RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	CancerDengue
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000177885	Gene ID	2885	Accession	4566
Symbol	GRB2	Alias	ASH;Grb3-3;MST084;NCKAP2;MSTP084;EGFRBP-GRB2	Full Name	growth factor receptor bound protein 2
Status	Confidence	Length	87634 bases	Strand	Minus strand
Position	17 : 75318076 - 75405709	RNA binding domain	N.A.
Summary	The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
32174881	A Moderate Blast Exposure Results in Dysregulated Gene Network Activity Related to Cell Death, Survival, Structure, and Metabolism.	A Katie Edwards	2020-01-01	Frontiers in neurology
36173161	Saturation mutagenesis of a predicted ancestral Syk-family kinase.	T Helen Hobbs	2022-10-01	Protein science : a publication of the Protein Society
34345012	NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization.	Jiachun Su	2021-09-01	Oncogene
23826330	A Novel Phosphopeptide Microarray Based Interactome Map in Breast Cancer Cells Reveals Phosphoprotein-GRB2 Cell Signaling Networks.	Srinivasan Krishnamoorthy	2013-01-01	PloS one
37328606	Regulation of microRNA expression by the adaptor protein GRB2.	K Amy Stainthorp	2023-06-16	Scientific reports
21930784	A novel phospholipase D2-Grb2-WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism.	Samuel Kantonen	2011-11-01	Molecular and cellular biology

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
GRB2-209	ENST00000581959	359	42aa	ENSP00000463525
GRB2-204	ENST00000392563	2851	176aa	ENSP00000376346
GRB2-205	ENST00000392564	3182	217aa	ENSP00000376347
GRB2-203	ENST00000392562	3729	217aa	ENSP00000376345
GRB2-202	ENST00000316804	3273	217aa	ENSP00000339007
GRB2-201	ENST00000316615	3181	176aa	ENSP00000317360
GRB2-212	ENST00000648046	1711	217aa	ENSP00000496913
GRB2-208	ENST00000578961	687	156aa	ENSP00000464279
GRB2-206	ENST00000462266	601	No protein	-
GRB2-210	ENST00000582582	584	110aa	ENSP00000462785
GRB2-211	ENST00000583912	561	No protein	-
GRB2-207	ENST00000577711	555	No protein	-

Gene Model

Click here to download ENSG00000177885's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
12079	Neuroblastoma	1.1E-6	18463370
62518	Lupus Erythematosus, Systemic	3E-6	26502338

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000177885's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000177885	homo_sapiens	ENSP00000423602	30	15.7143	homo_sapiens	ENSP00000339007	38.7097	20.2765
ENSG00000177885	homo_sapiens	ENSP00000406026	20.331	12.2931	homo_sapiens	ENSP00000339007	39.6313	23.9631
ENSG00000177885	homo_sapiens	ENSP00000339186	47.2727	33.0303	homo_sapiens	ENSP00000339007	71.8894	50.2304
ENSG00000177885	homo_sapiens	ENSP00000284154	76.9585	58.9862	homo_sapiens	ENSP00000339007	76.9585	58.9862
ENSG00000177885	homo_sapiens	ENSP00000437409	72.0339	57.6271	homo_sapiens	ENSP00000339007	39.1705	31.3364
ENSG00000177885	homo_sapiens	ENSP00000337548	32.971	17.3913	homo_sapiens	ENSP00000339007	41.9355	22.1198
ENSG00000177885	homo_sapiens	ENSP00000417273	27.321	16.1804	homo_sapiens	ENSP00000339007	47.4654	28.1106
ENSG00000177885	homo_sapiens	ENSP00000233154	26.3158	14.4737	homo_sapiens	ENSP00000339007	46.083	25.3456
ENSG00000177885	homo_sapiens	ENSP00000262866	37.5479	19.5402	homo_sapiens	ENSP00000339007	45.1613	23.5023

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	nomascus_leucogenys	ENSNLEP00000040743	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	pan_paniscus	ENSPPAP00000009849	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	pongo_abelii	ENSPPYP00000009686	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	pan_troglodytes	ENSPTRP00000016382	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	gorilla_gorilla	ENSGGOP00000005990	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	90.7834	88.0184	ornithorhynchus_anatinus	ENSOANP00000013236	96.5686	93.6274
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	98.1567	sarcophilus_harrisii	ENSSHAP00000034196	99.0783	98.1567
ENSG00000177885	homo_sapiens	ENSP00000339007	83.4101	80.6452	notamacropus_eugenii	ENSMEUP00000014379	83.4101	80.6452
ENSG00000177885	homo_sapiens	ENSP00000339007	82.0276	82.0276	choloepus_hoffmanni	ENSCHOP00000006543	82.7907	82.7907
ENSG00000177885	homo_sapiens	ENSP00000339007	89.4009	88.4793	dasypus_novemcinctus	ENSDNOP00000009933	100	98.9691
ENSG00000177885	homo_sapiens	ENSP00000339007	99.5392	98.6175	dasypus_novemcinctus	ENSDNOP00000021051	99.5392	98.6175
ENSG00000177885	homo_sapiens	ENSP00000339007	73.7327	73.7327	erinaceus_europaeus	ENSEEUP00000001559	73.7327	73.7327
ENSG00000177885	homo_sapiens	ENSP00000339007	70.0461	69.5853	echinops_telfairi	ENSETEP00000004442	70.0461	69.5853
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	callithrix_jacchus	ENSCJAP00000067776	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	cercocebus_atys	ENSCATP00000042750	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	macaca_fascicularis	ENSMFAP00000063617	99.0868	99.0868
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	macaca_mulatta	ENSMMUP00000045339	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	macaca_nemestrina	ENSMNEP00000026946	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	papio_anubis	ENSPANP00000016119	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	99.5392	mandrillus_leucophaeus	ENSMLEP00000017678	100	99.5392
ENSG00000177885	homo_sapiens	ENSP00000339007	71.8894	71.8894	tursiops_truncatus	ENSTTRP00000013678	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	92.6267	91.2442	vulpes_vulpes	ENSVVUP00000015427	57.265	56.4103
ENSG00000177885	homo_sapiens	ENSP00000339007	100	99.5392	mus_spretus	MGP_SPRETEiJ_P0032430	100	99.5392
ENSG00000177885	homo_sapiens	ENSP00000339007	93.5484	93.5484	equus_asinus	ENSEASP00005060315	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	capra_hircus	ENSCHIP00000015407	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	98.6175	loxodonta_africana	ENSLAFP00000004965	100	98.6175
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	panthera_leo	ENSPLOP00000020057	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	ailuropoda_melanoleuca	ENSAMEP00000024190	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	bos_indicus_hybrid	ENSBIXP00005000194	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	92.6267	90.7834	oryctolagus_cuniculus	ENSOCUP00000042433	72.3022	70.8633
ENSG00000177885	homo_sapiens	ENSP00000339007	99.5392	99.5392	equus_caballus	ENSECAP00000050303	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	canis_lupus_familiaris	ENSCAFP00845037253	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	panthera_pardus	ENSPPRP00000010296	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	marmota_marmota_marmota	ENSMMMP00000011990	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	balaenoptera_musculus	ENSBMSP00010019885	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	cavia_porcellus	ENSCPOP00000031642	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	felis_catus	ENSFCAP00000023767	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	93.5484	93.5484	ursus_americanus	ENSUAMP00000012687	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.6959	monodelphis_domestica	ENSMODP00000009105	99.0783	97.6959
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	bison_bison_bison	ENSBBBP00000026192	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	monodon_monoceros	ENSMMNP00015029103	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	sus_scrofa	ENSSSCP00000018229	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	microcebus_murinus	ENSMICP00000024881	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	octodon_degus	ENSODEP00000013691	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	90.7834	89.4009	octodon_degus	ENSODEP00000000012	93.3649	91.9431
ENSG00000177885	homo_sapiens	ENSP00000339007	90.7834	88.4793	jaculus_jaculus	ENSJJAP00000006302	93.3649	90.9953
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	ovis_aries_rambouillet	ENSOARP00020007929	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	ursus_maritimus	ENSUMAP00000011527	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	ochotona_princeps	ENSOPRP00000011345	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	delphinapterus_leucas	ENSDLEP00000010462	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	56.2212	55.2995	physeter_catodon	ENSPCTP00005031830	89.7059	88.2353
ENSG00000177885	homo_sapiens	ENSP00000339007	100	99.5392	mus_caroli	MGP_CAROLIEiJ_P0030989	100	99.5392
ENSG00000177885	homo_sapiens	ENSP00000339007	100	99.5392	mus_musculus	ENSMUSP00000021090	100	99.5392
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	dipodomys_ordii	ENSDORP00000027785	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	mustela_putorius_furo	ENSMPUP00000013779	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	aotus_nancymaae	ENSANAP00000005271	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	84.7926	84.3318	saimiri_boliviensis_boliviensis	ENSSBOP00000034988	100	99.4565
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	vicugna_pacos	ENSVPAP00000011029	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	chlorocebus_sabaeus	ENSCSAP00000001067	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	99.5392	99.5392	tupaia_belangeri	ENSTBEP00000013618	99.5392	99.5392
ENSG00000177885	homo_sapiens	ENSP00000339007	100	99.5392	mesocricetus_auratus	ENSMAUP00000018342	100	99.5392
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	phocoena_sinus	ENSPSNP00000027084	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	camelus_dromedarius	ENSCDRP00005009646	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	carlito_syrichta	ENSTSYP00000033033	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	panthera_tigris_altaica	ENSPTIP00000020872	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	98.6175	98.6175	rattus_norvegicus	ENSRNOP00000005347	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	prolemur_simus	ENSPSMP00000000205	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	microtus_ochrogaster	ENSMOCP00000019593	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	84.7926	84.3318	sorex_araneus	ENSSARP00000010403	84.7926	84.3318
ENSG00000177885	homo_sapiens	ENSP00000339007	100	99.0783	peromyscus_maniculatus_bairdii	ENSPEMP00000035271	100	99.0783
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	bos_mutus	ENSBMUP00000011430	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	99.5392	mus_spicilegus	ENSMSIP00000033809	100	99.5392
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	cricetulus_griseus_chok1gshd	ENSCGRP00001017434	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	pteropus_vampyrus	ENSPVAP00000007969	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	myotis_lucifugus	ENSMLUP00000013902	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	98.1567	vombatus_ursinus	ENSVURP00010015476	99.0783	98.1567
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	rhinolophus_ferrumequinum	ENSRFEP00010019250	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	neovison_vison	ENSNVIP00000013678	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	bos_taurus	ENSBTAP00000006216	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	heterocephalus_glaber_female	ENSHGLP00000008128	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	rhinopithecus_bieti	ENSRBIP00000016424	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	canis_lupus_dingo	ENSCAFP00020000209	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	sciurus_vulgaris	ENSSVLP00005007552	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	91.2442	88.0184	phascolarctos_cinereus	ENSPCIP00000049493	69.7183	67.2535
ENSG00000177885	homo_sapiens	ENSP00000339007	88.0184	87.0968	procavia_capensis	ENSPCAP00000011361	100	98.9529
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	nannospalax_galili	ENSNGAP00000016444	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	92.1659	90.3226	bos_grunniens	ENSBGRP00000028741	49.0196	48.0392
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	chinchilla_lanigera	ENSCLAP00000004147	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	92.1659	90.7834	cervus_hanglu_yarkandensis	ENSCHYP00000003569	59.7015	58.806
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	catagonus_wagneri	ENSCWAP00000024375	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	ictidomys_tridecemlineatus	ENSSTOP00000011345	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	otolemur_garnettii	ENSOGAP00000002746	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	cebus_imitator	ENSCCAP00000027991	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	urocitellus_parryii	ENSUPAP00010030565	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	moschus_moschiferus	ENSMMSP00000017730	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	rhinopithecus_roxellana	ENSRROP00000034137	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	100	99.5392	mus_pahari	MGP_PahariEiJ_P0037712	100	99.5392
ENSG00000177885	homo_sapiens	ENSP00000339007	100	100	propithecus_coquereli	ENSPCOP00000017791	100	100
ENSG00000177885	homo_sapiens	ENSP00000339007	73.7327	58.0645	caenorhabditis_elegans	C14F5.5.1	70.1754	55.2632
ENSG00000177885	homo_sapiens	ENSP00000339007	76.0369	63.5945	drosophila_melanogaster	FBpp0086817	78.1991	65.4028
ENSG00000177885	homo_sapiens	ENSP00000339007	76.0369	62.212	ciona_intestinalis	ENSCINP00000033135	71.4286	58.4416
ENSG00000177885	homo_sapiens	ENSP00000339007	52.5346	43.318	ciona_intestinalis	ENSCINP00000001039	75	61.8421
ENSG00000177885	homo_sapiens	ENSP00000339007	93.5484	85.2535	petromyzon_marinus	ENSPMAP00000009227	92.2727	84.0909
ENSG00000177885	homo_sapiens	ENSP00000339007	65.8986	58.5253	eptatretus_burgeri	ENSEBUP00000013885	89.375	79.375
ENSG00000177885	homo_sapiens	ENSP00000339007	88.4793	85.7143	callorhinchus_milii	ENSCMIP00000043216	78.0488	75.6098
ENSG00000177885	homo_sapiens	ENSP00000339007	91.2442	87.0968	latimeria_chalumnae	ENSLACP00000000662	67.8082	64.726
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	lepisosteus_oculatus	ENSLOCP00000016401	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	98.6175	94.47	clupea_harengus	ENSCHAP00000007381	98.6175	94.47
ENSG00000177885	homo_sapiens	ENSP00000339007	98.6175	94.9309	danio_rerio	ENSDARP00000122829	98.6175	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	94.47	carassius_auratus	ENSCARP00000061532	98.1567	94.47
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	carassius_auratus	ENSCARP00000002342	97.2477	93.578
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	94.0092	astyanax_mexicanus	ENSAMXP00000038603	98.1567	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	94.9309	ictalurus_punctatus	ENSIPUP00000012121	98.1567	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.3917	esox_lucius	ENSELUP00000008949	98.1567	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	87.0968	84.7926	electrophorus_electricus	ENSEEEP00000041421	93.1034	90.6404
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	95.3917	oncorhynchus_kisutch	ENSOKIP00005034978	97.6959	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	88.9401	86.1751	oncorhynchus_kisutch	ENSOKIP00005044029	80.083	77.5934
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	95.3917	oncorhynchus_mykiss	ENSOMYP00000063729	97.6959	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.9309	oncorhynchus_mykiss	ENSOMYP00000051118	97.6959	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	94.9309	salmo_salar	ENSSSAP00000000574	97.235	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	94.9309	salmo_salar	ENSSSAP00000010856	94.6188	92.3767
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	95.3917	salmo_trutta	ENSSTUP00000011011	97.6959	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	95.3917	salmo_trutta	ENSSTUP00000031342	97.6959	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	93.5484	gadus_morhua	ENSGMOP00000069124	97.6959	93.5484
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	fundulus_heteroclitus	ENSFHEP00000027392	97.6959	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	94.47	poecilia_reticulata	ENSPREP00000022510	98.1567	94.47
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	xiphophorus_maculatus	ENSXMAP00000004986	97.6959	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	93.5484	oryzias_latipes	ENSORLP00000019097	97.2477	93.1193
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.3917	cyclopterus_lumpus	ENSCLMP00005034531	98.1567	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	60.3687	50.2304	oreochromis_niloticus	ENSONIP00000064237	59.009	49.0991
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	91.2442	haplochromis_burtoni	ENSHBUP00000034295	97.235	91.2442
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	91.2442	astatotilapia_calliptera	ENSACLP00000027361	97.235	91.2442
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.47	sparus_aurata	ENSSAUP00010005726	96.3636	93.1818
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	lates_calcarifer	ENSLCAP00010000204	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	96.7742	xenopus_tropicalis	ENSXETP00000118282	93.0131	91.7031
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	96.7742	chrysemys_picta_bellii	ENSCPBP00000040946	99.0783	96.7742
ENSG00000177885	homo_sapiens	ENSP00000339007	85.2535	81.106	sphenodon_punctatus	ENSSPUP00000012045	87.6777	83.4123
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.6959	crocodylus_porosus	ENSCPRP00005005681	99.0783	97.6959
ENSG00000177885	homo_sapiens	ENSP00000339007	89.4009	86.6359	laticauda_laticaudata	ENSLLTP00000011575	94.1748	91.2621
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	96.3134	notechis_scutatus	ENSNSUP00000019343	99.0783	96.3134
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	96.3134	pseudonaja_textilis	ENSPTXP00000002950	99.0783	96.3134
ENSG00000177885	homo_sapiens	ENSP00000339007	89.4009	87.5576	anas_platyrhynchos_platyrhynchos	ENSAPLP00000031733	95.5665	93.5961
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.6959	gallus_gallus	ENSGALP00010044539	89.9582	88.7029
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.6959	meleagris_gallopavo	ENSMGAP00000009787	99.0783	97.6959
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	96.7742	serinus_canaria	ENSSCAP00000001089	76.6187	75.5396
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	96.7742	parus_major	ENSPMJP00000000661	64.939	64.0244
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.235	anolis_carolinensis	ENSACAP00000006419	99.0783	97.235
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	91.2442	neolamprologus_brichardi	ENSNBRP00000000481	97.235	91.2442
ENSG00000177885	homo_sapiens	ENSP00000339007	98.6175	95.3917	naja_naja	ENSNNAP00000029952	98.6175	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	98.6175	96.7742	podarcis_muralis	ENSPMRP00000023386	98.6175	96.7742
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	96.7742	geospiza_fortis	ENSGFOP00000012710	98.1567	96.7742
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	96.3134	taeniopygia_guttata	ENSTGUP00000008899	98.1567	96.3134
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	96.3134	erpetoichthys_calabaricus	ENSECRP00000031638	94.2478	92.4779
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	94.9309	kryptolebias_marmoratus	ENSKMAP00000017060	95.0893	91.9643
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	96.3134	salvator_merianae	ENSSMRP00000030250	99.0783	96.3134
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	oryzias_javanicus	ENSOJAP00000008059	97.6959	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	91.7051	amphilophus_citrinellus	ENSACIP00000028849	97.235	91.7051
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	95.3917	dicentrarchus_labrax	ENSDLAP00005063900	97.6959	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	amphiprion_percula	ENSAPEP00000020950	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	oryzias_sinensis	ENSOSIP00000033755	97.2477	93.578
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.235	pelodiscus_sinensis	ENSPSIP00000010170	99.0783	97.235
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.235	gopherus_evgoodei	ENSGEVP00005027190	78.7546	77.2894
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.235	chelonoidis_abingdonii	ENSCABP00000014352	99.0783	97.235
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	seriola_dumerili	ENSSDUP00000024464	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.3917	cottoperca_gobio	ENSCGOP00000023498	98.1567	95.3917
