Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlaviviruses
Drug N.A.
Main interacting RNAs snRNA
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000175467 Gene ID 9092 Accession 10538
Symbol SART1 Alias HAF;Ara1;HOMS1;Snu66;SART1259;SNRNP110 Full Name spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
Status Confidence Length 18409 bases Strand Plus strand
Position 11 : 65961729 - 65980137 RNA binding domain SART-1
Summary This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000310448 SART-1 PF03343 1.3e-136 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
25481564 The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing. Wenyu Lin 2015-05-01 Journal of hepatology
23749060 Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition. L John Goodier 2013-08-01 Nucleic acids research
31162605 Emerging roles of histone modifications and HDACs in RNA splicing. Raneen Rahhal 2019-06-04 Nucleic acids research

Transcripts

Name Transcript ID bp Protein Translation ID
SART1-207 ENST00000532333 873 No protein -
SART1-204 ENST00000529532 1471 No protein -
SART1-203 ENST00000528573 585 No protein -
SART1-206 ENST00000530251 753 164aa ENSP00000436218
SART1-201 ENST00000312397 3557 800aa ENSP00000310448
SART1-208 ENST00000533386 586 No protein -
SART1-205 ENST00000529580 390 No protein -
SART1-202 ENST00000528137 403 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000175467

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000175467homo_sapiensENSP0000031044895.62595.25nomascus_leucogenysENSNLEP0000000725298.582598.1959
ENSG00000175467homo_sapiensENSP0000031044810099.875pan_paniscusENSPPAP0000001425610099.875
ENSG00000175467homo_sapiensENSP0000031044899.87599.75pongo_abeliiENSPPYP0000000351799.87599.75
ENSG00000175467homo_sapiensENSP0000031044810099.875pan_troglodytesENSPTRP0000000673310099.875
ENSG00000175467homo_sapiensENSP0000031044810099.75gorilla_gorillaENSGGOP0000000924110099.75
ENSG00000175467homo_sapiensENSP000003104489085.5ornithorhynchus_anatinusENSOANP000000407359085.5
ENSG00000175467homo_sapiensENSP0000031044883.62579.75sarcophilus_harrisiiENSSHAP0000001337691.144486.921
ENSG00000175467homo_sapiensENSP0000031044887.12583.25notamacropus_eugeniiENSMEUP0000000450886.799582.939
ENSG00000175467homo_sapiensENSP0000031044839.37538.25choloepus_hoffmanniENSCHOP0000001004575.903673.7349
ENSG00000175467homo_sapiensENSP0000031044853.2550.75dasypus_novemcinctusENSDNOP0000002921178.45374.7698
ENSG00000175467homo_sapiensENSP0000031044898.2597.75callithrix_jacchusENSCJAP0000000313898.496297.995
ENSG00000175467homo_sapiensENSP0000031044899.37598.875cercocebus_atysENSCATP0000001828599.37598.875
ENSG00000175467homo_sapiensENSP0000031044895.594.375macaca_fascicularisENSMFAP0000000578784.794783.7958
ENSG00000175467homo_sapiensENSP0000031044899.37598.875macaca_mulattaENSMMUP0000006450699.37598.875
ENSG00000175467homo_sapiensENSP0000031044899.37598.875macaca_nemestrinaENSMNEP0000002403899.37598.875
ENSG00000175467homo_sapiensENSP0000031044899.37598.875papio_anubisENSPANP0000000238599.37598.875
