RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
diverse
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000171865 Gene ID
246243 Accession
18466
Symbol
RNASEH1
Alias
RNH1;H1RNA;PEOB2
Full Name
ribonuclease H1
Status
Confidence
Length
16904 bases
Strand
Minus strand
Position
2 : 3541430 - 3558333
RNA binding domain
RNase_H
Summary
This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000313350
RNase_H
PF00075 6.9e-44
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
32010626 The Interplay Between the DNA Damage Response, RNA Processing and Extracellular Vesicles.
Xiangbing Meng
2019-01-01
Frontiers in oncology
32782413 Advances in oligonucleotide drug delivery.
C Thomas Roberts
2020-10-01
Nature reviews. Drug discovery
36369963 Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway.
K Anna Dreismann
2023-01-01
Immunological reviews
28982376 Gene suppression approaches to neurodegeneration.
Rhia Ghosh
2017-10-05
Alzheimer's research & therapy
36573111 Hereditary Transthyretin Amyloidosis with Polyneuropathy: Monitoring and Management.
Valentina Vélez-Santamaría
2022-01-01
International journal of general medicine
30996261 R-ChIP for genome-wide mapping of R-loops by using catalytically inactive RNASEH1.
Jia-Yu Chen
2019-05-01
Nature protocols
31753913 Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.
Jin Jae Kim
2019-12-01
Genes & development
34412058 Antisense Oligonucleotide Therapy for Neurodevelopmental Disorders.
F Sophie Hill
2021-01-01
Developmental neuroscience
29104020 R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters.
Liang Chen
2017-11-16
Molecular cell
29315404 Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition.
Jongsu Choi
2018-02-28
Nucleic acids research
27415589 The notorious R.N.A. in the spotlight - drug or target for the treatment of disease.
Philipp Reautschnig
2017-05-04
RNA biology
22387027 R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters.
A Paul Ginno
2012-03-30
Molecular cell
27571227 Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions.
A Timothy Vickers
2016-01-01
PloS one
Name
Transcript ID
bp
Protein
Translation ID
RNASEH1-202
ENST00000436842
2120
43aa
ENSP00000404926
RNASEH1-201
ENST00000315212
5289
286aa
ENSP00000313350
RNASEH1-204
ENST00000464986
514
No protein
-
RNASEH1-203
ENST00000454734
749
43aa
ENSP00000411646
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000171865
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000171865 homo_sapiens ENSP00000313350 83.9161 82.8671 nomascus_leucogenys ENSNLEP00000018687 97.561 96.3415 ENSG00000171865 homo_sapiens ENSP00000313350 99.6504 99.6504 pan_paniscus ENSPPAP00000022028 99.6504 99.6504 ENSG00000171865 homo_sapiens ENSP00000313350 97.2028 96.8531 pongo_abelii ENSPPYP00000023502 97.2028 96.8531 ENSG00000171865 homo_sapiens ENSP00000313350 99.6504 99.6504 pan_troglodytes ENSPTRP00000019974 99.6504 99.6504 ENSG00000171865 homo_sapiens ENSP00000313350 98.6014 97.5524 gorilla_gorilla ENSGGOP00000028596 98.6014 97.5524 ENSG00000171865 homo_sapiens ENSP00000313350 78.3217 68.8811 ornithorhynchus_anatinus ENSOANP00000038939 46.281 40.7025 ENSG00000171865 homo_sapiens ENSP00000313350 77.2727 67.1329 sarcophilus_harrisii ENSSHAP00000038821 77.5439 67.3684 ENSG00000171865 homo_sapiens ENSP00000313350 35.3147 24.8252 sarcophilus_harrisii ENSSHAP00000041049 55.4945 39.011 ENSG00000171865 homo_sapiens ENSP00000313350 56.2937 46.5035 notamacropus_eugenii ENSMEUP00000003300 57.2954 47.331 ENSG00000171865 homo_sapiens ENSP00000313350 61.1888 57.3427 choloepus_hoffmanni ENSCHOP00000007559 86.2069 80.7882 ENSG00000171865 homo_sapiens ENSP00000313350 85.6643 79.021 dasypus_novemcinctus ENSDNOP00000012453 85.3659 78.7456 ENSG00000171865 homo_sapiens ENSP00000313350 83.2168 74.8252 echinops_telfairi ENSETEP00000010276 83.8028 75.3521 ENSG00000171865 homo_sapiens ENSP00000313350 95.1049 92.6573 callithrix_jacchus ENSCJAP00000048160 93.7931 91.3793 ENSG00000171865 homo_sapiens ENSP00000313350 97.2028 94.0559 cercocebus_atys ENSCATP00000004843 97.2028 94.0559 ENSG00000171865 homo_sapiens ENSP00000313350 86.7133 83.2168 cercocebus_atys ENSCATP00000005000 90.1818 86.5455 ENSG00000171865 homo_sapiens ENSP00000313350 86.7133 83.9161 macaca_fascicularis ENSMFAP00000053888 84.6416 81.9113 ENSG00000171865 homo_sapiens ENSP00000313350 96.5035 93.7063 macaca_mulatta ENSMMUP00000019005 96.5035 93.7063 ENSG00000171865 homo_sapiens ENSP00000313350 96.5035 93.3566 macaca_nemestrina ENSMNEP00000033927 96.5035 93.3566 ENSG00000171865 homo_sapiens ENSP00000313350 86.7133 82.8671 macaca_nemestrina ENSMNEP00000010543 89.5307 85.5596 ENSG00000171865 homo_sapiens ENSP00000313350 96.8531 93.3566 papio_anubis ENSPANP00000012808 96.8531 93.3566 ENSG00000171865 homo_sapiens ENSP00000313350 88.8112 84.965 mandrillus_leucophaeus ENSMLEP00000008926 91.6968 87.7256 ENSG00000171865 homo_sapiens ENSP00000313350 83.2168 80.7692 mandrillus_leucophaeus ENSMLEP00000030308 97.9424 95.0617 ENSG00000171865 homo_sapiens ENSP00000313350 82.8671 77.2727 tursiops_truncatus ENSTTRP00000001521 82.8671 77.2727 ENSG00000171865 homo_sapiens ENSP00000313350 88.4615 83.2168 vulpes_vulpes ENSVVUP00000011709 79.5597 74.8428 ENSG00000171865 homo_sapiens ENSP00000313350 85.6643 77.6224 mus_spretus MGP_SPRETEiJ_P0033504 85.9649 77.8947 ENSG00000171865 homo_sapiens ENSP00000313350 88.1119 82.5175 equus_asinus ENSEASP00005032519 86.0068 80.5461 ENSG00000171865 homo_sapiens ENSP00000313350 62.5874 55.2448 capra_hircus ENSCHIP00000025462 79.2035 69.9115 ENSG00000171865 homo_sapiens ENSP00000313350 84.6154 76.9231 capra_hircus ENSCHIP00000025542 84.9123 77.193 ENSG00000171865 homo_sapiens ENSP00000313350 85.6643 80.0699 loxodonta_africana ENSLAFP00000012637 85.3659 79.7909 ENSG00000171865 homo_sapiens ENSP00000313350 89.1608 81.8182 panthera_leo ENSPLOP00000002660 89.4737 82.1053 ENSG00000171865 homo_sapiens ENSP00000313350 82.5175 74.1259 ailuropoda_melanoleuca ENSAMEP00000033021 78.1457 70.1987 ENSG00000171865 homo_sapiens ENSP00000313350 83.9161 77.2727 bos_indicus_hybrid ENSBIXP00005026540 80.5369 74.1611 ENSG00000171865 homo_sapiens ENSP00000313350 87.0629 81.1189 oryctolagus_cuniculus ENSOCUP00000005300 87.0629 81.1189 ENSG00000171865 homo_sapiens ENSP00000313350 81.8182 75.8741 equus_caballus ENSECAP00000053253 73.3542 68.0251 ENSG00000171865 homo_sapiens ENSP00000313350 87.7622 82.5175 canis_lupus_familiaris ENSCAFP00845029733 88.0702 82.807 ENSG00000171865 homo_sapiens ENSP00000313350 89.1608 81.8182 panthera_pardus ENSPPRP00000025270 89.4737 82.1053 ENSG00000171865 homo_sapiens ENSP00000313350 77.972 70.979 marmota_marmota_marmota ENSMMMP00000026116 84.7909 77.1863 ENSG00000171865 homo_sapiens ENSP00000313350 77.6224 70.979 balaenoptera_musculus ENSBMSP00010019105 85.7143 78.3784 ENSG00000171865 homo_sapiens ENSP00000313350 84.965 77.972 cavia_porcellus ENSCPOP00000016813 82.6531 75.8503 ENSG00000171865 homo_sapiens ENSP00000313350 75.1748 65.035 felis_catus ENSFCAP00000058842 70.4918 60.9836 ENSG00000171865 homo_sapiens ENSP00000313350 