RBP Type
Canonical_RBPs
Diseases
Cancer Disease
Drug
Drug
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000188641 Gene ID
1806
Accession
3012
Symbol
DPYD
Alias
DHP;DPD;DYPD;DHPDHASE
Full Name
dihydropyrimidine dehydrogenase
Status
Confidence
Length
843307 bases
Strand
Minus strand
Position
1 : 97077743 - 97921049
RNA binding domain
Dus
Summary
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000359211
Dus
PF01207
1e-06
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
31363108
A bioinformatic analysis identifies circadian expression of splicing factors and time-dependent alternative splicing events in the HD-MY-Z cell line.
Nikolai Genov
2019-07-30
Scientific reports
24401318
microRNAs miR-27a and miR-27b directly regulate liver dihydropyrimidine dehydrogenase expression through two conserved binding sites.
M Steven Offer
2014-03-01
Molecular cancer therapeutics
Name
Transcript ID
bp
Protein
Translation ID
DPYD-202
ENST00000370192
4423
1025aa
ENSP00000359211
DPYD-204
ENST00000474241
1036
No protein
-
DPYD-201
ENST00000306031
1779
173aa
ENSP00000307107
DPYD-203
ENST00000460019
551
No protein
-
DPYD-205
ENST00000646851
799
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
850 Body Mass Index 3.82174696255354E-5 17903300 914 Body Mass Index 9.34491536301856E-5 17903300 1052 Body Mass Index 3.90550385800621E-5 17903300 1077 Body Weight 7.75007406653866E-5 17903300 1531 Body Mass Index 4.07827249701877E-5 17903300 1549 Body Mass Index 1.49787933724885E-5 17903300 1814 Body Mass Index 5.60146183386526E-5 17903300 4033 Triglycerides 5.77060579256276E-5 17903299 4277 Lipids 2.82665825673754E-5 17903299 6646 Platelet Aggregation 2.88852579640401E-5 17903294 6659 Platelet Aggregation 2.76089868100783E-5 17903294 6664 Platelet Aggregation 1.6432518722821E-5 17903294 6665 Platelet Aggregation 2.76296082390217E-5 17903294 21747 Social Behavior 5.382e-005 - 21845 Personality 9.78e-005 - 21846 Personality 9.78e-005 - 27353 Hypertrophy, Left Ventricular 4.0790000E-005 - 27398 Hypertrophy, Left Ventricular 3.5040000E-005 - 37130 Platelet Function Tests 3.3800000E-006 - 39219 Platelet Function Tests 6.2500000E-006 - 39220 Platelet Function Tests 6.2500000E-006 - 39221 Platelet Function Tests 6.2500000E-006 - 39222 Platelet Function Tests 6.2500000E-006 - 39468 Platelet Function Tests 1.2672500E-005 - 41306 Platelet Function Tests 3.3097800E-005 - 41370 Platelet Function Tests 3.7177700E-005 - 41375 Platelet Function Tests 3.0147777E-006 - 74440 Platelet Count 9E-6 21507922 77706 Menarche 2E-9 25231870 79805 Schizophrenia 1E-7 26198764
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000188641 homo_sapiens ENSP00000219240 46.3291 26.8354 homo_sapiens ENSP00000359211 17.8537 10.3415 ENSG00000188641 homo_sapiens ENSP00000293195 29.9389 15.8859 homo_sapiens ENSP00000359211 14.3415 7.60976
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000188641 homo_sapiens ENSP00000359211 99.6098 99.1219 nomascus_leucogenys ENSNLEP00000013841 99.6098 99.1219 ENSG00000188641 homo_sapiens ENSP00000359211 99.7073 99.7073 pan_paniscus ENSPPAP00000038331 99.7073 99.7073 ENSG00000188641 homo_sapiens ENSP00000359211 99.3171 98.9268 pongo_abelii ENSPPYP00000001308 99.3171 98.9268 ENSG00000188641 homo_sapiens ENSP00000359211 99.7073 99.7073 pan_troglodytes ENSPTRP00000001697 99.7073 99.7073 ENSG00000188641 homo_sapiens ENSP00000359211 40.9756 40.0976 gorilla_gorilla ENSGGOP00000021585 95.4545 93.4091 ENSG00000188641 homo_sapiens ENSP00000359211 16.4878 16.3902 gorilla_gorilla ENSGGOP00000037543 97.6879 97.1098 ENSG00000188641 homo_sapiens ENSP00000359211 95.0244 88.6829 ornithorhynchus_anatinus ENSOANP00000007378 95.0244 88.6829 ENSG00000188641 homo_sapiens ENSP00000359211 94.8293 87.9024 sarcophilus_harrisii