RBP Type
Non-canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
Kinase
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000176444 Gene ID
1196 Accession
2069
Symbol
CLK2
Alias
NA
Full Name
CDC like kinase 2
Status
Confidence
Length
10637 bases
Strand
Minus strand
Position
1 : 155262868 - 155273504
RNA binding domain
N.A.
Summary
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
24069033 Phosphorylation-mediated regulation of alternative splicing in cancer.
Chiara Naro
2013-01-01
International journal of cell biology
35986377 Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency.
Subha Dahal
2022-08-19
Retrovirology
28232751 CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.
Tyler Funnell
2017-02-23
Nature communications
Name
Transcript ID
bp
Protein
Translation ID
CLK2-202
ENST00000361168
1934
498aa
ENSP00000354856
CLK2-203
ENST00000368361
2154
499aa
ENSP00000357345
CLK2-205
ENST00000476983
1885
No protein
-
CLK2-201
ENST00000355560
2120
497aa
ENSP00000347759
CLK2-207
ENST00000497188
2702
No protein
-
CLK2-204
ENST00000471047
701
No protein
-
CLK2-206
ENST00000484699
585
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
48131 Child Development Disorders, Pervasive 1.0935000E-005 - 48171 Child Development Disorders, Pervasive 9.4482000E-006 - 48753 Autistic Disorder 2.4454000E-005 - 48895 Child Development Disorders, Pervasive 2.1450000E-005 - 48939 Child Development Disorders, Pervasive 1.2618000E-005 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000176444 homo_sapiens ENSP00000291823 27.5974 16.3961 homo_sapiens ENSP00000357345 34.0681 20.2405 ENSG00000176444 homo_sapiens ENSP00000356076 36.3946 19.0476 homo_sapiens ENSP00000357345 42.8858 22.4449 ENSG00000176444 homo_sapiens ENSP00000378505 74.4898 61.4286 homo_sapiens ENSP00000357345 73.1463 60.3206 ENSG00000176444 homo_sapiens ENSP00000494572 25.4642 14.8541 homo_sapiens ENSP00000357345 38.477 22.4449 ENSG00000176444 homo_sapiens ENSP00000304226 17.7778 9.95885 homo_sapiens ENSP00000357345 43.2866 24.2485 ENSG00000176444 homo_sapiens ENSP00000326830 70.2479 54.3388 homo_sapiens ENSP00000357345 68.1363 52.7054 ENSG00000176444 homo_sapiens ENSP00000385571 17.9466 10.2671 homo_sapiens ENSP00000357345 43.0862 24.6493 ENSG00000176444 homo_sapiens ENSP00000407442 17.6033 9.75207 homo_sapiens ENSP00000357345 42.6854 23.6473 ENSG00000176444 homo_sapiens ENSP00000439697 32.3344 18.1388 homo_sapiens ENSP00000357345 41.0822 23.0461 ENSG00000176444 homo_sapiens ENSP00000316948 70.894 55.3015 homo_sapiens ENSP00000357345 68.3367 53.3066 ENSG00000176444 homo_sapiens ENSP00000342105 33.9434 18.3028 homo_sapiens ENSP00000357345 40.8818 22.0441 ENSG00000176444 homo_sapiens ENSP00000312789 30.3657 18.442 homo_sapiens ENSP00000357345 38.2766 23.2465 ENSG00000176444 homo_sapiens ENSP00000460443 100 100 homo_sapiens ENSP00000357345 100 100
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000176444 homo_sapiens ENSP00000357345 96.7936 96.1924 nomascus_leucogenys ENSNLEP00000047228 96.6 96 ENSG00000176444 homo_sapiens ENSP00000357345 100 100 pan_paniscus ENSPPAP00000042155 100 100 ENSG00000176444 homo_sapiens ENSP00000357345 100 100 pongo_abelii ENSPPYP00000000869 100 100 ENSG00000176444 homo_sapiens ENSP00000357345 100 100 pan_troglodytes ENSPTRP00000051728 100 100 ENSG00000176444 homo_sapiens ENSP00000357345 99.7996 99.5992 gorilla_gorilla ENSGGOP00000032058 98.2249 98.0276 ENSG00000176444 homo_sapiens ENSP00000357345 86.1723 81.1623 ornithorhynchus_anatinus ENSOANP00000048063 70.6076 66.5025 ENSG00000176444 homo_sapiens ENSP00000357345 97.5952 95.1904 sarcophilus_harrisii ENSSHAP00000009635 97.9879 95.5734 ENSG00000176444 homo_sapiens ENSP00000357345 56.7134 55.7114 notamacropus_eugenii ENSMEUP00000014376 87.8882 86.3354 ENSG00000176444 homo_sapiens ENSP00000357345 65.5311 65.1303 choloepus_hoffmanni ENSCHOP00000010368 89.3443 88.7978 ENSG00000176444 homo_sapiens ENSP00000357345 68.5371 67.7355 dasypus_novemcinctus ENSDNOP00000024809 93.4426 92.3497 ENSG00000176444 homo_sapiens ENSP00000357345 66.5331 65.5311 erinaceus_europaeus ENSEEUP00000001436 66.4 65.4 ENSG00000176444 homo_sapiens ENSP00000357345 98.1964 96.994 echinops_telfairi ENSETEP00000000920 98 96.8 ENSG00000176444 homo_sapiens ENSP00000357345 99.5992 99.3988 callithrix_jacchus ENSCJAP00000015609 99.5992 99.3988 ENSG00000176444 homo_sapiens ENSP00000357345 99.7996 99.7996 cercocebus_atys ENSCATP00000016822 98.2249 98.2249 ENSG00000176444 homo_sapiens ENSP00000357345 99.5992 99.5992 macaca_fascicularis ENSMFAP00000019215 99.5992 99.5992 ENSG00000176444 homo_sapiens ENSP00000357345 91.984 90.982 macaca_mulatta ENSMMUP00000074240 84.2202 83.3027 ENSG00000176444 homo_sapiens ENSP00000357345 99.7996 99.5992 macaca_nemestrina ENSMNEP00000013894 98.2249 98.0276 ENSG00000176444 homo_sapiens ENSP00000357345 99.7996 99.7996 papio_anubis ENSPANP00000000322 99.7996 99.7996 ENSG00000176444 homo_sapiens ENSP00000357345 99.7996 99.5992 mandrillus_leucophaeus ENSMLEP00000000776 98.2249 98.0276 ENSG00000176444 homo_sapiens ENSP00000357345 58.517 58.517 tursiops_truncatus ENSTTRP00000008972 58.517 58.517 ENSG00000176444 homo_sapiens ENSP00000357345 92.7856 90.5812 vulpes_vulpes ENSVVUP00000004949 60.6021 59.1623 ENSG00000176444 homo_sapiens ENSP00000357345 98.7976 97.5952 mus_spretus MGP_SPRETEiJ_P0060908 98.6 97.4 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 98.998 equus_asinus ENSEASP00005028347 76.7802 76.4706 ENSG00000176444 homo_sapiens ENSP00000357345 97.5952 97.1944 capra_hircus ENSCHIP00000030379 99.1853 98.778 ENSG00000176444 homo_sapiens ENSP00000357345 95.5912 95.1904 loxodonta_africana ENSLAFP00000025478 95.4 95 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 98.7976 panthera_leo ENSPLOP00000012456 99.2 98.6 ENSG00000176444 homo_sapiens ENSP00000357345 78.5571 75.3507 ailuropoda_melanoleuca ENSAMEP00000000075 81.3278 78.0083 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 99.1984 bos_indicus_hybrid ENSBIXP00005006149 99.2 99 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 98.7976 oryctolagus_cuniculus ENSOCUP00000000318 99.2 98.6 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 98.998 equus_caballus ENSECAP00000019168 76.7802 76.4706 ENSG00000176444 homo_sapiens ENSP00000357345 98.5972 98.3968 canis_lupus_familiaris ENSCAFP00845017205 98.4 98.2 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.5972 panthera_pardus ENSPPRP00000002324 99 98.4 ENSG00000176444 homo_sapiens ENSP00000357345 92.7856 92.3848 marmota_marmota_marmota ENSMMMP00000016312 98.9316 98.5043 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.998 balaenoptera_musculus ENSBMSP00010004170 99 98.8 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 99.1984 cavia_porcellus ENSCPOP00000032975 99.2 99 ENSG00000176444 homo_sapiens ENSP00000357345 92.3848 89.5792 felis_catus ENSFCAP00000054074 81.5929 79.115 ENSG00000176444 homo_sapiens ENSP00000357345 98.5972 97.7956 ursus_americanus ENSUAMP00000026507 98.4 97.6 ENSG00000176444 homo_sapiens ENSP00000357345 47.0942 44.8898 monodelphis_domestica ENSMODP00000033852 87.3606 83.2714 ENSG00000176444 homo_sapiens ENSP00000357345 25.8517 24.2485 monodelphis_domestica ENSMODP00000055672 85.4305 80.1325 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 99.1984 bison_bison_bison ENSBBBP00000006551 99.2 99 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.998 monodon_monoceros ENSMMNP00015017218 99 98.8 ENSG00000176444 homo_sapiens ENSP00000357345 98.7976 98.1964 sus_scrofa ENSSSCP00000043830 93.1947 92.6276 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.5972 microcebus_murinus ENSMICP00000027830 99 98.4 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.998 octodon_degus ENSODEP00000013111 99 98.8 ENSG00000176444 homo_sapiens ENSP00000357345 96.994 94.99 jaculus_jaculus ENSJJAP00000020073 96.6068 94.6108 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 99.1984 ovis_aries_rambouillet ENSOARP00020014691 99.2 99 ENSG00000176444 homo_sapiens ENSP00000357345 93.7876 92.986 ursus_maritimus ENSUMAP00000026782 98.1132 97.2746 ENSG00000176444 homo_sapiens ENSP00000357345 85.5711 84.1683 ochotona_princeps ENSOPRP00000000149 97.7117 96.1098 ENSG00000176444 homo_sapiens ENSP00000357345 93.5872 91.5832 delphinapterus_leucas ENSDLEP00000021769 58.5213 57.2682 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 99.1984 physeter_catodon ENSPCTP00005028053 98.6084 98.4095 ENSG00000176444 homo_sapiens ENSP00000357345 98.998 97.7956 mus_caroli MGP_CAROLIEiJ_P0058561 98.8 97.6 ENSG00000176444 homo_sapiens ENSP00000357345 98.5972 96.994 mus_musculus ENSMUSP00000113861 98.4 96.8 ENSG00000176444 homo_sapiens ENSP00000357345 98.1964 97.7956 dipodomys_ordii ENSDORP00000010926 