Ensembl ID ENSG00000168906 Gene ID 4144 Accession 6904
Gene Symbol MAT2A Alias MATA2;MATII;SAMS2 Full Name methionine adenosyltransferase 2A
Position 2 : 85539168 - 85545281 Length 6114 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]

ENSG00000168906 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000168906 MAT2A -1.7 2.95e-30 BLCA
ENSG00000168906 MAT2A -1.0 1.48e-14 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000168906 MAT2A liver cancer 10216131
ENSG00000168906 MAT2A liver cancer 10627284
ENSG00000168906 MAT2A liver cancer 10677369
ENSG00000168906 MAT2A cancer 11208539
ENSG00000168906 MAT2A cancer 11427482
ENSG00000168906 MAT2A cancer 12671891
ENSG00000168906 MAT2A cancer 14530285
ENSG00000168906 MAT2A tumor 14578171
ENSG00000168906 MAT2A breast cancer 15492278
ENSG00000168906 MAT2A neuroendocrine tumors 16517981
ENSG00000168906 MAT2A liver cancer 17441811
ENSG00000168906 MAT2A colon cancer 17631143
ENSG00000168906 MAT2A cancer 18095270
ENSG00000168906 MAT2A cancer 18336669
ENSG00000168906 MAT2A hepatic cancer 19025580
ENSG00000168906 MAT2A liver cancer 20043323
ENSG00000168906 MAT2A cancer 21247894
ENSG00000168906 MAT2A colon cancer 21406062
ENSG00000168906 MAT2A liver cancer 21460102
ENSG00000168906 MAT2A gastric cancer 22542325
ENSG00000168906 MAT2A cancers 23363077
ENSG00000168906 MAT2A colon cancer 23588207
ENSG00000168906 MAT2A tumor 24098708
ENSG00000168906 MAT2A cancers 24636201
ENSG00000168906 MAT2A cancers 24790682
ENSG00000168906 MAT2A colorectal cancers 24950374
ENSG00000168906 MAT2A cancer 24979717
ENSG00000168906 MAT2A cancer 25724580
ENSG00000168906 MAT2A tumor 25900080
ENSG00000168906 MAT2A hepatocellular cancer 25925782
ENSG00000168906 MAT2A colon cancer 26416353
ENSG00000168906 MAT2A cancer 26418898
ENSG00000168906 MAT2A Cancer 27068473
ENSG00000168906 MAT2A cancer 28316886
ENSG00000168906 MAT2A tumor 28496150
ENSG00000168906 MAT2A tumor 28839175
ENSG00000168906 MAT2A tumor 28880543
ENSG00000168906 MAT2A pancreatic cancer 29108270
ENSG00000168906 MAT2A tumor 29141455
ENSG00000168906 MAT2A cancer 29170720
ENSG00000168906 MAT2A tumor 29448301
ENSG00000168906 MAT2A liver tumors 29733835
ENSG00000168906 MAT2A cancer 29749642
ENSG00000168906 MAT2A cancer 29983885
ENSG00000168906 MAT2A prostate cancer 30271587
ENSG00000168906 MAT2A cancer 30591370
ENSG00000168906 MAT2A cancer 30712196
ENSG00000168906 MAT2A colon cancer 30854099
ENSG00000168906 MAT2A tumor 31058319
ENSG00000168906 MAT2A cancer 31061538
ENSG00000168906 MAT2A tumor 31073374
ENSG00000168906 MAT2A cancer 31234428
ENSG00000168906 MAT2A liver cancer 31496615
ENSG00000168906 MAT2A breast cancer 31534156
ENSG00000168906 MAT2A liver cancer 9537246
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000168906 MAT2A MESO 0.02 high
ENSG00000168906 MAT2A THCA 0.039 low
ENSG00000168906 MAT2A LGG 0.0071 high
ENSG00000168906 MAT2A HNSC 0.0057 low
ENSG00000168906 MAT2A READ 0.0011 low
ENSG00000168906 MAT2A KICH 0.0088 high
ENSG00000168906 MAT2A LUAD 0.00028 low
ENSG00000168906 MAT2A BRCA 0.0014 high
ENSG00000168906 MAT2A OV 0.027 high
ENSG00000168906 MAT2A PRAD 0.0054 high
ENSG00000168906 MAT2A BLCA 0.026 low
ENSG00000168906 MAT2A LAML 0.018 low
ENSG00000168906 MAT2A GBM 0.023 high
ENSG00000168906 MAT2A SKCM 0.0018 high
ENSG00000168906 MAT2A CESC 0.023 high
ENSG00000168906 MAT2A LIHC 0.00033 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000168906 MAT2A SARC Amp 0.703232 0.258823 0.576037 0.245136