Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000172757 Gene ID 1072 Accession 1874
Symbol CFL1 Alias CFL;cofilin;HEL-S-15 Full Name cofilin 1
Status Confidence Length 7354 bases Strand Minus strand
Position 11 : 65854673 - 65862026 RNA binding domain N.A.
Summary The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
CFL1-208 ENST00000530157 1082 No protein -
CFL1-207 ENST00000527752 766 No protein -
CFL1-204 ENST00000525710 761 No protein -
CFL1-201 ENST00000308162 1245 166aa ENSP00000309629
CFL1-203 ENST00000525451 1878 166aa ENSP00000432660
CFL1-210 ENST00000530945 1509 No protein -
CFL1-206 ENST00000527344 962 149aa ENSP00000432155
CFL1-211 ENST00000531407 1062 149aa ENSP00000433910
CFL1-202 ENST00000524553 860 149aa ENSP00000432226
CFL1-214 ENST00000534769 758 204aa ENSP00000431696
CFL1-212 ENST00000531413 636 149aa ENSP00000433131
CFL1-213 ENST00000532134 855 159aa ENSP00000436431
CFL1-209 ENST00000530413 647 122aa ENSP00000436899
CFL1-215 ENST00000534784 737 79aa ENSP00000433308
CFL1-205 ENST00000526975 567 90aa ENSP00000432153

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000172757homo_sapiensENSP0000024606985.454571.5152homo_sapiensENSP0000030962984.939871.0843
ENSG00000172757homo_sapiensENSP0000029815989.75980.7229homo_sapiensENSP0000030962989.75980.7229

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000172757homo_sapiensENSP0000030962986.144681.9277nomascus_leucogenysENSNLEP0000003464868.095264.7619
ENSG00000172757homo_sapiensENSP0000030962986.74780.7229nomascus_leucogenysENSNLEP0000004824087.804981.7073
ENSG00000172757homo_sapiensENSP0000030962983.132580.1205nomascus_leucogenysENSNLEP0000003553473.015970.3704
ENSG00000172757homo_sapiensENSP0000030962975.903672.2892pan_paniscusENSPPAP0000003131962.376259.4059
ENSG00000172757homo_sapiensENSP0000030962987.951884.3373pan_paniscusENSPPAP0000001783969.194366.3507
ENSG00000172757homo_sapiensENSP0000030962978.915774.6988pan_paniscusENSPPAP0000003895487.919583.2215
ENSG00000172757homo_sapiensENSP00000309629100100pongo_abeliiENSPPYP00000003525100100
ENSG00000172757homo_sapiensENSP0000030962975.301271.6867pan_troglodytesENSPTRP0000007742861.881258.9109
ENSG00000172757homo_sapiensENSP0000030962978.915774.6988pan_troglodytesENSPTRP0000009177187.919583.2215
ENSG00000172757homo_sapiensENSP0000030962987.951883.7349pan_troglodytesENSPTRP0000006622069.194365.8768
ENSG00000172757homo_sapiensENSP0000030962986.144681.9277gorilla_gorillaENSGGOP0000004922367.772564.455
ENSG00000172757homo_sapiensENSP0000030962979.518175.3012gorilla_gorillaENSGGOP0000004445788.590683.8926
ENSG00000172757homo_sapiensENSP0000030962999.397698.1928ornithorhynchus_anatinusENSOANP0000004188999.397698.1928
ENSG00000172757homo_sapiensENSP0000030962998.795296.988sarcophilus_harrisiiENSSHAP0000004522998.795296.988
ENSG00000172757homo_sapiensENSP0000030962990.361485.5422notamacropus_eugeniiENSMEUP0000000671093.167788.1988
ENSG00000172757homo_sapiensENSP0000030962997.590497.5904dasypus_novemcinctusENSDNOP0000002600097.590497.5904
ENSG00000172757homo_sapiensENSP0000030962979.518174.6988callithrix_jacchusENSCJAP0000007156285.714380.5195
ENSG00000172757homo_sapiensENSP0000030962991.566387.3494cercocebus_atysENSCATP0000001998381.283477.5401
ENSG00000172757homo_sapiensENSP0000030962980.120574.0964macaca_fascicularisENSMFAP0000001220988.079581.457
ENSG00000172757homo_sapiensENSP0000030962984.939881.3253macaca_fascicularisENSMFAP0000003410994.630990.604
ENSG00000172757homo_sapiensENSP0000030962990.963987.3494macaca_nemestrinaENSMNEP0000004120272.248869.378
ENSG00000172757homo_sapiensENSP0000030962986.144681.3253papio_anubisENSPANP0000004296695.973290.604
ENSG00000172757homo_sapiensENSP0000030962978.915774.6988papio_anubisENSPANP0000003567490.344885.5172
ENSG00000172757homo_sapiensENSP0000030962992.168787.9518mandrillus_leucophaeusENSMLEP0000003320973.205769.8565
ENSG00000172757homo_sapiensENSP0000030962984.337377.1084mandrillus_leucophaeusENSMLEP0000000577688.607681.0127
ENSG00000172757homo_sapiensENSP0000030962984.337377.7108mandrillus_leucophaeusENSMLEP0000000381288.607681.6456
ENSG00000172757homo_sapiensENSP0000030962998.192898.1928tursiops_truncatusENSTTRP0000001605198.192898.1928
ENSG00000172757homo_sapiensENSP0000030962910099.3976vulpes_vulpesENSVVUP0000004099584.693984.1837
ENSG00000172757homo_sapiensENSP0000030962999.397698.7952mus_spretusMGP_SPRETEiJ_P004959699.397698.7952
ENSG00000172757homo_sapiensENSP0000030962996.98895.7831loxodonta_africanaENSLAFP0000001686171.238970.354
ENSG00000172757homo_sapiensENSP00000309629100100ailuropoda_melanoleucaENSAMEP00000018309100100
ENSG00000172757homo_sapiensENSP0000030962983.132581.3253canis_lupus_familiarisENSCAFP0084502111793.243291.2162
ENSG00000172757homo_sapiensENSP0000030962987.349485.5422canis_lupus_familiarisENSCAFP0084501732191.19589.3082
ENSG00000172757homo_sapiensENSP0000030962986.144685.5422canis_lupus_familiarisENSCAFP0084500118769.082168.599
ENSG00000172757homo_sapiensENSP0000030962980.120569.2771panthera_pardusENSPPRP0000000370872.282662.5
ENSG00000172757homo_sapiensENSP0000030962999.397699.3976marmota_marmota_marmotaENSMMMP0000000628899.397699.3976
ENSG00000172757homo_sapiensENSP00000309629100100marmota_marmota_marmotaENSMMMP00000024137100100
ENSG00000172757homo_sapiensENSP0000030962977.710872.2892balaenoptera_musculusENSBMSP0001002492666.494861.8557
ENSG00000172757homo_sapiensENSP00000309629100100ursus_americanusENSUAMP00000026879100100
ENSG00000172757homo_sapiensENSP0000030962986.74781.3253monodon_monocerosENSMMNP0001501369674.611469.9482
ENSG00000172757homo_sapiensENSP0000030962972.289265.0602sus_scrofaENSSSCP0000005918663.157956.8421
ENSG00000172757homo_sapiensENSP0000030962987.349480.7229octodon_degusENSODEP0000001944391.772184.8101
ENSG00000172757homo_sapiensENSP00000309629100100ursus_maritimusENSUMAP00000014678100100
ENSG00000172757homo_sapiensENSP0000030962986.74780.7229delphinapterus_leucasENSDLEP0000000337374.611469.4301
ENSG00000172757homo_sapiensENSP0000030962974.096471.0843physeter_catodonENSPCTP0000502748884.246680.8219
ENSG00000172757homo_sapiensENSP0000030962999.397698.7952mus_caroliMGP_CAROLIEiJ_P004763499.397698.7952
ENSG00000172757homo_sapiensENSP0000030962999.397698.7952mus_musculusENSMUSP0000011225972.687272.2467
ENSG00000172757homo_sapiensENSP0000030962977.710873.494aotus_nancymaaeENSANAP0000000284689.583384.7222
ENSG00000172757homo_sapiensENSP0000030962976.50672.8916aotus_nancymaaeENSANAP0000002673789.436685.2113
ENSG00000172757homo_sapiensENSP0000030962986.74785.5422aotus_nancymaaeENSANAP0000000108667.924566.9811
ENSG00000172757homo_sapiensENSP0000030962983.132578.3133saimiri_boliviensis_boliviensisENSSBOP0000000935687.898182.8026
ENSG00000172757homo_sapiensENSP0000030962985.542283.1325saimiri_boliviensis_boliviensisENSSBOP0000002280068.59966.6667
