Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43SARS-COV-2VEEV
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_02_100 DataSet_02_101 DataSet_02_102 DataSet_02_103

Description

Ensembl ID ENSG00000169714 Gene ID 7555 Accession 13164
Symbol CNBP Alias DM2;ZNF9;CNBP1;PROMM;RNF163;ZCCHC22 Full Name CCHC-type zinc finger nucleic acid binding protein
Status Confidence Length 16096 bases Strand Minus strand
Position 3 : 129167827 - 129183922 RNA binding domain zf-CCHC
Summary This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000426223 zf-CCHC PF00098 3.7e-52 1
ENSP00000426223 zf-CCHC PF00098 3.7e-52 2
ENSP00000426223 zf-CCHC PF00098 3.7e-52 3
ENSP00000426223 zf-CCHC PF00098 3.7e-52 4
ENSP00000426223 zf-CCHC PF00098 3.7e-52 5
ENSP00000426223 zf-CCHC PF00098 3.7e-52 6
ENSP00000426223 zf-CCHC PF00098 3.7e-52 7
ENSP00000422110 zf-CCHC PF00098 5.5e-52 1
ENSP00000422110 zf-CCHC PF00098 5.5e-52 2
ENSP00000422110 zf-CCHC PF00098 5.5e-52 3
ENSP00000422110 zf-CCHC PF00098 5.5e-52 4
ENSP00000422110 zf-CCHC PF00098 5.5e-52 5
ENSP00000422110 zf-CCHC PF00098 5.5e-52 6
ENSP00000422110 zf-CCHC PF00098 5.5e-52 7
ENSP00000421323 zf-CCHC PF00098 6.6e-52 1
ENSP00000421323 zf-CCHC PF00098 6.6e-52 2
ENSP00000421323 zf-CCHC PF00098 6.6e-52 3
ENSP00000421323 zf-CCHC PF00098 6.6e-52 4
ENSP00000421323 zf-CCHC PF00098 6.6e-52 5
ENSP00000421323 zf-CCHC PF00098 6.6e-52 6
ENSP00000421323 zf-CCHC PF00098 6.6e-52 7
ENSP00000400444 zf-CCHC PF00098 9e-52 1
ENSP00000400444 zf-CCHC PF00098 9e-52 2
ENSP00000400444 zf-CCHC PF00098 9e-52 3
ENSP00000400444 zf-CCHC PF00098 9e-52 4
ENSP00000400444 zf-CCHC PF00098 9e-52 5
ENSP00000400444 zf-CCHC PF00098 9e-52 6
ENSP00000400444 zf-CCHC PF00098 9e-52 7
ENSP00000410619 zf-CCHC PF00098 9.5e-52 1
ENSP00000410619 zf-CCHC PF00098 9.5e-52 2
ENSP00000410619 zf-CCHC PF00098 9.5e-52 3
ENSP00000410619 zf-CCHC PF00098 9.5e-52 4
ENSP00000410619 zf-CCHC PF00098 9.5e-52 5
ENSP00000410619 zf-CCHC PF00098 9.5e-52 6
ENSP00000410619 zf-CCHC PF00098 9.5e-52 7
ENSP00000399488 zf-CCHC PF00098 1.2e-51 1
ENSP00000399488 zf-CCHC PF00098 1.2e-51 2
ENSP00000399488 zf-CCHC PF00098 1.2e-51 3
ENSP00000399488 zf-CCHC PF00098 1.2e-51 4
ENSP00000399488 zf-CCHC PF00098 1.2e-51 5
ENSP00000399488 zf-CCHC PF00098 1.2e-51 6
ENSP00000399488 zf-CCHC PF00098 1.2e-51 7
ENSP00000410769 zf-CCHC PF00098 1.3e-51 1
ENSP00000410769 zf-CCHC PF00098 1.3e-51 2
ENSP00000410769 zf-CCHC PF00098 1.3e-51 3
ENSP00000410769 zf-CCHC PF00098 1.3e-51 4
ENSP00000410769 zf-CCHC PF00098 1.3e-51 5
ENSP00000410769 zf-CCHC PF00098 1.3e-51 6
ENSP00000410769 zf-CCHC PF00098 1.3e-51 7
ENSP00000424787 zf-CCHC PF00098 6.3e-16 1
ENSP00000424787 zf-CCHC PF00098 6.3e-16 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
34362795 N6 -methyladenosine-Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression. Junge Deng 2021-10-15 Cancer research
37063799 Transcriptome-wide identification of single-stranded RNA binding proteins. Ruiqi Zhao 2023-04-12 Chemical science
30754726 Polyamine Metabolism as a Therapeutic Target inHedgehog-Driven Basal Cell Carcinomaand Medulloblastoma. Sonia Coni 2019-02-11 Cells
35011584 Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression. Noof Aloufi 2021-12-22 Cells
31219592 CNBP controls transcription by unfolding DNA G-quadruplex structures. P Aldana David 2019-09-05 Nucleic acids research
23285195 Yeast Gis2 and its human ortholog CNBP are novel components of stress-induced RNP granules. Marta Rojas 2012-01-01 PloS one
35909906 CircFMN2 Boosts Sorafenib Resistance in Hepatocellular Carcinoma Cells via Upregulating CNBP by Restraining Ubiquitination. Chen Fan 2022-01-01 Journal of oncology
26217220 Muscle wasting in myotonic dystrophies: a model of premature aging. Judith Alba Mateos-Aierdi 2015-01-01 Frontiers in aging neuroscience
26460945 Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth. Davide D'Amico 2015-10-12 Developmental cell
24726729 Arginine methylation of the cellular nucleic acid binding protein does not affect its subcellular localization but impedes RNA binding. Hung-Ming Wei 2014-05-02 FEBS letters
35205411 Myotonic Dystrophies: A Genetic Overview. Payam Soltanzadeh 2022-02-17 Genes
31919376 Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution. Nam Doo Kim 2020-01-09 Nature communications
35169159 E2F1-induced lncRNA, EMSLR regulates lncRNA LncPRESS1. Priyanka Priyanka 2022-02-15 Scientific reports
29199958 LAST, a c-Myc-inducible long noncoding RNA, cooperates with CNBP to promote CCND1 mRNA stability in human cells. Limian Cao 2017-12-04 eLife
36591216 Can G-quadruplex become a promising target in HBV therapy? Ye Teng 2022-01-01 Frontiers in immunology
35497433 Upregulation of lncRNA SUMO1P3 promotes proliferation, invasion and drug resistance in gastric cancer through interacting with the CNBP protein. Yinmou Guo 2020-02-04 RSC advances
27956239 RNAcompete methodology and application to determine sequence preferences of unconventional RNA-binding proteins. Debashish Ray 2017-04-15 Methods (San Diego, Calif.)
