Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000167553 Gene ID 84790 Accession 20768
Symbol TUBA1C Alias TUBA6;bcm948 Full Name tubulin alpha 1c
Status Confidence Length 46675 bases Strand Plus strand
Position 12 : 49227926 - 49274600 RNA binding domain N.A.
Summary Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in microtubule cytoskeleton and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35513790 The oncogenic role of tubulin alpha-1c chain in human tumours. Xinyao Hu 2022-05-06 BMC cancer

Transcripts

Name Transcript ID bp Protein Translation ID
TUBA1C-205 ENST00000549554 560 No protein -
TUBA1C-207 ENST00000550574 573 No protein -
TUBA1C-202 ENST00000541364 1695 519aa ENSP00000443475
TUBA1C-206 ENST00000549818 536 88aa ENSP00000447669
TUBA1C-209 ENST00000552448 1800 88aa ENSP00000448646
TUBA1C-208 ENST00000552125 575 82aa ENSP00000447910
TUBA1C-204 ENST00000549183 696 130aa ENSP00000448211
TUBA1C-201 ENST00000301072 2823 449aa ENSP00000301072
TUBA1C-203 ENST00000548470 1105 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
29768Lipoprotein(a)6.7670000E-005-
61617Prostatic Neoplasms7E-1221743467
63989Prostatic Neoplasms2E-626034056
91181Prostatic Neoplasms7E-826034056

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000167553homo_sapiensENSP0000035765145.684227.3684homo_sapiensENSP0000030107248.329628.9532
ENSG00000167553homo_sapiensENSP0000032029562.444442.4444homo_sapiensENSP0000030107262.583542.539
ENSG00000167553homo_sapiensENSP0000024843797.991196.4286homo_sapiensENSP0000030107297.772896.2138
ENSG00000167553homo_sapiensENSP0000031869762.556142.8251homo_sapiensENSP0000030107262.138142.539
ENSG00000167553homo_sapiensENSP0000021713360.310440.5765homo_sapiensENSP0000030107260.579140.7572
ENSG00000167553homo_sapiensENSP0000032079738.852121.8543homo_sapiensENSP0000030107239.198222.049
ENSG00000167553homo_sapiensENSP0000025141343.237326.1641homo_sapiensENSP0000030107243.429826.2806
ENSG00000167553homo_sapiensENSP0000033900163.513543.4685homo_sapiensENSP0000030107262.806242.9844
ENSG00000167553homo_sapiensENSP0000036978487.219773.5426homo_sapiensENSP0000030107286.63773.0512
ENSG00000167553homo_sapiensENSP0000033332694.654889.755homo_sapiensENSP0000030107294.654889.755
ENSG00000167553homo_sapiensENSP0000025141243.237325.7206homo_sapiensENSP0000030107243.429825.8352
ENSG00000167553homo_sapiensENSP0000048771979.253172.1992homo_sapiensENSP0000030107242.53938.7528
ENSG00000167553homo_sapiensENSP0000026407163.96443.6937homo_sapiensENSP0000030107263.251743.2071
ENSG00000167553homo_sapiensENSP0000034128963.595543.8202homo_sapiensENSP0000030107263.02943.4298
ENSG00000167553homo_sapiensENSP0000025981863.595543.3708homo_sapiensENSP0000030107263.02942.9844
ENSG00000167553homo_sapiensENSP0000036970363.146142.9213homo_sapiensENSP0000030107262.583542.539
ENSG00000167553homo_sapiensENSP0000045620662.162242.5676homo_sapiensENSP0000030107261.469942.0935
ENSG00000167553homo_sapiensENSP0000049671360.135141.8919homo_sapiensENSP0000030107259.465541.4254
ENSG00000167553homo_sapiensENSP0000033679999.113198.0044homo_sapiensENSP0000030107299.554698.441
ENSG00000167553homo_sapiensENSP0000030107198.891398.0044homo_sapiensENSP0000030107299.331898.441
ENSG00000167553homo_sapiensENSP0000038298298.222296.2222homo_sapiensENSP0000030107298.44196.4365
ENSG00000167553homo_sapiensENSP0000031819797.111194.8889homo_sapiensENSP0000030107297.327495.1002
ENSG00000167553homo_sapiensENSP0000032604298.222296.2222homo_sapiensENSP0000030107298.44196.4365

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000167553homo_sapiensENSP0000030107299.554699.5546pan_paniscusENSPPAP0000002018786.127286.1272
ENSG00000167553homo_sapiensENSP0000030107299.777399.7773pongo_abeliiENSPPYP0000002416486.486586.4865
ENSG00000167553homo_sapiensENSP0000030107299.777399.7773pan_troglodytesENSPTRP0000007187386.319886.3198
ENSG00000167553homo_sapiensENSP0000030107299.777399.7773gorilla_gorillaENSGGOP0000002762386.486586.4865
ENSG00000167553homo_sapiensENSP0000030107299.554698.441notamacropus_eugeniiENSMEUP0000000982799.113198.0044
ENSG00000167553homo_sapiensENSP0000030107299.554698.6637choloepus_hoffmanniENSCHOP0000000526599.554698.6637
ENSG00000167553homo_sapiensENSP0000030107298.44197.9955dasypus_novemcinctusENSDNOP0000002704598.44197.9955
ENSG00000167553homo_sapiensENSP0000030107298.44197.3274erinaceus_europaeusENSEEUP0000000368298.660797.5446
ENSG00000167553homo_sapiensENSP0000030107275.055770.8241echinops_telfairiENSETEP0000001035882.80178.1327
ENSG00000167553homo_sapiensENSP0000030107210099.7773callithrix_jacchusENSCJAP0000007414710099.7773
ENSG00000167553homo_sapiensENSP0000030107297.995597.9955cercocebus_atysENSCATP0000001617391.286391.2863
ENSG00000167553homo_sapiensENSP0000030107299.777399.7773macaca_fascicularisENSMFAP0000002151094.117694.1176
ENSG00000167553homo_sapiensENSP0000030107284.409884.4098macaca_fascicularisENSMFAP0000001082598.955698.9556
ENSG00000167553homo_sapiensENSP00000301072100100macaca_mulattaENSMMUP00000054285100100
ENSG00000167553homo_sapiensENSP0000030107299.777399.5546macaca_nemestrinaENSMNEP0000000042791.615591.411
ENSG00000167553homo_sapiensENSP0000030107297.327496.882papio_anubisENSPANP0000001983897.327496.882
ENSG00000167553homo_sapiensENSP0000030107299.777399.7773mandrillus_leucophaeusENSMLEP0000003912491.615591.6155
ENSG00000167553homo_sapiensENSP0000030107293.763991.314tursiops_truncatusENSTTRP0000000428993.973291.5179
ENSG00000167553homo_sapiensENSP0000030107299.331898.8864equus_asinusENSEASP0000500135691.581191.1704
ENSG00000167553homo_sapiensENSP0000030107299.777398.8864ailuropoda_melanoleucaENSAMEP0000000080610099.1071
ENSG00000167553homo_sapiensENSP0000030107210098.441bos_indicus_hybridENSBIXP0000503771110098.441
ENSG00000167553homo_sapiensENSP0000030107299.777397.7728bos_indicus_hybridENSBIXP0000501586699.777397.7728
ENSG00000167553homo_sapiensENSP0000030107210099.3318oryctolagus_cuniculusENSOCUP0000001865010099.3318
ENSG00000167553homo_sapiensENSP0000030107299.554698.8864marmota_marmota_marmotaENSMMMP0000002632299.776899.1071
ENSG00000167553homo_sapiensENSP0000030107299.554698.2183balaenoptera_musculusENSBMSP0001002421799.554698.2183
ENSG00000167553homo_sapiensENSP0000030107299.777399.3318felis_catusENSFCAP0000001101486.486586.1004
ENSG00000167553homo_sapiensENSP0000030107298.886497.1047bison_bison_bisonENSBBBP0000001680598.886497.1047
ENSG00000167553homo_sapiensENSP0000030107210099.5546jaculus_jaculusENSJJAP0000000604610099.5546
ENSG00000167553homo_sapiensENSP0000030107299.777397.9955ovis_aries_rambouilletENSOARP0002000114999.11597.3451
ENSG00000167553homo_sapiensENSP0000030107299.554698.6637delphinapterus_leucasENSDLEP0000000748199.113198.2262
ENSG00000167553homo_sapiensENSP0000030107299.554697.7728physeter_catodonENSPCTP0000502918599.554697.7728
ENSG00000167553homo_sapiensENSP0000030107268.596967.4833physeter_catodonENSPCTP0000500878097.777896.1905
ENSG00000167553homo_sapiensENSP0000030107210099.3318mus_musculusENSMUSP0000005103310099.3318
ENSG00000167553homo_sapiensENSP0000030107299.331898.8864dipodomys_ordiiENSDORP0000002148399.331898.8864
ENSG00000167553homo_sapiensENSP0000030107245.65745.657mustela_putorius_furoENSMPUP0000001449792.342392.3423
ENSG00000167553homo_sapiensENSP0000030107299.109198.8864aotus_nancymaaeENSANAP0000002713985.741885.5491
ENSG00000167553homo_sapiensENSP0000030107276.169375.5011vicugna_pacosENSVPAP0000000533776.339375.6696