ENSG00000172757homo_sapiensENSP0000030962976.50676.506vicugna_pacosENSVPAP0000000419298.449698.4496
ENSG00000172757homo_sapiensENSP0000030962998.192898.1928tupaia_belangeriENSTBEP0000001456091.57391.573
ENSG00000172757homo_sapiensENSP0000030962999.397699.3976mesocricetus_auratusENSMAUP0000001973599.397699.3976
ENSG00000172757homo_sapiensENSP0000030962986.74780.7229phocoena_sinusENSPSNP0000002460474.611469.4301
ENSG00000172757homo_sapiensENSP0000030962986.144684.3373camelus_dromedariusENSCDRP0000502662569.417567.9612
ENSG00000172757homo_sapiensENSP0000030962987.349486.1446carlito_syrichtaENSTSYP0000002963987.349486.1446
ENSG00000172757homo_sapiensENSP0000030962984.939883.1325carlito_syrichtaENSTSYP0000002868670.854369.3467
ENSG00000172757homo_sapiensENSP0000030962987.951886.1446carlito_syrichtaENSTSYP0000001628469.523868.0952
ENSG00000172757homo_sapiensENSP0000030962989.75989.1566carlito_syrichtaENSTSYP0000001537462.343161.9247
ENSG00000172757homo_sapiensENSP0000030962987.349486.1446carlito_syrichtaENSTSYP0000001559553.703752.963
ENSG00000172757homo_sapiensENSP0000030962978.915777.7108microtus_ochrogasterENSMOCP0000000500690.344888.9655
ENSG00000172757homo_sapiensENSP0000030962992.168791.5663microtus_ochrogasterENSMOCP0000002680878.86678.3505
ENSG00000172757homo_sapiensENSP0000030962991.566387.9518peromyscus_maniculatus_bairdiiENSPEMP0000003423879.166776.0417
ENSG00000172757homo_sapiensENSP0000030962990.361488.5542mus_spicilegusENSMSIP0000001544879.365177.7778
ENSG00000172757homo_sapiensENSP0000030962996.98896.988cricetulus_griseus_chok1gshdENSCGRP0000102187780.904580.9045
ENSG00000172757homo_sapiensENSP00000309629100100pteropus_vampyrusENSPVAP00000015993100100
ENSG00000172757homo_sapiensENSP0000030962998.192896.988vombatus_ursinusENSVURP0001000175198.192896.988
ENSG00000172757homo_sapiensENSP00000309629100100rhinolophus_ferrumequinumENSRFEP00010004930100100
ENSG00000172757homo_sapiensENSP0000030962998.795298.1928neovison_visonENSNVIP0000001974282.412181.9095
ENSG00000172757homo_sapiensENSP0000030962992.168790.3614neovison_visonENSNVIP0000000240896.226494.3396
ENSG00000172757homo_sapiensENSP0000030962971.084367.4699rhinopithecus_bietiENSRBIP0000001822594.489.6
ENSG00000172757homo_sapiensENSP0000030962986.144685.5422canis_lupus_dingoENSCAFP0002001515169.082168.599
ENSG00000172757homo_sapiensENSP0000030962980.722978.3133canis_lupus_dingoENSCAFP0002000298282.208679.7546
ENSG00000172757homo_sapiensENSP00000309629100100sciurus_vulgarisENSSVLP00005011793100100
ENSG00000172757homo_sapiensENSP0000030962998.795297.5904phascolarctos_cinereusENSPCIP0000001007698.795297.5904
ENSG00000172757homo_sapiensENSP0000030962975.301274.6988procavia_capensisENSPCAP0000000984597.656296.875
ENSG00000172757homo_sapiensENSP0000030962990.963985.5422procavia_capensisENSPCAP0000000636991.515286.0606
ENSG00000172757homo_sapiensENSP0000030962998.795298.1928nannospalax_galiliENSNGAP0000000300398.795298.1928
ENSG00000172757homo_sapiensENSP0000030962994.578393.3735ictidomys_tridecemlineatusENSSTOP0000002005298.12596.875
ENSG00000172757homo_sapiensENSP0000030962998.192897.5904cebus_imitatorENSCCAP0000001517910099.3865
ENSG00000172757homo_sapiensENSP0000030962996.385593.9759urocitellus_parryiiENSUPAP0001000719278.431476.4706
ENSG00000172757homo_sapiensENSP0000030962977.710877.1084rhinopithecus_roxellanaENSRROP0000004308286.577285.906
