RBPWorld - a comprehensive database of RNA Binding Proteins

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Drugs target to AURKB

Drug name	Drug type	Disease/phenotype	Mechanism of action(MoA)	Phase	Status	Source
IBCASERTIB	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	3	['Completed', 'Recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Terminated']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
AT-9283	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	2	['Completed', 'Completed', 'Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TAK-901	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	1	['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TOZASERTIB	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	2	['Terminated', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Terminated', 'Terminated']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
GSK-1070916	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	1	['Completed']	['ClinicalTrials']
BARASERTIB	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	2	['Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
ILORASERTIB	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	2	['Completed', 'Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TTP-607	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	1	['Withdrawn', 'Withdrawn']	['ClinicalTrials', 'ClinicalTrials']
DANUSERTIB	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	2	['Completed', 'Unknown status', 'Terminated']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
BI-811283	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	2	['Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials']
MK-6592	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	1	['Terminated']	['ClinicalTrials']
SNS-314	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	1	['Completed']	['ClinicalTrials']
AMG-900	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	1	['Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials']
ENMD-2076	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	2	['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed']	['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
CENISERTIB	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	1	['Terminated', 'Completed']	['ClinicalTrials', 'ClinicalTrials']
CYC-116	Small molecule	none	Serine/threonine-protein kinase Aurora inhibitor	1	['Terminated']	['ClinicalTrials']
PF-03814735	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	1	['Completed']	['ClinicalTrials']
KW-2449	Small molecule	none	Serine/threonine-protein kinase Aurora-B inhibitor	1	['Terminated']	['ClinicalTrials']