RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000178999	Gene ID	9212	Accession	11390
Symbol	AURKB	Alias	AIK2;AIM1;ARK2;AurB;IPL1;STK5;AIM-1;ARK-2;STK-1;STK12;PPP1R48;aurkb-sv1;aurkb-sv2	Full Name	aurora kinase B
Status	Confidence	Length	5852 bases	Strand	Minus strand
Position	17 : 8204733 - 8210584	RNA binding domain	N.A.
Summary	This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Protein	Domain	Pfam ID	E-value	Domain number
No data available in table

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hela_human	Hela	Alfredo Castello	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
29431736	RICK_PMID29431736_Hela_human	Hela	Xichen Bao	2018 Mar	doi: 10.1038/nmeth.4595.?Epub 2018 Feb 12
29636419	CARIC_PMID29636419_Hela_human	Hela	Xichen Bao	2018 Apr 24	doi: 10.1073/pnas.1718406115.?Epub 2018 Apr 10
30352994	eRIC_PMID30352994_Jurkat_human	Jurkat	Joel I Perez-Perri?	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30824702	PtexRIC_PMID30824702_293T_human	293T	Erika C Urdaneta	2019 Mar 1	doi: 10.1038/s41467-019-08942-3
33332543	FAX.RIC_PMID33332543_Hela_human	Hela	Yongwoo Na	2021 Mar 18	doi: 10.1093/nar/gkaa1194
33693821	PP.enrichment.RIC_PMID33693821_Hela_human	Hela	Zheng Zhang	2021 Jun 21	doi: 10.1093/nar/gkab156
35451177	PhotoCAX.MS_PMID35451177_293T_human	293T	Huixin Luo	2022 Jul 4	doi: 10.1002/anie.202202008
35848924	RIC_PMID35848924_human		Neus Mestre-Farras	2022 Aug 12	doi: 10.1093/nar/gkac605
37421941	RIC_PMID37421941_Hydra10_human		Wenhao Jin	2023 Jul 20	doi: 10.1016/j.molcel.2023.06.019.?Epub 2023 Jul 7

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Literatures on RNA binding capacity

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Pubmed ID	Title	Author	Time	Journal
19704020	AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome.	L Lisa Hall	2009-08-24	The Journal of cell biology
21447818	XIST RNA and architecture of the inactive X chromosome: implications for the repeat genome.	L L Hall	2010-01-01	Cold Spring Harbor symposia on quantitative biology
33127860	PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells.	Nikenza Viceconte	2021-01-01	RNA (New York, N.Y.)

Showing 1 to 3 of 3 entries

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Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
AURKB-201	ENST00000316199	1254	345aa	ENSP00000313950
AURKB-202	ENST00000534871	1167	303aa	ENSP00000443869
AURKB-203	ENST00000577833	867	230aa	ENSP00000463636
AURKB-204	ENST00000578549	939	312aa	ENSP00000462207
AURKB-205	ENST00000578753	467	No protein	-
AURKB-206	ENST00000580390	740	No protein	-
AURKB-207	ENST00000580998	746	123aa	ENSP00000461981
AURKB-208	ENST00000581511	742	228aa	ENSP00000462930
AURKB-209	ENST00000582368	771	172aa	ENSP00000464031
AURKB-210	ENST00000583124	323	No protein	-

Showing 1 to 10 of 14 entries

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Gene Model

Click here to download ENSG00000178999's gene model file

ensgID	Trait	pValue	Pubmed ID
No data available in table

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
No data available in table

Protein-Protein Interaction (PPI)

Click here to download ENSG00000178999's PPI file

Paralogs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
No data available in table

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
No data available in table

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0004674	enables protein serine/threonine kinase activity	4	EXP,IDA,TAS	Homo_sapiens(9606)	Function
GO:0000776	is_active_in kinetochore	3	IBA,IDA	Homo_sapiens(9606)	Component
GO:0032133	part_of chromosome passenger complex	3	IBA,IPI,TAS	Homo_sapiens(9606)	Component
GO:0051256	involved_in mitotic spindle midzone assembly	3	IMP,NAS,TAS	Homo_sapiens(9606)	Process
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0006468	involved_in protein phosphorylation	2	IDA,NAS	Homo_sapiens(9606)	Process
GO:0007052	involved_in mitotic spindle organization	2	IBA,NAS	Homo_sapiens(9606)	Process
GO:0030496	located_in midbody	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0032467	involved_in positive regulation of cytokinesis	2	IMP,TAS	Homo_sapiens(9606)	Process
GO:0000122	involved_in negative regulation of transcription by RNA polymerase II	1	IDA	Homo_sapiens(9606)	Process

Showing 1 to 10 of 58 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression