Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000180228 Gene ID 8575 Accession 9438
Symbol PRKRA Alias RAX;PACT;DYT16;HSD14 Full Name protein activator of interferon induced protein kinase EIF2AK2
Status Confidence Length 19987 bases Strand Minus strand
Position 2 : 178431292 - 178451278 RNA binding domain dsrm
Summary This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000430604 dsrm PF00035 7.6e-32 1
ENSP00000430604 dsrm PF00035 7.6e-32 2
ENSP00000393883 dsrm PF00035 9.5e-32 1
ENSP00000393883 dsrm PF00035 9.5e-32 2
ENSP00000318176 dsrm PF00035 1.1e-31 1
ENSP00000318176 dsrm PF00035 1.1e-31 2
ENSP00000504507 dsrm PF00035 6.5e-21 1
ENSP00000504507 dsrm PF00035 6.5e-21 2
ENSP00000503003 dsrm PF00035 1.2e-20 1
ENSP00000503003 dsrm PF00035 1.2e-20 2
ENSP00000503011 dsrm PF00035 7.3e-16 1
ENSP00000504030 dsrm PF00035 7.3e-16 1
ENSP00000502919 dsrm PF00035 1.2e-15 1
ENSP00000503536 dsrm PF00035 1.2e-15 1
ENSP00000503034 dsrm PF00035 4.5e-14 1
ENSP00000388455 dsrm PF00035 4.6e-14 1
ENSP00000408029 dsrm PF00035 5.8e-14 1
ENSP00000503466 dsrm PF00035 5.8e-14 1
ENSP00000504421 dsrm PF00035 6e-14 1
ENSP00000503369 dsrm PF00035 6e-14 1
ENSP00000504411 dsrm PF00035 6e-14 1
ENSP00000504479 dsrm PF00035 6e-14 1
ENSP00000408668 dsrm PF00035 1e-13 1
ENSP00000503203 dsrm PF00035 3.9e-10 1
ENSP00000504465 dsrm PF00035 1e-08 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37484321 PRKRA promotes pancreatic cancer progression by upregulating MMP1 transcription via the NF-κB pathway. Jiangdong Qiu 2023-06-01 Heliyon
35729579 The diagnostic and prognostic implications of PRKRA expression in HBV-related hepatocellular carcinoma. Yi-Min Hu 2022-06-21 Infectious agents and cancer
33459164 Identification of host factors binding to dengue and Zika virus subgenomic RNA by efficient yeast three-hybrid screens of the human ORFeome. Sander Jansen 2021-05-01 RNA biology

Transcripts

Name Transcript ID bp Protein Translation ID
PRKRA-226 ENST00000677859 1600 94aa ENSP00000504465
PRKRA-201 ENST00000325748 1770 313aa ENSP00000318176
PRKRA-212 ENST00000490501 1851 No protein -
PRKRA-218 ENST00000677136 3596 No protein -
PRKRA-210 ENST00000474793 1745 No protein -
PRKRA-214 ENST00000676586 3741 No protein -
PRKRA-204 ENST00000448279 1661 95aa ENSP00000388455
PRKRA-213 ENST00000676505 1793 43aa ENSP00000504163
PRKRA-219 ENST00000677206 1999 94aa ENSP00000503034
PRKRA-227 ENST00000677981 1455 229aa ENSP00000503536
PRKRA-234 ENST00000678845 1546 200aa ENSP00000503011
PRKRA-228 ENST00000678053 1645 54aa ENSP00000504330
PRKRA-235 ENST00000679037 1709 106aa ENSP00000504421
PRKRA-223 ENST00000677584 1885 106aa ENSP00000504411
PRKRA-216 ENST00000676832 1713 54aa ENSP00000503231
PRKRA-224 ENST00000677689 1610 228aa ENSP00000502919
PRKRA-217 ENST00000676922 1780 106aa ENSP00000503369
PRKRA-232 ENST00000678775 1738 200aa ENSP00000504030
PRKRA-215 ENST00000676752 3498 No protein -
PRKRA-236 ENST00000679202 2686 No protein -
PRKRA-229 ENST00000678058 1343 56aa ENSP00000503203
PRKRA-205 ENST00000457633 2103 127aa ENSP00000408668
PRKRA-220 ENST00000677253 1717 105aa ENSP00000503466
PRKRA-230 ENST00000678167 1587 106aa ENSP00000504479
PRKRA-221 ENST00000677386 1824 177aa ENSP00000503003
PRKRA-222 ENST00000677460 1752 191aa ENSP00000504507
PRKRA-202 ENST00000424699 1616 105aa ENSP00000408029
PRKRA-211 ENST00000487082 1211 288aa ENSP00000430604
PRKRA-203 ENST00000432031 1344 302aa ENSP00000393883
PRKRA-225 ENST00000677806 3890 No protein -
PRKRA-233 ENST00000678813 2209 No protein -
PRKRA-231 ENST00000678379 1621 No protein -
PRKRA-209 ENST00000470200 550 No protein -
