Ensembl ID ENSG00000163877 Gene ID 79753 Accession 30587
Gene Symbol SNIP1 Alias PML1;PMRED;NEDHCS Full Name Smad nuclear interacting protein 1
Position 1 : 37534449 - 37554293 Length 19845 bases Strand Minus strand
Status Confidence Main interacting RNAsncRNARBP type Non-canonical_RBPs
Summary This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED). [provided by RefSeq, Mar 2012]

ENSG00000163877 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000163877 SNIP1 -0.5 2.68e-13 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000163877 SNIP1 non-small cell lung cancer 17157259
ENSG00000163877 SNIP1 tumors 17189184
ENSG00000163877 SNIP1 tumour 17260016
ENSG00000163877 SNIP1 cancer 18794151
ENSG00000163877 SNIP1 cancer 23897559
ENSG00000163877 SNIP1 non-small cell lung cancer 23932364
ENSG00000163877 SNIP1 tumors 29634978
ENSG00000163877 SNIP1 breast cancer 30404004
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000163877 SNIP1 MESO 0.017 low
ENSG00000163877 SNIP1 SARC 0.0046 high
ENSG00000163877 SNIP1 STAD 0.0042 low
ENSG00000163877 SNIP1 HNSC 0.0078 low
ENSG00000163877 SNIP1 READ 0.026 low
ENSG00000163877 SNIP1 KIRP 0.04 low
ENSG00000163877 SNIP1 LUAD 0.0012 low
ENSG00000163877 SNIP1 PCPG 0.0047 low
ENSG00000163877 SNIP1 THYM 0.012 low
ENSG00000163877 SNIP1 COAD 0.0013 low
ENSG00000163877 SNIP1 OV 0.036 high
ENSG00000163877 SNIP1 KIRC 0.00019 low
ENSG00000163877 SNIP1 PRAD 0.0013 high
ENSG00000163877 SNIP1 TGCT 0.017 high
ENSG00000163877 SNIP1 LAML 0.049 low
ENSG00000163877 SNIP1 GBM 0.042 high
ENSG00000163877 SNIP1 SKCM 0.027 low
ENSG00000163877 SNIP1 LIHC 0.049 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000163877 SNIP1 CHOL Del 1.312877 0.261640 0.565453 0.305556
ENSG00000163877 SNIP1 KIRP Del 1.272423 0.032705 0.594486 0.142361
ENSG00000163877 SNIP1 LIHC Del 3.872606 0.109143 0.512531 0.305405
ENSG00000163877 SNIP1 PCPG Del 1.385592 0.072845 0.673848 0.623457
ENSG00000163877 SNIP1 KIRC Del 0.928526 0.026451 0.417010 0.153409
ENSG00000163877 SNIP1 UVM Del 1.628635 0.094732 0.809086 0.300000
ENSG00000163877 SNIP1 OV Amp 13.267781 0.599948 0.740751 0.468048