Ensembl ID ENSG00000204356 Gene ID 7936 Accession 13974
Gene Symbol NELFE Alias RD;RDP;RDBP;D6S45;NELF-E Full Name negative elongation factor complex member E
Position 6 : 31952087 - 31958971 Length 6885 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]

ENSG00000204356 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000204356 NELFE 0.41 8.64e-13 BRCA
ENSG00000204356 NELFE 1.33 7.76e-33 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000204356 NELFE liver tumors 12079511
ENSG00000204356 NELFE gastric cancer 16452188
ENSG00000204356 NELFE lung tumors 24954872
ENSG00000204356 NELFE malignant tumours 28327598
ENSG00000204356 NELFE tumor 28697339
ENSG00000204356 NELFE tumors 30833661
ENSG00000204356 NELFE tumor 31638184
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000204356 NELFE MESO 0.05 high
ENSG00000204356 NELFE SARC 0.0021 high
ENSG00000204356 NELFE STAD 0.035 high
ENSG00000204356 NELFE UVM 0.016 low
ENSG00000204356 NELFE UCEC 0.011 high
ENSG00000204356 NELFE LGG 0.0023 low
ENSG00000204356 NELFE HNSC 0.041 high
ENSG00000204356 NELFE READ 0.00077 low
ENSG00000204356 NELFE KICH 0.00014 high
ENSG00000204356 NELFE LUAD 0.041 high
ENSG00000204356 NELFE THYM 0.01 low
ENSG00000204356 NELFE COAD 0.018 high
ENSG00000204356 NELFE OV 0.0071 low
ENSG00000204356 NELFE DLBC 0.034 low
ENSG00000204356 NELFE KIRC 0.001 high
ENSG00000204356 NELFE BLCA 0.043 high
ENSG00000204356 NELFE LIHC 0.01 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000204356 NELFE DLBC Del 1.473551 0.166909 0.534071 0.125000
ENSG00000204356 NELFE UVM Amp 1.976306 0.243776 1.147565 0.537500