ENSG00000177885	homo_sapiens	ENSP00000339007	92.1659	88.4793	struthio_camelus_australis	ENSSCUP00000002665	83.682	80.3347
ENSG00000177885	homo_sapiens	ENSP00000339007	86.6359	83.871	anser_brachyrhynchus	ENSABRP00000019543	92.6108	89.6552
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.47	gasterosteus_aculeatus	ENSGACP00000009150	97.6959	94.47
ENSG00000177885	homo_sapiens	ENSP00000339007	95.8525	91.2442	cynoglossus_semilaevis	ENSCSEP00000022549	94.5455	90
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	poecilia_formosa	ENSPFOP00000005140	97.6959	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.9309	myripristis_murdjan	ENSMMDP00005011725	97.6959	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.9309	sander_lucioperca	ENSSLUP00000012740	97.6959	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.6959	strigops_habroptila	ENSSHBP00005016096	99.0783	97.6959
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	amphiprion_ocellaris	ENSAOCP00000031418	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	98.6175	96.7742	terrapene_carolina_triunguis	ENSTMTP00000021172	98.6175	96.7742
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	94.9309	hucho_hucho	ENSHHUP00000004240	97.235	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	94.9309	hucho_hucho	ENSHHUP00000075953	97.235	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	94.9309	betta_splendens	ENSBSLP00000017114	97.235	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	98.6175	94.0092	pygocentrus_nattereri	ENSPNAP00000001363	98.6175	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	anabas_testudineus	ENSATEP00000051436	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	57.6037	47.0046	ciona_savignyi	ENSCSAVP00000012036	44.3262	36.1702
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	seriola_lalandi_dorsalis	ENSSLDP00000031562	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	89.8617	86.6359	labrus_bergylta	ENSLBEP00000028315	88.2353	85.0679
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.3917	labrus_bergylta	ENSLBEP00000022583	92.6087	90
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	91.2442	pundamilia_nyererei	ENSPNYP00000028046	97.235	91.2442
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	mastacembelus_armatus	ENSMAMP00000049272	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	96.3134	stegastes_partitus	ENSSPAP00000005312	98.1567	96.3134
ENSG00000177885	homo_sapiens	ENSP00000339007	41.4747	37.3272	oncorhynchus_tshawytscha	ENSOTSP00005086198	65.2174	58.6957
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	95.8525	acanthochromis_polyacanthus	ENSAPOP00000021957	98.1567	95.8525
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.6959	aquila_chrysaetos_chrysaetos	ENSACCP00020002495	99.0783	97.6959
ENSG00000177885	homo_sapiens	ENSP00000339007	88.4793	83.871	nothobranchius_furzeri	ENSNFUP00015035424	95.0495	90.099
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	cyprinodon_variegatus	ENSCVAP00000009535	97.6959	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	98.6175	94.47	denticeps_clupeoides	ENSDCDP00000048978	98.6175	94.47
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.47	larimichthys_crocea	ENSLCRP00005043951	97.6959	94.47
ENSG00000177885	homo_sapiens	ENSP00000339007	96.3134	89.4009	takifugu_rubripes	ENSTRUP00000020659	95	88.1818
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	96.7742	ficedula_albicollis	ENSFALP00000023828	77.4545	76.3636
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.47	hippocampus_comes	ENSHCOP00000021807	97.6959	94.47
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	94.0092	cyprinus_carpio_carpio	ENSCCRP00000112450	98.1567	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	cyprinus_carpio_carpio	ENSCCRP00000023207	95.4955	91.8919
ENSG00000177885	homo_sapiens	ENSP00000339007	99.0783	97.6959	coturnix_japonica	ENSCJPP00005000027	99.0783	97.6959
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	poecilia_latipinna	ENSPLAP00000012052	97.6959	94.0092