ENSG00000172757homo_sapiensENSP0000030962981.927775.9036rhinopithecus_roxellanaENSRROP0000000252586.07679.7468
ENSG00000172757homo_sapiensENSP0000030962976.50671.6867rhinopithecus_roxellanaENSRROP0000004547268.648764.3243
ENSG00000172757homo_sapiensENSP0000030962999.397698.7952mus_pahariMGP_PahariEiJ_P002064599.397698.7952
ENSG00000172757homo_sapiensENSP0000030962981.927774.6988propithecus_coquereliENSPCOP0000000212591.275283.2215
ENSG00000172757homo_sapiensENSP0000030962945.180723.494caenorhabditis_elegansC38C3.5.149.342125.6579
ENSG00000172757homo_sapiensENSP0000030962945.180727.1084caenorhabditis_elegansF53E2.2.145.454527.2727
ENSG00000172757homo_sapiensENSP0000030962946.385524.6988drosophila_melanogasterFBpp007437852.02727.7027
ENSG00000172757homo_sapiensENSP0000030962949.397631.3253drosophila_melanogasterFBpp007209755.405435.1351
ENSG00000172757homo_sapiensENSP0000030962946.385526.506ciona_intestinalisENSCINP0000003339746.385526.506
ENSG00000172757homo_sapiensENSP0000030962945.783122.2892ciona_intestinalisENSCINP0000000459344.444421.6374
ENSG00000172757homo_sapiensENSP0000030962982.530170.4819clupea_harengusENSCHAP0000001866283.030370.9091
ENSG00000172757homo_sapiensENSP0000030962983.734974.6988clupea_harengusENSCHAP0000000743985.276176.0736
ENSG00000172757homo_sapiensENSP0000030962984.939874.6988danio_rerioENSDARP0000002317785.454575.1515
ENSG00000172757homo_sapiensENSP0000030962981.927771.0843carassius_auratusENSCARP0000006393082.424271.5152
ENSG00000172757homo_sapiensENSP0000030962979.518168.0723carassius_auratusENSCARP0000008539160.550551.8349
ENSG00000172757homo_sapiensENSP0000030962983.132574.6988carassius_auratusENSCARP0000003107081.656873.3728
ENSG00000172757homo_sapiensENSP0000030962984.337374.0964astyanax_mexicanusENSAMXP0000002835472.916764.0625
ENSG00000172757homo_sapiensENSP0000030962984.337374.6988ictalurus_punctatusENSIPUP0000003224484.848575.1515
ENSG00000172757homo_sapiensENSP0000030962987.349478.9157esox_luciusENSELUP0000006608586.826378.4431
ENSG00000172757homo_sapiensENSP0000030962974.096463.253electrophorus_electricusENSEEEP0000004210771.511661.0465
ENSG00000172757homo_sapiensENSP0000030962978.313370.4819oncorhynchus_kisutchENSOKIP0000510391386.666778
ENSG00000172757homo_sapiensENSP0000030962986.74777.1084oncorhynchus_kisutchENSOKIP0000510526986.227576.6467
ENSG00000172757homo_sapiensENSP0000030962986.74777.7108oncorhynchus_kisutchENSOKIP0000507153086.227577.2455
ENSG00000172757homo_sapiensENSP0000030962986.144676.506oncorhynchus_mykissENSOMYP0000013353772.959264.7959
ENSG00000172757homo_sapiensENSP0000030962986.144677.1084oncorhynchus_mykissENSOMYP0000008409386.144677.1084
ENSG00000172757homo_sapiensENSP0000030962986.144677.1084salmo_salarENSSSAP0000015958481.2572.7273
ENSG00000172757homo_sapiensENSP0000030962986.74777.7108salmo_salarENSSSAP0000002394086.227577.2455
ENSG00000172757homo_sapiensENSP0000030962986.74777.1084salmo_salarENSSSAP0000017191356.91750.5929
ENSG00000172757homo_sapiensENSP0000030962986.74777.1084salmo_truttaENSSTUP0000003967086.227576.6467
ENSG00000172757homo_sapiensENSP0000030962986.74777.7108salmo_truttaENSSTUP0000006232986.227577.2455
ENSG00000172757homo_sapiensENSP0000030962986.74777.7108salmo_truttaENSSTUP0000008755086.227577.2455
ENSG00000172757homo_sapiensENSP0000030962987.349479.5181gadus_morhuaENSGMOP0000000347778.804371.7391
