Drugs target to TUBA1C

Drug name Drug type Disease/phenotype Mechanism of action(MoA) Phase Status Source
PACLITAXEL POLIGLUMEXSmall moleculenoneTubulin stabiliser3['Active, not recruiting', 'Withdrawn', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Active, not recruiting', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Terminated', 'Active, not recruiting', 'Completed', 'Terminated', 'Active, not recruiting', '-', 'Active, not recruiting', 'Active, not recruiting', 'Active, not recruiting', 'Active, not recruiting', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
PLINABULINSmall moleculenoneTubulin inhibitor3['Active, not recruiting', 'Recruiting', 'Terminated', 'Not yet recruiting', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Active, not recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
VINFLUNINESmall moleculenoneTubulin inhibitor4['Completed', 'Withdrawn', 'Withdrawn', 'Withdrawn', 'Terminated', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Completed', '-', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ATC', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
LORVOTUZUMAB MERTANSINEAntibodynoneTubulin inhibitor2['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
ARX-788UnknownnoneTubulin inhibitor2['Recruiting', 'Terminated', 'Recruiting', 'Recruiting', 'Active, not recruiting', 'Withdrawn', 'Recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
DOLASTATIN-10Small moleculenoneTubulin inhibitor2['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
SAGOPILONESmall moleculenoneTubulin stabiliser2['Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
MIRVETUXIMAB SORAVTANSINEAntibodynoneTubulin inhibitor2['Completed', 'Withdrawn', 'Withdrawn', 'Completed', 'Completed', 'Recruiting', 'Withdrawn', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
FOSBRETABULINSmall moleculenoneTubulin inhibitor3['Terminated', 'Completed', 'Completed', 'Withdrawn', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
INDIBULINSmall moleculenoneTubulin inhibitor1['Unknown status', 'Completed', 'Completed', 'Unknown status']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
OMBRABULINSmall moleculenoneTubulin inhibitor3['Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
CROLIBULINSmall moleculenoneTubulin inhibitor1['Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials']
MILATAXELSmall moleculenoneTubulin inhibitor2['Completed', 'Completed', 'Completed', 'Unknown status']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
FOSBRETABULIN DISODIUMSmall moleculenoneTubulin inhibitor2['Completed', 'Completed', 'Completed', 'Terminated', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TUSAMITAMAB RAVTANSINEAntibodynoneTubulin inhibitor3['Recruiting', 'Recruiting', 'Recruiting', 'Active, not recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
LEXIBULINSmall moleculenoneTubulin inhibitor2['Terminated', 'Terminated']['ClinicalTrials', 'ClinicalTrials']
ANG1005ProteinnoneTubulin inhibitor2['Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
T-900607Small moleculenoneTubulin disrupting agent2['Completed', 'Unknown status', 'Terminated', 'Completed', 'Unknown status']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
SOBLIDOTINSmall moleculenoneTubulin inhibitor2['Completed', 'Completed', 'Withdrawn']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
FOSBRETABULIN TROMETHAMINESmall moleculenoneTubulin disrupting agent2['Completed', 'Terminated']['ClinicalTrials', 'ClinicalTrials']
VERUBULINSmall moleculenoneTubulin disrupting agent2['Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
DAVUNETIDEProteinnoneTubulin stabiliser2['Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
PLOCABULINSmall moleculenoneTubulin inhibitor2['Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials']
PRALUZATAMAB RAVTANSINEAntibodynoneTubulin inhibitor2['Active, not recruiting']['ClinicalTrials']