RBP Type	Non-canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000178035	Gene ID	3615	Accession	6053
Symbol	IMPDH2	Alias	IMPD2;IMPDH-II	Full Name	inosine monophosphate dehydrogenase 2
Status	Confidence	Length	5102 bases	Strand	Minus strand
Position	3 : 49024325 - 49029426	RNA binding domain	N.A.
Summary	This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]