Welcome to
RBP World!
Functions and Diseases
RBP Type | Canonical_RBPs |
Diseases | CancerSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVDengueZika |
Drug | N.A. |
Main interacting RNAs | mRNA |
Moonlighting functions | N.A. |
Localizations | Stress granucle |
BulkPerturb-seq | N.A. |
Description
Ensembl ID | ENSG00000169045 | Gene ID | 3187 | Accession | 5041 |
Symbol | HNRNPH1 | Alias | HNRPH;HNRPH1;NEDCDS;hnRNPH | Full Name | heterogeneous nuclear ribonucleoprotein H1 |
Status | Confidence | Length | 20607 bases | Strand | Minus strand |
Position | 5 : 179614178 - 179634784 | RNA binding domain | zf-RNPHF , RRM_1 | ||
Summary | This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012] |
RNA binding domains (RBDs)
Protein | Domain | Pfam ID | E-value | Domain number |
---|---|---|---|---|
ENSP00000426275 | RRM_1 | PF00076 | 1e-32 | 1 |
ENSP00000426275 | RRM_1 | PF00076 | 1e-32 | 2 |
ENSP00000426275 | RRM_1 | PF00076 | 1e-32 | 3 |
ENSP00000426275 | zf-RNPHF | PF08080 | 1.4e-23 | 4 |
ENSP00000516644 | RRM_1 | PF00076 | 1.2e-32 | 1 |
ENSP00000516644 | RRM_1 | PF00076 | 1.2e-32 | 2 |
ENSP00000516644 | RRM_1 | PF00076 | 1.2e-32 | 3 |
ENSP00000516644 | zf-RNPHF | PF08080 | 8.2e-13 | 4 |
ENSP00000349168 | RRM_1 | PF00076 | 1.3e-32 | 1 |
ENSP00000349168 | RRM_1 | PF00076 | 1.3e-32 | 2 |
ENSP00000349168 | RRM_1 | PF00076 | 1.3e-32 | 3 |
ENSP00000349168 | zf-RNPHF | PF08080 | 7.1e-24 | 4 |
ENSP00000377082 | RRM_1 | PF00076 | 1.3e-32 | 1 |
ENSP00000377082 | RRM_1 | PF00076 | 1.3e-32 | 2 |
ENSP00000377082 | RRM_1 | PF00076 | 1.3e-32 | 3 |
ENSP00000377082 | zf-RNPHF | PF08080 | 7.1e-24 | 4 |
ENSP00000397797 | RRM_1 | PF00076 | 1.3e-32 | 1 |
ENSP00000397797 | RRM_1 | PF00076 | 1.3e-32 | 2 |
ENSP00000397797 | RRM_1 | PF00076 | 1.3e-32 | 3 |
ENSP00000397797 | zf-RNPHF | PF08080 | 7.1e-24 | 4 |
ENSP00000327539 | RRM_1 | PF00076 | 1.6e-32 | 1 |
ENSP00000327539 | RRM_1 | PF00076 | 1.6e-32 | 2 |
ENSP00000327539 | RRM_1 | PF00076 | 1.6e-32 | 3 |
ENSP00000327539 | zf-RNPHF | PF08080 | 7.7e-24 | 4 |
ENSP00000424087 | RRM_1 | PF00076 | 2.4e-22 | 1 |
ENSP00000424087 | RRM_1 | PF00076 | 2.4e-22 | 2 |
ENSP00000427388 | RRM_1 | PF00076 | 3.3e-20 | 1 |
ENSP00000427388 | RRM_1 | PF00076 | 3.3e-20 | 2 |
ENSP00000426518 | RRM_1 | PF00076 | 5.7e-18 | 1 |
ENSP00000426518 | RRM_1 | PF00076 | 5.7e-18 | 2 |
ENSP00000428620 | RRM_1 | PF00076 | 1.3e-16 | 1 |
ENSP00000428620 | RRM_1 | PF00076 | 1.3e-16 | 2 |
ENSP00000428620 | zf-RNPHF | PF08080 | 1.4e-24 | 3 |
ENSP00000430970 | RRM_1 | PF00076 | 4.3e-16 | 1 |
ENSP00000427986 | RRM_1 | PF00076 | 6.2e-16 | 1 |
ENSP00000427986 | RRM_1 | PF00076 | 6.2e-16 | 2 |
ENSP00000430156 | RRM_1 | PF00076 | 7.9e-13 | 1 |
ENSP00000423140 | RRM_1 | PF00076 | 3.9e-10 | 1 |
ENSP00000427408 | RRM_1 | PF00076 | 4.8e-10 | 1 |
ENSP00000427408 | zf-RNPHF | PF08080 | 1.3e-15 | 2 |
ENSP00000420850 | RRM_1 | PF00076 | 4.9e-10 | 1 |
ENSP00000425732 | RRM_1 | PF00076 | 5e-10 | 1 |
ENSP00000425851 | RRM_1 | PF00076 | 6.3e-10 | 1 |
ENSP00000429481 | RRM_1 | PF00076 | 9.4e-09 | 1 |
ENSP00000429481 | zf-RNPHF | PF08080 | 6.8e-24 | 2 |
ENSP00000429270 | RRM_1 | PF00076 | 9.6e-09 | 1 |
ENSP00000429270 | zf-RNPHF | PF08080 | 1.1e-23 | 2 |
ENSP00000421695 | RRM_1 | PF00076 | 3.7e-08 | 1 |
ENSP00000425343 | RRM_1 | PF00076 | 3.7e-07 | 1 |
ENSP00000429661 | RRM_1 | PF00076 | 9.3e-07 | 1 |
RNA binding proteomes (RBPomes)
Pubmed ID | Full Name | Cell | Author | Time | Doi |
---|
Literatures on RNA binding capacity
Pubmed ID | Title | Author | Time | Journal |
---|---|---|---|---|
37323535 | G-quadruplexes and associated proteins in aging and Alzheimer's disease. | J M MJ Vijay | 2023-01-01 | Frontiers in aging |
35552415 | Transcriptome analysis of clock disrupted cancer cells reveals differential alternative splicing of cancer hallmarks genes. | Deeksha Malhan | 2022-05-12 | NPJ systems biology and applications |
