RBP Type
Non-canonical_RBPs
Diseases
Flaviviruses SARS-COV-2 Dengue Zika
Drug
N.A.
Main interacting RNAs
rRNA
Moonlighting functions
TF
Localizations
Stress granule or P-body
BulkPerturb-seq
Ensembl ID ENSG00000170515 Gene ID
5036 Accession
8550
Symbol
PA2G4
Alias
EBP1;HG4-1;ITAF45;p38-2G4
Full Name
proliferation-associated 2G4
Status
Confidence
Length
9374 bases
Strand
Plus strand
Position
12 : 56104537 - 56113910
RNA binding domain
N.A.
Summary
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
28673244 A comprehensive genomic pan-cancer classification using The Cancer Genome Atlas gene expression data.
Yuanyuan Li
2017-07-03
BMC genomics
36606322 LINC00173 facilitates tumor progression by stimulating RAB1B-mediated PA2G4 and SDF4 secretion in nasopharyngeal carcinoma.
Shi-Wei He
2023-03-01
Molecular oncology
30023604 Indolizine-Based Scaffolds as Efficient and Versatile Tools: Application to the Synthesis of Biotin-Tagged Antiangiogenic Drugs.
Marie Arvin-Berod
2017-12-31
ACS omega
19642986 Proteomic profiling of glucocorticoid-exposed myogenic cells: Time series assessment of protein translocation and transcription of inactive mRNAs.
M K Erica Reeves
2009-07-30
Proteome science
33158116 The Role of Circular RNAs in Pancreatic Ductal Adenocarcinoma and Biliary-Tract Cancers.
Christopher Limb
2020-11-04
Cancers
35526051 PA2G4 promotes the metastasis of hepatocellular carcinoma by stabilizing FYN mRNA in a YTHDF2-dependent manner.
Sheng Sun
2022-05-07
Cell & bioscience
26150805 Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus.
Dylan Flather
2015-01-01
Frontiers in microbiology
18672925 Using proteomic approach to identify tumor-associated antigens as markers in hepatocellular carcinoma.
Sun Kok Looi
2008-09-01
Journal of proteome research
27940157 Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development.
M Karen Neilson
2017-01-15
Developmental biology
30799147 System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Manuel Garcia-Moreno
2019-04-04
Molecular cell
24421916 LmaPA2G4, a homolog of human Ebp1, is an essential gene and inhibits cell proliferation in L. major.
Brianna Norris-Mullins
2014-01-01
PLoS neglected tropical diseases
34257558 Identification of Biomarkers Related to Immune Cell Infiltration in Hepatocellular Carcinoma Using Gene Co-Expression Network.
Wanbang Zhou
2021-01-01
Pathology oncology research : POR
32179766 In-depth proteome analysis of more than 12,500 proteins in buffalo mammary epithelial cell line identifies protein signatures for active proliferation and lactation.
Shalini Jaswal
2020-03-16
Scientific reports
27457222 Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells.
P Stephen Smith
2016-07-26
Scientific reports
Name
Transcript ID
bp
Protein
Translation ID
PA2G4-206
ENST00000552766
1085
284aa
ENSP00000448557
PA2G4-201
ENST00000303305
2386
394aa
ENSP00000302886
PA2G4-207
ENST00000553057
687
187aa
ENSP00000447615
PA2G4-203
ENST00000551061
694
64aa
ENSP00000447389
PA2G4-202
ENST00000550166
520
No protein
-
PA2G4-205
ENST00000552528
289
No protein
-
PA2G4-204
ENST00000552266
779
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
87266 Alzheimer Disease 7E-8 26830138 87268 Age of Onset 7E-8 26830138
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000170515 homo_sapiens ENSP00000296411 23.5751 11.399 homo_sapiens ENSP00000302886 23.0964 11.1675 ENSG00000170515 homo_sapiens ENSP00000421566 16.6667 7.20721 homo_sapiens ENSP00000302886 28.1726 12.1827 ENSG00000170515 homo_sapiens ENSP00000360147 16.6172 7.8635 homo_sapiens ENSP00000302886 28.4264 13.4518 ENSG00000170515 homo_sapiens ENSP00000315152 26.5672 13.7313 homo_sapiens ENSP00000302886 22.5888 11.6751 ENSG00000170515 homo_sapiens ENSP00000349658 18.3432 8.87574 homo_sapiens ENSP00000302886 23.6041 11.4213 ENSG00000170515 homo_sapiens ENSP00000244137 22.7181 11.5619 homo_sapiens ENSP00000302886 28.4264 14.467 ENSG00000170515 homo_sapiens ENSP00000325312 32.8452 18.41 homo_sapiens ENSP00000302886 39.8477 22.335
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.4924 nomascus_leucogenys ENSNLEP00000021302 100 99.7455 ENSG00000170515 homo_sapiens ENSP00000302886 100 100 pan_paniscus ENSPPAP00000024545 100 100 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 99.4924 pongo_abelii ENSPPYP00000039875 99.7455 99.7455 ENSG00000170515 homo_sapiens ENSP00000302886 100 100 pongo_abelii ENSPPYP00000023481 100 100 ENSG00000170515 homo_sapiens ENSP00000302886 100 100 pan_troglodytes ENSPTRP00000073565 100 100 ENSG00000170515 homo_sapiens ENSP00000302886 100 100 gorilla_gorilla ENSGGOP00000036333 100 100 ENSG00000170515 homo_sapiens ENSP00000302886 97.9695 94.1624 ornithorhynchus_anatinus ENSOANP00000000970 97.9695 94.1624 ENSG00000170515 homo_sapiens ENSP00000302886 97.9695 95.6853 sarcophilus_harrisii ENSSHAP00000006602 97.9695 95.6853 ENSG00000170515 homo_sapiens ENSP00000302886 59.8985 57.868 notamacropus_eugenii ENSMEUP00000014522 59.8985 57.868 ENSG00000170515 homo_sapiens ENSP00000302886 84.7716 83.5025 choloepus_hoffmanni ENSCHOP00000006367 92.7778 91.3889 ENSG00000170515 homo_sapiens ENSP00000302886 80.4569 79.9492 dasypus_novemcinctus ENSDNOP00000000778 95.4819 94.8795 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 90.8629 erinaceus_europaeus ENSEEUP00000012902 92.0918 91.3265 ENSG00000170515 homo_sapiens ENSP00000302886 29.9492 29.6954 echinops_telfairi ENSETEP00000002069 56.7308 56.25 ENSG00000170515 homo_sapiens ENSP00000302886 100 100 callithrix_jacchus ENSCJAP00000021897 100 100 ENSG00000170515 homo_sapiens ENSP00000302886 54.5685 51.269 cercocebus_atys ENSCATP00000019451 84.3137 79.2157 ENSG00000170515 homo_sapiens ENSP00000302886 53.5533 49.4924 cercocebus_atys ENSCATP00000037358 85.7724 79.2683 ENSG00000170515 homo_sapiens ENSP00000302886 38.5787 36.0406 cercocebus_atys ENSCATP00000003044 80.8511 75.5319 ENSG00000170515 homo_sapiens ENSP00000302886 34.264 31.9797 cercocebus_atys ENSCATP00000040443 88.8158 82.8947 ENSG00000170515 homo_sapiens ENSP00000302886 82.2335 80.203 cercocebus_atys ENSCATP00000028870 86.4 84.2667 ENSG00000170515 homo_sapiens ENSP00000302886 59.1371 56.3452 macaca_fascicularis ENSMFAP00000014245 84.4203 80.4348 ENSG00000170515 homo_sapiens ENSP00000302886 81.9797 79.4416 macaca_nemestrina ENSMNEP00000009883 90.4762 87.6751 ENSG00000170515 homo_sapiens ENSP00000302886 81.9797 77.665 macaca_nemestrina ENSMNEP00000004969 89.7222 85 ENSG00000170515 homo_sapiens ENSP00000302886 52.2843 49.7462 macaca_nemestrina ENSMNEP00000030248 88.7931 84.4828 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 papio_anubis ENSPANP00000009768 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 77.665 73.8579 mandrillus_leucophaeus ENSMLEP00000036188 91.0714 86.6071 ENSG00000170515 homo_sapiens ENSP00000302886 80.9645 77.665 mandrillus_leucophaeus ENSMLEP00000027197 83.2898 79.8956 ENSG00000170515 homo_sapiens ENSP00000302886 71.5736 64.9746 mandrillus_leucophaeus ENSMLEP00000014334 75.2 68.2667 ENSG00000170515 homo_sapiens ENSP00000302886 81.9797 77.665 mandrillus_leucophaeus ENSMLEP00000008683 89.9721 85.2368 ENSG00000170515 homo_sapiens ENSP00000302886 97.4619 97.4619 tursiops_truncatus ENSTTRP00000015558 98.7147 98.7147 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 vulpes_vulpes ENSVVUP00000030152 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 99.2386 mus_spretus MGP_SPRETEiJ_P0026465 99.4924 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.2386 equus_asinus ENSEASP00005004648 99.7462 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 88.0711 87.5635 