RBP Type	Canonical_RBPs
Diseases	CancerCHIKVSARS-COV-OC43HIVIAVRVSARS-COV-2SINVDengueZika
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	Stress granucleP-body
BulkPerturb-seq	DataSet_01_121 DataSet_01_288

Ensembl ID	ENSG00000169564	Gene ID	5093	Accession	8647
Symbol	PCBP1	Alias	HNRPX;HNRPE1;hnRNP-X;HEL-S-85;hnRNP-E1	Full Name	poly(rC) binding protein 1
Status	Confidence	Length	1727 bases	Strand	Plus strand
Position	2 : 70087477 - 70089203	RNA binding domain	KH_1
Summary	This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000305556	KH_1	PF00013	2e-50	1
ENSP00000305556	KH_1	PF00013	2e-50	2
ENSP00000305556	KH_1	PF00013	2e-50	3

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
28076324	Poly(C)-binding protein 1 mediates drug resistance in colorectal cancer.	Jiani Guo	2017-02-21	Oncotarget
36902478	The Functions of TRIM56 in Antiviral Innate Immunity and Tumorigenesis.	Lin Fu	2023-03-06	International journal of molecular sciences
29138420	Expression of both poly r(C) binding protein 1 (PCBP1) and miRNA-3978 is suppressed in peritoneal gastric cancer metastasis.	Fu-Jian Ji	2017-11-14	Scientific reports
15246275	A posttranscriptional regulator of Kaposi's sarcoma-associated herpesvirus interacts with RNA-binding protein PCBP1 and controls gene expression through the IRES.	Ken Nishimura	2004-08-01	Virology
27911100	Mitochondria and Iron: current questions.	T Bibbin Paul	2017-01-01	Expert review of hematology
35907982	The RNA-binding protein PCBP1 represses lung adenocarcinoma progression by stabilizing DKK1 mRNA and subsequently downregulating β-catenin.	Yujia Zheng	2022-07-30	Journal of translational medicine
19843848	Nuclear receptor coregulators in cancer biology.	W Bert O'Malley	2009-11-01	Cancer research
25559010	Role of heme in cardiovascular physiology and disease.	Teodor Konrad Sawicki	2015-01-05	Journal of the American Heart Association
32922440	Poly C Binding Protein 1 Regulates p62/SQSTM1 mRNA Stability and Autophagic Degradation to Repress Tumor Progression.	Wenliang Zhang	2020-01-01	Frontiers in genetics
19754138	Iron uptake and transport in plants: the good, the bad, and the ionome.	Joe Morrissey	2009-10-01	Chemical reviews
32835748	Management versus miscues in the cytosolic labile iron pool: The varied functions of iron chaperones.	C Caroline Philpott	2020-11-01	Biochimica et biophysica acta. Molecular cell research
35290903	Poly(rC)-binding protein 1 represses ferritinophagy-mediated ferroptosis in head and neck cancer.	Jaewang Lee	2022-05-01	Redox biology
30247716	Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3G.	Zhaolong Li	2018-11-30	Nucleic acids research
31326364	Two ways of escaping from oxidative RNA damage: Selective degradation and cell death.	Takashi Ishii	2019-09-01	DNA repair
33416185	miRNA‑490‑3p promotes the metastatic progression of invasive ductal carcinoma.	Ning Lu	2021-02-01	Oncology reports
37426488	Functional Role of RBP in Osteosarcoma: Regulatory Mechanism and Clinical Therapy.	Ziyuan Que	2023-01-01	Analytical cellular pathology (Amsterdam)
32647012	PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions.	Takashi Ishii	2020-08-21	The Journal of biological chemistry
35795237	PCBP-1 Regulates the Transcription and Alternative Splicing of Inflammation and Ubiquitination-Related Genes in PC12 Cell.	Aishanjiang Yusufujiang	2022-01-01	Frontiers in aging neuroscience
33579665	Biomarkers of nucleic acid oxidation - A summary state-of-the-art.	Mu-Rong Chao	2021-06-01	Redox biology
23823326	Single-stranded DNA-binding proteins: multiple domains for multiple functions.	H Thayne Dickey	2013-07-02	Structure (London, England : 1993)