98 97.6 ENSG00000176444 homo_sapiens ENSP00000357345 92.3848 89.3788 mustela_putorius_furo ENSMPUP00000005502 60.4194 58.4535 ENSG00000176444 homo_sapiens ENSP00000357345 91.7836 89.7796 aotus_nancymaae ENSANAP00000005689 60.184 58.8699 ENSG00000176444 homo_sapiens ENSP00000357345 100 100 saimiri_boliviensis_boliviensis ENSSBOP00000021369 100 100 ENSG00000176444 homo_sapiens ENSP00000357345 88.5772 88.3768 chlorocebus_sabaeus ENSCSAP00000016016 98.6607 98.4375 ENSG00000176444 homo_sapiens ENSP00000357345 91.984 91.7836 tupaia_belangeri ENSTBEP00000000186 92.5403 92.3387 ENSG00000176444 homo_sapiens ENSP00000357345 98.5972 97.5952 mesocricetus_auratus ENSMAUP00000018136 98.4 97.4 ENSG00000176444 homo_sapiens ENSP00000357345 92.5852 92.1844 phocoena_sinus ENSPSNP00000000630 97.6744 97.2516 ENSG00000176444 homo_sapiens ENSP00000357345 98.5972 97.996 camelus_dromedarius ENSCDRP00005011268 98.7952 98.1928 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.5972 carlito_syrichta ENSTSYP00000008781 99 98.4 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.3968 panthera_tigris_altaica ENSPTIP00000009957 99.1984 98.3968 ENSG00000176444 homo_sapiens ENSP00000357345 93.1864 89.98 rattus_norvegicus ENSRNOP00000027793 58.1977 56.1952 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.7976 prolemur_simus ENSPSMP00000034448 99 98.6 ENSG00000176444 homo_sapiens ENSP00000357345 97.996 96.994 microtus_ochrogaster ENSMOCP00000014785 97.8 96.8 ENSG00000176444 homo_sapiens ENSP00000357345 88.3768 87.5751 sorex_araneus ENSSARP00000012735 88.7324 87.9276 ENSG00000176444 homo_sapiens ENSP00000357345 98.7976 98.1964 peromyscus_maniculatus_bairdii ENSPEMP00000011664 98.6 98 ENSG00000176444 homo_sapiens ENSP00000357345 96.5932 96.5932 bos_mutus ENSBMUP00000017164 96.4 96.4 ENSG00000176444 homo_sapiens ENSP00000357345 98.3968 96.994 mus_spicilegus ENSMSIP00000030834 98.5944 97.1888 ENSG00000176444 homo_sapiens ENSP00000357345 97.7956 97.3948 cricetulus_griseus_chok1gshd ENSCGRP00001012999 97.6 97.2 ENSG00000176444 homo_sapiens ENSP00000357345 98.7976 97.3948 pteropus_vampyrus ENSPVAP00000005485 98.6 97.2 ENSG00000176444 homo_sapiens ENSP00000357345 98.1964 97.7956 myotis_lucifugus ENSMLUP00000012203 98.1964 97.7956 ENSG00000176444 homo_sapiens ENSP00000357345 97.3948 95.1904 vombatus_ursinus ENSVURP00010019903 97.7867 95.5734 ENSG00000176444 homo_sapiens ENSP00000357345 97.3948 95.1904 vombatus_ursinus ENSVURP00010018988 97.7867 95.5734 ENSG00000176444 homo_sapiens ENSP00000357345 97.3948 95.1904 vombatus_ursinus ENSVURP00010018944 97.7867 95.5734 ENSG00000176444 homo_sapiens ENSP00000357345 98.3968 97.5952 rhinolophus_ferrumequinum ENSRFEP00010018710 98.2 97.4 ENSG00000176444 homo_sapiens ENSP00000357345 97.3948 96.1924 neovison_vison ENSNVIP00000025146 95.858 94.6746 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 99.1984 bos_taurus ENSBTAP00000019139 99.2 99 ENSG00000176444 homo_sapiens ENSP00000357345 99.5992 99.5992 rhinopithecus_bieti ENSRBIP00000023382 99.5992 99.5992 ENSG00000176444 homo_sapiens ENSP00000357345 98.3968 98.1964 canis_lupus_dingo ENSCAFP00020008760 98.3968 98.1964 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 98.998 sciurus_vulgaris ENSSVLP00005025331 99.2 98.8 ENSG00000176444 homo_sapiens ENSP00000357345 97.5952 95.3908 phascolarctos_cinereus ENSPCIP00000029142 94.1973 92.0696 ENSG00000176444 homo_sapiens ENSP00000357345 44.6894 44.2886 procavia_capensis ENSPCAP00000013326 50.3386 49.8871 ENSG00000176444 homo_sapiens ENSP00000357345 98.3968 97.7956 nannospalax_galili ENSNGAP00000024188 98.3968 97.7956 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 99.1984 bos_grunniens ENSBGRP00000031458 99.2 99 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 99.1984 chinchilla_lanigera ENSCLAP00000005459 99.2 99 ENSG00000176444 homo_sapiens ENSP00000357345 99.3988 98.998 cervus_hanglu_yarkandensis ENSCHYP00000007807 99.2 98.8 ENSG00000176444 homo_sapiens ENSP00000357345 98.7976 98.1964 catagonus_wagneri ENSCWAP00000027193 98.6 98 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.7976 ictidomys_tridecemlineatus ENSSTOP00000008038 99 98.6 ENSG00000176444 homo_sapiens ENSP00000357345 98.5972 97.996 otolemur_garnettii ENSOGAP00000008579 98.4 97.8 ENSG00000176444 homo_sapiens ENSP00000357345 100 100 cebus_imitator ENSCCAP00000040127 92.5788 92.5788 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.7976 urocitellus_parryii ENSUPAP00010003281 99 98.6 ENSG00000176444 homo_sapiens ENSP00000357345 98.998 98.7976 moschus_moschiferus ENSMMSP00000009867 98.8 98.6 ENSG00000176444 homo_sapiens ENSP00000357345 97.3948 97.1944 rhinopithecus_roxellana ENSRROP00000022399 97.7867 97.5855 ENSG00000176444 homo_sapiens ENSP00000357345 98.1964 96.7936 mus_pahari MGP_PahariEiJ_P0069520 98.5916 97.1831 ENSG00000176444 homo_sapiens ENSP00000357345 99.1984 98.7976 propithecus_coquereli ENSPCOP00000029521 99 98.6 ENSG00000176444 homo_sapiens ENSP00000357345 67.3347 50.9018 caenorhabditis_elegans E02H4.3e.1 37.7528 28.5393 ENSG00000176444 homo_sapiens ENSP00000357345 75.5511 61.3226 drosophila_melanogaster FBpp0289029 18.4352 14.9633 ENSG00000176444 homo_sapiens ENSP00000357345 70.5411 57.515 ciona_intestinalis ENSCINP00000016222 70.825 57.7465 ENSG00000176444 homo_sapiens ENSP00000357345 83.9679 69.7395 petromyzon_marinus ENSPMAP00000002526 82.8063 68.7747 ENSG00000176444 homo_sapiens ENSP00000357345 70.9419 55.511 eptatretus_burgeri ENSEBUP00000009963 66.2921 51.8727 ENSG00000176444 homo_sapiens ENSP00000357345 53.507 46.8938 callorhinchus_milii ENSCMIP00000009077 87.8289 76.9737 ENSG00000176444 homo_sapiens ENSP00000357345 93.1864 85.5711 latimeria_chalumnae ENSLACP00000014589 92.0792 84.5545 ENSG00000176444 homo_sapiens ENSP00000357345 67.1343 61.523 lepisosteus_oculatus ENSLOCP00000007969 89.3333 81.8667 ENSG00000176444 homo_sapiens ENSP00000357345 86.9739 76.3527 clupea_harengus ENSCHAP00000034784 82.197 72.1591 ENSG00000176444 homo_sapiens ENSP00000357345 67.7355 54.509 clupea_harengus ENSCHAP00000010138 83.2512 66.9951 ENSG00000176444 homo_sapiens ENSP00000357345 87.5751 78.1563 danio_rerio ENSDARP00000112318 83.0798 74.1445 ENSG00000176444 homo_sapiens ENSP00000357345 79.3587 68.9379 danio_rerio ENSDARP00000078148 79.5181 69.0763 ENSG00000176444 homo_sapiens ENSP00000357345 64.9299 56.7134 carassius_auratus ENSCARP00000126839 79.6069 69.5332 ENSG00000176444 homo_sapiens ENSP00000357345 86.9739 77.1543 carassius_auratus ENSCARP00000037035 79.3419 70.3839 ENSG00000176444 homo_sapiens ENSP00000357345 86.9739 77.3547 carassius_auratus ENSCARP00000053079 82.3529 73.2448 ENSG00000176444 homo_sapiens ENSP00000357345 73.7475 63.5271 carassius_auratus ENSCARP00000005067 80.5252 69.3654 ENSG00000176444 homo_sapiens ENSP00000357345 57.9158 53.3066 astyanax_mexicanus ENSAMXP00000011552 91.746 84.4444 ENSG00000176444 homo_sapiens ENSP00000357345 87.1743 77.7555 astyanax_mexicanus ENSAMXP00000035661 83.3333 74.3295 ENSG00000176444 homo_sapiens ENSP00000357345 86.1723 75.5511 ictalurus_punctatus ENSIPUP00000011603 78.4672 68.7956 ENSG00000176444 homo_sapiens ENSP00000357345 45.491 38.477 ictalurus_punctatus ENSIPUP00000000022 79.6491 67.3684 ENSG00000176444 homo_sapiens ENSP00000357345 86.7735 77.1543 esox_lucius ENSELUP00000059056 81.6981 72.6415 ENSG00000176444 homo_sapiens ENSP00000357345 43.487 36.8737 electrophorus_electricus ENSEEEP00000010509 82.5095 69.962 ENSG00000176444 homo_sapiens ENSP00000357345 83.9679 74.9499 electrophorus_electricus ENSEEEP00000015353 85.3361 76.1711 ENSG00000176444 homo_sapiens ENSP00000357345 57.3146 48.0962 oncorhynchus_kisutch ENSOKIP00005004640 78.3562 65.7534 ENSG00000176444 homo_sapiens ENSP00000357345 84.9699 76.7535 oncorhynchus_kisutch ENSOKIP00005063229 84.2942 76.1431 ENSG00000176444 homo_sapiens ENSP00000357345 62.3246 53.3066 oncorhynchus_kisutch ENSOKIP00005081443 80.3618 68.7338 ENSG00000176444 homo_sapiens ENSP00000357345 85.9719 76.9539 oncorhynchus_kisutch ENSOKIP00005011537 81.7143 73.1429 ENSG00000176444 homo_sapiens ENSP00000357345 62.3246 53.7074 oncorhynchus_mykiss ENSOMYP00000113425 80.3618 69.2506 ENSG00000176444 homo_sapiens ENSP00000357345 76.5531 68.7375 oncorhynchus_mykiss ENSOMYP00000093930 63.4552 56.9767 ENSG00000176444 homo_sapiens ENSP00000357345 85.9719 76.9539 oncorhynchus_mykiss ENSOMYP00000009655 81.4042 72.8653 ENSG00000176444 homo_sapiens ENSP00000357345 85.5711 76.5531 salmo_salar ENSSSAP00000179865 80.4143 71.9397 ENSG00000176444 homo_sapiens ENSP00000357345 62.7255 53.7074 salmo_salar ENSSSAP00000136817 80.0511 68.5422 ENSG00000176444 homo_sapiens ENSP00000357345 62.5251 53.1062 salmo_salar ENSSSAP00000036974 80.829 68.6528 ENSG00000176444 homo_sapiens ENSP00000357345 