Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_244 DataSet_01_294

Description

Ensembl ID ENSG00000204356 Gene ID 7936 Accession 13974
Symbol NELFE Alias RD;RDP;RDBP;D6S45;NELF-E Full Name negative elongation factor complex member E
Status Confidence Length 6885 bases Strand Minus strand
Position 6 : 31952087 - 31958971 RNA binding domain RRM_1
Summary The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000397914 RRM_1 PF00076 1.6e-10 1
ENSP00000388400 RRM_1 PF00076 1.7e-10 1
ENSP00000364578 RRM_1 PF00076 2e-10 1
ENSP00000364574 RRM_1 PF00076 2e-10 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36864891 Hepatic transcriptome profiling reveals early signatures associated with disease transition from non-alcoholic steatosis to steatohepatitis. Nancy Magee 2022-12-01 Liver research
34188089 Constrained G4 structures unveil topology specificity of known and new G4 binding proteins. A Pipier 2021-06-29 Scientific reports
31480283 An RNA Metabolism and Surveillance Quartet in the Major Histocompatibility Complex. Danlei Zhou 2019-08-30 Cells
32155774 Presence of Antibodies Binding to Negative Elongation Factor E in Sarcoidosis. Niklas Baerlecken 2020-03-06 Journal of clinical medicine
24453987 Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions. M John Pagano 2014-01-01 PLoS genetics
29327913 Proteomic Analysis of the Downstream Signaling Network of PARP1. Yuanli Zhen 2018-01-30 Biochemistry
27282391 Architecture and RNA binding of the human negative elongation factor. M Seychelle Vos 2016-06-10 eLife
33526068 Overexpression of NELFE contributes to gastric cancer progression via Wnt/β-catenin signaling-mediated activation of CSNK2B expression. Shijun Yu 2021-02-01 Journal of experimental & clinical cancer research : CR
28697339 Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma. Hien Dang 2017-07-10 Cancer cell
11940650 Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA. Yuki Yamaguchi 2002-05-01 Molecular and cellular biology
32656996 The multifaceted role of PARP1 in RNA biogenesis. Rebekah Eleazer 2021-03-01 Wiley interdisciplinary reviews. RNA
34295816 The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2. Changyu Chen 2021-01-01 Frontiers in oncology

Transcripts

Name Transcript ID bp Protein Translation ID

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
12524Breast Neoplasms1.47E-1017660530
13405Macular Degeneration5.68E-19-
13462Macular Degeneration6.1E-10-
16485Macular Degeneration4.889E-1820385819
16555Macular Degeneration1.74E-0920385819
67750Macular Degeneration3E-723577725
89467Macular Degeneration2E-1023577725

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000204356homo_sapiensENSP00000403623100100homo_sapiensENSP00000364578100100
ENSG00000204356homo_sapiensENSP00000372660100100homo_sapiensENSP00000364578100100
ENSG00000204356homo_sapiensENSP00000394879100100homo_sapiensENSP00000364578100100
ENSG00000204356homo_sapiensENSP00000372834100100homo_sapiensENSP00000364578100100
ENSG00000204356homo_sapiensENSP00000393005100100homo_sapiensENSP00000364578100100

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000204356homo_sapiensENSP0000036457886.052685.2632nomascus_leucogenysENSNLEP0000000784490.581789.7507
ENSG00000204356homo_sapiensENSP0000036457899.736899.4737pan_paniscusENSPPAP0000003420597.429397.1722
ENSG00000204356homo_sapiensENSP0000036457899.473799.2105pongo_abeliiENSPPYP0000001841897.172296.9152
ENSG00000204356homo_sapiensENSP0000036457899.473799.2105pan_troglodytesENSPTRP0000006385197.172296.9152
ENSG00000204356homo_sapiensENSP0000036457898.421197.8947gorilla_gorillaENSGGOP0000001973498.162797.6378
ENSG00000204356homo_sapiensENSP0000036457893.684288.6842ornithorhynchus_anatinusENSOANP0000004968087.041682.3961
ENSG00000204356homo_sapiensENSP0000036457896.315891.3158sarcophilus_harrisiiENSSHAP0000003819487.350882.8162
ENSG00000204356homo_sapiensENSP0000036457887.631683.9474notamacropus_eugeniiENSMEUP0000000553486.718883.0729
ENSG00000204356homo_sapiensENSP0000036457865.789562.8947choloepus_hoffmanniENSCHOP0000000471171.839168.6782
ENSG00000204356homo_sapiensENSP0000036457898.947495.7895dasypus_novemcinctusENSDNOP0000002001298.429395.288
ENSG00000204356homo_sapiensENSP0000036457882.105375.5263dasypus_novemcinctusENSDNOP0000003448390.697783.4302
ENSG00000204356homo_sapiensENSP000003645788581.5789erinaceus_europaeusENSEEUP0000000457284.55581.1518
ENSG00000204356homo_sapiensENSP0000036457899.473798.1579callithrix_jacchusENSCJAP0000000435497.927596.6321
ENSG00000204356homo_sapiensENSP0000036457894.473791.5789cercocebus_atysENSCATP0000000974386.71584.058
ENSG00000204356homo_sapiensENSP0000036457898.947498.4211macaca_fascicularisENSMFAP0000000312698.172397.6501
ENSG00000204356homo_sapiensENSP0000036457885.789583.6842macaca_mulattaENSMMUP0000003402396.449794.0828
ENSG00000204356homo_sapiensENSP0000036457810098.4211macaca_nemestrinaENSMNEP0000001716997.186795.6522
ENSG00000204356homo_sapiensENSP0000036457810098.4211mandrillus_leucophaeusENSMLEP0000001218096.692195.1654
ENSG00000204356homo_sapiensENSP0000036457896.578994.2105tursiops_truncatusENSTTRP0000000560097.606495.2128
ENSG00000204356homo_sapiensENSP0000036457893.684291.0526vulpes_vulpesENSVVUP0000003131192.950490.3394
ENSG00000204356homo_sapiensENSP0000036457894.473790.7895mus_spretusMGP_SPRETEiJ_P004621196.246792.4933
ENSG00000204356homo_sapiensENSP0000036457884.736879.4737equus_asinusENSEASP0000503960082.142977.0408
ENSG00000204356homo_sapiensENSP0000036457893.421190.5263capra_hircusENSCHIP0000001163295.687392.7224
ENSG00000204356homo_sapiensENSP0000036457898.947496.0526loxodonta_africanaENSLAFP0000002148198.429395.5497
ENSG00000204356homo_sapiensENSP0000036457893.947490panthera_leoENSPLOP0000000836287.71584.0295
ENSG00000204356homo_sapiensENSP0000036457898.421196.5789ailuropoda_melanoleucaENSAMEP0000000217796.14494.3445
ENSG00000204356homo_sapiensENSP0000036457897.368494.7368bos_indicus_hybridENSBIXP0000501551297.112994.4882
ENSG00000204356homo_sapiensENSP0000036457898.947496.0526oryctolagus_cuniculusENSOCUP0000000606595.189992.4051
ENSG00000204356homo_sapiensENSP0000036457899.210597.3684equus_caballusENSECAP0000003390094.723692.9648
ENSG00000204356homo_sapiensENSP0000036457891.315889.4737canis_lupus_familiarisENSCAFP0084501951385.25883.5381
ENSG00000204356homo_sapiensENSP0000036457898.947497.3684panthera_pardusENSPPRP0000001014297.157695.6072
ENSG00000204356homo_sapiensENSP0000036457892.105389.2105marmota_marmota_marmotaENSMMMP0000001942486.419883.7037
ENSG00000204356homo_sapiensENSP0000036457896.052693.9474balaenoptera_musculusENSBMSP0001002587996.81794.695
ENSG00000204356homo_sapiensENSP0000036457899.210595cavia_porcellusENSCPOP0000002623798.691194.5026
ENSG00000204356homo_sapiensENSP0000036457898.684297.3684felis_catusENSFCAP0000000417296.899295.6072
ENSG00000204356homo_sapiensENSP0000036457898.421196.3158ursus_americanusENSUAMP0000003179197.905895.8115
ENSG00000204356homo_sapiensENSP0000036457897.368492.8947monodelphis_domesticaENSMODP0000001883492.588.25
ENSG00000204356homo_sapiensENSP000003645789592.3684monodon_monocerosENSMMNP0001501971595.75693.1034
ENSG00000204356homo_sapiensENSP0000036457892.368490.2632sus_scrofaENSSSCP0000000152386.453284.4828
ENSG00000204356homo_sapiensENSP0000036457895.526393.4211microcebus_murinusENSMICP0000000298696.286594.1645
ENSG00000204356homo_sapiensENSP0000036457893.684290.2632octodon_degusENSODEP0000002414493.931490.5013
ENSG00000204356homo_sapiensENSP0000036457888.157985jaculus_jaculusENSJJAP0000001040692.286588.9807
ENSG00000204356homo_sapiensENSP0000036457896.315893.9474ovis_aries_rambouilletENSOARP0002001249497.082294.695
ENSG00000204356homo_sapiensENSP0000036457898.421196.3158ursus_maritimusENSUMAP0000001726197.905895.8115
ENSG00000204356homo_sapiensENSP0000036457898.157994.4737ochotona_princepsENSOPRP0000000363296.632193.0052
ENSG00000204356homo_sapiensENSP0000036457889.473786.3158delphinapterus_leucasENSDLEP0000002445478.886376.1021
ENSG00000204356homo_sapiensENSP0000036457896.052694.2105physeter_catodonENSPCTP0000501182596.81794.9602
ENSG00000204356homo_sapiensENSP0000036457894.473790.7895mus_caroliMGP_CAROLIEiJ_P004431696.246792.4933
ENSG00000204356homo_sapiensENSP0000036457893.421190mus_musculusENSMUSP0000009495696.730293.188
ENSG00000204356homo_sapiensENSP0000036457897.368494.7368dipodomys_ordiiENSDORP0000001100293.908691.3706
ENSG00000204356homo_sapiensENSP0000036457898.421196.3158mustela_putorius_furoENSMPUP0000001050396.14494.0874
ENSG00000204356homo_sapiensENSP0000036457899.210597.3684aotus_nancymaaeENSANAP0000004195997.41695.6072
ENSG00000204356homo_sapiensENSP0000036457899.473798.1579saimiri_boliviensis_boliviensisENSSBOP0000003970897.674496.3824
ENSG00000204356homo_sapiensENSP0000036457898.684297.3684chlorocebus_sabaeusENSCSAP0000000521498.684297.3684
ENSG00000204356homo_sapiensENSP0000036457893.421189.2105mesocricetus_auratusENSMAUP0000001814496.994592.6229
ENSG00000204356homo_sapiensENSP0000036457896.578993.9474phocoena_sinusENSPSNP0000003079695.822593.2115
ENSG00000204356homo_sapiensENSP0000036457896.578994.7368camelus_dromedariusENSCDRP0000501825188.433786.747
ENSG00000204356homo_sapiensENSP0000036457899.210596.8421carlito_syrichtaENSTSYP0000003018596.666794.359
ENSG00000204356homo_sapiensENSP0000036457876.315870.7895carlito_syrichtaENSTSYP0000002355886.567280.2985
ENSG00000204356homo_sapiensENSP0000036457898.947497.3684panthera_tigris_altaicaENSPTIP0000000151697.157695.6072
ENSG00000204356homo_sapiensENSP0000036457894.736890.2632rattus_norvegicusENSRNOP0000000047893.023388.6305
ENSG00000204356homo_sapiensENSP0000036457896.842195.2632prolemur_simusENSPSMP0000002729496.587995.0131
ENSG00000204356homo_sapiensENSP0000036457895.526391.5789microtus_ochrogasterENSMOCP0000000447897.843793.8005
ENSG00000204356homo_sapiensENSP0000036457888.947485.7895sorex_araneusENSSARP0000000334595.750792.3513
ENSG00000204356homo_sapiensENSP0000036457894.736890peromyscus_maniculatus_bairdiiENSPEMP0000001611097.56192.6829
ENSG00000204356homo_sapiensENSP0000036457892.105388.6842bos_mutusENSBMUP0000000840487.584.25
ENSG00000204356homo_sapiensENSP0000036457894.210590.5263mus_spicilegusENSMSIP0000003580991.560187.9795
ENSG00000204356homo_sapiensENSP0000036457895.789591.3158cricetulus_griseus_chok1gshdENSCGRP0000101621396.551792.0424
ENSG00000204356homo_sapiensENSP0000036457896.842195.2632pteropus_vampyrusENSPVAP0000000486198.395796.7914
ENSG00000204356homo_sapiensENSP000003645789591.8421myotis_lucifugusENSMLUP0000000056396.010692.8191
ENSG00000204356homo_sapiensENSP0000036457890.263286.5789myotis_lucifugusENSMLUP0000001879288.860185.2332
ENSG00000204356homo_sapiensENSP0000036457883.684278.4211myotis_lucifugusENSMLUP0000001904685.026779.6791
ENSG00000204356homo_sapiensENSP000003645789083.6842myotis_lucifugusENSMLUP000000213509083.6842
ENSG00000204356homo_sapiensENSP0000036457888.157982.1053myotis_lucifugusENSMLUP0000001882487.696381.6754
ENSG00000204356homo_sapiensENSP0000036457897.368492.3684vombatus_ursinusENSVURP0001000494995.360890.4639
ENSG00000204356homo_sapiensENSP0000036457894.736893.1579rhinolophus_ferrumequinumENSRFEP0001000474595.490793.8992
ENSG00000204356homo_sapiensENSP0000036457898.421196.3158neovison_visonENSNVIP0000001728296.640894.5736
ENSG00000204356homo_sapiensENSP0000036457897.368494.7368bos_taurusENSBTAP0000000980298.930596.2567
ENSG00000204356homo_sapiensENSP0000036457886.315880.5263heterocephalus_glaber_femaleENSHGLP0000004976783.673578.0612
ENSG00000204356homo_sapiensENSP0000036457880.789577.8947rhinopithecus_bietiENSRBIP0000001013194.461591.0769
ENSG00000204356homo_sapiensENSP0000036457899.736897.6316rhinopithecus_bietiENSRBIP0000000939397.179595.1282
ENSG00000204356homo_sapiensENSP0000036457896.842195.5263canis_lupus_dingoENSCAFP0002000099798.395797.0588
ENSG00000204356homo_sapiensENSP0000036457898.157995.7895sciurus_vulgarisENSSVLP0000501762896.382494.0568
ENSG00000204356homo_sapiensENSP0000036457897.368492.6316phascolarctos_cinereusENSPCIP0000002494693.908689.3401
ENSG00000204356homo_sapiensENSP0000036457872.631670.5263procavia_capensisENSPCAP0000000384673.015970.8995
ENSG00000204356homo_sapiensENSP0000036457890.789589.2105nannospalax_galiliENSNGAP0000001514098.011496.3068
ENSG00000204356homo_sapiensENSP0000036457897.368494.7368bos_grunniensENSBGRP0000003291497.112994.4882
