Ensembl ID ENSG00000169714 Gene ID 7555 Accession 13164
Gene Symbol CNBP Alias DM2;ZNF9;CNBP1;PROMM;RNF163;ZCCHC22 Full Name CCHC-type zinc finger nucleic acid binding protein
Position 3 : 129167827 - 129183922 Length 16096 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]

ENSG00000169714 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000169714 CNBP 0.46 5.94e-11 LUSC
ENSG00000169714 CNBP -0.7 2.72e-32 LIHC
ENSG00000169714 CNBP -0.5 1.06e-14 UCEC
ENSG00000169714 CNBP -1.2 2.14e-16 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000169714 CNBP cervical cancer 16329995
ENSG00000169714 CNBP cancer 23774591
ENSG00000169714 CNBP tumor 24594223
ENSG00000169714 CNBP Lung Cancer 29722257
ENSG00000169714 CNBP tumor 30335765
ENSG00000169714 CNBP tumor 30360486
ENSG00000169714 CNBP tumor 31087358
ENSG00000169714 CNBP cancer 31219592
ENSG00000169714 CNBP gastric cancer 31718709
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000169714 CNBP colorectal adenocarcinoma sequence_alteration 0.8787% (10/1138) 1 entry
ENSG00000169714 CNBP chronic lymphocytic leukemia sequence_alteration 0.4505% (4/888) 1 entry
ENSG00000169714 CNBP lung adenocarcinoma missense_variant 0.258% (3/1163) 2 entries
ENSG00000169714 CNBP colorectal adenocarcinoma missense_variant 0.8787% (10/1138) 2 entries
ENSG00000169714 CNBP osteosarcoma frameshift_variant 0.8621% (1/116) 1 entry
ENSG00000169714 CNBP bile duct adenocarcinoma stop_gained 1.058% (2/189) 1 entry
ENSG00000169714 CNBP aneurysmal bone cyst gene_fusion 50.0% (1/2) 1 entry
ENSG00000169714 CNBP colon adenocarcinoma sequence_alteration 0.277% (2/722) 1 entry
ENSG00000169714 CNBP melanoma sequence_alteration 0.9901% (1/101) 1 entry
ENSG00000169714 CNBP hepatocellular carcinoma sequence_alteration 0.2225% (2/899) 1 entry
ENSG00000169714 CNBP hepatocellular carcinoma missense_variant 0.2225% (2/899) 1 entry
ENSG00000169714 CNBP small cell lung carcinoma missense_variant 0.3145% (1/318) 1 entry
ENSG00000169714 CNBP bile duct adenocarcinoma missense_variant 1.058% (2/189) 1 entry
ENSG00000169714 CNBP chronic lymphocytic leukemia stop_gained 0.4505% (4/888) 1 entry
ENSG00000169714 CNBP melanoma missense_variant 0.9901% (1/101) 1 entry
ENSG00000169714 CNBP cecum adenocarcinoma missense_variant 0.8% (1/125) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000169714 CNBP MESO 0.02 low
ENSG00000169714 CNBP UVM 0.00033 low
ENSG00000169714 CNBP PAAD 4e-04 high
ENSG00000169714 CNBP UCEC 0.013 low
ENSG00000169714 CNBP ACC 0.029 high
ENSG00000169714 CNBP LUSC 0.042 high
ENSG00000169714 CNBP KIRP 0.00011 high
ENSG00000169714 CNBP KICH 0.013 high
ENSG00000169714 CNBP PCPG 0.001 high
ENSG00000169714 CNBP BRCA 0.0066 low
ENSG00000169714 CNBP UCS 0.024 low
ENSG00000169714 CNBP KIRC 0.01 low
ENSG00000169714 CNBP PRAD 0.0043 high
ENSG00000169714 CNBP LAML 0.00093 high
ENSG00000169714 CNBP GBM 0.013 low
ENSG00000169714 CNBP CESC 0.02 low
ENSG00000169714 CNBP LIHC 0.0064 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000169714 CNBP GBM Del 0.885379 0.054414 0.486399 0.091854
ENSG00000169714 CNBP PCPG Del 0.899050 0.062820 0.632537 0.574074
ENSG00000169714 CNBP PRAD Amp 3.108938 0.078679 0.467558 0.148374
ENSG00000169714 CNBP UCEC Amp 1.040449 0.111752 0.624581 0.211503