33264409 Properties and biological impact of RNA G-quadruplexes: from order to turmoil and back. Prakash Kharel 2020-12-16 Nucleic acids research
30384847 omniCLIP: probabilistic identification of protein-RNA interactions from CLIP-seq data. Philipp Drewe-Boss 2018-11-01 Genome biology
37251408 Molecular mechanisms and cellular functions of liquid-liquid phase separation during antiviral immune responses. Shuai Yang 2023-01-01 Frontiers in immunology
31981476 A Toxic RNA Catalyzes the Cellular Synthesis of Its Own Inhibitor, Shunting It to Endogenous Decay Pathways. I Raphael Benhamou 2020-02-20 Cell chemical biology
35436552 Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs. Stephanie Seneff 2022-06-01 Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
33349665 The SARS-CoV-2 RNA-protein interactome in infected human cells. Nora Schmidt 2021-03-01 Nature microbiology
33807682 CNBP Binds and Unfolds In Vitro G-Quadruplexes Formed in the SARS-CoV-2 Positive and Negative Genome Strands. Georgina Bezzi 2021-03-05 International journal of molecular sciences
32975549 Small molecule recognition of disease-relevant RNA structures. M Samantha Meyer 2020-10-05 Chemical Society reviews
34517941 Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function. Sonia Coni 2021-09-14 eLife
33367597 Structure and regulation of coronavirus genomes: state-of-the-art and novel insights from SARS-CoV-2 studies. Ilaria Manfredonia 2021-02-26 Biochemical Society transactions
28329689 The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation. Daniel Benhalevy 2017-03-21 Cell reports
35343064 RNA-protein interactomes as invaluable resources to study RNA viruses: Insights from SARS CoV-2 studies. Marcin Koliński 2022-11-01 Wiley interdisciplinary reviews. RNA

Transcripts

Name Transcript ID bp Protein Translation ID
CNBP-207 ENST00000502976 1626 170aa ENSP00000421323
CNBP-201 ENST00000422453 3295 177aa ENSP00000410619
CNBP-204 ENST00000451728 1641 178aa ENSP00000399488
CNBP-203 ENST00000446936 1623 172aa ENSP00000400444
CNBP-205 ENST00000500450 1516 160aa ENSP00000426223
CNBP-208 ENST00000504813 1549 167aa ENSP00000422110
CNBP-202 ENST00000441626 1040 179aa ENSP00000410769
CNBP-206 ENST00000502372 1026 No protein -
CNBP-210 ENST00000512338 502 113aa ENSP00000424787
CNBP-209 ENST00000507573 641 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000169714homo_sapiensENSP0000034563368.072360.8434homo_sapiensENSP0000041061963.841857.0621
ENSG00000169714homo_sapiensENSP0000038504721.033214.7601homo_sapiensENSP0000041061932.203422.5989
ENSG00000169714homo_sapiensENSP0000033783913.6288.47145homo_sapiensENSP0000041061941.807925.9887

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000169714homo_sapiensENSP0000041061997.175197.1751nomascus_leucogenysENSNLEP0000002855996.629296.6292
ENSG00000169714homo_sapiensENSP00000410619100100pan_paniscusENSPPAP0000000968882.325682.3256
ENSG00000169714homo_sapiensENSP00000410619100100pongo_abeliiENSPPYP00000015013100100
ENSG00000169714homo_sapiensENSP0000041061997.175197.1751pan_troglodytesENSPTRP0000007973096.629296.6292
ENSG00000169714homo_sapiensENSP0000041061997.175197.1751gorilla_gorillaENSGGOP0000003625496.629296.6292
ENSG00000169714homo_sapiensENSP0000041061997.740197.7401ornithorhynchus_anatinusENSOANP0000004373397.740197.7401
ENSG00000169714homo_sapiensENSP0000041061999.43599.435sarcophilus_harrisiiENSSHAP0000002279099.43599.435
ENSG00000169714homo_sapiensENSP0000041061999.43599.435notamacropus_eugeniiENSMEUP0000001065599.43599.435
ENSG00000169714homo_sapiensENSP0000041061975.141275.1412choloepus_hoffmanniENSCHOP0000000078898.518598.5185
ENSG00000169714homo_sapiensENSP00000410619100100dasypus_novemcinctusENSDNOP00000019523100100
ENSG00000169714homo_sapiensENSP00000410619100100echinops_telfairiENSETEP00000006833100100
ENSG00000169714homo_sapiensENSP0000041061986.440781.9209echinops_telfairiENSETEP0000000159987.428682.8571
ENSG00000169714homo_sapiensENSP0000041061993.220392.0904callithrix_jacchusENSCJAP0000008639890.659389.5604
ENSG00000169714homo_sapiensENSP00000410619100100cercocebus_atysENSCATP00000006429100100
ENSG00000169714homo_sapiensENSP00000410619100100macaca_fascicularisENSMFAP00000046285100100
ENSG00000169714homo_sapiensENSP00000410619100100macaca_mulattaENSMMUP00000068989100100
ENSG00000169714homo_sapiensENSP00000410619100100macaca_nemestrinaENSMNEP00000007823100100
ENSG00000169714homo_sapiensENSP00000410619100100papio_anubisENSPANP00000003453100100
