RBP Type
Canonical_RBPs
Diseases
SARS-COV-OC43 Flaviviruses HIV IAV RV SARS-COV-2 SINV Dengue Zika
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
Stress granucle
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000161960 Gene ID
1973 Accession
3282
Symbol
EIF4A1
Alias
DDX2A;EIF4A;EIF-4A;eIF4A-I;eIF-4A-I
Full Name
eukaryotic translation initiation factor 4A1
Status
Confidence
Length
6182 bases
Strand
Plus strand
Position
17 : 7572825 - 7579006
RNA binding domain
ResIII , DEAD
Summary
Enables double-stranded RNA binding activity. Predicted to be involved in cytoplasmic translational initiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000462753
DEAD
PF00270 1e-43
1
ENSP00000462753
ResIII
PF04851 1.8e-06
2
ENSP00000463486
DEAD
PF00270 1.1e-43
1
ENSP00000463486
ResIII
PF04851 1.8e-06
2
ENSP00000293831
DEAD
PF00270 1.4e-43
1
ENSP00000293831
ResIII
PF04851 2.6e-06
2
ENSP00000464550
DEAD
PF00270 7.4e-41
1
ENSP00000464550
ResIII
PF04851 1.2e-05
2
ENSP00000463366
DEAD
PF00270 3.1e-39
1
ENSP00000463366
ResIII
PF04851 2e-05
2
ENSP00000464066
DEAD
PF00270 1.8e-38
1
ENSP00000464066
ResIII
PF04851 2e-05
2
ENSP00000463634
DEAD
PF00270 7.5e-38
1
ENSP00000463634
ResIII
PF04851 2.5e-05
2
ENSP00000462275
DEAD
PF00270 2.4e-34
1
ENSP00000462275
ResIII
PF04851 3.8e-05
2
ENSP00000463309
DEAD
PF00270 4.2e-27
1
ENSP00000463309
ResIII
PF04851 0.00031
2
ENSP00000462719
DEAD
PF00270 4.5e-22
1
ENSP00000463067
DEAD
PF00270 4.9e-09
1
ENSP00000462372
DEAD
PF00270 4.2e-07
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
36727461 eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation.
Tobias Schmidt
2023-02-28
Nucleic acids research
27239032 CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A.
Jennifer Chu
2016-06-14
Cell reports
35602299 A N7 -Methylguanine-Related Gene Signature Applicable for the Prognosis and Microenvironment of Prostate Cancer.
Wangli Mei
2022-01-01
Journal of oncology
36973570 5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
Chengdong Wu
2023-06-01
Frontiers of medicine
34604625 Molecular Dynamics Simulations Identify Tractable Lead-like Phenyl-Piperazine Scaffolds as eIF4A1 ATP-competitive Inhibitors.
J Derek Essegian
2021-09-28
ACS omega
27009120 miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning.
Duygu Kuzuoğlu-Öztürk
2016-06-01
The EMBO journal
32575790 General and Target-Specific DExD/H RNA Helicases in Eukaryotic Translation Initiation.
Leo Shen
2020-06-20
International journal of molecular sciences
32101697 Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F.
Jennifer Chu
2020-02-25
Cell reports
31791371 eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.
Ania Wilczynska
2019-12-02
Genome biology
30718665 Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation.
Rayelle R Itoua
2019-02-04
Scientific reports
32749456 RNA-tethering assay and eIF4G:eIF4A obligate dimer design uncovers multiple eIF4F functional complexes.
Francis Robert
2020-09-04
Nucleic acids research
36151083 Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules.
Tao Wang
2022-09-23
Nature communications
25208567 Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation.
Viktor Todorovic
2014-11-15
Molecular biology of the cell
36552834 eIF4A/PDCD4 Pathway, a Factor for Doxorubicin Chemoresistance in a Triple-Negative Breast Cancer Cell Model.
Alina González-Ortiz
2022-12-15
Cells
33296667 Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A.
Mingming Chen
2021-04-15
Cell chemical biology
33412110 Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.
Kiran Sai Naineni
2021-06-17
Cell chemical biology
32766783 Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions.
Jutta Steinberger
2020-09-25
Nucleic acids research
37291191 Broad anti-pathogen potential of DEAD box RNA helicase eIF4A-targeting rocaglates.
Wiebke Obermann
2023-06-08
Scientific reports
35361883 Epigenetic regulation of EIF4A1 through DNA methylation and an oncogenic role of eIF4A1 through BRD2 signaling in prostate cancer.
