RBP Type	Non-canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Transmemebrane
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000170348	Gene ID	10972	Accession	16998
Symbol	TMED10	Alias	p23;TMP21;p24d1;S31I125;Tmp-21-I;S31III125;P24(DELTA)	Full Name	transmembrane p24 trafficking protein 10
Status	Confidence	Length	45144 bases	Strand	Minus strand
Position	14 : 75131469 - 75176612	RNA binding domain	N.A.
Summary	This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]