RBP Type	Non-canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000197894	Gene ID	128	Accession	253
Symbol	ADH5	Alias	FDH;ADHX;ADH-3;AMEDS;BMFS7;FALDH;GSNOR;GSH-FDH;HEL-S-60p	Full Name	alcohol dehydrogenase 5 (class III), chi polypeptide
Status	Confidence	Length	17811 bases	Strand	Minus strand
Position	4 : 99070978 - 99088788	RNA binding domain	N.A.
Summary	This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]