56.6434 52.7972 ursus_americanus ENSUAMP00000023282 83.9378 78.2383 ENSG00000171865 homo_sapiens ENSP00000313350 78.3217 68.5315 monodelphis_domestica ENSMODP00000018108 78.3217 68.5315 ENSG00000171865 homo_sapiens ENSP00000313350 63.2867 52.4476 monodelphis_domestica ENSMODP00000039512 73.8775 61.2245 ENSG00000171865 homo_sapiens ENSP00000313350 83.9161 77.2727 bison_bison_bison ENSBBBP00000011865 85.7143 78.9286 ENSG00000171865 homo_sapiens ENSP00000313350 88.1119 82.1678 monodon_monoceros ENSMMNP00015010823 87.8049 81.8815 ENSG00000171865 homo_sapiens ENSP00000313350 83.5664 77.6224 sus_scrofa ENSSSCP00000027507 83.2753 77.3519 ENSG00000171865 homo_sapiens ENSP00000313350 89.8601 84.965 microcebus_murinus ENSMICP00000026802 89.547 84.669 ENSG00000171865 homo_sapiens ENSP00000313350 84.2657 78.3217 octodon_degus ENSODEP00000000260 83.391 77.5087 ENSG00000171865 homo_sapiens ENSP00000313350 74.4755 66.0839 jaculus_jaculus ENSJJAP00000004327 84.8606 75.2988 ENSG00000171865 homo_sapiens ENSP00000313350 81.4685 72.3776 jaculus_jaculus ENSJJAP00000020972 86.2963 76.6667 ENSG00000171865 homo_sapiens ENSP00000313350 77.6224 70.2797 jaculus_jaculus ENSJJAP00000019219 87.4016 79.1339 ENSG00000171865 homo_sapiens ENSP00000313350 83.9161 76.2238 ovis_aries_rambouillet ENSOARP00020003432 84.2105 76.4912 ENSG00000171865 homo_sapiens ENSP00000313350 68.5315 60.1399 ursus_maritimus ENSUMAP00000004930 65.3333 57.3333 ENSG00000171865 homo_sapiens ENSP00000313350 81.8182 72.7273 ochotona_princeps ENSOPRP00000004662 81.5331 72.4739 ENSG00000171865 homo_sapiens ENSP00000313350 88.1119 82.1678 delphinapterus_leucas ENSDLEP00000014113 87.8049 81.8815 ENSG00000171865 homo_sapiens ENSP00000313350 86.3636 79.3706 physeter_catodon ENSPCTP00005014650 86.0627 79.0941 ENSG00000171865 homo_sapiens ENSP00000313350 86.014 77.2727 mus_caroli MGP_CAROLIEiJ_P0032031 86.3158 77.5439 ENSG00000171865 homo_sapiens ENSP00000313350 86.014 77.2727 mus_musculus ENSMUSP00000020959 86.3158 77.5439 ENSG00000171865 homo_sapiens ENSP00000313350 85.6643 79.021 dipodomys_ordii ENSDORP00000000656 86.2676 79.5775 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 58.7413 mustela_putorius_furo ENSMPUP00000012884 88.3495 81.5534 ENSG00000171865 homo_sapiens ENSP00000313350 94.4056 92.6573 aotus_nancymaae ENSANAP00000012238 94.4056 92.6573 ENSG00000171865 homo_sapiens ENSP00000313350 93.007 91.2587 saimiri_boliviensis_boliviensis ENSSBOP00000017528 92.3611 90.625 ENSG00000171865 homo_sapiens ENSP00000313350 69.9301 63.986 vicugna_pacos ENSVPAP00000010788 69.9301 63.986 ENSG00000171865 homo_sapiens ENSP00000313350 96.1538 92.6573 chlorocebus_sabaeus ENSCSAP00000003230 96.1538 92.6573 ENSG00000171865 homo_sapiens ENSP00000313350 86.014 75.8741 mesocricetus_auratus ENSMAUP00000015535 86.3158 76.1404 ENSG00000171865 homo_sapiens ENSP00000313350 88.1119 82.5175 phocoena_sinus ENSPSNP00000031086 87.8049 82.23 ENSG00000171865 homo_sapiens ENSP00000313350 83.5664 74.1259 camelus_dromedarius ENSCDRP00005020875 60.2015 53.4005 ENSG00000171865 homo_sapiens ENSP00000313350 87.7622 82.1678 carlito_syrichta ENSTSYP00000011867 86.8512 81.3149 ENSG00000171865 homo_sapiens ENSP00000313350 77.2727 72.028 panthera_tigris_altaica ENSPTIP00000022121 77.8169 72.5352 ENSG00000171865 homo_sapiens ENSP00000313350 84.6154 76.5734 rattus_norvegicus ENSRNOP00000011819 84.9123 76.8421 ENSG00000171865 homo_sapiens ENSP00000313350 90.2098 84.965 prolemur_simus ENSPSMP00000008739 88.6598 83.5052 ENSG00000171865 homo_sapiens ENSP00000313350 