Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs diverse
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000165799 Gene ID 84659 Accession 19278
Symbol RNASE7 Alias RAE1 Full Name ribonuclease A family member 7
Status Confidence Length 1919 bases Strand Plus strand
Position 14 : 21042316 - 21044234 RNA binding domain RnaseA
Summary The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000298690 RnaseA PF00074 3e-39 1
ENSP00000431382 RnaseA PF00074 3e-39 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RNASE7-202 ENST00000481538 922 156aa ENSP00000431382
RNASE7-201 ENST00000298690 1362 156aa ENSP00000298690

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
43048Platelet Function Tests2.4881671E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000165799homo_sapiensENSP0000031139885.714377.9221homo_sapiensENSP0000029869084.615476.9231
ENSG00000165799homo_sapiensENSP0000051286731.292519.7279homo_sapiensENSP0000029869029.487218.5897
ENSG00000165799homo_sapiensENSP0000030204665.333354homo_sapiensENSP0000029869062.820551.9231
ENSG00000165799homo_sapiensENSP0000039299629.166719.9074homo_sapiensENSP0000029869040.384627.5641
ENSG00000165799homo_sapiensENSP0000045131826.633215.0754homo_sapiensENSP0000029869033.974419.2308
ENSG00000165799homo_sapiensENSP0000038107742.176930.6122homo_sapiensENSP0000029869039.743628.8462
ENSG00000165799homo_sapiensENSP0000038468326.666715.2381homo_sapiensENSP0000029869035.897420.5128
ENSG00000165799homo_sapiensENSP0000038105751.923134.6154homo_sapiensENSP0000029869051.923134.6154
ENSG00000165799homo_sapiensENSP0000045224546.938836.0544homo_sapiensENSP0000029869044.230833.9744
ENSG00000165799homo_sapiensENSP0000037241035.897421.7949homo_sapiensENSP0000029869035.897421.7949
ENSG00000165799homo_sapiensENSP0000030232452.538.125homo_sapiensENSP0000029869053.846239.1026
ENSG00000165799homo_sapiensENSP0000030327654.037339.1304homo_sapiensENSP0000029869055.769240.3846

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000165799homo_sapiensENSP0000029869099.35998.0769pan_paniscusENSPPAP0000002018599.35998.0769
ENSG00000165799homo_sapiensENSP0000029869098.076994.2308pongo_abeliiENSPPYP0000000635598.076994.2308
ENSG00000165799homo_sapiensENSP0000029869099.35998.0769pan_troglodytesENSPTRP0000006502399.35998.0769
ENSG00000165799homo_sapiensENSP0000029869099.35998.0769gorilla_gorillaENSGGOP0000003913099.35998.0769
ENSG00000165799homo_sapiensENSP0000029869095.512892.3077macaca_fascicularisENSMFAP0000005895795.512892.3077
ENSG00000165799homo_sapiensENSP0000029869095.512892.3077macaca_mulattaENSMMUP0000006111995.512892.3077
ENSG00000165799homo_sapiensENSP0000029869095.512891.6667papio_anubisENSPANP0000005272095.512891.6667
ENSG00000165799homo_sapiensENSP0000029869078.846265.3846ailuropoda_melanoleucaENSAMEP0000002110878.846265.3846
ENSG00000165799homo_sapiensENSP0000029869083.333371.7949bos_indicus_hybridENSBIXP0000501634083.333371.7949
ENSG00000165799homo_sapiensENSP0000029869075.64164.1026oryctolagus_cuniculusENSOCUP0000000056675.64164.1026
ENSG00000165799homo_sapiensENSP0000029869083.333369.8718marmota_marmota_marmotaENSMMMP0000001677379.754666.8712
ENSG00000165799homo_sapiensENSP0000029869082.692367.9487balaenoptera_musculusENSBMSP0001001259282.692367.9487
ENSG00000165799homo_sapiensENSP0000029869069.871855.7692felis_catusENSFCAP0000003651269.871855.7692
ENSG00000165799homo_sapiensENSP0000029869058.974447.4359ursus_americanusENSUAMP0000001381056.097645.122
ENSG00000165799homo_sapiensENSP0000029869083.974471.7949bison_bison_bisonENSBBBP0000000185883.974471.7949
ENSG00000165799homo_sapiensENSP0000029869082.692369.2308monodon_monocerosENSMMNP0001501310382.692369.2308
ENSG00000165799homo_sapiensENSP0000029869083.974472.4359sus_scrofaENSSSCP0000002368783.974472.4359
ENSG00000165799homo_sapiensENSP0000029869082.051369.8718ovis_aries_rambouilletENSOARP0002001945182.051369.8718
ENSG00000165799homo_sapiensENSP0000029869067.948753.2051delphinapterus_leucasENSDLEP0000000249137.455829.3286
ENSG00000165799homo_sapiensENSP0000029869070.512856.4103vicugna_pacosENSVPAP0000000483771.895457.5163
ENSG00000165799homo_sapiensENSP0000029869081.410373.0769tupaia_belangeriENSTBEP0000000444581.935573.5484
ENSG00000165799homo_sapiensENSP0000029869080.128270.5128camelus_dromedariusENSCDRP0000500318980.128270.5128
ENSG00000165799homo_sapiensENSP0000029869073.717962.1795carlito_syrichtaENSTSYP0000000889482.733869.7842
ENSG00000165799homo_sapiensENSP0000029869085.897477.5641prolemur_simusENSPSMP0000001736885.350377.0701
ENSG00000165799homo_sapiensENSP0000029869083.333371.7949bos_mutusENSBMUP0000002545283.333371.7949
ENSG00000165799homo_sapiensENSP0000029869083.974472.4359rhinolophus_ferrumequinumENSRFEP0001002696583.974472.4359
ENSG00000165799homo_sapiensENSP0000029869050.64146.1538sciurus_vulgarisENSSVLP0000500169177.45170.5882
ENSG00000165799homo_sapiensENSP0000029869079.487271.1538sciurus_vulgarisENSSVLP000050017028071.6129
ENSG00000165799homo_sapiensENSP0000029869083.333371.1538cervus_hanglu_yarkandensisENSCHYP0000002009183.333371.1538
ENSG00000165799homo_sapiensENSP0000029869083.333371.1538catagonus_wagneriENSCWAP0000000824083.333371.1538
ENSG00000165799homo_sapiensENSP0000029869084.615474.359ictidomys_tridecemlineatusENSSTOP0000001932084.615474.359
ENSG00000165799homo_sapiensENSP0000029869087.820580.1282otolemur_garnettiiENSOGAP0000000102486.708979.1139
ENSG00000165799homo_sapiensENSP0000029869073.076966.0256urocitellus_parryiiENSUPAP0001000238169.090962.4242
ENSG00000165799homo_sapiensENSP0000029869080.769270.5128urocitellus_parryiiENSUPAP0001000259082.352971.8954
ENSG00000165799homo_sapiensENSP0000029869081.410369.8718moschus_moschiferusENSMMSP0000001091181.410369.8718

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001530enables lipopolysaccharide binding1IDAHomo_sapiens(9606)Function
GO:0003676enables nucleic acid binding1IEAHomo_sapiens(9606)Function
GO:0004519enables endonuclease activity1IEAHomo_sapiens(9606)Function
GO:0004540enables RNA nuclease activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005576located_in extracellular region3IDA,NAS,TASHomo_sapiens(9606)Component
GO:0005615is_active_in extracellular space2IBA,IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0019731involved_in antibacterial humoral response1IDAHomo_sapiens(9606)Process
GO:0042834enables peptidoglycan binding1IDAHomo_sapiens(9606)Function
GO:0045087involved_in innate immune response3IBA,IDA,NASHomo_sapiens(9606)Process
GO:0050829involved_in defense response to Gram-negative bacterium2IBA,IDAHomo_sapiens(9606)Process
GO:0050830involved_in defense response to Gram-positive bacterium2IBA,IDAHomo_sapiens(9606)Process
GO:0050832involved_in defense response to fungus2IBA,IDAHomo_sapiens(9606)Process
GO:0051715involved_in cytolysis in another organism1IDAHomo_sapiens(9606)Process
GO:0061844involved_in antimicrobial humoral immune response mediated by antimicrobial peptide1IDAHomo_sapiens(9606)Process

Expression