ENSSHAP00000020007 94.8293 87.9024 ENSG00000188641 homo_sapiens ENSP00000359211 63.2195 59.122 notamacropus_eugenii ENSMEUP00000011308 66.8731 62.5387 ENSG00000188641 homo_sapiens ENSP00000359211 77.8537 74.439 choloepus_hoffmanni ENSCHOP00000009517 78.0822 74.6575 ENSG00000188641 homo_sapiens ENSP00000359211 9.46341 9.07317 dasypus_novemcinctus ENSDNOP00000025117 95.098 91.1765 ENSG00000188641 homo_sapiens ENSP00000359211 82.0488 79.2195 erinaceus_europaeus ENSEEUP00000003071 82.0488 79.2195 ENSG00000188641 homo_sapiens ENSP00000359211 89.1707 84.7805 echinops_telfairi ENSETEP00000004367 89.3451 84.9462 ENSG00000188641 homo_sapiens ENSP00000359211 98.1463 97.2683 callithrix_jacchus ENSCJAP00000080369 98.1463 97.2683 ENSG00000188641 homo_sapiens ENSP00000359211 98.9268 97.7561 cercocebus_atys ENSCATP00000019994 97.971 96.8116 ENSG00000188641 homo_sapiens ENSP00000359211 99.2195 98.2439 macaca_fascicularis ENSMFAP00000047710 85.8228 84.9789 ENSG00000188641 homo_sapiens ENSP00000359211 98.439 97.2683 macaca_mulatta ENSMMUP00000027278 97.5822 96.4217 ENSG00000188641 homo_sapiens ENSP00000359211 99.4146 98.439 macaca_nemestrina ENSMNEP00000009049 99.4146 98.439 ENSG00000188641 homo_sapiens ENSP00000359211 99.3171 98.6341 papio_anubis ENSPANP00000047629 97.4163 96.7464 ENSG00000188641 homo_sapiens ENSP00000359211 99.4146 98.6341 mandrillus_leucophaeus ENSMLEP00000015580 99.4146 98.6341 ENSG00000188641 homo_sapiens ENSP00000359211 91.2195 88 tursiops_truncatus ENSTTRP00000008492 91.3086 88.0859 ENSG00000188641 homo_sapiens ENSP00000359211 93.7561 90.1463 vulpes_vulpes ENSVVUP00000029939 96.1 92.4 ENSG00000188641 homo_sapiens ENSP00000359211 94.9268 89.561 mus_spretus MGP_SPRETEiJ_P0062584 94.9268 89.561 ENSG00000188641 homo_sapiens ENSP00000359211 96.8781 93.4634 equus_asinus ENSEASP00005023077 96.8781 93.4634 ENSG00000188641 homo_sapiens ENSP00000359211 96.4878 92.7805 capra_hircus ENSCHIP00000015652 95.7406 92.062 ENSG00000188641 homo_sapiens ENSP00000359211 97.2683 93.7561 loxodonta_africana ENSLAFP00000001505 97.2683 93.7561 ENSG00000188641 homo_sapiens ENSP00000359211 96.6829 93.2683 panthera_leo ENSPLOP00000006809 96.5887 93.1774 ENSG00000188641 homo_sapiens ENSP00000359211 87.9024 84.6829 ailuropoda_melanoleuca ENSAMEP00000017600 96.7777 93.2331 ENSG00000188641 homo_sapiens ENSP00000359211 96.6829 92.7805 bos_indicus_hybrid ENSBIXP00005003078 93.5788 89.8017 ENSG00000188641 homo_sapiens ENSP00000359211 96.4878 92.6829 oryctolagus_cuniculus ENSOCUP00000043311 95.2794 91.5222 ENSG00000188641 homo_sapiens ENSP00000359211 96.7805 93.2683 equus_caballus ENSECAP00000063482 95.2015 91.7466 ENSG00000188641 homo_sapiens ENSP00000359211 96.2927 92.3902 canis_lupus_familiaris ENSCAFP00845019969 93.5545 89.763 ENSG00000188641 homo_sapiens ENSP00000359211 96.6829 93.1707 panthera_pardus ENSPPRP00000002465 96.5887 93.0799 ENSG00000188641 homo_sapiens ENSP00000359211 91.3171 88.7805 marmota_marmota_marmota ENSMMMP00000027457 96.9948 94.3005 ENSG00000188641 homo_sapiens ENSP00000359211 15.5122 14.9268 balaenoptera_musculus ENSBMSP00010002841 87.8453 84.5304 ENSG00000188641 homo_sapiens ENSP00000359211 95.7073 92.1951 cavia_porcellus ENSCPOP00000003404 95.7073 92.1951 ENSG00000188641 homo_sapiens ENSP00000359211 96.9756 93.1707 felis_catus ENSFCAP00000034474 96.8811 93.0799 ENSG00000188641 homo_sapiens ENSP00000359211 14.8293 14.5366 ursus_americanus ENSUAMP00000018500 91.5663 89.759 ENSG00000188641 homo_sapiens ENSP00000359211 94.7317 88.1951 monodelphis_domestica ENSMODP00000005005 94.7317 88.1951 ENSG00000188641 homo_sapiens ENSP00000359211 14.8293 14.3415 bison_bison_bison ENSBBBP00000000109 89.9408 86.9822 ENSG00000188641 homo_sapiens ENSP00000359211 96.4878 93.2683 monodon_monoceros ENSMMNP00015010434 96.4878 93.2683 ENSG00000188641 homo_sapiens ENSP00000359211 96.4878 92.6829 sus_scrofa ENSSSCP00000007333 96.4878 92.6829 ENSG00000188641 homo_sapiens ENSP00000359211 98.0488 95.5122 microcebus_murinus ENSMICP00000024009 98.0488 95.5122 ENSG00000188641 homo_sapiens ENSP00000359211 95.3171 90.9268 octodon_degus ENSODEP00000008092 95.3171 90.9268 ENSG00000188641 homo_sapiens ENSP00000359211 15.8049 15.3171 jaculus_jaculus ENSJJAP00000021678 89.011 86.2637 ENSG00000188641 homo_sapiens ENSP00000359211 96.3902 92.6829 ovis_aries_rambouillet ENSOARP00020001523 96.2963 92.5926 ENSG00000188641 homo_sapiens ENSP00000359211 89.561 86.0488 ursus_maritimus ENSUMAP00000011896 96.6316 92.8421 ENSG00000188641 homo_sapiens ENSP00000359211 57.8537 55.2195 ochotona_princeps ENSOPRP00000000445 60.8205 58.0513 ENSG00000188641 homo_sapiens ENSP00000359211 96.4878 93.2683 delphinapterus_leucas ENSDLEP00000016942 96.4878 93.2683 ENSG00000188641 homo_sapiens ENSP00000359211 96.5854 93.3659 physeter_catodon ENSPCTP00005002884 96.5854 93.3659 ENSG00000188641 homo_sapiens ENSP00000359211 94.6341 89.4634 mus_caroli MGP_CAROLIEiJ_P0060192 94.6341 89.4634 ENSG00000188641 homo_sapiens ENSP00000359211 94.9268 89.561 mus_musculus ENSMUSP00000039429 94.9268 89.561 ENSG00000188641 homo_sapiens ENSP00000359211 96.5854 91.0244 dipodomys_ordii ENSDORP00000021258 96.5854 91.0244 ENSG00000188641 homo_sapiens ENSP00000359211 96.1951 92 mustela_putorius_furo ENSMPUP00000003246 96.1014 91.9103 ENSG00000188641 homo_sapiens ENSP00000359211 98.3415 97.1707 aotus_nancymaae ENSANAP00000038596 98.3415 97.1707 ENSG00000188641 homo_sapiens ENSP00000359211 90.7317 89.7561 saimiri_boliviensis_boliviensis ENSSBOP00000006401 97.5866 96.5373 ENSG00000188641 homo_sapiens ENSP00000359211 89.4634 86.1463 vicugna_pacos ENSVPAP00000001011 90.6126 87.253 ENSG00000188641 homo_sapiens ENSP00000359211 99.2195 98.1463 chlorocebus_sabaeus ENSCSAP00000016531 99.2195 98.1463 ENSG00000188641 homo_sapiens ENSP00000359211 87.7073 84.5854 tupaia_belangeri ENSTBEP00000014155 89.0099 85.8416 ENSG00000188641 homo_sapiens ENSP00000359211 89.0732 83.3171 mesocricetus_auratus ENSMAUP00000018295 90.3066 84.4708 ENSG00000188641 homo_sapiens ENSP00000359211 96.6829 93.0732 phocoena_sinus ENSPSNP00000026994 96.6829 93.0732 ENSG00000188641 homo_sapiens ENSP00000359211 89.2683 85.9512 camelus_dromedarius ENSCDRP00005001600 96.4173 92.8346 ENSG00000188641 homo_sapiens ENSP00000359211 74.2439 70.0488 carlito_syrichta ENSTSYP00000018495 91.3565 86.1945 ENSG00000188641 homo_sapiens ENSP00000359211 16.0976 15.8049 panthera_tigris_altaica ENSPTIP00000016676 95.9302 94.186 ENSG00000188641 homo_sapiens ENSP00000359211 94.7317 89.561 rattus_norvegicus ENSRNOP00000072507 94.7317 89.561 ENSG00000188641 homo_sapiens ENSP00000359211 97.9512 95.4146 prolemur_simus ENSPSMP00000037967 97.9512 95.4146 ENSG00000188641 homo_sapiens ENSP00000359211 95.7073 91.4146 microtus_ochrogaster ENSMOCP00000022666 95.7073 91.4146 ENSG00000188641 homo_sapiens ENSP00000359211 89.6585 86.0488 sorex_araneus ENSSARP00000009902 89.6585 86.0488 ENSG00000188641 homo_sapiens ENSP00000359211 94.8293 90.7317 peromyscus_maniculatus_bairdii ENSPEMP00000011913 94.8293 90.7317 ENSG00000188641 homo_sapiens ENSP00000359211 96.6829 92.5854 bos_mutus ENSBMUP00000004506 96.6829 92.5854 ENSG00000188641 homo_sapiens ENSP00000359211 15.2195 14.5366 mus_spicilegus ENSMSIP00000015960 94.5455 90.303 ENSG00000188641 homo_sapiens ENSP00000359211 71.2195 66.1463 mus_spicilegus ENSMSIP00000021404 90.6832 84.2236 ENSG00000188641 homo_sapiens ENSP00000359211 94.2439 90.9268 pteropus_vampyrus ENSPVAP00000000307 95.6436 92.2772 ENSG00000188641 homo_sapiens ENSP00000359211 35.8049 34.6341 myotis_lucifugus ENSMLUP00000018276 97.6064 94.4149 ENSG00000188641 