ENSG00000204356homo_sapiensENSP0000036457897.631694.7368chinchilla_lanigeraENSCLAP0000001401598.148195.2381
ENSG00000204356homo_sapiensENSP0000036457896.842193.9474cervus_hanglu_yarkandensisENSCHYP0000000468897.097694.1953
ENSG00000204356homo_sapiensENSP0000036457898.947497.1053catagonus_wagneriENSCWAP0000002618497.157695.3488
ENSG00000204356homo_sapiensENSP0000036457896.315894.2105ictidomys_tridecemlineatusENSSTOP0000001666197.340495.2128
ENSG00000204356homo_sapiensENSP0000036457898.157995.5263otolemur_garnettiiENSOGAP0000000856596.382493.7984
ENSG00000204356homo_sapiensENSP0000036457899.473797.6316cebus_imitatorENSCCAP0000000249796.675294.8849
ENSG00000204356homo_sapiensENSP0000036457896.315893.6842urocitellus_parryiiENSUPAP0001002533197.340494.6809
ENSG00000204356homo_sapiensENSP0000036457896.315893.6842moschus_moschiferusENSMMSP0000001998597.082294.4297
ENSG00000204356homo_sapiensENSP0000036457899.736897.8947rhinopithecus_roxellanaENSRROP0000003713897.179595.3846
ENSG00000204356homo_sapiensENSP0000036457894.210590.7895mus_pahariMGP_PahariEiJ_P004385597.01993.4959
ENSG00000204356homo_sapiensENSP0000036457897.631695.2632propithecus_coquereliENSPCOP0000002543696.363694.026
ENSG00000204356homo_sapiensENSP0000036457843.684227.1053ciona_intestinalisENSCINP0000001191953.896133.4416
ENSG00000204356homo_sapiensENSP0000036457860.789543.4211eptatretus_burgeriENSEBUP0000002793577.777855.5556
ENSG00000204356homo_sapiensENSP0000036457866.842156.0526latimeria_chalumnaeENSLACP0000000293473.837261.9186
ENSG00000204356homo_sapiensENSP0000036457832.368427.8947lepisosteus_oculatusENSLOCP0000000023183.108171.6216
ENSG00000204356homo_sapiensENSP0000036457875.263260.5263clupea_harengusENSCHAP0000002690272.588858.3756
ENSG00000204356homo_sapiensENSP0000036457874.736863.4211danio_rerioENSDARP0000012454582.080969.6532
ENSG00000204356homo_sapiensENSP000003645787562.3684carassius_auratusENSCARP0000007759575.197962.533
ENSG00000204356homo_sapiensENSP0000036457876.052665astyanax_mexicanusENSAMXP0000003347878.746667.3025
ENSG00000204356homo_sapiensENSP0000036457872.894761.0526ictalurus_punctatusENSIPUP0000002394875.476863.2153
ENSG00000204356homo_sapiensENSP0000036457872.631660.5263esox_luciusENSELUP0000000470877.746564.7887
ENSG00000204356homo_sapiensENSP0000036457869.210560electrophorus_electricusENSEEEP0000001833679.69769.0909
ENSG00000204356homo_sapiensENSP0000036457872.894760.5263oncorhynchus_kisutchENSOKIP0000502515677.80964.6067
ENSG00000204356homo_sapiensENSP000003645786553.1579oncorhynchus_kisutchENSOKIP0000504010863.824352.1964
ENSG00000204356homo_sapiensENSP0000036457869.736856.8421oncorhynchus_mykissENSOMYP0000008787859.41748.4305
ENSG00000204356homo_sapiensENSP0000036457872.631660oncorhynchus_mykissENSOMYP0000008785568.486456.5757
ENSG00000204356homo_sapiensENSP0000036457872.894760salmo_salarENSSSAP0000009871166.586554.8077
ENSG00000204356homo_sapiensENSP0000036457872.894760.2632salmo_salarENSSSAP0000009967977.80964.3258
ENSG00000204356homo_sapiensENSP0000036457872.368459.7368salmo_truttaENSSTUP0000006513777.683664.1243