Chao Wang
2022-05-01
Oncogene
Name
Transcript ID
bp
Protein
Translation ID
EIF4A1-230
ENST00000584054
716
No protein
-
EIF4A1-201
ENST00000293831
1758
406aa
ENSP00000293831
EIF4A1-215
ENST00000580886
562
No protein
-
EIF4A1-214
ENST00000580461
909
74aa
ENSP00000464320
EIF4A1-231
ENST00000584712
782
No protein
-
EIF4A1-208
ENST00000578476
573
74aa
ENSP00000464082
EIF4A1-222
ENST00000582169
552
134aa
ENSP00000463309
EIF4A1-211
ENST00000578754
547
117aa
ENSP00000463067
EIF4A1-209
ENST00000578495
916
300aa
ENSP00000464550
EIF4A1-202
ENST00000396527
1169
No protein
-
EIF4A1-213
ENST00000579139
568
85aa
ENSP00000461921
EIF4A1-212
ENST00000579085
569
No protein
-
EIF4A1-223
ENST00000582213
560
No protein
-
EIF4A1-229
ENST00000583899
665
No protein
-
EIF4A1-225
ENST00000582848
591
No protein
-
EIF4A1-236
ENST00000585024
577
187aa
ENSP00000462275
EIF4A1-228
ENST00000583802
563
163aa
ENSP00000463634
EIF4A1-235
ENST00000584901
1021
No protein
-
EIF4A1-217
ENST00000581544
1444
95aa
ENSP00000463821
EIF4A1-203
ENST00000577269
1319
347aa
ENSP00000463486
EIF4A1-232
ENST00000584784
818
271aa
ENSP00000463366
EIF4A1-224
ENST00000582746
1645
341aa
ENSP00000462753
EIF4A1-234
ENST00000584860
1109
No protein
-
EIF4A1-218
ENST00000581770
447
No protein
-
EIF4A1-205
ENST00000577738
531
No protein
-
EIF4A1-216
ENST00000581384
642
187aa
ENSP00000464066
EIF4A1-206
ENST00000577929
696
85aa
ENSP00000462372
EIF4A1-207
ENST00000578324
1577
No protein
-
EIF4A1-233
ENST00000584798
1440
No protein
-
EIF4A1-204
ENST00000577731
574
No protein
-
EIF4A1-227
ENST00000583389
951
230aa
ENSP00000462719
EIF4A1-210
ENST00000578569
583
No protein
-
EIF4A1-226
ENST00000583217
599
No protein
-
EIF4A1-220
ENST00000581841
621
No protein
-
EIF4A1-221
ENST00000582050
576
68aa
ENSP00000463380
EIF4A1-219
ENST00000581808
205
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000161960 homo_sapiens ENSP00000379475 51.1682 33.4112 homo_sapiens ENSP00000293831 53.9409 35.2217 ENSG00000161960 homo_sapiens ENSP00000385536 27.1605 19.0672 homo_sapiens ENSP00000293831 48.7685 34.2365 ENSG00000161960 homo_sapiens ENSP00000263239 28.9552 17.0149 homo_sapiens ENSP00000293831 47.7833 28.0788 ENSG00000161960 homo_sapiens ENSP00000497641 80.292 65.6934 homo_sapiens ENSP00000293831 81.2808 66.5025 ENSG00000161960 homo_sapiens ENSP00000482680 26.9281 15.4248 homo_sapiens ENSP00000293831 50.7389 29.064 ENSG00000161960 homo_sapiens ENSP00000306117 52.5105 34.3096 homo_sapiens ENSP00000293831 61.8227 40.3941 ENSG00000161960 homo_sapiens ENSP00000288071 52.4008 34.8643 homo_sapiens ENSP00000293831 61.8227 41.133 ENSG00000161960 homo_sapiens ENSP00000481495 23.5157 12.6892 homo_sapiens ENSP00000293831 49.7537 26.8473 ENSG00000161960 homo_sapiens ENSP00000416534 19.9612 12.3062 homo_sapiens ENSP00000293831 50.7389 31.2808 ENSG00000161960 homo_sapiens ENSP00000361232 26.1394 15.2815 homo_sapiens ENSP00000293831 48.0296 28.0788 ENSG00000161960 homo_sapiens ENSP00000492643 13.2331 7.5188 homo_sapiens ENSP00000293831 43.3498 24.6305 ENSG00000161960 homo_sapiens ENSP00000238146 31 18.5 homo_sapiens ENSP00000293831 45.8128 27.3399 ENSG00000161960 homo_sapiens ENSP00000225792 33.0619 22.1498 homo_sapiens ENSP00000293831 50 33.4975 ENSG00000161960 homo_sapiens ENSP00000368667 31.3788 18.7005 homo_sapiens ENSP00000293831 48.7685 29.064 ENSG00000161960 homo_sapiens ENSP00000330460 33.441 18.2553 homo_sapiens ENSP00000293831 50.9852 27.8325 ENSG00000161960 homo_sapiens ENSP00000263576 50.5176 32.7122 homo_sapiens ENSP00000293831 60.0985 38.9163 ENSG00000161960 homo_sapiens ENSP00000380495 27.6276 16.2162 homo_sapiens ENSP00000293831 45.3202 26.601 ENSG00000161960 homo_sapiens ENSP00000314348 21.4857 12.1143 homo_sapiens ENSP00000293831 46.3054 26.1084 ENSG00000161960 homo_sapiens ENSP00000346120 25.9259 16.2197 homo_sapiens ENSP00000293831 50 31.2808 ENSG00000161960 homo_sapiens ENSP00000374574 20.0426 12.2601 homo_sapiens ENSP00000293831 46.3054 28.3251 ENSG00000161960 homo_sapiens ENSP00000358716 25 15.8981 homo_sapiens ENSP00000293831 50.7389 32.266 ENSG00000161960 homo_sapiens ENSP00000442266 43.8923 26.294 homo_sapiens ENSP00000293831 52.2167 31.2808 ENSG00000161960 homo_sapiens ENSP00000362687 27.8155 17.232 homo_sapiens ENSP00000293831 50.4926 31.2808 ENSG00000161960 homo_sapiens ENSP00000479504 32.8881 19.8664 homo_sapiens ENSP00000293831 48.5222 29.3103 ENSG00000161960 homo_sapiens ENSP00000359361 32.5617 20.3704 homo_sapiens ENSP00000293831 51.9704 32.5123 ENSG00000161960 homo_sapiens ENSP00000326381 96.0688 89.6806 homo_sapiens ENSP00000293831 96.3054 89.9015 ENSG00000161960 homo_sapiens ENSP00000258772 35.649 20.4753 homo_sapiens ENSP00000293831 48.0296 27.5862 ENSG00000161960 homo_sapiens ENSP00000494040 32.1752 20.0906 homo_sapiens ENSP00000293831 52.4631 32.7586 ENSG00000161960 homo_sapiens ENSP00000336725 32.5758 19.3939 homo_sapiens ENSP00000293831 52.9557 31.5271 ENSG00000161960 homo_sapiens ENSP00000247003 38.5093 24.6377 homo_sapiens ENSP00000293831 45.8128 29.3103 ENSG00000161960 homo_sapiens ENSP00000330349 30.3859 18.328 homo_sapiens ENSP00000293831 46.5517 28.0788 ENSG00000161960 homo_sapiens ENSP00000242776 51.5222 33.0211 homo_sapiens ENSP00000293831 54.1872 34.7291 ENSG00000161960 homo_sapiens ENSP00000233084 29.0541 17.7027 homo_sapiens ENSP00000293831 52.9557 32.266 ENSG00000161960 homo_sapiens ENSP00000304072 23.042 13.7344 homo_sapiens ENSP00000293831 50 29.803 ENSG00000161960 homo_sapiens ENSP00000350698 42.8571 25.9341 homo_sapiens ENSP00000293831 48.0296 29.064 ENSG00000161960 homo_sapiens ENSP00000310723 24.3902 14.6341 homo_sapiens ENSP00000293831 49.2611 29.5567 ENSG00000161960 homo_sapiens ENSP00000332340 32.963 19.8148 homo_sapiens ENSP00000293831 43.8424 26.3547 ENSG00000161960 homo_sapiens ENSP00000424838 28.1768 16.5746 homo_sapiens ENSP00000293831 50.2463 29.5567
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000161960 homo_sapiens ENSP00000293831 99.5074 99.2611 nomascus_leucogenys ENSNLEP00000011715 99.0196 98.7745 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 pan_paniscus ENSPPAP00000034134 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 99.2611 99.0148 pongo_abelii ENSPPYP00000030648 99.0172 98.7715 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 pan_troglodytes ENSPTRP00000014825 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 gorilla_gorilla ENSGGOP00000027144 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 98.5222 97.2906 ornithorhynchus_anatinus ENSOANP00000033527 55.4785 54.785 ENSG00000161960 homo_sapiens ENSP00000293831 99.5074 98.7685 sarcophilus_harrisii ENSSHAP00000037048 93.7355 93.0394 ENSG00000161960 homo_sapiens ENSP00000293831 87.931 87.1921 notamacropus_eugenii ENSMEUP00000009834 99.7207 98.8827 ENSG00000161960 homo_sapiens ENSP00000293831 99.5074 99.5074 dasypus_novemcinctus ENSDNOP00000018959 99.7531 99.7531 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 erinaceus_europaeus ENSEEUP00000003259 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 callithrix_jacchus ENSCJAP00000027897 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 cercocebus_atys ENSCATP00000038402 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 99.7537 98.7685 macaca_fascicularis ENSMFAP00000017832 99.7537 98.7685 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 macaca_mulatta ENSMMUP00000017746 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 papio_anubis ENSPANP00000019635 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 mandrillus_leucophaeus