Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000168517 Gene ID 124790 Accession 28591
Symbol HEXIM2 Alias L3 Full Name HEXIM P-TEFb complex subunit 2
Status Confidence Length 9341 bases Strand Plus strand
Position 17 : 45160700 - 45170040 RNA binding domain HEXIM
Summary This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000302276 HEXIM PF15313 2.4e-45 1
ENSP00000464807 HEXIM PF15313 2.4e-45 1
ENSP00000465086 HEXIM PF15313 2.4e-45 1
ENSP00000465727 HEXIM PF15313 2.4e-45 1
ENSP00000466200 HEXIM PF15313 2.4e-45 1
ENSP00000467517 HEXIM PF15313 2.4e-45 1
ENSP00000468251 HEXIM PF15313 2.4e-45 1
ENSP00000468773 HEXIM PF15313 2.4e-45 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
20144199 EBV-positive Hodgkin lymphoma is associated with suppression of p21cip1/waf1 and a worse prognosis. Ting-Yun Liu 2010-02-09 Molecular cancer
17709395 The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes. Charlotte Barrandon 2007-10-01 Molecular and cellular biology
28082395 The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK. Denise Martinez-Zapien 2017-04-07 Nucleic acids research

Transcripts

Name Transcript ID bp Protein Translation ID
HEXIM2-201 ENST00000307275 1528 286aa ENSP00000302276
HEXIM2-202 ENST00000585340 1345 286aa ENSP00000468251
HEXIM2-208 ENST00000593138 1302 286aa ENSP00000468773
HEXIM2-203 ENST00000586681 1438 286aa ENSP00000465086
HEXIM2-204 ENST00000589230 1436 286aa ENSP00000466200
HEXIM2-206 ENST00000591576 1176 286aa ENSP00000465727
HEXIM2-205 ENST00000591070 1323 286aa ENSP00000464807
HEXIM2-207 ENST00000592695 1246 286aa ENSP00000467517

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
37592Platelet Function Tests1.7277700E-005-
37593Platelet Function Tests1.4751800E-005-
37605Platelet Function Tests1.9382200E-005-
54057Cholesterol, LDL2.4430000E-005-
59530Blood Pressure4.7414877E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000168517homo_sapiensENSP0000032877344.289735.0975homo_sapiensENSP0000046620055.594444.0559

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000168517homo_sapiensENSP0000046620098.601498.2517nomascus_leucogenysENSNLEP0000003174898.601498.2517
ENSG00000168517homo_sapiensENSP00000466200100100pan_paniscusENSPPAP00000002188100100
ENSG00000168517homo_sapiensENSP0000046620094.405692.6573pongo_abeliiENSPPYP0000003046784.905783.3333
ENSG00000168517homo_sapiensENSP00000466200100100pan_troglodytesENSPTRP00000015808100100
ENSG00000168517homo_sapiensENSP00000466200100100gorilla_gorillaENSGGOP0000000774884.365884.3658
ENSG00000168517homo_sapiensENSP0000046620064.685355.9441sarcophilus_harrisiiENSSHAP0000001290276.763566.39
ENSG00000168517homo_sapiensENSP0000046620088.811283.2168dasypus_novemcinctusENSDNOP0000000692186.394680.9524
ENSG00000168517homo_sapiensENSP0000046620084.265776.5734erinaceus_europaeusENSEEUP0000000477086.071478.2143
ENSG00000168517homo_sapiensENSP0000046620080.069973.7762echinops_telfairiENSETEP0000001503487.739580.8429
ENSG00000168517homo_sapiensENSP0000046620094.755291.2587callithrix_jacchusENSCJAP0000004087594.755291.2587
ENSG00000168517homo_sapiensENSP0000046620095.454592.6573callithrix_jacchusENSCJAP0000006447495.454592.6573
ENSG00000168517homo_sapiensENSP0000046620095.454592.6573callithrix_jacchusENSCJAP0000004101495.454592.6573
ENSG00000168517homo_sapiensENSP0000046620098.601496.8531cercocebus_atysENSCATP0000002217598.947497.193
ENSG00000168517homo_sapiensENSP0000046620098.601497.5524macaca_fascicularisENSMFAP0000001959398.601497.5524
ENSG00000168517homo_sapiensENSP0000046620098.601497.5524macaca_mulattaENSMMUP0000007457583.185882.3009
ENSG00000168517homo_sapiensENSP0000046620098.601497.5524macaca_nemestrinaENSMNEP0000001614483.185882.3009
ENSG00000168517homo_sapiensENSP0000046620098.601497.2028papio_anubisENSPANP0000002083198.601497.2028
ENSG00000168517homo_sapiensENSP0000046620098.601497.2028mandrillus_leucophaeusENSMLEP0000002846498.601497.2028
ENSG00000168517homo_sapiensENSP0000046620088.461584.2657tursiops_truncatusENSTTRP0000000594489.399385.159
ENSG00000168517homo_sapiensENSP0000046620089.860184.965vulpes_vulpesENSVVUP0000002503987.41582.6531
ENSG00000168517homo_sapiensENSP0000046620082.867176.5734mus_spretusMGP_SPRETEiJ_P003180975.718869.968
ENSG00000168517homo_sapiensENSP0000046620072.377666.0839equus_asinusENSEASP0000503499289.224181.4655
ENSG00000168517homo_sapiensENSP0000046620086.713379.3706capra_hircusENSCHIP0000000272386.111178.8194
ENSG00000168517homo_sapiensENSP0000046620086.363678.6713loxodonta_africanaENSLAFP0000001230288.530580.6452
ENSG00000168517homo_sapiensENSP0000046620085.314778.6713panthera_leoENSPLOP0000001104181.879275.5034
ENSG00000168517homo_sapiensENSP0000046620083.566479.3706ailuropoda_melanoleucaENSAMEP0000001944987.867683.4559
ENSG00000168517homo_sapiensENSP0000046620087.412681.1189bos_indicus_hybridENSBIXP0000502154686.805680.5556
ENSG00000168517homo_sapiensENSP0000046620085.314779.021oryctolagus_cuniculusENSOCUP0000000583580.794774.8344
ENSG00000168517homo_sapiensENSP0000046620073.776267.1329equus_caballusENSECAP0000007739089.029581.0127
ENSG00000168517homo_sapiensENSP0000046620088.461583.2168canis_lupus_familiarisENSCAFP0084500849388.771983.5088
ENSG00000168517homo_sapiensENSP0000046620088.461583.2168panthera_pardusENSPPRP0000000614788.461583.2168
ENSG00000168517homo_sapiensENSP0000046620088.111982.5175marmota_marmota_marmotaENSMMMP0000000276888.111982.5175
ENSG00000168517homo_sapiensENSP0000046620075.524572.3776balaenoptera_musculusENSBMSP0001002459991.525487.7119
ENSG00000168517homo_sapiensENSP0000046620085.664378.3217felis_catusENSFCAP0000002326483.904176.7123
ENSG00000168517homo_sapiensENSP0000046620087.062982.1678ursus_americanusENSUAMP0000003134887.062982.1678
ENSG00000168517homo_sapiensENSP0000046620061.188852.7972monodelphis_domesticaENSMODP0000003261572.016562.1399
ENSG00000168517homo_sapiensENSP0000046620087.412681.1189bison_bison_bisonENSBBBP0000002465486.805680.5556
ENSG00000168517homo_sapiensENSP0000046620088.811284.965monodon_monocerosENSMMNP0001502428489.436685.5634
ENSG00000168517homo_sapiensENSP0000046620089.510584.2657sus_scrofaENSSSCP0000004204887.37282.2526
ENSG00000168517homo_sapiensENSP0000046620091.95887.4126microcebus_murinusENSMICP0000004185291.95887.4126