ENSG00000204356homo_sapiensENSP0000036457872.894760salmo_truttaENSSTUP0000008586966.267954.5455
ENSG00000204356homo_sapiensENSP0000036457872.631661.3158gadus_morhuaENSGMOP0000000635673.994662.4665
ENSG00000204356homo_sapiensENSP0000036457875.263264.7368fundulus_heteroclitusENSFHEP0000002606881.2569.8864
ENSG00000204356homo_sapiensENSP0000036457868.947458.4211poecilia_reticulataENSPREP0000000324180.615468.3077
ENSG00000204356homo_sapiensENSP0000036457876.052665.2632xiphophorus_maculatusENSXMAP0000001410280.501469.0808
ENSG00000204356homo_sapiensENSP0000036457872.368463.1579oryzias_latipesENSORLP0000000242474.931965.3951
ENSG00000204356homo_sapiensENSP0000036457862.105350.2632cyclopterus_lumpusENSCLMP0000502534272.615458.7692
ENSG00000204356homo_sapiensENSP0000036457876.052665.5263oreochromis_niloticusENSONIP0000001699281.179869.9438
ENSG00000204356homo_sapiensENSP0000036457873.157961.3158haplochromis_burtoniENSHBUP0000002136370.737959.2875
ENSG00000204356homo_sapiensENSP0000036457876.052664.7368astatotilapia_callipteraENSACLP0000001003480.726368.7151
ENSG00000204356homo_sapiensENSP0000036457876.315866.0526sparus_aurataENSSAUP0001004151075.324765.1948
ENSG00000204356homo_sapiensENSP0000036457872.894762.6316lates_calcariferENSLCAP0001003923168.564458.9109
ENSG00000204356homo_sapiensENSP000003645787563.4211xenopus_tropicalisENSXETP0000006513576.819464.9596
ENSG00000204356homo_sapiensENSP0000036457863.947455chrysemys_picta_belliiENSCPBP0000000023583.793172.069
ENSG00000204356homo_sapiensENSP0000036457877.368467.8947sphenodon_punctatusENSSPUP0000001677487.240476.5579
ENSG00000204356homo_sapiensENSP0000036457867.894755.5263laticauda_laticaudataENSLLTP0000001538478.899164.526
ENSG00000204356homo_sapiensENSP0000036457873.947462.1053notechis_scutatusENSNSUP0000001380980.285767.4286
ENSG00000204356homo_sapiensENSP0000036457859.210546.5789pseudonaja_textilisENSPTXP0000002540853.571442.1429
ENSG00000204356homo_sapiensENSP0000036457870.789560.5263gallus_gallusENSGALP0001003901785.668873.2484
ENSG00000204356homo_sapiensENSP0000036457832.105327.8947meleagris_gallopavoENSMGAP0000000074364.550356.0847
ENSG00000204356homo_sapiensENSP0000036457879.736869.4737anolis_carolinensisENSACAP0000001147484.401173.5376
ENSG00000204356homo_sapiensENSP0000036457873.421162.6316neolamprologus_brichardiENSNBRP0000002472678.813667.2316
ENSG00000204356homo_sapiensENSP0000036457873.947461.0526naja_najaENSNNAP0000000319265.962454.4601
ENSG00000204356homo_sapiensENSP0000036457867.631659.2105podarcis_muralisENSPMRP0000000493283.713473.2899
ENSG00000204356homo_sapiensENSP0000036457866.578958.1579taeniopygia_guttataENSTGUP0000002104359.112151.6355
ENSG00000204356homo_sapiensENSP0000036457877.105365.5263erpetoichthys_calabaricusENSECRP0000000530381.388969.1667
ENSG00000204356homo_sapiensENSP0000036457873.947463.9474kryptolebias_marmoratusENSKMAP0000000316674.338664.2857
ENSG00000204356homo_sapiensENSP0000036457875.526364.2105salvator_merianaeENSSMRP0000002137770.343159.8039