PRKRA-206 ENST00000460433 461 No protein -
PRKRA-208 ENST00000466165 585 No protein -
PRKRA-207 ENST00000463882 541 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
83054Multiple Sclerosis3E-723472185
83056Oligoclonal Bands3E-723472185
105183Dermatitis, Atopic1E-3425574825
105185Psoriasis1E-3425574825

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000180228homo_sapiensENSP000004681816.792873.89755homo_sapiensENSP0000031817619.488811.1821
ENSG00000180228homo_sapiensENSP0000045750112.94824.98008homo_sapiensENSP0000031817620.76687.98722
ENSG00000180228homo_sapiensENSP000002650697.54194.28305homo_sapiensENSP0000031817625.878614.6965
ENSG00000180228homo_sapiensENSP000003213479.523815.20833homo_sapiensENSP0000031817620.447311.1821
ENSG00000180228homo_sapiensENSP0000035501116.66677.94872homo_sapiensENSP0000031817620.76689.90415
ENSG00000180228homo_sapiensENSP0000001587713.83747.41797homo_sapiensENSP0000031817630.990416.6134
ENSG00000180228homo_sapiensENSP000002629618.413214.47284homo_sapiensENSP0000031817625.239613.4185
ENSG00000180228homo_sapiensENSP0000032515313.55066.51801homo_sapiensENSP0000031817625.239612.1406
ENSG00000180228homo_sapiensENSP0000029651315.27786.94444homo_sapiensENSP0000031817628.11512.7796
ENSG00000180228homo_sapiensENSP0000036092213.69157.10572homo_sapiensENSP0000031817625.239613.099
ENSG00000180228homo_sapiensENSP0000037071313.80247.30717homo_sapiensENSP0000031817632.587917.2524
ENSG00000180228homo_sapiensENSP0000042875614.3868.94737homo_sapiensENSP0000031817626.198116.2939
ENSG00000180228homo_sapiensENSP000003574598.156614.48613homo_sapiensENSP0000031817631.948917.5719
ENSG00000180228homo_sapiensENSP0000026698751.366139.6175homo_sapiensENSP0000031817660.063946.3259

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000180228homo_sapiensENSP0000031817683.386683.3866pan_paniscusENSPPAP00000041383100100
ENSG00000180228homo_sapiensENSP0000031817683.067178.9137pongo_abeliiENSPPYP0000004095460.185257.1759
ENSG00000180228homo_sapiensENSP00000318176100100pan_troglodytesENSPTRP00000021685100100
ENSG00000180228homo_sapiensENSP0000031817610099.6805gorilla_gorillaENSGGOP0000000563610099.6805
ENSG00000180228homo_sapiensENSP0000031817678.594262.3003ornithorhynchus_anatinusENSOANP0000001375578.846262.5
ENSG00000180228homo_sapiensENSP0000031817688.498478.9137sarcophilus_harrisiiENSSHAP0000001157988.498478.9137
ENSG00000180228homo_sapiensENSP0000031817676.677369.6486notamacropus_eugeniiENSMEUP0000000239882.474274.9141
ENSG00000180228homo_sapiensENSP0000031817651.437751.1182choloepus_hoffmanniENSCHOP0000000916968.803468.3761
ENSG00000180228homo_sapiensENSP0000031817698.72298.4026dasypus_novemcinctusENSDNOP0000001527698.72298.4026
ENSG00000180228homo_sapiensENSP0000031817685.942584.345erinaceus_europaeusENSEEUP0000000042686.495284.8875
ENSG00000180228homo_sapiensENSP0000031817660.063958.7859echinops_telfairiENSETEP0000000841493.069391.0891
ENSG00000180228homo_sapiensENSP0000031817610099.6805callithrix_jacchusENSCJAP0000004007410099.6805
ENSG00000180228homo_sapiensENSP00000318176100100cercocebus_atysENSCATP00000017721100100
ENSG00000180228homo_sapiensENSP0000031817692.012892.0128macaca_fascicularisENSMFAP00000060856100100
ENSG00000180228homo_sapiensENSP0000031817687.220484.984macaca_mulattaENSMMUP0000007415188.636486.3636
ENSG00000180228homo_sapiensENSP0000031817651.757249.2013macaca_mulattaENSMMUP0000006531788.043583.6957
ENSG00000180228homo_sapiensENSP00000318176100100macaca_nemestrinaENSMNEP00000015097100100
ENSG00000180228homo_sapiensENSP00000318176100100papio_anubisENSPANP00000015117100100