86.7735 77.9559 salmo_salar ENSSSAP00000066584 77.4597 69.5886 ENSG00000176444 homo_sapiens ENSP00000357345 86.7735 77.9559 salmo_trutta ENSSTUP00000088412 81.391 73.1203 ENSG00000176444 homo_sapiens ENSP00000357345 85.5711 76.3527 salmo_trutta ENSSTUP00000078830 80.566 71.8868 ENSG00000176444 homo_sapiens ENSP00000357345 62.3246 53.507 salmo_trutta ENSSTUP00000085127 80.3618 68.9922 ENSG00000176444 homo_sapiens ENSP00000357345 73.3467 65.7315 gadus_morhua ENSGMOP00000036188 71.9057 64.4401 ENSG00000176444 homo_sapiens ENSP00000357345 59.9198 50.501 gadus_morhua ENSGMOP00000025467 72.3971 61.0169 ENSG00000176444 homo_sapiens ENSP00000357345 86.5731 75.9519 fundulus_heteroclitus ENSFHEP00000028440 82.4427 72.3282 ENSG00000176444 homo_sapiens ENSP00000357345 46.6934 39.6794 fundulus_heteroclitus ENSFHEP00000020298 79.2517 67.3469 ENSG00000176444 homo_sapiens ENSP00000357345 44.489 38.0762 poecilia_reticulata ENSPREP00000025903 81.9188 70.1107 ENSG00000176444 homo_sapiens ENSP00000357345 87.3747 76.3527 poecilia_reticulata ENSPREP00000027822 83.0476 72.5714 ENSG00000176444 homo_sapiens ENSP00000357345 87.3747 76.5531 xiphophorus_maculatus ENSXMAP00000014603 83.0476 72.7619 ENSG00000176444 homo_sapiens ENSP00000357345 50.9018 43.6874 xiphophorus_maculatus ENSXMAP00000016700 79.8742 68.5535 ENSG00000176444 homo_sapiens ENSP00000357345 87.3747 74.9499 oryzias_latipes ENSORLP00000003191 83.3652 71.5105 ENSG00000176444 homo_sapiens ENSP00000357345 59.519 48.6974 oryzias_latipes ENSORLP00000013308 78.1579 63.9474 ENSG00000176444 homo_sapiens ENSP00000357345 87.976 77.1543 cyclopterus_lumpus ENSCLMP00005033204 82.364 72.2326 ENSG00000176444 homo_sapiens ENSP00000357345 51.1022 43.2866 cyclopterus_lumpus ENSCLMP00005020375 84.1584 71.2871 ENSG00000176444 homo_sapiens ENSP00000357345 88.1764 77.9559 oreochromis_niloticus ENSONIP00000073056 72.9685 64.5108 ENSG00000176444 homo_sapiens ENSP00000357345 60.9218 52.3046 oreochromis_niloticus ENSONIP00000032547 69.5652 59.7254 ENSG00000176444 homo_sapiens ENSP00000357345 87.976 77.3547 haplochromis_burtoni ENSHBUP00000033269 82.9868 72.9679 ENSG00000176444 homo_sapiens ENSP00000357345 52.3046 44.8898 haplochromis_burtoni ENSHBUP00000023683 83.9228 72.0257 ENSG00000176444 homo_sapiens ENSP00000357345 87.976 77.3547 astatotilapia_calliptera ENSACLP00000014015 83.619 73.5238 ENSG00000176444 homo_sapiens ENSP00000357345 43.6874 38.2766 astatotilapia_calliptera ENSACLP00000030345 82.8897 72.6236 ENSG00000176444 homo_sapiens ENSP00000357345 87.5751 76.9539 sparus_aurata ENSSAUP00010012443 82.6087 72.5898 ENSG00000176444 homo_sapiens ENSP00000357345 59.1182 48.0962 sparus_aurata ENSSAUP00010042645 81.4917 66.2983 ENSG00000176444 homo_sapiens ENSP00000357345 70.7415 64.1283 lates_calcarifer ENSLCAP00010058180 84.4498 76.555 ENSG00000176444 homo_sapiens ENSP00000357345 62.9258 53.1062 lates_calcarifer ENSLCAP00010052803 80.7198 68.1234 ENSG00000176444 homo_sapiens ENSP00000357345 71.5431 65.3307 lates_calcarifer ENSLCAP00010047820 85.6115 78.1775 ENSG00000176444 homo_sapiens ENSP00000357345 90.982 83.3667 xenopus_tropicalis ENSXETP00000038336 90.2584 82.7038 ENSG00000176444 homo_sapiens ENSP00000357345 94.7896 89.7796 chrysemys_picta_bellii ENSCPBP00000037061 93.6634 88.7129 ENSG00000176444 homo_sapiens ENSP00000357345 64.7295 62.3246 sphenodon_punctatus ENSSPUP00000020896 88.4931 85.2055 ENSG00000176444 homo_sapiens ENSP00000357345 89.98 84.9699 crocodylus_porosus ENSCPRP00005004719 58.5398 55.2803 ENSG00000176444 homo_sapiens ENSP00000357345 89.7796 81.9639 laticauda_laticaudata ENSLLTP00000012267 80.4309 73.4291 ENSG00000176444 homo_sapiens ENSP00000357345 32.0641 28.6573 notechis_scutatus ENSNSUP00000021832 78.8177 70.4434 ENSG00000176444 homo_sapiens ENSP00000357345 89.98 82.7655 pseudonaja_textilis ENSPTXP00000024601 89.4422 82.2709 ENSG00000176444 homo_sapiens ENSP00000357345 27.8557 25.4509 pseudonaja_textilis ENSPTXP00000019663 77.2222 70.5556 ENSG00000176444 homo_sapiens ENSP00000357345 27.8557 25.4509 pseudonaja_textilis ENSPTXP00000019666 77.2222 70.5556 ENSG00000176444 homo_sapiens ENSP00000357345 94.3888 89.3788 anas_platyrhynchos_platyrhynchos ENSAPLP00000011999 82.3427 77.972 ENSG00000176444 homo_sapiens ENSP00000357345 93.5872 88.5772 gallus_gallus ENSGALP00010041522 93.2136 88.2236 ENSG00000176444 homo_sapiens ENSP00000357345 93.7876 88.5772 meleagris_gallopavo ENSMGAP00000018282 82.5397 77.9541 ENSG00000176444 homo_sapiens ENSP00000357345 76.3527 71.1423 serinus_canaria ENSSCAP00000016776 55.5394 51.7493 ENSG00000176444 homo_sapiens ENSP00000357345 70.9419 65.1303 parus_major ENSPMJP00000012759 58.804 53.9867 ENSG00000176444 homo_sapiens ENSP00000357345 91.3828 86.1723 anolis_carolinensis ENSACAP00000002580 91.9355 86.6936 ENSG00000176444 homo_sapiens ENSP00000357345 45.0902 39.2786 neolamprologus_brichardi ENSNBRP00000003894 83.0258 72.3247 ENSG00000176444 homo_sapiens ENSP00000357345 84.7695 73.7475 neolamprologus_brichardi ENSNBRP00000023229 78.3333 68.1481 ENSG00000176444 homo_sapiens ENSP00000357345 91.984 86.7735 podarcis_muralis ENSPMRP00000026010 81.2389 76.6372 ENSG00000176444 homo_sapiens ENSP00000357345 65.9319 62.7255 geospiza_fortis ENSGFOP00000014238 95.9184 91.2536 ENSG00000176444 homo_sapiens ENSP00000357345 94.1884 89.1784 taeniopygia_guttata ENSTGUP00000016909 93.254 88.2936 ENSG00000176444 homo_sapiens ENSP00000357345 46.493 40.0802 kryptolebias_marmoratus ENSKMAP00000001487 80 68.9655 ENSG00000176444 homo_sapiens ENSP00000357345 87.976 77.3547 kryptolebias_marmoratus ENSKMAP00000016189 83.619 73.5238 ENSG00000176444 homo_sapiens ENSP00000357345 90.5812 84.1683 salvator_merianae ENSSMRP00000014655 90.5812 84.1683 ENSG00000176444 homo_sapiens ENSP00000357345 86.3727 74.5491 oryzias_javanicus ENSOJAP00000009298 83.8521 72.3735 ENSG00000176444 homo_sapiens ENSP00000357345 51.1022 43.6874 amphilophus_citrinellus ENSACIP00000009353 83.6066 71.4754 ENSG00000176444 homo_sapiens ENSP00000357345 74.7495 66.9339 amphilophus_citrinellus ENSACIP00000013866 84.3891 75.5656 ENSG00000176444 homo_sapiens ENSP00000357345 61.523 51.9038 dicentrarchus_labrax ENSDLAP00005013492 76.75 64.75 ENSG00000176444 homo_sapiens ENSP00000357345 88.1764 77.5551 dicentrarchus_labrax ENSDLAP00005006717 82.8625 72.8814 ENSG00000176444 homo_sapiens ENSP00000357345 88.1764 77.7555 amphiprion_percula ENSAPEP00000012119 83.0189 73.2076 ENSG00000176444 homo_sapiens ENSP00000357345 51.9038 45.0902 amphiprion_percula ENSAPEP00000010243 77.0833 66.9643 ENSG00000176444 homo_sapiens ENSP00000357345 87.3747 75.1503 oryzias_sinensis ENSOSIP00000011386 82.8897 71.2928 ENSG00000176444 homo_sapiens ENSP00000357345 93.1864 89.5792 pelodiscus_sinensis ENSPSIP00000012159 92.0792 88.5149 ENSG00000176444 homo_sapiens ENSP00000357345 72.1443 66.5331 gopherus_evgoodei ENSGEVP00005012060 83.9161 77.3893 ENSG00000176444 homo_sapiens ENSP00000357345 93.988 88.5772 gopherus_evgoodei ENSGEVP00005009304 93.0556 87.6984 ENSG00000176444 homo_sapiens ENSP00000357345 94.7896 89.98 chelonoidis_abingdonii ENSCABP00000024261 93.8492 89.0873 ENSG00000176444 homo_sapiens ENSP00000357345 67.3347 55.511 seriola_dumerili ENSSDUP00000010309 34.9272 28.7942 ENSG00000176444 homo_sapiens ENSP00000357345 83.7675 74.5491 seriola_dumerili ENSSDUP00000025875 83.1014 73.9563 ENSG00000176444 homo_sapiens ENSP00000357345 86.7735 75.9519 cottoperca_gobio ENSCGOP00000028349 81.5443 71.3748 ENSG00000176444 homo_sapiens ENSP00000357345 60.7214 51.1022 cottoperca_gobio ENSCGOP00000005226 77.892 65.5527 ENSG00000176444 homo_sapiens ENSP00000357345 94.3888 89.7796 struthio_camelus_australis ENSSCUP00000004963 86.9004 82.6568 ENSG00000176444 homo_sapiens ENSP00000357345 94.3888 89.3788 anser_brachyrhynchus ENSABRP00000024247 93.4524 88.4921 ENSG00000176444 homo_sapiens ENSP00000357345 87.1743 76.3527 gasterosteus_aculeatus ENSGACP00000004232 82.5427 72.296 ENSG00000176444 homo_sapiens ENSP00000357345 42.6854 37.2745 gasterosteus_aculeatus ENSGACP00000015427 82.8794 72.3735 ENSG00000176444 homo_sapiens ENSP00000357345 78.5571 66.5331 cynoglossus_semilaevis ENSCSEP00000012365 73.271 62.0561 ENSG00000176444 homo_sapiens ENSP00000357345 64.1283 51.7034 cynoglossus_semilaevis ENSCSEP00000004752 70.4846 56.8282 ENSG00000176444 homo_sapiens ENSP00000357345 60.521 50.7014 poecilia_formosa ENSPFOP00000005432 77.635 65.0386 ENSG00000176444 homo_sapiens ENSP00000357345 87.1743 76.5531 poecilia_formosa ENSPFOP00000008081 82.6996 72.6236 ENSG00000176444 homo_sapiens ENSP00000357345 70.9419 63.7275 myripristis_murdjan ENSMMDP00005041073 83.8863 75.3555 ENSG00000176444 homo_sapiens ENSP00000357345 52.1042 45.6914 myripristis_murdjan ENSMMDP00005013666 83.6013 73.3119 