ENSG00000168517homo_sapiensENSP0000046620082.517575.5245jaculus_jaculusENSJJAP0000001710677.124270.5882
ENSG00000168517homo_sapiensENSP0000046620087.062979.7203ovis_aries_rambouilletENSOARP0002003330886.458379.1667
ENSG00000168517homo_sapiensENSP0000046620078.671374.1259ursus_maritimusENSUMAP0000001979584.586579.6992
ENSG00000168517homo_sapiensENSP0000046620080.069973.0769ochotona_princepsENSOPRP0000001130181.205774.1135
ENSG00000168517homo_sapiensENSP0000046620084.615480.7692delphinapterus_leucasENSDLEP0000000900385.815681.9149
ENSG00000168517homo_sapiensENSP0000046620089.160884.965physeter_catodonENSPCTP0000501991064.070461.0553
ENSG00000168517homo_sapiensENSP0000046620083.566476.5734mus_caroliMGP_CAROLIEiJ_P003036877.346370.8738
ENSG00000168517homo_sapiensENSP0000046620083.216876.9231mus_musculusENSMUSP0000005367876.038370.2875
ENSG00000168517homo_sapiensENSP0000046620083.216876.9231dipodomys_ordiiENSDORP0000001385982.926876.6551
ENSG00000168517homo_sapiensENSP0000046620088.811282.5175mustela_putorius_furoENSMPUP0000000857881.150275.3994
ENSG00000168517homo_sapiensENSP0000046620095.104991.958aotus_nancymaaeENSANAP0000003372995.104991.958
ENSG00000168517homo_sapiensENSP0000046620096.503594.0559saimiri_boliviensis_boliviensisENSSBOP0000000971796.503594.0559
ENSG00000168517homo_sapiensENSP0000046620098.601497.5524chlorocebus_sabaeusENSCSAP0000000004798.601497.5524
ENSG00000168517homo_sapiensENSP0000046620051.398648.2517tupaia_belangeriENSTBEP0000000924351.398648.2517
ENSG00000168517homo_sapiensENSP0000046620084.615476.5734mesocricetus_auratusENSMAUP0000002506277.564170.1923
ENSG00000168517homo_sapiensENSP0000046620089.160884.6154phocoena_sinusENSPSNP0000002791689.788785.2113
ENSG00000168517homo_sapiensENSP0000046620083.916179.021camelus_dromedariusENSCDRP0000500700384.210579.2982
ENSG00000168517homo_sapiensENSP0000046620081.468574.4755carlito_syrichtaENSTSYP0000001526983.214376.0714
ENSG00000168517homo_sapiensENSP0000046620088.461583.2168panthera_tigris_altaicaENSPTIP0000002239688.461583.2168
ENSG00000168517homo_sapiensENSP0000046620081.818276.2238rattus_norvegicusENSRNOP0000005203974.760469.6486
ENSG00000168517homo_sapiensENSP0000046620091.95888.1119prolemur_simusENSPSMP0000002138091.95888.1119
ENSG00000168517homo_sapiensENSP0000046620084.265776.5734microtus_ochrogasterENSMOCP0000000756076.996869.968
ENSG00000168517homo_sapiensENSP0000046620058.741354.1958sorex_araneusENSSARP0000000716564.367859.387
ENSG00000168517homo_sapiensENSP0000046620083.216875.1748peromyscus_maniculatus_bairdiiENSPEMP0000000155676.038368.6901
ENSG00000168517homo_sapiensENSP0000046620087.412681.1189bos_mutusENSBMUP0000000197086.805680.5556
ENSG00000168517homo_sapiensENSP0000046620083.566476.9231mus_spicilegusENSMSIP0000003310976.357870.2875
ENSG00000168517homo_sapiensENSP0000046620084.96577.2727cricetulus_griseus_chok1gshdENSCGRP0000101379277.635870.607
ENSG00000168517homo_sapiensENSP0000046620080.769276.2238pteropus_vampyrusENSPVAP0000001236687.582.5758
ENSG00000168517homo_sapiensENSP0000046620084.265776.5734myotis_lucifugusENSMLUP0000000507081.972874.4898
ENSG00000168517homo_sapiensENSP0000046620062.937153.4965vombatus_ursinusENSVURP0001001160773.469462.449
ENSG00000168517homo_sapiensENSP0000046620085.314778.3217rhinolophus_ferrumequinumENSRFEP0001001035985.314778.3217
ENSG00000168517homo_sapiensENSP0000046620088.811283.2168neovison_visonENSNVIP0000002957086.689481.2287
ENSG00000168517homo_sapiensENSP0000046620087.412681.1189bos_taurusENSBTAP0000007303586.805680.5556
ENSG00000168517homo_sapiensENSP0000046620098.95198.2517rhinopithecus_bietiENSRBIP0000003635691.883191.2338
ENSG00000168517homo_sapiensENSP0000046620086.713381.4685canis_lupus_dingoENSCAFP0002001181586.713381.4685
ENSG00000168517homo_sapiensENSP0000046620086.713381.1189sciurus_vulgarisENSSVLP0000500709686.713381.1189
ENSG00000168517homo_sapiensENSP0000046620067.832259.0909phascolarctos_cinereusENSPCIP0000001975162.379454.3408
ENSG00000168517homo_sapiensENSP0000046620071.678359.0909procavia_capensisENSPCAP0000001477573.476760.5735
ENSG00000168517homo_sapiensENSP0000046620084.265776.9231nannospalax_galiliENSNGAP0000000568076.265869.6203
ENSG00000168517homo_sapiensENSP0000046620087.412681.1189bos_grunniensENSBGRP0000003820486.805680.5556
ENSG00000168517homo_sapiensENSP0000046620076.573469.2308cervus_hanglu_yarkandensisENSCHYP0000000407779.347871.7391
ENSG00000168517homo_sapiensENSP0000046620090.559486.3636catagonus_wagneriENSCWAP0000000759888.395984.3003
ENSG00000168517homo_sapiensENSP0000046620087.412681.1189ictidomys_tridecemlineatusENSSTOP0000003054287.412681.1189
ENSG00000168517homo_sapiensENSP0000046620090.559487.0629otolemur_garnettiiENSOGAP0000000833190.877287.3684
ENSG00000168517homo_sapiensENSP0000046620096.503593.7063cebus_imitatorENSCCAP0000003657796.503593.7063
ENSG00000168517homo_sapiensENSP0000046620088.461581.8182urocitellus_parryiiENSUPAP0001000152188.461581.8182
ENSG00000168517homo_sapiensENSP0000046620084.615476.5734moschus_moschiferusENSMMSP0000002866185.512477.3852
ENSG00000168517homo_sapiensENSP0000046620098.95198.2517rhinopithecus_roxellanaENSRROP0000003713991.883191.2338
ENSG00000168517homo_sapiensENSP0000046620082.167875.8741mus_pahariMGP_PahariEiJ_P003708775.079969.3291
ENSG00000168517homo_sapiensENSP0000046620092.657388.4615propithecus_coquereliENSPCOP0000000283292.657388.4615
ENSG00000168517homo_sapiensENSP0000046620035.664323.0769drosophila_melanogasterFBpp008242728.333318.3333
ENSG00000168517homo_sapiensENSP0000046620044.405634.6154petromyzon_marinusENSPMAP0000000379658.256945.4128
ENSG00000168517homo_sapiensENSP0000046620044.405632.1678eptatretus_burgeriENSEBUP0000001913643.793131.7241
ENSG00000168517homo_sapiensENSP0000046620052.797238.1119callorhinchus_miliiENSCMIP0000001517947.634134.3849
ENSG00000168517homo_sapiensENSP0000046620042.307731.4685latimeria_chalumnaeENSLACP0000000411755.251141.0959
ENSG00000168517homo_sapiensENSP0000046620046.153835.3147latimeria_chalumnaeENSLACP0000000373367.346951.5306
ENSG00000168517homo_sapiensENSP0000046620055.244842.3077lepisosteus_oculatusENSLOCP0000002161647.023836.0119
ENSG00000168517homo_sapiensENSP0000046620054.195840.9091clupea_harengusENSCHAP0000004175344.412633.5244
ENSG00000168517homo_sapiensENSP0000046620051.04939.1608danio_rerioENSDARP0000005300245.76835.1097
ENSG00000168517homo_sapiensENSP0000046620051.04938.8112carassius_auratusENSCARP0000010277233.640625.576
ENSG00000168517homo_sapiensENSP000004662005037.7622astyanax_mexicanusENSAMXP0000002803036.202527.3418
ENSG00000168517homo_sapiensENSP0000046620050.699338.8112ictalurus_punctatusENSIPUP0000000621642.151232.2674
ENSG00000168517homo_sapiensENSP0000046620050.699338.4615electrophorus_electricusENSEEEP0000003193741.786731.7003
ENSG00000168517homo_sapiensENSP0000046620052.447638.8112electrophorus_electricusENSEEEP0000002798543.859632.4561
ENSG00000168517homo_sapiensENSP0000046620053.146940.2098oncorhynchus_kisutchENSOKIP0000502038138.287228.9673
ENSG00000168517homo_sapiensENSP0000046620053.146940.2098oncorhynchus_mykissENSOMYP0000007175938.287228.9673
ENSG00000168517homo_sapiensENSP0000046620053.496541.2587oncorhynchus_mykissENSOMYP0000002448940.691531.383
ENSG00000168517homo_sapiensENSP0000046620053.846241.6084salmo_salarENSSSAP0000008523441.066731.7333
ENSG00000168517homo_sapiensENSP0000046620053.496541.2587salmo_salarENSSSAP0000018079640.691531.383
ENSG00000168517homo_sapiensENSP0000046620053.846241.6084salmo_truttaENSSTUP0000000655941.066731.7333
ENSG00000168517homo_sapiensENSP0000046620053.496541.2587salmo_truttaENSSTUP0000005731734.459526.5766
ENSG00000168517homo_sapiensENSP0000046620054.195841.2587gadus_morhuaENSGMOP0000003532041.666731.7204
ENSG00000168517homo_sapiensENSP0000046620051.04938.8112fundulus_heteroclitusENSFHEP0000002771146.056835.0158
ENSG00000168517homo_sapiensENSP0000046620053.846239.1608poecilia_reticulataENSPREP0000001315941.961930.5177
ENSG00000168517homo_sapiensENSP0000046620054.195838.8112xiphophorus_maculatusENSXMAP0000000844142.234330.2452
ENSG00000168517homo_sapiensENSP0000046620054.195839.1608oryzias_latipesENSORLP0000003122842.699730.854
ENSG00000168517homo_sapiensENSP0000046620053.146938.4615cyclopterus_lumpusENSCLMP0000502326242.816930.9859
ENSG00000168517homo_sapiensENSP0000046620055.244839.1608oreochromis_niloticusENSONIP0000002623243.767331.0249
ENSG00000168517homo_sapiensENSP0000046620055.244838.4615haplochromis_burtoniENSHBUP0000002547344.011130.6407
ENSG00000168517homo_sapiensENSP0000046620055.244838.4615astatotilapia_callipteraENSACLP0000000087444.011130.6407
ENSG00000168517homo_sapiensENSP0000046620052.097937.4126sparus_aurataENSSAUP0001003283541.160229.558
ENSG00000168517homo_sapiensENSP0000046620054.895139.1608lates_calcariferENSLCAP0001005095941.755329.7872
ENSG00000168517homo_sapiensENSP0000046620051.748340.9091xenopus_tropicalisENSXETP0000011801550.340139.7959
ENSG00000168517homo_sapiensENSP0000046620032.167825.5245sphenodon_punctatusENSSPUP0000001371542.396333.6406
ENSG00000168517homo_sapiensENSP0000046620055.244838.4615neolamprologus_brichardiENSNBRP0000002682244.011130.6407
ENSG00000168517homo_sapiensENSP0000046620050.699337.4126erpetoichthys_calabaricusENSECRP0000001842842.151231.1047
ENSG00000168517homo_sapiensENSP0000046620047.902137.4126erpetoichthys_calabaricusENSECRP0000001844855.020142.9719
ENSG00000168517homo_sapiensENSP0000046620052.097939.1608kryptolebias_marmoratusENSKMAP0000001469444.082833.1361
ENSG00000168517homo_sapiensENSP0000046620053.496539.1608oryzias_javanicusENSOJAP0000002002143.965532.1839
ENSG00000168517homo_sapiensENSP0000046620055.244839.1608amphilophus_citrinellusENSACIP0000001121044.011131.1978
ENSG00000168517homo_sapiensENSP0000046620053.846238.1119dicentrarchus_labraxENSDLAP0000507802041.066729.0667
ENSG00000168517homo_sapiensENSP0000046620054.195839.5105amphiprion_perculaENSAPEP0000000341642.936331.3019
ENSG00000168517homo_sapiensENSP0000046620053.846238.8112oryzias_sinensisENSOSIP0000000324542.307730.4945
ENSG00000168517homo_sapiensENSP0000046620044.755228.6713seriola_dumeriliENSSDUP0000000909841.558426.6234
ENSG00000168517homo_sapiensENSP0000046620055.244839.5105seriola_dumeriliENSSDUP0000003137043.406631.044
ENSG00000168517homo_sapiensENSP0000046620049.300735.6643cottoperca_gobioENSCGOP0000005047240.63429.3948
ENSG00000168517homo_sapiensENSP0000046620046.503533.2168gasterosteus_aculeatusENSGACP0000001240852.777837.6984
ENSG00000168517homo_sapiensENSP0000046620053.496536.7133cynoglossus_semilaevisENSCSEP0000001575941.689428.6104
ENSG00000168517homo_sapiensENSP0000046620054.195839.5105poecilia_formosaENSPFOP0000002020842.119630.7065
ENSG00000168517homo_sapiensENSP0000046620054.195840.9091myripristis_murdjanENSMMDP0000503274440.897130.8707
ENSG00000168517homo_sapiensENSP000004662005036.3636sander_luciopercaENSSLUP0000002686847.194734.3234
ENSG00000168517homo_sapiensENSP0000046620054.195839.5105amphiprion_ocellarisENSAOCP0000002411242.936331.3019
ENSG00000168517homo_sapiensENSP0000046620053.846241.6084hucho_huchoENSHHUP0000006257140.957431.6489
ENSG00000168517homo_sapiensENSP0000046620054.195840.9091hucho_huchoENSHHUP0000007113439.948530.1546
ENSG00000168517homo_sapiensENSP0000046620054.545539.5105betta_splendensENSBSLP0000003328941.935530.3763
ENSG00000168517homo_sapiensENSP0000046620051.04938.8112pygocentrus_nattereriENSPNAP0000001876644.785334.0491
ENSG00000168517homo_sapiensENSP0000046620053.846237.7622anabas_testudineusENSATEP0000003407741.961929.4278
ENSG00000168517homo_sapiensENSP0000046620025.524518.1818ciona_savignyiENSCSAVP0000000202348.666734.6667
ENSG00000168517homo_sapiensENSP0000046620046.153829.021seriola_lalandi_dorsalisENSSLDP0000003088740.993825.7764
ENSG00000168517homo_sapiensENSP0000046620054.895139.1608seriola_lalandi_dorsalisENSSLDP0000000020243.250730.854
ENSG00000168517homo_sapiensENSP0000046620054.545537.7622labrus_bergyltaENSLBEP0000000862442.857129.6703
ENSG00000168517homo_sapiensENSP0000046620055.244838.8112pundamilia_nyerereiENSPNYP0000001693044.011130.9192
ENSG00000168517homo_sapiensENSP0000046620054.545539.1608mastacembelus_armatusENSMAMP0000003278142.506830.5177
ENSG00000168517homo_sapiensENSP0000046620053.846239.5105stegastes_partitusENSSPAP0000000461642.659331.3019
ENSG00000168517homo_sapiensENSP0000046620053.496540.2098oncorhynchus_tshawytschaENSOTSP0000509804538.059728.607
ENSG00000168517homo_sapiensENSP0000046620053.846241.6084oncorhynchus_tshawytschaENSOTSP0000506790440.957431.6489