ENSG00000175467homo_sapiensENSP0000031044890.7590.25mandrillus_leucophaeusENSMLEP0000002421099.588599.0398
ENSG00000175467homo_sapiensENSP0000031044892.7591.125tursiops_truncatusENSTTRP0000000832293.099191.468
ENSG00000175467homo_sapiensENSP0000031044897.62597vulpes_vulpesENSVVUP0000003784396.898396.2779
ENSG00000175467homo_sapiensENSP0000031044897.37595.25mus_spretusMGP_SPRETEiJ_P004955296.650194.5409
ENSG00000175467homo_sapiensENSP0000031044897.87597equus_asinusENSEASP0000500602696.786295.9209
ENSG00000175467homo_sapiensENSP000003104489593.375capra_hircusENSCHIP0000001596195.477493.8442
ENSG00000175467homo_sapiensENSP0000031044896.2594.875loxodonta_africanaENSLAFP0000000147696.2594.875
ENSG00000175467homo_sapiensENSP0000031044897.12596.375panthera_leoENSPLOP0000000995296.762196.0149
ENSG00000175467homo_sapiensENSP0000031044831.7530.125ailuropoda_melanoleucaENSAMEP0000001824283.006578.7582
ENSG00000175467homo_sapiensENSP0000031044896.87595.375bos_indicus_hybridENSBIXP0000501281096.633495.1372
ENSG00000175467homo_sapiensENSP0000031044897.87597equus_caballusENSECAP0000008479778.456977.7555
ENSG00000175467homo_sapiensENSP0000031044897.37596.75canis_lupus_familiarisENSCAFP0084502021196.650196.0298
ENSG00000175467homo_sapiensENSP0000031044895.7595.125panthera_pardusENSPPRP0000002548698.079497.4392
ENSG00000175467homo_sapiensENSP000003104488482.375marmota_marmota_marmotaENSMMMP0000002447994.38292.5562
ENSG00000175467homo_sapiensENSP0000031044896.62594.5balaenoptera_musculusENSBMSP0001001351696.024893.913
ENSG00000175467homo_sapiensENSP0000031044883.2581.375cavia_porcellusENSCPOP0000001511296.661894.4848
ENSG00000175467homo_sapiensENSP000003104489796.5felis_catusENSFCAP0000004786096.637696.1395
ENSG00000175467homo_sapiensENSP0000031044891.87591.125ursus_americanusENSUAMP0000002686396.078495.2941
ENSG00000175467homo_sapiensENSP0000031044887.12584.875bison_bison_bisonENSBBBP0000002828792.809690.4128
ENSG00000175467homo_sapiensENSP0000031044896.12594.25monodon_monocerosENSMMNP0001502215195.765993.8979
ENSG00000175467homo_sapiensENSP0000031044897.12595.75sus_scrofaENSSSCP0000001378396.762195.3923
ENSG00000175467homo_sapiensENSP0000031044897.62596.625microcebus_murinusENSMICP0000001973196.778295.7869
ENSG00000175467homo_sapiensENSP0000031044897.596octodon_degusENSODEP0000002429596.774295.2854
ENSG00000175467homo_sapiensENSP0000031044896.87595.125jaculus_jaculusENSJJAP0000001764095.915894.1832
ENSG00000175467homo_sapiensENSP0000031044896.87595.5ovis_aries_rambouilletENSOARP0002002817197.361895.9799
ENSG00000175467homo_sapiensENSP0000031044873.87572.375ursus_maritimusENSUMAP0000001489993.809591.9048
ENSG00000175467homo_sapiensENSP0000031044844.87543.75ochotona_princepsENSOPRP0000001182251.654750.3597
ENSG00000175467homo_sapiensENSP0000031044896.12594.25delphinapterus_leucasENSDLEP0000000393395.765993.8979
ENSG00000175467homo_sapiensENSP0000031044896.2593.75physeter_catodonENSPCTP0000503186996.129893.633
ENSG00000175467homo_sapiensENSP0000031044897.12595mus_caroliMGP_CAROLIEiJ_P004758996.40294.2928