85.6643 76.9231 microtus_ochrogaster ENSMOCP00000016690 85.0694 76.3889 ENSG00000171865 homo_sapiens ENSP00000313350 86.014 77.2727 peromyscus_maniculatus_bairdii ENSPEMP00000026309 85.7143 77.0035 ENSG00000171865 homo_sapiens ENSP00000313350 69.9301 61.8881 bos_mutus ENSBMUP00000028388 72.4638 64.1304 ENSG00000171865 homo_sapiens ENSP00000313350 85.6643 77.2727 mus_spicilegus ENSMSIP00000002164 85.9649 77.5439 ENSG00000171865 homo_sapiens ENSP00000313350 84.965 75.5245 cricetulus_griseus_chok1gshd ENSCGRP00001006606 85.2632 75.7895 ENSG00000171865 homo_sapiens ENSP00000313350 83.5664 75.5245 pteropus_vampyrus ENSPVAP00000001958 83.8596 75.7895 ENSG00000171865 homo_sapiens ENSP00000313350 78.3217 68.1818 vombatus_ursinus ENSVURP00010013094 78.3217 68.1818 ENSG00000171865 homo_sapiens ENSP00000313350 37.4126 27.6224 vombatus_ursinus ENSVURP00010012970 60.1124 44.382 ENSG00000171865 homo_sapiens ENSP00000313350 88.4615 78.6713 rhinolophus_ferrumequinum ENSRFEP00010016122 88.4615 78.6713 ENSG00000171865 homo_sapiens ENSP00000313350 82.5175 74.1259 neovison_vison ENSNVIP00000020367 80.5461 72.3549 ENSG00000171865 homo_sapiens ENSP00000313350 83.9161 77.2727 bos_taurus ENSBTAP00000063545 80.5369 74.1611 ENSG00000171865 homo_sapiens ENSP00000313350 84.2657 75.5245 heterocephalus_glaber_female ENSHGLP00000040294 78.2467 70.1299 ENSG00000171865 homo_sapiens ENSP00000313350 96.1538 92.6573 rhinopithecus_bieti ENSRBIP00000020465 95.1557 91.6955 ENSG00000171865 homo_sapiens ENSP00000313350 51.7483 50.6993 canis_lupus_dingo ENSCAFP00020006164 95.4839 93.5484 ENSG00000171865 homo_sapiens ENSP00000313350 86.7133 79.7203 sciurus_vulgaris ENSSVLP00005027494 86.7133 79.7203 ENSG00000171865 homo_sapiens ENSP00000313350 38.4615 25.5245 phascolarctos_cinereus ENSPCIP00000035202 51.6432 34.2723 ENSG00000171865 homo_sapiens ENSP00000313350 48.2517 41.2587 phascolarctos_cinereus ENSPCIP00000031422 70.0508 59.8985 ENSG00000171865 homo_sapiens ENSP00000313350 80.7692 74.4755 procavia_capensis ENSPCAP00000002344 80.4878 74.216 ENSG00000171865 homo_sapiens ENSP00000313350 85.3147 76.9231 nannospalax_galili ENSNGAP00000014743 80 72.1311 ENSG00000171865 homo_sapiens ENSP00000313350 84.2657 77.6224 bos_grunniens ENSBGRP00000021912 77.7419 71.6129 ENSG00000171865 homo_sapiens ENSP00000313350 86.014 79.021 chinchilla_lanigera ENSCLAP00000003408 86.6197 79.5775 ENSG00000171865 homo_sapiens ENSP00000313350 84.2657 77.2727 cervus_hanglu_yarkandensis ENSCHYP00000012341 84.5614 77.5439 ENSG00000171865 homo_sapiens ENSP00000313350 83.9161 77.6224 catagonus_wagneri ENSCWAP00000011713 83.6237 77.3519 ENSG00000171865 homo_sapiens ENSP00000313350 84.6154 77.972 ictidomys_tridecemlineatus ENSSTOP00000011448 86.4286 79.6429 ENSG00000171865 homo_sapiens ENSP00000313350 87.7622 83.5664 otolemur_garnettii ENSOGAP00000015386 87.4564 83.2753 ENSG00000171865 homo_sapiens ENSP00000313350 94.0559 91.6084 cebus_imitator ENSCCAP00000040444 93.4028 90.9722 ENSG00000171865 homo_sapiens ENSP00000313350 80.7692 72.7273 urocitellus_parryii ENSUPAP00010026496 58.3333 52.5253 ENSG00000171865 homo_sapiens ENSP00000313350 84.6154 76.9231 moschus_moschiferus ENSMMSP00000023880 84.9123 77.193 ENSG00000171865 homo_sapiens ENSP00000313350 96.1538 93.007 rhinopithecus_roxellana ENSRROP00000036603 95.1557 92.0415 ENSG00000171865 homo_sapiens ENSP00000313350 85.6643 76.9231 mus_pahari MGP_PahariEiJ_P0082149 85.9649 77.193 ENSG00000171865 homo_sapiens ENSP00000313350 82.8671 77.2727 propithecus_coquereli ENSPCOP00000015414 89.0977 83.0827 ENSG00000171865 homo_sapiens ENSP00000313350 51.7483 37.7622 caenorhabditis_elegans F59A6.6c.1 58.9641 43.0279 ENSG00000171865 homo_sapiens ENSP00000313350 47.2028 37.4126 drosophila_melanogaster FBpp0087959 40.5405 32.1321 ENSG00000171865 homo_sapiens ENSP00000313350 50 38.1119 ciona_intestinalis ENSCINP00000025561 48.6395 37.0748 ENSG00000171865 homo_sapiens ENSP00000313350 56.2937 41.958 petromyzon_marinus ENSPMAP00000009046 63.3858 47.2441 ENSG00000171865 homo_sapiens ENSP00000313350 58.042 47.2028 petromyzon_marinus ENSPMAP00000003094 57.4394 46.7128 ENSG00000171865 homo_sapiens ENSP00000313350 38.8112 30.4196 petromyzon_marinus ENSPMAP00000000561 70.7006 55.414 ENSG00000171865 homo_sapiens ENSP00000313350 57.3427 41.958 eptatretus_burgeri ENSEBUP00000009518 40.1961 29.4118 ENSG00000171865 homo_sapiens ENSP00000313350 57.3427 45.4545 eptatretus_burgeri ENSEBUP00000014110 55.7823 44.2177 ENSG00000171865 homo_sapiens ENSP00000313350 61.1888 50.3497 callorhinchus_milii ENSCMIP00000015011 64.1026 52.7473 ENSG00000171865 homo_sapiens ENSP00000313350 66.7832 54.5455 latimeria_chalumnae ENSLACP00000008022 61.6129 50.3226 ENSG00000171865 homo_sapiens ENSP00000313350 66.7832 54.1958 lepisosteus_oculatus ENSLOCP00000021280 68.705 55.7554 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 51.049 clupea_harengus ENSCHAP00000032952 58.9172 46.4968 ENSG00000171865 homo_sapiens ENSP00000313350 60.1399 49.3007 danio_rerio ENSDARP00000062440 62.3188 51.087 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 51.049 carassius_auratus ENSCARP00000058558 60.066 48.1848 ENSG00000171865 homo_sapiens ENSP00000313350 55.5944 45.1049 carassius_auratus ENSCARP00000012629 50.6369 41.0828 ENSG00000171865 homo_sapiens ENSP00000313350 56.2937 45.8042 astyanax_mexicanus ENSAMXP00000053791 62.1622 50.5792 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 52.4476 ictalurus_punctatus ENSIPUP00000034348 65.233 53.7634 ENSG00000171865 homo_sapiens ENSP00000313350 61.1888 49.3007 esox_lucius ENSELUP00000046029 56.4516 45.4839 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 50 electrophorus_electricus ENSEEEP00000019908 65.371 50.53 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 50.6993 oncorhynchus_kisutch ENSOKIP00005077391 62.543 49.8282 ENSG00000171865 homo_sapiens ENSP00000313350 59.7902 47.5524 oncorhynchus_kisutch ENSOKIP00005074202 58.7629 46.7354 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 50.3497 oncorhynchus_mykiss ENSOMYP00000129734 55.6575 44.0367 ENSG00000171865 homo_sapiens ENSP00000313350 61.8881 50.3497 oncorhynchus_mykiss ENSOMYP00000022379 63.2143 51.4286 ENSG00000171865 homo_sapiens ENSP00000313350 58.042 45.8042 salmo_salar ENSSSAP00000035169 56.6553 44.7099 ENSG00000171865 homo_sapiens ENSP00000313350 65.035 52.0979 salmo_salar ENSSSAP00000106065 54.0698 43.314 ENSG00000171865 homo_sapiens ENSP00000313350 66.0839 53.1469 salmo_trutta ENSSTUP00000000227 63.2107 50.8361 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 50.6993 salmo_trutta ENSSTUP00000112697 62.543 49.8282 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 49.6503 gadus_morhua ENSGMOP00000014777 59.2834 46.2541 ENSG00000171865 homo_sapiens ENSP00000313350 40.5594 31.4685 fundulus_heteroclitus ENSFHEP00000017812 53.4562 41.4747 ENSG00000171865 homo_sapiens ENSP00000313350 62.9371 52.0979 poecilia_reticulata ENSPREP00000018030 59.8007 49.5017 ENSG00000171865 homo_sapiens ENSP00000313350 61.8881 50.3497 xiphophorus_maculatus ENSXMAP00000002361 60 