUP00000023948 75.4768 63.2153 ENSG00000204356 homo_sapiens ENSP00000364578 72.6316 60.5263 esox_lucius ENSELUP00000004708 77.7465 64.7887 ENSG00000204356 homo_sapiens ENSP00000364578 69.2105 60 electrophorus_electricus ENSEEEP00000018336 79.697 69.0909 ENSG00000204356 homo_sapiens ENSP00000364578 72.8947 60.5263 oncorhynchus_kisutch ENSOKIP00005025156 77.809 64.6067 ENSG00000204356 homo_sapiens ENSP00000364578 65 53.1579 oncorhynchus_kisutch ENSOKIP00005040108 63.8243 52.1964 ENSG00000204356 homo_sapiens ENSP00000364578 69.7368 56.8421 oncorhynchus_mykiss ENSOMYP00000087878 59.417 48.4305 ENSG00000204356 homo_sapiens ENSP00000364578 72.6316 60 oncorhynchus_mykiss ENSOMYP00000087855 68.4864 56.5757 ENSG00000204356 homo_sapiens ENSP00000364578 72.8947 60 salmo_salar ENSSSAP00000098711 66.5865 54.8077 ENSG00000204356 homo_sapiens ENSP00000364578 72.8947 60.2632 salmo_salar ENSSSAP00000099679 77.809 64.3258 ENSG00000204356 homo_sapiens ENSP00000364578 72.3684 59.7368 salmo_trutta ENSSTUP00000065137 77.6836 64.1243 ENSG00000204356 homo_sapiens ENSP00000364578 72.8947 60 salmo_trutta ENSSTUP00000085869 66.2679 54.5455 ENSG00000204356 homo_sapiens ENSP00000364578 72.6316 61.3158 gadus_morhua ENSGMOP00000006356 73.9946 62.4665 ENSG00000204356 homo_sapiens ENSP00000364578 75.2632 64.7368 fundulus_heteroclitus ENSFHEP00000026068 81.25 69.8864 ENSG00000204356 homo_sapiens ENSP00000364578 68.9474 58.4211 poecilia_reticulata ENSPREP00000003241 80.6154 68.3077 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 65.2632 xiphophorus_maculatus ENSXMAP00000014102 80.5014 69.0808 ENSG00000204356 homo_sapiens ENSP00000364578 72.3684 63.1579 oryzias_latipes ENSORLP00000002424 74.9319 65.3951 ENSG00000204356 homo_sapiens ENSP00000364578 62.1053 50.2632 cyclopterus_lumpus ENSCLMP00005025342 72.6154 58.7692 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 65.5263 oreochromis_niloticus ENSONIP00000016992 81.1798 69.9438 ENSG00000204356 homo_sapiens ENSP00000364578 73.1579 61.3158 haplochromis_burtoni ENSHBUP00000021363 70.7379 59.2875 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 64.7368 astatotilapia_calliptera ENSACLP00000010034 80.7263 68.7151 ENSG00000204356 homo_sapiens ENSP00000364578 76.3158 66.0526 sparus_aurata ENSSAUP00010041510 75.3247 65.1948 ENSG00000204356 homo_sapiens ENSP00000364578 72.8947 62.6316 lates_calcarifer ENSLCAP00010039231 68.5644 58.9109 ENSG00000204356 homo_sapiens ENSP00000364578 75 63.4211 xenopus_tropicalis ENSXETP00000065135 76.8194 64.9596 ENSG00000204356 homo_sapiens ENSP00000364578 63.9474 55 chrysemys_picta_bellii ENSCPBP00000000235 83.7931 72.069 ENSG00000204356 homo_sapiens ENSP00000364578 77.3684 67.8947 sphenodon_punctatus ENSSPUP00000016774 87.2404 76.5579 ENSG00000204356 homo_sapiens ENSP00000364578 67.8947 55.5263 laticauda_laticaudata ENSLLTP00000015384 78.8991 64.526 ENSG00000204356 homo_sapiens ENSP00000364578 73.9474 62.1053 notechis_scutatus ENSNSUP00000013809 80.2857 67.4286 ENSG00000204356 homo_sapiens ENSP00000364578 59.2105 46.5789 pseudonaja_textilis ENSPTXP00000025408 53.5714 42.1429 ENSG00000204356 homo_sapiens ENSP00000364578 70.7895 60.5263 gallus_gallus ENSGALP00010039017 85.6688 73.2484 ENSG00000204356 homo_sapiens ENSP00000364578 32.1053 27.8947 meleagris_gallopavo ENSMGAP00000000743 64.5503 56.0847 ENSG00000204356 homo_sapiens ENSP00000364578 79.7368 69.4737 anolis_carolinensis ENSACAP00000011474 84.4011 73.5376 ENSG00000204356 homo_sapiens ENSP00000364578 73.4211 62.6316 neolamprologus_brichardi ENSNBRP00000024726 78.8136 67.2316 ENSG00000204356 homo_sapiens ENSP00000364578 73.9474 61.0526 naja_naja ENSNNAP00000003192 65.9624 54.4601 ENSG00000204356 homo_sapiens ENSP00000364578 67.6316 59.2105 podarcis_muralis ENSPMRP00000004932 83.7134 73.2899 ENSG00000204356 homo_sapiens ENSP00000364578 66.5789 58.1579 taeniopygia_guttata ENSTGUP00000021043 59.1121 51.6355 ENSG00000204356 homo_sapiens ENSP00000364578 77.1053 65.5263 erpetoichthys_calabaricus ENSECRP00000005303 81.3889 69.1667 ENSG00000204356 homo_sapiens ENSP00000364578 73.9474 63.9474 kryptolebias_marmoratus ENSKMAP00000003166 74.3386 64.2857 ENSG00000204356 homo_sapiens ENSP00000364578 75.5263 64.2105 salvator_merianae ENSSMRP00000021377 70.3431 59.8039 ENSG00000204356 homo_sapiens ENSP00000364578 70 61.3158 oryzias_javanicus ENSOJAP00000003634 76.4368 66.954 ENSG00000204356 homo_sapiens ENSP00000364578 70 60.2632 amphilophus_citrinellus ENSACIP00000021638 78.2353 67.3529 ENSG00000204356 homo_sapiens ENSP00000364578 75.7895 64.4737 dicentrarchus_labrax ENSDLAP00005069941 77.8378 66.2162 ENSG00000204356 homo_sapiens ENSP00000364578 74.2105 65 amphiprion_percula ENSAPEP00000001600 81.0345 70.977 ENSG00000204356 homo_sapiens ENSP00000364578 76.5789 66.8421 oryzias_sinensis ENSOSIP00000006944 81.7416 71.3483 ENSG00000204356 homo_sapiens ENSP00000364578 72.8947 64.7368 gopherus_evgoodei ENSGEVP00005028438 86.2928 76.6355 ENSG00000204356 homo_sapiens ENSP00000364578 50.5263 42.1053 chelonoidis_abingdonii ENSCABP00000031535 64.6465 53.8721 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 65.5263 seriola_dumerili ENSSDUP00000027751 80.2778 69.1667 ENSG00000204356 homo_sapiens ENSP00000364578 73.6842 61.3158 cottoperca_gobio ENSCGOP00000010913 69.4789 57.8164 ENSG00000204356 homo_sapiens ENSP00000364578 75.7895 63.6842 gasterosteus_aculeatus ENSGACP00000003845 79.7784 67.036 ENSG00000204356 homo_sapiens ENSP00000364578 71.0526 61.0526 cynoglossus_semilaevis ENSCSEP00000017683 79.4118 68.2353 ENSG00000204356 homo_sapiens ENSP00000364578 75.5263 65.2632 poecilia_formosa ENSPFOP00000002970 80.3922 69.4678 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 67.1053 myripristis_murdjan ENSMMDP00005009135 78.5326 69.2935 ENSG00000204356 homo_sapiens ENSP00000364578 73.9474 61.8421 sander_lucioperca ENSSLUP00000037721 79.1549 66.1972 ENSG00000204356 homo_sapiens ENSP00000364578 70.7895 61.5789 strigops_habroptila ENSSHBP00005007440 86.2179 75 ENSG00000204356 homo_sapiens ENSP00000364578 76.5789 66.8421 amphiprion_ocellaris ENSAOCP00000012751 80.8333 70.5556 ENSG00000204356 homo_sapiens ENSP00000364578 74.7368 65.7895 terrapene_carolina_triunguis ENSTMTP00000022055 87.3846 76.9231 ENSG00000204356 homo_sapiens ENSP00000364578 73.4211 60.2632 hucho_hucho ENSHHUP00000053182 66.5871 54.6539 ENSG00000204356 homo_sapiens ENSP00000364578 65.7895 52.6316 hucho_hucho ENSHHUP00000044632 61.7284 49.3827 ENSG00000204356 homo_sapiens ENSP00000364578 73.4211 62.8947 betta_splendens ENSBSLP00000024645 77.7159 66.5738 ENSG00000204356 homo_sapiens ENSP00000364578 76.5789 65.5263 pygocentrus_nattereri ENSPNAP00000005642 77.8075 66.5775 ENSG00000204356 homo_sapiens ENSP00000364578 76.3158 66.5789 anabas_testudineus ENSATEP00000039939 71.4286 62.3153 ENSG00000204356 homo_sapiens ENSP00000364578 38.9474 24.2105 ciona_savignyi ENSCSAVP00000007079 53.8182 33.4545 ENSG00000204356 homo_sapiens ENSP00000364578 72.1053 61.5789 seriola_lalandi_dorsalis ENSSLDP00000031794 79.6512 68.0233 ENSG00000204356 homo_sapiens ENSP00000364578 76.5789 65 labrus_bergylta ENSLBEP00000017111 79.0761 67.1196 ENSG00000204356 homo_sapiens ENSP00000364578 74.7368 63.9474 pundamilia_nyererei ENSPNYP00000023595 81.1429 69.4286 ENSG00000204356 homo_sapiens ENSP00000364578 73.4211 63.4211 mastacembelus_armatus ENSMAMP00000004465 74.4 64.2667 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 65.7895 stegastes_partitus ENSSPAP00000017165 63.9381 55.3097 ENSG00000204356 homo_sapiens ENSP00000364578 72.8947 60.2632 