27836661	Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP).	Kyu Cheol Hwang	2017-01-20	Gene
36406269	Dynamics and energetics of PCBP1 binding to severely oxidized RNA.	Natacha Gillet	2022-01-01	Frontiers in molecular biosciences
18656221	The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation.	Polen Sean	2008-09-01	Virology
31406370	A PCBP1-BolA2 chaperone complex delivers iron for cytosolic [2Fe-2S] cluster assembly.	J Sarju Patel	2019-09-01	Nature chemical biology

Name	Transcript ID	bp	Protein	Translation ID
PCBP1-201	ENST00000303577	1727	356aa	ENSP00000305556

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000169564	homo_sapiens	ENSP00000290341	26.1698	15.078	homo_sapiens	ENSP00000305556	42.4157	24.4382
ENSG00000169564	homo_sapiens	ENSP00000417196	58.0645	45.4094	homo_sapiens	ENSP00000305556	65.7303	51.4045
ENSG00000169564	homo_sapiens	ENSP00000263257	28.0488	16.2602	homo_sapiens	ENSP00000305556	38.764	22.4719
ENSG00000169564	homo_sapiens	ENSP00000505796	73.0458	64.1509	homo_sapiens	ENSP00000305556	76.1236	66.8539
ENSG00000169564	homo_sapiens	ENSP00000365439	30.819	20.0431	homo_sapiens	ENSP00000305556	40.1685	26.1236
ENSG00000169564	homo_sapiens	ENSP00000448762	88.9503	82.8729	homo_sapiens	ENSP00000305556	90.4494	84.2697
ENSG00000169564	homo_sapiens	ENSP00000371634	25.8765	15.192	homo_sapiens	ENSP00000305556	43.5393	25.5618
ENSG00000169564	homo_sapiens	ENSP00000359804	22.205	13.9752	homo_sapiens	ENSP00000305556	40.1685	25.2809
ENSG00000169564	homo_sapiens	ENSP00000258729	25.734	14.8532	homo_sapiens	ENSP00000305556	41.8539	24.1573
ENSG00000169564	homo_sapiens	ENSP00000318177	26.049	16.0839	homo_sapiens	ENSP00000305556	41.8539	25.8427
ENSG00000169564	homo_sapiens	ENSP00000438875	26.43	14.9901	homo_sapiens	ENSP00000305556	37.6404	21.3483
ENSG00000169564	homo_sapiens	ENSP00000471146	20.3481	12.8514	homo_sapiens	ENSP00000305556	42.6966	26.9663

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	nomascus_leucogenys	ENSNLEP00000022598	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	99.1573	98.8764	pan_paniscus	ENSPPAP00000025989	98.0556	97.7778
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	pongo_abelii	ENSPPYP00000013749	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	pan_troglodytes	ENSPTRP00000020647	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	gorilla_gorilla	ENSGGOP00000023163	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	80.0562	79.4944	dasypus_novemcinctus	ENSDNOP00000034664	99.6504	98.951
ENSG00000169564	homo_sapiens	ENSP00000305556	96.6292	94.6629	callithrix_jacchus	ENSCJAP00000071168	98.5673	96.5616
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	callithrix_jacchus	ENSCJAP00000072017	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	cercocebus_atys	ENSCATP00000004155	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	macaca_fascicularis	ENSMFAP00000063749	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	macaca_mulatta	ENSMMUP00000046093	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	macaca_nemestrina	ENSMNEP00000000621	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	95.2247	95.2247	papio_anubis	ENSPANP00000029646	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	mandrillus_leucophaeus	ENSMLEP00000006936	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	90.4494	90.4494	vulpes_vulpes	ENSVVUP00000039348	98.773	98.773
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	mus_spretus	MGP_SPRETEiJ_P0077741	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	equus_asinus	ENSEASP00005056688	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	capra_hircus	ENSCHIP00000003735	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	panthera_leo	ENSPLOP00000016842	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	ailuropoda_melanoleuca	ENSAMEP00000016998	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	91.2921	91.2921	bos_indicus_hybrid	ENSBIXP00005028269	99.0854	99.0854
