RBP Type
Canonical_RBPs
Diseases
SARS-COV-OC43 Flaviviruses SARS-COV-2 SINV Dengue Zika
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
TF
Localizations
Stress granucle
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000185129 Gene ID
5813 Accession
9701
Symbol
PURA
Alias
PUR1;MRD31;NEDRIHF;PURALPHA;PUR-ALPHA
Full Name
purine rich element binding protein A
Status
Confidence
Length
17843 bases
Strand
Plus strand
Position
5 : 140107777 - 140125619
RNA binding domain
PurA
Summary
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000332706
PurA
PF04845 6.3e-108
1
ENSP00000499133
PurA
PF04845 6.3e-108
1
ENSP00000498560
PurA
PF04845 1.2e-22
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
28977530 Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing.
Ayan Banerjee
2017-10-13
Nucleic acids research
33777106 The Molecular Function of PURA and Its Implications in Neurological Diseases.
Lena Molitor
2021-01-01
Frontiers in genetics
32476604 The large family of PC4-like domains - similar folds and functions throughout all kingdoms of life.
Robert Janowski
2020-09-01
RNA biology
23473314 The unstable repeats--three evolving faces of neurological disease.
L David Nelson
2013-03-06
Neuron
36651277 Depletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies.
Lena Molitor
2023-02-22
Nucleic acids research
21151833 Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5.
G Peter Hawkins
2010-11-01
Transcription
29221753 PURA, the gene encoding Pur-alpha, member of an ancient nucleic acid-binding protein family with mammalian neurological functions.
C Dianne Daniel
2018-02-15
Gene
32035967 A synthetic Pur-based peptide binds and alters G-quadruplex secondary structure present in the expanded RNA repeat of C9orf72 ALS/FTD.
J Margaret Wortman
2020-06-01
Biochimica et biophysica acta. Molecular cell research
29307761 A frame-shift deletion in the PURA gene associates with a new clinical finding: Hypoglycorrhachia. Is GLUT1 a new PURA target?
Lía Mayorga
2018-03-01
Molecular genetics and metabolism
37149929 Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis.
Wen Wen Xu
2023-06-01
EBioMedicine
33750045 Novel frameshift mutation in PURA gene causes severe encephalopathy of unclear cause.
Lucía Spangenberg
2021-05-01
Molecular genetics & genomic medicine
35884678 Structural Protein Effects Underpinning Cognitive Developmental Delay of the PURA p.Phe233del Mutation Modelled by Artificial Intelligence and the Hybrid Quantum Mechanics-Molecular Mechanics Framework.
Javier Juan López-Rivera
2022-06-30
Brain sciences
30698743 Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptome.
Lichao Liu
2019-03-18
Nucleic acids research
23749060 Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition.
L John Goodier
2013-08-01
Nucleic acids research
36768582 Neuromuscular and Neuromuscular Junction Manifestations of the PURA-NDD: A Systematic Review of the Reported Symptoms and Potential Treatment Options.
Magdalena Mroczek
2023-01-23
International journal of molecular sciences
Name
Transcript ID
bp
Protein
Translation ID
PURA-203
ENST00000505703
784
106aa
ENSP00000498560
PURA-204
ENST00000651386
1919
322aa
ENSP00000499133
PURA-205
ENST00000676000
415
No protein
-
PURA-202
ENST00000502351
502
26aa
ENSP00000498760
PURA-201
ENST00000331327
11511
322aa
ENSP00000332706
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000185129 homo_sapiens ENSP00000379051 74.6795 66.9872 homo_sapiens ENSP00000332706 72.3602 64.9068 ENSG00000185129 homo_sapiens ENSP00000466881 58.7896 49.8559 homo_sapiens ENSP00000332706 63.354 53.7267