oncorhynchus_tshawytscha ENSOTSP00005067320 77.809 64.3258 ENSG00000204356 homo_sapiens ENSP00000364578 69.2105 56.8421 oncorhynchus_tshawytscha ENSOTSP00005025433 72.6519 59.6685 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 66.3158 acanthochromis_polyacanthus ENSAPOP00000006430 81.1798 70.7865 ENSG00000204356 homo_sapiens ENSP00000364578 54.7368 45.5263 aquila_chrysaetos_chrysaetos ENSACCP00020020811 62.0896 51.6418 ENSG00000204356 homo_sapiens ENSP00000364578 73.1579 63.9474 nothobranchius_furzeri ENSNFUP00015040472 72.7749 63.6126 ENSG00000204356 homo_sapiens ENSP00000364578 73.6842 64.4737 cyprinodon_variegatus ENSCVAP00000021206 80.2292 70.2006 ENSG00000204356 homo_sapiens ENSP00000364578 68.1579 57.1053 denticeps_clupeoides ENSDCDP00000025449 74.6398 62.536 ENSG00000204356 homo_sapiens ENSP00000364578 75.2632 64.7368 larimichthys_crocea ENSLCRP00005020136 75.6614 65.0794 ENSG00000204356 homo_sapiens ENSP00000364578 50.5263 43.1579 takifugu_rubripes ENSTRUP00000082865 79.3388 67.7686 ENSG00000204356 homo_sapiens ENSP00000364578 70 56.8421 hippocampus_comes ENSHCOP00000005451 65.1961 52.9412 ENSG00000204356 homo_sapiens ENSP00000364578 75 62.1053 cyprinus_carpio_carpio ENSCCRP00000025187 78.0822 64.6575 ENSG00000204356 homo_sapiens ENSP00000364578 75.7895 64.2105 poecilia_latipinna ENSPLAP00000014458 78.6885 66.6667 ENSG00000204356 homo_sapiens ENSP00000364578 42.3684 34.4737 sinocyclocheilus_grahami ENSSGRP00000046204 82.5641 67.1795 ENSG00000204356 homo_sapiens ENSP00000364578 71.0526 58.9474 sinocyclocheilus_grahami ENSSGRP00000023637 75 62.2222 ENSG00000204356 homo_sapiens ENSP00000364578 76.0526 64.7368 maylandia_zebra ENSMZEP00005035340 80.7263 68.7151 ENSG00000204356 homo_sapiens ENSP00000364578 23.4211 20.2632 tetraodon_nigroviridis ENSTNIP00000023100 80.1802 69.3694 ENSG00000204356 homo_sapiens ENSP00000364578 70 60.7895 paramormyrops_kingsleyae ENSPKIP00000031661 71.123 61.7647 ENSG00000204356 homo_sapiens ENSP00000364578 76.3158 65.2632 scleropages_formosus ENSSFOP00015026529 78.5908 67.2087 ENSG00000204356 homo_sapiens ENSP00000364578 71.0526 60.5263 leptobrachium_leishanense ENSLLEP00000019479 78.4884 66.8605 ENSG00000204356 homo_sapiens ENSP00000364578 77.1053 66.3158 scophthalmus_maximus ENSSMAP00000032919 80.4945 69.2308 ENSG00000204356 homo_sapiens ENSP00000364578 76.3158 65.7895 oryzias_melastigma ENSOMEP00000007482 66.9746 57.7367
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000122 involved_in negative regulation of transcription by RNA polymerase II 1 IEA Homo_sapiens(9606) Process GO:0000785 part_of chromatin 1 IDA Homo_sapiens(9606) Component GO:0003682 enables chromatin binding 1 IDA Homo_sapiens(9606) Function GO:0003723 enables RNA binding 3 HDA,IDA,NAS Homo_sapiens(9606) Function GO:0003729 enables mRNA binding 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 3 IDA,NAS Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 2 IDA,TAS Homo_sapiens(9606) Component GO:0005886 located_in plasma membrane 1 IDA Homo_sapiens(9606) Component GO:0016604 located_in nuclear body 1 IDA Homo_sapiens(9606) Component GO:0032021 part_of NELF complex 3 IBA,IDA,IPI Homo_sapiens(9606) Component GO:0034244 involved_in negative regulation of transcription elongation by RNA polymerase II 2 IBA,IDA Homo_sapiens(9606) Process GO:0045944 involved_in positive regulation of transcription by RNA polymerase II 1 IEA Homo_sapiens(9606) Process GO:0051179 involved_in localization 1 IDA Homo_sapiens(9606) Process GO:0051571 involved_in positive regulation of histone H3-K4 methylation 1 IEA Homo_sapiens(9606) Process GO:0070374 involved_in positive regulation of ERK1 and ERK2 cascade 1 IEA Homo_sapiens(9606) Process
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