48.8136 ENSG00000171865 homo_sapiens ENSP00000313350 60.1399 48.951 oryzias_latipes ENSORLP00000022700 62.3188 50.7246 ENSG00000171865 homo_sapiens ENSP00000313350 62.2378 49.3007 cyclopterus_lumpus ENSCLMP00005024037 58.9404 46.6887 ENSG00000171865 homo_sapiens ENSP00000313350 62.9371 50 oreochromis_niloticus ENSONIP00000023538 64.7482 51.4389 ENSG00000171865 homo_sapiens ENSP00000313350 65.035 52.0979 haplochromis_burtoni ENSHBUP00000003423 60.1942 48.2201 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 52.0979 astatotilapia_calliptera ENSACLP00000009862 59.8706 48.2201 ENSG00000171865 homo_sapiens ENSP00000313350 63.986 49.3007 sparus_aurata ENSSAUP00010045571 60.1974 46.3816 ENSG00000171865 homo_sapiens ENSP00000313350 62.9371 51.049 lates_calcarifer ENSLCAP00010024135 59.6026 48.3444 ENSG00000171865 homo_sapiens ENSP00000313350 63.986 53.1469 xenopus_tropicalis ENSXETP00000002605 60.596 50.3311 ENSG00000171865 homo_sapiens ENSP00000313350 66.0839 57.3427 chrysemys_picta_bellii ENSCPBP00000030739 46.4373 40.2948 ENSG00000171865 homo_sapiens ENSP00000313350 65.3846 55.5944 sphenodon_punctatus ENSSPUP00000008546 64.7059 55.0173 ENSG00000171865 homo_sapiens ENSP00000313350 67.8322 56.993 crocodylus_porosus ENSCPRP00005011995 52.5745 44.1734 ENSG00000171865 homo_sapiens ENSP00000313350 67.4825 56.993 laticauda_laticaudata ENSLLTP00000022484 65.4237 55.2542 ENSG00000171865 homo_sapiens ENSP00000313350 68.1818 56.993 notechis_scutatus ENSNSUP00000010079 66.1017 55.2542 ENSG00000171865 homo_sapiens ENSP00000313350 67.4825 55.9441 pseudonaja_textilis ENSPTXP00000015829 65.4237 54.2373 ENSG00000171865 homo_sapiens ENSP00000313350 69.2308 60.4895 anas_platyrhynchos_platyrhynchos ENSAPLP00000001433 64.4951 56.3518 ENSG00000171865 homo_sapiens ENSP00000313350 70.6294 58.3916 gallus_gallus ENSGALP00010003063 66.0131 54.5752 ENSG00000171865 homo_sapiens ENSP00000313350 55.9441 47.5524 meleagris_gallopavo ENSMGAP00000024045 53.1561 45.1827 ENSG00000171865 homo_sapiens ENSP00000313350 65.7343 55.9441 serinus_canaria ENSSCAP00000016620 63.0872 53.6913 ENSG00000171865 homo_sapiens ENSP00000313350 67.1329 55.5944 parus_major ENSPMJP00000013719 65.0847 53.8983 ENSG00000171865 homo_sapiens ENSP00000313350 60.8392 51.049 anolis_carolinensis ENSACAP00000016603 49.7143 41.7143 ENSG00000171865 homo_sapiens ENSP00000313350 64.3357 52.4476 neolamprologus_brichardi ENSNBRP00000011192 59.5469 48.5437 ENSG00000171865 homo_sapiens ENSP00000313350 66.7832 56.2937 naja_naja ENSNNAP00000016123 64.7458 54.5763 ENSG00000171865 homo_sapiens ENSP00000313350 66.0839 55.2448 podarcis_muralis ENSPMRP00000017415 53.8462 45.0142 ENSG00000171865 homo_sapiens ENSP00000313350 53.1469 46.8531 geospiza_fortis ENSGFOP00000006659 62.8099 55.3719 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 52.0979 taeniopygia_guttata ENSTGUP00000037571 49.4652 39.8396 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 52.0979 erpetoichthys_calabaricus ENSECRP00000015416 62.2896 50.1684 ENSG00000171865 homo_sapiens ENSP00000313350 63.2867 50.3497 kryptolebias_marmoratus ENSKMAP00000001727 61.9863 49.3151 ENSG00000171865 homo_sapiens ENSP00000313350 63.2867 51.7483 salvator_merianae ENSSMRP00000008152 66.0584 54.0146 ENSG00000171865 homo_sapiens ENSP00000313350 58.3916 47.2028 oryzias_javanicus ENSOJAP00000041151 54.3974 43.9739 ENSG00000171865 homo_sapiens ENSP00000313350 63.986 52.0979 amphilophus_citrinellus ENSACIP00000018844 61.4094 50 ENSG00000171865 homo_sapiens ENSP00000313350 62.5874 49.6503 