ENSG00000177885	homo_sapiens	ENSP00000339007	78.8018	72.3502	sinocyclocheilus_grahami	ENSSGRP00000027557	67.0588	61.5686
ENSG00000177885	homo_sapiens	ENSP00000339007	97.235	91.2442	maylandia_zebra	ENSMZEP00005005680	97.235	91.2442
ENSG00000177885	homo_sapiens	ENSP00000339007	59.9078	53.4562	tetraodon_nigroviridis	ENSTNIP00000006587	84.9673	75.817
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.9309	paramormyrops_kingsleyae	ENSPKIP00000007863	97.6959	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.9309	scleropages_formosus	ENSSFOP00015070650	97.6959	94.9309
ENSG00000177885	homo_sapiens	ENSP00000339007	98.1567	94.0092	scophthalmus_maximus	ENSSMAP00000056687	97.2603	93.1507
ENSG00000177885	homo_sapiens	ENSP00000339007	97.6959	94.0092	oryzias_melastigma	ENSOMEP00000026652	97.6959	94.0092

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001784	enables phosphotyrosine residue binding	2	IBA,IPI	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005068	enables transmembrane receptor protein tyrosine kinase adaptor activity	1	IEA	Homo_sapiens(9606)	Function
GO:0005091	enables guanyl-nucleotide exchange factor adaptor activity	1	IEA	Homo_sapiens(9606)	Function
GO:0005154	enables epidermal growth factor receptor binding	2	IBA,IPI	Homo_sapiens(9606)	Function
GO:0005168	enables neurotrophin TRKA receptor binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005654	is_active_in nucleoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005768	located_in endosome	1	IDA	Homo_sapiens(9606)	Component
GO:0005794	located_in Golgi apparatus	1	IEA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0005886	is_active_in plasma membrane	2	IBA,TAS	Homo_sapiens(9606)	Component
GO:0005911	located_in cell-cell junction	1	IEA	Homo_sapiens(9606)	Component
GO:0007165	involved_in signal transduction	1	IBA	Homo_sapiens(9606)	Process
GO:0007173	involved_in epidermal growth factor receptor signaling pathway	2	IMP,TAS	Homo_sapiens(9606)	Process
GO:0007265	involved_in Ras protein signal transduction	1	TAS	Homo_sapiens(9606)	Process
GO:0008180	part_of COP9 signalosome	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0008286	involved_in insulin receptor signaling pathway	1	IPI	Homo_sapiens(9606)	Process
GO:0008543	involved_in fibroblast growth factor receptor signaling pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0012506	located_in vesicle membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0017124	enables SH3 domain binding	1	IDA	Homo_sapiens(9606)	Function
GO:0019901	enables protein kinase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0019903	enables protein phosphatase binding	1	IEA	Homo_sapiens(9606)	Function
GO:0030036	acts_upstream_of_or_within actin cytoskeleton organization	1	IMP	Homo_sapiens(9606)	Process
GO:0030838	involved_in positive regulation of actin filament polymerization	1	IEA	Homo_sapiens(9606)	Process
GO:0031623	involved_in receptor internalization	1	IMP	Homo_sapiens(9606)	Process
GO:0035987	involved_in endodermal cell differentiation	1	IEA	Homo_sapiens(9606)	Process
GO:0042770	involved_in signal transduction in response to DNA damage	1	IMP	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0043408	involved_in regulation of MAPK cascade	1	IBA	Homo_sapiens(9606)	Process
GO:0043560	enables insulin receptor substrate binding	1	IPI	Homo_sapiens(9606)	Function
GO:0046875	enables ephrin receptor binding	1	IPI	Homo_sapiens(9606)	Function
GO:0048009	involved_in insulin-like growth factor receptor signaling pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0050853	involved_in B cell receptor signaling pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0060670	involved_in branching involved in labyrinthine layer morphogenesis	1	IEA	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:0070436	part_of Grb2-EGFR complex	1	IDA	Homo_sapiens(9606)	Component
GO:0071479	involved_in cellular response to ionizing radiation	1	IMP	Homo_sapiens(9606)	Process
GO:2000379	involved_in positive regulation of reactive oxygen species metabolic process	1	IMP	Homo_sapiens(9606)	Process

Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression