RBP Type	Non-canonical_RBPs
Diseases	CancerDengue
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000177885	Gene ID	2885	Accession	4566
Symbol	GRB2	Alias	ASH;Grb3-3;MST084;NCKAP2;MSTP084;EGFRBP-GRB2	Full Name	growth factor receptor bound protein 2
Status	Confidence	Length	87634 bases	Strand	Minus strand
Position	17 : 75318076 - 75405709	RNA binding domain	N.A.
Summary	The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]