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000185129 homo_sapiens ENSP00000332706 81.0559 80.1242 pan_paniscus ENSPPAP00000039432 90.625 89.5833 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 pongo_abelii ENSPPYP00000017720 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 90.3727 90.0621 gorilla_gorilla ENSGGOP00000002168 95.4098 95.082 ENSG00000185129 homo_sapiens ENSP00000332706 96.2733 95.9627 ornithorhynchus_anatinus ENSOANP00000039373 93.3735 93.0723 ENSG00000185129 homo_sapiens ENSP00000332706 96.8944 96.5839 sarcophilus_harrisii ENSSHAP00000038683 99.3631 99.0446 ENSG00000185129 homo_sapiens ENSP00000332706 63.354 63.0435 notamacropus_eugenii ENSMEUP00000004031 100 99.5098 ENSG00000185129 homo_sapiens ENSP00000332706 99.3789 99.3789 dasypus_novemcinctus ENSDNOP00000019152 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 99.6894 99.6894 callithrix_jacchus ENSCJAP00000062289 72.4605 72.4605 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 macaca_mulatta ENSMMUP00000042328 80.7018 80.7018 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 papio_anubis ENSPANP00000055570 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 83.5404 82.6087 mandrillus_leucophaeus ENSMLEP00000026061 89.0728 88.0795 ENSG00000185129 homo_sapiens ENSP00000332706 99.3789 99.3789 tursiops_truncatus ENSTTRP00000010824 98.4615 98.4615 ENSG00000185129 homo_sapiens ENSP00000332706 89.7516 88.5093 vulpes_vulpes ENSVVUP00000013774 61.3588 60.5096 ENSG00000185129 homo_sapiens ENSP00000332706 98.7578 98.7578 mus_spretus MGP_SPRETEiJ_P0048303 99.0654 99.0654 ENSG00000185129 homo_sapiens ENSP00000332706 93.4783 92.5466 equus_asinus ENSEASP00005030733 61.5542 60.9407 ENSG00000185129 homo_sapiens ENSP00000332706 99.0683 99.0683 capra_hircus ENSCHIP00000005212 99.0683 99.0683 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 panthera_leo ENSPLOP00000003259 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 94.0994 93.1677 ailuropoda_melanoleuca ENSAMEP00000011772 92.3781 91.4634 ENSG00000185129 homo_sapiens ENSP00000332706 99.0683 99.0683 bos_indicus_hybrid ENSBIXP00005008993 99.0683 99.0683 ENSG00000185129 homo_sapiens ENSP00000332706 99.6894 99.6894 oryctolagus_cuniculus ENSOCUP00000009570 69.7826 69.7826 ENSG00000185129 homo_sapiens ENSP00000332706 99.3789 99.3789 equus_caballus ENSECAP00000056594 65.5738 65.5738 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 canis_lupus_familiaris ENSCAFP00845001547 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 panthera_pardus ENSPPRP00000026846 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 94.7205 93.4783 balaenoptera_musculus ENSBMSP00010005352 94.4272 93.1889 ENSG00000185129 homo_sapiens ENSP00000332706 96.8944 96.5839 monodelphis_domestica ENSMODP00000014683 83.4225 83.1551 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 81.677 bison_bison_bison ENSBBBP00000003391 80.6748 80.6748 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 monodon_monoceros ENSMMNP00015000777 99.6904 99.6904 ENSG00000185129 homo_sapiens ENSP00000332706 99.6894 99.6894 sus_scrofa ENSSSCP00000070354 66.5975 66.5975 ENSG00000185129 homo_sapiens ENSP00000332706 90.6832 90.6832 octodon_degus ENSODEP00000004556 90.9657 90.9657 ENSG00000185129 homo_sapiens ENSP00000332706 87.5776 86.646 jaculus_jaculus ENSJJAP00000011921 89.8089 88.8535 ENSG00000185129 homo_sapiens ENSP00000332706 99.0683 99.0683 ovis_aries_rambouillet ENSOARP00020026488 99.0683 99.0683 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 physeter_catodon ENSPCTP00005026141 99.6904 99.6904 ENSG00000185129 homo_sapiens ENSP00000332706 98.7578 98.7578 mus_caroli MGP_CAROLIEiJ_P0046375 99.0654 99.0654 ENSG00000185129 homo_sapiens ENSP00000332706 98.7578 98.7578 mus_musculus ENSMUSP00000059404 99.0654 99.0654 ENSG00000185129 homo_sapiens ENSP00000332706 90.0621 89.7516 dipodomys_ordii ENSDORP00000007807 95.082 94.7541 ENSG00000185129 homo_sapiens ENSP00000332706 90.3727 88.1988 mustela_putorius_furo ENSMPUP00000008923 92.0886 89.8734 ENSG00000185129 homo_sapiens ENSP00000332706 89.7516 89.7516 aotus_nancymaae ENSANAP00000035939 95.0658 95.0658 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 chlorocebus_sabaeus ENSCSAP00000017509 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 95.9627 95.9627 mesocricetus_auratus ENSMAUP00000010004 96.2617 96.2617 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 phocoena_sinus ENSPSNP00000016308 99.6904 99.6904 ENSG00000185129 homo_sapiens ENSP00000332706 88.8199 88.8199 camelus_dromedarius ENSCDRP00005000131 93.1596 93.1596 ENSG00000185129 homo_sapiens ENSP00000332706 70.1863 68.9441 carlito_syrichta ENSTSYP00000012260 