ENSG00000175467homo_sapiensENSP0000031044897.37595.25mus_musculusENSMUSP0000004739796.650194.5409
ENSG00000175467homo_sapiensENSP0000031044889.587.25dipodomys_ordiiENSDORP0000002754692.746190.4145
ENSG00000175467homo_sapiensENSP0000031044897.2596.5mustela_putorius_furoENSMPUP0000001130296.886796.1395
ENSG00000175467homo_sapiensENSP0000031044894.7593.375aotus_nancymaaeENSANAP0000003973886.529785.274
ENSG00000175467homo_sapiensENSP0000031044897.62597.25saimiri_boliviensis_boliviensisENSSBOP0000001273998.611198.2323
ENSG00000175467homo_sapiensENSP0000031044899.599.125chlorocebus_sabaeusENSCSAP0000000434299.599.125
ENSG00000175467homo_sapiensENSP0000031044857.12551.25tupaia_belangeriENSTBEP0000000895585.261276.4925
ENSG00000175467homo_sapiensENSP0000031044857.7556.5tupaia_belangeriENSTBEP0000000941564.615463.2168
ENSG00000175467homo_sapiensENSP0000031044877.37569.5tupaia_belangeriENSTBEP0000000207482.75474.3316
ENSG00000175467homo_sapiensENSP0000031044897.7595.75mesocricetus_auratusENSMAUP0000001743997.022395.0372
ENSG00000175467homo_sapiensENSP0000031044896.12594.125phocoena_sinusENSPSNP0000001704495.765993.7734
ENSG00000175467homo_sapiensENSP0000031044896.12594.75camelus_dromedariusENSCDRP0000502577495.646894.2786
ENSG00000175467homo_sapiensENSP0000031044879.62576.375carlito_syrichtaENSTSYP0000002782791.919288.1674
ENSG00000175467homo_sapiensENSP000003104486360panthera_tigris_altaicaENSPTIP0000002032487.348483.1889
ENSG00000175467homo_sapiensENSP0000031044897.12595rattus_norvegicusENSRNOP0000002781296.40294.2928
ENSG00000175467homo_sapiensENSP0000031044893.593prolemur_simusENSPSMP0000003269895.5395.0192
ENSG00000175467homo_sapiensENSP0000031044897.87596.125microtus_ochrogasterENSMOCP0000002295297.267195.528
ENSG00000175467homo_sapiensENSP000003104489189peromyscus_maniculatus_bairdiiENSPEMP0000001156390.322688.3375
ENSG00000175467homo_sapiensENSP0000031044895.12593.625bos_mutusENSBMUP0000000093095.244193.7422
ENSG00000175467homo_sapiensENSP0000031044897.595.25mus_spicilegusENSMSIP0000000406496.774294.5409
ENSG00000175467homo_sapiensENSP000003104489896cricetulus_griseus_chok1gshdENSCGRP0000102305097.149995.1673
ENSG00000175467homo_sapiensENSP000003104489089pteropus_vampyrusENSPVAP0000001600691.02490.0126
ENSG00000175467homo_sapiensENSP0000031044895.7594.5myotis_lucifugusENSMLUP0000001011395.037293.7965
ENSG00000175467homo_sapiensENSP0000031044892.2589vombatus_ursinusENSVURP0001000146791.67788.4472
ENSG00000175467homo_sapiensENSP0000031044895.87594.375rhinolophus_ferrumequinumENSRFEP0001000423495.161393.6725
ENSG00000175467homo_sapiensENSP0000031044897.2596.125neovison_visonENSNVIP0000001939196.886795.7659
ENSG00000175467homo_sapiensENSP0000031044896.7595.25bos_taurusENSBTAP0000000402796.508795.0125
ENSG00000175467homo_sapiensENSP0000031044896.62594.5heterocephalus_glaber_femaleENSHGLP0000002102494.730492.6471
ENSG00000175467homo_sapiensENSP0000031044899.12598.75rhinopithecus_bietiENSRBIP0000004151099.12598.75
ENSG00000175467homo_sapiensENSP0000031044897.37596.75canis_lupus_dingoENSCAFP0002001928996.650196.0298
