RBP Type	Non-canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000187837	Gene ID	3006	Accession	4716
Symbol	H1-2	Alias	H1C;H1.2;H1F2;H1s-1;HIST1H1C	Full Name	H1.2 linker histone, cluster member
Status	Confidence	Length	731 bases	Strand	Minus strand
Position	6 : 26055740 - 26056470	RNA binding domain	N.A.
Summary	Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000187837	homo_sapiens	ENSP00000344504	57.732	45.8763	homo_sapiens	ENSP00000339566	52.5822	41.784
ENSG00000187837	homo_sapiens	ENSP00000329662	46.4789	32.8638	homo_sapiens	ENSP00000339566	46.4789	32.8638
ENSG00000187837	homo_sapiens	ENSP00000341214	63.7681	52.1739	homo_sapiens	ENSP00000339566	61.9718	50.7042
ENSG00000187837	homo_sapiens	ENSP00000319799	30.9249	22.2543	homo_sapiens	ENSP00000339566	50.2347	36.1502
ENSG00000187837	homo_sapiens	ENSP00000334805	36.0784	20	homo_sapiens	ENSP00000339566	43.1925	23.9437
ENSG00000187837	homo_sapiens	ENSP00000244573	73.9535	67.4419	homo_sapiens	ENSP00000339566	74.6479	68.0751
ENSG00000187837	homo_sapiens	ENSP00000330074	78.7611	76.5487	homo_sapiens	ENSP00000339566	83.5681	81.2207
ENSG00000187837	homo_sapiens	ENSP00000307705	84.9315	84.9315	homo_sapiens	ENSP00000339566	87.3239	87.3239
ENSG00000187837	homo_sapiens	ENSP00000244534	81.448	80.0905	homo_sapiens	ENSP00000339566	84.507	83.0986

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000187837	homo_sapiens	ENSP00000339566	98.5916	98.5916	nomascus_leucogenys	ENSNLEP00000022249	98.5916	98.5916
ENSG00000187837	homo_sapiens	ENSP00000339566	99.5305	99.5305	pan_paniscus	ENSPPAP00000003375	99.5305	99.5305
ENSG00000187837	homo_sapiens	ENSP00000339566	99.5305	99.5305	pongo_abelii	ENSPPYP00000018233	99.5305	99.5305
ENSG00000187837	homo_sapiens	ENSP00000339566	99.5305	99.5305	pan_troglodytes	ENSPTRP00000030392	99.5305	99.5305
ENSG00000187837	homo_sapiens	ENSP00000339566	100	100	gorilla_gorilla	ENSGGOP00000007505	100	100
ENSG00000187837	homo_sapiens	ENSP00000339566	84.0376	80.2817	ornithorhynchus_anatinus	ENSOANP00000034053	78.5088	75
ENSG00000187837	homo_sapiens	ENSP00000339566	51.6432	48.3568	notamacropus_eugenii	ENSMEUP00000000814	88.7097	83.0645
ENSG00000187837	homo_sapiens	ENSP00000339566	89.6714	89.2019	dasypus_novemcinctus	ENSDNOP00000026389	91.3876	90.9091
ENSG00000187837	homo_sapiens	ENSP00000339566	91.0798	89.6714	erinaceus_europaeus	ENSEEUP00000002492	91.5094	90.0943
ENSG00000187837	homo_sapiens	ENSP00000339566	94.8357	93.8967	callithrix_jacchus	ENSCJAP00000057041	94.8357	93.8967
ENSG00000187837	homo_sapiens	ENSP00000339566	95.7747	94.3662	macaca_fascicularis	ENSMFAP00000063868	95.7747	94.3662
ENSG00000187837	homo_sapiens	ENSP00000339566	88.7324	87.7934	macaca_mulatta	ENSMMUP00000065077	96.9231	95.8974
ENSG00000187837	homo_sapiens	ENSP00000339566	96.2441	94.3662	papio_anubis	ENSPANP00000049195	96.2441	94.3662
ENSG00000187837	homo_sapiens	ENSP00000339566	76.9953	71.3615	vulpes_vulpes	ENSVVUP00000035148	78.0952	72.381