ENSG00000176444 homo_sapiens ENSP00000357345 63.3267 52.1042 sander_lucioperca ENSSLUP00000027128 75.9615 62.5 ENSG00000176444 homo_sapiens ENSP00000357345 68.7375 61.523 sander_lucioperca ENSSLUP00000027525 82.0574 73.445 ENSG00000176444 homo_sapiens ENSP00000357345 93.7876 89.1784 strigops_habroptila ENSSHBP00005019334 92.8571 88.2936 ENSG00000176444 homo_sapiens ENSP00000357345 88.1764 77.7555 amphiprion_ocellaris ENSAOCP00000029883 83.0189 73.2076 ENSG00000176444 homo_sapiens ENSP00000357345 51.1022 44.8898 amphiprion_ocellaris ENSAOCP00000029436 80.9524 71.1111 ENSG00000176444 homo_sapiens ENSP00000357345 94.7896 89.5792 terrapene_carolina_triunguis ENSTMTP00000024330 93.6634 88.5149 ENSG00000176444 homo_sapiens ENSP00000357345 62.7255 54.1082 hucho_hucho ENSHHUP00000001109 79.4416 68.5279 ENSG00000176444 homo_sapiens ENSP00000357345 68.5371 62.1242 hucho_hucho ENSHHUP00000056419 83.2117 75.4258 ENSG00000176444 homo_sapiens ENSP00000357345 45.491 37.8758 hucho_hucho ENSHHUP00000007442 77.7397 64.726 ENSG00000176444 homo_sapiens ENSP00000357345 71.5431 65.3307 hucho_hucho ENSHHUP00000000432 87.0732 79.5122 ENSG00000176444 homo_sapiens ENSP00000357345 56.9138 47.2946 betta_splendens ENSBSLP00000046959 80.226 66.6667 ENSG00000176444 homo_sapiens ENSP00000357345 87.1743 75.5511 betta_splendens ENSBSLP00000034045 81.0056 70.2048 ENSG00000176444 homo_sapiens ENSP00000357345 82.1643 72.7455 pygocentrus_nattereri ENSPNAP00000015570 77.7989 68.8805 ENSG00000176444 homo_sapiens ENSP00000357345 86.5731 77.7555 pygocentrus_nattereri ENSPNAP00000011138 81.9734 73.6243 ENSG00000176444 homo_sapiens ENSP00000357345 70.7415 63.1263 anabas_testudineus ENSATEP00000056174 84.2482 75.179 ENSG00000176444 homo_sapiens ENSP00000357345 44.8898 38.477 anabas_testudineus ENSATEP00000034203 82.6568 70.8487 ENSG00000176444 homo_sapiens ENSP00000357345 71.5431 58.1162 ciona_savignyi ENSCSAVP00000006169 70.2756 57.0866 ENSG00000176444 homo_sapiens ENSP00000357345 53.7074 45.6914 seriola_lalandi_dorsalis ENSSLDP00000019345 83.75 71.25 ENSG00000176444 homo_sapiens ENSP00000357345 86.5731 76.7535 seriola_lalandi_dorsalis ENSSLDP00000017566 82.9175 73.5125 ENSG00000176444 homo_sapiens ENSP00000357345 45.0902 36.6733 labrus_bergylta ENSLBEP00000034281 74.5033 60.596 ENSG00000176444 homo_sapiens ENSP00000357345 87.5751 76.7535 labrus_bergylta ENSLBEP00000036028 81.9887 71.8574 ENSG00000176444 homo_sapiens ENSP00000357345 87.5751 76.9539 pundamilia_nyererei ENSPNYP00000015854 82.9222 72.8653 ENSG00000176444 homo_sapiens ENSP00000357345 45.2906 39.479 pundamilia_nyererei ENSPNYP00000005105 83.3948 72.6937 ENSG00000176444 homo_sapiens ENSP00000357345 61.3226 51.9038 mastacembelus_armatus ENSMAMP00000053328 78.6632 66.581 ENSG00000176444 homo_sapiens ENSP00000357345 70.1403 63.1263 mastacembelus_armatus ENSMAMP00000041612 84.5411 76.087 ENSG00000176444 homo_sapiens ENSP00000357345 51.9038 44.8898 stegastes_partitus ENSSPAP00000016268 81.962 70.8861 ENSG00000176444 homo_sapiens ENSP00000357345 88.1764 77.7555 stegastes_partitus ENSSPAP00000004774 82.7068 72.9323 ENSG00000176444 homo_sapiens ENSP00000357345 86.7735 77.7555 oncorhynchus_tshawytscha ENSOTSP00005024242 81.391 72.9323 ENSG00000176444 homo_sapiens ENSP00000357345 85.9719 76.7535 oncorhynchus_tshawytscha ENSOTSP00005100224 83.301 74.3689 ENSG00000176444 homo_sapiens ENSP00000357345 36.6733 30.2605 acanthochromis_polyacanthus ENSAPOP00000013467 69.0566 56.9811 ENSG00000176444 homo_sapiens ENSP00000357345 87.976 77.5551 acanthochromis_polyacanthus ENSAPOP00000004519 82.8302 73.0189 ENSG00000176444 homo_sapiens ENSP00000357345 93.5872 88.7776 aquila_chrysaetos_chrysaetos ENSACCP00020013392 92.8429 88.0716 ENSG00000176444 homo_sapiens ENSP00000357345 72.1443 65.3307 nothobranchius_furzeri ENSNFUP00015040351 87.5912 79.3187 ENSG00000176444 homo_sapiens ENSP00000357345 87.7756 76.1523 cyprinodon_variegatus ENSCVAP00000015362 83.4286 72.381 ENSG00000176444 homo_sapiens ENSP00000357345 51.9038 45.0902 cyprinodon_variegatus ENSCVAP00000007175 81.4465 70.7547 ENSG00000176444 homo_sapiens ENSP00000357345 62.5251 52.9058 denticeps_clupeoides ENSDCDP00000006807 70.7483 59.8639 ENSG00000176444 homo_sapiens ENSP00000357345 78.7575 69.9399 denticeps_clupeoides ENSDCDP00000039653 70.6835 62.7698 ENSG00000176444 homo_sapiens ENSP00000357345 85.1703 74.3487 larimichthys_crocea