homo_sapiens ENSP00000359211 94.1463 87.6098 vombatus_ursinus ENSVURP00010001029 94.1463 87.6098 ENSG00000188641 homo_sapiens ENSP00000359211 97.1707 93.4634 rhinolophus_ferrumequinum ENSRFEP00010018208 97.2656 93.5547 ENSG00000188641 homo_sapiens ENSP00000359211 92.6829 88.6829 neovison_vison ENSNVIP00000025162 96.0566 91.911 ENSG00000188641 homo_sapiens ENSP00000359211 96.6829 92.5854 bos_taurus ENSBTAP00000007139 96.6829 92.5854 ENSG00000188641 homo_sapiens ENSP00000359211 25.561 24.5854 heterocephalus_glaber_female ENSHGLP00000001452 92.5795 89.0459 ENSG00000188641 homo_sapiens ENSP00000359211 95.2195 94.0488 rhinopithecus_bieti ENSRBIP00000022456 97.992 96.7871 ENSG00000188641 homo_sapiens ENSP00000359211 96.2927 92.4878 canis_lupus_dingo ENSCAFP00020014600 96.1988 92.3977 ENSG00000188641 homo_sapiens ENSP00000359211 96.5854 93.8537 sciurus_vulgaris ENSSVLP00005001783 96.5854 93.8537 ENSG00000188641 homo_sapiens ENSP00000359211 94.3415 87.5122 phascolarctos_cinereus ENSPCIP00000029767 94.3415 87.5122 ENSG00000188641 homo_sapiens ENSP00000359211 79.8049 76.2927 procavia_capensis ENSPCAP00000000982 84.5915 80.8687 ENSG00000188641 homo_sapiens ENSP00000359211 95.3171 90.1463 nannospalax_galili ENSNGAP00000007307 95.3171 90.1463 ENSG00000188641 homo_sapiens ENSP00000359211 96.6829 92.5854 bos_grunniens ENSBGRP00000009138 96.6829 92.5854 ENSG00000188641 homo_sapiens ENSP00000359211 94.8293 90.3415 chinchilla_lanigera ENSCLAP00000014238 96.0474 91.502 ENSG00000188641 homo_sapiens ENSP00000359211 96.9756 92.8781 cervus_hanglu_yarkandensis ENSCHYP00000023749 96.9756 92.8781 ENSG00000188641 homo_sapiens ENSP00000359211 96.9756 93.3659 catagonus_wagneri ENSCWAP00000006400 96.9756 93.3659 ENSG00000188641 homo_sapiens ENSP00000359211 91.4146 88.7805 ictidomys_tridecemlineatus ENSSTOP00000007560 96.4985 93.7178 ENSG00000188641 homo_sapiens ENSP00000359211 97.7561 94.7317 otolemur_garnettii ENSOGAP00000000148 97.7561 94.7317 ENSG00000188641 homo_sapiens ENSP00000359211 94.3415 92.8781 cebus_imitator ENSCCAP00000000698 97.0884 95.5823 ENSG00000188641 homo_sapiens ENSP00000359211 96.7805 94.1463 urocitellus_parryii ENSUPAP00010000396 94.4762 91.9048 ENSG00000188641 homo_sapiens ENSP00000359211 97.2683 93.2683 moschus_moschiferus ENSMMSP00000023697 97.2683 93.2683 ENSG00000188641 homo_sapiens ENSP00000359211 50.2439 49.6585 rhinopithecus_roxellana ENSRROP00000015267 99.6132 98.4526 ENSG00000188641 homo_sapiens ENSP00000359211 94.7317 89.1707 mus_pahari MGP_PahariEiJ_P0071129 94.7317 89.1707 ENSG00000188641 homo_sapiens ENSP00000359211 86.439 83.9024 propithecus_coquereli ENSPCOP00000001049 97.1491 94.2982 ENSG00000188641 homo_sapiens ENSP00000359211 78.439 65.561 caenorhabditis_elegans C25F6.3.1 75.9207 63.4561 ENSG00000188641 homo_sapiens ENSP00000359211 76.8781 65.7561 drosophila_melanogaster FBpp0071273 76.4306 65.3734 ENSG00000188641 homo_sapiens ENSP00000359211 83.4146 71.3171 ciona_intestinalis ENSCINP00000007792 83.4961 71.3867 ENSG00000188641 homo_sapiens ENSP00000359211 8.58537 6.73171 petromyzon_marinus ENSPMAP00000008183 81.4815 63.8889 ENSG00000188641 homo_sapiens ENSP00000359211 79.5122 65.4634 eptatretus_burgeri ENSEBUP00000025321 78.744 64.8309 ENSG00000188641 homo_sapiens ENSP00000359211 87.7073 77.3659 callorhinchus_milii ENSCMIP00000009829 87.7073 77.3659 ENSG00000188641 homo_sapiens ENSP00000359211 28.1951 25.1707 latimeria_chalumnae ENSLACP00000012665 86.7868 77.4775 ENSG00000188641 homo_sapiens ENSP00000359211 12.6829 10.6341 latimeria_chalumnae ENSLACP00000007431 86.0927 72.1854 ENSG00000188641 homo_sapiens ENSP00000359211 90.1463 79.4146 lepisosteus_oculatus ENSLOCP00000010028 90.1463 79.4146 ENSG00000188641 homo_sapiens ENSP00000359211 88 77.3659 clupea_harengus ENSCHAP00000020831 