ENSG00000204356homo_sapiensENSP000003645787061.3158oryzias_javanicusENSOJAP0000000363476.436866.954
ENSG00000204356homo_sapiensENSP000003645787060.2632amphilophus_citrinellusENSACIP0000002163878.235367.3529
ENSG00000204356homo_sapiensENSP0000036457875.789564.4737dicentrarchus_labraxENSDLAP0000506994177.837866.2162
ENSG00000204356homo_sapiensENSP0000036457874.210565amphiprion_perculaENSAPEP0000000160081.034570.977
ENSG00000204356homo_sapiensENSP0000036457876.578966.8421oryzias_sinensisENSOSIP0000000694481.741671.3483
ENSG00000204356homo_sapiensENSP0000036457872.894764.7368gopherus_evgoodeiENSGEVP0000502843886.292876.6355
ENSG00000204356homo_sapiensENSP0000036457850.526342.1053chelonoidis_abingdoniiENSCABP0000003153564.646553.8721
ENSG00000204356homo_sapiensENSP0000036457876.052665.5263seriola_dumeriliENSSDUP0000002775180.277869.1667
ENSG00000204356homo_sapiensENSP0000036457873.684261.3158cottoperca_gobioENSCGOP0000001091369.478957.8164
ENSG00000204356homo_sapiensENSP0000036457875.789563.6842gasterosteus_aculeatusENSGACP0000000384579.778467.036
ENSG00000204356homo_sapiensENSP0000036457871.052661.0526cynoglossus_semilaevisENSCSEP0000001768379.411868.2353
ENSG00000204356homo_sapiensENSP0000036457875.526365.2632poecilia_formosaENSPFOP0000000297080.392269.4678
ENSG00000204356homo_sapiensENSP0000036457876.052667.1053myripristis_murdjanENSMMDP0000500913578.532669.2935
ENSG00000204356homo_sapiensENSP0000036457873.947461.8421sander_luciopercaENSSLUP0000003772179.154966.1972
ENSG00000204356homo_sapiensENSP0000036457870.789561.5789strigops_habroptilaENSSHBP0000500744086.217975
ENSG00000204356homo_sapiensENSP0000036457876.578966.8421amphiprion_ocellarisENSAOCP0000001275180.833370.5556
ENSG00000204356homo_sapiensENSP0000036457874.736865.7895terrapene_carolina_triunguisENSTMTP0000002205587.384676.9231
ENSG00000204356homo_sapiensENSP0000036457873.421160.2632hucho_huchoENSHHUP0000005318266.587154.6539
ENSG00000204356homo_sapiensENSP0000036457865.789552.6316hucho_huchoENSHHUP0000004463261.728449.3827
ENSG00000204356homo_sapiensENSP0000036457873.421162.8947betta_splendensENSBSLP0000002464577.715966.5738
ENSG00000204356homo_sapiensENSP0000036457876.578965.5263pygocentrus_nattereriENSPNAP0000000564277.807566.5775
ENSG00000204356homo_sapiensENSP0000036457876.315866.5789anabas_testudineusENSATEP0000003993971.428662.3153
ENSG00000204356homo_sapiensENSP0000036457838.947424.2105ciona_savignyiENSCSAVP0000000707953.818233.4545
ENSG00000204356homo_sapiensENSP0000036457872.105361.5789seriola_lalandi_dorsalisENSSLDP0000003179479.651268.0233
ENSG00000204356homo_sapiensENSP0000036457876.578965labrus_bergyltaENSLBEP0000001711179.076167.1196
ENSG00000204356homo_sapiensENSP0000036457874.736863.9474pundamilia_nyerereiENSPNYP0000002359581.142969.4286
ENSG00000204356homo_sapiensENSP0000036457873.421163.4211mastacembelus_armatusENSMAMP0000000446574.464.2667
ENSG00000204356homo_sapiensENSP0000036457876.052665.7895stegastes_partitusENSSPAP0000001716563.938155.3097
ENSG00000204356homo_sapiensENSP0000036457872.894760.2632oncorhynchus_tshawytschaENSOTSP0000506732077.80964.3258