capra_hircus ENSCHIP00000013635 95.0685 94.5205 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.4924 loxodonta_africana ENSLAFP00000026306 99.7462 99.4924 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 panthera_leo ENSPLOP00000011506 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 ailuropoda_melanoleuca ENSAMEP00000003607 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 bos_indicus_hybrid ENSBIXP00005010480 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.4924 oryctolagus_cuniculus ENSOCUP00000014901 99.7462 99.4924 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.2386 equus_caballus ENSECAP00000005241 99.7462 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 canis_lupus_familiaris ENSCAFP00845008705 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 panthera_pardus ENSPPRP00000002628 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 99.2386 marmota_marmota_marmota ENSMMMP00000015756 99.4924 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 99.2386 balaenoptera_musculus ENSBMSP00010010084 99.2386 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 98.731 cavia_porcellus ENSCPOP00000013394 99.2386 98.731 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 felis_catus ENSFCAP00000013784 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 ursus_americanus ENSUAMP00000013469 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 98.2234 95.1777 monodelphis_domestica ENSMODP00000002440 98.2234 95.1777 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 bison_bison_bison ENSBBBP00000005195 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 99.2386 monodon_monoceros ENSMMNP00015026000 99.2386 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 61.4213 58.1218 sus_scrofa ENSSSCP00000041728 83.1615 78.6942 ENSG00000170515 homo_sapiens ENSP00000302886 92.8934 90.6091 microcebus_murinus ENSMICP00000013104 95.3125 92.9688 ENSG00000170515 homo_sapiens ENSP00000302886 70.5584 65.4822 octodon_degus ENSODEP00000005491 84.7561 78.6585 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 jaculus_jaculus ENSJJAP00000025014 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 90.6091 jaculus_jaculus ENSJJAP00000011741 94.7507 93.7008 ENSG00000170515 homo_sapiens ENSP00000302886 80.4569 75.3807 jaculus_jaculus ENSJJAP00000010976 90.8309 85.1003 ENSG00000170515 homo_sapiens ENSP00000302886 77.9188 76.3959 jaculus_jaculus ENSJJAP00000018002 94.1718 92.3313 ENSG00000170515 homo_sapiens ENSP00000302886 63.4518 63.4518 ovis_aries_rambouillet ENSOARP00020007388 94.3396 94.3396 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 ursus_maritimus ENSUMAP00000022974 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 98.9848 ochotona_princeps ENSOPRP00000005307 99.4924 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 99.2386 delphinapterus_leucas ENSDLEP00000008540 99.2386 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 99.2386 physeter_catodon ENSPCTP00005023991 99.2386 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 98.9848 mus_caroli MGP_CAROLIEiJ_P0025176 99.4924 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 98.9848 mus_musculus ENSMUSP00000114434 99.2386 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 94.9239 94.6701 dipodomys_ordii ENSDORP00000001014 99.2042 98.939 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 mustela_putorius_furo ENSMPUP00000001230 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 84.264 82.2335 mustela_putorius_furo ENSMPUP00000000882 94.5869 92.3077 ENSG00000170515 homo_sapiens ENSP00000302886 100 100 aotus_nancymaae ENSANAP00000038896 100 100 ENSG00000170515 homo_sapiens ENSP00000302886 70.0508 64.9746 saimiri_boliviensis_boliviensis ENSSBOP00000038352 82.1429 76.1905 ENSG00000170515 homo_sapiens ENSP00000302886 