ENSG00000172757homo_sapiensENSP0000030962987.349475.3012fundulus_heteroclitusENSFHEP0000001371686.826374.8503
ENSG00000172757homo_sapiensENSP0000030962986.74774.6988poecilia_reticulataENSPREP000000128928068.8889
ENSG00000172757homo_sapiensENSP0000030962987.349474.6988xiphophorus_maculatusENSXMAP0000001315468.720458.7678
ENSG00000172757homo_sapiensENSP0000030962986.144674.6988oryzias_latipesENSORLP0000000261785.628774.2515
ENSG00000172757homo_sapiensENSP0000030962987.349474.0964cyclopterus_lumpusENSCLMP0000501980086.826373.6527
ENSG00000172757homo_sapiensENSP0000030962978.915769.2771oreochromis_niloticusENSONIP0000000684887.333376.6667
ENSG00000172757homo_sapiensENSP0000030962987.349477.1084haplochromis_burtoniENSHBUP0000001165086.826376.6467
ENSG00000172757homo_sapiensENSP0000030962987.349477.1084astatotilapia_callipteraENSACLP0000002705386.826376.6467
ENSG00000172757homo_sapiensENSP0000030962986.144671.6867sparus_aurataENSSAUP0001000543464.705953.8462
ENSG00000172757homo_sapiensENSP0000030962987.349476.506lates_calcariferENSLCAP0001004258886.826376.0479
ENSG00000172757homo_sapiensENSP0000030962982.530177.7108xenopus_tropicalisENSXETP0000011192764.622660.8491
ENSG00000172757homo_sapiensENSP0000030962996.98891.5663chrysemys_picta_belliiENSCPBP0000003345463.888960.3175
ENSG00000172757homo_sapiensENSP0000030962987.951886.1446sphenodon_punctatusENSSPUP0000001054597.986695.9732
ENSG00000172757homo_sapiensENSP0000030962986.74780.7229laticauda_laticaudataENSLLTP0000001684786.74780.7229
ENSG00000172757homo_sapiensENSP0000030962986.74779.5181notechis_scutatusENSNSUP0000000701486.74779.5181
ENSG00000172757homo_sapiensENSP0000030962986.74779.5181pseudonaja_textilisENSPTXP0000001591786.74779.5181
ENSG00000172757homo_sapiensENSP0000030962981.927772.8916anolis_carolinensisENSACAP0000000858252.509746.7181
ENSG00000172757homo_sapiensENSP0000030962987.349477.1084neolamprologus_brichardiENSNBRP0000003058786.826376.6467
ENSG00000172757homo_sapiensENSP0000030962986.74780.7229naja_najaENSNNAP0000002434586.74780.7229
ENSG00000172757homo_sapiensENSP0000030962996.385595.1807podarcis_muralisENSPMRP0000002354296.969795.7576
ENSG00000172757homo_sapiensENSP0000030962987.951882.5301erpetoichthys_calabaricusENSECRP0000000459889.024483.5366
ENSG00000172757homo_sapiensENSP0000030962987.349474.6988kryptolebias_marmoratusENSKMAP0000000453785.798873.3728
ENSG00000172757homo_sapiensENSP0000030962980.120576.506salvator_merianaeENSSMRP0000002638854.508252.0492
ENSG00000172757homo_sapiensENSP0000030962986.144675.3012oryzias_javanicusENSOJAP0000002977785.628774.8503
ENSG00000172757homo_sapiensENSP0000030962986.74777.1084amphilophus_citrinellusENSACIP0000001314770.93663.0542
ENSG00000172757homo_sapiensENSP0000030962986.74775.3012dicentrarchus_labraxENSDLAP0000504779884.210573.0994
ENSG00000172757homo_sapiensENSP0000030962985.542272.8916amphiprion_perculaENSAPEP0000001260881.609269.5402
ENSG00000172757homo_sapiensENSP0000030962985.542274.0964oryzias_sinensisENSOSIP0000000639480.22669.4915
ENSG00000172757homo_sapiensENSP0000030962996.385589.759pelodiscus_sinensisENSPSIP0000000309096.385589.759
ENSG00000172757homo_sapiensENSP0000030962996.98891.5663gopherus_evgoodeiENSGEVP0000501314296.98891.5663
ENSG00000172757homo_sapiensENSP0000030962996.98891.5663chelonoidis_abingdoniiENSCABP0000002393496.98891.5663
ENSG00000172757homo_sapiensENSP0000030962987.349474.6988seriola_dumeriliENSSDUP0000002493786.826374.2515
ENSG00000172757homo_sapiensENSP0000030962986.74775.3012cottoperca_gobioENSCGOP0000002408486.227574.8503
ENSG00000172757homo_sapiensENSP0000030962987.349474.6988gasterosteus_aculeatusENSGACP0000002250186.826374.2515
ENSG00000172757homo_sapiensENSP0000030962982.530170.4819cynoglossus_semilaevisENSCSEP0000000730482.035970.0599
ENSG00000172757homo_sapiensENSP0000030962987.349475.9036poecilia_formosaENSPFOP0000000879286.826375.4491
ENSG00000172757homo_sapiensENSP0000030962987.349476.506myripristis_murdjanENSMMDP0000503880186.826376.0479
ENSG00000172757homo_sapiensENSP0000030962987.349475.3012sander_luciopercaENSSLUP0000003564786.826374.8503
ENSG00000172757homo_sapiensENSP0000030962985.542272.8916amphiprion_ocellarisENSAOCP0000002220282.558170.3488
ENSG00000172757homo_sapiensENSP0000030962996.98890.9639terrapene_carolina_triunguisENSTMTP0000002611796.98890.9639
ENSG00000172757homo_sapiensENSP0000030962987.349478.9157hucho_huchoENSHHUP0000004845586.826378.4431
ENSG00000172757homo_sapiensENSP0000030962986.74776.506hucho_huchoENSHHUP0000007302686.227576.0479
ENSG00000172757homo_sapiensENSP0000030962986.74777.7108hucho_huchoENSHHUP0000004113186.227577.2455
ENSG00000172757homo_sapiensENSP0000030962982.530175.3012hucho_huchoENSHHUP0000005043078.285771.4286
ENSG00000172757homo_sapiensENSP0000030962978.915767.4699betta_splendensENSBSLP0000001871287.333374.6667
ENSG00000172757homo_sapiensENSP0000030962986.144677.1084pygocentrus_nattereriENSPNAP0000003241386.666777.5758
ENSG00000172757homo_sapiensENSP0000030962987.349476.506anabas_testudineusENSATEP0000002160286.826376.0479
ENSG00000172757homo_sapiensENSP0000030962949.397629.5181ciona_savignyiENSCSAVP0000001840849.101829.3413
ENSG00000172757homo_sapiensENSP0000030962956.024135.5422saccharomyces_cerevisiaeYLL050C65.03541.2587
ENSG00000172757homo_sapiensENSP0000030962987.349475.3012seriola_lalandi_dorsalisENSSLDP0000002174686.826374.8503
ENSG00000172757homo_sapiensENSP0000030962969.277163.253labrus_bergyltaENSLBEP0000000942362.557.0652
ENSG00000172757homo_sapiensENSP0000030962987.349477.1084pundamilia_nyerereiENSPNYP0000001846986.826376.6467
ENSG00000172757homo_sapiensENSP0000030962987.951876.506mastacembelus_armatusENSMAMP0000003133387.425176.0479
ENSG00000172757homo_sapiensENSP0000030962987.349475.9036stegastes_partitusENSSPAP0000000893486.826375.4491
ENSG00000172757homo_sapiensENSP0000030962986.144676.506oncorhynchus_tshawytschaENSOTSP0000506060878.571469.7802
ENSG00000172757homo_sapiensENSP0000030962954.216950oncorhynchus_tshawytschaENSOTSP0000504355785.714379.0476
ENSG00000172757homo_sapiensENSP0000030962986.74777.1084oncorhynchus_tshawytschaENSOTSP0000502663273.469465.3061
ENSG00000172757homo_sapiensENSP0000030962986.144674.6988acanthochromis_polyacanthusENSAPOP0000000381183.139572.093
ENSG00000172757homo_sapiensENSP0000030962986.74774.6988nothobranchius_furzeriENSNFUP0001500249585.714373.8095
ENSG00000172757homo_sapiensENSP0000030962987.349475.3012cyprinodon_variegatusENSCVAP0000003013786.826374.8503
ENSG00000172757homo_sapiensENSP0000030962984.939876.506denticeps_clupeoidesENSDCDP0000001140685.454576.9697
ENSG00000172757homo_sapiensENSP0000030962982.530174.0964denticeps_clupeoidesENSDCDP0000001316684.049175.4601
ENSG00000172757homo_sapiensENSP0000030962987.349475.3012takifugu_rubripesENSTRUP0000003138886.826374.8503
ENSG00000172757homo_sapiensENSP0000030962986.144672.8916hippocampus_comesENSHCOP0000000258485.628772.4551