ENSG00000187837	homo_sapiens	ENSP00000339566	74.6479	70.892	vulpes_vulpes	ENSVVUP00000001140	74.6479	70.892
ENSG00000187837	homo_sapiens	ENSP00000339566	87.7934	87.3239	vulpes_vulpes	ENSVVUP00000035069	86.9767	86.5116
ENSG00000187837	homo_sapiens	ENSP00000339566	89.6714	88.2629	mus_spretus	MGP_SPRETEiJ_P0035458	90.0943	88.6792
ENSG00000187837	homo_sapiens	ENSP00000339566	84.9765	84.9765	equus_asinus	ENSEASP00005042030	92.3469	92.3469
ENSG00000187837	homo_sapiens	ENSP00000339566	91.0798	90.1408	capra_hircus	ENSCHIP00000024891	85.4626	84.5815
ENSG00000187837	homo_sapiens	ENSP00000339566	78.4038	77.9343	loxodonta_africana	ENSLAFP00000022030	91.2568	90.7104
ENSG00000187837	homo_sapiens	ENSP00000339566	90.6103	90.6103	panthera_leo	ENSPLOP00000017775	90.6103	90.6103
ENSG00000187837	homo_sapiens	ENSP00000339566	86.8545	86.385	ailuropoda_melanoleuca	ENSAMEP00000016813	84.0909	83.6364
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	91.0798	bos_indicus_hybrid	ENSBIXP00005031323	86.3436	85.4626
ENSG00000187837	homo_sapiens	ENSP00000339566	85.446	80.7512	oryctolagus_cuniculus	ENSOCUP00000019095	49.0566	46.3612
ENSG00000187837	homo_sapiens	ENSP00000339566	85.446	85.446	equus_caballus	ENSECAP00000061340	92.8571	92.8571
ENSG00000187837	homo_sapiens	ENSP00000339566	92.9577	92.0188	canis_lupus_familiaris	ENSCAFP00845035339	92.9577	92.0188
ENSG00000187837	homo_sapiens	ENSP00000339566	90.6103	90.6103	panthera_pardus	ENSPPRP00000025183	90.6103	90.6103
ENSG00000187837	homo_sapiens	ENSP00000339566	91.5493	90.1408	marmota_marmota_marmota	ENSMMMP00000001987	91.9811	90.566
ENSG00000187837	homo_sapiens	ENSP00000339566	90.6103	87.3239	balaenoptera_musculus	ENSBMSP00010014372	90.6103	87.3239
ENSG00000187837	homo_sapiens	ENSP00000339566	92.4883	91.5493	cavia_porcellus	ENSCPOP00000020422	92.4883	91.5493
ENSG00000187837	homo_sapiens	ENSP00000339566	89.2019	87.3239	felis_catus	ENSFCAP00000003509	57.4018	56.1934
ENSG00000187837	homo_sapiens	ENSP00000339566	91.5493	90.6103	bison_bison_bison	ENSBBBP00000028603	77.381	76.5873
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	89.6714	monodon_monoceros	ENSMMNP00015016300	92.0188	89.6714
ENSG00000187837	homo_sapiens	ENSP00000339566	89.6714	87.7934	jaculus_jaculus	ENSJJAP00000009017	90.5213	88.6256
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	91.0798	ovis_aries_rambouillet	ENSOARP00020008981	92.0188	91.0798
ENSG00000187837	homo_sapiens	ENSP00000339566	90.6103	90.1408	ursus_maritimus	ENSUMAP00000028751	90.6103	90.1408
ENSG00000187837	homo_sapiens	ENSP00000339566	90.6103	90.1408	ochotona_princeps	ENSOPRP00000012878	90.6103	90.1408
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	89.6714	delphinapterus_leucas	ENSDLEP00000026608	92.0188	89.6714
ENSG00000187837	homo_sapiens	ENSP00000339566	92.4883	90.6103	physeter_catodon	ENSPCTP00005014394	92.4883	90.6103
ENSG00000187837	homo_sapiens	ENSP00000339566	89.2019	87.7934	mus_caroli	MGP_CAROLIEiJ_P0033878	89.6226	88.2076