100 99.7462 saimiri_boliviensis_boliviensis ENSSBOP00000008461 100 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 51.5228 48.9848 vicugna_pacos ENSVPAP00000007776 98.0676 93.2367 ENSG00000170515 homo_sapiens ENSP00000302886 67.0051 66.7513 vicugna_pacos ENSVPAP00000008858 82.7586 82.4451 ENSG00000170515 homo_sapiens ENSP00000302886 85.0254 82.2335 chlorocebus_sabaeus ENSCSAP00000001551 84.596 81.8182 ENSG00000170515 homo_sapiens ENSP00000302886 76.3959 76.1421 tupaia_belangeri ENSTBEP00000000182 84.3137 84.0336 ENSG00000170515 homo_sapiens ENSP00000302886 53.2995 53.2995 mesocricetus_auratus ENSMAUP00000011157 100 100 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 99.2386 phocoena_sinus ENSPSNP00000013327 99.2386 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 83.7563 80.9645 camelus_dromedarius ENSCDRP00005007366 96.7742 93.5484 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 99.2386 camelus_dromedarius ENSCDRP00005007718 99.4924 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 74.6193 70.5584 carlito_syrichta ENSTSYP00000024314 74.6193 70.5584 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 panthera_tigris_altaica ENSPTIP00000001542 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 63.198 57.1066 rattus_norvegicus ENSRNOP00000034774 75 67.7711 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 98.9848 prolemur_simus ENSPSMP00000035438 99.7462 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 98.731 microtus_ochrogaster ENSMOCP00000002550 99.7462 98.731 ENSG00000170515 homo_sapiens ENSP00000302886 89.8477 89.3401 sorex_araneus ENSSARP00000006521 90.3061 89.7959 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 98.9848 peromyscus_maniculatus_bairdii ENSPEMP00000013264 99.4924 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 bos_mutus ENSBMUP00000022627 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 99.2386 mus_spicilegus ENSMSIP00000000874 99.4924 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 98.9848 cricetulus_griseus_chok1gshd ENSCGRP00001014324 99.7462 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 82.2335 81.4721 pteropus_vampyrus ENSPVAP00000007139 84.8168 84.0314 ENSG00000170515 homo_sapiens ENSP00000302886 51.7766 46.7005 myotis_lucifugus ENSMLUP00000019258 78.4615 70.7692 ENSG00000170515 homo_sapiens ENSP00000302886 97.9695 95.4315 vombatus_ursinus ENSVURP00010031006 97.9695 95.4315 ENSG00000170515 homo_sapiens ENSP00000302886 61.9289 58.6294 rhinolophus_ferrumequinum ENSRFEP00010031443 84.4291 79.9308 ENSG00000170515 homo_sapiens ENSP00000302886 58.1218 57.868 neovison_vison ENSNVIP00000028983 39.7569 39.5833 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 bos_taurus ENSBTAP00000013796 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 79.6954 77.665 heterocephalus_glaber_female ENSHGLP00000002292 87.9552 85.7143 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 rhinopithecus_bieti ENSRBIP00000016211 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 95.1777 95.1777 canis_lupus_dingo ENSCAFP00020033514 99.2064 99.2064 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 99.2386 sciurus_vulgaris ENSSVLP00005003792 99.4924 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 97.9695 95.6853 phascolarctos_cinereus ENSPCIP00000008464 97.9695 95.6853 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 99.4924 procavia_capensis ENSPCAP00000005169 99.4924 99.4924 ENSG00000170515 homo_sapiens ENSP00000302886 51.0152 47.7157 nannospalax_galili ENSNGAP00000009451 87.013 81.3853 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 bos_grunniens ENSBGRP00000001866 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 98.4772 chinchilla_lanigera ENSCLAP00000012821 99.2386 98.4772 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 