86.59 85.0575 ENSG00000185129 homo_sapiens ENSP00000332706 98.7578 98.7578 rattus_norvegicus ENSRNOP00000081821 99.0654 99.0654 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 77.9503 prolemur_simus ENSPSMP00000027564 77.9503 77.9503 ENSG00000185129 homo_sapiens ENSP00000332706 98.4472 98.4472 microtus_ochrogaster ENSMOCP00000008793 99.0625 99.0625 ENSG00000185129 homo_sapiens ENSP00000332706 82.9193 82.9193 sorex_araneus ENSSARP00000008246 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 98.7578 98.7578 peromyscus_maniculatus_bairdii ENSPEMP00000036893 99.0654 99.0654 ENSG00000185129 homo_sapiens ENSP00000332706 98.7578 98.7578 mus_spicilegus ENSMSIP00000035942 99.0654 99.0654 ENSG00000185129 homo_sapiens ENSP00000332706 98.7578 98.7578 cricetulus_griseus_chok1gshd ENSCGRP00001004026 99.0654 99.0654 ENSG00000185129 homo_sapiens ENSP00000332706 99.3789 99.3789 pteropus_vampyrus ENSPVAP00000009134 99.0712 99.0712 ENSG00000185129 homo_sapiens ENSP00000332706 93.7888 92.236 myotis_lucifugus ENSMLUP00000021591 92.638 91.1043 ENSG00000185129 homo_sapiens ENSP00000332706 96.8944 96.5839 vombatus_ursinus ENSVURP00010012411 99.3631 99.0446 ENSG00000185129 homo_sapiens ENSP00000332706 99.6894 99.6894 rhinolophus_ferrumequinum ENSRFEP00010015590 67.7215 67.7215 ENSG00000185129 homo_sapiens ENSP00000332706 99.0683 99.0683 bos_taurus ENSBTAP00000040759 99.0683 99.0683 ENSG00000185129 homo_sapiens ENSP00000332706 99.3789 99.3789 heterocephalus_glaber_female ENSHGLP00000028434 99.6885 99.6885 ENSG00000185129 homo_sapiens ENSP00000332706 85.0932 85.0932 rhinopithecus_bieti ENSRBIP00000006753 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 canis_lupus_dingo ENSCAFP00020003615 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 99.3789 99.3789 sciurus_vulgaris ENSSVLP00005029093 99.0712 99.0712 ENSG00000185129 homo_sapiens ENSP00000332706 86.646 86.3354 phascolarctos_cinereus ENSPCIP00000021159 99.6429 99.2857 ENSG00000185129 homo_sapiens ENSP00000332706 97.8261 97.8261 procavia_capensis ENSPCAP00000012260 97.8261 97.8261 ENSG00000185129 homo_sapiens ENSP00000332706 90.9938 90.9938 nannospalax_galili ENSNGAP00000012045 99.6599 99.6599 ENSG00000185129 homo_sapiens ENSP00000332706 99.0683 99.0683 bos_grunniens ENSBGRP00000022648 99.0683 99.0683 ENSG00000185129 homo_sapiens ENSP00000332706 77.0186 76.087 chinchilla_lanigera ENSCLAP00000025515 95.3846 94.2308 ENSG00000185129 homo_sapiens ENSP00000332706 99.0683 99.0683 cervus_hanglu_yarkandensis ENSCHYP00000027228 99.0683 99.0683 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 catagonus_wagneri ENSCWAP00000010794 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 82.6087 82.6087 ictidomys_tridecemlineatus ENSSTOP00000000078 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 99.3789 99.3789 otolemur_garnettii ENSOGAP00000003006 99.0712 99.0712 ENSG00000185129 homo_sapiens ENSP00000332706 100 100 urocitellus_parryii ENSUPAP00010028006 100 100 ENSG00000185129 homo_sapiens ENSP00000332706 98.7578 98.7578 mus_pahari MGP_PahariEiJ_P0038977 99.0654 99.0654 ENSG00000185129 homo_sapiens ENSP00000332706 24.8447 15.528 caenorhabditis_elegans F20D1.4.1 41.6667 26.0417 ENSG00000185129 homo_sapiens ENSP00000332706 37.2671 26.087 caenorhabditis_elegans F45E4.2.1 53.0973 37.1681 ENSG00000185129 homo_sapiens ENSP00000332706 53.4161 39.7516 drosophila_melanogaster FBpp0089038 62.5455 46.5455 ENSG00000185129 homo_sapiens ENSP00000332706 58.6957 42.8571 ciona_intestinalis ENSCINP00000013060 61.7647 45.098 ENSG00000185129 homo_sapiens ENSP00000332706 76.3975 72.0497 petromyzon_marinus ENSPMAP00000011410 80.1303 75.57 ENSG00000185129 homo_sapiens ENSP00000332706 76.087 71.4286 eptatretus_burgeri ENSEBUP00000005718 83.3333 78.2313 ENSG00000185129 homo_sapiens ENSP00000332706 49.3789 41.9255 callorhinchus_milii ENSCMIP00000022973 73.2719 62.212 ENSG00000185129 homo_sapiens ENSP00000332706 85.7143 83.5404 latimeria_chalumnae ENSLACP00000019216 89.9023 87.6221 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.8137 lepisosteus_oculatus ENSLOCP00000022418 90.1024 87.7133 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.913 clupea_harengus ENSCHAP00000018354 90.942 86.2319 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.8137 clupea_harengus ENSCHAP00000060172 92.3077 89.8601 ENSG00000185129 homo_sapiens ENSP00000332706 78.2609 73.2919 danio_rerio ENSDARP00000130277 90.3226 84.5878 ENSG00000185129 homo_sapiens ENSP00000332706 82.6087 80.4348 danio_rerio ENSDARP00000101909 92.6829 90.2439 ENSG00000185129 homo_sapiens ENSP00000332706 77.0186 72.6708 carassius_auratus ENSCARP00000024369 89.5307 84.4765 ENSG00000185129 homo_sapiens ENSP00000332706 82.9193 80.4348 carassius_auratus ENSCARP00000124895 92.7083 89.9306 ENSG00000185129 homo_sapiens ENSP00000332706 82.6087 80.4348 carassius_auratus ENSCARP00000041723 92.6829 90.2439 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.9814 carassius_auratus ENSCARP00000060519 89.8917 84.8375 ENSG00000185129 homo_sapiens ENSP00000332706 78.882 73.913 astyanax_mexicanus ENSAMXP00000025655 84.106 78.8079 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 astyanax_mexicanus ENSAMXP00000026070 91.958 89.1608 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.913 ictalurus_punctatus ENSIPUP00000003073 88.6525 84.3972 ENSG00000185129 homo_sapiens ENSP00000332706 79.5031 77.3292 ictalurus_punctatus ENSIPUP00000034864 88.5813 86.1592 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 esox_lucius ENSELUP00000065522 83.758 81.2102 ENSG00000185129 homo_sapiens ENSP00000332706 78.2609 73.913 esox_lucius ENSELUP00000008152 90 85 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.6025 electrophorus_electricus ENSEEEP00000029532 89.0071 84.0426 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 78.5714 electrophorus_electricus ENSEEEP00000045245 92.2807 88.7719 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.2919 oncorhynchus_kisutch ENSOKIP00005083627 89.6429 84.2857 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.913 oncorhynchus_kisutch ENSOKIP00005029223 89.6429 85 ENSG00000185129 homo_sapiens ENSP00000332706 82.2981 79.8137 oncorhynchus_kisutch ENSOKIP00005098972 71.8157 69.6477 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.1925 oncorhynchus_kisutch ENSOKIP00005112143 92.6316 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 oncorhynchus_mykiss ENSOMYP00000123663 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.2919 oncorhynchus_mykiss ENSOMYP00000131861 89.6429 84.2857 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.913 oncorhynchus_mykiss ENSOMYP00000020914 89.6429 85 ENSG00000185129 homo_sapiens ENSP00000332706 82.2981 79.8137 oncorhynchus_mykiss ENSOMYP00000053152 64.7922 62.8362 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.2919 salmo_salar ENSSSAP00000147618 89.6429 84.2857 ENSG00000185129 homo_sapiens ENSP00000332706 73.2919 69.5652 salmo_salar ENSSSAP00000137150 92.1875 87.5 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 salmo_salar ENSSSAP00000128385 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 salmo_salar ENSSSAP00000177869 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.6025 salmo_trutta ENSSTUP00000003516 89.6429 84.6429 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.2919 salmo_trutta ENSSTUP00000082279 89.6429 84.2857 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 salmo_trutta ENSSTUP00000110157 67.3469 65.3061 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 salmo_trutta ENSSTUP00000017739 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 78.2609 74.2236 gadus_morhua ENSGMOP00000019579 89.6797 85.0534 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 gadus_morhua ENSGMOP00000025759 92.6056 89.7887 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.9814 fundulus_heteroclitus ENSFHEP00000030779 88.6121 83.6299 ENSG00000185129 homo_sapiens ENSP00000332706 80.1242 77.6398 fundulus_heteroclitus ENSFHEP00000014473 90.8451 88.0282 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 poecilia_reticulata ENSPREP00000028356 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 75.7764 71.7391 poecilia_reticulata ENSPREP00000006064 87.4552 82.7957 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.1925 