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	oryctolagus_cuniculus	ENSOCUP00000020092	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	equus_caballus	ENSECAP00000074799	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	99.7191	99.7191	canis_lupus_familiaris	ENSCAFP00845037555	99.7191	99.7191
ENSG00000169564	homo_sapiens	ENSP00000305556	91.0112	90.1685	canis_lupus_familiaris	ENSCAFP00845032185	97.5904	96.6867
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	panthera_pardus	ENSPPRP00000028437	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	marmota_marmota_marmota	ENSMMMP00000005448	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	balaenoptera_musculus	ENSBMSP00010022255	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	cavia_porcellus	ENSCPOP00000012166	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	felis_catus	ENSFCAP00000017172	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	bison_bison_bison	ENSBBBP00000008895	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	monodon_monoceros	ENSMMNP00015020023	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	90.4494	90.4494	sus_scrofa	ENSSSCP00000076382	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	microcebus_murinus	ENSMICP00000022546	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	85.9551	82.8652	octodon_degus	ENSODEP00000000295	88.9535	85.7558
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	jaculus_jaculus	ENSJJAP00000000871	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	ovis_aries_rambouillet	ENSOARP00020007574	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	delphinapterus_leucas	ENSDLEP00000007261	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	physeter_catodon	ENSPCTP00005014669	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	mus_caroli	MGP_CAROLIEiJ_P0074795	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	mus_musculus	ENSMUSP00000054863	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	dipodomys_ordii	ENSDORP00000025060	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	97.191	97.191	mustela_putorius_furo	ENSMPUP00000007117	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	76.9663	75.5618	aotus_nancymaae	ENSANAP00000002964	96.8198	95.053
ENSG00000169564	homo_sapiens	ENSP00000305556	87.3596	85.6742	aotus_nancymaae	ENSANAP00000031286	95.6923	93.8462
ENSG00000169564	homo_sapiens	ENSP00000305556	95.2247	94.382	aotus_nancymaae	ENSANAP00000018293	96.5812	95.7265
ENSG00000169564	homo_sapiens	ENSP00000305556	76.6854	75.5618	aotus_nancymaae	ENSANAP00000027753	96.4664	95.053
ENSG00000169564	homo_sapiens	ENSP00000305556	73.8764	73.0337	aotus_nancymaae	ENSANAP00000008935	96.6912	95.5882
ENSG00000169564	homo_sapiens	ENSP00000305556	79.7753	77.809	aotus_nancymaae	ENSANAP00000018546	95.6229	93.266
ENSG00000169564	homo_sapiens	ENSP00000305556	88.2022	87.9213	aotus_nancymaae	ENSANAP00000016412	94.8641	94.5619
ENSG00000169564	homo_sapiens	ENSP00000305556	89.6067	88.4831	aotus_nancymaae	ENSANAP00000011997	94.6588	93.4718
ENSG00000169564	homo_sapiens	ENSP00000305556	85.6742	83.427	saimiri_boliviensis_boliviensis	ENSSBOP00000038488	89.4428	87.0968
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	chlorocebus_sabaeus	ENSCSAP00000018949	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	57.5843	56.7416	tupaia_belangeri	ENSTBEP00000013625	57.7465	56.9014