98.9848 cervus_hanglu_yarkandensis ENSCHYP00000006480 99.4924 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 56.8528 56.0914 cervus_hanglu_yarkandensis ENSCHYP00000031561 98.6784 97.3568 ENSG00000170515 homo_sapiens ENSP00000302886 71.066 67.0051 catagonus_wagneri ENSCWAP00000005687 87.7743 82.7586 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 98.9848 ictidomys_tridecemlineatus ENSSTOP00000006920 99.2386 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.2386 otolemur_garnettii ENSOGAP00000001343 98.4962 97.995 ENSG00000170515 homo_sapiens ENSP00000302886 70.8122 65.2284 cebus_imitator ENSCCAP00000034142 85.061 78.3537 ENSG00000170515 homo_sapiens ENSP00000302886 99.2386 98.9848 urocitellus_parryii ENSUPAP00010019345 99.2386 98.9848 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.7462 moschus_moschiferus ENSMMSP00000019275 99.7462 99.7462 ENSG00000170515 homo_sapiens ENSP00000302886 84.7716 81.4721 rhinopithecus_roxellana ENSRROP00000005822 91.0082 87.4659 ENSG00000170515 homo_sapiens ENSP00000302886 42.132 39.0863 rhinopithecus_roxellana ENSRROP00000010525 86.0104 79.7927 ENSG00000170515 homo_sapiens ENSP00000302886 54.3147 50.2538 rhinopithecus_roxellana ENSRROP00000003716 84.9206 78.5714 ENSG00000170515 homo_sapiens ENSP00000302886 99.4924 99.2386 mus_pahari MGP_PahariEiJ_P0087494 99.4924 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 99.7462 99.2386 propithecus_coquereli ENSPCOP00000008470 99.7462 99.2386 ENSG00000170515 homo_sapiens ENSP00000302886 40.8629 21.5736 caenorhabditis_elegans Y116A8A.9b.1 34.4017 18.1624 ENSG00000170515 homo_sapiens ENSP00000302886 22.335 9.89848 caenorhabditis_elegans W03G9.4.1 14.2857 6.33117 ENSG00000170515 homo_sapiens ENSP00000302886 20.5584 9.39086 caenorhabditis_elegans Y45G5AM.2a.1 7.63431 3.48728 ENSG00000170515 homo_sapiens ENSP00000302886 36.802 19.2893 drosophila_melanogaster FBpp0079462 32.3661 16.9643 ENSG00000170515 homo_sapiens ENSP00000302886 67.0051 62.9442 latimeria_chalumnae ENSLACP00000005716 81.2308 76.3077 ENSG00000170515 homo_sapiens ENSP00000302886 92.8934 87.0558 lepisosteus_oculatus ENSLOCP00000004426 91.7293 85.9649 ENSG00000170515 homo_sapiens ENSP00000302886 86.2944 77.9188 clupea_harengus ENSCHAP00000027897 82.1256 74.1546 ENSG00000170515 homo_sapiens ENSP00000302886 90.3553 82.9949 danio_rerio ENSDARP00000057822 90.8163 83.4184 ENSG00000170515 homo_sapiens ENSP00000302886 89.5939 81.9797 carassius_auratus ENSCARP00000074463 90.051 82.398 ENSG00000170515 homo_sapiens ENSP00000302886 90.1015 81.9797 carassius_auratus ENSCARP00000084122 90.5612 82.398 ENSG00000170515 homo_sapiens ENSP00000302886 88.3249 79.9492 astyanax_mexicanus ENSAMXP00000018643 88.5496 80.1527 ENSG00000170515 homo_sapiens ENSP00000302886 89.5939 80.7107 astyanax_mexicanus ENSAMXP00000037088 90.051 81.1225 ENSG00000170515 homo_sapiens ENSP00000302886 90.3553 81.7259 ictalurus_punctatus ENSIPUP00000034787 90.8163 82.1429 ENSG00000170515 homo_sapiens ENSP00000302886 89.5939 81.9797 esox_lucius ENSELUP00000016562 89.8219 82.1883 ENSG00000170515 homo_sapiens ENSP00000302886 90.8629 82.2335 electrophorus_electricus ENSEEEP00000004675 91.3265 82.6531 ENSG00000170515 homo_sapiens ENSP00000302886 86.0406 76.6497 oncorhynchus_kisutch ENSOKIP00005009803 84.3284 75.1244 ENSG00000170515 homo_sapiens ENSP00000302886 90.6091 82.2335 oncorhynchus_kisutch ENSOKIP00005021649 90.8397 82.4427 ENSG00000170515 homo_sapiens ENSP00000302886 90.3553 81.4721 oncorhynchus_mykiss ENSOMYP00000055877 90.5852 81.6794 ENSG00000170515 homo_sapiens ENSP00000302886 85.533 76.6497 oncorhynchus_mykiss ENSOMYP00000016981 85.533 76.6497 ENSG00000170515 homo_sapiens ENSP00000302886 87.5635 78.1726 salmo_salar ENSSSAP00000043523 89.8438 80.2083 ENSG00000170515 homo_sapiens ENSP00000302886 86.802 77.9188 salmo_salar ENSSSAP00000043479 87.9177 78.9203 ENSG00000170515 homo_sapiens ENSP00000302886 90.6091 81.9797 salmo_trutta ENSSTUP00000007501 90.8397 82.1883 ENSG00000170515 homo_sapiens ENSP00000302886 90.6091 82.9949 salmo_trutta ENSSTUP00000043739 90.8397 83.2061 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 83.5025 fundulus_heteroclitus ENSFHEP00000006482 92.3274 84.1432 ENSG00000170515 homo_sapiens ENSP00000302886 83.2487 75.1269 poecilia_reticulata ENSPREP00000030837 87.0027 78.5146 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 84.5178 poecilia_reticulata ENSPREP00000018462 92.5641 85.3846 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 83.7563 xiphophorus_maculatus ENSXMAP00000001927 92.0716 84.399 ENSG00000170515 homo_sapiens ENSP00000302886 89.8477 82.7411 oryzias_latipes ENSORLP00000036499 90.5371 83.376 ENSG00000170515 homo_sapiens ENSP00000302886 90.3553 82.4873 cyclopterus_lumpus ENSCLMP00005035902 91.0486 83.1202 ENSG00000170515 homo_sapiens ENSP00000302886 91.8782 84.264 oreochromis_niloticus ENSONIP00000077766 92.5831 84.9105 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 83.7563 haplochromis_burtoni ENSHBUP00000007059 92.0716 84.399 ENSG00000170515 homo_sapiens ENSP00000302886 90.8629 83.7563 sparus_aurata ENSSAUP00010035737 91.5601 84.399 ENSG00000170515 homo_sapiens ENSP00000302886 87.0558 80.203 lates_calcarifer ENSLCAP00010038797 87.9487 81.0256 ENSG00000170515 homo_sapiens ENSP00000302886 92.6396 86.5482 xenopus_tropicalis ENSXETP00000074378 90.5707 84.6154 ENSG00000170515 homo_sapiens ENSP00000302886 84.0102 81.2183 chrysemys_picta_bellii ENSCPBP00000017495 97.3529 94.1176 ENSG00000170515 homo_sapiens ENSP00000302886 93.401 87.8173 sphenodon_punctatus ENSSPUP00000019154 88.4615 83.1731 ENSG00000170515 homo_sapiens ENSP00000302886 86.0406 80.203 laticauda_laticaudata ENSLLTP00000021218 94.429 88.0223 ENSG00000170515 homo_sapiens ENSP00000302886 96.1929 89.5939 notechis_scutatus ENSNSUP00000011674 96.1929 89.5939 ENSG00000170515 homo_sapiens ENSP00000302886 96.1929 89.5939 pseudonaja_textilis ENSPTXP00000008703 96.1929 89.5939 ENSG00000170515 homo_sapiens ENSP00000302886 96.1929 91.8782 gallus_gallus ENSGALP00010037397 96.1929 91.8782 ENSG00000170515 homo_sapiens ENSP00000302886 78.6802 69.5431 meleagris_gallopavo ENSMGAP00000025049 64.5833 57.0833 ENSG00000170515 homo_sapiens ENSP00000302886 59.6447 54.3147 serinus_canaria ENSSCAP00000004983 88.6792 80.7547 ENSG00000170515 homo_sapiens ENSP00000302886 94.9239 88.8325 anolis_carolinensis ENSACAP00000004955 94.9239 88.8325 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 83.7563 neolamprologus_brichardi ENSNBRP00000022899 92.3274 84.399 ENSG00000170515 homo_sapiens ENSP00000302886 95.9391 89.5939 naja_naja ENSNNAP00000001933 95.9391 89.5939 ENSG00000170515 homo_sapiens ENSP00000302886 92.3858 85.533 podarcis_muralis ENSPMRP00000003961 91.6877 84.8867 ENSG00000170515 homo_sapiens ENSP00000302886 90.8629 85.0254 geospiza_fortis ENSGFOP00000017402 94.4591 88.3905 ENSG00000170515 homo_sapiens ENSP00000302886 95.4315 89.8477 taeniopygia_guttata ENSTGUP00000037011 95.4315 89.8477 ENSG00000170515 homo_sapiens ENSP00000302886 95.4315 89.8477 taeniopygia_guttata ENSTGUP00000018567 95.4315 89.8477 ENSG00000170515 homo_sapiens ENSP00000302886 93.6548 88.8325 erpetoichthys_calabaricus ENSECRP00000009572 93.6548 88.8325 ENSG00000170515 homo_sapiens ENSP00000302886 91.8782 82.9949 kryptolebias_marmoratus ENSKMAP00000026384 92.5831 83.6317 ENSG00000170515 homo_sapiens ENSP00000302886 95.9391 90.1015 salvator_merianae ENSSMRP00000006087 95.9391 90.1015 ENSG00000170515 homo_sapiens ENSP00000302886 90.6091 84.264 oryzias_javanicus ENSOJAP00000006045 91.3043 84.9105 ENSG00000170515 homo_sapiens ENSP00000302886 88.5787 81.2183 amphilophus_citrinellus ENSACIP00000029448 87.6884 80.402 ENSG00000170515 homo_sapiens ENSP00000302886 90.6091 84.0102 dicentrarchus_labrax ENSDLAP00005025388 91.3043 84.6547 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 84.0102 amphiprion_percula ENSAPEP00000023299 92.0716 84.6547 ENSG00000170515 homo_sapiens ENSP00000302886 89.5939 82.7411 oryzias_sinensis ENSOSIP00000028650 90.2813 83.376 ENSG00000170515 homo_sapiens ENSP00000302886 89.8477 85.533 pelodiscus_sinensis ENSPSIP00000003232 97.2527 92.5824 ENSG00000170515 homo_sapiens ENSP00000302886 95.9391 91.6244 gopherus_evgoodei ENSGEVP00005008191 95.9391 91.6244 ENSG00000170515 homo_sapiens ENSP00000302886 85.2792 82.4873 chelonoidis_abingdonii ENSCABP00000009171 94.9153 91.8079 ENSG00000170515 homo_sapiens ENSP00000302886 91.1168 84.264 seriola_dumerili ENSSDUP00000010411 91.8159 84.9105 ENSG00000170515 homo_sapiens ENSP00000302886 91.1168 82.2335 cottoperca_gobio ENSCGOP00000051304 91.8159 82.8644 ENSG00000170515 homo_sapiens ENSP00000302886 92.3858 87.3096 struthio_camelus_australis ENSSCUP00000025119 84.4548 79.8144 ENSG00000170515 homo_sapiens ENSP00000302886 89.0863 85.533 anser_brachyrhynchus ENSABRP00000004862 96.4286 92.5824 ENSG00000170515 homo_sapiens ENSP00000302886 88.0711 80.9645 cynoglossus_semilaevis ENSCSEP00000004831 88.7468 81.5857 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 83.7563 poecilia_formosa ENSPFOP00000002520 92.3274 84.399 ENSG00000170515 homo_sapiens ENSP00000302886 91.1168 83.7563 myripristis_murdjan ENSMMDP00005046706 91.8159 84.399 ENSG00000170515 homo_sapiens ENSP00000302886 89.3401 81.9797 sander_lucioperca ENSSLUP00000031852 88 80.75 ENSG00000170515 homo_sapiens ENSP00000302886 90.8629 84.0102 strigops_habroptila ENSSHBP00005017118 83.4499 77.1562 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 84.0102 amphiprion_ocellaris ENSAOCP00000022475 92.0716 84.6547 ENSG00000170515 homo_sapiens ENSP00000302886 79.6954 75.1269 terrapene_carolina_triunguis ENSTMTP00000028840 83.5106 78.7234 ENSG00000170515 homo_sapiens ENSP00000302886 90.3553 82.2335 hucho_hucho ENSHHUP00000080416 84.5606 76.9596 ENSG00000170515 homo_sapiens ENSP00000302886 90.6091 82.7411 hucho_hucho ENSHHUP00000053439 90.8397 82.9517 ENSG00000170515 homo_sapiens ENSP00000302886 90.1015 82.2335 betta_splendens ENSBSLP00000041706 90.7928 82.8644 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 83.5025 pygocentrus_nattereri ENSPNAP00000024685 91.8367 83.9286 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 85.0254 anabas_testudineus ENSATEP00000003297 92.3274 85.6777 ENSG00000170515 homo_sapiens ENSP00000302886 37.0558 19.797 saccharomyces_cerevisiae YBL091C 34.6793 18.5273 ENSG00000170515 homo_sapiens ENSP00000302886 88.8325 81.2183 seriola_lalandi_dorsalis ENSSLDP00000032779 89.0585 81.4249 ENSG00000170515 homo_sapiens ENSP00000302886 86.5482 79.4416 labrus_bergylta ENSLBEP00000024631 85.4637 78.4461 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 83.7563 pundamilia_nyererei ENSPNYP00000006880 92.0716 84.399 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 84.7716 mastacembelus_armatus ENSMAMP00000001341 91.6031 84.9873 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 84.0102 stegastes_partitus ENSSPAP00000016322 92.3274 84.6547 ENSG00000170515 homo_sapiens ENSP00000302886 90.8629 82.7411 oncorhynchus_tshawytscha ENSOTSP00005061170 91.0941 82.9517 ENSG00000170515 homo_sapiens ENSP00000302886 90.3553 81.9797 oncorhynchus_tshawytscha ENSOTSP00005015149 90.5852 82.1883 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 83.7563 acanthochromis_polyacanthus ENSAPOP00000012769 92.3274 84.399 ENSG00000170515 homo_sapiens ENSP00000302886 96.1929 92.132 aquila_chrysaetos_chrysaetos ENSACCP00020021451 96.1929 92.132 ENSG00000170515 homo_sapiens ENSP00000302886 85.7868 76.9036 nothobranchius_furzeri ENSNFUP00015025954 85.5696 76.7089 ENSG00000170515 homo_sapiens ENSP00000302886 91.6244 84.5178 cyprinodon_variegatus ENSCVAP00000020106 92.3274 85.1662 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 83.5025 denticeps_clupeoides ENSDCDP00000036938 91.8367 83.9286 ENSG00000170515 homo_sapiens ENSP00000302886 91.1168 84.0102 larimichthys_crocea ENSLCRP00005026240 91.8159 84.6547 ENSG00000170515 homo_sapiens ENSP00000302886 89.0863 82.2335 takifugu_rubripes ENSTRUP00000028970 89.7698 82.8644 ENSG00000170515 homo_sapiens ENSP00000302886 78.934 74.1117 ficedula_albicollis ENSFALP00000011364 88.102 82.7195 ENSG00000170515 homo_sapiens ENSP00000302886 17.7665 14.9746 hippocampus_comes ENSHCOP00000014855 82.3529 69.4118 ENSG00000170515 homo_sapiens ENSP00000302886 83.5025 77.1574 hippocampus_comes ENSHCOP00000018933 92.1569 85.1541 ENSG00000170515 homo_sapiens ENSP00000302886 89.3401 82.2335 cyprinus_carpio_carpio ENSCCRP00000155780 89.7959 82.6531 ENSG00000170515 homo_sapiens ENSP00000302886 89.8477 82.7411 cyprinus_carpio_carpio ENSCCRP00000092164 90.3061 83.1633 ENSG00000170515 homo_sapiens ENSP00000302886 89.5939 84.264 coturnix_japonica ENSCJPP00005003321 89.3671 84.0506 ENSG00000170515 homo_sapiens ENSP00000302886 88.5787 80.9645 poecilia_latipinna ENSPLAP00000022472 82.7014 75.5924 ENSG00000170515 homo_sapiens ENSP00000302886 89.8477 82.4873 sinocyclocheilus_grahami ENSSGRP00000096636 90.0763 82.6972 ENSG00000170515 homo_sapiens ENSP00000302886 91.1168 83.7563 maylandia_zebra ENSMZEP00005012198 84.6698 77.8302 ENSG00000170515 homo_sapiens ENSP00000302886 88.3249 82.2335 tetraodon_nigroviridis ENSTNIP00000017625 88.7755 82.6531 ENSG00000170515 homo_sapiens ENSP00000302886 90.6091 82.4873 paramormyrops_kingsleyae ENSPKIP00000023685 83.8028 76.2911 ENSG00000170515 homo_sapiens ENSP00000302886 92.8934 87.3096 scleropages_formosus ENSSFOP00015023760 93.6061 87.9795 ENSG00000170515 homo_sapiens ENSP00000302886 91.3706 84.7716 scleropages_formosus ENSSFOP00015008003 92.0716 85.422 ENSG00000170515 homo_sapiens ENSP00000302886 86.5482 82.2335 leptobrachium_leishanense ENSLLEP00000014361 85.0374 80.798 ENSG00000170515 homo_sapiens ENSP00000302886 91.1168 83.5025 scophthalmus_maximus ENSSMAP00000042539 91.8159 84.1432 ENSG00000170515 homo_sapiens ENSP00000302886 90.6091 83.5025 oryzias_melastigma ENSOMEP00000008508 91.3043 84.1432
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003676 enables nucleic acid binding 1 IDA Homo_sapiens(9606) Function GO:0003714 enables transcription corepressor activity 1 IDA Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005576 located_in extracellular region 1 TAS Homo_sapiens(9606) Component GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 IDA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0006364 involved_in rRNA processing 1 IEA Homo_sapiens(9606) Process GO:0006417 involved_in regulation of translation 1 IEA Homo_sapiens(9606) Process GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0031625 enables ubiquitin protein ligase binding 1 IPI Homo_sapiens(9606) Function GO:0035578 located_in azurophil granule lumen 1 TAS Homo_sapiens(9606) Component GO:0043066 involved_in negative regulation of apoptotic process 1 ISS Homo_sapiens(9606) Process GO:0045597 involved_in positive regulation of cell differentiation 1 ISS Homo_sapiens(9606) Process GO:0045892 acts_upstream_of_or_within negative regulation of DNA-templated transcription 1 IDA Homo_sapiens(9606) Process GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component GO:1990904 part_of ribonucleoprotein complex 1 IEA Homo_sapiens(9606) Component
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