Ensembl ID ENSG00000180228 Gene ID 8575 Accession 9438
Gene Symbol PRKRA Alias RAX;PACT;DYT16;HSD14 Full Name protein activator of interferon induced protein kinase EIF2AK2
Position 2 : 178431292 - 178451278 Length 19987 bases Strand Minus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

ENSG00000180228 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000180228 PRKRA adrenocortical tumors 23671264
ENSG00000180228 PRKRA colon cancer 27107574
ENSG00000180228 PRKRA Mucinous Ovarian Cancer 30305341
ENSG00000180228 PRKRA cancer 31494269
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000180228 PRKRA SARC 0.014 low
ENSG00000180228 PRKRA PAAD 0.046 high
ENSG00000180228 PRKRA UCEC 0.0032 high
ENSG00000180228 PRKRA THCA 0.034 low
ENSG00000180228 PRKRA LGG 0.0054 low
ENSG00000180228 PRKRA LUSC 0.029 low
ENSG00000180228 PRKRA HNSC 0.028 high
ENSG00000180228 PRKRA KIRP 0.016 high
ENSG00000180228 PRKRA KICH 0.0055 high
ENSG00000180228 PRKRA LUAD 0.014 high
ENSG00000180228 PRKRA PCPG 0.00058 high
ENSG00000180228 PRKRA COAD 0.026 high
ENSG00000180228 PRKRA OV 0.0018 low
ENSG00000180228 PRKRA KIRC 0.044 high
ENSG00000180228 PRKRA PRAD 0.049 low
ENSG00000180228 PRKRA TGCT 0.00055 high
ENSG00000180228 PRKRA BLCA 0.038 high
ENSG00000180228 PRKRA LAML 0.0012 low
ENSG00000180228 PRKRA CESC 0.033 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000180228 PRKRA LUSC Amp 1.089928 0.207403 0.466877 0.329341
ENSG00000180228 PRKRA CESC Amp 0.729217 0.129370 0.586621 0.138983
ENSG00000180228 PRKRA KIRP Amp 1.259300 0.077488 0.649775 0.184028
ENSG00000180228 PRKRA HNSC Amp 2.450074 0.156894 0.477663 0.208812
ENSG00000180228 PRKRA PRAD Del 0.901061 0.074817 0.404472 0.109756
ENSG00000180228 PRKRA OV Amp 3.149355 0.407131 0.621223 0.426598