xiphophorus_maculatus ENSXMAP00000019936 92.6316 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.6708 xiphophorus_maculatus ENSXMAP00000019480 88.6121 83.274 ENSG00000185129 homo_sapiens ENSP00000332706 81.3665 78.882 oryzias_latipes ENSORLP00000007668 91.9298 89.1228 ENSG00000185129 homo_sapiens ENSP00000332706 76.7081 72.0497 oryzias_latipes ENSORLP00000032894 87.9004 82.5623 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.8137 cyclopterus_lumpus ENSCLMP00005033185 92.6316 90.1754 ENSG00000185129 homo_sapiens ENSP00000332706 78.2609 73.913 cyclopterus_lumpus ENSCLMP00005039837 89.6797 84.6975 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 oreochromis_niloticus ENSONIP00000025960 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 oreochromis_niloticus ENSONIP00000026664 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 haplochromis_burtoni ENSHBUP00000003335 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 haplochromis_burtoni ENSHBUP00000021765 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 79.1925 77.3292 astatotilapia_calliptera ENSACLP00000028637 91.0714 88.9286 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 astatotilapia_calliptera ENSACLP00000033276 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 75.4658 72.3602 sparus_aurata ENSSAUP00010059807 89.011 85.348 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 sparus_aurata ENSSAUP00010019681 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 lates_calcarifer ENSLCAP00010018639 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 lates_calcarifer ENSLCAP00010053856 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 76.7081 76.3975 xenopus_tropicalis ENSXETP00000119399 80.719 80.3922 ENSG00000185129 homo_sapiens ENSP00000332706 81.0559 79.1925 chrysemys_picta_bellii ENSCPBP00000008365 88.7755 86.7347 ENSG00000185129 homo_sapiens ENSP00000332706 84.7826 80.7453 crocodylus_porosus ENSCPRP00005001294 82.2289 78.3133 ENSG00000185129 homo_sapiens ENSP00000332706 76.3975 73.6025 laticauda_laticaudata ENSLLTP00000023970 88.8087 85.5596 ENSG00000185129 homo_sapiens ENSP00000332706 86.0248 83.5404 notechis_scutatus ENSNSUP00000014693 86.8339 84.326 ENSG00000185129 homo_sapiens ENSP00000332706 84.7826 82.2981 pseudonaja_textilis ENSPTXP00000004561 86.6667 84.127 ENSG00000185129 homo_sapiens ENSP00000332706 86.0248 83.5404 gallus_gallus ENSGALP00010017303 84.7095 82.263 ENSG00000185129 homo_sapiens ENSP00000332706 59.0062 53.7267 parus_major ENSPMJP00000020282 55.7185 50.7331 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 neolamprologus_brichardi ENSNBRP00000007645 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 neolamprologus_brichardi ENSNBRP00000028038 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 86.0248 83.5404 naja_naja ENSNNAP00000013963 86.8339 84.326 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.8137 podarcis_muralis ENSPMRP00000019021 87.3754 85.3821 ENSG00000185129 homo_sapiens ENSP00000332706 59.3168 51.8634 geospiza_fortis ENSGFOP00000011799 58.589 51.227 ENSG00000185129 homo_sapiens ENSP00000332706 86.0248 83.8509 taeniopygia_guttata ENSTGUP00000001675 87.6582 85.443 ENSG00000185129 homo_sapiens ENSP00000332706 82.6087 80.4348 erpetoichthys_calabaricus ENSECRP00000033417 93.3333 90.8772 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.6025 kryptolebias_marmoratus ENSKMAP00000019074 88.6525 84.0426 ENSG00000185129 homo_sapiens ENSP00000332706 82.6087 80.1242 kryptolebias_marmoratus ENSKMAP00000030023 92.3611 89.5833 ENSG00000185129 homo_sapiens ENSP00000332706 85.4037 82.9193 salvator_merianae ENSSMRP00000024034 87.0253 84.4937 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.6708 oryzias_javanicus ENSOJAP00000006659 88.6121 83.274 ENSG00000185129 homo_sapiens ENSP00000332706 81.3665 78.882 oryzias_javanicus ENSOJAP00000011265 91.9298 89.1228 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.8137 amphilophus_citrinellus ENSACIP00000004263 87.9599 85.9532 ENSG00000185129 homo_sapiens ENSP00000332706 75.7764 71.4286 amphilophus_citrinellus ENSACIP00000006629 88.7273 83.6364 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 dicentrarchus_labrax ENSDLAP00005063850 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 dicentrarchus_labrax ENSDLAP00005066538 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 amphiprion_percula ENSAPEP00000011809 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 amphiprion_percula ENSAPEP00000034091 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 77.0186 74.5342 oryzias_sinensis ENSOSIP00000041872 96.124 93.0233 ENSG00000185129 homo_sapiens ENSP00000332706 76.7081 72.3602 oryzias_sinensis ENSOSIP00000033029 87.9004 82.9182 ENSG00000185129 homo_sapiens ENSP00000332706 85.0932 83.2298 gopherus_evgoodei ENSGEVP00005007595 89.8361 87.8689 ENSG00000185129 homo_sapiens ENSP00000332706 47.8261 40.9938 chelonoidis_abingdonii ENSCABP00000026322 38.8889 33.3333 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 seriola_dumerili ENSSDUP00000017972 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.5031 seriola_dumerili ENSSDUP00000007174 91.0035 88.5813 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.6708 cottoperca_gobio ENSCGOP00000020568 88.6121 83.274 ENSG00000185129 homo_sapiens ENSP00000332706 83.5404 79.8137 anser_brachyrhynchus ENSABRP00000016362 83.8006 80.0623 ENSG00000185129 homo_sapiens ENSP00000332706 72.3602 68.6335 gasterosteus_aculeatus ENSGACP00000024691 85.9779 81.5498 ENSG00000185129 homo_sapiens ENSP00000332706 81.0559 78.882 gasterosteus_aculeatus ENSGACP00000027318 89.3836 86.9863 ENSG00000185129 homo_sapiens ENSP00000332706 79.5031 77.0186 cynoglossus_semilaevis ENSCSEP00000014579 89.8246 87.0175 ENSG00000185129 homo_sapiens ENSP00000332706 76.087 72.9814 cynoglossus_semilaevis ENSCSEP00000026602 87.5 83.9286 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 poecilia_formosa ENSPFOP00000020009 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.9814 poecilia_formosa ENSPFOP00000020016 88.6121 83.6299 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 myripristis_murdjan ENSMMDP00005034674 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 myripristis_murdjan ENSMMDP00005031753 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.6025 sander_lucioperca ENSSLUP00000018929 88.968 84.3416 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.5031 sander_lucioperca ENSSLUP00000018892 92.2807 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 84.1615 82.2981 strigops_habroptila ENSSHBP00005012156 60.6264 59.2841 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 amphiprion_ocellaris ENSAOCP00000026335 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 amphiprion_ocellaris ENSAOCP00000022350 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 84.7826 82.9193 terrapene_carolina_triunguis ENSTMTP00000026856 89.5082 87.541 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.2919 hucho_hucho ENSHHUP00000055473 89.6429 84.2857 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.913 hucho_hucho ENSHHUP00000021381 89.6429 85 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.1925 hucho_hucho ENSHHUP00000048900 92.6316 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 hucho_hucho ENSHHUP00000040169 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 81.3665 78.882 betta_splendens ENSBSLP00000057282 91.9298 89.1228 ENSG00000185129 homo_sapiens ENSP00000332706 80.4348 77.6398 pygocentrus_nattereri ENSPNAP00000007474 90.5594 87.4126 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.6708 pygocentrus_nattereri ENSPNAP00000001960 89.2473 83.871 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 anabas_testudineus ENSATEP00000026754 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 anabas_testudineus ENSATEP00000028697 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 54.3478 39.1304 ciona_savignyi ENSCSAVP00000014193 60.5536 43.5986 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.5031 seriola_lalandi_dorsalis ENSSLDP00000023530 91.0035 88.5813 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 seriola_lalandi_dorsalis ENSSLDP00000030216 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 labrus_bergylta