ENSG00000204356homo_sapiensENSP0000036457869.210556.8421oncorhynchus_tshawytschaENSOTSP0000502543372.651959.6685
ENSG00000204356homo_sapiensENSP0000036457876.052666.3158acanthochromis_polyacanthusENSAPOP0000000643081.179870.7865
ENSG00000204356homo_sapiensENSP0000036457854.736845.5263aquila_chrysaetos_chrysaetosENSACCP0002002081162.089651.6418
ENSG00000204356homo_sapiensENSP0000036457873.157963.9474nothobranchius_furzeriENSNFUP0001504047272.774963.6126
ENSG00000204356homo_sapiensENSP0000036457873.684264.4737cyprinodon_variegatusENSCVAP0000002120680.229270.2006
ENSG00000204356homo_sapiensENSP0000036457868.157957.1053denticeps_clupeoidesENSDCDP0000002544974.639862.536
ENSG00000204356homo_sapiensENSP0000036457875.263264.7368larimichthys_croceaENSLCRP0000502013675.661465.0794
ENSG00000204356homo_sapiensENSP0000036457850.526343.1579takifugu_rubripesENSTRUP0000008286579.338867.7686
ENSG00000204356homo_sapiensENSP000003645787056.8421hippocampus_comesENSHCOP0000000545165.196152.9412
ENSG00000204356homo_sapiensENSP000003645787562.1053cyprinus_carpio_carpioENSCCRP0000002518778.082264.6575
ENSG00000204356homo_sapiensENSP0000036457875.789564.2105poecilia_latipinnaENSPLAP0000001445878.688566.6667
ENSG00000204356homo_sapiensENSP0000036457842.368434.4737sinocyclocheilus_grahamiENSSGRP0000004620482.564167.1795
ENSG00000204356homo_sapiensENSP0000036457871.052658.9474sinocyclocheilus_grahamiENSSGRP000000236377562.2222
ENSG00000204356homo_sapiensENSP0000036457876.052664.7368maylandia_zebraENSMZEP0000503534080.726368.7151
ENSG00000204356homo_sapiensENSP0000036457823.421120.2632tetraodon_nigroviridisENSTNIP0000002310080.180269.3694
ENSG00000204356homo_sapiensENSP000003645787060.7895paramormyrops_kingsleyaeENSPKIP0000003166171.12361.7647
ENSG00000204356homo_sapiensENSP0000036457876.315865.2632scleropages_formosusENSSFOP0001502652978.590867.2087
ENSG00000204356homo_sapiensENSP0000036457871.052660.5263leptobrachium_leishanenseENSLLEP0000001947978.488466.8605
ENSG00000204356homo_sapiensENSP0000036457877.105366.3158scophthalmus_maximusENSSMAP0000003291980.494569.2308
ENSG00000204356homo_sapiensENSP0000036457876.315865.7895oryzias_melastigmaENSOMEP0000000748266.974657.7367

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0000785part_of chromatin1IDAHomo_sapiens(9606)Component
GO:0003682enables chromatin binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding3HDA,IDA,NASHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus3IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IDAHomo_sapiens(9606)Component
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0032021part_of NELF complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0034244involved_in negative regulation of transcription elongation by RNA polymerase II2IBA,IDAHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0051179involved_in localization1IDAHomo_sapiens(9606)Process
GO:0051571involved_in positive regulation of histone H3-K4 methylation1IEAHomo_sapiens(9606)Process
GO:0070374involved_in positive regulation of ERK1 and ERK2 cascade1IEAHomo_sapiens(9606)Process

Expression