87.234 76.6925 ENSG00000188641 homo_sapiens ENSP00000359211 85.2683 72.8781 clupea_harengus ENSCHAP00000053217 81.9887 70.0751 ENSG00000188641 homo_sapiens ENSP00000359211 86.3415 76.2927 danio_rerio ENSDARP00000108791 86.5949 76.5166 ENSG00000188641 homo_sapiens ENSP00000359211 60 52.0976 danio_rerio ENSDARP00000141769 87.4822 75.9602 ENSG00000188641 homo_sapiens ENSP00000359211 87.3171 76.1951 carassius_auratus ENSCARP00000088011 84.434 73.6792 ENSG00000188641 homo_sapiens ENSP00000359211 85.9512 75.8049 carassius_auratus ENSCARP00000060855 83.0349 73.2328 ENSG00000188641 homo_sapiens ENSP00000359211 17.7561 15.122 carassius_auratus ENSCARP00000008620 75.5187 64.3154 ENSG00000188641 homo_sapiens ENSP00000359211 20.0976 16.1951 carassius_auratus ENSCARP00000100056 69.8305 56.2712 ENSG00000188641 homo_sapiens ENSP00000359211 88.5854 78.5366 astyanax_mexicanus ENSAMXP00000027520 85.8223 76.087 ENSG00000188641 homo_sapiens ENSP00000359211 87.9024 77.561 ictalurus_punctatus ENSIPUP00000013740 87.8168 77.4854 ENSG00000188641 homo_sapiens ENSP00000359211 88.2927 76.3902 esox_lucius ENSELUP00000026606 86.4374 74.7851 ENSG00000188641 homo_sapiens ENSP00000359211 83.8049 71.9024 electrophorus_electricus ENSEEEP00000024113 79.39 68.1146 ENSG00000188641 homo_sapiens ENSP00000359211 87.1219 76 oncorhynchus_kisutch ENSOKIP00005057514 87.207 76.0742 ENSG00000188641 homo_sapiens ENSP00000359211 88.9756 76.5854 oncorhynchus_kisutch ENSOKIP00005095502 88.716 76.3619 ENSG00000188641 homo_sapiens ENSP00000359211 87.0244 75.7073 oncorhynchus_mykiss ENSOMYP00000137413 87.0244 75.7073 ENSG00000188641 homo_sapiens ENSP00000359211 88.9756 76.5854 oncorhynchus_mykiss ENSOMYP00000045801 88.716 76.3619 ENSG00000188641 homo_sapiens ENSP00000359211 52.6829 42.2439 salmo_salar ENSSSAP00000022035 70.4961 56.5274 ENSG00000188641 homo_sapiens ENSP00000359211 88.2927 75.9024 salmo_salar ENSSSAP00000084208 84.5005 72.6424 ENSG00000188641 homo_sapiens ENSP00000359211 84.8781 73.7561 salmo_salar ENSSSAP00000060569 84.3023 73.2558 ENSG00000188641 homo_sapiens ENSP00000359211 86.6341 75.7073 salmo_trutta ENSSTUP00000073029 86.6341 75.7073 ENSG00000188641 homo_sapiens ENSP00000359211 88.3902 76 salmo_trutta ENSSTUP00000017451 87.5362 75.2657 ENSG00000188641 homo_sapiens ENSP00000359211 86.3415 74.3415 gadus_morhua ENSGMOP00000032261 86.3415 74.3415 ENSG00000188641 homo_sapiens ENSP00000359211 88.0976 77.0732 fundulus_heteroclitus ENSFHEP00000000609 88.1836 77.1484 ENSG00000188641 homo_sapiens ENSP00000359211 86.8293 76 poecilia_reticulata ENSPREP00000021733 86.8293 76 ENSG00000188641 homo_sapiens ENSP00000359211 86.7317 75.9024 xiphophorus_maculatus ENSXMAP00000018704 86.6472 75.8285 ENSG00000188641 homo_sapiens ENSP00000359211 87.2195 76.3902 oryzias_latipes ENSORLP00000017096 87.5612 76.6895 ENSG00000188641 homo_sapiens ENSP00000359211 84.2927 73.7561 cyclopterus_lumpus ENSCLMP00005036488 86.747 75.9036 ENSG00000188641 homo_sapiens ENSP00000359211 86.5366 74.8293 oreochromis_niloticus ENSONIP00000039823 86.8756 75.1224 ENSG00000188641 homo_sapiens ENSP00000359211 83.2195 71.9024 haplochromis_burtoni ENSHBUP00000017238 86.4235 74.6707 ENSG00000188641 homo_sapiens ENSP00000359211 84 72.6829 astatotilapia_calliptera ENSACLP00000002716 86.3591 74.7242 ENSG00000188641 homo_sapiens ENSP00000359211 87.2195 75.8049 sparus_aurata ENSSAUP00010017328 87.6471 76.1765 ENSG00000188641 homo_sapiens ENSP00000359211 87.6098 76.4878 lates_calcarifer ENSLCAP00010034146 87.6098 76.4878 ENSG00000188641 homo_sapiens ENSP00000359211 89.6585 81.561 xenopus_tropicalis ENSXETP00000074610 89.3969 81.323 ENSG00000188641 homo_sapiens ENSP00000359211 56 49.9512 chrysemys_picta_bellii ENSCPBP00000015459 88.4438 78.8906 ENSG00000188641 homo_sapiens ENSP00000359211 14.5366 13.6585 chrysemys_picta_bellii ENSCPBP00000038792 87.6471 82.3529 ENSG00000188641 homo_sapiens ENSP00000359211 38.8293 36.1951 sphenodon_punctatus ENSSPUP00000010340 92.3434 86.0789 ENSG00000188641 homo_sapiens ENSP00000359211 15.0244 14.0488 sphenodon_punctatus ENSSPUP00000010181 87.5 81.8182 ENSG00000188641 homo_sapiens ENSP00000359211 93.0732 86.0488 crocodylus_porosus ENSCPRP00005021253 93.0732 86.0488 ENSG00000188641 homo_sapiens ENSP00000359211 88.2927 78.7317 notechis_scutatus ENSNSUP00000027908 89.6928 79.9802 ENSG00000188641 homo_sapiens ENSP00000359211 88.3902 78.5366 pseudonaja_textilis ENSPTXP00000006393 90.1493 80.0995 ENSG00000188641 homo_sapiens ENSP00000359211 93.0732 85.2683 anas_platyrhynchos_platyrhynchos ENSAPLP00000011867 93.1641 85.3516 ENSG00000188641 homo_sapiens ENSP00000359211 91.8049 84.6829 gallus_gallus ENSGALP00010036012 91.1822 84.1085 ENSG00000188641 homo_sapiens ENSP00000359211 92.1951 84.8781 serinus_canaria ENSSCAP00000017151 92.2852 84.9609 ENSG00000188641 homo_sapiens ENSP00000359211 92.5854 84.7805 parus_major ENSPMJP00000026466 92.5854 84.7805 ENSG00000188641 homo_sapiens ENSP00000359211 92.3902 84.2927 anolis_carolinensis ENSACAP00000005445 92.5709 84.4575 ENSG00000188641 homo_sapiens ENSP00000359211 19.7073 17.8537 neolamprologus_brichardi ENSNBRP00000002185 88.2096 79.9127 ENSG00000188641 homo_sapiens ENSP00000359211 53.9512 47.4146 neolamprologus_brichardi ENSNBRP00000002173 90.6557 79.6721 ENSG00000188641 homo_sapiens ENSP00000359211 87.8049 78.6341 naja_naja ENSNNAP00000003097 88.3219 79.0972 ENSG00000188641 homo_sapiens ENSP00000359211 92.7805 84.8781 podarcis_muralis ENSPMRP00000021587 86.5332 79.1629 ENSG00000188641 homo_sapiens ENSP00000359211 86.0488 79.1219 geospiza_fortis ENSGFOP00000011185 92.9399 85.4584 ENSG00000188641 homo_sapiens ENSP00000359211 91.5122 83.5122 taeniopygia_guttata ENSTGUP00000005710 92.2321 84.1691 ENSG00000188641 homo_sapiens ENSP00000359211 87.5122 76.3902 erpetoichthys_calabaricus ENSECRP00000024411 87.5977 76.4648 ENSG00000188641 homo_sapiens ENSP00000359211 87.5122 76 kryptolebias_marmoratus ENSKMAP00000012788 87.7691 76.2231 ENSG00000188641 homo_sapiens ENSP00000359211 92.3902 83.6098 salvator_merianae ENSSMRP00000023255 92.3002 83.5283 ENSG00000188641 homo_sapiens ENSP00000359211 84.8781 73.8537 amphilophus_citrinellus ENSACIP00000001652 85.7988 74.6548 ENSG00000188641 homo_sapiens ENSP00000359211 87.1219 75.6098 dicentrarchus_labrax ENSDLAP00005001138 87.1219 75.6098 ENSG00000188641 homo_sapiens ENSP00000359211 87.7073 76.0976 amphiprion_percula ENSAPEP00000014793 87.6218 76.0234 ENSG00000188641 homo_sapiens ENSP00000359211 83.7073 73.3659 oryzias_sinensis ENSOSIP00000033980 86.8421 76.1134 ENSG00000188641 homo_sapiens ENSP00000359211 85.7561 79.5122 pelodiscus_sinensis ENSPSIP00000008689 92.6238 85.8799 ENSG00000188641 homo_sapiens ENSP00000359211 39.0244 36.6829 gopherus_evgoodei ENSGEVP00005018429 89.2857 83.9286 ENSG00000188641 homo_sapiens ENSP00000359211 14.0488 13.0732 chelonoidis_abingdonii ENSCABP00000020341 84.2105 78.3626 ENSG00000188641 homo_sapiens ENSP00000359211 42.2439 39.5122 chelonoidis_abingdonii ENSCABP00000020344 90.9664 85.084 ENSG00000188641 homo_sapiens ENSP00000359211 86.8293 76 seriola_dumerili ENSSDUP00000019064 87.1694 76.2977 ENSG00000188641 homo_sapiens ENSP00000359211 81.4634 70.6341 cottoperca_gobio ENSCGOP00000044309 85.2911 73.953 ENSG00000188641 homo_sapiens ENSP00000359211 86.2439 78.439 struthio_camelus_australis ENSSCUP00000019291 91.0402 82.8012 ENSG00000188641 homo_sapiens ENSP00000359211 92.5854 85.4634 anser_brachyrhynchus ENSABRP00000017080 92.6758 85.5469 ENSG00000188641 homo_sapiens ENSP00000359211 86.8293 75.9024 gasterosteus_aculeatus ENSGACP00000019655 86.999 76.0508 ENSG00000188641 homo_sapiens ENSP00000359211 87.7073 76.7805 cynoglossus_semilaevis ENSCSEP00000028161 88.0509 77.0813 ENSG00000188641 homo_sapiens ENSP00000359211 87.1219 76.5854 poecilia_formosa ENSPFOP00000005844 87.037 76.5107 ENSG00000188641 homo_sapiens ENSP00000359211 84.0976 72.9756 myripristis_murdjan ENSMMDP00005049917 85.7711 74.4279 ENSG00000188641 homo_sapiens ENSP00000359211 86.6341 75.9024 sander_lucioperca ENSSLUP00000059752 86.5497 75.8285 ENSG00000188641 homo_sapiens ENSP00000359211 92.2927 84.8781 strigops_habroptila ENSSHBP00005015772 91.5779 84.2207 ENSG00000188641 homo_sapiens ENSP00000359211 87.8049 76.1951 amphiprion_ocellaris ENSAOCP00000011473 87.7193 76.1209 ENSG00000188641 homo_sapiens ENSP00000359211 92.4878 85.7561 terrapene_carolina_triunguis ENSTMTP00000005392 92.4878 85.7561 ENSG00000188641 homo_sapiens ENSP00000359211 92.4878 85.6585 terrapene_carolina_triunguis ENSTMTP00000004920 92.4878 85.6585 ENSG00000188641 homo_sapiens ENSP00000359211 88.3902 75.6098 hucho_hucho ENSHHUP00000030778 87.6209 74.9516 ENSG00000188641 homo_sapiens ENSP00000359211 47.5122 37.2683 hucho_hucho ENSHHUP00000084428 70.6822 55.4427 ENSG00000188641 homo_sapiens ENSP00000359211 86.6341 75.6098 hucho_hucho ENSHHUP00000009273 86.7188 75.6836 ENSG00000188641 homo_sapiens ENSP00000359211 84.7805 73.3659 betta_splendens ENSBSLP00000053002 84.1239 72.7977 ENSG00000188641 homo_sapiens ENSP00000359211 88.2927 76.7805 pygocentrus_nattereri ENSPNAP00000015859 88.2066 76.7057 ENSG00000188641 homo_sapiens ENSP00000359211 85.6585 75.0244 anabas_testudineus ENSATEP00000049729 85.6585 75.0244 ENSG00000188641 homo_sapiens ENSP00000359211 83.2195 69.8537 ciona_savignyi ENSCSAVP00000006746 82.2565 69.0453 ENSG00000188641 homo_sapiens ENSP00000359211 15.2195 9.46341 saccharomyces_cerevisiae YKL216W 49.6815 30.8917 ENSG00000188641 homo_sapiens ENSP00000359211 78.8293 67.6098 seriola_lalandi_dorsalis ENSSLDP00000008903 82.1974 70.4985 ENSG00000188641 homo_sapiens ENSP00000359211 87.1219 75.6098 labrus_bergylta ENSLBEP00000027765 87.2923 75.7576 ENSG00000188641 homo_sapiens ENSP00000359211 86.8293 75.1219 pundamilia_nyererei ENSPNYP00000016785 87.1694 75.4163 ENSG00000188641 homo_sapiens ENSP00000359211 87.3171 75.3171 mastacembelus_armatus ENSMAMP00000017213 87.5734 75.5382 ENSG00000188641 homo_sapiens ENSP00000359211 84.5854 73.6585 stegastes_partitus ENSSPAP00000008533 87.3992 76.1089 ENSG00000188641 homo_sapiens ENSP00000359211 88.5854 76.0976 oncorhynchus_tshawytscha ENSOTSP00005075152 86.724 74.4986 ENSG00000188641 homo_sapiens ENSP00000359211 82.5366 71.7073 oncorhynchus_tshawytscha ENSOTSP00005050289 82.6979 71.8475 ENSG00000188641 homo_sapiens ENSP00000359211 87.6098 75.8049 acanthochromis_polyacanthus ENSAPOP00000007493 87.5244 75.731 ENSG00000188641 homo_sapiens ENSP00000359211 92.8781 85.6585 aquila_chrysaetos_chrysaetos ENSACCP00020014390 92.8781 85.6585 ENSG00000188641 homo_sapiens ENSP00000359211 84.4878 73.9512 nothobranchius_furzeri ENSNFUP00015049110 85.998 75.2731 ENSG00000188641 homo_sapiens ENSP00000359211 87.2195 76.4878 cyprinodon_variegatus ENSCVAP00000029579 87.4755 76.7123 ENSG00000188641 homo_sapiens ENSP00000359211 89.0732 77.561 denticeps_clupeoides ENSDCDP00000027876 88.9864 77.4854 ENSG00000188641 homo_sapiens ENSP00000359211 86.439 75.2195 larimichthys_crocea ENSLCRP00005033438 86.948 75.6624 ENSG00000188641 homo_sapiens ENSP00000359211 85.7561 74.5366 takifugu_rubripes ENSTRUP00000077471 86.0921 74.8286 ENSG00000188641 homo_sapiens ENSP00000359211 91.3171 83.3171 ficedula_albicollis ENSFALP00000025951 84.6293 77.2152 ENSG00000188641 homo_sapiens ENSP00000359211 82.439 71.6098 hippocampus_comes ENSHCOP00000012629 82.681 71.82 ENSG00000188641 homo_sapiens ENSP00000359211 