ENSG00000172757homo_sapiensENSP0000030962982.530173.494cyprinus_carpio_carpioENSCCRP0000001552775.690667.4033
ENSG00000172757homo_sapiensENSP0000030962983.734974.6988cyprinus_carpio_carpioENSCCRP0000015902078.531170.0565
ENSG00000172757homo_sapiensENSP0000030962986.74775.3012poecilia_latipinnaENSPLAP0000000710574.226864.433
ENSG00000172757homo_sapiensENSP0000030962984.337373.494sinocyclocheilus_grahamiENSSGRP0000005201384.848573.9394
ENSG00000172757homo_sapiensENSP0000030962987.349477.1084maylandia_zebraENSMZEP0000500689286.826376.6467
ENSG00000172757homo_sapiensENSP0000030962987.349475.9036tetraodon_nigroviridisENSTNIP0000001993286.826375.4491
ENSG00000172757homo_sapiensENSP0000030962985.542275.3012paramormyrops_kingsleyaeENSPKIP0000000970386.585476.2195
ENSG00000172757homo_sapiensENSP0000030962987.951875.9036paramormyrops_kingsleyaeENSPKIP0000002312156.589148.8372
ENSG00000172757homo_sapiensENSP0000030962987.951879.5181scleropages_formosusENSSFOP0001505098687.425179.0419
ENSG00000172757homo_sapiensENSP0000030962984.939871.0843scophthalmus_maximusENSSMAP000000272777562.766
ENSG00000172757homo_sapiensENSP0000030962986.144675.9036oryzias_melastigmaENSOMEP0000001620585.628775.4491

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000281involved_in mitotic cytokinesis1IBAHomo_sapiens(9606)Process
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005615located_in extracellular space1HDAHomo_sapiens(9606)Component
GO:0005634located_in nucleus1TASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005925located_in focal adhesion2HDA,IDAHomo_sapiens(9606)Component
GO:0007010involved_in cytoskeleton organization1IMPHomo_sapiens(9606)Process
GO:0007266involved_in Rho protein signal transduction1TASHomo_sapiens(9606)Process
GO:0009615involved_in response to virus1IEPHomo_sapiens(9606)Process
GO:0015629is_active_in actin cytoskeleton1IBAHomo_sapiens(9606)Component
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016363located_in nuclear matrix1IEAHomo_sapiens(9606)Component
GO:0022604involved_in regulation of cell morphogenesis1IMPHomo_sapiens(9606)Process
GO:0030027is_active_in lamellipodium2IBA,ISSHomo_sapiens(9606)Component
GO:0030036involved_in actin cytoskeleton organization1TASHomo_sapiens(9606)Process
GO:0030042involved_in actin filament depolymerization2IDA,NASHomo_sapiens(9606)Process
GO:0030043involved_in actin filament fragmentation1IBAHomo_sapiens(9606)Process
GO:0030426located_in growth cone1IEAHomo_sapiens(9606)Component
GO:0031258located_in lamellipodium membrane1IEAHomo_sapiens(9606)Component
GO:0031982located_in vesicle1HDAHomo_sapiens(9606)Component
GO:0032587located_in ruffle membrane1IEAHomo_sapiens(9606)Component
GO:0040019involved_in positive regulation of embryonic development1ISSHomo_sapiens(9606)Process
GO:0043066involved_in negative regulation of apoptotic process1TASHomo_sapiens(9606)Process
GO:0044794involved_in positive regulation by host of viral process1IMPHomo_sapiens(9606)Process
GO:0051014involved_in actin filament severing1IBAHomo_sapiens(9606)Process
GO:0051015enables actin filament binding3IBA,IDA,ISSHomo_sapiens(9606)Function
GO:0051293involved_in establishment of spindle localization1ISSHomo_sapiens(9606)Process
GO:0061001involved_in regulation of dendritic spine morphogenesis1IMPHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component

Expression