ENSG00000167553homo_sapiensENSP00000301072100100chlorocebus_sabaeusENSCSAP00000002451100100
ENSG00000167553homo_sapiensENSP0000030107210099.1091rattus_norvegicusENSRNOP0000006860310099.1091
ENSG00000167553homo_sapiensENSP0000030107293.763993.7639prolemur_simusENSPSMP00000025680100100
ENSG00000167553homo_sapiensENSP0000030107299.777399.1091microtus_ochrogasterENSMOCP0000001163199.777399.1091
ENSG00000167553homo_sapiensENSP0000030107279.5178.1737sorex_araneusENSSARP0000000790879.157477.827
ENSG00000167553homo_sapiensENSP0000030107210099.3318peromyscus_maniculatus_bairdiiENSPEMP0000001577510099.3318
ENSG00000167553homo_sapiensENSP0000030107254.788453.0067bos_mutusENSBMUP0000003120499.595196.3563
ENSG00000167553homo_sapiensENSP0000030107223.385323.1626bos_mutusENSBMUP0000003119380.769280
ENSG00000167553homo_sapiensENSP0000030107210099.3318mus_spicilegusENSMSIP0000000254110099.3318
ENSG00000167553homo_sapiensENSP0000030107210099.3318cricetulus_griseus_chok1gshdENSCGRP0000100943710099.3318
ENSG00000167553homo_sapiensENSP0000030107293.095891.0913cricetulus_griseus_chok1gshdENSCGRP0000102275296.313494.2396
ENSG00000167553homo_sapiensENSP0000030107296.213893.9866myotis_lucifugusENSMLUP0000001849496.213893.9866
ENSG00000167553homo_sapiensENSP0000030107299.777399.1091neovison_visonENSNVIP0000000838699.777399.1091
ENSG00000167553homo_sapiensENSP0000030107299.777397.7728bos_taurusENSBTAP0000005833299.777397.7728
ENSG00000167553homo_sapiensENSP0000030107299.554697.5501bos_taurusENSBTAP0000006254199.554697.5501
ENSG00000167553homo_sapiensENSP0000030107210098.441bos_taurusENSBTAP0000003818410098.441
ENSG00000167553homo_sapiensENSP0000030107299.554698.6637heterocephalus_glaber_femaleENSHGLP0000004750873.640972.9819
ENSG00000167553homo_sapiensENSP0000030107299.777399.5546sciurus_vulgarisENSSVLP0000501784886.319886.1272
ENSG00000167553homo_sapiensENSP0000030107299.554698.6637nannospalax_galiliENSNGAP0000000515499.113198.2262
ENSG00000167553homo_sapiensENSP0000030107299.109198.2183nannospalax_galiliENSNGAP0000001089598.669697.7827
ENSG00000167553homo_sapiensENSP0000030107299.777398.2183bos_grunniensENSBGRP0000000249310098.4375
ENSG00000167553homo_sapiensENSP0000030107296.88296.2138catagonus_wagneriENSCWAP0000002496888.594787.9837
ENSG00000167553homo_sapiensENSP0000030107260.801860.5791cebus_imitatorENSCCAP000000283496059.7802
ENSG00000167553homo_sapiensENSP0000030107299.109198.441urocitellus_parryiiENSUPAP0001001186699.109198.441
ENSG00000167553homo_sapiensENSP0000030107266.815166.5924moschus_moschiferusENSMMSP0000001599766.518866.2971
ENSG00000167553homo_sapiensENSP0000030107299.777399.5546rhinopithecus_roxellanaENSRROP0000003669591.615591.411
ENSG00000167553homo_sapiensENSP0000030107261.024561.0245mus_pahariMGP_PahariEiJ_P004308498.561198.5611
ENSG00000167553homo_sapiensENSP0000030107299.109198.8864propithecus_coquereliENSPCOP0000002314985.741885.5491
ENSG00000167553homo_sapiensENSP0000030107252.338548.5523callorhinchus_miliiENSCMIP000000059639487.2
ENSG00000167553homo_sapiensENSP0000030107297.104791.7595callorhinchus_miliiENSCMIP0000000531189.896984.9485
ENSG00000167553homo_sapiensENSP0000030107299.331897.5501latimeria_chalumnaeENSLACP0000002159096.328394.6004
ENSG00000167553homo_sapiensENSP0000030107299.554699.1091lepisosteus_oculatusENSLOCP0000000497099.554699.1091
ENSG00000167553homo_sapiensENSP0000030107299.109197.5501esox_luciusENSELUP0000005130591.563890.1235
ENSG00000167553homo_sapiensENSP0000030107299.109196.882oncorhynchus_kisutchENSOKIP0000503227693.684291.5789
ENSG00000167553homo_sapiensENSP0000030107299.331897.3274oncorhynchus_mykissENSOMYP0000006381098.891396.8958
ENSG00000167553homo_sapiensENSP0000030107299.109197.3274salmo_salarENSSSAP0000014575789.357487.751
ENSG00000167553homo_sapiensENSP0000030107299.331897.5501salmo_truttaENSSTUP0000000967798.891397.1175
ENSG00000167553homo_sapiensENSP0000030107299.109197.9955fundulus_heteroclitusENSFHEP0000000634696.320395.2381
ENSG00000167553homo_sapiensENSP0000030107299.109197.7728fundulus_heteroclitusENSFHEP0000001091898.669697.3392
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183poecilia_reticulataENSPREP0000003288897.167896.0784
ENSG00000167553homo_sapiensENSP0000030107297.104793.3185cyclopterus_lumpusENSCLMP0000504199097.977594.1573
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183haplochromis_burtoniENSHBUP0000000527198.891397.7827
ENSG00000167553homo_sapiensENSP0000030107299.109197.9955sparus_aurataENSSAUP0001000100696.320395.2381
ENSG00000167553homo_sapiensENSP0000030107299.331897.9955lates_calcariferENSLCAP0001003599286.266985.1064
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183lates_calcariferENSLCAP0001005235593.110692.0668
ENSG00000167553homo_sapiensENSP0000030107299.554698.441pseudonaja_textilisENSPTXP0000000930599.113198.0044
ENSG00000167553homo_sapiensENSP0000030107279.287378.6192anolis_carolinensisENSACAP0000003744397.267896.4481
ENSG00000167553homo_sapiensENSP0000030107299.109197.9955neolamprologus_brichardiENSNBRP0000000514198.669697.561
ENSG00000167553homo_sapiensENSP0000030107297.995596.4365neolamprologus_brichardiENSNBRP0000000073097.777896.2222
ENSG00000167553homo_sapiensENSP0000030107299.554698.441naja_najaENSNNAP0000000300199.113198.0044
ENSG00000167553homo_sapiensENSP0000030107299.554698.441podarcis_muralisENSPMRP0000000240699.113198.0044
ENSG00000167553homo_sapiensENSP0000030107296.436595.7684geospiza_fortisENSGFOP0000001085398.633397.9499
ENSG00000167553homo_sapiensENSP0000030107299.777399.3318erpetoichthys_calabaricusENSECRP0000002013999.777399.3318
ENSG00000167553homo_sapiensENSP0000030107299.331897.9955kryptolebias_marmoratusENSKMAP0000000862298.891397.561
ENSG00000167553homo_sapiensENSP0000030107298.663796.2138kryptolebias_marmoratusENSKMAP0000002655993.657591.3319
ENSG00000167553homo_sapiensENSP0000030107299.554698.441salvator_merianaeENSSMRP0000000674799.113198.0044
ENSG00000167553homo_sapiensENSP0000030107299.331897.9955oryzias_javanicusENSOJAP0000002253098.672697.3451
ENSG00000167553homo_sapiensENSP0000030107296.659295.3229amphilophus_citrinellusENSACIP0000001920198.412797.0522
ENSG00000167553homo_sapiensENSP0000030107299.109197.9955dicentrarchus_labraxENSDLAP0000500979197.161696.0699
ENSG00000167553homo_sapiensENSP0000030107290.423287.7506amphiprion_perculaENSAPEP0000002588097.596294.7115
ENSG00000167553homo_sapiensENSP0000030107297.550194.6548amphiprion_perculaENSAPEP0000002883194.805291.9913
ENSG00000167553homo_sapiensENSP0000030107297.772895.1002amphiprion_perculaENSAPEP0000002792895.021692.4242
ENSG00000167553homo_sapiensENSP0000030107251.447750.5568gopherus_evgoodeiENSGEVP0000501123497.468495.7806
ENSG00000167553homo_sapiensENSP0000030107299.331898.441chelonoidis_abingdoniiENSCABP0000000961092.531191.7012
ENSG00000167553homo_sapiensENSP0000030107299.554698.8864chelonoidis_abingdoniiENSCABP0000000958589.221688.6228
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183seriola_dumeriliENSSDUP0000000510498.891397.7827
ENSG00000167553homo_sapiensENSP0000030107297.995595.1002cottoperca_gobioENSCGOP0000002280491.666788.9583
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183poecilia_formosaENSPFOP0000000796898.891397.7827
ENSG00000167553homo_sapiensENSP0000030107298.218396.4365myripristis_murdjanENSMMDP0000501481393.829892.1277
ENSG00000167553homo_sapiensENSP0000030107298.663797.1047myripristis_murdjanENSMMDP0000500762894.255392.766