87.7073 76.3902 cyprinus_carpio_carpio ENSCCRP00000137357 83.7058 72.905 ENSG00000188641 homo_sapiens ENSP00000359211 14.439 12.3902 cyprinus_carpio_carpio ENSCCRP00000113910 64.9123 55.7018 ENSG00000188641 homo_sapiens ENSP00000359211 86.3415 75.7073 cyprinus_carpio_carpio ENSCCRP00000100990 83.4119 73.1385 ENSG00000188641 homo_sapiens ENSP00000359211 80.4878 69.6585 cyprinus_carpio_carpio ENSCCRP00000107015 83.6714 72.4138 ENSG00000188641 homo_sapiens ENSP00000359211 88.0976 81.1707 coturnix_japonica ENSCJPP00005000256 89.4059 82.3762 ENSG00000188641 homo_sapiens ENSP00000359211 87.1219 76.5854 poecilia_latipinna ENSPLAP00000031309 87.037 76.5107 ENSG00000188641 homo_sapiens ENSP00000359211 28.3902 23.122 sinocyclocheilus_grahami ENSSGRP00000070481 78.2258 63.7097 ENSG00000188641 homo_sapiens ENSP00000359211 69.4634 58.9268 sinocyclocheilus_grahami ENSSGRP00000081734 78.1559 66.3008 ENSG00000188641 homo_sapiens ENSP00000359211 85.0732 75.2195 sinocyclocheilus_grahami ENSSGRP00000057933 81.7245 72.2587 ENSG00000188641 homo_sapiens ENSP00000359211 86.5366 75.5122 sinocyclocheilus_grahami ENSSGRP00000100270 85.8664 74.9274 ENSG00000188641 homo_sapiens ENSP00000359211 16.2927 14.439 sinocyclocheilus_grahami ENSSGRP00000108316 83.5 74 ENSG00000188641 homo_sapiens ENSP00000359211 86.7317 75.0244 maylandia_zebra ENSMZEP00005014216 87.0715 75.3183 ENSG00000188641 homo_sapiens ENSP00000359211 86.3415 75.7073 tetraodon_nigroviridis ENSTNIP00000008249 86.1733 75.5599 ENSG00000188641 homo_sapiens ENSP00000359211 87.4146 75.9024 paramormyrops_kingsleyae ENSPKIP00000025427 87.5 75.9766 ENSG00000188641 homo_sapiens ENSP00000359211 87.4146 76 scleropages_formosus ENSSFOP00015049179 85.6597 74.4742 ENSG00000188641 homo_sapiens ENSP00000359211 89.4634 80.2927 leptobrachium_leishanense ENSLLEP00000042245 89.4634 80.2927 ENSG00000188641 homo_sapiens ENSP00000359211 86.8293 74.6341 scophthalmus_maximus ENSSMAP00000002016 86.9141 74.707 ENSG00000188641 homo_sapiens ENSP00000359211 86.8293 75.9024 oryzias_melastigma ENSOMEP00000031919 87.1694 76.1998
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0002058 enables uracil binding 1 IBA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005737 located_in cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0005829 is_active_in cytosol 3 IBA,IDA,TAS Homo_sapiens(9606) Component GO:0006145 involved_in purine nucleobase catabolic process 1 IMP Homo_sapiens(9606) Process GO:0006208 involved_in pyrimidine nucleobase catabolic process 2 IMP,ISS Homo_sapiens(9606) Process GO:0006210 involved_in thymine catabolic process 2 IBA,IDA Homo_sapiens(9606) Process GO:0006212 involved_in uracil catabolic process 2 IBA,IDA Homo_sapiens(9606) Process GO:0006214 involved_in thymidine catabolic process 1 IDA Homo_sapiens(9606) Process GO:0006248 involved_in CMP catabolic process 1 IEA Homo_sapiens(9606) Process GO:0006249 involved_in dCMP catabolic process 1 IEA Homo_sapiens(9606) Process GO:0017113 enables dihydropyrimidine dehydrogenase (NADP+) activity 4 IBA,IDA,IMP,ISS Homo_sapiens(9606) Function GO:0019483 involved_in beta-alanine biosynthetic process 1 IEA Homo_sapiens(9606) Process GO:0042803 enables protein homodimerization activity 2 IDA,ISS Homo_sapiens(9606) Function GO:0046050 involved_in UMP catabolic process 1 IEA Homo_sapiens(9606) Process GO:0046079 involved_in dUMP catabolic process 1 IEA Homo_sapiens(9606) Process GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:0050660 enables flavin adenine dinucleotide binding 1 ISS Homo_sapiens(9606) Function GO:0050661 enables NADP binding 2 IBA,ISS Homo_sapiens(9606) Function GO:0051539 enables 4 iron, 4 sulfur cluster binding 1 IEA Homo_sapiens(9606) Function
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