dicentrarchus_labrax ENSDLAP00005081561 61.3014 48.6301 ENSG00000171865 homo_sapiens ENSP00000313350 66.7832 53.8462 amphiprion_percula ENSAPEP00000019725 63.6667 51.3333 ENSG00000171865 homo_sapiens ENSP00000313350 67.1329 58.042 pelodiscus_sinensis ENSPSIP00000003050 64.6465 55.8923 ENSG00000171865 homo_sapiens ENSP00000313350 67.8322 58.042 gopherus_evgoodei ENSGEVP00005012823 71.3235 61.0294 ENSG00000171865 homo_sapiens ENSP00000313350 68.5315 59.0909 chelonoidis_abingdonii ENSCABP00000028935 72.0588 62.1324 ENSG00000171865 homo_sapiens ENSP00000313350 62.9371 50 seriola_dumerili ENSSDUP00000011243 58.8235 46.732 ENSG00000171865 homo_sapiens ENSP00000313350 59.7902 46.8531 cottoperca_gobio ENSCGOP00000044173 49.7093 38.9535 ENSG00000171865 homo_sapiens ENSP00000313350 51.7483 45.4545 struthio_camelus_australis ENSSCUP00000004939 74.3719 65.3266 ENSG00000171865 homo_sapiens ENSP00000313350 68.8811 60.1399 anser_brachyrhynchus ENSABRP00000010089 60.6154 52.9231 ENSG00000171865 homo_sapiens ENSP00000313350 62.9371 50.6993 gasterosteus_aculeatus ENSGACP00000015792 60.4027 48.6577 ENSG00000171865 homo_sapiens ENSP00000313350 62.9371 50 cynoglossus_semilaevis ENSCSEP00000008997 56.962 45.2532 ENSG00000171865 homo_sapiens ENSP00000313350 59.0909 47.9021 poecilia_formosa ENSPFOP00000002783 57.483 46.5986 ENSG00000171865 homo_sapiens ENSP00000313350 63.986 51.7483 myripristis_murdjan ENSMMDP00005021943 58.0952 46.9841 ENSG00000171865 homo_sapiens ENSP00000313350 61.1888 48.6014 sander_lucioperca ENSSLUP00000008062 57.0033 45.2769 ENSG00000171865 homo_sapiens ENSP00000313350 67.4825 57.6923 strigops_habroptila ENSSHBP00005006865 66.323 56.701 ENSG00000171865 homo_sapiens ENSP00000313350 66.0839 53.4965 amphiprion_ocellaris ENSAOCP00000026776 63 51 ENSG00000171865 homo_sapiens ENSP00000313350 68.5315 58.3916 terrapene_carolina_triunguis ENSTMTP00000001955 72.0588 61.3971 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 52.0979 hucho_hucho ENSHHUP00000045514 62.0805 50 ENSG00000171865 homo_sapiens ENSP00000313350 62.9371 49.6503 hucho_hucho ENSHHUP00000067940 63.6042 50.1767 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 51.7483 betta_splendens ENSBSLP00000012412 62.0805 49.6644 ENSG00000171865 homo_sapiens ENSP00000313350 64.3357 52.0979 pygocentrus_nattereri ENSPNAP00000016211 64.7887 52.4648 ENSG00000171865 homo_sapiens ENSP00000313350 65.7343 51.3986 anabas_testudineus ENSATEP00000000794 62.0462 48.5149 ENSG00000171865 homo_sapiens ENSP00000313350 40.2098 30.7692 ciona_savignyi ENSCSAVP00000000011 49.7836 38.0952 ENSG00000171865 homo_sapiens ENSP00000313350 45.8042 31.4685 saccharomyces_cerevisiae YMR234W 37.6437 25.8621 ENSG00000171865 homo_sapiens ENSP00000313350 61.1888 49.3007 seriola_lalandi_dorsalis ENSSLDP00000000526 54.5171 43.9252 ENSG00000171865 homo_sapiens ENSP00000313350 62.5874 47.5524 labrus_bergylta ENSLBEP00000006004 61.9377 47.0588 ENSG00000171865 homo_sapiens ENSP00000313350 64.3357 51.3986 pundamilia_nyererei ENSPNYP00000001607 59.5469 47.5728 ENSG00000171865 homo_sapiens ENSP00000313350 65.7343 53.8462 mastacembelus_armatus ENSMAMP00000029277 61.6393 50.4918 ENSG00000171865 homo_sapiens ENSP00000313350 66.0839 53.8462 stegastes_partitus ENSSPAP00000012312 62.5828 50.9934 ENSG00000171865 homo_sapiens ENSP00000313350 64.3357 52.0979 oncorhynchus_tshawytscha ENSOTSP00005019482 61.1296 49.5017 ENSG00000171865 homo_sapiens ENSP00000313350 63.2867 50.6993 oncorhynchus_tshawytscha ENSOTSP00005000956 62.1993 49.8282 ENSG00000171865 