RBP Type	Non-canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	Stress granule or P-body
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000196961	Gene ID	160	Accession	561
Symbol	AP2A1	Alias	ADTAA;CLAPA1;AP2-ALPHA	Full Name	adaptor related protein complex 2 subunit alpha 1
Status	Confidence	Length	40114 bases	Strand	Plus strand
Position	19 : 49767001 - 49807114	RNA binding domain	N.A.
Summary	This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]