ENSG00000175467homo_sapiensENSP0000031044897.596.25sciurus_vulgarisENSSVLP0000501096597.86796.6123
ENSG00000175467homo_sapiensENSP0000031044891.37587.25phascolarctos_cinereusENSPCIP0000001022091.834287.6884
ENSG00000175467homo_sapiensENSP0000031044863.561.375procavia_capensisENSPCAP0000001057162.871360.7673
ENSG00000175467homo_sapiensENSP0000031044893.2591.375nannospalax_galiliENSNGAP0000000388496.382494.4444
ENSG00000175467homo_sapiensENSP0000031044897.7596chinchilla_lanigeraENSCLAP0000002417697.022395.2854
ENSG00000175467homo_sapiensENSP0000031044896.7595.375cervus_hanglu_yarkandensisENSCHYP0000000059693.028891.7067
ENSG00000175467homo_sapiensENSP0000031044896.7595.5catagonus_wagneriENSCWAP0000001795496.388595.1432
ENSG00000175467homo_sapiensENSP0000031044898.12596.375ictidomys_tridecemlineatusENSSTOP0000002641697.636895.8955
ENSG00000175467homo_sapiensENSP0000031044897.87596.875otolemur_garnettiiENSOGAP0000001478897.752896.7541
ENSG00000175467homo_sapiensENSP0000031044898.2598.125cebus_imitatorENSCCAP0000004009198.496298.3709
ENSG00000175467homo_sapiensENSP0000031044898.12596.5urocitellus_parryiiENSUPAP0001001126597.636896.0199
ENSG00000175467homo_sapiensENSP0000031044896.594.75moschus_moschiferusENSMMSP0000001218096.259494.5137
ENSG00000175467homo_sapiensENSP0000031044899.12598.75rhinopithecus_roxellanaENSRROP0000004458799.12598.75
ENSG00000175467homo_sapiensENSP0000031044897.12595mus_pahariMGP_PahariEiJ_P002060296.40294.2928
ENSG00000175467homo_sapiensENSP0000031044897.62596.75propithecus_coquereliENSPCOP0000000276497.992597.1142
ENSG00000175467homo_sapiensENSP0000031044846.7530.875caenorhabditis_elegansF19F10.9.145.114629.7949
ENSG00000175467homo_sapiensENSP0000031044856.2538.375drosophila_melanogasterFBpp008853746.391831.6495
ENSG00000175467homo_sapiensENSP0000031044857.12536.125ciona_intestinalisENSCINP0000001837056.982536.0349
ENSG00000175467homo_sapiensENSP0000031044838.530.125petromyzon_marinusENSPMAP0000000606773.508457.5179
ENSG00000175467homo_sapiensENSP0000031044849.7538.875eptatretus_burgeriENSEBUP0000000965568.034253.1624
ENSG00000175467homo_sapiensENSP0000031044865.2556.875latimeria_chalumnaeENSLACP0000001267280.431470.1079
ENSG00000175467homo_sapiensENSP0000031044814.7512.5lepisosteus_oculatusENSLOCP0000000214669.411858.8235
ENSG00000175467homo_sapiensENSP0000031044851.12545lepisosteus_oculatusENSLOCP0000000216381.872
ENSG00000175467homo_sapiensENSP0000031044877.2565.5carassius_auratusENSCARP0000013358480.051867.8756
ENSG00000175467homo_sapiensENSP0000031044877.87564.75ictalurus_punctatusENSIPUP0000003140378.960765.6527
ENSG00000175467homo_sapiensENSP0000031044876.563.625electrophorus_electricusENSEEEP0000000396877.862664.7583
ENSG00000175467homo_sapiensENSP0000031044876.564.125oncorhynchus_kisutchENSOKIP0000509105378.160965.5172
ENSG00000175467homo_sapiensENSP0000031044876.564.125oncorhynchus_mykissENSOMYP0000007126477.961865.3503
ENSG00000175467homo_sapiensENSP0000031044876.62564.25salmo_salarENSSSAP0000009115277.989865.3944
ENSG00000175467homo_sapiensENSP0000031044876.62564.25salmo_truttaENSSTUP0000005552977.989865.3944
ENSG00000175467homo_sapiensENSP0000031044876.7563gadus_morhuaENSGMOP0000003738280.471866.055
ENSG00000175467homo_sapiensENSP0000031044876.87564.75fundulus_heteroclitusENSFHEP0000000911179.560267.0116
ENSG00000175467homo_sapiensENSP0000031044874.87563.5poecilia_reticulataENSPREP0000000010079.232867.1958
ENSG00000175467homo_sapiensENSP0000031044876.87564oryzias_latipesENSORLP0000003308980.602967.1035
ENSG00000175467homo_sapiensENSP000003104487662.375cyclopterus_lumpusENSCLMP0000503190578.858664.7211
ENSG00000175467homo_sapiensENSP0000031044878.2566.875oreochromis_niloticusENSONIP0000002658581.404469.5709
ENSG00000175467homo_sapiensENSP0000031044842.87533.5haplochromis_burtoniENSHBUP0000003323064.473750.3759
ENSG00000175467homo_sapiensENSP0000031044849.7541.375lates_calcariferENSLCAP0001003780678.811965.5446
ENSG00000175467homo_sapiensENSP0000031044885.7578chrysemys_picta_belliiENSCPBP0000003351283.863176.2836
ENSG00000175467homo_sapiensENSP0000031044884.62577.5sphenodon_punctatusENSSPUP0000001223784.20477.1144
ENSG00000175467homo_sapiensENSP000003104488475laticauda_laticaudataENSLLTP0000001309981.751872.9927
ENSG00000175467homo_sapiensENSP0000031044845.7538.625pseudonaja_textilisENSPTXP0000002448674.541762.9328
ENSG00000175467homo_sapiensENSP0000031044841.62533.625anolis_carolinensisENSACAP0000001799965.680553.0572
ENSG00000175467homo_sapiensENSP0000031044884.12575.125naja_najaENSNNAP0000000593381.77473.0255
ENSG00000175467homo_sapiensENSP000003104488576.625podarcis_muralisENSPMRP0000002669082.125674.0338
ENSG00000175467homo_sapiensENSP0000031044872.2562taeniopygia_guttataENSTGUP0000002549972.52262.2334
ENSG00000175467homo_sapiensENSP0000031044885.2576salvator_merianaeENSSMRP0000001396681.093972.2949
ENSG00000175467homo_sapiensENSP0000031044876.7564.875oryzias_javanicusENSOJAP0000002366680.366567.9319
ENSG00000175467homo_sapiensENSP0000031044878.2566.125dicentrarchus_labraxENSDLAP0000505554880.153667.7337
ENSG00000175467homo_sapiensENSP0000031044876.563.625oryzias_sinensisENSOSIP0000003520480.209766.7104
ENSG00000175467homo_sapiensENSP0000031044883.12575.25pelodiscus_sinensisENSPSIP0000000278982.506274.6898
ENSG00000175467homo_sapiensENSP0000031044870.7562.75gopherus_evgoodeiENSGEVP0000502171086.412276.6412
ENSG00000175467homo_sapiensENSP0000031044885.62578.25chelonoidis_abingdoniiENSCABP0000000049684.359677.0936
ENSG00000175467homo_sapiensENSP0000031044876.62565.625seriola_dumeriliENSSDUP0000002636683.062371.1382
ENSG00000175467homo_sapiensENSP0000031044877.7564.25cottoperca_gobioENSCGOP0000003642380.361866.4083
ENSG00000175467homo_sapiensENSP000003104487662.25gasterosteus_aculeatusENSGACP0000002239478.96164.6753
ENSG00000175467homo_sapiensENSP0000031044876.565.125poecilia_formosaENSPFOP0000002001079.274667.487
ENSG00000175467homo_sapiensENSP000003104487764.75sander_luciopercaENSSLUP0000000852779.483966.8387
ENSG00000175467homo_sapiensENSP0000031044833.87527.625strigops_habroptilaENSSHBP0000500941855.532845.2869
