Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000163877 Gene ID 79753 Accession 30587
Symbol SNIP1 Alias PML1;PMRED;NEDHCS Full Name Smad nuclear interacting protein 1
Status Confidence Length 19845 bases Strand Minus strand
Position 1 : 37534449 - 37554293 RNA binding domain N.A.
Summary This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED). [provided by RefSeq, Mar 2012]

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression