Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2Dengue
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000168906 Gene ID 4144 Accession 6904
Symbol MAT2A Alias MATA2;MATII;SAMS2 Full Name methionine adenosyltransferase 2A
Status Confidence Length 6114 bases Strand Plus strand
Position 2 : 85539168 - 85545281 RNA binding domain N.A.
Summary The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36553579 The Role of the m6A RNA Methyltransferase METTL16 in Gene Expression and SAM Homeostasis. E Jacqueline Mermoud 2022-12-08 Genes
34227247 RNA methyltransferase METTL16: Targets and function. R Emily Satterwhite 2022-03-01 Wiley interdisciplinary reviews. RNA
34780697 Human Mat2A Uses an Ordered Kinetic Mechanism and Is Stabilized but Not Regulated by Mat2B. Jonathan Bailey 2021-11-30 Biochemistry
36794723 Structure of the Caenorhabditis elegans m6A methyltransferase METT10 that regulates SAM homeostasis. Jue Ju 2023-03-21 Nucleic acids research
35155260 Emerging Roles of m6A RNA Methylation Regulators in Gynecological Cancer. Wanjun Huang 2022-01-01 Frontiers in oncology
36584291 Elucidating the Kinetic Mechanism of Human METTL16. Kurtis Breger 2023-01-17 Biochemistry
30197299 Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development. Mateusz Mendel 2018-09-20 Molecular cell
37504262 RNA Methyltransferase METTL16's Protein Domains Have Differential Functional Effects on Cell Processes. S Emily Talic 2023-06-29 Current issues in molecular biology
30197297 Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor. A Katelyn Doxtader 2018-09-20 Molecular cell

Transcripts

Name Transcript ID bp Protein Translation ID
MAT2A-203 ENST00000465151 583 No protein -
MAT2A-204 ENST00000469221 691 No protein -
MAT2A-201 ENST00000306434 2817 395aa ENSP00000303147
MAT2A-205 ENST00000481412 1438 No protein -
MAT2A-202 ENST00000409017 1927 299aa ENSP00000386353
MAT2A-206 ENST00000490878 565 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000168906homo_sapiensENSP0000036128793.670984.3038homo_sapiensENSP0000030314793.670984.3038

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000168906homo_sapiensENSP0000030314794.430494.1772nomascus_leucogenysENSNLEP0000004462096.632196.3731
ENSG00000168906homo_sapiensENSP00000303147100100pan_paniscusENSPPAP00000036801100100
ENSG00000168906homo_sapiensENSP00000303147100100pongo_abeliiENSPPYP00000013638100100
ENSG00000168906homo_sapiensENSP00000303147100100pan_troglodytesENSPTRP00000020815100100
ENSG00000168906homo_sapiensENSP00000303147100100gorilla_gorillaENSGGOP00000004838100100
ENSG00000168906homo_sapiensENSP0000030314797.468495.9494ornithorhynchus_anatinusENSOANP0000003656978.411477.1894
ENSG00000168906homo_sapiensENSP0000030314797.215295.1899sarcophilus_harrisiiENSSHAP0000003634192.753690.8213
ENSG00000168906homo_sapiensENSP0000030314792.405190.8861notamacropus_eugeniiENSMEUP0000000257492.405190.8861
ENSG00000168906homo_sapiensENSP0000030314767.594967.0886choloepus_hoffmanniENSCHOP0000000750698.888998.1481
ENSG00000168906homo_sapiensENSP0000030314798.227997.4684choloepus_hoffmanniENSCHOP0000001237098.227997.4684
ENSG00000168906homo_sapiensENSP0000030314786.329182.5316dasypus_novemcinctusENSDNOP0000002084290.450986.4721
ENSG00000168906homo_sapiensENSP0000030314799.746899.4937erinaceus_europaeusENSEEUP0000000204299.746899.4937
ENSG00000168906homo_sapiensENSP0000030314788.101378.9873echinops_telfairiENSETEP0000001271790.861681.4621
ENSG00000168906homo_sapiensENSP0000030314787.594983.038echinops_telfairiENSETEP0000000504493.766988.8889
ENSG00000168906homo_sapiensENSP0000030314799.240597.7215echinops_telfairiENSETEP0000000620099.240597.7215
ENSG00000168906homo_sapiensENSP00000303147100100callithrix_jacchusENSCJAP00000083858100100
ENSG00000168906homo_sapiensENSP00000303147100100cercocebus_atysENSCATP00000001058100100
ENSG00000168906homo_sapiensENSP0000030314797.974797.2152macaca_fascicularisENSMFAP0000000473393.704692.9782
ENSG00000168906homo_sapiensENSP0000030314797.974797.2152macaca_mulattaENSMMUP0000000593093.704692.9782
ENSG00000168906homo_sapiensENSP0000030314797.974797.2152macaca_nemestrinaENSMNEP0000003888093.704692.9782
ENSG00000168906homo_sapiensENSP0000030314797.974797.2152papio_anubisENSPANP0000001861393.704692.9782
ENSG00000168906homo_sapiensENSP0000030314793.670993.6709mandrillus_leucophaeusENSMLEP0000000940997.368497.3684
ENSG00000168906homo_sapiensENSP0000030314789.367189.1139tursiops_truncatusENSTTRP0000000850489.367189.1139
ENSG00000168906homo_sapiensENSP0000030314797.721596.7089vulpes_vulpesENSVVUP0000000219193.462592.4939
ENSG00000168906homo_sapiensENSP0000030314710099.4937mus_spretusMGP_SPRETEiJ_P007722310099.4937
ENSG00000168906homo_sapiensENSP0000030314797.215295.9494equus_asinusENSEASP0000500184092.978291.7676
ENSG00000168906homo_sapiensENSP0000030314797.721596.4557capra_hircusENSCHIP0000003247193.462592.2518
ENSG00000168906homo_sapiensENSP0000030314799.746899.4937loxodonta_africanaENSLAFP0000001512299.746899.4937
ENSG00000168906homo_sapiensENSP0000030314710099.7468panthera_leoENSPLOP0000000280310099.7468
ENSG00000168906homo_sapiensENSP0000030314797.974796.962ailuropoda_melanoleucaENSAMEP0000000231293.704692.7361
ENSG00000168906homo_sapiensENSP0000030314797.721596.4557bos_indicus_hybridENSBIXP0000500623993.462592.2518
ENSG00000168906homo_sapiensENSP0000030314792.151991.8987oryctolagus_cuniculusENSOCUP0000000204010099.7253
ENSG00000168906homo_sapiensENSP0000030314797.215295.9494equus_caballusENSECAP0000000559492.978291.7676
ENSG00000168906homo_sapiensENSP0000030314797.974796.962canis_lupus_familiarisENSCAFP0084502017293.704692.7361
ENSG00000168906homo_sapiensENSP0000030314710099.7468panthera_pardusENSPPRP0000001412610099.7468
ENSG00000168906homo_sapiensENSP0000030314793.164691.6456marmota_marmota_marmotaENSMMMP0000000906298.659597.0509
ENSG00000168906homo_sapiensENSP0000030314797.721596.2025balaenoptera_musculusENSBMSP0001002441886.547185.2018
ENSG00000168906homo_sapiensENSP0000030314799.493798.481cavia_porcellusENSCPOP0000002879399.493798.481
ENSG00000168906homo_sapiensENSP0000030314799.746899.4937felis_catusENSFCAP0000001110299.746899.4937
ENSG00000168906homo_sapiensENSP0000030314710099.7468ursus_americanusENSUAMP0000003639510099.7468
ENSG00000168906homo_sapiensENSP0000030314797.215295.1899monodelphis_domesticaENSMODP0000001947392.753690.8213
ENSG00000168906homo_sapiensENSP0000030314775.44375.1899bison_bison_bisonENSBBBP0000001182699.665699.3311
ENSG00000168906homo_sapiensENSP0000030314799.746899.2405monodon_monocerosENSMMNP0001500827999.746899.2405
ENSG00000168906homo_sapiensENSP0000030314796.96296.2025sus_scrofaENSSSCP0000005856293.872693.1373
ENSG00000168906homo_sapiensENSP0000030314797.721596.4557microcebus_murinusENSMICP0000001043187.528386.3946
ENSG00000168906homo_sapiensENSP0000030314795.949494.1772octodon_degusENSODEP0000000061899.475197.6378
ENSG00000168906homo_sapiensENSP0000030314765.063364.3038octodon_degusENSODEP0000000417899.612498.4496
ENSG00000168906homo_sapiensENSP0000030314710098.9873jaculus_jaculusENSJJAP0000001877910098.9873
ENSG00000168906homo_sapiensENSP0000030314799.746899.2405ovis_aries_rambouilletENSOARP0002000378599.746899.2405
ENSG00000168906homo_sapiensENSP0000030314798.227997.2152ursus_maritimusENSUMAP0000000850099.232798.2097
ENSG00000168906homo_sapiensENSP0000030314791.898791.6456ochotona_princepsENSOPRP0000000174710099.7245
ENSG00000168906homo_sapiensENSP0000030314799.746899.2405delphinapterus_leucasENSDLEP0000002222999.746899.2405
ENSG00000168906homo_sapiensENSP0000030314799.746899.2405physeter_catodonENSPCTP0000502388999.746899.2405
ENSG00000168906homo_sapiensENSP0000030314799.493798.9873mus_caroliMGP_CAROLIEiJ_P007433499.493798.9873
ENSG00000168906homo_sapiensENSP0000030314710099.4937mus_musculusENSMUSP0000008711810099.4937
ENSG00000168906homo_sapiensENSP0000030314710099.4937dipodomys_ordiiENSDORP0000002603010099.4937
ENSG00000168906homo_sapiensENSP0000030314799.746899.4937mustela_putorius_furoENSMPUP0000000886399.746899.4937
ENSG00000168906homo_sapiensENSP0000030314763.544359.2405aotus_nancymaaeENSANAP0000001760591.272785.0909
ENSG00000168906homo_sapiensENSP00000303147100100aotus_nancymaaeENSANAP00000023101100100
ENSG00000168906homo_sapiensENSP0000030314784.55782.5316saimiri_boliviensis_boliviensisENSSBOP0000001396594.350392.0904
ENSG00000168906homo_sapiensENSP00000303147100100saimiri_boliviensis_boliviensisENSSBOP00000006628100100
ENSG00000168906homo_sapiensENSP0000030314791.898791.6456vicugna_pacosENSVPAP0000000177099.725399.4505
ENSG00000168906homo_sapiensENSP00000303147100100chlorocebus_sabaeusENSCSAP00000012240100100
ENSG00000168906homo_sapiensENSP0000030314777.215276.7089tupaia_belangeriENSTBEP0000000772688.150387.5723
ENSG00000168906homo_sapiensENSP0000030314710099.4937mesocricetus_auratusENSMAUP0000000924510099.4937
ENSG00000168906homo_sapiensENSP0000030314797.721596.4557phocoena_sinusENSPSNP0000001091493.462592.2518
ENSG00000168906homo_sapiensENSP0000030314799.240598.7342camelus_dromedariusENSCDRP0000502376199.492498.9848
ENSG00000168906homo_sapiensENSP0000030314782.531679.4937carlito_syrichtaENSTSYP0000002018993.948190.4899
ENSG00000168906homo_sapiensENSP0000030314774.430472.1519carlito_syrichtaENSTSYP0000001480391.87589.0625
ENSG00000168906homo_sapiensENSP0000030314792.151991.8987carlito_syrichtaENSTSYP0000002814110099.7253
ENSG00000168906homo_sapiensENSP0000030314791.898791.6456panthera_tigris_altaicaENSPTIP0000001419691.898791.6456
ENSG00000168906homo_sapiensENSP0000030314797.721596.4557rattus_norvegicusENSRNOP0000008178397.721596.4557
ENSG00000168906homo_sapiensENSP0000030314799.746898.9873rattus_norvegicusENSRNOP0000009457299.746898.9873
ENSG00000168906homo_sapiensENSP0000030314710099.7468prolemur_simusENSPSMP0000003466010099.7468
ENSG00000168906homo_sapiensENSP0000030314799.746899.4937microtus_ochrogasterENSMOCP0000000366310099.7462
ENSG00000168906homo_sapiensENSP0000030314710099.7468microtus_ochrogasterENSMOCP0000001137210099.7468
ENSG00000168906homo_sapiensENSP0000030314775.696274.4304sorex_araneusENSSARP0000001250487.426985.9649
ENSG00000168906homo_sapiensENSP0000030314784.050683.5443peromyscus_maniculatus_bairdiiENSPEMP0000001585010099.3976
ENSG00000168906homo_sapiensENSP0000030314798.987398.481bos_mutusENSBMUP0000003430499.744999.2347
ENSG00000168906homo_sapiensENSP0000030314786.07684.557mus_spicilegusENSMSIP0000002605092.896291.2568
ENSG00000168906homo_sapiensENSP0000030314710099.4937mus_spicilegusENSMSIP0000000895010099.4937
ENSG00000168906homo_sapiensENSP0000030314710099.4937cricetulus_griseus_chok1gshdENSCGRP0000100766310099.4937
ENSG00000168906homo_sapiensENSP0000030314799.746899.2405pteropus_vampyrusENSPVAP0000001446599.746899.2405
ENSG00000168906homo_sapiensENSP0000030314798.987397.7215myotis_lucifugusENSMLUP0000000488298.987397.7215
ENSG00000168906homo_sapiensENSP0000030314799.240597.7215vombatus_ursinusENSVURP0001001188699.240597.7215
ENSG00000168906homo_sapiensENSP0000030314797.721596.2025rhinolophus_ferrumequinumENSRFEP0001001745193.462592.0097
ENSG00000168906homo_sapiensENSP0000030314799.746899.4937neovison_visonENSNVIP0000002406099.746899.4937
ENSG00000168906homo_sapiensENSP0000030314797.721596.4557bos_taurusENSBTAP0000006140993.462592.2518
ENSG00000168906homo_sapiensENSP0000030314797.721595.6962heterocephalus_glaber_femaleENSHGLP0000003220193.462591.5254
ENSG00000168906homo_sapiensENSP0000030314799.746899.7468rhinopithecus_bietiENSRBIP0000003394599.746899.7468
ENSG00000168906homo_sapiensENSP0000030314710099.7468canis_lupus_dingoENSCAFP0002001836810099.7468
ENSG00000168906homo_sapiensENSP0000030314797.721596.4557sciurus_vulgarisENSSVLP0000502120793.462592.2518
ENSG00000168906homo_sapiensENSP0000030314797.215295.1899phascolarctos_cinereusENSPCIP0000000501792.753690.8213
ENSG00000168906homo_sapiensENSP0000030314710099.4937nannospalax_galiliENSNGAP0000001243110099.4937
ENSG00000168906homo_sapiensENSP0000030314799.746899.2405bos_grunniensENSBGRP0000000928399.746899.2405
ENSG00000168906homo_sapiensENSP0000030314799.746898.481chinchilla_lanigeraENSCLAP0000001042799.746898.481
ENSG00000168906homo_sapiensENSP0000030314797.721596.4557cervus_hanglu_yarkandensisENSCHYP0000001424093.462592.2518
ENSG00000168906homo_sapiensENSP0000030314799.746899.2405catagonus_wagneriENSCWAP0000000511999.746899.2405
ENSG00000168906homo_sapiensENSP0000030314799.746898.9873ictidomys_tridecemlineatusENSSTOP0000000968599.746898.9873
ENSG00000168906homo_sapiensENSP0000030314710099.7468otolemur_garnettiiENSOGAP0000001727110099.7468
ENSG00000168906homo_sapiensENSP00000303147100100cebus_imitatorENSCCAP00000005042100100
ENSG00000168906homo_sapiensENSP0000030314799.746898.9873urocitellus_parryiiENSUPAP0001000010899.746898.9873
ENSG00000168906homo_sapiensENSP0000030314796.708995.1899moschus_moschiferusENSMMSP0000002326792.493991.0412
ENSG00000168906homo_sapiensENSP0000030314799.746899.2405moschus_moschiferusENSMMSP0000001558299.746899.2405
ENSG00000168906homo_sapiensENSP0000030314799.746899.7468rhinopithecus_roxellanaENSRROP0000003132099.746899.7468
ENSG00000168906homo_sapiensENSP0000030314710099.4937mus_pahariMGP_PahariEiJ_P005040410099.4937
ENSG00000168906homo_sapiensENSP0000030314799.240598.9873propithecus_coquereliENSPCOP0000000485699.240598.9873
ENSG00000168906homo_sapiensENSP0000030314782.531671.1392caenorhabditis_elegansC06E7.1a.180.693169.5545
ENSG00000168906homo_sapiensENSP0000030314782.025370.8861caenorhabditis_elegansC06E7.3a.180.19869.3069
ENSG00000168906homo_sapiensENSP0000030314781.772165.0633caenorhabditis_elegansC49F5.1.380.148963.7717
ENSG00000168906homo_sapiensENSP0000030314781.51969.8734caenorhabditis_elegansT13A10.11a.179.70368.3168
ENSG00000168906homo_sapiensENSP0000030314787.341872.9114drosophila_melanogasterFBpp008845084.558870.5882
ENSG00000168906homo_sapiensENSP0000030314786.582372.6582ciona_intestinalisENSCINP0000001671785.571.75
ENSG00000168906homo_sapiensENSP0000030314788.101380.7595eptatretus_burgeriENSEBUP0000000483587.878880.5556
ENSG00000168906homo_sapiensENSP0000030314791.139285.3165callorhinchus_miliiENSCMIP0000002323390.680184.8867
ENSG00000168906homo_sapiensENSP0000030314795.949489.6203latimeria_chalumnaeENSLACP0000000591496.930990.5371
ENSG00000168906homo_sapiensENSP0000030314796.96293.1646lepisosteus_oculatusENSLOCP0000001872096.717292.9293
ENSG00000168906homo_sapiensENSP0000030314795.949488.6076clupea_harengusENSCHAP0000001175492.892285.7843
ENSG00000168906homo_sapiensENSP0000030314794.936785.5696clupea_harengusENSCHAP0000002011792.592683.4568
ENSG00000168906homo_sapiensENSP0000030314788.354482.5316danio_rerioENSDARP0000005396296.143289.8072
ENSG00000168906homo_sapiensENSP0000030314796.96291.8987danio_rerioENSDARP0000010578296.96291.8987
ENSG00000168906homo_sapiensENSP0000030314796.96290.1266carassius_auratusENSCARP0000010940996.717289.899
ENSG00000168906homo_sapiensENSP0000030314796.96291.1392carassius_auratusENSCARP0000001797196.717290.9091
ENSG00000168906homo_sapiensENSP0000030314793.164687.0886carassius_auratusENSCARP0000001637784.403778.8991
ENSG00000168906homo_sapiensENSP0000030314797.721592.6582astyanax_mexicanusENSAMXP0000001914297.721592.6582
ENSG00000168906homo_sapiensENSP0000030314796.455790.1266astyanax_mexicanusENSAMXP0000003163195.2589
ENSG00000168906homo_sapiensENSP0000030314792.658285.0633ictalurus_punctatusENSIPUP0000003607593.606185.9335
ENSG00000168906homo_sapiensENSP0000030314796.202589.3671ictalurus_punctatusENSIPUP0000003054996.202589.3671
ENSG00000168906homo_sapiensENSP0000030314796.202588.8608esox_luciusENSELUP0000004880393.827286.6667
ENSG00000168906homo_sapiensENSP0000030314796.96291.1392esox_luciusENSELUP0000003941596.96291.1392
ENSG00000168906homo_sapiensENSP0000030314796.96291.3924electrophorus_electricusENSEEEP0000005167596.96291.3924
ENSG00000168906homo_sapiensENSP0000030314795.949489.6203electrophorus_electricusENSEEEP0000000886395.707189.3939
ENSG00000168906homo_sapiensENSP0000030314793.92486.5823oncorhynchus_kisutchENSOKIP0000502465992.982585.7143
ENSG00000168906homo_sapiensENSP0000030314795.696288.8608oncorhynchus_kisutchENSOKIP0000500884793.333386.6667
ENSG00000168906homo_sapiensENSP0000030314796.708990.6329oncorhynchus_kisutchENSOKIP0000511490596.708990.6329
ENSG00000168906homo_sapiensENSP0000030314790.126684.3038oncorhynchus_kisutchENSOKIP0000502919487.254981.6176
ENSG00000168906homo_sapiensENSP0000030314797.215290.3797oncorhynchus_mykissENSOMYP0000003450796.969790.1515
ENSG00000168906homo_sapiensENSP0000030314796.708990.6329oncorhynchus_mykissENSOMYP0000010427596.708990.6329
ENSG00000168906homo_sapiensENSP0000030314796.455790.3797oncorhynchus_mykissENSOMYP0000004775996.455790.3797
ENSG00000168906homo_sapiensENSP0000030314793.92486.076oncorhynchus_mykissENSOMYP0000001354492.518784.788
ENSG00000168906homo_sapiensENSP0000030314796.202589.1139salmo_salarENSSSAP0000011149592.909586.0636
ENSG00000168906homo_sapiensENSP0000030314795.949489.8734salmo_salarENSSSAP0000002421088.34582.7506
ENSG00000168906homo_sapiensENSP0000030314792.405185.0633salmo_salarENSSSAP0000002436284.686877.9582
ENSG00000168906homo_sapiensENSP0000030314796.96289.6203salmo_salarENSSSAP0000016583496.717289.3939
ENSG00000168906homo_sapiensENSP0000030314796.708990.3797salmo_truttaENSSTUP0000001453796.708990.3797
ENSG00000168906homo_sapiensENSP0000030314796.96289.6203salmo_truttaENSSTUP0000010336096.717289.3939
ENSG00000168906homo_sapiensENSP0000030314795.696288.8608salmo_truttaENSSTUP0000004681493.333386.6667
ENSG00000168906homo_sapiensENSP0000030314791.392485.3165salmo_truttaENSSTUP0000001728890.93284.8867
ENSG00000168906homo_sapiensENSP0000030314791.392484.0506gadus_morhuaENSGMOP0000005980681.674275.1131
ENSG00000168906homo_sapiensENSP0000030314792.405185.8228gadus_morhuaENSGMOP0000005318389.242182.8851
ENSG00000168906homo_sapiensENSP0000030314793.92488.1013fundulus_heteroclitusENSFHEP0000000077286.885281.4988
ENSG00000168906homo_sapiensENSP0000030314796.455789.6203fundulus_heteroclitusENSFHEP0000003111896.212189.3939
ENSG00000168906homo_sapiensENSP0000030314788.354482.0253poecilia_reticulataENSPREP0000003173996.408889.5028
ENSG00000168906homo_sapiensENSP0000030314795.189988.8608poecilia_reticulataENSPREP0000001570194.949588.6364
ENSG00000168906homo_sapiensENSP0000030314796.96289.6203xiphophorus_maculatusENSXMAP0000001781896.717289.3939
ENSG00000168906homo_sapiensENSP0000030314794.936789.1139xiphophorus_maculatusENSXMAP0000000415894.69788.8889
ENSG00000168906homo_sapiensENSP0000030314796.96291.1392oryzias_latipesENSORLP0000000791396.717290.9091
ENSG00000168906homo_sapiensENSP0000030314793.92488.1013oryzias_latipesENSORLP0000001158094.642988.7755
ENSG00000168906homo_sapiensENSP0000030314794.177287.0886cyclopterus_lumpusENSCLMP0000503776688.782882.1002
ENSG00000168906homo_sapiensENSP0000030314795.949489.6203cyclopterus_lumpusENSCLMP0000501925495.949489.6203
ENSG00000168906homo_sapiensENSP0000030314796.708991.6456oreochromis_niloticusENSONIP0000001675896.464691.4141
ENSG00000168906homo_sapiensENSP0000030314792.658286.8354oreochromis_niloticusENSONIP0000006190989.268383.6585
ENSG00000168906homo_sapiensENSP0000030314788.101382.0253haplochromis_burtoniENSHBUP0000003412490.62584.375
ENSG00000168906homo_sapiensENSP0000030314796.708991.6456haplochromis_burtoniENSHBUP0000002513696.464691.4141
ENSG00000168906homo_sapiensENSP0000030314796.708991.6456astatotilapia_callipteraENSACLP0000003628896.464691.4141
ENSG00000168906homo_sapiensENSP0000030314793.92488.3544astatotilapia_callipteraENSACLP0000002667293.216187.6884
ENSG00000168906homo_sapiensENSP0000030314794.683588.3544sparus_aurataENSSAUP0001006339494.206687.9093
ENSG00000168906homo_sapiensENSP0000030314795.44389.6203sparus_aurataENSSAUP0001001843291.951286.3415
ENSG00000168906homo_sapiensENSP0000030314789.620383.038lates_calcariferENSLCAP0001000986289.168882.6196
ENSG00000168906homo_sapiensENSP0000030314796.708990.6329lates_calcariferENSLCAP0001006079596.464690.404
ENSG00000168906homo_sapiensENSP0000030314798.227993.1646xenopus_tropicalisENSXETP0000008367997.979892.9293
ENSG00000168906homo_sapiensENSP0000030314799.240596.2025chrysemys_picta_belliiENSCPBP0000003317499.240596.2025
ENSG00000168906homo_sapiensENSP0000030314799.240596.4557sphenodon_punctatusENSSPUP0000000484099.240596.4557
ENSG00000168906homo_sapiensENSP0000030314799.240595.9494crocodylus_porosusENSCPRP0000500043499.240595.9494
ENSG00000168906homo_sapiensENSP0000030314795.44388.1013laticauda_laticaudataENSLLTP0000002188296.419489.0026
ENSG00000168906homo_sapiensENSP0000030314795.44387.8481notechis_scutatusENSNSUP0000002287296.419488.7468
ENSG00000168906homo_sapiensENSP0000030314795.44388.3544pseudonaja_textilisENSPTXP0000001810596.419489.2583
ENSG00000168906homo_sapiensENSP0000030314783.544381.7721anas_platyrhynchos_platyrhynchosENSAPLP0000003171399.397697.2892
ENSG00000168906homo_sapiensENSP0000030314791.392489.1139gallus_gallusENSGALP0001002822791.857589.5674
ENSG00000168906homo_sapiensENSP0000030314785.063382.5316serinus_canariaENSSCAP0000002199698.245695.3216
ENSG00000168906homo_sapiensENSP0000030314796.455793.6709parus_majorENSPMJP0000002099569.398967.3953
ENSG00000168906homo_sapiensENSP0000030314795.949489.3671anolis_carolinensisENSACAP0000004084396.930990.2813
ENSG00000168906homo_sapiensENSP0000030314794.177288.6076neolamprologus_brichardiENSNBRP0000000164893.467387.9397
ENSG00000168906homo_sapiensENSP0000030314788.354483.5443neolamprologus_brichardiENSNBRP0000000985196.408891.1602
ENSG00000168906homo_sapiensENSP0000030314795.189988.6076naja_najaENSNNAP0000000705396.163789.5141
ENSG00000168906homo_sapiensENSP0000030314796.708990.1266podarcis_muralisENSPMRP0000001493874.755469.6673
ENSG00000168906homo_sapiensENSP0000030314773.670969.6203geospiza_fortisENSGFOP0000000757982.670578.125
ENSG00000168906homo_sapiensENSP0000030314797.721594.6835erpetoichthys_calabaricusENSECRP0000000052697.474794.4444
ENSG00000168906homo_sapiensENSP0000030314794.936789.6203kryptolebias_marmoratusENSKMAP0000001263994.69789.3939
ENSG00000168906homo_sapiensENSP0000030314796.708990.6329kryptolebias_marmoratusENSKMAP0000002464496.464690.404
ENSG00000168906homo_sapiensENSP0000030314794.430489.1139salvator_merianaeENSSMRP0000002563056.429753.2526
ENSG00000168906homo_sapiensENSP0000030314782.784876.962oryzias_javanicusENSOJAP0000002586182.994977.1574
ENSG00000168906homo_sapiensENSP0000030314796.455790.3797oryzias_javanicusENSOJAP0000003454296.212190.1515
ENSG00000168906homo_sapiensENSP0000030314789.113981.7721amphilophus_citrinellusENSACIP0000002408490.956183.4625
ENSG00000168906homo_sapiensENSP0000030314788.354483.7975amphilophus_citrinellusENSACIP0000000145696.408891.4365
ENSG00000168906homo_sapiensENSP0000030314793.92488.6076dicentrarchus_labraxENSDLAP0000503341488.544283.5322
ENSG00000168906homo_sapiensENSP0000030314795.189989.6203dicentrarchus_labraxENSDLAP0000505941693.300287.8412
ENSG00000168906homo_sapiensENSP0000030314790.126682.7848amphiprion_perculaENSAPEP0000001317688.337581.1414
ENSG00000168906homo_sapiensENSP0000030314796.708991.3924amphiprion_perculaENSAPEP0000003447596.464691.1616
ENSG00000168906homo_sapiensENSP0000030314795.696289.8734oryzias_sinensisENSOSIP0000003819894.736888.9724
ENSG00000168906homo_sapiensENSP0000030314793.92488.1013oryzias_sinensisENSOSIP0000002805794.642988.7755
ENSG00000168906homo_sapiensENSP0000030314781.772178.7342pelodiscus_sinensisENSPSIP0000001560182.820579.7436
ENSG00000168906homo_sapiensENSP0000030314799.240596.4557gopherus_evgoodeiENSGEVP0000500185499.240596.4557
ENSG00000168906homo_sapiensENSP0000030314799.240596.4557chelonoidis_abingdoniiENSCABP0000001638699.240596.4557
ENSG00000168906homo_sapiensENSP0000030314795.949490.3797seriola_dumeriliENSSDUP0000002361795.707190.1515
ENSG00000168906homo_sapiensENSP0000030314796.455791.1392seriola_dumeriliENSSDUP0000002767296.212190.9091
ENSG00000168906homo_sapiensENSP0000030314795.189989.1139cottoperca_gobioENSCGOP0000003612993.300287.3449
ENSG00000168906homo_sapiensENSP0000030314793.92487.3418cottoperca_gobioENSCGOP0000001241093.450986.9018
ENSG00000168906homo_sapiensENSP0000030314773.670971.8987struthio_camelus_australisENSSCUP0000001975398.310895.9459
ENSG00000168906homo_sapiensENSP0000030314793.417790.8861anser_brachyrhynchusENSABRP0000000070395.844293.2467
ENSG00000168906homo_sapiensENSP0000030314793.92487.0886gasterosteus_aculeatusENSGACP0000002266493.686986.8687
ENSG00000168906homo_sapiensENSP0000030314796.202589.8734gasterosteus_aculeatusENSGACP0000001110996.202589.8734
ENSG00000168906homo_sapiensENSP0000030314794.683587.3418cynoglossus_semilaevisENSCSEP0000000264194.444487.1212
ENSG00000168906homo_sapiensENSP0000030314795.189989.1139poecilia_formosaENSPFOP0000001986494.949588.8889
ENSG00000168906homo_sapiensENSP0000030314796.96290.1266poecilia_formosaENSPFOP0000001054696.717289.899
ENSG00000168906homo_sapiensENSP0000030314796.96290.1266poecilia_formosaENSPFOP0000001046196.717289.899
ENSG00000168906homo_sapiensENSP0000030314795.949490.8861myripristis_murdjanENSMMDP0000500803695.949490.8861
ENSG00000168906homo_sapiensENSP0000030314789.367184.3038myripristis_murdjanENSMMDP0000503734583.649378.91
ENSG00000168906homo_sapiensENSP0000030314795.189989.3671sander_luciopercaENSSLUP0000001743789.523884.0476
ENSG00000168906homo_sapiensENSP0000030314793.417786.5823sander_luciopercaENSSLUP0000004776388.489282.0144
ENSG00000168906homo_sapiensENSP0000030314798.734296.962strigops_habroptilaENSSHBP0000500772798.734296.962
ENSG00000168906homo_sapiensENSP0000030314796.708991.3924amphiprion_ocellarisENSAOCP0000003167296.464691.1616
ENSG00000168906homo_sapiensENSP0000030314795.189989.6203amphiprion_ocellarisENSAOCP0000002096594.949589.3939
ENSG00000168906homo_sapiensENSP0000030314799.240596.4557terrapene_carolina_triunguisENSTMTP0000000067699.240596.4557
ENSG00000168906homo_sapiensENSP0000030314799.240596.4557terrapene_carolina_triunguisENSTMTP0000000422499.240596.4557
ENSG00000168906homo_sapiensENSP0000030314752.658247.5949hucho_huchoENSHHUP0000002277987.029378.6611
ENSG00000168906homo_sapiensENSP0000030314796.96289.1139hucho_huchoENSHHUP0000009165696.717288.8889
ENSG00000168906homo_sapiensENSP0000030314797.215290.1266hucho_huchoENSHHUP0000004923696.969789.899
ENSG00000168906homo_sapiensENSP0000030314796.708990.6329hucho_huchoENSHHUP0000005742096.708990.6329
ENSG00000168906homo_sapiensENSP0000030314793.417786.076betta_splendensENSBSLP000000385749082.9268
ENSG00000168906homo_sapiensENSP0000030314794.936789.1139betta_splendensENSBSLP0000002706487.82282.4356
ENSG00000168906homo_sapiensENSP0000030314796.202591.1392pygocentrus_nattereriENSPNAP0000001291795.959690.9091
ENSG00000168906homo_sapiensENSP0000030314797.215291.8987pygocentrus_nattereriENSPNAP0000002462497.215291.8987
ENSG00000168906homo_sapiensENSP0000030314794.683588.8608anabas_testudineusENSATEP0000002458394.444488.6364
ENSG00000168906homo_sapiensENSP0000030314794.936789.1139anabas_testudineusENSATEP0000001620193.98588.2206
ENSG00000168906homo_sapiensENSP0000030314778.48165.5696ciona_savignyiENSCSAVP0000000042176.543263.9506
ENSG00000168906homo_sapiensENSP0000030314781.012765.5696saccharomyces_cerevisiaeYLR180W83.769667.801
ENSG00000168906homo_sapiensENSP0000030314782.025365.3165saccharomyces_cerevisiaeYDR502C84.37567.1875
ENSG00000168906homo_sapiensENSP0000030314788.101383.2911seriola_lalandi_dorsalisENSSLDP0000002182796.132690.884
ENSG00000168906homo_sapiensENSP0000030314795.949490.3797seriola_lalandi_dorsalisENSSLDP0000002135495.707190.1515
ENSG00000168906homo_sapiensENSP0000030314792.911488.1013labrus_bergyltaENSLBEP0000001771995.822590.8616
ENSG00000168906homo_sapiensENSP0000030314794.683588.1013labrus_bergyltaENSLBEP0000002980194.444487.8788
ENSG00000168906homo_sapiensENSP0000030314796.708991.6456pundamilia_nyerereiENSPNYP0000001950496.464691.4141
ENSG00000168906homo_sapiensENSP0000030314788.354482.7848pundamilia_nyerereiENSPNYP0000001438594.070188.1402
ENSG00000168906homo_sapiensENSP0000030314796.708991.6456mastacembelus_armatusENSMAMP0000006837896.464691.4141
ENSG00000168906homo_sapiensENSP0000030314793.92486.076mastacembelus_armatusENSMAMP0000003674190.048582.5243
ENSG00000168906homo_sapiensENSP0000030314796.455791.3924stegastes_partitusENSSPAP0000003128396.212191.1616
ENSG00000168906homo_sapiensENSP0000030314795.189990.1266stegastes_partitusENSSPAP0000002880694.949589.899
ENSG00000168906homo_sapiensENSP0000030314797.215290.3797oncorhynchus_tshawytschaENSOTSP0000505807396.969790.1515
ENSG00000168906homo_sapiensENSP0000030314796.708989.1139oncorhynchus_tshawytschaENSOTSP0000501629996.464688.8889
ENSG00000168906homo_sapiensENSP0000030314796.708990.6329oncorhynchus_tshawytschaENSOTSP0000507912396.708990.6329
ENSG00000168906homo_sapiensENSP0000030314796.708989.1139oncorhynchus_tshawytschaENSOTSP0000508560796.464688.8889
ENSG00000168906homo_sapiensENSP0000030314795.44389.3671oncorhynchus_tshawytschaENSOTSP0000505744595.44389.3671
ENSG00000168906homo_sapiensENSP0000030314795.696289.3671acanthochromis_polyacanthusENSAPOP0000001885195.454589.1414
ENSG00000168906homo_sapiensENSP0000030314796.708991.1392acanthochromis_polyacanthusENSAPOP0000001158596.464690.9091
ENSG00000168906homo_sapiensENSP0000030314799.240597.4684aquila_chrysaetos_chrysaetosENSACCP0002000941899.240597.4684
ENSG00000168906homo_sapiensENSP0000030314793.92488.3544nothobranchius_furzeriENSNFUP0001503795089.830584.5036
ENSG00000168906homo_sapiensENSP0000030314794.177287.0886nothobranchius_furzeriENSNFUP0001505023990.731783.9024
ENSG00000168906homo_sapiensENSP0000030314797.215290.3797cyprinodon_variegatusENSCVAP0000001928596.969790.1515
