Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000170365 Gene ID 4086 Accession 6767
Symbol SMAD1 Alias BSP1;JV41;BSP-1;JV4-1;MADH1;MADR1 Full Name SMAD family member 1
Status Confidence Length 77983 bases Strand Plus strand
Position 4 : 145481194 - 145559176 RNA binding domain N.A.
Summary The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
SMAD1-213 ENST00000514778 616 106aa ENSP00000424959
SMAD1-207 ENST00000507594 558 95aa ENSP00000424649
SMAD1-214 ENST00000514831 569 112aa ENSP00000425270
SMAD1-201 ENST00000302085 3002 465aa ENSP00000305769
SMAD1-211 ENST00000512019 847 133aa ENSP00000427002
SMAD1-204 ENST00000503324 573 58aa ENSP00000422706
SMAD1-216 ENST00000515527 632 No protein -
SMAD1-206 ENST00000507367 421 10aa ENSP00000421601
SMAD1-202 ENST00000394092 1658 465aa ENSP00000377652
SMAD1-215 ENST00000515385 2085 465aa ENSP00000426568
SMAD1-212 ENST00000514168 548 No protein -
SMAD1-205 ENST00000506626 518 No protein -
SMAD1-203 ENST00000502342 262 No protein -
SMAD1-209 ENST00000511125 3293 No protein -
SMAD1-208 ENST00000510948 569 No protein -
SMAD1-210 ENST00000511255 539 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
59545Blood Pressure1.8857609E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000170365homo_sapiensENSP0000036915487.580380.7281homo_sapiensENSP0000030576987.95781.0753
ENSG00000170365homo_sapiensENSP0000026216071.306260.5996homo_sapiensENSP0000030576971.612960.8602
ENSG00000170365homo_sapiensENSP0000033297377.647166.8235homo_sapiensENSP0000030576970.967761.0753
ENSG00000170365homo_sapiensENSP0000044195493.118389.8925homo_sapiensENSP0000030576993.118389.8925
ENSG00000170365homo_sapiensENSP0000028884036.088725.2016homo_sapiensENSP0000030576938.494626.8817
ENSG00000170365homo_sapiensENSP0000034155146.376833.1522homo_sapiensENSP0000030576955.053839.3548
ENSG00000170365homo_sapiensENSP0000026215840.140826.7606homo_sapiensENSP0000030576936.774224.5161

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000170365homo_sapiensENSP0000030576910099.7849nomascus_leucogenysENSNLEP0000000670210099.7849
ENSG00000170365homo_sapiensENSP0000030576910099.7849pan_paniscusENSPPAP0000000872710099.7849
ENSG00000170365homo_sapiensENSP0000030576910099.7849pongo_abeliiENSPPYP0000002704499.785499.5708
ENSG00000170365homo_sapiensENSP0000030576999.139898.9247pan_troglodytesENSPTRP0000002829798.294298.081
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849gorilla_gorillaENSGGOP0000002561599.784999.7849
ENSG00000170365homo_sapiensENSP0000030576998.709798.2796ornithorhynchus_anatinusENSOANP0000005063998.709798.2796
ENSG00000170365homo_sapiensENSP0000030576999.354899.1398sarcophilus_harrisiiENSSHAP0000000734599.354899.1398
ENSG00000170365homo_sapiensENSP0000030576967.526966.8817notamacropus_eugeniiENSMEUP0000000577999.053698.1073
ENSG00000170365homo_sapiensENSP0000030576984.516184.5161choloepus_hoffmanniENSCHOP0000000819090.762190.7621
ENSG00000170365homo_sapiensENSP0000030576999.354898.2796dasypus_novemcinctusENSDNOP0000002475096.2595.2083
ENSG00000170365homo_sapiensENSP0000030576999.354898.9247erinaceus_europaeusENSEEUP0000000762299.56999.1379
ENSG00000170365homo_sapiensENSP0000030576981.720480.2151echinops_telfairiENSETEP0000001341584.444482.8889
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849callithrix_jacchusENSCJAP0000000464099.570899.5708
ENSG00000170365homo_sapiensENSP00000305769100100cercocebus_atysENSCATP00000035595100100
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849macaca_fascicularisENSMFAP0000003704599.784999.7849
ENSG00000170365homo_sapiensENSP00000305769100100macaca_mulattaENSMMUP00000024174100100
ENSG00000170365homo_sapiensENSP00000305769100100macaca_nemestrinaENSMNEP00000006142100100
ENSG00000170365homo_sapiensENSP00000305769100100papio_anubisENSPANP00000015391100100
ENSG00000170365homo_sapiensENSP00000305769100100mandrillus_leucophaeusENSMLEP00000019537100100
ENSG00000170365homo_sapiensENSP0000030576999.784998.9247tursiops_truncatusENSTTRP0000000764699.784998.9247
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548vulpes_vulpesENSVVUP0000001254299.569999.3548
ENSG00000170365homo_sapiensENSP0000030576999.569999.1398mus_spretusMGP_SPRETEiJ_P008859999.569999.1398
ENSG00000170365homo_sapiensENSP0000030576999.569999.5699equus_asinusENSEASP0000500199499.569999.5699
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849capra_hircusENSCHIP0000000798499.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.784999.5699loxodonta_africanaENSLAFP0000001537499.784999.5699
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548panthera_leoENSPLOP0000001669699.569999.3548
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548ailuropoda_melanoleucaENSAMEP0000001758399.569999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849bos_indicus_hybridENSBIXP0000500225499.784999.7849
ENSG00000170365homo_sapiensENSP0000030576998.494697.6344oryctolagus_cuniculusENSOCUP0000003429498.494697.6344
ENSG00000170365homo_sapiensENSP0000030576999.569999.5699equus_caballusENSECAP0000002035599.569999.5699
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548canis_lupus_familiarisENSCAFP0084501692099.569999.3548
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548panthera_pardusENSPPRP0000000081599.569999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849marmota_marmota_marmotaENSMMMP0000000167099.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548balaenoptera_musculusENSBMSP0001000353599.569999.3548
ENSG00000170365homo_sapiensENSP0000030576998.924798.9247cavia_porcellusENSCPOP0000000814698.924798.9247
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548felis_catusENSFCAP0000000381099.569999.3548
ENSG00000170365homo_sapiensENSP0000030576933.333332.043ursus_americanusENSUAMP0000000075691.176587.6471
ENSG00000170365homo_sapiensENSP0000030576999.784999.3548monodelphis_domesticaENSMODP0000000059599.784999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849bison_bison_bisonENSBBBP0000001299099.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.784999.3548monodon_monocerosENSMMNP0001502273599.784999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849sus_scrofaENSSSCP0000003266099.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.784999.5699microcebus_murinusENSMICP0000001658999.784999.5699
ENSG00000170365homo_sapiensENSP0000030576998.924798.7097octodon_degusENSODEP0000000294798.924798.7097
ENSG00000170365homo_sapiensENSP0000030576989.462488.6021jaculus_jaculusENSJJAP0000001606496.969796.0373
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849jaculus_jaculusENSJJAP0000001764899.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849ovis_aries_rambouilletENSOARP0002003230699.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548ursus_maritimusENSUMAP0000002131799.569999.3548
ENSG00000170365homo_sapiensENSP0000030576987.311886.8817ochotona_princepsENSOPRP0000001165699.024498.5366
ENSG00000170365homo_sapiensENSP0000030576999.784999.3548delphinapterus_leucasENSDLEP0000002200899.784999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.1398physeter_catodonENSPCTP0000500237799.784999.1398
ENSG00000170365homo_sapiensENSP0000030576999.569999.1398mus_caroliMGP_CAROLIEiJ_P008509199.569999.1398
ENSG00000170365homo_sapiensENSP0000030576999.569999.1398mus_musculusENSMUSP0000007103599.569999.1398
ENSG00000170365homo_sapiensENSP0000030576999.354898.7097dipodomys_ordiiENSDORP0000000757099.354898.7097
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548mustela_putorius_furoENSMPUP0000000681299.569999.3548
ENSG00000170365homo_sapiensENSP0000030576910099.7849aotus_nancymaaeENSANAP0000003684510099.7849
ENSG00000170365homo_sapiensENSP00000305769100100saimiri_boliviensis_boliviensisENSSBOP00000032926100100
ENSG00000170365homo_sapiensENSP0000030576977.419476.5591vicugna_pacosENSVPAP0000000309199.173698.0716
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849chlorocebus_sabaeusENSCSAP0000001462099.784999.7849
ENSG00000170365homo_sapiensENSP0000030576971.182871.1828tupaia_belangeriENSTBEP0000001429599.698899.6988
ENSG00000170365homo_sapiensENSP0000030576999.354899.1398mesocricetus_auratusENSMAUP0000002278199.354899.1398
ENSG00000170365homo_sapiensENSP0000030576999.784999.3548phocoena_sinusENSPSNP0000001943799.784999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.3548camelus_dromedariusENSCDRP0000500001499.784999.3548
ENSG00000170365homo_sapiensENSP0000030576910099.7849carlito_syrichtaENSTSYP0000001406710099.7849
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548panthera_tigris_altaicaENSPTIP0000002398299.569999.3548
ENSG00000170365homo_sapiensENSP0000030576999.139898.7097rattus_norvegicusENSRNOP0000002507995.445195.0311
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849prolemur_simusENSPSMP0000002493999.570899.5708
ENSG00000170365homo_sapiensENSP0000030576999.354898.7097microtus_ochrogasterENSMOCP0000000353499.354898.7097
ENSG00000170365homo_sapiensENSP0000030576961.720461.0753sorex_araneusENSSARP0000000239786.969786.0606
ENSG00000170365homo_sapiensENSP0000030576999.569999.1398peromyscus_maniculatus_bairdiiENSPEMP0000002045399.569999.1398
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849bos_mutusENSBMUP0000000814699.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.569999.1398mus_spicilegusENSMSIP0000003511299.569999.1398
ENSG00000170365homo_sapiensENSP0000030576992.04390.9677cricetulus_griseus_chok1gshdENSCGRP0000100506591.845590.7725
ENSG00000170365homo_sapiensENSP0000030576939.569937.2043cricetulus_griseus_chok1gshdENSCGRP0000101049292.462386.9347
ENSG00000170365homo_sapiensENSP0000030576930.752729.2473cricetulus_griseus_chok1gshdENSCGRP0000101138391.666787.1795
ENSG00000170365homo_sapiensENSP0000030576976.989373.3333cricetulus_griseus_chok1gshdENSCGRP0000100169793.229288.8021
ENSG00000170365homo_sapiensENSP000003057692018.9247cricetulus_griseus_chok1gshdENSCGRP0000100198790.291385.4369
ENSG00000170365homo_sapiensENSP0000030576946.881744.086cricetulus_griseus_chok1gshdENSCGRP0000101040681.040976.2082
ENSG00000170365homo_sapiensENSP0000030576999.354898.9247pteropus_vampyrusENSPVAP0000001347599.354898.9247
ENSG00000170365homo_sapiensENSP0000030576999.569999.5699myotis_lucifugusENSMLUP0000001116899.569999.5699
ENSG00000170365homo_sapiensENSP0000030576999.784999.3548vombatus_ursinusENSVURP0001001360699.784999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.5699rhinolophus_ferrumequinumENSRFEP0001002196499.784999.5699
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548neovison_visonENSNVIP0000001080799.569999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849bos_taurusENSBTAP0000007445699.784999.7849
ENSG00000170365homo_sapiensENSP0000030576945.806444.086heterocephalus_glaber_femaleENSHGLP0000004798591.025687.6068
ENSG00000170365homo_sapiensENSP0000030576945.591443.4409heterocephalus_glaber_femaleENSHGLP0000004349590.598386.3248
ENSG00000170365homo_sapiensENSP0000030576984.946281.7204heterocephalus_glaber_femaleENSHGLP0000002492994.951991.3462
ENSG00000170365homo_sapiensENSP0000030576984.731283.4409heterocephalus_glaber_femaleENSHGLP0000001053295.169193.7198
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548heterocephalus_glaber_femaleENSHGLP0000000023299.569999.3548
ENSG00000170365homo_sapiensENSP00000305769100100rhinopithecus_bietiENSRBIP00000016921100100
ENSG00000170365homo_sapiensENSP0000030576999.569999.3548canis_lupus_dingoENSCAFP0002003328299.569999.3548
ENSG00000170365homo_sapiensENSP0000030576999.784999.5699sciurus_vulgarisENSSVLP0000501209899.784999.5699
ENSG00000170365homo_sapiensENSP0000030576995.268890.1075sciurus_vulgarisENSSVLP0000501330295.887490.6926
ENSG00000170365homo_sapiensENSP0000030576999.784999.3548phascolarctos_cinereusENSPCIP0000001770099.784999.3548
ENSG00000170365homo_sapiensENSP0000030576964.731264.7312procavia_capensisENSPCAP0000000852065.292865.2928
ENSG00000170365homo_sapiensENSP0000030576999.354899.1398nannospalax_galiliENSNGAP0000000845499.354899.1398
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849bos_grunniensENSBGRP0000001217399.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.139898.9247chinchilla_lanigeraENSCLAP0000000701999.139898.9247
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849cervus_hanglu_yarkandensisENSCHYP0000000206299.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.569998.9247catagonus_wagneriENSCWAP0000001302699.569998.9247
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849ictidomys_tridecemlineatusENSSTOP0000000971799.784999.7849
ENSG00000170365homo_sapiensENSP0000030576999.354899.1398otolemur_garnettiiENSOGAP0000000013399.354899.1398
ENSG00000170365homo_sapiensENSP00000305769100100cebus_imitatorENSCCAP00000027710100100
ENSG00000170365homo_sapiensENSP0000030576999.784999.5699urocitellus_parryiiENSUPAP0001000055599.784999.5699
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849moschus_moschiferusENSMMSP0000001427599.784999.7849
ENSG00000170365homo_sapiensENSP00000305769100100rhinopithecus_roxellanaENSRROP00000038071100100
ENSG00000170365homo_sapiensENSP0000030576999.569999.1398mus_pahariMGP_PahariEiJ_P005339699.569999.1398
ENSG00000170365homo_sapiensENSP0000030576999.784999.7849propithecus_coquereliENSPCOP0000000547999.784999.7849
ENSG00000170365homo_sapiensENSP0000030576928.817227.0968ciona_intestinalisENSCINP0000003027492.413886.8966
ENSG00000170365homo_sapiensENSP0000030576934.408631.1828callorhinchus_miliiENSCMIP0000004538980.40272.8643
ENSG00000170365homo_sapiensENSP0000030576998.064597.2043latimeria_chalumnaeENSLACP0000001277198.064597.2043
ENSG00000170365homo_sapiensENSP0000030576996.344193.1183lepisosteus_oculatusENSLOCP0000001080895.726592.5214
ENSG00000170365homo_sapiensENSP0000030576994.193689.6774clupea_harengusENSCHAP0000004144082.641578.6792
ENSG00000170365homo_sapiensENSP0000030576994.838789.6774danio_rerioENSDARP0000003015093.432288.3475
ENSG00000170365homo_sapiensENSP0000030576994.408689.0323carassius_auratusENSCARP0000008656893.008587.7119
ENSG00000170365homo_sapiensENSP0000030576994.193689.0323carassius_auratusENSCARP0000005116592.796687.7119
ENSG00000170365homo_sapiensENSP0000030576988.602181.0753astyanax_mexicanusENSAMXP0000004032684.426277.2541
ENSG00000170365homo_sapiensENSP0000030576994.838789.2473ictalurus_punctatusENSIPUP0000000676193.432287.9237
ENSG00000170365homo_sapiensENSP0000030576994.838789.6774esox_luciusENSELUP0000001441793.234788.1607
ENSG00000170365homo_sapiensENSP0000030576991.182885.3763esox_luciusENSELUP0000000612989.451583.7553
ENSG00000170365homo_sapiensENSP0000030576969.892562.5806electrophorus_electricusENSEEEP0000001283073.198265.5405
ENSG00000170365homo_sapiensENSP0000030576995.268890.9677oncorhynchus_kisutchENSOKIP0000500763092.099887.9418
ENSG00000170365homo_sapiensENSP0000030576995.268890.9677oncorhynchus_kisutchENSOKIP0000506343885.686781.8182
ENSG00000170365homo_sapiensENSP0000030576995.268890.9677oncorhynchus_mykissENSOMYP0000002470379.676376.0791
ENSG00000170365homo_sapiensENSP0000030576990.537683.871oncorhynchus_mykissENSOMYP0000011532988.818682.2785
ENSG00000170365homo_sapiensENSP0000030576995.268890.9677oncorhynchus_mykissENSOMYP0000002465492.099887.9418
ENSG00000170365homo_sapiensENSP0000030576990.537683.6559salmo_salarENSSSAP0000004103486.983580.3719
ENSG00000170365homo_sapiensENSP0000030576995.268890.9677salmo_salarENSSSAP0000010365392.099887.9418
ENSG00000170365homo_sapiensENSP0000030576995.268890.9677salmo_salarENSSSAP0000012484874.831171.4527
ENSG00000170365homo_sapiensENSP0000030576995.268890.9677salmo_truttaENSSTUP0000000251692.099887.9418
ENSG00000170365homo_sapiensENSP0000030576995.483990.9677salmo_truttaENSSTUP0000002537192.307787.9418
ENSG00000170365homo_sapiensENSP0000030576990.967784.086salmo_truttaENSSTUP0000000213689.240582.4894
ENSG00000170365homo_sapiensENSP0000030576995.053890.1075gadus_morhuaENSGMOP0000006604592.275687.4739
ENSG00000170365homo_sapiensENSP0000030576987.741978.2796gadus_morhuaENSGMOP0000002516886.440777.1186
ENSG00000170365homo_sapiensENSP0000030576995.483990.3226fundulus_heteroclitusENSFHEP0000000679690.983686.0656
ENSG00000170365homo_sapiensENSP0000030576995.268889.6774poecilia_reticulataENSPREP0000003432894.860889.2934
ENSG00000170365homo_sapiensENSP0000030576995.268889.6774xiphophorus_maculatusENSXMAP0000003208289.314584.0726
ENSG00000170365homo_sapiensENSP0000030576995.053890.1075oryzias_latipesENSORLP0000000924793.842988.9597
ENSG00000170365homo_sapiensENSP0000030576994.838789.6774cyclopterus_lumpusENSCLMP0000500906793.829888.7234
ENSG00000170365homo_sapiensENSP0000030576995.483990.7527oreochromis_niloticusENSONIP0000001257794.871890.1709
ENSG00000170365homo_sapiensENSP0000030576995.698990.9677haplochromis_burtoniENSHBUP0000002609595.289190.5782
ENSG00000170365homo_sapiensENSP0000030576995.698990.9677astatotilapia_callipteraENSACLP0000003779595.289190.5782
ENSG00000170365homo_sapiensENSP0000030576996.12991.1828sparus_aurataENSSAUP0001001759895.106490.2128
ENSG00000170365homo_sapiensENSP0000030576994.623789.8925lates_calcariferENSLCAP0001004171895.238190.4762
ENSG00000170365homo_sapiensENSP0000030576997.634495.914xenopus_tropicalisENSXETP0000005111797.844896.1207
ENSG00000170365homo_sapiensENSP0000030576998.924798.4946chrysemys_picta_belliiENSCPBP0000003993898.924798.4946
ENSG00000170365homo_sapiensENSP0000030576998.494698.0645sphenodon_punctatusENSSPUP0000001136198.494698.0645
ENSG00000170365homo_sapiensENSP0000030576998.709798.4946crocodylus_porosusENSCPRP0000501204298.709798.4946
ENSG00000170365homo_sapiensENSP0000030576963.440962.7957laticauda_laticaudataENSLLTP0000002500198.333397.3333
ENSG00000170365homo_sapiensENSP0000030576998.924798.0645notechis_scutatusENSNSUP0000000623498.924798.0645
ENSG00000170365homo_sapiensENSP0000030576998.924798.0645pseudonaja_textilisENSPTXP0000001466298.924798.0645
ENSG00000170365homo_sapiensENSP0000030576998.279697.2043anas_platyrhynchos_platyrhynchosENSAPLP0000001189698.279697.2043
ENSG00000170365homo_sapiensENSP0000030576998.279697.2043gallus_gallusENSGALP0001000896298.279697.2043
ENSG00000170365homo_sapiensENSP0000030576998.279696.7742meleagris_gallopavoENSMGAP0000000348798.279696.7742
ENSG00000170365homo_sapiensENSP0000030576998.494696.7742serinus_canariaENSSCAP0000002086198.494696.7742
ENSG00000170365homo_sapiensENSP0000030576998.494696.9893parus_majorENSPMJP0000001138698.494696.9893
ENSG00000170365homo_sapiensENSP0000030576998.494697.6344anolis_carolinensisENSACAP0000000347498.494697.6344
ENSG00000170365homo_sapiensENSP0000030576995.698990.9677neolamprologus_brichardiENSNBRP0000000594395.289190.5782
ENSG00000170365homo_sapiensENSP0000030576998.924798.2796naja_najaENSNNAP0000001600998.924798.2796
ENSG00000170365homo_sapiensENSP0000030576998.064597.4194podarcis_muralisENSPMRP0000002048198.488197.8402
ENSG00000170365homo_sapiensENSP0000030576998.279696.5591geospiza_fortisENSGFOP0000001299698.279696.5591
ENSG00000170365homo_sapiensENSP0000030576998.279696.7742taeniopygia_guttataENSTGUP0000000275998.279696.7742
ENSG00000170365homo_sapiensENSP0000030576997.634494.4086erpetoichthys_calabaricusENSECRP0000000184696.390793.2059
ENSG00000170365homo_sapiensENSP0000030576994.408689.2473kryptolebias_marmoratusENSKMAP0000000531994.004388.8651
ENSG00000170365homo_sapiensENSP0000030576998.494698.0645salvator_merianaeENSSMRP0000000030698.494698.0645
ENSG00000170365homo_sapiensENSP0000030576993.548488.6021oryzias_javanicusENSOJAP0000004626394.155889.1775
ENSG00000170365homo_sapiensENSP0000030576995.698990.9677amphilophus_citrinellusENSACIP0000002164895.289190.5782
ENSG00000170365homo_sapiensENSP0000030576995.91490.9677dicentrarchus_labraxENSDLAP0000504090395.095990.1919
ENSG00000170365homo_sapiensENSP0000030576995.91490.9677amphiprion_perculaENSAPEP0000003389195.503290.5782
ENSG00000170365homo_sapiensENSP0000030576995.268890.3226oryzias_sinensisENSOSIP0000004233394.055289.172
ENSG00000170365homo_sapiensENSP0000030576988.602188.3871pelodiscus_sinensisENSPSIP0000001854896.487196.2529
ENSG00000170365homo_sapiensENSP0000030576997.419497.2043gopherus_evgoodeiENSGEVP0000502401495.974695.7627
ENSG00000170365homo_sapiensENSP0000030576998.924798.7097chelonoidis_abingdoniiENSCABP0000002753997.251697.0402
ENSG00000170365homo_sapiensENSP0000030576995.91491.1828seriola_dumeriliENSSDUP0000002843195.503290.7923
ENSG00000170365homo_sapiensENSP0000030576989.892584.3011cottoperca_gobioENSCGOP0000001497288.559383.0508
ENSG00000170365homo_sapiensENSP0000030576997.849596.9893struthio_camelus_australisENSSCUP0000002233197.849596.9893
ENSG00000170365homo_sapiensENSP0000030576998.279697.2043anser_brachyrhynchusENSABRP0000001669598.279697.2043
ENSG00000170365homo_sapiensENSP0000030576995.053890.3226gasterosteus_aculeatusENSGACP0000002275394.042689.3617
ENSG00000170365homo_sapiensENSP0000030576994.623789.0323cynoglossus_semilaevisENSCSEP0000000052693.61788.0851
ENSG00000170365homo_sapiensENSP0000030576995.268889.6774poecilia_formosaENSPFOP0000002856790.040684.7561
ENSG00000170365homo_sapiensENSP0000030576988.17281.5054myripristis_murdjanENSMMDP0000500439288.17281.5054
ENSG00000170365homo_sapiensENSP0000030576995.91491.3979myripristis_murdjanENSMMDP0000501653695.503291.0064
ENSG00000170365homo_sapiensENSP0000030576995.698990.3226sander_luciopercaENSSLUP0000001750394.680989.3617
ENSG00000170365homo_sapiensENSP0000030576998.494697.4194strigops_habroptilaENSSHBP0000502014098.494697.4194
ENSG00000170365homo_sapiensENSP0000030576995.91490.9677amphiprion_ocellarisENSAOCP0000001961195.503290.5782
ENSG00000170365homo_sapiensENSP0000030576998.924798.4946terrapene_carolina_triunguisENSTMTP0000002135398.924798.4946
ENSG00000170365homo_sapiensENSP0000030576995.268890.7527hucho_huchoENSHHUP0000007170693.657589.2178
ENSG00000170365homo_sapiensENSP0000030576995.268890.7527hucho_huchoENSHHUP0000008065392.099887.7339
ENSG00000170365homo_sapiensENSP0000030576993.548489.2473betta_splendensENSBSLP0000000052594.771290.4139
ENSG00000170365homo_sapiensENSP0000030576994.623789.2473pygocentrus_nattereriENSPNAP0000003147693.220387.9237
ENSG00000170365homo_sapiensENSP0000030576994.193689.6774anabas_testudineusENSATEP0000001823995.424890.8497
ENSG00000170365homo_sapiensENSP0000030576995.91491.1828seriola_lalandi_dorsalisENSSLDP0000003292995.503290.7923
ENSG00000170365homo_sapiensENSP0000030576986.666783.0107labrus_bergyltaENSLBEP0000002389396.411592.3445
ENSG00000170365homo_sapiensENSP0000030576995.698990.9677pundamilia_nyerereiENSPNYP0000001648495.289190.5782
ENSG00000170365homo_sapiensENSP0000030576995.91490.9677mastacembelus_armatusENSMAMP0000002100795.299190.3846
ENSG00000170365homo_sapiensENSP0000030576995.91491.1828stegastes_partitusENSSPAP0000000412495.503290.7923
ENSG00000170365homo_sapiensENSP0000030576950.967746.4516oncorhynchus_tshawytschaENSOTSP0000508253363.257.6
ENSG00000170365homo_sapiensENSP0000030576995.91491.1828acanthochromis_polyacanthusENSAPOP0000001659695.503290.7923
ENSG00000170365homo_sapiensENSP0000030576998.494697.6344aquila_chrysaetos_chrysaetosENSACCP0002000608798.494697.6344
ENSG00000170365homo_sapiensENSP0000030576989.247382.1505nothobranchius_furzeriENSNFUP0001500588485.743878.9256
ENSG00000170365homo_sapiensENSP0000030576995.268889.8925cyprinodon_variegatusENSCVAP0000000105394.860889.5075
ENSG00000170365homo_sapiensENSP0000030576991.397986.4516denticeps_clupeoidesENSDCDP0000003366689.473784.6316
ENSG00000170365homo_sapiensENSP0000030576995.483990.7527larimichthys_croceaENSLCRP0000502688094.669589.9787
ENSG00000170365homo_sapiensENSP0000030576996.12990.3226takifugu_rubripesENSTRUP0000003666695.309289.5522
ENSG00000170365homo_sapiensENSP0000030576998.494696.9893ficedula_albicollisENSFALP0000000575798.494696.9893
ENSG00000170365homo_sapiensENSP0000030576994.838789.4624hippocampus_comesENSHCOP0000000414594.838789.4624
ENSG00000170365homo_sapiensENSP0000030576994.623788.6021cyprinus_carpio_carpioENSCCRP0000005111293.220387.2881
ENSG00000170365homo_sapiensENSP0000030576994.408689.0323cyprinus_carpio_carpioENSCCRP0000005111093.008587.7119
ENSG00000170365homo_sapiensENSP0000030576998.279697.2043coturnix_japonicaENSCJPP0000500174398.279697.2043
ENSG00000170365homo_sapiensENSP0000030576995.268889.6774poecilia_latipinnaENSPLAP0000000206294.860889.2934
ENSG00000170365homo_sapiensENSP0000030576985.376380sinocyclocheilus_grahamiENSSGRP0000006261786.681281.2227
ENSG00000170365homo_sapiensENSP0000030576983.225878.4946sinocyclocheilus_grahamiENSSGRP0000001397687.556682.5792
ENSG00000170365homo_sapiensENSP0000030576995.698990.9677maylandia_zebraENSMZEP0000501228395.289190.5782
ENSG00000170365homo_sapiensENSP0000030576995.91490.1075tetraodon_nigroviridisENSTNIP0000002087094.893689.1489
ENSG00000170365homo_sapiensENSP0000030576950.107546.2366paramormyrops_kingsleyaeENSPKIP0000003815478.451272.3906
ENSG00000170365homo_sapiensENSP0000030576994.623789.0323scleropages_formosusENSSFOP0001502576094.218488.651
ENSG00000170365homo_sapiensENSP0000030576996.989394.8387leptobrachium_leishanenseENSLLEP0000000361997.198395.0431
ENSG00000170365homo_sapiensENSP0000030576995.268889.2473scophthalmus_maximusENSSMAP0000000752894.658188.6752
ENSG00000170365homo_sapiensENSP0000030576995.053890.1075oryzias_melastigmaENSOMEP0000000273393.842988.9597

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000165involved_in MAPK cascade1IEAHomo_sapiens(9606)Process
GO:0000785part_of chromatin1ISAHomo_sapiens(9606)Component
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific2IBA,ISAHomo_sapiens(9606)Function
GO:0001228enables DNA-binding transcription activator activity, RNA polymerase II-specific1IDAHomo_sapiens(9606)Function
GO:0001503involved_in ossification1IGIHomo_sapiens(9606)Process
GO:0001657involved_in ureteric bud development1IEAHomo_sapiens(9606)Process
GO:0001710involved_in mesodermal cell fate commitment1IEAHomo_sapiens(9606)Process
GO:0002051involved_in osteoblast fate commitment1IEAHomo_sapiens(9606)Process
GO:0003161involved_in cardiac conduction system development1NASHomo_sapiens(9606)Process
GO:0003700enables DNA-binding transcription factor activity1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus4IDA,ISS,NAS,TASHomo_sapiens(9606)Component
GO:0005637located_in nuclear inner membrane1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm2IDA,ISSHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006351involved_in DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0006357involved_in regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0006366involved_in transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0006468involved_in protein phosphorylation1IEAHomo_sapiens(9606)Process
GO:0006954involved_in inflammatory response1IEAHomo_sapiens(9606)Process
GO:0007165involved_in signal transduction1NASHomo_sapiens(9606)Process
GO:0007179involved_in transforming growth factor beta receptor signaling pathway3IBA,IDA,NASHomo_sapiens(9606)Process
GO:0007276involved_in gamete generation1IEAHomo_sapiens(9606)Process
GO:0008285involved_in negative regulation of cell population proliferation1IEAHomo_sapiens(9606)Process
GO:0009653involved_in anatomical structure morphogenesis1IBAHomo_sapiens(9606)Process
GO:0009880involved_in embryonic pattern specification1ISSHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1IDAHomo_sapiens(9606)Process
GO:0016020located_in membrane1NASHomo_sapiens(9606)Component
GO:0017151enables DEAD/H-box RNA helicase binding1IPIHomo_sapiens(9606)Function
GO:0019901enables protein kinase binding1IPIHomo_sapiens(9606)Function
GO:0030154involved_in cell differentiation1IBAHomo_sapiens(9606)Process
GO:0030509involved_in BMP signaling pathway5IBA,IDA,IMP,ISS,TASHomo_sapiens(9606)Process
GO:0030901involved_in midbrain development1IEAHomo_sapiens(9606)Process
GO:0030902involved_in hindbrain development1IEAHomo_sapiens(9606)Process
GO:0031053involved_in primary miRNA processing1TASHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0042592involved_in homeostatic process1IEAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0045669involved_in positive regulation of osteoblast differentiation1IEAHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II2IC,IDAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0051148involved_in negative regulation of muscle cell differentiation1IEAHomo_sapiens(9606)Process
GO:0051216involved_in cartilage development1IEAHomo_sapiens(9606)Process
GO:0060038involved_in cardiac muscle cell proliferation1IEAHomo_sapiens(9606)Process
GO:0060348involved_in bone development1IEAHomo_sapiens(9606)Process
GO:0060395involved_in SMAD protein signal transduction4IBA,IGI,ISS,NASHomo_sapiens(9606)Process
GO:0061036involved_in positive regulation of cartilage development1IEAHomo_sapiens(9606)Process
GO:0070410enables co-SMAD binding1IPIHomo_sapiens(9606)Function
GO:0070411enables I-SMAD binding2IBA,IPIHomo_sapiens(9606)Function
GO:0070878enables primary miRNA binding1IEAHomo_sapiens(9606)Function
GO:0071141part_of SMAD protein complex1NASHomo_sapiens(9606)Component
GO:0071142part_of homomeric SMAD protein complex1IPIHomo_sapiens(9606)Component
GO:0071144part_of heteromeric SMAD protein complex2IBA,IPIHomo_sapiens(9606)Component
GO:0071407involved_in cellular response to organic cyclic compound1IEAHomo_sapiens(9606)Process
GO:1901522involved_in positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus1ISSHomo_sapiens(9606)Process
GO:1902895involved_in positive regulation of miRNA transcription1IEAHomo_sapiens(9606)Process
GO:1903672involved_in positive regulation of sprouting angiogenesis1IMPHomo_sapiens(9606)Process

Expression