ENSG00000175467homo_sapiensENSP0000031044885.7578.125terrapene_carolina_triunguisENSTMTP0000000035883.556676.1267
ENSG00000175467homo_sapiensENSP0000031044876.7564.25hucho_huchoENSHHUP0000008286578.017865.3113
ENSG00000175467homo_sapiensENSP0000031044877.37565.125hucho_huchoENSHHUP0000004092779.257466.7094
ENSG00000175467homo_sapiensENSP000003104485736.625ciona_savignyiENSCSAVP0000001587958.762937.7577
ENSG00000175467homo_sapiensENSP000003104487866.25seriola_lalandi_dorsalisENSSLDP0000003164580.933968.7419
ENSG00000175467homo_sapiensENSP0000031044878.567pundamilia_nyerereiENSPNYP0000001953781.664569.7009
ENSG00000175467homo_sapiensENSP0000031044877.62566.375stegastes_partitusENSSPAP0000001743380.544768.8716
ENSG00000175467homo_sapiensENSP0000031044876.62564.375oncorhynchus_tshawytschaENSOTSP0000506488378.089265.6051
ENSG00000175467homo_sapiensENSP0000031044872.2564.25aquila_chrysaetos_chrysaetosENSACCP0002001206276.964168.4421
ENSG00000175467homo_sapiensENSP0000031044876.7565.25cyprinodon_variegatusENSCVAP0000000805779.636867.7043
ENSG00000175467homo_sapiensENSP0000031044877.62564.625denticeps_clupeoidesENSDCDP0000000467179.717666.3671
ENSG00000175467homo_sapiensENSP0000031044875.563.625takifugu_rubripesENSTRUP0000004945878.238365.9326
ENSG00000175467homo_sapiensENSP0000031044876.12564.5hippocampus_comesENSHCOP0000000557777.97766.0691
ENSG00000175467homo_sapiensENSP000003104487865.625cyprinus_carpio_carpioENSCCRP0000009033380.724467.9172
ENSG00000175467homo_sapiensENSP0000031044876.12565.125poecilia_latipinnaENSPLAP0000002942678.88667.487
ENSG00000175467homo_sapiensENSP0000031044877.62565.875sinocyclocheilus_grahamiENSSGRP0000002314280.336368.1759
ENSG00000175467homo_sapiensENSP000003104483629.5sinocyclocheilus_grahamiENSSGRP0000000532576.862.9333
ENSG00000175467homo_sapiensENSP000003104487967.125scleropages_formosusENSSFOP0001504472778.024766.2963
ENSG00000175467homo_sapiensENSP0000031044876.87564.5scophthalmus_maximusENSSMAP0000000164878.544165.9004
ENSG00000175467homo_sapiensENSP0000031044877.2564.875oryzias_melastigmaENSOMEP0000002278580.996168.021

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000387involved_in spliceosomal snRNP assembly1TASHomo_sapiens(9606)Process
GO:0000398involved_in mRNA splicing, via spliceosome3IC,IDA,NASHomo_sapiens(9606)Process
GO:0000481involved_in maturation of 5S rRNA1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus2IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1TASHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0015030located_in Cajal body1IDAHomo_sapiens(9606)Component
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0045292involved_in mRNA cis splicing, via spliceosome1IBAHomo_sapiens(9606)Process
GO:0045585involved_in positive regulation of cytotoxic T cell differentiation1IDAHomo_sapiens(9606)Process
GO:0046540part_of U4/U6 x U5 tri-snRNP complex2IBA,IPIHomo_sapiens(9606)Component
GO:0071005part_of U2-type precatalytic spliceosome1IDAHomo_sapiens(9606)Component
GO:0071013part_of catalytic step 2 spliceosome1IDAHomo_sapiens(9606)Component

Expression