34295818 | HNRNPH1 Is a Novel Regulator Of Cellular Proliferation and Disease Progression in Chronic Myeloid Leukemia. | Menghan Liu | 2021-01-01 | Frontiers in oncology |
34389706 | SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns. | Kazuhiro Fukumura | 2021-08-13 | Nature communications |
29362363 | HNRNPH1 is required for rhabdomyosarcoma cell growth and survival. | Yanfeng Li | 2018-01-24 | Oncogenesis |
21624892 | EBP1 and DRBP76/NF90 binding proteins are included in the major histocompatibility complex class II RNA operon. | Carmela Corso | 2011-09-01 | Nucleic acids research |
33544852 | Anatomy of noncovalent interactions between the nucleobases or ribose and π-containing amino acids in RNA-protein complexes. | A Katie Wilson | 2021-02-26 | Nucleic acids research |
31407506 | Fusion transcripts: Unexploited vulnerabilities in cancer? | Carla Neckles | 2020-01-01 | Wiley interdisciplinary reviews. RNA |
30999914 | Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer. | Shouping Xu | 2019-04-18 | Molecular cancer |
21572999 | Versatility of MicroRNA biogenesis. | Naama Volk | 2011-05-10 | PloS one |
31815633 | Tumorigenesis, diagnosis, and therapeutic potential of exosomes in liver cancer. | Hongbo Wang | 2019-12-09 | Journal of hematology & oncology |
34873036 | Distinct roles of hnRNPH1 low-complexity domains in splicing and transcription. | Hye Ga Kim | 2021-12-14 | Proceedings of the National Academy of Sciences of the United States of America |
36572750 | Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. | Namrata Rastogi | 2023-02-01 | Leukemia |
27088854 | A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation. | Xinjian Li | 2016-05-01 | Nature cell biology |
36175485 | Phase separation of low-complexity domains in cellular function and disease. | Jiwon Lee | 2022-09-01 | Experimental & molecular medicine |
27520967 | Arginine methylation enhances the RNA chaperone activity of the West Nile virus host factor AUF1 p45. | Susann Friedrich | 2016-10-01 | RNA (New York, N.Y.) |
31511320 | HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction. | Carla Neckles | 2019-12-01 | RNA (New York, N.Y.) |
32793288 | Genome-Wide Profiling of Alternative Splicing Signature Reveals Prognostic Predictor for Esophageal Carcinoma. | Jian-Rong Sun | 2020-01-01 | Frontiers in genetics |
35739118 | hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells. | Shenglei Feng | 2022-06-23 | Nature communications |
36672331 | Regulation of EWSR1-FLI1 Function by Post-Transcriptional and Post-Translational Modifications. | Le Yu | 2023-01-06 | Cancers |
34759793 | Interconnected Gene Networks Underpin the Clinical Overlap of HNRNPH1-Related and Rubinstein-Taybi Intellectual Disability Syndromes. | Lidia Larizza | 2021-01-01 | Frontiers in neuroscience |
35639772 | HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript. | Tam Vo | 2022-06-24 | Nucleic acids research |
Transcripts
Name | Transcript ID | bp | Protein | Translation ID |
---|---|---|---|---|
HNRNPH1-201 | ENST00000329433 | 2190 | 472aa | ENSP00000327539 |
HNRNPH1-203 | ENST00000393432 | 2240 | 449aa | ENSP00000377082 |
HNRNPH1-249 | ENST00000706924 | 2068 | 445aa | ENSP00000516644 |
HNRNPH1-206 | ENST00000502904 | 2913 | No protein | - |
HNRNPH1-214 | ENST00000506721 | 2081 | 184aa | ENSP00000420850 |
HNRNPH1-217 | ENST00000510431 | 2127 | 184aa | ENSP00000423140 |
HNRNPH1-204 | ENST00000442819 | 2248 | 449aa | ENSP00000397797 |
HNRNPH1-213 | ENST00000505811 | 2650 | 449aa | ENSP00000424087 |
HNRNPH1-228 | ENST00000515714 | 2568 | 449aa | ENSP00000425343 |
HNRNPH1-220 | ENST00000513225 | 2446 | 449aa | ENSP00000426518 |