ENSG00000180228homo_sapiensENSP0000031817692.012892.0128mandrillus_leucophaeusENSMLEP00000004333100100
ENSG00000180228homo_sapiensENSP0000031817683.067183.0671tursiops_truncatusENSTTRP0000000917199.616999.6169
ENSG00000180228homo_sapiensENSP0000031817694.249293.6102vulpes_vulpesENSVVUP0000001366397.682197.0199
ENSG00000180228homo_sapiensENSP0000031817699.36197.7636mus_spretusMGP_SPRETEiJ_P005450199.36197.7636
ENSG00000180228homo_sapiensENSP0000031817699.680599.361equus_asinusENSEASP0000503865499.680599.361
ENSG00000180228homo_sapiensENSP0000031817699.36197.7636capra_hircusENSCHIP0000001421699.36197.7636
ENSG00000180228homo_sapiensENSP0000031817676.677376.0383loxodonta_africanaENSLAFP0000002488198.360797.541
ENSG00000180228homo_sapiensENSP0000031817699.36199.0415panthera_leoENSPLOP0000002932499.36199.0415
ENSG00000180228homo_sapiensENSP0000031817699.680599.361ailuropoda_melanoleucaENSAMEP0000000085099.680599.361
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831bos_indicus_hybridENSBIXP0000502792799.36198.0831
ENSG00000180228homo_sapiensENSP0000031817698.72297.7636oryctolagus_cuniculusENSOCUP0000000476199.038598.0769
ENSG00000180228homo_sapiensENSP0000031817699.680599.361equus_caballusENSECAP0000008534799.680599.361
ENSG00000180228homo_sapiensENSP0000031817627.156526.5176canis_lupus_familiarisENSCAFP0084501233687.628985.567
ENSG00000180228homo_sapiensENSP0000031817699.680599.361canis_lupus_familiarisENSCAFP0084503093180.412480.1546
ENSG00000180228homo_sapiensENSP0000031817699.680599.361panthera_pardusENSPPRP0000002107999.680599.361
ENSG00000180228homo_sapiensENSP0000031817624.281221.4058panthera_pardusENSPPRP0000001228470.370462.037
ENSG00000180228homo_sapiensENSP0000031817695.527293.9297marmota_marmota_marmotaENSMMMP0000000743697.077995.4545
ENSG00000180228homo_sapiensENSP0000031817699.680599.0415balaenoptera_musculusENSBMSP0001000874599.680599.0415
ENSG00000180228homo_sapiensENSP0000031817699.36198.722cavia_porcellusENSCPOP0000000351999.36198.722
ENSG00000180228homo_sapiensENSP0000031817690.734888.4984cavia_porcellusENSCPOP0000001726894.666792.3333
ENSG00000180228homo_sapiensENSP0000031817699.680599.361felis_catusENSFCAP0000003716299.680599.361
ENSG00000180228homo_sapiensENSP0000031817632.907332.5879ursus_americanusENSUAMP0000001320397.169896.2264
ENSG00000180228homo_sapiensENSP0000031817688.817979.5527monodelphis_domesticaENSMODP0000001229788.817979.5527
ENSG00000180228homo_sapiensENSP0000031817693.929792.3323bison_bison_bisonENSBBBP0000001027397.35195.6954
ENSG00000180228homo_sapiensENSP0000031817699.680599.0415monodon_monocerosENSMMNP0001501907499.680599.0415
ENSG00000180228homo_sapiensENSP0000031817699.680599.361sus_scrofaENSSSCP0000003903199.680599.361
ENSG00000180228homo_sapiensENSP0000031817699.680599.361microcebus_murinusENSMICP0000002952699.680599.361
ENSG00000180228homo_sapiensENSP0000031817699.041598.722octodon_degusENSODEP0000001177899.041598.722
ENSG00000180228homo_sapiensENSP0000031817682.108679.2332octodon_degusENSODEP0000001063288.316285.2234
ENSG00000180228homo_sapiensENSP0000031817699.680598.0831jaculus_jaculusENSJJAP0000000901999.680598.0831
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831ovis_aries_rambouilletENSOARP0002002660899.36198.0831
ENSG00000180228homo_sapiensENSP0000031817692.012891.3738ursus_maritimusENSUMAP0000002265810099.3056
ENSG00000180228homo_sapiensENSP0000031817678.594276.9968ochotona_princepsENSOPRP0000000693979.099777.492
ENSG00000180228homo_sapiensENSP0000031817696.485693.9297delphinapterus_leucasENSDLEP0000002366491.515289.0909
ENSG00000180228homo_sapiensENSP0000031817699.680599.0415delphinapterus_leucasENSDLEP0000001330799.680599.0415
ENSG00000180228homo_sapiensENSP0000031817699.680599.0415physeter_catodonENSPCTP0000500567999.680599.0415
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831mus_caroliMGP_CAROLIEiJ_P005242099.36198.0831
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831mus_musculusENSMUSP0000000280899.36198.0831
ENSG00000180228homo_sapiensENSP0000031817699.041596.1661dipodomys_ordiiENSDORP0000001254099.041596.1661
ENSG00000180228homo_sapiensENSP0000031817699.680599.361mustela_putorius_furoENSMPUP0000000314799.680599.361
ENSG00000180228homo_sapiensENSP0000031817610099.361aotus_nancymaaeENSANAP0000000316310099.361
ENSG00000180228homo_sapiensENSP0000031817610099.361saimiri_boliviensis_boliviensisENSSBOP0000000239510099.361
ENSG00000180228homo_sapiensENSP0000031817681.469780.8307vicugna_pacosENSVPAP0000000322887.93187.2414
ENSG00000180228homo_sapiensENSP0000031817699.041597.4441tupaia_belangeriENSTBEP0000000557999.041597.4441
ENSG00000180228homo_sapiensENSP0000031817699.36198.722mesocricetus_auratusENSMAUP0000002208699.36198.722
ENSG00000180228homo_sapiensENSP0000031817699.36198.722phocoena_sinusENSPSNP0000000954299.36198.722
ENSG00000180228homo_sapiensENSP0000031817699.680599.0415camelus_dromedariusENSCDRP0000500426499.680599.0415
ENSG00000180228homo_sapiensENSP0000031817610099.6805carlito_syrichtaENSTSYP0000000890010099.6805
ENSG00000180228homo_sapiensENSP0000031817691.373891.0543panthera_tigris_altaicaENSPTIP0000000922091.373891.0543
ENSG00000180228homo_sapiensENSP0000031817699.680598.0831rattus_norvegicusENSRNOP0000001562499.680598.0831
ENSG00000180228homo_sapiensENSP0000031817610099.6805prolemur_simusENSPSMP0000000945810099.6805
ENSG00000180228homo_sapiensENSP0000031817698.72297.7636microtus_ochrogasterENSMOCP0000000512698.72297.7636
ENSG00000180228homo_sapiensENSP0000031817696.805195.8466sorex_araneusENSSARP0000000278796.805195.8466
ENSG00000180228homo_sapiensENSP0000031817699.041597.7636peromyscus_maniculatus_bairdiiENSPEMP0000001126199.041597.7636
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831bos_mutusENSBMUP0000001374699.36198.0831
ENSG00000180228homo_sapiensENSP0000031817699.680598.4026mus_spicilegusENSMSIP0000003534079.187878.1726
ENSG00000180228homo_sapiensENSP0000031817699.36198.4026cricetulus_griseus_chok1gshdENSCGRP0000100676178.93478.1726
ENSG00000180228homo_sapiensENSP0000031817689.137488.8179pteropus_vampyrusENSPVAP0000001651289.137488.8179
ENSG00000180228homo_sapiensENSP0000031817698.72297.4441myotis_lucifugusENSMLUP0000000531099.038597.7564
ENSG00000180228homo_sapiensENSP0000031817673.801969.6486myotis_lucifugusENSMLUP0000002095487.582.5758
ENSG00000180228homo_sapiensENSP0000031817688.178979.5527vombatus_ursinusENSVURP0001002449288.178979.5527
ENSG00000180228homo_sapiensENSP0000031817698.083197.4441rhinolophus_ferrumequinumENSRFEP0001003368963.561163.147
ENSG00000180228homo_sapiensENSP0000031817699.680599.361neovison_visonENSNVIP0000000801399.680599.361
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831bos_taurusENSBTAP0000000145199.36198.0831
ENSG00000180228homo_sapiensENSP0000031817690.734889.7764heterocephalus_glaber_femaleENSHGLP0000001491798.611197.5694
ENSG00000180228homo_sapiensENSP0000031817699.680599.6805rhinopithecus_bietiENSRBIP0000002270999.680599.6805
ENSG00000180228homo_sapiensENSP0000031817633.226833.2268canis_lupus_dingoENSCAFP0002000872898.113298.1132
ENSG00000180228homo_sapiensENSP0000031817610099.0415sciurus_vulgarisENSSVLP0000500623110099.0415