ENSLBEP00000006262 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.6025 labrus_bergylta ENSLBEP00000037894 88.968 84.3416 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 pundamilia_nyererei ENSPNYP00000000094 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 79.1925 77.3292 pundamilia_nyererei ENSPNYP00000018299 91.0714 88.9286 ENSG00000185129 homo_sapiens ENSP00000332706 76.3975 72.9814 mastacembelus_armatus ENSMAMP00000023026 84.8276 81.0345 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 mastacembelus_armatus ENSMAMP00000027169 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 stegastes_partitus ENSSPAP00000030452 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 stegastes_partitus ENSSPAP00000015967 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.2919 oncorhynchus_tshawytscha ENSOTSP00005073899 89.6429 84.2857 ENSG00000185129 homo_sapiens ENSP00000332706 77.9503 73.913 oncorhynchus_tshawytscha ENSOTSP00005079465 89.6429 85 ENSG00000185129 homo_sapiens ENSP00000332706 82.2981 79.8137 oncorhynchus_tshawytscha ENSOTSP00005089275 92.9825 90.1754 ENSG00000185129 homo_sapiens ENSP00000332706 82.2981 79.8137 oncorhynchus_tshawytscha ENSOTSP00005024019 92.9825 90.1754 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 acanthochromis_polyacanthus ENSAPOP00000006440 76.0116 73.6994 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 acanthochromis_polyacanthus ENSAPOP00000024913 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 47.205 40.0621 aquila_chrysaetos_chrysaetos ENSACCP00020012676 40 33.9474 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 nothobranchius_furzeri ENSNFUP00015045810 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.9814 cyprinodon_variegatus ENSCVAP00000030743 88.6121 83.6299 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 78.882 cyprinodon_variegatus ENSCVAP00000011563 92.6056 89.4366 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.9814 cyprinodon_variegatus ENSCVAP00000017333 88.6121 83.6299 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.8137 denticeps_clupeoides ENSDCDP00000043201 91.9861 89.547 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 larimichthys_crocea ENSLCRP00005015091 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 81.3665 78.882 larimichthys_crocea ENSLCRP00005026070 91.9298 89.1228 ENSG00000185129 homo_sapiens ENSP00000332706 78.882 76.7081 takifugu_rubripes ENSTRUP00000053085 89.4366 86.9718 ENSG00000185129 homo_sapiens ENSP00000332706 75.7764 71.7391 takifugu_rubripes ENSTRUP00000016680 88.0866 83.3935 ENSG00000185129 homo_sapiens ENSP00000332706 79.1925 77.9503 ficedula_albicollis ENSFALP00000015640 85.8586 84.5118 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 hippocampus_comes ENSHCOP00000003189 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 82.6087 77.3292 hippocampus_comes ENSHCOP00000016194 91.0959 85.274 ENSG00000185129 homo_sapiens ENSP00000332706 82.2981 79.8137 cyprinus_carpio_carpio ENSCCRP00000177315 92.3345 89.547 ENSG00000185129 homo_sapiens ENSP00000332706 77.0186 72.3602 cyprinus_carpio_carpio ENSCCRP00000167875 89.5307 84.1155 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 72.3602 cyprinus_carpio_carpio ENSCCRP00000004411 90.2527 84.1155 ENSG00000185129 homo_sapiens ENSP00000332706 82.9193 81.0559 cyprinus_carpio_carpio ENSCCRP00000129083 93.0314 90.9408 ENSG00000185129 homo_sapiens ENSP00000332706 86.646 82.6087 coturnix_japonica ENSCJPP00005014826 77.933 74.3017 ENSG00000185129 homo_sapiens ENSP00000332706 77.3292 72.9814 poecilia_latipinna ENSPLAP00000006002 88.6121 83.6299 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.5031 poecilia_latipinna ENSPLAP00000006372 92.6316 89.8246 ENSG00000185129 homo_sapiens ENSP00000332706 83.2298 80.7453 sinocyclocheilus_grahami ENSSGRP00000024102 78.3626 76.0234 ENSG00000185129 homo_sapiens ENSP00000332706 78.882 73.913 sinocyclocheilus_grahami ENSSGRP00000040671 88.5017 82.9268 ENSG00000185129 homo_sapiens ENSP00000332706 82.9193 81.0559 sinocyclocheilus_grahami ENSSGRP00000020618 93.0314 90.9408 ENSG00000185129 homo_sapiens ENSP00000332706 