ENSG00000167553homo_sapiensENSP0000030107298.886497.3274myripristis_murdjanENSMMDP0000500764594.871893.3761
ENSG00000167553homo_sapiensENSP0000030107297.995595.3229amphiprion_ocellarisENSAOCP0000000691397.56194.9002
ENSG00000167553homo_sapiensENSP0000030107297.995595.3229amphiprion_ocellarisENSAOCP0000000566397.56194.9002
ENSG00000167553homo_sapiensENSP0000030107298.886496.882hucho_huchoENSHHUP0000003632893.081891.195
ENSG00000167553homo_sapiensENSP0000030107298.663796.4365betta_splendensENSBSLP0000001821998.226296.0089
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183betta_splendensENSBSLP0000001933977.565276.6957
ENSG00000167553homo_sapiensENSP0000030107299.554698.8864pygocentrus_nattereriENSPNAP0000000225299.554698.8864
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183anabas_testudineusENSATEP0000003531898.891397.7827
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183seriola_lalandi_dorsalisENSSLDP0000002172198.891397.7827
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183mastacembelus_armatusENSMAMP0000000613296.746295.6616
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183stegastes_partitusENSSPAP0000002464898.891397.7827
ENSG00000167553homo_sapiensENSP0000030107299.109197.3274oncorhynchus_tshawytschaENSOTSP0000509129498.669696.8958
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183acanthochromis_polyacanthusENSAPOP0000003361089.738488.7324
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183cyprinodon_variegatusENSCVAP0000000620198.891397.7827
ENSG00000167553homo_sapiensENSP0000030107296.213892.8731larimichthys_croceaENSLCRP0000502150095.154291.8502
ENSG00000167553homo_sapiensENSP0000030107299.554698.441ficedula_albicollisENSFALP0000002915989.221688.2236
ENSG00000167553homo_sapiensENSP0000030107298.663797.3274hippocampus_comesENSHCOP0000000789598.444497.1111
ENSG00000167553homo_sapiensENSP0000030107298.886497.7728hippocampus_comesENSHCOP0000001319387.058886.0784
ENSG00000167553homo_sapiensENSP0000030107291.536890.2004poecilia_latipinnaENSPLAP0000001350798.798197.3558
ENSG00000167553homo_sapiensENSP0000030107299.331898.2183maylandia_zebraENSMZEP0000502990098.891397.7827
ENSG00000167553homo_sapiensENSP0000030107291.091389.5323tetraodon_nigroviridisENSTNIP0000001539897.38195.7143
ENSG00000167553homo_sapiensENSP0000030107299.331898.441paramormyrops_kingsleyaeENSPKIP0000001978198.891398.0044
ENSG00000167553homo_sapiensENSP0000030107299.554698.8864scleropages_formosusENSSFOP0001504262199.333398.6667

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000226involved_in microtubule cytoskeleton organization1IBAHomo_sapiens(9606)Process
GO:0000278involved_in mitotic cell cycle1IBAHomo_sapiens(9606)Process
GO:0005198enables structural molecule activity1TASHomo_sapiens(9606)Function
GO:0005200enables structural constituent of cytoskeleton1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005525enables GTP binding1IBAHomo_sapiens(9606)Function
GO:0005634located_in nucleus2HDA,IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005874is_active_in microtubule2IBA,TASHomo_sapiens(9606)Component
GO:0005881located_in cytoplasmic microtubule1IEAHomo_sapiens(9606)Component
GO:0007017involved_in microtubule-based process1TASHomo_sapiens(9606)Process
GO:0015630located_in microtubule cytoskeleton1IDAHomo_sapiens(9606)Component
GO:0016787enables hydrolase activity1IEAHomo_sapiens(9606)Function
GO:0030705involved_in cytoskeleton-dependent intracellular transport1TASHomo_sapiens(9606)Process
GO:0031982located_in vesicle1HDAHomo_sapiens(9606)Component
GO:0045121located_in membrane raft1IEAHomo_sapiens(9606)Component
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0051301involved_in cell division1TASHomo_sapiens(9606)Process

Expression