Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions KinaseTransmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000178607 Gene ID 2081 Accession 3449
Symbol ERN1 Alias IRE1;IRE1P;IRE1a;hIRE1p Full Name endoplasmic reticulum to nucleus signaling 1
Status Confidence Length 91740 bases Strand Minus strand
Position 17 : 64039080 - 64130819 RNA binding domain Ribonuc_2-5A
Summary This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. [provided by RefSeq, Aug 2017]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000401445 Ribonuc_2-5A PF06479 9.8e-40 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ERN1-208 ENST00000680433 9028 905aa ENSP00000506094
ERN1-201 ENST00000433197 7895 977aa ENSP00000401445
ERN1-210 ENST00000680625 7687 No protein -
ERN1-204 ENST00000583077 503 No protein -
ERN1-205 ENST00000583896 571 No protein -
ERN1-203 ENST00000579249 548 No protein -
ERN1-202 ENST00000577567 398 No protein -
ERN1-206 ENST00000584041 566 No protein -
ERN1-209 ENST00000680493 4833 96aa ENSP00000505990
ERN1-207 ENST00000606895 4717 70aa ENSP00000475519

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
16092Stroke6.6206780E-00419369658

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000178607homo_sapiensENSP0000025679763.282951.0799homo_sapiensENSP0000040144559.979548.4135

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000178607homo_sapiensENSP0000040144510099.2835nomascus_leucogenysENSNLEP0000001833310099.2835
ENSG00000178607homo_sapiensENSP0000040144599.692999.6929pan_paniscusENSPPAP0000001588399.692999.6929
ENSG00000178607homo_sapiensENSP0000040144599.692999.4882pongo_abeliiENSPPYP0000000959499.795199.5902
ENSG00000178607homo_sapiensENSP0000040144599.795399.7953pan_troglodytesENSPTRP0000008022499.795399.7953
ENSG00000178607homo_sapiensENSP0000040144599.795399.5906gorilla_gorillaENSGGOP0000000639899.795399.5906
ENSG00000178607homo_sapiensENSP0000040144590.788185.1586sarcophilus_harrisiiENSSHAP0000001659790.510284.898
ENSG00000178607homo_sapiensENSP0000040144573.797369.0891notamacropus_eugeniiENSMEUP0000000741574.17769.4444
ENSG00000178607homo_sapiensENSP0000040144557.011355.0665choloepus_hoffmanniENSCHOP0000001134966.786664.5084
ENSG00000178607homo_sapiensENSP0000040144595.291792.4258dasypus_novemcinctusENSDNOP0000000735595.389392.5205
ENSG00000178607homo_sapiensENSP0000040144578.198674.5138erinaceus_europaeusENSEEUP0000000562080.167976.3903
ENSG00000178607homo_sapiensENSP0000040144588.126984.3398echinops_telfairiENSETEP0000000341486.186282.4825
ENSG00000178607homo_sapiensENSP0000040144598.2697.7482callithrix_jacchusENSCJAP0000005371198.059297.5485
ENSG00000178607homo_sapiensENSP0000040144599.590698.8741cercocebus_atysENSCATP0000003596499.590698.8741
ENSG00000178607homo_sapiensENSP0000040144599.488298.567macaca_fascicularisENSMFAP0000004281199.386598.4663
ENSG00000178607homo_sapiensENSP0000040144599.488298.7718macaca_mulattaENSMMUP0000001991499.386598.6708
ENSG00000178607homo_sapiensENSP0000040144599.488298.567macaca_nemestrinaENSMNEP0000004330799.386598.4663
ENSG00000178607homo_sapiensENSP0000040144599.795399.0788papio_anubisENSPANP0000004245899.795399.0788
ENSG00000178607homo_sapiensENSP0000040144597.850697.1341mandrillus_leucophaeusENSMLEP0000001906899.687298.9572
ENSG00000178607homo_sapiensENSP0000040144589.662287.7175tursiops_truncatusENSTTRP0000000662790.965788.9927
ENSG00000178607homo_sapiensENSP0000040144596.110594.1658vulpes_vulpesENSVVUP0000000824994.752892.8355
ENSG00000178607homo_sapiensENSP0000040144596.008292.8352mus_spretusMGP_SPRETEiJ_P003201696.008292.8352
ENSG00000178607homo_sapiensENSP0000040144597.441195.7011equus_asinusENSEASP0000502116792.697291.0419
ENSG00000178607homo_sapiensENSP0000040144594.472992.2211capra_hircusENSCHIP0000003155396.649294.3456
ENSG00000178607homo_sapiensENSP0000040144594.984693.4493loxodonta_africanaENSLAFP0000000713997.172895.6021
ENSG00000178607homo_sapiensENSP0000040144596.5294.7799panthera_leoENSPLOP0000001862197.016595.2675
ENSG00000178607homo_sapiensENSP0000040144595.701194.0635ailuropoda_melanoleucaENSAMEP0000000303295.897494.2564
ENSG00000178607homo_sapiensENSP0000040144595.803593.8587bos_indicus_hybridENSBIXP0000503714196.098694.1478
ENSG00000178607homo_sapiensENSP0000040144594.165891.1975equus_caballusENSECAP0000006593991.179488.3053
ENSG00000178607homo_sapiensENSP0000040144597.236495.2917canis_lupus_familiarisENSCAFP0084503097497.435995.4872
ENSG00000178607homo_sapiensENSP0000040144596.315394.5752panthera_pardusENSPPRP0000001747196.810795.0617
ENSG00000178607homo_sapiensENSP0000040144596.110594.2682marmota_marmota_marmotaENSMMMP0000001157698.221896.3389
ENSG00000178607homo_sapiensENSP0000040144596.008294.2682balaenoptera_musculusENSBMSP0001003002394.747593.0303
ENSG00000178607homo_sapiensENSP0000040144596.5294.0635cavia_porcellusENSCPOP0000000050196.817294.3532
ENSG00000178607homo_sapiensENSP0000040144596.622394.7799felis_catusENSFCAP0000000323697.119395.2675
ENSG00000178607homo_sapiensENSP0000040144594.677692.4258ursus_americanusENSUAMP0000000889794.580892.3313
ENSG00000178607homo_sapiensENSP0000040144595.496493.4493bison_bison_bisonENSBBBP0000000570995.790693.7372
ENSG00000178607homo_sapiensENSP0000040144595.598893.654monodon_monocerosENSMMNP0001502881395.794993.8462
ENSG00000178607homo_sapiensENSP0000040144596.110593.4493sus_scrofaENSSSCP0000007187396.505793.8335
ENSG00000178607homo_sapiensENSP0000040144597.441195.4964microcebus_murinusENSMICP0000000916797.741395.7906
ENSG00000178607homo_sapiensENSP0000040144594.779992.0164octodon_degusENSODEP0000001038495.071992.2998
ENSG00000178607homo_sapiensENSP0000040144540.327539.7134jaculus_jaculusENSJJAP0000001195696.805995.3317
ENSG00000178607homo_sapiensENSP0000040144595.701193.2446ovis_aries_rambouilletENSOARP0002001928596.193493.7243
ENSG00000178607homo_sapiensENSP0000040144592.016490.4811ursus_maritimusENSUMAP0000002421687.366485.9086
ENSG00000178607homo_sapiensENSP0000040144593.039990.6858ochotona_princepsENSOPRP0000000744594.392592.0042
ENSG00000178607homo_sapiensENSP0000040144594.882392.6305delphinapterus_leucasENSDLEP0000000875595.076992.8205
ENSG00000178607homo_sapiensENSP0000040144588.638786.2845physeter_catodonENSPCTP0000502583393.018390.5478
ENSG00000178607homo_sapiensENSP0000040144596.008292.7329mus_caroliMGP_CAROLIEiJ_P003057296.008292.7329
ENSG00000178607homo_sapiensENSP0000040144596.008292.8352mus_musculusENSMUSP0000000105996.008292.8352
ENSG00000178607homo_sapiensENSP0000040144540.429940.0205dipodomys_ordiiENSDORP0000000140497.290696.3054
ENSG00000178607homo_sapiensENSP0000040144596.82794.7799mustela_putorius_furoENSMPUP0000001466197.025694.9744
ENSG00000178607homo_sapiensENSP0000040144597.441196.6223aotus_nancymaaeENSANAP0000000340094.071193.2806
ENSG00000178607homo_sapiensENSP0000040144595.496494.8823saimiri_boliviensis_boliviensisENSSBOP0000003888896.784296.1618
ENSG00000178607homo_sapiensENSP0000040144538.280437.564vicugna_pacosENSVPAP0000001001249.933248.9987
ENSG00000178607homo_sapiensENSP0000040144599.385998.567chlorocebus_sabaeusENSCSAP0000000035399.385998.567
ENSG00000178607homo_sapiensENSP0000040144571.238569.3961tupaia_belangeriENSTBEP0000000400284.46682.2816
ENSG00000178607homo_sapiensENSP0000040144536.745136.2334mesocricetus_auratusENSMAUP0000002525196.246794.9062
ENSG00000178607homo_sapiensENSP0000040144595.496493.4493phocoena_sinusENSPSNP0000002554895.692393.641
ENSG00000178607homo_sapiensENSP0000040144595.905893.8587camelus_dromedariusENSCDRP0000503060296.102694.0513
ENSG00000178607homo_sapiensENSP0000040144591.60786.1822carlito_syrichtaENSTSYP0000002190894.309888.725
ENSG00000178607homo_sapiensENSP0000040144595.394193.654panthera_tigris_altaicaENSPTIP0000000013595.589793.8462
ENSG00000178607homo_sapiensENSP0000040144595.803593.1423rattus_norvegicusENSRNOP0000007224495.803593.1423
ENSG00000178607homo_sapiensENSP0000040144597.236495.2917prolemur_simusENSPSMP0000001717197.435995.4872
ENSG00000178607homo_sapiensENSP0000040144595.08792.2211microtus_ochrogasterENSMOCP0000000470895.773292.8866
ENSG00000178607homo_sapiensENSP0000040144595.905893.2446peromyscus_maniculatus_bairdiiENSPEMP0000000228095.905893.2446
ENSG00000178607homo_sapiensENSP0000040144594.677692.6305bos_mutusENSBMUP0000001112096.757394.6653
ENSG00000178607homo_sapiensENSP0000040144596.008292.8352mus_spicilegusENSMSIP0000002949596.008292.8352
ENSG00000178607homo_sapiensENSP0000040144596.008293.347cricetulus_griseus_chok1gshdENSCGRP0000100281096.008293.347
ENSG00000178607homo_sapiensENSP0000040144593.244691.1975pteropus_vampyrusENSPVAP0000000045493.820891.7611
ENSG00000178607homo_sapiensENSP0000040144595.598892.9376myotis_lucifugusENSMLUP0000001525995.893293.2238
ENSG00000178607homo_sapiensENSP0000040144590.17484.7492vombatus_ursinusENSVURP0001001363190.451785.0103
ENSG00000178607homo_sapiensENSP0000040144597.031794.9846rhinolophus_ferrumequinumENSRFEP0001002303697.330695.2772
ENSG00000178607homo_sapiensENSP0000040144594.677692.6305neovison_visonENSNVIP0000003075494.677692.6305
ENSG00000178607homo_sapiensENSP0000040144595.803593.8587bos_taurusENSBTAP000000223479694.0513
ENSG00000178607homo_sapiensENSP0000040144562.43659.7748heterocephalus_glaber_femaleENSHGLP0000001427794.867890.8243
ENSG00000178607homo_sapiensENSP0000040144598.362397.4411rhinopithecus_bietiENSRBIP0000001822098.061297.1429
ENSG00000178607homo_sapiensENSP0000040144596.110594.0635canis_lupus_dingoENSCAFP0002003427895.233393.2049
ENSG00000178607homo_sapiensENSP0000040144597.543595.087sciurus_vulgarisENSSVLP0000500156697.643495.1844
ENSG00000178607homo_sapiensENSP0000040144590.378785.1586phascolarctos_cinereusENSPCIP0000000675490.10284.898
ENSG00000178607homo_sapiensENSP0000040144572.569170.7267procavia_capensisENSPCAP0000001527177.656175.6846
ENSG00000178607homo_sapiensENSP0000040144596.212993.9611nannospalax_galiliENSNGAP0000001926796.212993.9611
ENSG00000178607homo_sapiensENSP0000040144596.008293.9611bos_grunniensENSBGRP0000001861896.303994.2505
ENSG00000178607homo_sapiensENSP0000040144584.749282.088chinchilla_lanigeraENSCLAP0000000998196.055793.0394
ENSG00000178607homo_sapiensENSP0000040144595.701193.5517cervus_hanglu_yarkandensisENSCHYP0000001978595.995993.8398
ENSG00000178607homo_sapiensENSP0000040144596.315394.1658catagonus_wagneriENSCWAP0000002712196.910494.7477
ENSG00000178607homo_sapiensENSP0000040144597.134195.2917ictidomys_tridecemlineatusENSSTOP0000000813997.633795.7819
ENSG00000178607homo_sapiensENSP0000040144589.866988.2293otolemur_garnettiiENSOGAP0000000343697.231595.4596
ENSG00000178607homo_sapiensENSP0000040144593.244691.5046cebus_imitatorENSCCAP0000003368294.208992.4509
ENSG00000178607homo_sapiensENSP0000040144597.543595.5988urocitellus_parryiiENSUPAP0001000175497.743695.7949
ENSG00000178607homo_sapiensENSP0000040144594.984692.6305moschus_moschiferusENSMMSP0000002927295.867893.4917
ENSG00000178607homo_sapiensENSP0000040144598.464797.5435rhinopithecus_roxellanaENSRROP0000000431598.163397.2449
ENSG00000178607homo_sapiensENSP0000040144595.803592.4258mus_pahariMGP_PahariEiJ_P003729295.803592.4258
ENSG00000178607homo_sapiensENSP0000040144593.142391.4023propithecus_coquereliENSPCOP0000002288797.326295.508
ENSG00000178607homo_sapiensENSP0000040144511.15669.00716ciona_intestinalisENSCINP0000003493561.931850
ENSG00000178607homo_sapiensENSP0000040144530.603926.6121eptatretus_burgeriENSEBUP0000000473077.461167.3575
ENSG00000178607homo_sapiensENSP0000040144578.505668.2702callorhinchus_miliiENSCMIP0000004910679.646969.2627
ENSG00000178607homo_sapiensENSP0000040144584.032874.1044latimeria_chalumnaeENSLACP0000001825285.878775.7322
ENSG00000178607homo_sapiensENSP0000040144585.056374.7185lepisosteus_oculatusENSLOCP0000001691285.056374.7185
ENSG00000178607homo_sapiensENSP0000040144571.136163.2549salmo_salarENSSSAP0000001121960.121153.4602
ENSG00000178607homo_sapiensENSP0000040144583.82874.7185xenopus_tropicalisENSXETP0000011552284.086274.9487
ENSG00000178607homo_sapiensENSP0000040144586.796379.4268chrysemys_picta_belliiENSCPBP0000001211185.570178.3047
ENSG00000178607homo_sapiensENSP0000040144584.339877.4821sphenodon_punctatusENSSPUP0000000644888.41281.2232
ENSG00000178607homo_sapiensENSP0000040144588.638781.0645crocodylus_porosusENSCPRP0000500228289.278481.6495
ENSG00000178607homo_sapiensENSP0000040144573.490366.1208laticauda_laticaudataENSLLTP0000002125687.241878.4933
ENSG00000178607homo_sapiensENSP0000040144585.568177.5844notechis_scutatusENSNSUP0000001186587.907579.7056
ENSG00000178607homo_sapiensENSP0000040144585.568177.6868pseudonaja_textilisENSPTXP0000000866487.174179.1449
ENSG00000178607homo_sapiensENSP0000040144588.126980.4504anas_platyrhynchos_platyrhynchosENSAPLP0000000750889.874782.0459
ENSG00000178607homo_sapiensENSP0000040144587.615280.1433gallus_gallusENSGALP0001004428688.888981.3084
ENSG00000178607homo_sapiensENSP0000040144587.922280.4504meleagris_gallopavoENSMGAP0000000801084.71477.5148
ENSG00000178607homo_sapiensENSP0000040144587.410479.9386serinus_canariaENSSCAP0000001947386.965479.5316
ENSG00000178607homo_sapiensENSP0000040144587.717581.1668parus_majorENSPMJP0000002409089.177982.5182
ENSG00000178607homo_sapiensENSP0000040144587.00178.5056anolis_carolinensisENSACAP0000001648887.179578.6667
ENSG00000178607homo_sapiensENSP0000040144586.69478.8127naja_najaENSNNAP0000000170187.590579.6277
ENSG00000178607homo_sapiensENSP0000040144587.205779.2221podarcis_muralisENSPMRP0000000400186.761778.8187
ENSG00000178607homo_sapiensENSP0000040144583.213976.3562geospiza_fortisENSGFOP0000001540289.636282.2492
ENSG00000178607homo_sapiensENSP0000040144588.024681.3715taeniopygia_guttataENSTGUP0000000491788.751382.0433
ENSG00000178607homo_sapiensENSP0000040144583.930472.8762erpetoichthys_calabaricusENSECRP0000002645684.362173.251
ENSG00000178607homo_sapiensENSP0000040144586.898778.3009salvator_merianaeENSSMRP0000000606688.714779.9373
ENSG00000178607homo_sapiensENSP0000040144585.568177.8915pelodiscus_sinensisENSPSIP0000001957287.356379.5193
ENSG00000178607homo_sapiensENSP0000040144585.158678.3009gopherus_evgoodeiENSGEVP0000502111187.578980.5263
ENSG00000178607homo_sapiensENSP0000040144584.851677.8915chelonoidis_abingdoniiENSCABP0000000627187.263280.1053
ENSG00000178607homo_sapiensENSP0000040144587.922280.9621struthio_camelus_australisENSSCUP0000001580088.923481.8841
ENSG00000178607homo_sapiensENSP0000040144588.945881.2692anser_brachyrhynchusENSABRP0000001100589.865682.1096
ENSG00000178607homo_sapiensENSP0000040144588.43481.1668strigops_habroptilaENSSHBP0000502530787.272780.101
ENSG00000178607homo_sapiensENSP0000040144587.103479.8362terrapene_carolina_triunguisENSTMTP0000000856888.186580.829
ENSG00000178607homo_sapiensENSP0000040144534.800424.1556hucho_huchoENSHHUP0000008451863.909844.3609
ENSG00000178607homo_sapiensENSP0000040144522.722618.1167hucho_huchoENSHHUP0000007821174.247559.1973
ENSG00000178607homo_sapiensENSP0000040144558.137243.3982ciona_savignyiENSCSAVP0000001779061.339145.7883
ENSG00000178607homo_sapiensENSP0000040144575.844465.9161oncorhynchus_tshawytschaENSOTSP0000503184378.082267.8609
ENSG00000178607homo_sapiensENSP0000040144588.536381.6786aquila_chrysaetos_chrysaetosENSACCP0002000821488.900382.0144
ENSG00000178607homo_sapiensENSP0000040144587.410480.1433ficedula_albicollisENSFALP0000003141988.314480.9721
ENSG00000178607homo_sapiensENSP0000040144587.512879.6315coturnix_japonicaENSCJPP0000502760488.053680.1236
ENSG00000178607homo_sapiensENSP0000040144583.52172.262scleropages_formosusENSSFOP0001500871082.674871.5299
ENSG00000178607homo_sapiensENSP0000040144584.442275.6397leptobrachium_leishanenseENSLLEP0000004672387.301678.2011

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000287enables magnesium ion binding1IDAHomo_sapiens(9606)Function
GO:0001935involved_in endothelial cell proliferation1IDAHomo_sapiens(9606)Process
GO:0004521enables RNA endonuclease activity2IBA,IDAHomo_sapiens(9606)Function
GO:0004674enables protein serine/threonine kinase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005161enables platelet-derived growth factor receptor binding1IPIHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IDAHomo_sapiens(9606)Function
GO:0005637located_in nuclear inner membrane1IEAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IEAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005789located_in endoplasmic reticulum membrane2IDA,TASHomo_sapiens(9606)Component
GO:0006402involved_in mRNA catabolic process1TASHomo_sapiens(9606)Process
GO:0006468involved_in protein phosphorylation1IDAHomo_sapiens(9606)Process
GO:0016241involved_in regulation of macroautophagy1TASHomo_sapiens(9606)Process
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0030544enables Hsp70 protein binding1IPIHomo_sapiens(9606)Function
GO:0033120involved_in positive regulation of RNA splicing1IDAHomo_sapiens(9606)Process
GO:0034620involved_in cellular response to unfolded protein2IDA,IMPHomo_sapiens(9606)Process
GO:0034976involved_in response to endoplasmic reticulum stress1IDAHomo_sapiens(9606)Process
GO:0035924involved_in cellular response to vascular endothelial growth factor stimulus1IDAHomo_sapiens(9606)Process
GO:0036289involved_in peptidyl-serine autophosphorylation1IDAHomo_sapiens(9606)Process
GO:0036498involved_in IRE1-mediated unfolded protein response3IBA,IDA,IMPHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0042803enables protein homodimerization activity3IDA,IPI,ISSHomo_sapiens(9606)Function
GO:0043507involved_in positive regulation of JUN kinase activity1IDAHomo_sapiens(9606)Process
GO:0043531enables ADP binding1IDAHomo_sapiens(9606)Function
GO:0046777involved_in protein autophosphorylation1IDAHomo_sapiens(9606)Process
GO:0051082enables unfolded protein binding1IBAHomo_sapiens(9606)Function
GO:0051879enables Hsp90 protein binding1IDAHomo_sapiens(9606)Function
GO:0070054involved_in mRNA splicing, via endonucleolytic cleavage and ligation3IDA,IMP,TASHomo_sapiens(9606)Process
GO:0070059involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2IBA,ISSHomo_sapiens(9606)Process
GO:0070301involved_in cellular response to hydrogen peroxide1IEAHomo_sapiens(9606)Process
GO:0071333involved_in cellular response to glucose stimulus1IDAHomo_sapiens(9606)Process
GO:0106310enables protein serine kinase activity1IEAHomo_sapiens(9606)Function
GO:1900103involved_in positive regulation of endoplasmic reticulum unfolded protein response1IMPHomo_sapiens(9606)Process
GO:1901142involved_in insulin metabolic process1IDAHomo_sapiens(9606)Process
GO:1904707involved_in positive regulation of vascular associated smooth muscle cell proliferation1IMPHomo_sapiens(9606)Process
GO:1990332part_of Ire1 complex1NASHomo_sapiens(9606)Component
GO:1990579involved_in peptidyl-serine trans-autophosphorylation1IMPHomo_sapiens(9606)Process
GO:1990597part_of AIP1-IRE1 complex1IEAHomo_sapiens(9606)Component
GO:1990604part_of IRE1-TRAF2-ASK1 complex2IBA,IDAHomo_sapiens(9606)Component
GO:1990630part_of IRE1-RACK1-PP2A complex1IDAHomo_sapiens(9606)Component

Expression