HNRNPH1-202 | ENST00000356731 | 3667 | 449aa | ENSP00000349168 |
HNRNPH1-227 | ENST00000515481 | 5564 | No protein | - |
HNRNPH1-223 | ENST00000514332 | 2444 | No protein | - |
HNRNPH1-216 | ENST00000510411 | 2100 | 429aa | ENSP00000426275 |
HNRNPH1-218 | ENST00000510678 | 1991 | 184aa | ENSP00000425851 |
HNRNPH1-215 | ENST00000508103 | 2045 | 184aa | ENSP00000425732 |
HNRNPH1-246 | ENST00000523921 | 2167 | 429aa | ENSP00000429270 |
HNRNPH1-225 | ENST00000515158 | 2548 | 449aa | ENSP00000421695 |
HNRNPH1-237 | ENST00000521116 | 2550 | 449aa | ENSP00000429661 |
HNRNPH1-245 | ENST00000523449 | 793 | 117aa | ENSP00000429673 |
HNRNPH1-247 | ENST00000524179 | 598 | No protein | - |
HNRNPH1-239 | ENST00000521720 | 539 | No protein | - |
HNRNPH1-205 | ENST00000502632 | 1509 | No protein | - |
HNRNPH1-235 | ENST00000519958 | 885 | 131aa | ENSP00000427845 |
HNRNPH1-243 | ENST00000523136 | 143 | 48aa | ENSP00000430445 |
HNRNPH1-210 | ENST00000504549 | 980 | No protein | - |
HNRNPH1-224 | ENST00000514731 | 1371 | No protein | - |
HNRNPH1-238 | ENST00000521173 | 831 | 40aa | ENSP00000428620 |
HNRNPH1-207 | ENST00000503105 | 559 | 164aa | ENSP00000427408 |
HNRNPH1-211 | ENST00000504779 | 792 | 40aa | ENSP00000422955 |
HNRNPH1-236 | ENST00000520415 | 620 | No protein | - |
HNRNPH1-229 | ENST00000518548 | 527 | No protein | - |
HNRNPH1-244 | ENST00000523137 | 563 | 166aa | ENSP00000427986 |
HNRNPH1-231 | ENST00000519056 | 530 | 155aa | ENSP00000430970 |
HNRNPH1-242 | ENST00000522958 | 580 | No protein | - |
HNRNPH1-240 | ENST00000521790 | 549 | No protein | - |
HNRNPH1-209 | ENST00000504348 | 594 | 168aa | ENSP00000427388 |
HNRNPH1-248 | ENST00000524180 | 997 | No protein | - |
HNRNPH1-222 | ENST00000513972 | 761 | No protein | - |
HNRNPH1-234 | ENST00000519943 | 748 | No protein | - |
HNRNPH1-233 | ENST00000519707 | 582 | No protein | - |
HNRNPH1-232 | ENST00000519455 | 451 | No protein | - |
HNRNPH1-212 | ENST00000505087 | 592 | No protein | - |
HNRNPH1-219 | ENST00000512273 | 501 | 40aa | ENSP00000427351 |
HNRNPH1-208 | ENST00000503664 | 569 | 49aa | ENSP00000426726 |
HNRNPH1-226 | ENST00000515446 | 368 | No protein | - |
HNRNPH1-221 | ENST00000513230 | 248 | No protein | - |
HNRNPH1-241 | ENST00000522256 | 492 | 28aa | ENSP00000429179 |
HNRNPH1-230 | ENST00000518602 | 291 | No protein | - |
GWAS
ensgID | SNP | Chromosome | Position | Trait | PubmedID | Or or BEAT | EFO ID |
---|
Protein-Protein Interaction (PPI)
Paralogs
Ensembl ID | Source | Target | ||||||
---|---|---|---|---|---|---|---|---|
Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
ENSG00000169045 | homo_sapiens | ENSP00000405738 | 28.1938 | 19.0896 | homo_sapiens | ENSP00000377082 | 42.7617 | 28.9532 |
ENSG00000169045 | homo_sapiens | ENSP00000418748 | 25.802 | 17.0153 | homo_sapiens | ENSP00000377082 | 41.2027 | 27.1715 |
ENSG00000169045 | homo_sapiens | ENSP00000265866 | 72.2543 | 64.4509 | homo_sapiens | ENSP00000377082 | 55.6793 | 49.6659 |
ENSG00000169045 | homo_sapiens | ENSP00000429807 | 16.6833 | 9.29071 | homo_sapiens | ENSP00000377082 | 37.1938 | 20.7127 |
ENSG00000169045 | homo_sapiens | ENSP00000507787 | 87.7108 | 78.0723 | homo_sapiens | ENSP00000377082 | 81.069 | 72.1604 |
ENSG00000169045 | homo_sapiens | ENSP00000254799 | 45 | 31.875 | homo_sapiens | ENSP00000377082 | 48.1069 | 34.0757 |
ENSG00000169045 | homo_sapiens | ENSP00000363228 | 18.4549 | 9.65665 | homo_sapiens | ENSP00000377082 | 38.3074 | 20.0445 |
ENSG00000169045 | homo_sapiens | ENSP00000361927 | 98.2183 | 96.2138 | homo_sapiens | ENSP00000377082 | 98.2183 | 96.2138 |
ENSG00000169045 | homo_sapiens | ENSP00000518312 | 92.4779 | 92.0354 | homo_sapiens | ENSP00000377082 | 93.0958 | 92.6503 |
Orthologs
Ensembl ID | Source | Target | ||||||
---|---|---|---|---|---|---|---|---|
Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 60.3563 | 56.7929 | nomascus_leucogenys | ENSNLEP00000043126 | 85.489 | 80.4416 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 73.2739 | 68.1515 | pan_paniscus | ENSPPAP00000028208 | 83.715 | 77.8626 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 94.2094 | 93.0958 | pongo_abelii | ENSPPYP00000038840 | 98.6014 | 97.4359 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 56.7929 | 53.6748 | pan_troglodytes | ENSPTRP00000079124 | 85 | 80.3333 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 100 | 100 | gorilla_gorilla | ENSGGOP00000052169 | 93.5417 | 93.5417 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.1047 | 96.6592 | ornithorhynchus_anatinus | ENSOANP00000034079 | 92.3729 | 91.9492 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 75.2784 | 66.3697 | sarcophilus_harrisii | ENSSHAP00000015004 | 73.7991 | 65.0655 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.1047 | 96.6592 | sarcophilus_harrisii | ENSSHAP00000043895 | 92.3729 | 91.9492 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 75.7238 | 68.1515 | sarcophilus_harrisii | ENSSHAP00000027600 | 73.1183 | 65.8064 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 49.6659 | 49.2205 | notamacropus_eugenii | ENSMEUP00000013312 | 50.9132 | 50.4566 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.755 | 89.3096 | choloepus_hoffmanni | ENSCHOP00000003400 | 91.7995 | 91.344 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 51.8931 | 51.4477 | choloepus_hoffmanni | ENSCHOP00000001427 | 85.6618 | 84.9265 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 68.5969 | 62.8062 | dasypus_novemcinctus | ENSDNOP00000021847 | 75.6757 | 69.2875 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 72.1604 | 71.7149 | erinaceus_europaeus | ENSEEUP00000012189 | 89.7507 | 89.1967 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 55.2339 | 55.0111 | erinaceus_europaeus | ENSEEUP00000010011 | 98.8048 | 98.4064 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 90.2004 | 90.2004 | echinops_telfairi | ENSETEP00000009166 | 85.9873 | 85.9873 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 28.7305 | 26.5033 | callithrix_jacchus | ENSCJAP00000090023 | 71.2707 | 65.7459 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | cercocebus_atys | ENSCATP00000022247 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 93.0958 | 92.8731 | macaca_fascicularis | ENSMFAP00000013329 | 92.4779 | 92.2566 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | macaca_mulatta | ENSMMUP00000054756 | 88.664 | 88.4615 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | macaca_nemestrina | ENSMNEP00000016774 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | papio_anubis | ENSPANP00000026044 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 70.8241 | 67.4833 | mandrillus_leucophaeus | ENSMLEP00000007166 | 76.8116 | 73.1884 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 75.9465 | 75.7238 | tursiops_truncatus | ENSTTRP00000000443 | 77.6765 | 77.4487 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.1047 | vulpes_vulpes | ENSVVUP00000001724 | 92.7966 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 39.8664 | 39.8664 | mus_spretus | MGP_SPRETEiJ_P0027823 | 100 | 100 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | equus_asinus | ENSEASP00005054304 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 93.7639 | 92.8731 | capra_hircus | ENSCHIP00000023887 | 90.9287 | 90.0648 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 43.4298 | 37.4165 | loxodonta_africana | ENSLAFP00000026035 | 75 | 64.6154 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 49.2205 | 45.2116 | loxodonta_africana | ENSLAFP00000027820 | 78.6477 | 72.242 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | panthera_leo | ENSPLOP00000002429 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 92.2049 | 91.5368 | ailuropoda_melanoleuca | ENSAMEP00000026904 | 88.651 | 88.0086 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | bos_indicus_hybrid | ENSBIXP00005001001 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.1047 | oryctolagus_cuniculus | ENSOCUP00000036364 | 74.1117 | 73.7733 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 100 | 100 | equus_caballus | ENSECAP00000012462 | 100 | 100 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.1047 | canis_lupus_familiaris | ENSCAFP00845011289 | 92.7966 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | panthera_pardus | ENSPPRP00000015693 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | marmota_marmota_marmota | ENSMMMP00000011968 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | balaenoptera_musculus | ENSBMSP00010011606 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 84.4098 | 83.9644 | cavia_porcellus | ENSCPOP00000031321 | 96.9309 | 96.4194 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 83.0735 | 81.2918 | cavia_porcellus | ENSCPOP00000028408 | 96.8831 | 94.8052 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | felis_catus | ENSFCAP00000058591 | 91.4405 | 91.2317 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | ursus_americanus | ENSUAMP00000014250 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 33.853 | 33.6303 | monodelphis_domestica | ENSMODP00000039173 | 95.5975 | 94.9686 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | bison_bison_bison | ENSBBBP00000004187 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 13.1403 | 12.9176 | monodon_monoceros | ENSMMNP00015004587 | 81.9444 | 80.5556 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | monodon_monoceros | ENSMMNP00015004140 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.5323 | 87.7506 | sus_scrofa | ENSSSCP00000020174 | 85.3503 | 83.6518 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | microcebus_murinus | ENSMICP00000020524 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.755 | 88.196 | microcebus_murinus | ENSMICP00000029638 | 89.5556 | 88 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 99.7773 | 99.5546 | octodon_degus | ENSODEP00000001520 | 99.5556 | 99.3333 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.1047 | jaculus_jaculus | ENSJJAP00000013467 | 92.7966 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 17.3719 | 17.1492 | ovis_aries_rambouillet | ENSOARP00020013319 | 91.7647 | 90.5882 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 92.8731 | 91.5368 | ursus_maritimus | ENSUMAP00000033610 | 88.9126 | 87.6333 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 67.9287 | 67.4833 | ochotona_princeps | ENSOPRP00000003228 | 89.9705 | 89.3805 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 26.5033 | 25.6125 | delphinapterus_leucas | ENSDLEP00000021343 | 93.7008 | 90.5512 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 100 | 100 | physeter_catodon | ENSPCTP00005001932 | 100 | 100 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 84.8552 | 84.8552 | mus_caroli | MGP_CAROLIEiJ_P0026448 | 66.3763 | 66.3763 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.3274 | 96.882 | mus_musculus | ENSMUSP00000076989 | 92.5847 | 92.161 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.3274 | 96.6592 | dipodomys_ordii | ENSDORP00000020835 | 92.5847 | 91.9492 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 100 | 100 | mustela_putorius_furo | ENSMPUP00000000692 | 100 | 100 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.1047 | aotus_nancymaae | ENSANAP00000035620 | 92.7966 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | saimiri_boliviensis_boliviensis | ENSSBOP00000010981 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 81.5145 | 81.2918 | vicugna_pacos | ENSVPAP00000006964 | 83.3713 | 83.1435 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.9777 | 89.0869 | chlorocebus_sabaeus | ENSCSAP00000004670 | 95.5083 | 94.5626 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 69.7105 | 68.3742 | tupaia_belangeri | ENSTBEP00000010579 | 73.4742 | 72.0657 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.3274 | 97.1047 | mesocricetus_auratus | ENSMAUP00000012740 | 92.5847 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | phocoena_sinus | ENSPSNP00000011862 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 13.5857 | 13.363 | phocoena_sinus | ENSPSNP00000004387 | 74.3902 | 73.1707 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.1047 | 96.882 | camelus_dromedarius | ENSCDRP00005008190 | 92.3729 | 92.161 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 93.3185 | 91.5368 | carlito_syrichta | ENSTSYP00000031909 | 87.4739 | 85.8038 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.196 | 87.9733 | panthera_tigris_altaica | ENSPTIP00000025957 | 92.74 | 92.5059 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.3274 | 97.1047 | rattus_norvegicus | ENSRNOP00000079947 | 92.5847 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | prolemur_simus | ENSPSMP00000016498 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.3274 | 97.1047 | microtus_ochrogaster | ENSMOCP00000024025 | 92.5847 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 82.6281 | 82.4053 | sorex_araneus | ENSSARP00000002737 | 84.7032 | 84.4749 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.3274 | 97.1047 | peromyscus_maniculatus_bairdii | ENSPEMP00000021126 | 92.5847 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | bos_mutus | ENSBMUP00000027577 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 91.9822 | 91.5368 | mus_spicilegus | ENSMSIP00000011158 | 91.5743 | 91.1308 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 71.2695 | 68.5969 | cricetulus_griseus_chok1gshd | ENSCGRP00001016992 | 92.7536 | 89.2754 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 81.2918 | 80.8463 | pteropus_vampyrus | ENSPVAP00000007243 | 84.2956 | 83.8337 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 90.6459 | 90.4232 | myotis_lucifugus | ENSMLUP00000015156 | 91.8736 | 91.6479 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 47.216 | 43.8753 | myotis_lucifugus | ENSMLUP00000018362 | 75.4448 | 70.1068 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 79.7327 | 75.5011 | myotis_lucifugus | ENSMLUP00000021202 | 81.3636 | 77.0455 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 78.3964 | 71.0468 | vombatus_ursinus | ENSVURP00010028958 | 77.7042 | 70.4194 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.1047 | 96.6592 | vombatus_ursinus | ENSVURP00010009839 | 92.3729 | 91.9492 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.1047 | rhinolophus_ferrumequinum | ENSRFEP00010031857 | 92.7966 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 95.9911 | 95.7684 | neovison_vison | ENSNVIP00000012416 | 92.6882 | 92.4731 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | bos_taurus | ENSBTAP00000074169 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | heterocephalus_glaber_female | ENSHGLP00000026080 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 94.6548 | 93.9866 | rhinopithecus_bieti | ENSRBIP00000032510 | 97.4771 | 96.789 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 91.5368 | 90.4232 | rhinopithecus_bieti | ENSRBIP00000004897 | 97.1631 | 95.9811 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 87.9733 | 86.1915 | canis_lupus_dingo | ENSCAFP00020003277 | 89.9772 | 88.1549 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | sciurus_vulgaris | ENSSVLP00005005468 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 54.343 | 49.6659 | phascolarctos_cinereus | ENSPCIP00000036919 | 76.489 | 69.906 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.1047 | 96.6592 | phascolarctos_cinereus | ENSPCIP00000009733 | 88.9796 | 88.5714 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 73.9421 | 72.3831 | procavia_capensis | ENSPCAP00000006269 | 98.2249 | 96.1538 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 82.4053 | 79.9555 | nannospalax_galili | ENSNGAP00000022244 | 91.8114 | 89.0819 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | bos_grunniens | ENSBGRP00000006338 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 90.2004 | 89.9777 | chinchilla_lanigera | ENSCLAP00000019860 | 92.2551 | 92.0273 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | cervus_hanglu_yarkandensis | ENSCHYP00000037668 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | catagonus_wagneri | ENSCWAP00000000522 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | ictidomys_tridecemlineatus | ENSSTOP00000027319 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.1047 | otolemur_garnettii | ENSOGAP00000011318 | 92.7966 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | cebus_imitator | ENSCCAP00000017587 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.1047 | urocitellus_parryii | ENSUPAP00010003508 | 92.7966 | 92.3729 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 56.5702 | 55.4566 | moschus_moschiferus | ENSMMSP00000027419 | 96.5779 | 94.6768 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 91.5368 | 90.2004 | rhinopithecus_roxellana | ENSRROP00000005243 | 97.1631 | 95.7447 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 91.314 | 89.9777 | rhinopithecus_roxellana | ENSRROP00000036626 | 96.9267 | 95.5083 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 99.7773 | 99.7773 | mus_pahari | MGP_PahariEiJ_P0033222 | 99.7773 | 99.7773 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 97.5501 | 97.3274 | propithecus_coquereli | ENSPCOP00000010586 | 92.7966 | 92.5847 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 52.784 | 41.6481 | ciona_intestinalis | ENSCINP00000003632 | 64.9315 | 51.2329 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 70.3786 | 58.3519 | petromyzon_marinus | ENSPMAP00000000855 | 66.9492 | 55.5085 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 57.6837 | 47.6615 | eptatretus_burgeri | ENSEBUP00000014476 | 72.1448 | 59.61 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 65.9243 | 52.784 | eptatretus_burgeri | ENSEBUP00000003713 | 68.3603 | 54.7344 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 80.1782 | 73.2739 | callorhinchus_milii | ENSCMIP00000013099 | 81.448 | 74.4344 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 84.6325 | 79.9555 | latimeria_chalumnae | ENSLACP00000022878 | 85.5856 | 80.8559 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.8641 | 86.1915 | chrysemys_picta_bellii | ENSCPBP00000012622 | 76 | 73.7143 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 86.1915 | 82.6281 | crocodylus_porosus | ENSCPRP00005016689 | 78.3401 | 75.1012 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.755 | 86.8597 | laticauda_laticaudata | ENSLLTP00000010864 | 79.1749 | 76.6208 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.755 | 86.8597 | notechis_scutatus | ENSNSUP00000000160 | 79.1749 | 76.6208 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.755 | 86.8597 | pseudonaja_textilis | ENSPTXP00000019492 | 79.1749 | 76.6208 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.8641 | 85.9688 | anas_platyrhynchos_platyrhynchos | ENSAPLP00000010092 | 74.026 | 71.6141 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.8641 | 85.7461 | gallus_gallus | ENSGALP00010020905 | 75.5682 | 72.9167 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.8641 | 85.7461 | meleagris_gallopavo | ENSMGAP00000007470 | 82.438 | 79.5455 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.196 | 84.8552 | serinus_canaria | ENSSCAP00000015691 | 72.3949 | 69.6526 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.196 | 84.6325 | parus_major | ENSPMJP00000010409 | 68.0412 | 65.2921 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.755 | 86.8597 | podarcis_muralis | ENSPMRP00000009045 | 82.4131 | 79.7546 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 87.9733 | 84.8552 | geospiza_fortis | ENSGFOP00000007548 | 79.6371 | 76.8145 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.196 | 84.8552 | taeniopygia_guttata | ENSTGUP00000028989 | 69.7183 | 67.0775 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.755 | 86.8597 | salvator_merianae | ENSSMRP00000022252 | 82.4131 | 79.7546 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.5323 | 86.4143 | pelodiscus_sinensis | ENSPSIP00000003351 | 78.0583 | 75.3398 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.6414 | 85.9688 | gopherus_evgoodei | ENSGEVP00005006515 | 75.8095 | 73.5238 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.8641 | 86.1915 | chelonoidis_abingdonii | ENSCABP00000017980 | 76 | 73.7143 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 89.755 | 87.0824 | struthio_camelus_australis | ENSSCUP00000003925 | 78.2524 | 75.9223 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 83.5189 | 80.4009 | anser_brachyrhynchus | ENSABRP00000000659 | 78.9474 | 76 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.4187 | 85.0779 | strigops_habroptila | ENSSHBP00005009572 | 78.6139 | 75.6436 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.8641 | 86.1915 | terrapene_carolina_triunguis | ENSTMTP00000030286 | 76 | 73.7143 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.8641 | 85.7461 | aquila_chrysaetos_chrysaetos | ENSACCP00020022063 | 76.8786 | 74.1811 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 87.9733 | 84.1871 | ficedula_albicollis | ENSFALP00000030752 | 70.7885 | 67.7419 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 88.4187 | 84.4098 | coturnix_japonica | ENSCJPP00005005504 | 76.4933 | 73.025 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 43.8753 | 39.6437 | tetraodon_nigroviridis | ENSTNIP00000011851 | 76.0618 | 68.7259 |
ENSG00000169045 | homo_sapiens | ENSP00000377082 | 83.2962 | 75.9465 | leptobrachium_leishanense | ENSLLEP00000035278 | 81.3043 | 74.1304 |
Gene Ontology
Go ID | Go term | No. evidence | Entries | Species | Category |
---|---|---|---|---|---|
GO:0000398 | involved_in mRNA splicing, via spliceosome | 1 | IC | Homo_sapiens(9606) | Process |
GO:0003723 | enables RNA binding | 3 | HDA,IBA,IDA | Homo_sapiens(9606) | Function |
GO:0005515 | enables protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0005634 | located_in nucleus | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0005654 | is_active_in nucleoplasm | 3 | IBA,IDA,TAS | Homo_sapiens(9606) | Component |
GO:0005829 | located_in cytosol | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0006396 | involved_in RNA processing | 1 | TAS | Homo_sapiens(9606) | Process |
GO:0008266 | enables poly(U) RNA binding | 1 | TAS | Homo_sapiens(9606) | Function |
GO:0016020 | located_in membrane | 1 | HDA | Homo_sapiens(9606) | Component |
GO:0042802 | enables identical protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0043484 | involved_in regulation of RNA splicing | 2 | IBA,IDA | Homo_sapiens(9606) | Process |
GO:0071013 | part_of catalytic step 2 spliceosome | 1 | IDA | Homo_sapiens(9606) | Component |
GO:1990904 | part_of ribonucleoprotein complex | 1 | IBA | Homo_sapiens(9606) | Component |