ENSG00000169714homo_sapiensENSP00000410619100100mandrillus_leucophaeusENSMLEP00000035515100100
ENSG00000169714homo_sapiensENSP00000410619100100tursiops_truncatusENSTTRP00000014470100100
ENSG00000169714homo_sapiensENSP00000410619100100vulpes_vulpesENSVVUP00000024950100100
ENSG00000169714homo_sapiensENSP0000041061985.875784.1808vulpes_vulpesENSVVUP0000000418284.916283.2402
ENSG00000169714homo_sapiensENSP00000410619100100mus_spretusMGP_SPRETEiJ_P007784199.438299.4382
ENSG00000169714homo_sapiensENSP0000041061910099.435equus_asinusENSEASP0000502321298.882798.324
ENSG00000169714homo_sapiensENSP0000041061987.005785.8757capra_hircusENSCHIP0000002694492.771191.5663
ENSG00000169714homo_sapiensENSP00000410619100100loxodonta_africanaENSLAFP00000002091100100
ENSG00000169714homo_sapiensENSP00000410619100100panthera_leoENSPLOP00000004968100100
ENSG00000169714homo_sapiensENSP0000041061970.621563.2768ailuropoda_melanoleucaENSAMEP0000004071859.523853.3333
ENSG00000169714homo_sapiensENSP0000041061970.621563.2768ailuropoda_melanoleucaENSAMEP0000002644259.523853.3333
ENSG00000169714homo_sapiensENSP00000410619100100bos_indicus_hybridENSBIXP0000504513578.666778.6667
ENSG00000169714homo_sapiensENSP0000041061990.395590.3955oryctolagus_cuniculusENSOCUP0000003851299.378999.3789
ENSG00000169714homo_sapiensENSP00000410619100100oryctolagus_cuniculusENSOCUP00000030061100100
ENSG00000169714homo_sapiensENSP0000041061996.045295.4802equus_caballusENSECAP0000000748198.837298.2558
ENSG00000169714homo_sapiensENSP00000410619100100canis_lupus_familiarisENSCAFP00845028250100100
ENSG00000169714homo_sapiensENSP00000410619100100panthera_pardusENSPPRP0000000871299.438299.4382
ENSG00000169714homo_sapiensENSP00000410619100100marmota_marmota_marmotaENSMMMP00000025221100100
ENSG00000169714homo_sapiensENSP00000410619100100balaenoptera_musculusENSBMSP00010017020100100
ENSG00000169714homo_sapiensENSP00000410619100100cavia_porcellusENSCPOP00000023678100100
ENSG00000169714homo_sapiensENSP00000410619100100felis_catusENSFCAP00000042207100100
ENSG00000169714homo_sapiensENSP00000410619100100ursus_americanusENSUAMP0000002426899.438299.4382
ENSG00000169714homo_sapiensENSP0000041061999.43599.435monodelphis_domesticaENSMODP0000003981799.43599.435
ENSG00000169714homo_sapiensENSP00000410619100100bison_bison_bisonENSBBBP00000006606100100
ENSG00000169714homo_sapiensENSP00000410619100100monodon_monocerosENSMMNP00015018076100100
ENSG00000169714homo_sapiensENSP0000041061994.350394.3503sus_scrofaENSSSCP00000052646100100
ENSG00000169714homo_sapiensENSP00000410619100100microcebus_murinusENSMICP0000004974899.438299.4382
ENSG00000169714homo_sapiensENSP0000041061968.361664.4068octodon_degusENSODEP0000000267684.027879.1667
ENSG00000169714homo_sapiensENSP0000041061976.271273.4463jaculus_jaculusENSJJAP0000001542090.60487.2483
ENSG00000169714homo_sapiensENSP0000041061988.135686.4407jaculus_jaculusENSJJAP0000000139363.414662.1951
ENSG00000169714homo_sapiensENSP0000041061995.480295.4802jaculus_jaculusENSJJAP0000000588899.411899.4118
ENSG00000169714homo_sapiensENSP0000041061995.480295.4802ovis_aries_rambouilletENSOARP0002002089399.411899.4118
ENSG00000169714homo_sapiensENSP0000041061949.717543.5028ursus_maritimusENSUMAP0000003176570.967762.0968
ENSG00000169714homo_sapiensENSP00000410619100100ochotona_princepsENSOPRP00000005024100100
ENSG00000169714homo_sapiensENSP00000410619100100delphinapterus_leucasENSDLEP00000014015100100
ENSG00000169714homo_sapiensENSP00000410619100100physeter_catodonENSPCTP00005030240100100
ENSG00000169714homo_sapiensENSP0000041061999.43599.435mus_caroliMGP_CAROLIEiJ_P007486398.876498.8764
ENSG00000169714homo_sapiensENSP00000410619100100mus_musculusENSMUSP0000003213899.438299.4382
ENSG00000169714homo_sapiensENSP00000410619100100dipodomys_ordiiENSDORP0000000273999.438299.4382
ENSG00000169714homo_sapiensENSP00000410619100100mustela_putorius_furoENSMPUP00000017205100100
ENSG00000169714homo_sapiensENSP0000041061974.576373.4463aotus_nancymaaeENSANAP0000000279384.615483.3333
ENSG00000169714homo_sapiensENSP00000410619100100aotus_nancymaaeENSANAP0000002565999.438299.4382
ENSG00000169714homo_sapiensENSP00000410619100100saimiri_boliviensis_boliviensisENSSBOP00000013961100100
ENSG00000169714homo_sapiensENSP0000041061910098.8701vicugna_pacosENSVPAP0000000664110098.8701
ENSG00000169714homo_sapiensENSP00000410619100100chlorocebus_sabaeusENSCSAP00000005074100100
ENSG00000169714homo_sapiensENSP0000041061996.045296.0452tupaia_belangeriENSTBEP0000001092296.045296.0452
ENSG00000169714homo_sapiensENSP00000410619100100mesocricetus_auratusENSMAUP00000011176100100
ENSG00000169714homo_sapiensENSP0000041061991.525491.5254mesocricetus_auratusENSMAUP0000001789294.736894.7368
ENSG00000169714homo_sapiensENSP00000410619100100phocoena_sinusENSPSNP00000031507100100
ENSG00000169714homo_sapiensENSP0000041061910098.8701camelus_dromedariusENSCDRP0000501423610098.8701
ENSG00000169714homo_sapiensENSP00000410619100100carlito_syrichtaENSTSYP00000003974100100
ENSG00000169714homo_sapiensENSP00000410619100100panthera_tigris_altaicaENSPTIP00000020465100100
ENSG00000169714homo_sapiensENSP00000410619100100rattus_norvegicusENSRNOP0000001388499.438299.4382
ENSG00000169714homo_sapiensENSP00000410619100100prolemur_simusENSPSMP00000009456100100
ENSG00000169714homo_sapiensENSP0000041061996.045296.0452microtus_ochrogasterENSMOCP00000002593100100
ENSG00000169714homo_sapiensENSP00000410619100100sorex_araneusENSSARP00000010717100100
ENSG00000169714homo_sapiensENSP00000410619100100peromyscus_maniculatus_bairdiiENSPEMP00000028831100100
ENSG00000169714homo_sapiensENSP00000410619100100bos_mutusENSBMUP00000018681100100
ENSG00000169714homo_sapiensENSP00000410619100100mus_spicilegusENSMSIP00000016140100100
ENSG00000169714homo_sapiensENSP00000410619100100cricetulus_griseus_chok1gshdENSCGRP00001001206100100
ENSG00000169714homo_sapiensENSP0000041061989.265588.7006cricetulus_griseus_chok1gshdENSCGRP0000101372191.860591.2791
ENSG00000169714homo_sapiensENSP0000041061999.43599.435pteropus_vampyrusENSPVAP0000001420498.876498.8764
ENSG00000169714homo_sapiensENSP00000410619100100myotis_lucifugusENSMLUP0000001142397.252797.2527
ENSG00000169714homo_sapiensENSP0000041061996.045296.0452vombatus_ursinusENSVURP00010021806100100
ENSG00000169714homo_sapiensENSP0000041061910099.435rhinolophus_ferrumequinumENSRFEP0001000872810099.435
ENSG00000169714homo_sapiensENSP00000410619100100neovison_visonENSNVIP00000025299100100
ENSG00000169714homo_sapiensENSP0000041061996.045296.0452bos_taurusENSBTAP00000016130100100
ENSG00000169714homo_sapiensENSP0000041061978.531176.8362heterocephalus_glaber_femaleENSHGLP0000006038578.089976.4045
ENSG00000169714homo_sapiensENSP00000410619100100rhinopithecus_bietiENSRBIP00000012781100100
ENSG00000169714homo_sapiensENSP00000410619100100canis_lupus_dingoENSCAFP00020005957100100
ENSG00000169714homo_sapiensENSP00000410619100100sciurus_vulgarisENSSVLP00005025093100100
ENSG00000169714homo_sapiensENSP00000410619100100sciurus_vulgarisENSSVLP00005015525100100
ENSG00000169714homo_sapiensENSP0000041061999.43599.435phascolarctos_cinereusENSPCIP0000000053099.43599.435
ENSG00000169714homo_sapiensENSP00000410619100100procavia_capensisENSPCAP00000010766100100
ENSG00000169714homo_sapiensENSP00000410619100100nannospalax_galiliENSNGAP00000004058100100
ENSG00000169714homo_sapiensENSP00000410619100100bos_grunniensENSBGRP0000002225792.670292.6702
ENSG00000169714homo_sapiensENSP00000410619100100chinchilla_lanigeraENSCLAP00000013308100100
ENSG00000169714homo_sapiensENSP0000041061999.43599.435cervus_hanglu_yarkandensisENSCHYP0000002908299.43599.435
ENSG00000169714homo_sapiensENSP00000410619100100catagonus_wagneriENSCWAP00000025200100100
ENSG00000169714homo_sapiensENSP00000410619100100ictidomys_tridecemlineatusENSSTOP00000000151100100
ENSG00000169714homo_sapiensENSP00000410619100100otolemur_garnettiiENSOGAP0000002200299.438299.4382
ENSG00000169714homo_sapiensENSP00000410619100100cebus_imitatorENSCCAP00000032052100100
ENSG00000169714homo_sapiensENSP00000410619100100urocitellus_parryiiENSUPAP0001000554496.195796.1957
ENSG00000169714homo_sapiensENSP0000041061985.310784.1808moschus_moschiferusENSMMSP0000003166974.752573.7624
ENSG00000169714homo_sapiensENSP00000410619100100rhinopithecus_roxellanaENSRROP00000045110100100
ENSG00000169714homo_sapiensENSP00000410619100100mus_pahariMGP_PahariEiJ_P005099499.438299.4382
ENSG00000169714homo_sapiensENSP0000041061941.242931.0734caenorhabditis_elegansK08D12.3a.148.344436.4238
ENSG00000169714homo_sapiensENSP0000041061948.022636.7232drosophila_melanogasterFBpp007190351.515239.3939
ENSG00000169714homo_sapiensENSP0000041061957.062146.3277ciona_intestinalisENSCINP0000003227162.732950.9317
ENSG00000169714homo_sapiensENSP0000041061939.54830.5085petromyzon_marinusENSPMAP0000001034766.037750.9434
ENSG00000169714homo_sapiensENSP0000041061953.107344.0678petromyzon_marinusENSPMAP0000000372370.676758.6466
ENSG00000169714homo_sapiensENSP0000041061979.66170.6215eptatretus_burgeriENSEBUP0000000294070.149362.1891
ENSG00000169714homo_sapiensENSP0000041061990.960487.5706callorhinchus_miliiENSCMIP0000002472596.407292.8144
ENSG00000169714homo_sapiensENSP0000041061985.875782.4859latimeria_chalumnaeENSLACP0000000600093.251589.5705
ENSG00000169714homo_sapiensENSP0000041061993.220388.1356lepisosteus_oculatusENSLOCP0000001723894.285789.1429
ENSG00000169714homo_sapiensENSP0000041061976.271267.7966clupea_harengusENSCHAP0000003170482.317173.1707
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266clupea_harengusENSCHAP000000424957566.3043
ENSG00000169714homo_sapiensENSP0000041061977.966169.4915danio_rerioENSDARP0000009529385.714376.3975
ENSG00000169714homo_sapiensENSP0000041061977.401167.2316danio_rerioENSDARP0000006729284.049173.0061
ENSG00000169714homo_sapiensENSP0000041061976.271267.2316carassius_auratusENSCARP0000008422782.822173.0061
ENSG00000169714homo_sapiensENSP0000041061977.966166.6667carassius_auratusENSCARP0000009720181.656869.8225
ENSG00000169714homo_sapiensENSP0000041061977.401168.3616carassius_auratusENSCARP0000005347484.049174.2331
ENSG00000169714homo_sapiensENSP0000041061964.971757.0621carassius_auratusENSCARP0000005553680.985971.1268
ENSG00000169714homo_sapiensENSP0000041061976.836268.9266astyanax_mexicanusENSAMXP0000002998779.069870.9302
ENSG00000169714homo_sapiensENSP0000041061977.966170.0565astyanax_mexicanusENSAMXP0000000556285.714377.0186
ENSG00000169714homo_sapiensENSP0000041061977.401168.9266ictalurus_punctatusENSIPUP0000001680885.093275.7764
ENSG00000169714homo_sapiensENSP0000041061966.666757.0621ictalurus_punctatusENSIPUP0000002787563.783854.5946
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266esox_luciusENSELUP0000006292984.146374.3902
ENSG00000169714homo_sapiensENSP0000041061977.966170.0565esox_luciusENSELUP0000001324584.662676.0736
ENSG00000169714homo_sapiensENSP0000041061977.966170.0565electrophorus_electricusENSEEEP0000001650384.146375.6098
ENSG00000169714homo_sapiensENSP0000041061977.401169.4915electrophorus_electricusENSEEEP0000001935584.049175.4601
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266oncorhynchus_kisutchENSOKIP0000503763382.634773.0539
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266oncorhynchus_kisutchENSOKIP0000501175784.146374.3902
ENSG00000169714homo_sapiensENSP0000041061977.401170.0565oncorhynchus_kisutchENSOKIP0000506551775.274768.1319
ENSG00000169714homo_sapiensENSP0000041061977.966170.0565oncorhynchus_kisutchENSOKIP0000500075384.662676.0736
ENSG00000169714homo_sapiensENSP0000041061977.966170.0565oncorhynchus_mykissENSOMYP0000014298884.662676.0736
ENSG00000169714homo_sapiensENSP0000041061977.966170.0565oncorhynchus_mykissENSOMYP0000001284384.662676.0736
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266oncorhynchus_mykissENSOMYP0000006419682.634773.0539
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266oncorhynchus_mykissENSOMYP0000007989183.636473.9394
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266salmo_salarENSSSAP0000001668176.666767.7778
ENSG00000169714homo_sapiensENSP0000041061977.401168.9266salmo_salarENSSSAP0000017639874.054165.9459
ENSG00000169714homo_sapiensENSP0000041061977.966170.0565salmo_truttaENSSTUP0000000589584.662676.0736
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266salmo_truttaENSSTUP0000001110682.634773.0539
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266salmo_truttaENSSTUP0000004429084.146374.3902
ENSG00000169714homo_sapiensENSP0000041061978.531170.0565salmo_truttaENSSTUP0000007919385.276176.0736
ENSG00000169714homo_sapiensENSP0000041061976.836264.9717gadus_morhuaENSGMOP0000005843473.91362.5
ENSG00000169714homo_sapiensENSP0000041061959.88750.2825gadus_morhuaENSGMOP0000001826170.198758.9404
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316fundulus_heteroclitusENSFHEP0000000218981.927771.6867
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316poecilia_reticulataENSPREP0000001221681.927771.6867
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316xiphophorus_maculatusENSXMAP0000003886881.927771.6867
ENSG00000169714homo_sapiensENSP0000041061976.271267.2316oryzias_latipesENSORLP0000001434481.325371.6867
ENSG00000169714homo_sapiensENSP0000041061970.056553.1073cyclopterus_lumpusENSCLMP0000500715667.759651.3661
ENSG00000169714homo_sapiensENSP0000041061974.576363.8418cyclopterus_lumpusENSCLMP0000503849878.106566.8639
ENSG00000169714homo_sapiensENSP0000041061945.197731.6384oreochromis_niloticusENSONIP0000002978039.408927.5862
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966oreochromis_niloticusENSONIP0000002914481.927772.2892
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316oreochromis_niloticusENSONIP0000007506074.725365.3846
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966haplochromis_burtoniENSHBUP0000001943281.927772.2892
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266haplochromis_burtoniENSHBUP0000003278585.714375.7764
ENSG00000169714homo_sapiensENSP0000041061957.627148.0226astatotilapia_callipteraENSACLP0000001011963.7553.125
ENSG00000169714homo_sapiensENSP0000041061947.457635.0282astatotilapia_callipteraENSACLP0000002345248.837236.0465
ENSG00000169714homo_sapiensENSP0000041061947.457634.4633astatotilapia_callipteraENSACLP0000001659050.909136.9697
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266astatotilapia_callipteraENSACLP0000002118485.714375.7764
ENSG00000169714homo_sapiensENSP0000041061971.186461.0169sparus_aurataENSSAUP0001003198574.117663.5294
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966lates_calcariferENSLCAP0001004143281.927772.2892
ENSG00000169714homo_sapiensENSP0000041061975.141266.1017lates_calcariferENSLCAP0001005011580.120570.4819
ENSG00000169714homo_sapiensENSP0000041061994.915392.0904xenopus_tropicalisENSXETP0000010244598.823595.8824
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503chrysemys_picta_belliiENSCPBP0000003803698.830497.6608
ENSG00000169714homo_sapiensENSP0000041061994.915393.7853sphenodon_punctatusENSSPUP0000002356298.823597.6471
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503crocodylus_porosusENSCPRP0000502767998.830497.6608
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503laticauda_laticaudataENSLLTP0000001242198.830497.6608
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503notechis_scutatusENSNSUP0000002823398.830497.6608
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503pseudonaja_textilisENSPTXP0000000991198.830497.6608
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503anas_platyrhynchos_platyrhynchosENSAPLP0000001406099.411898.2353
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503gallus_gallusENSGALP0001004145398.830497.6608
ENSG00000169714homo_sapiensENSP0000041061997.175196.0452meleagris_gallopavoENSMGAP0000002339095.027693.9227
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503serinus_canariaENSSCAP0000001507299.411898.2353
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503parus_majorENSPMJP0000000589398.830497.6608
ENSG00000169714homo_sapiensENSP0000041061995.480293.7853anolis_carolinensisENSACAP0000002586098.830497.076
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966neolamprologus_brichardiENSNBRP0000002901681.927772.2892
ENSG00000169714homo_sapiensENSP0000041061979.09669.4915neolamprologus_brichardiENSNBRP0000000895282.352972.3529
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503naja_najaENSNNAP0000002781098.830497.6608
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503podarcis_muralisENSPMRP0000001949798.830497.6608
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503geospiza_fortisENSGFOP0000001522099.411898.2353
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503taeniopygia_guttataENSTGUP0000000411599.411898.2353
ENSG00000169714homo_sapiensENSP0000041061990.960485.3107erpetoichthys_calabaricusENSECRP0000003060795.266389.3491
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316kryptolebias_marmoratusENSKMAP0000001846781.927771.6867
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503salvator_merianaeENSSMRP0000002530898.830497.6608
ENSG00000169714homo_sapiensENSP0000041061975.706266.1017oryzias_javanicusENSOJAP0000002216281.212170.9091
ENSG00000169714homo_sapiensENSP0000041061979.09669.4915amphilophus_citrinellusENSACIP0000001893986.956576.3975
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966amphilophus_citrinellusENSACIP0000000462481.927772.2892
ENSG00000169714homo_sapiensENSP0000041061975.141265.5367dicentrarchus_labraxENSDLAP0000507196381.595171.1656
ENSG00000169714homo_sapiensENSP0000041061976.836268.3616amphiprion_perculaENSAPEP0000002021781.437172.4551
ENSG00000169714homo_sapiensENSP0000041061976.271267.2316oryzias_sinensisENSOSIP0000000060881.325371.6867
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503pelodiscus_sinensisENSPSIP0000001058498.830497.6608
ENSG00000169714homo_sapiensENSP0000041061998.870197.7401gopherus_evgoodeiENSGEVP0000502548598.870197.7401
ENSG00000169714homo_sapiensENSP0000041061949.152546.3277chelonoidis_abingdoniiENSCABP0000000611393.548488.172
ENSG00000169714homo_sapiensENSP0000041061978.531168.3616seriola_dumeriliENSSDUP0000002517684.242473.3333
ENSG00000169714homo_sapiensENSP0000041061976.271267.2316seriola_dumeriliENSSDUP0000000041082.317172.561
ENSG00000169714homo_sapiensENSP0000041061975.706262.1469cottoperca_gobioENSCGOP0000004338582.71667.9012
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503struthio_camelus_australisENSSCUP0000002053898.830497.6608
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503anser_brachyrhynchusENSABRP0000001077098.830497.6608
ENSG00000169714homo_sapiensENSP0000041061974.011362.1469gasterosteus_aculeatusENSGACP0000000007977.058864.7059
ENSG00000169714homo_sapiensENSP0000041061974.011363.2768cynoglossus_semilaevisENSCSEP0000003339280.368168.7117
ENSG00000169714homo_sapiensENSP0000041061975.706263.8418cynoglossus_semilaevisENSCSEP0000003180575.280963.4831
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316poecilia_formosaENSPFOP0000001601481.927771.6867
ENSG00000169714homo_sapiensENSP0000041061974.576362.1469myripristis_murdjanENSMMDP0000503901281.987668.323
ENSG00000169714homo_sapiensENSP0000041061977.966170.0565myripristis_murdjanENSMMDP0000502762084.662676.0736
ENSG00000169714homo_sapiensENSP0000041061976.271265.5367sander_luciopercaENSSLUP0000000491881.325369.8795
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503strigops_habroptilaENSSHBP0000500905799.411898.2353
ENSG00000169714homo_sapiensENSP0000041061976.836268.3616amphiprion_ocellarisENSAOCP0000002196681.437172.4551
ENSG00000169714homo_sapiensENSP0000041061998.870197.7401terrapene_carolina_triunguisENSTMTP0000002122798.314697.191
ENSG00000169714homo_sapiensENSP0000041061941.242938.4181hucho_huchoENSHHUP0000003450287.951881.9277
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266hucho_huchoENSHHUP0000004273884.146374.3902
ENSG00000169714homo_sapiensENSP0000041061961.016954.2373hucho_huchoENSHHUP0000007382174.482866.2069
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266hucho_huchoENSHHUP0000002389368.656760.6965
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966betta_splendensENSBSLP0000002259281.927772.2892
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316betta_splendensENSBSLP0000000744282.926872.561
ENSG00000169714homo_sapiensENSP0000041061977.966169.4915pygocentrus_nattereriENSPNAP0000000139985.714376.3975
ENSG00000169714homo_sapiensENSP0000041061977.401169.4915pygocentrus_nattereriENSPNAP0000003365384.049175.4601
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966anabas_testudineusENSATEP0000002228281.927772.2892
ENSG00000169714homo_sapiensENSP0000041061978.531169.4915anabas_testudineusENSATEP0000001360581.764772.3529
ENSG00000169714homo_sapiensENSP0000041061962.711949.1525ciona_savignyiENSCSAVP0000000237042.366433.2061
ENSG00000169714homo_sapiensENSP0000041061948.587632.7684saccharomyces_cerevisiaeYNL255C56.209237.9085
ENSG00000169714homo_sapiensENSP0000041061976.271267.2316seriola_lalandi_dorsalisENSSLDP0000001467782.317172.561
ENSG00000169714homo_sapiensENSP0000041061978.531168.9266seriola_lalandi_dorsalisENSSLDP0000002877586.335475.7764
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966pundamilia_nyerereiENSPNYP0000000651181.927772.2892
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266pundamilia_nyerereiENSPNYP0000001968785.714375.7764
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966mastacembelus_armatusENSMAMP0000003590481.927772.2892
ENSG00000169714homo_sapiensENSP0000041061978.531168.9266mastacembelus_armatusENSMAMP0000001423084.756174.3902
ENSG00000169714homo_sapiensENSP0000041061976.836268.3616stegastes_partitusENSSPAP0000002617281.437172.4551
ENSG00000169714homo_sapiensENSP0000041061959.88748.5876stegastes_partitusENSSPAP0000002907776.811662.3188
ENSG00000169714homo_sapiensENSP0000041061943.502838.9831oncorhynchus_tshawytschaENSOTSP0000506837280.208371.875
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266oncorhynchus_tshawytschaENSOTSP0000502517284.146374.3902
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266oncorhynchus_tshawytschaENSOTSP0000504596382.634773.0539
ENSG00000169714homo_sapiensENSP0000041061952.542447.4576oncorhynchus_tshawytschaENSOTSP0000508212257.76452.1739
ENSG00000169714homo_sapiensENSP0000041061976.836266.6667acanthochromis_polyacanthusENSAPOP0000000845681.927771.0843
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503aquila_chrysaetos_chrysaetosENSACCP0002001408699.411898.2353
ENSG00000169714homo_sapiensENSP0000041061976.271266.6667nothobranchius_furzeriENSNFUP0001505036181.325371.0843
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316cyprinodon_variegatusENSCVAP0000002691081.927771.6867
ENSG00000169714homo_sapiensENSP0000041061976.836268.9266denticeps_clupeoidesENSDCDP0000004402180.473472.1893
ENSG00000169714homo_sapiensENSP0000041061977.966171.1864denticeps_clupeoidesENSDCDP0000002110484.146376.8293
ENSG00000169714homo_sapiensENSP0000041061974.011363.2768larimichthys_croceaENSLCRP0000501547978.443167.0659
ENSG00000169714homo_sapiensENSP0000041061961.581952.5424takifugu_rubripesENSTRUP0000005613267.701957.764
ENSG00000169714homo_sapiensENSP0000041061995.480294.3503ficedula_albicollisENSFALP0000003218598.830497.6608
ENSG00000169714homo_sapiensENSP0000041061975.141266.1017hippocampus_comesENSHCOP0000000235879.640770.0599
ENSG00000169714homo_sapiensENSP0000041061972.316458.7571hippocampus_comesENSHCOP0000002496679.012364.1975
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966cyprinus_carpio_carpioENSCCRP0000012405377.714368.5714
ENSG00000169714homo_sapiensENSP0000041061971.751463.2768cyprinus_carpio_carpioENSCCRP0000005253783.552673.6842
ENSG00000169714homo_sapiensENSP0000041061974.576363.2768cyprinus_carpio_carpioENSCCRP0000003984769.841359.2593
ENSG00000169714homo_sapiensENSP0000041061968.361661.0169cyprinus_carpio_carpioENSCCRP0000015405469.942262.4277
ENSG00000169714homo_sapiensENSP0000041061995.480293.2203coturnix_japonicaENSCJPP0000501556099.411897.0588
ENSG00000169714homo_sapiensENSP0000041061976.836267.2316poecilia_latipinnaENSPLAP0000001594881.927771.6867
ENSG00000169714homo_sapiensENSP0000041061973.446363.8418sinocyclocheilus_grahamiENSSGRP0000002036980.745370.1863
ENSG00000169714homo_sapiensENSP0000041061977.966169.4915sinocyclocheilus_grahamiENSSGRP0000006943183.636474.5455
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966sinocyclocheilus_grahamiENSSGRP0000009446483.435673.6196
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966sinocyclocheilus_grahamiENSSGRP0000005313877.714368.5714
ENSG00000169714homo_sapiensENSP0000041061976.836267.7966maylandia_zebraENSMZEP0000503466581.927772.2892
ENSG00000169714homo_sapiensENSP0000041061977.966168.9266maylandia_zebraENSMZEP0000501601985.714375.7764
ENSG00000169714homo_sapiensENSP0000041061974.011361.0169tetraodon_nigroviridisENSTNIP0000002110178.443164.6707
ENSG00000169714homo_sapiensENSP0000041061977.401169.4915paramormyrops_kingsleyaeENSPKIP0000004072183.536675
ENSG00000169714homo_sapiensENSP0000041061978.531171.1864paramormyrops_kingsleyaeENSPKIP0000000951886.335478.2609
ENSG00000169714homo_sapiensENSP0000041061977.401168.9266scleropages_formosusENSSFOP0001504154783.536674.3902
ENSG00000169714homo_sapiensENSP0000041061978.531170.6215scleropages_formosusENSSFOP0001506547282.738174.4048
ENSG00000169714homo_sapiensENSP0000041061997.740196.0452leptobrachium_leishanenseENSLLEP0000004281197.740196.0452
ENSG00000169714homo_sapiensENSP0000041061961.016957.6271leptobrachium_leishanenseENSLLEP0000004291482.442777.8626
ENSG00000169714homo_sapiensENSP0000041061994.350392.6554leptobrachium_leishanenseENSLLEP0000001402698.235396.4706
ENSG00000169714homo_sapiensENSP0000041061974.576364.4068scophthalmus_maximusENSSMAP0000005952773.333363.3333
ENSG00000169714homo_sapiensENSP0000041061975.706266.6667scophthalmus_maximusENSSMAP0000001067883.229873.2919

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003727enables single-stranded RNA binding1IBAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634NOT located_in nucleus2ISSHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1ISSHomo_sapiens(9606)Component
GO:0005829located_in cytosol2ISS,TASHomo_sapiens(9606)Component
GO:0006355involved_in regulation of DNA-templated transcription1TASHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0008284involved_in positive regulation of cell population proliferation1ISSHomo_sapiens(9606)Process
GO:0042632involved_in cholesterol homeostasis1TASHomo_sapiens(9606)Process
GO:0045182enables translation regulator activity1IBAHomo_sapiens(9606)Function
GO:0045893involved_in positive regulation of DNA-templated transcription1ISSHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1ISSHomo_sapiens(9606)Process
GO:0051880enables G-quadruplex DNA binding1IDAHomo_sapiens(9606)Function
GO:0071919involved_in G-quadruplex DNA formation1IDAHomo_sapiens(9606)Process
GO:2000767involved_in positive regulation of cytoplasmic translation1IBAHomo_sapiens(9606)Process

Expression