Ensembl ID ENSG00000169045 Gene ID 3187 Accession 5041
Gene Symbol HNRNPH1 Alias HNRPH;HNRPH1;NEDCDS;hnRNPH Full Name heterogeneous nuclear ribonucleoprotein H1
Position 5 : 179614178 - 179634784 Length 20607 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]

ENSG00000169045 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000169045 HNRNPH1 0.66 1.91e-22 KIRC
ENSG00000169045 HNRNPH1 0.46 6.20e-11 COAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000169045 HNRNPH1 tumor 14980514
ENSG00000169045 HNRNPH1 colon cancer 19425502
ENSG00000169045 HNRNPH1 cancer 20145135
ENSG00000169045 HNRNPH1 tumor 20700505
ENSG00000169045 HNRNPH1 tumor 21194727
ENSG00000169045 HNRNPH1 head and neck cancers 21512137
ENSG00000169045 HNRNPH1 GBM 21915099
ENSG00000169045 HNRNPH1 cancer 22792276
ENSG00000169045 HNRNPH1 cancer 23284676
ENSG00000169045 HNRNPH1 tumour 24045656
ENSG00000169045 HNRNPH1 breast tumor 25264628
ENSG00000169045 HNRNPH1 breast tumors 26930004
ENSG00000169045 HNRNPH1 cancer 27279334
ENSG00000169045 HNRNPH1 tumor 27621578
ENSG00000169045 HNRNPH1 tumour 27940037
ENSG00000169045 HNRNPH1 tumor 29362363
ENSG00000169045 HNRNPH1 cancer 30120239
ENSG00000169045 HNRNPH1 prostate cancer 30939845
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000169045 HNRNPH1 SARC 0.0072 high
ENSG00000169045 HNRNPH1 STAD 0.0015 low
ENSG00000169045 HNRNPH1 PAAD 0.0096 low
ENSG00000169045 HNRNPH1 THCA 0.0035 high
ENSG00000169045 HNRNPH1 HNSC 0.0011 low
ENSG00000169045 HNRNPH1 KICH 0.00014 high
ENSG00000169045 HNRNPH1 PCPG 0.0044 low
ENSG00000169045 HNRNPH1 THYM 0.01 low
ENSG00000169045 HNRNPH1 UCS 0.005 low
ENSG00000169045 HNRNPH1 OV 0.022 low
ENSG00000169045 HNRNPH1 KIRC 0.037 high
ENSG00000169045 HNRNPH1 PRAD 0.017 low
ENSG00000169045 HNRNPH1 BLCA 0.0015 low
ENSG00000169045 HNRNPH1 GBM 0.041 low
ENSG00000169045 HNRNPH1 SKCM 0.00022 low
ENSG00000169045 HNRNPH1 CESC 0.017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000169045 HNRNPH1 LGG Del 3.397304 0.063735 0.406751 0.111111
ENSG00000169045 HNRNPH1 KIRP Amp 0.969852 0.061208 0.634107 0.125000
ENSG00000169045 HNRNPH1 ACC Amp 1.636341 0.378498 1.219810 0.688889
ENSG00000169045 HNRNPH1 SKCM Del 1.747804 0.082895 0.479053 0.297003
ENSG00000169045 HNRNPH1 HNSC Del 1.671364 0.065125 0.392204 0.373563
ENSG00000169045 HNRNPH1 LIHC Amp 1.931368 0.144539 0.563097 0.354054
ENSG00000169045 HNRNPH1 BLCA Del 1.859881 0.096324 0.399768 0.477941
ENSG00000169045 HNRNPH1 KIRC Amp 59.407579 0.324820 0.550725 0.625000