ENSG00000168517homo_sapiensENSP0000046620053.846239.5105acanthochromis_polyacanthusENSAPOP0000002372442.541431.2155
ENSG00000168517homo_sapiensENSP0000046620051.04935.6643nothobranchius_furzeriENSNFUP0001500566847.402633.1169
ENSG00000168517homo_sapiensENSP0000046620053.846239.1608cyprinodon_variegatusENSCVAP0000001072942.541430.9392
ENSG00000168517homo_sapiensENSP0000046620046.153837.0629denticeps_clupeoidesENSDCDP0000001532455.230144.3515
ENSG00000168517homo_sapiensENSP0000046620048.601437.7622denticeps_clupeoidesENSDCDP0000001008449.466238.4342
ENSG00000168517homo_sapiensENSP0000046620050.699336.3636larimichthys_croceaENSLCRP0000501892347.077933.7662
ENSG00000168517homo_sapiensENSP0000046620054.545538.4615takifugu_rubripesENSTRUP0000005538142.62330.0546
ENSG00000168517homo_sapiensENSP0000046620049.300736.7133hippocampus_comesENSHCOP0000001932749.823337.1025
ENSG00000168517homo_sapiensENSP0000046620047.202836.7133cyprinus_carpio_carpioENSCCRP0000016814245.608135.473
ENSG00000168517homo_sapiensENSP0000046620051.398639.5105cyprinus_carpio_carpioENSCCRP0000015665342.485532.659
ENSG00000168517homo_sapiensENSP0000046620054.195839.1608poecilia_latipinnaENSPLAP0000000130842.234330.5177
ENSG00000168517homo_sapiensENSP0000046620050.349738.8112sinocyclocheilus_grahamiENSSGRP0000007563744.58234.3653
ENSG00000168517homo_sapiensENSP0000046620050.349738.4615sinocyclocheilus_grahamiENSSGRP0000001932044.720534.1615
ENSG00000168517homo_sapiensENSP0000046620055.244838.4615maylandia_zebraENSMZEP0000503082944.011130.6407
ENSG00000168517homo_sapiensENSP0000046620048.251735.3147tetraodon_nigroviridisENSTNIP0000000013650.181836.7273
ENSG00000168517homo_sapiensENSP0000046620055.244841.2587paramormyrops_kingsleyaeENSPKIP0000000511641.798931.2169
ENSG00000168517homo_sapiensENSP0000046620055.244840.9091paramormyrops_kingsleyaeENSPKIP0000001677344.011132.5905
ENSG00000168517homo_sapiensENSP0000046620054.545541.2587scleropages_formosusENSSFOP0001503928742.62332.2404
ENSG00000168517homo_sapiensENSP0000046620049.650337.4126leptobrachium_leishanenseENSLLEP0000003481748.630136.6438
ENSG00000168517homo_sapiensENSP0000046620052.797236.3636scophthalmus_maximusENSSMAP0000001768740.591427.957
ENSG00000168517homo_sapiensENSP0000046620054.195838.8112oryzias_melastigmaENSOMEP0000001954344.159531.6239

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II2IBA,IDAHomo_sapiens(9606)Process
GO:0004861enables cyclin-dependent protein serine/threonine kinase inhibitor activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1ISSHomo_sapiens(9606)Component
GO:0005654is_active_in nucleoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,ISSHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0017069enables snRNA binding1IDAHomo_sapiens(9606)Function
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0045736involved_in negative regulation of cyclin-dependent protein serine/threonine kinase activity2IBA,IDAHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0097322enables 7SK snRNA binding2IBA,IDAHomo_sapiens(9606)Function

Expression