ENSG00000180228homo_sapiensENSP0000031817688.178979.5527phascolarctos_cinereusENSPCIP0000003429488.178979.5527
ENSG00000180228homo_sapiensENSP0000031817643.7743.131procavia_capensisENSPCAP0000000146557.322256.4854
ENSG00000180228homo_sapiensENSP0000031817699.041598.0831nannospalax_galiliENSNGAP0000002318699.041598.0831
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831bos_grunniensENSBGRP0000000122599.36198.0831
ENSG00000180228homo_sapiensENSP0000031817694.249293.6102chinchilla_lanigeraENSCLAP0000001499898.333397.6667
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831cervus_hanglu_yarkandensisENSCHYP0000003564799.36198.0831
ENSG00000180228homo_sapiensENSP0000031817699.680599.361catagonus_wagneriENSCWAP0000000177199.680599.361
ENSG00000180228homo_sapiensENSP0000031817699.680598.722ictidomys_tridecemlineatusENSSTOP0000000550499.680598.722
ENSG00000180228homo_sapiensENSP0000031817699.680599.0415otolemur_garnettiiENSOGAP0000001250699.680599.0415
ENSG00000180228homo_sapiensENSP0000031817610099.6805cebus_imitatorENSCCAP0000001322210099.6805
ENSG00000180228homo_sapiensENSP0000031817699.680598.722urocitellus_parryiiENSUPAP0001000729099.680598.722
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831moschus_moschiferusENSMMSP0000000761299.36198.0831
ENSG00000180228homo_sapiensENSP0000031817699.680599.6805rhinopithecus_roxellanaENSRROP0000002307099.680599.6805
ENSG00000180228homo_sapiensENSP0000031817699.36198.0831mus_pahariMGP_PahariEiJ_P006341399.36198.0831
ENSG00000180228homo_sapiensENSP0000031817610099.6805propithecus_coquereliENSPCOP0000001427010099.6805
ENSG00000180228homo_sapiensENSP0000031817628.75414.6965caenorhabditis_elegansY95B8A.8.111.78016.02094
ENSG00000180228homo_sapiensENSP0000031817622.044711.5016drosophila_melanogasterFBpp008007614.83877.74194
ENSG00000180228homo_sapiensENSP0000031817618.53048.6262drosophila_melanogasterFBpp007685617.90128.33333
ENSG00000180228homo_sapiensENSP0000031817617.25248.6262drosophila_melanogasterFBpp007321918.24329.12162
ENSG00000180228homo_sapiensENSP0000031817627.156514.6965drosophila_melanogasterFBpp03054899.615395.20362
ENSG00000180228homo_sapiensENSP0000031817624.600614.6965ciona_intestinalisENSCINP0000001280525.666715.3333
ENSG00000180228homo_sapiensENSP0000031817613.7385.43131ciona_intestinalisENSCINP0000003451811.52824.55764
ENSG00000180228homo_sapiensENSP0000031817621.086310.5431ciona_intestinalisENSCINP000000100466.969383.48469
ENSG00000180228homo_sapiensENSP0000031817622.044710.2236ciona_intestinalisENSCINP000000260428.273383.83693
ENSG00000180228homo_sapiensENSP0000031817667.412155.2716callorhinchus_miliiENSCMIP0000003217551.338242.0925
ENSG00000180228homo_sapiensENSP0000031817677.955363.2588latimeria_chalumnaeENSLACP0000000319678.205163.4615
ENSG00000180228homo_sapiensENSP0000031817670.287554.9521lepisosteus_oculatusENSLOCP0000000825571.895456.2092
ENSG00000180228homo_sapiensENSP0000031817663.578346.3259clupea_harengusENSCHAP0000005481362.187545.3125
ENSG00000180228homo_sapiensENSP0000031817661.341946.9649danio_rerioENSDARP0000003669768.085152.1277
ENSG00000180228homo_sapiensENSP0000031817661.341946.0064carassius_auratusENSCARP0000002840260.567845.4259
ENSG00000180228homo_sapiensENSP0000031817661.022444.4089carassius_auratusENSCARP0000000583258.769242.7692
ENSG00000180228homo_sapiensENSP0000031817663.258850.4792astyanax_mexicanusENSAMXP0000003640365.780752.4917
ENSG00000180228homo_sapiensENSP0000031817661.980848.8818ictalurus_punctatusENSIPUP0000002863466.211652.2184
ENSG00000180228homo_sapiensENSP0000031817662.300349.5208electrophorus_electricusENSEEEP0000002320161.320848.7421