ENSG00000187837	homo_sapiens	ENSP00000339566	89.6714	88.2629	mus_musculus	ENSMUSP00000045816	90.0943	88.6792
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	88.7324	aotus_nancymaae	ENSANAP00000014052	89.9083	86.6973
ENSG00000187837	homo_sapiens	ENSP00000339566	89.2019	86.385	aotus_nancymaae	ENSANAP00000017805	93.1373	90.1961
ENSG00000187837	homo_sapiens	ENSP00000339566	95.7747	94.8357	aotus_nancymaae	ENSANAP00000004145	95.7747	94.8357
ENSG00000187837	homo_sapiens	ENSP00000339566	89.2019	88.7324	vicugna_pacos	ENSVPAP00000007650	92.233	91.7476
ENSG00000187837	homo_sapiens	ENSP00000339566	95.7747	94.3662	chlorocebus_sabaeus	ENSCSAP00000018606	95.7747	94.3662
ENSG00000187837	homo_sapiens	ENSP00000339566	91.0798	89.2019	mesocricetus_auratus	ENSMAUP00000020118	91.9431	90.0474
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	89.6714	phocoena_sinus	ENSPSNP00000007701	92.0188	89.6714
ENSG00000187837	homo_sapiens	ENSP00000339566	92.9577	92.4883	camelus_dromedarius	ENSCDRP00005005063	92.9577	92.4883
ENSG00000187837	homo_sapiens	ENSP00000339566	89.2019	88.2629	rattus_norvegicus	ENSRNOP00000077080	89.6226	88.6792
ENSG00000187837	homo_sapiens	ENSP00000339566	91.0798	90.1408	prolemur_simus	ENSPSMP00000006810	91.0798	90.1408
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	90.1408	microtus_ochrogaster	ENSMOCP00000003292	92.4528	90.566
ENSG00000187837	homo_sapiens	ENSP00000339566	91.5493	89.6714	sorex_araneus	ENSSARP00000004372	91.5493	89.6714
ENSG00000187837	homo_sapiens	ENSP00000339566	91.5493	90.6103	peromyscus_maniculatus_bairdii	ENSPEMP00000005725	91.9811	91.0377
ENSG00000187837	homo_sapiens	ENSP00000339566	92.4883	91.5493	bos_mutus	ENSBMUP00000000991	92.4883	91.5493
ENSG00000187837	homo_sapiens	ENSP00000339566	91.5493	90.1408	cricetulus_griseus_chok1gshd	ENSCGRP00001007585	91.9811	90.566
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	92.0188	pteropus_vampyrus	ENSPVAP00000016597	92.0188	92.0188
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	89.2019	rhinolophus_ferrumequinum	ENSRFEP00010025242	92.0188	89.2019
ENSG00000187837	homo_sapiens	ENSP00000339566	90.1408	89.6714	neovison_vison	ENSNVIP00000007890	66.6667	66.3194
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	91.0798	bos_taurus	ENSBTAP00000015499	86.3436	85.4626
ENSG00000187837	homo_sapiens	ENSP00000339566	90.1408	88.7324	heterocephalus_glaber_female	ENSHGLP00000050393	90.566	89.1509
ENSG00000187837	homo_sapiens	ENSP00000339566	87.3239	85.446	canis_lupus_dingo	ENSCAFP00020011164	86.5116	84.6512
ENSG00000187837	homo_sapiens	ENSP00000339566	87.3239	86.385	canis_lupus_dingo	ENSCAFP00020002847	85.3211	84.4037
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	90.6103	sciurus_vulgaris	ENSSVLP00005018446	92.4528	91.0377
ENSG00000187837	homo_sapiens	ENSP00000339566	90.1408	88.2629	procavia_capensis	ENSPCAP00000003345	90.566	88.6792
ENSG00000187837	homo_sapiens	ENSP00000339566	90.1408	89.2019	nannospalax_galili	ENSNGAP00000003587	90.9953	90.0474
ENSG00000187837	homo_sapiens	ENSP00000339566	84.507	84.0376	bos_grunniens	ENSBGRP00000024728	93.2643	92.7461
ENSG00000187837	homo_sapiens	ENSP00000339566	90.1408	89.2019	chinchilla_lanigera	ENSCLAP00000025436	90.1408	89.2019
ENSG00000187837	homo_sapiens	ENSP00000339566	92.4883	91.5493	cervus_hanglu_yarkandensis	ENSCHYP00000012645	92.4883	91.5493
ENSG00000187837	homo_sapiens	ENSP00000339566	92.4883	91.5493	catagonus_wagneri	ENSCWAP00000011049	92.4883	91.5493
ENSG00000187837	homo_sapiens	ENSP00000339566	91.5493	90.1408	ictidomys_tridecemlineatus	ENSSTOP00000016043	91.9811	90.566
ENSG00000187837	homo_sapiens	ENSP00000339566	92.0188	91.5493	otolemur_garnettii	ENSOGAP00000020429	92.0188	91.5493
ENSG00000187837	homo_sapiens	ENSP00000339566	91.5493	90.1408	urocitellus_parryii	ENSUPAP00010007333	91.9811	90.566
ENSG00000187837	homo_sapiens	ENSP00000339566	92.9577	91.5493	moschus_moschiferus	ENSMMSP00000014467	92.9577	91.5493
ENSG00000187837	homo_sapiens	ENSP00000339566	90.6103	88.7324	mus_pahari	MGP_PahariEiJ_P0040481	91.0377	89.1509
ENSG00000187837	homo_sapiens	ENSP00000339566	35.6808	28.169	caenorhabditis_elegans	F59A7.4.1	40	31.5789
ENSG00000187837	homo_sapiens	ENSP00000339566	38.4977	30.5164	caenorhabditis_elegans	Y73B6BL.9a.1	42.9319	34.0314
ENSG00000187837	homo_sapiens	ENSP00000339566	38.4977	31.4554	caenorhabditis_elegans	F22F1.1.1	39.4231	32.2115
ENSG00000187837	homo_sapiens	ENSP00000339566	38.9671	29.108	caenorhabditis_elegans	C18G1.5.1	32.8063	24.5059
ENSG00000187837	homo_sapiens	ENSP00000339566	38.0282	30.0469	caenorhabditis_elegans	B0414.3.1	36	28.4444
ENSG00000187837	homo_sapiens	ENSP00000339566	51.6432	44.1315	sphenodon_punctatus	ENSSPUP00000024232	63.9535	54.6512
ENSG00000187837	homo_sapiens	ENSP00000339566	45.0704	40.8451	sphenodon_punctatus	ENSSPUP00000024440	64.4295	58.3893
ENSG00000187837	homo_sapiens	ENSP00000339566	61.0329	53.5211	serinus_canaria	ENSSCAP00000014465	54.3933	47.6987

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000122	involved_in negative regulation of transcription by RNA polymerase II	1	IEA	Homo_sapiens(9606)	Process
GO:0000786	part_of nucleosome	1	IEA	Homo_sapiens(9606)	Component
GO:0000791	part_of euchromatin	1	IDA	Homo_sapiens(9606)	Component
GO:0003690	enables double-stranded DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0006334	involved_in nucleosome assembly	1	IEA	Homo_sapiens(9606)	Process
GO:0030261	involved_in chromosome condensation	1	IBA	Homo_sapiens(9606)	Process
GO:0030527	enables structural constituent of chromatin	1	IEA	Homo_sapiens(9606)	Function
GO:0031490	enables chromatin DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0031492	enables nucleosomal DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0045910	involved_in negative regulation of DNA recombination	1	IBA	Homo_sapiens(9606)	Process
GO:0080182	involved_in histone H3-K4 trimethylation	1	IEA	Homo_sapiens(9606)	Process
GO:0098532	involved_in histone H3-K27 trimethylation	1	IEA	Homo_sapiens(9606)	Process