77.0186 72.0497 sinocyclocheilus_grahami ENSSGRP00000070403 88.2562 82.5623 ENSG00000185129 homo_sapiens ENSP00000332706 77.6398 73.2919 maylandia_zebra ENSMZEP00005007823 88.968 83.9858 ENSG00000185129 homo_sapiens ENSP00000332706 79.1925 77.3292 maylandia_zebra ENSMZEP00005024888 91.0714 88.9286 ENSG00000185129 homo_sapiens ENSP00000332706 80.1242 77.0186 tetraodon_nigroviridis ENSTNIP00000012900 92.1429 88.5714 ENSG00000185129 homo_sapiens ENSP00000332706 75.4658 71.4286 tetraodon_nigroviridis ENSTNIP00000007290 87.7256 83.0325 ENSG00000185129 homo_sapiens ENSP00000332706 80.7453 79.1925 paramormyrops_kingsleyae ENSPKIP00000003833 92.8571 91.0714 ENSG00000185129 homo_sapiens ENSP00000332706 74.8447 72.0497 paramormyrops_kingsleyae ENSPKIP00000015019 88.2784 84.9817 ENSG00000185129 homo_sapiens ENSP00000332706 79.5031 74.2236 scleropages_formosus ENSSFOP00015050220 89.8246 83.8596 ENSG00000185129 homo_sapiens ENSP00000332706 81.9876 79.8137 scleropages_formosus ENSSFOP00015049302 66.8354 65.0633 ENSG00000185129 homo_sapiens ENSP00000332706 78.882 77.9503 leptobrachium_leishanense ENSLLEP00000036678 92.029 90.942 ENSG00000185129 homo_sapiens ENSP00000332706 81.677 79.1925 scophthalmus_maximus ENSSMAP00000018910 92.2807 89.4737 ENSG00000185129 homo_sapiens ENSP00000332706 76.087 72.9814 scophthalmus_maximus ENSSMAP00000020962 86.5724 83.0389 ENSG00000185129 homo_sapiens ENSP00000332706 81.3665 78.882 oryzias_melastigma ENSOMEP00000018535 91.9298 89.1228 ENSG00000185129 homo_sapiens ENSP00000332706 75.7764 72.3602 oryzias_melastigma ENSOMEP00000014652 83.5616 79.7945
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000122 involved_in negative regulation of transcription by RNA polymerase II 1 IDA Homo_sapiens(9606) Process GO:0000781 located_in chromosome, telomeric region 1 IC Homo_sapiens(9606) Component GO:0000900 enables mRNA regulatory element binding translation repressor activity 1 IEA Homo_sapiens(9606) Function GO:0000977 enables RNA polymerase II transcription regulatory region sequence-specific DNA binding 1 IBA Homo_sapiens(9606) Function GO:0000981 enables DNA-binding transcription factor activity, RNA polymerase II-specific 1 IBA Homo_sapiens(9606) Function GO:0003691 enables double-stranded telomeric DNA binding 1 IDA Homo_sapiens(9606) Function GO:0003697 enables single-stranded DNA binding 1 ISS Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 2 IBA,IDA Homo_sapiens(9606) Component GO:0006268 involved_in DNA unwinding involved in DNA replication 1 IDA Homo_sapiens(9606) Process GO:0006270 involved_in DNA replication initiation 1 TAS Homo_sapiens(9606) Process GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 IBA Homo_sapiens(9606) Process GO:0007399 involved_in nervous system development 1 IEA Homo_sapiens(9606) Process GO:0008284 involved_in positive regulation of cell population proliferation 1 IEA Homo_sapiens(9606) Process GO:0017148 involved_in negative regulation of translation 1 IEA Homo_sapiens(9606) Process GO:0032422 enables purine-rich negative regulatory element binding 1 IBA Homo_sapiens(9606) Function GO:0032839 located_in dendrite cytoplasm 1 IEA Homo_sapiens(9606) Component GO:0043025 located_in neuronal cell body 1 IEA Homo_sapiens(9606) Component GO:0043433 involved_in negative regulation of DNA-binding transcription factor activity 1 IEA Homo_sapiens(9606) Process GO:0046332 enables SMAD binding 1 IEA Homo_sapiens(9606) Function GO:0046651 involved_in lymphocyte proliferation 1 IEA Homo_sapiens(9606) Process GO:0050673 involved_in epithelial cell proliferation 1 IEA Homo_sapiens(9606) Process GO:0098794 located_in postsynapse 1 IEA Homo_sapiens(9606) Component GO:0098963 involved_in dendritic transport of messenger ribonucleoprotein complex 1 IEA Homo_sapiens(9606) Process GO:0098978 located_in glutamatergic synapse 1 IEA Homo_sapiens(9606) Component GO:0140297 enables DNA-binding transcription factor binding 1 ISS Homo_sapiens(9606) Function GO:0140416 enables transcription regulator inhibitor activity 1 IEA Homo_sapiens(9606) Function
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