ENSG00000180228homo_sapiensENSP0000031817668.370651.7572oncorhynchus_kisutchENSOKIP0000505651869.480552.5974
ENSG00000180228homo_sapiensENSP0000031817669.009653.0351oncorhynchus_kisutchENSOKIP0000507379770.129953.8961
ENSG00000180228homo_sapiensENSP0000031817668.370651.7572oncorhynchus_mykissENSOMYP0000006631469.480552.5974
ENSG00000180228homo_sapiensENSP0000031817669.009653.0351oncorhynchus_mykissENSOMYP0000005003570.129953.8961
ENSG00000180228homo_sapiensENSP0000031817668.370651.7572salmo_salarENSSSAP0000010156469.480552.5974
ENSG00000180228homo_sapiensENSP0000031817669.009653.0351salmo_salarENSSSAP0000008214270.129953.8961
ENSG00000180228homo_sapiensENSP0000031817668.370651.7572salmo_truttaENSSTUP0000010415969.480552.5974
ENSG00000180228homo_sapiensENSP0000031817669.009653.0351salmo_truttaENSSTUP0000009116370.129953.8961
ENSG00000180228homo_sapiensENSP0000031817656.549541.2141gadus_morhuaENSGMOP0000005579945.153132.9082
ENSG00000180228homo_sapiensENSP0000031817618.530411.8211fundulus_heteroclitusENSFHEP0000002516870.731745.122
ENSG00000180228homo_sapiensENSP0000031817665.814746.9649poecilia_reticulataENSPREP0000000830568.438548.8372
ENSG00000180228homo_sapiensENSP0000031817666.453747.2843xiphophorus_maculatusENSXMAP0000003271269.10349.1694
ENSG00000180228homo_sapiensENSP0000031817667.412150.7987oryzias_latipesENSORLP0000002201868.729651.7915
ENSG00000180228homo_sapiensENSP0000031817666.134248.8818cyclopterus_lumpusENSCLMP0000504372268.316850.495
ENSG00000180228homo_sapiensENSP0000031817667.092751.7572oreochromis_niloticusENSONIP000000107857054
ENSG00000180228homo_sapiensENSP0000031817667.092751.7572haplochromis_burtoniENSHBUP000000181117054
ENSG00000180228homo_sapiensENSP0000031817667.092751.7572astatotilapia_callipteraENSACLP000000122657054
ENSG00000180228homo_sapiensENSP0000031817667.092751.1182sparus_aurataENSSAUP0001005648763.444148.3384
ENSG00000180228homo_sapiensENSP0000031817668.051151.7572lates_calcariferENSLCAP0001003677669.381152.7687
ENSG00000180228homo_sapiensENSP0000031817652.396236.1022xenopus_tropicalisENSXETP0000008625759.205840.7942
ENSG00000180228homo_sapiensENSP0000031817673.482457.1885xenopus_tropicalisENSXETP0000009194873.717957.3718
ENSG00000180228homo_sapiensENSP0000031817679.872265.8147chrysemys_picta_belliiENSCPBP0000003124679.617865.6051
ENSG00000180228homo_sapiensENSP0000031817677.635863.2588sphenodon_punctatusENSSPUP0000000793670.028857.0605
ENSG00000180228homo_sapiensENSP0000031817674.760460.0639laticauda_laticaudataENSLLTP0000001236971.559657.4924
ENSG00000180228homo_sapiensENSP0000031817650.798743.131notechis_scutatusENSNSUP0000002152077.184565.534
ENSG00000180228homo_sapiensENSP0000031817622.044715.9744notechis_scutatusENSNSUP0000002151965.094347.1698
ENSG00000180228homo_sapiensENSP0000031817674.440960.7029pseudonaja_textilisENSPTXP0000000489170.606157.5758
ENSG00000180228homo_sapiensENSP0000031817676.996861.3419anolis_carolinensisENSACAP0000001696565.311752.0325
ENSG00000180228homo_sapiensENSP0000031817667.412152.3962neolamprologus_brichardiENSNBRP0000001399070.333354.6667
ENSG00000180228homo_sapiensENSP0000031817674.440960.3834naja_najaENSNNAP0000000010270.606157.2727
ENSG00000180228homo_sapiensENSP0000031817625.239618.8498podarcis_muralisENSPMRP0000000497675.238156.1905
ENSG00000180228homo_sapiensENSP0000031817662.939347.2843erpetoichthys_calabaricusENSECRP0000001050568.881151.7483
ENSG00000180228homo_sapiensENSP0000031817664.536750.1597kryptolebias_marmoratusENSKMAP0000002181166.447451.6447
ENSG00000180228homo_sapiensENSP0000031817676.677361.9808salvator_merianaeENSSMRP0000002349464.864952.4324
ENSG00000180228homo_sapiensENSP0000031817668.370652.0767oryzias_javanicusENSOJAP0000004736969.255752.7508
ENSG00000180228homo_sapiensENSP0000031817660.702947.6038amphilophus_citrinellusENSACIP0000002600671.428656.015
ENSG00000180228homo_sapiensENSP0000031817667.731651.1182amphiprion_perculaENSAPEP0000003205669.96752.8053
ENSG00000180228homo_sapiensENSP0000031817646.964937.0607oryzias_sinensisENSOSIP0000001176669.339654.717
ENSG00000180228homo_sapiensENSP0000031817676.038363.2588pelodiscus_sinensisENSPSIP0000000293682.352968.5121
ENSG00000180228homo_sapiensENSP0000031817674.440960.3834gopherus_evgoodeiENSGEVP0000502716171.253857.7982
ENSG00000180228homo_sapiensENSP0000031817676.677362.6198chelonoidis_abingdoniiENSCABP0000002515883.04567.8201
ENSG00000180228homo_sapiensENSP0000031817668.370651.7572seriola_dumeriliENSSDUP0000000075969.706852.7687
ENSG00000180228homo_sapiensENSP0000031817667.731651.4377cottoperca_gobioENSCGOP0000001590269.055452.443
ENSG00000180228homo_sapiensENSP0000031817666.134250.4792gasterosteus_aculeatusENSGACP0000000581568.54352.3179
ENSG00000180228homo_sapiensENSP0000031817667.092749.5208cynoglossus_semilaevisENSCSEP0000000454661.764745.5882
ENSG00000180228homo_sapiensENSP0000031817665.495247.6038poecilia_formosaENSPFOP0000001505767.656849.1749
ENSG00000180228homo_sapiensENSP0000031817667.412150.7987myripristis_murdjanENSMMDP0000504621568.729651.7915
ENSG00000180228homo_sapiensENSP0000031817665.814750.4792sander_luciopercaENSSLUP0000001859167.10151.4658
ENSG00000180228homo_sapiensENSP0000031817662.619847.9233amphiprion_ocellarisENSAOCP0000000516676.264658.3658
ENSG00000180228homo_sapiensENSP0000031817679.872265.8147terrapene_carolina_triunguisENSTMTP0000002368379.617865.6051
ENSG00000180228homo_sapiensENSP0000031817668.370651.7572hucho_huchoENSHHUP0000005785269.480552.5974
ENSG00000180228homo_sapiensENSP0000031817669.009653.0351hucho_huchoENSHHUP0000007757070.129953.8961
ENSG00000180228homo_sapiensENSP0000031817664.856248.2428betta_splendensENSBSLP0000005577770.731752.6132
ENSG00000180228homo_sapiensENSP0000031817660.702947.9233pygocentrus_nattereriENSPNAP0000003336969.597154.9451
ENSG00000180228homo_sapiensENSP0000031817668.370652.3962anabas_testudineusENSATEP0000002165069.706853.4202
ENSG00000180228homo_sapiensENSP000003181764.792331.59744ciona_savignyiENSCSAVP000000032666.072872.02429
ENSG00000180228homo_sapiensENSP000003181764.472842.23642ciona_savignyiENSCSAVP000000115296.666673.33333
ENSG00000180228homo_sapiensENSP0000031817662.619848.5623seriola_lalandi_dorsalisENSSLDP0000000077567.586252.4138
ENSG00000180228homo_sapiensENSP0000031817666.134251.4377labrus_bergyltaENSLBEP0000002242167.426752.443
ENSG00000180228homo_sapiensENSP0000031817666.773251.4377pundamilia_nyerereiENSPNYP0000001159469.666753.6667
ENSG00000180228homo_sapiensENSP0000031817668.690151.1182mastacembelus_armatusENSMAMP0000000977170.032652.1173
ENSG00000180228homo_sapiensENSP0000031817668.051150.7987stegastes_partitusENSSPAP0000002794369.381151.7915
ENSG00000180228homo_sapiensENSP0000031817668.370651.7572oncorhynchus_tshawytschaENSOTSP0000510224969.480552.5974
ENSG00000180228homo_sapiensENSP0000031817669.009653.0351oncorhynchus_tshawytschaENSOTSP0000509588770.129953.8961
ENSG00000180228homo_sapiensENSP0000031817667.092751.4377acanthochromis_polyacanthusENSAPOP0000003212369.306953.1353
ENSG00000180228homo_sapiensENSP0000031817661.980846.6454nothobranchius_furzeriENSNFUP0001504334464.238448.3444
ENSG00000180228homo_sapiensENSP0000031817665.495247.2843cyprinodon_variegatusENSCVAP0000000173468.106349.1694
ENSG00000180228homo_sapiensENSP0000031817665.495248.5623denticeps_clupeoidesENSDCDP0000006127766.775249.5114
ENSG00000180228homo_sapiensENSP0000031817667.731651.1182larimichthys_croceaENSLCRP0000505669768.167251.4469
ENSG00000180228homo_sapiensENSP0000031817665.814747.6038takifugu_rubripesENSTRUP0000005219562.424245.1515
ENSG00000180228homo_sapiensENSP0000031817662.939346.9649hippocampus_comesENSHCOP0000000403964.379148.0392
ENSG00000180228homo_sapiensENSP0000031817661.980846.6454cyprinus_carpio_carpioENSCCRP0000011586160.248445.3416
ENSG00000180228homo_sapiensENSP0000031817661.341946.6454cyprinus_carpio_carpioENSCCRP000000483286045.625
ENSG00000180228homo_sapiensENSP0000031817665.175747.2843poecilia_latipinnaENSPLAP0000001736367.774149.1694
ENSG00000180228homo_sapiensENSP0000031817661.022445.6869sinocyclocheilus_grahamiENSSGRP0000008729566.0949.481
ENSG00000180228homo_sapiensENSP0000031817659.744446.0064sinocyclocheilus_grahamiENSSGRP0000003481466.785751.4286
ENSG00000180228homo_sapiensENSP0000031817657.188540.5751maylandia_zebraENSMZEP0000500576561.724143.7931
ENSG00000180228homo_sapiensENSP0000031817665.495248.2428tetraodon_nigroviridisENSTNIP0000002008567.434249.6711
ENSG00000180228homo_sapiensENSP0000031817665.814751.1182paramormyrops_kingsleyaeENSPKIP0000000585067.10152.1173
ENSG00000180228homo_sapiensENSP0000031817664.856247.2843scleropages_formosusENSSFOP0001500328866.123848.2085
ENSG00000180228homo_sapiensENSP0000031817672.52457.508leptobrachium_leishanenseENSLLEP0000004598372.29357.3248
ENSG00000180228homo_sapiensENSP0000031817665.814749.8403scophthalmus_maximusENSSMAP0000005919962.61447.4164
ENSG00000180228homo_sapiensENSP0000031817668.051152.0767oryzias_melastigmaENSOMEP0000000422068.93252.7508

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003725enables double-stranded RNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006468involved_in protein phosphorylation1IEAHomo_sapiens(9606)Process
GO:0006955involved_in immune response1TASHomo_sapiens(9606)Process
GO:0008047enables enzyme activator activity1TASHomo_sapiens(9606)Function
GO:0008285involved_in negative regulation of cell population proliferation1TASHomo_sapiens(9606)Process
GO:0009615involved_in response to virus1TASHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016442part_of RISC complex1IBAHomo_sapiens(9606)Component
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0030422involved_in siRNA processing2IBA,IDAHomo_sapiens(9606)Process
GO:0031054involved_in pre-miRNA processing1IDAHomo_sapiens(9606)Process
GO:0034599involved_in cellular response to oxidative stress1IEAHomo_sapiens(9606)Process
GO:0035196involved_in miRNA processing1IDAHomo_sapiens(9606)Process
GO:0035197enables siRNA binding1IBAHomo_sapiens(9606)Function
GO:0042473involved_in outer ear morphogenesis1IEAHomo_sapiens(9606)Process
GO:0042474involved_in middle ear morphogenesis1IEAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0042803enables protein homodimerization activity1IPIHomo_sapiens(9606)Function
GO:0048471located_in perinuclear region of cytoplasm1IEAHomo_sapiens(9606)Component
GO:0048705involved_in skeletal system morphogenesis1IEAHomo_sapiens(9606)Process
GO:0050821involved_in protein stabilization1IMPHomo_sapiens(9606)Process
GO:0070578part_of RISC-loading complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0070883enables pre-miRNA binding1IDAHomo_sapiens(9606)Function
GO:0070920involved_in regulation of regulatory ncRNA processing1IBAHomo_sapiens(9606)Process
GO:2001244involved_in positive regulation of intrinsic apoptotic signaling pathway1IEAHomo_sapiens(9606)Process

Expression