ENSLCRP00005049664 75.8929 66.25 ENSG00000176444 homo_sapiens ENSP00000357345 61.523 53.1062 larimichthys_crocea ENSLCRP00005006124 77.33 66.7506 ENSG00000176444 homo_sapiens ENSP00000357345 72.5451 65.5311 takifugu_rubripes ENSTRUP00000022993 88.0779 79.562 ENSG00000176444 homo_sapiens ENSP00000357345 74.9499 68.7375 ficedula_albicollis ENSFALP00000033611 72.3404 66.3443 ENSG00000176444 homo_sapiens ENSP00000357345 87.1743 76.7535 hippocampus_comes ENSHCOP00000017606 81.1567 71.4552 ENSG00000176444 homo_sapiens ENSP00000357345 55.3106 46.0922 hippocampus_comes ENSHCOP00000011704 83.8906 69.9088 ENSG00000176444 homo_sapiens ENSP00000357345 86.7735 77.9559 cyprinus_carpio_carpio ENSCCRP00000143230 82.6336 74.2366 ENSG00000176444 homo_sapiens ENSP00000357345 84.5691 75.7515 cyprinus_carpio_carpio ENSCCRP00000090254 79.4727 71.1864 ENSG00000176444 homo_sapiens ENSP00000357345 75.3507 64.7295 cyprinus_carpio_carpio ENSCCRP00000103831 82.0961 70.524 ENSG00000176444 homo_sapiens ENSP00000357345 93.7876 87.7756 coturnix_japonica ENSCJPP00005017421 93.4132 87.4251 ENSG00000176444 homo_sapiens ENSP00000357345 43.487 37.2745 poecilia_latipinna ENSPLAP00000006735 80.3704 68.8889 ENSG00000176444 homo_sapiens ENSP00000357345 87.1743 76.5531 poecilia_latipinna ENSPLAP00000023303 82.8571 72.7619 ENSG00000176444 homo_sapiens ENSP00000357345 83.1663 74.1483 sinocyclocheilus_grahami ENSSGRP00000060966 78.1544 69.6798 ENSG00000176444 homo_sapiens ENSP00000357345 79.3587 70.3407 sinocyclocheilus_grahami ENSSGRP00000110546 74.1573 65.7303 ENSG00000176444 homo_sapiens ENSP00000357345 74.3487 64.1283 sinocyclocheilus_grahami ENSSGRP00000039327 83.3708 71.9101 ENSG00000176444 homo_sapiens ENSP00000357345 87.976 77.3547 maylandia_zebra ENSMZEP00005035461 82.9868 72.9679 ENSG00000176444 homo_sapiens ENSP00000357345 43.6874 38.2766 maylandia_zebra ENSMZEP00005021465 82.8897 72.6236 ENSG00000176444 homo_sapiens ENSP00000357345 68.7375 60.3206 tetraodon_nigroviridis ENSTNIP00000020719 79.3981 69.6759 ENSG00000176444 homo_sapiens ENSP00000357345 56.7134 48.2966 tetraodon_nigroviridis ENSTNIP00000010891 79.7183 67.8873 ENSG00000176444 homo_sapiens ENSP00000357345 86.5731 76.5531 paramormyrops_kingsleyae ENSPKIP00000030050 81.9734 72.4858 ENSG00000176444 homo_sapiens ENSP00000357345 86.3727 77.9559 scleropages_formosus ENSSFOP00015061284 80.863 72.9831 ENSG00000176444 homo_sapiens ENSP00000357345 90.1804 82.3647 leptobrachium_leishanense ENSLLEP00000026056 89.6414 81.8725 ENSG00000176444 homo_sapiens ENSP00000357345 60.521 51.7034 scophthalmus_maximus ENSSMAP00000043932 77.635 66.3239 ENSG00000176444 homo_sapiens ENSP00000357345 86.7735 75.1503 scophthalmus_maximus ENSSMAP00000003872 71.6887 62.0861 ENSG00000176444 homo_sapiens ENSP00000357345 87.1743 75.1503 oryzias_melastigma ENSOMEP00000025699 83.174 71.7017 ENSG00000176444 homo_sapiens ENSP00000357345 51.1022 42.8858 oryzias_melastigma ENSOMEP00000008350 82.7922 69.4805
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0004674 enables protein serine/threonine kinase activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0004712 enables protein serine/threonine/tyrosine kinase activity 1 IEA Homo_sapiens(9606) Function GO:0004713 enables protein tyrosine kinase activity 1 IBA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005524 enables ATP binding 1 IEA Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 2 IBA,IDA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0006468 involved_in protein phosphorylation 1 IDA Homo_sapiens(9606) Process GO:0010212 involved_in response to ionizing radiation 1 IMP Homo_sapiens(9606) Process GO:0016604 located_in nuclear body 1 IDA Homo_sapiens(9606) Component GO:0016607 located_in nuclear speck 1 IEA Homo_sapiens(9606) Component GO:0018108 involved_in peptidyl-tyrosine phosphorylation 1 IBA Homo_sapiens(9606) Process GO:0042802 enables identical protein binding 1 IPI Homo_sapiens(9606) Function GO:0043484 involved_in regulation of RNA splicing 2 IBA,IDA Homo_sapiens(9606) Process GO:0045721 involved_in negative regulation of gluconeogenesis 1 ISS Homo_sapiens(9606) Process GO:0046777 involved_in protein autophosphorylation 1 ISS Homo_sapiens(9606) Process GO:0106310 enables protein serine kinase activity 1 IEA Homo_sapiens(9606) Function
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