ENSG00000169564	homo_sapiens	ENSP00000305556	99.7191	99.7191	mesocricetus_auratus	ENSMAUP00000008419	99.7191	99.7191
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	phocoena_sinus	ENSPSNP00000026858	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	26.6854	25.2809	camelus_dromedarius	ENSCDRP00005013539	87.156	82.5688
ENSG00000169564	homo_sapiens	ENSP00000305556	99.7191	99.4382	carlito_syrichta	ENSTSYP00000031826	99.7191	99.4382
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	panthera_tigris_altaica	ENSPTIP00000004929	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	rattus_norvegicus	ENSRNOP00000092121	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	83.427	83.1461	prolemur_simus	ENSPSMP00000025457	94.2857	93.9683
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	microtus_ochrogaster	ENSMOCP00000008163	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	peromyscus_maniculatus_bairdii	ENSPEMP00000029614	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	99.7191	bos_mutus	ENSBMUP00000027719	100	99.7191
ENSG00000169564	homo_sapiens	ENSP00000305556	96.9101	96.9101	mus_spicilegus	ENSMSIP00000017583	96.9101	96.9101
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	cricetulus_griseus_chok1gshd	ENSCGRP00001014090	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	myotis_lucifugus	ENSMLUP00000012890	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	rhinolophus_ferrumequinum	ENSRFEP00010022321	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	99.7191	99.7191	neovison_vison	ENSNVIP00000004431	99.7191	99.7191
ENSG00000169564	homo_sapiens	ENSP00000305556	91.2921	91.2921	bos_taurus	ENSBTAP00000049383	99.0854	99.0854
ENSG00000169564	homo_sapiens	ENSP00000305556	94.1011	91.2921	heterocephalus_glaber_female	ENSHGLP00000028163	72.5108	70.3463
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	sciurus_vulgaris	ENSSVLP00005020164	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	nannospalax_galili	ENSNGAP00000013270	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	nannospalax_galili	ENSNGAP00000009210	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	96.6292	95.7865	bos_grunniens	ENSBGRP00000008135	100	99.1279
ENSG00000169564	homo_sapiens	ENSP00000305556	99.4382	99.4382	chinchilla_lanigera	ENSCLAP00000025783	99.4382	99.4382
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	cervus_hanglu_yarkandensis	ENSCHYP00000018032	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	99.7191	99.7191	catagonus_wagneri	ENSCWAP00000004817	99.7191	99.7191
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	ictidomys_tridecemlineatus	ENSSTOP00000026830	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	97.191	97.191	otolemur_garnettii	ENSOGAP00000018442	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	94.1011	91.0112	cebus_imitator	ENSCCAP00000022814	92.5414	89.5028
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	cebus_imitator	ENSCCAP00000004600	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	urocitellus_parryii	ENSUPAP00010006802	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	moschus_moschiferus	ENSMMSP00000013586	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	99.1573	99.1573	rhinopithecus_roxellana	ENSRROP00000002392	93.883	93.883
ENSG00000169564	homo_sapiens	ENSP00000305556	92.1348	92.1348	rhinopithecus_roxellana	ENSRROP00000003137	98.7952	98.7952
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	mus_pahari	MGP_PahariEiJ_P0050906	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	100	100	propithecus_coquereli	ENSPCOP00000028562	100	100
ENSG00000169564	homo_sapiens	ENSP00000305556	54.4944	37.3596	caenorhabditis_elegans	Y119D3B.17.2	44.9074	30.787
ENSG00000169564	homo_sapiens	ENSP00000305556	26.9663	16.2921	caenorhabditis_elegans	Y59A8B.10d.1	23.0216	13.9089
ENSG00000169564	homo_sapiens	ENSP00000305556	35.9551	19.382	caenorhabditis_elegans	C36E6.1b.1	19.9688	10.7644
ENSG00000169564	homo_sapiens	ENSP00000305556	34.8315	18.2584	caenorhabditis_elegans	M01A10.1.1	21.1604	11.0921
ENSG00000169564	homo_sapiens	ENSP00000305556	29.7753	15.1685	caenorhabditis_elegans	M88.5c.1	12.4122	6.32318
ENSG00000169564	homo_sapiens	ENSP00000305556	35.1124	17.9775	caenorhabditis_elegans	C12D8.1b.1	20.4583	10.4746
ENSG00000169564	homo_sapiens	ENSP00000305556	64.6067	48.5955	drosophila_melanogaster	FBpp0293521	40.1396	30.192
ENSG00000169564	homo_sapiens	ENSP00000305556	35.1124	21.3483	drosophila_melanogaster	FBpp0306419	16.0256	9.74359
ENSG00000169564	homo_sapiens	ENSP00000305556	34.8315	20.2247	drosophila_melanogaster	FBpp0293680	19.4357	11.2853
ENSG00000169564	homo_sapiens	ENSP00000305556	36.236	19.6629	drosophila_melanogaster	FBpp0428307	16.1857	8.78294
ENSG00000169564	homo_sapiens	ENSP00000305556	52.809	37.6404	ciona_intestinalis	ENSCINP00000001984	52.6611	37.535
ENSG00000169564	homo_sapiens	ENSP00000305556	22.4719	11.7978	ciona_intestinalis	ENSCINP00000025950	28.169	14.7887
ENSG00000169564	homo_sapiens	ENSP00000305556	38.2022	20.2247	ciona_intestinalis	ENSCINP00000008726	23.0118	12.1827
ENSG00000169564	homo_sapiens	ENSP00000305556	25.2809	17.1348	ciona_intestinalis	ENSCINP00000019569	28.3019	19.1824
ENSG00000169564	homo_sapiens	ENSP00000305556	25.8427	15.7303	ciona_intestinalis	ENSCINP00000030435	34.981	21.2928
ENSG00000169564	homo_sapiens	ENSP00000305556	36.5169	20.5056	astyanax_mexicanus	ENSAMXP00000028943	41.4013	23.2484
ENSG00000169564	homo_sapiens	ENSP00000305556	25.5618	17.6966	ciona_savignyi	ENSCSAVP00000004755	43.3333	30
ENSG00000169564	homo_sapiens	ENSP00000305556	23.8764	18.2584	ciona_savignyi	ENSCSAVP00000007214	69.6721	53.2787
ENSG00000169564	homo_sapiens	ENSP00000305556	38.2022	20.7865	ciona_savignyi	ENSCSAVP00000018813	23.4483	12.7586
ENSG00000169564	homo_sapiens	ENSP00000305556	28.9326	18.8202	ciona_savignyi	ENSCSAVP00000007375	33.3333	21.6828
ENSG00000169564	homo_sapiens	ENSP00000305556	31.1798	19.382	ciona_savignyi	ENSCSAVP00000005505	20.5176	12.7542
ENSG00000169564	homo_sapiens	ENSP00000305556	16.0112	8.98876	ciona_savignyi	ENSCSAVP00000005450	16.8639	9.46746

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000981	enables DNA-binding transcription factor activity, RNA polymerase II-specific	1	IEA	Homo_sapiens(9606)	Function
GO:0003697	enables single-stranded DNA binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	2	HDA,IDA	Homo_sapiens(9606)	Function
GO:0003729	enables mRNA binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005654	is_active_in nucleoplasm	3	IBA,IDA,TAS	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	IDA	Homo_sapiens(9606)	Component
GO:0014069	located_in postsynaptic density	1	IEA	Homo_sapiens(9606)	Component
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0016607	located_in nuclear speck	1	IDA	Homo_sapiens(9606)	Component
GO:0036464	located_in cytoplasmic ribonucleoprotein granule	1	IDA	Homo_sapiens(9606)	Component
GO:0039694	involved_in viral RNA genome replication	1	IDA	Homo_sapiens(9606)	Process
GO:0045296	enables cadherin binding	1	HDA	Homo_sapiens(9606)	Function
GO:0045944	involved_in positive regulation of transcription by RNA polymerase II	1	IBA	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:0098847	enables sequence-specific single stranded DNA binding	1	IEA	Homo_sapiens(9606)	Function
GO:1990904	part_of ribonucleoprotein complex	1	IEA	Homo_sapiens(9606)	Component