ENSG00000168906homo_sapiensENSP0000030314794.430488.3544cyprinodon_variegatusENSCVAP0000000500394.191988.1313
ENSG00000168906homo_sapiensENSP0000030314797.215291.6456denticeps_clupeoidesENSDCDP0000003757396.969791.4141
ENSG00000168906homo_sapiensENSP0000030314793.417787.8481larimichthys_croceaENSLCRP0000504101591.111185.679
ENSG00000168906homo_sapiensENSP0000030314796.708990.6329larimichthys_croceaENSLCRP0000500121788.631183.0626
ENSG00000168906homo_sapiensENSP0000030314793.417784.557takifugu_rubripesENSTRUP0000005725093.181884.3434
ENSG00000168906homo_sapiensENSP0000030314796.202590.1266takifugu_rubripesENSTRUP0000006772196.202590.1266
ENSG00000168906homo_sapiensENSP0000030314798.48195.9494ficedula_albicollisENSFALP0000002652998.48195.9494
ENSG00000168906homo_sapiensENSP0000030314794.936787.8481hippocampus_comesENSHCOP0000000743394.69787.6263
ENSG00000168906homo_sapiensENSP0000030314796.708990.8861hippocampus_comesENSHCOP0000002293596.464690.6566
ENSG00000168906homo_sapiensENSP0000030314790.379784.3038cyprinus_carpio_carpioENSCCRP0000012319491.071484.949
ENSG00000168906homo_sapiensENSP0000030314792.151984.557cyprinus_carpio_carpioENSCCRP0000010530592.151984.557
ENSG00000168906homo_sapiensENSP0000030314796.455789.6203cyprinus_carpio_carpioENSCCRP0000010558180.720375
ENSG00000168906homo_sapiensENSP0000030314796.96290.8861cyprinus_carpio_carpioENSCCRP0000012199696.96290.8861
ENSG00000168906homo_sapiensENSP0000030314782.025376.7089coturnix_japonicaENSCJPP0000501401890.250784.4011
ENSG00000168906homo_sapiensENSP0000030314795.189989.1139poecilia_latipinnaENSPLAP0000002461594.949588.8889
ENSG00000168906homo_sapiensENSP0000030314788.101381.7721poecilia_latipinnaENSPLAP0000002329595.867888.9807
ENSG00000168906homo_sapiensENSP0000030314796.708989.6203sinocyclocheilus_grahamiENSSGRP0000005842596.464689.3939
ENSG00000168906homo_sapiensENSP0000030314766.835461.519sinocyclocheilus_grahamiENSSGRP0000005080094.96487.4101
ENSG00000168906homo_sapiensENSP0000030314796.96290.6329sinocyclocheilus_grahamiENSSGRP0000007915596.96290.6329
ENSG00000168906homo_sapiensENSP0000030314796.96290.3797sinocyclocheilus_grahamiENSSGRP0000006677096.717290.1515
ENSG00000168906homo_sapiensENSP0000030314793.92488.3544maylandia_zebraENSMZEP0000502426093.216187.6884
ENSG00000168906homo_sapiensENSP0000030314795.189989.3671maylandia_zebraENSMZEP0000500057495.189989.3671
ENSG00000168906homo_sapiensENSP0000030314796.202590.3797tetraodon_nigroviridisENSTNIP0000001892596.446790.6091
ENSG00000168906homo_sapiensENSP0000030314791.898785.8228tetraodon_nigroviridisENSTNIP0000001197091.666785.6061
ENSG00000168906homo_sapiensENSP0000030314797.721593.924paramormyrops_kingsleyaeENSPKIP0000004089297.474793.6869
ENSG00000168906homo_sapiensENSP0000030314798.227993.6709scleropages_formosusENSSFOP0001500233897.979893.4343
ENSG00000168906homo_sapiensENSP0000030314797.721593.4177leptobrachium_leishanenseENSLLEP0000000731897.474793.1818
ENSG00000168906homo_sapiensENSP0000030314794.177286.3291scophthalmus_maximusENSSMAP0000006722190.072682.5666
ENSG00000168906homo_sapiensENSP0000030314795.44390.1266scophthalmus_maximusENSSMAP0000002675590.407785.3717
ENSG00000168906homo_sapiensENSP0000030314793.417788.1013oryzias_melastigmaENSOMEP0000002233994.132788.7755
ENSG00000168906homo_sapiensENSP0000030314796.708991.3924oryzias_melastigmaENSOMEP0000002230796.464691.1616

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0004478enables methionine adenosyltransferase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005829is_active_in cytosol2IBA,TASHomo_sapiens(9606)Component
GO:0006556involved_in S-adenosylmethionine biosynthetic process3IBA,IDA,IEAHomo_sapiens(9606)Process
GO:0006730involved_in one-carbon metabolic process1IEAHomo_sapiens(9606)Process
GO:0034214involved_in protein hexamerization1IDAHomo_sapiens(9606)Process
GO:0036094enables small molecule binding1EXPHomo_sapiens(9606)Function
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0048269part_of methionine adenosyltransferase complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0051291involved_in protein heterooligomerization1IDAHomo_sapiens(9606)Process
GO:1990830involved_in cellular response to leukemia inhibitory factor1IEAHomo_sapiens(9606)Process

Expression