homo_sapiens ENSP00000313350 63.2867 50.6993 oncorhynchus_tshawytscha ENSOTSP00005061474 62.1993 49.8282 ENSG00000171865 homo_sapiens ENSP00000313350 65.035 52.4476 acanthochromis_polyacanthus ENSAPOP00000029135 62 50 ENSG00000171865 homo_sapiens ENSP00000313350 67.8322 57.3427 aquila_chrysaetos_chrysaetos ENSACCP00020007034 66.2116 55.9727 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 50.3497 nothobranchius_furzeri ENSNFUP00015028141 59.2949 46.1538 ENSG00000171865 homo_sapiens ENSP00000313350 62.5874 50.3497 cyprinodon_variegatus ENSCVAP00000015846 59.2715 47.6821 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 49.3007 denticeps_clupeoides ENSDCDP00000030922 61.9048 47.9592 ENSG00000171865 homo_sapiens ENSP00000313350 64.3357 51.049 larimichthys_crocea ENSLCRP00005057503 56.4417 44.7853 ENSG00000171865 homo_sapiens ENSP00000313350 66.0839 51.3986 takifugu_rubripes ENSTRUP00000047942 63 49 ENSG00000171865 homo_sapiens ENSP00000313350 68.1818 57.6923 ficedula_albicollis ENSFALP00000033768 65.4362 55.3691 ENSG00000171865 homo_sapiens ENSP00000313350 65.035 51.049 hippocampus_comes ENSHCOP00000009827 61.1842 48.0263 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 50.3497 cyprinus_carpio_carpio ENSCCRP00000026600 62.116 49.1468 ENSG00000171865 homo_sapiens ENSP00000313350 64.3357 51.049 cyprinus_carpio_carpio ENSCCRP00000134305 53.9589 42.8153 ENSG00000171865 homo_sapiens ENSP00000313350 69.5804 58.7413 coturnix_japonica ENSCJPP00005009798 67.9181 57.3379 ENSG00000171865 homo_sapiens ENSP00000313350 36.3636 26.5734 poecilia_latipinna ENSPLAP00000011779 57.4586 41.9889 ENSG00000171865 homo_sapiens ENSP00000313350 46.1538 38.4615 poecilia_latipinna ENSPLAP00000030353 53.8776 44.898 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 50.3497 sinocyclocheilus_grahami ENSSGRP00000055259 60.066 47.5248 ENSG00000171865 homo_sapiens ENSP00000313350 64.3357 50.3497 sinocyclocheilus_grahami ENSSGRP00000080246 61.9529 48.4848 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 52.0979 maylandia_zebra ENSMZEP00005017329 59.8706 48.2201 ENSG00000171865 homo_sapiens ENSP00000313350 62.5874 52.0979 tetraodon_nigroviridis ENSTNIP00000013633 64.8551 53.9855 ENSG00000171865 homo_sapiens ENSP00000313350 61.5385 46.8531 paramormyrops_kingsleyae ENSPKIP00000017106 65.6716 50 ENSG00000171865 homo_sapiens ENSP00000313350 63.6364 52.0979 scleropages_formosus ENSSFOP00015004190 60.066 49.1749 ENSG00000171865 homo_sapiens ENSP00000313350 64.6853 52.7972 leptobrachium_leishanense ENSLLEP00000038816 58.3596 47.6341 ENSG00000171865 homo_sapiens ENSP00000313350 65.035 51.7483 scophthalmus_maximus ENSSMAP00000053649 60 47.7419 ENSG00000171865 homo_sapiens ENSP00000313350 54.8951 44.7552 oryzias_melastigma ENSOMEP00000003783 59.9237 48.855
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000287 enables magnesium ion binding 1 IEA Homo_sapiens(9606) Function GO:0003676 enables nucleic acid binding 1 TAS Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 TAS Homo_sapiens(9606) Function GO:0004523 enables RNA-DNA hybrid ribonuclease activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0004540 enables RNA nuclease activity 1 TAS Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005737 located_in cytoplasm 1 IEA Homo_sapiens(9606) Component GO:0006401 involved_in RNA catabolic process 1 TAS Homo_sapiens(9606) Process GO:0043137 involved_in DNA replication, removal of RNA primer 1 IBA Homo_sapiens(9606) Process
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