ENSMLEP00000017086 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 tursiops_truncatus ENSTTRP00000009680 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 98.7685 98.7685 equus_asinus ENSEASP00005047550 98.2843 98.2843 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 capra_hircus ENSCHIP00000025335 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 99.7537 loxodonta_africana ENSLAFP00000000931 100 99.7537 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 panthera_leo ENSPLOP00000028740 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 ailuropoda_melanoleuca ENSAMEP00000026132 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 bos_indicus_hybrid ENSBIXP00005040005 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 oryctolagus_cuniculus ENSOCUP00000008940 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 98.7685 98.7685 equus_caballus ENSECAP00000019298 98.2843 98.2843 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 canis_lupus_familiaris ENSCAFP00845032483 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 panthera_pardus ENSPPRP00000013767 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 marmota_marmota_marmota ENSMMMP00000022407 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 98.5222 98.2759 cavia_porcellus ENSCPOP00000004412 100 99.75 ENSG00000161960 homo_sapiens ENSP00000293831 98.7685 98.2759 felis_catus ENSFCAP00000052569 74.122 73.7523 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 ursus_americanus ENSUAMP00000003884 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 48.5222 46.798 monodelphis_domestica ENSMODP00000044175 93.3649 90.0474 ENSG00000161960 homo_sapiens ENSP00000293831 99.5074 98.7685 monodelphis_domestica ENSMODP00000008799 99.5074 98.7685 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 bison_bison_bison ENSBBBP00000018737 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 monodon_monoceros ENSMMNP00015022886 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 98.7685 98.2759 sus_scrofa ENSSSCP00000063393 97.8049 97.3171 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 microcebus_murinus ENSMICP00000013457 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 96.798 96.798 octodon_degus ENSODEP00000023927 97.7612 97.7612 ENSG00000161960 homo_sapiens ENSP00000293831 98.0296 98.0296 jaculus_jaculus ENSJJAP00000022845 99.7494 99.7494 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 ovis_aries_rambouillet ENSOARP00020016306 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 98.0296 96.798 ochotona_princeps ENSOPRP00000007875 99.2519 98.005 ENSG00000161960 homo_sapiens ENSP00000293831 96.0591 96.0591 delphinapterus_leucas ENSDLEP00000029464 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 physeter_catodon ENSPCTP00005027541 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 mus_musculus ENSMUSP00000127034 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 dipodomys_ordii ENSDORP00000020139 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 99.7537 99.7537 mustela_putorius_furo ENSMPUP00000009453 99.5086 99.5086 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 aotus_nancymaae ENSANAP00000035729 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 saimiri_boliviensis_boliviensis ENSSBOP00000012977 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 chlorocebus_sabaeus ENSCSAP00000007670 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 camelus_dromedarius ENSCDRP00005011418 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 carlito_syrichta ENSTSYP00000015669 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 98.0296 98.0296 panthera_tigris_altaica ENSPTIP00000012234 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 98.5222 98.2759 rattus_norvegicus ENSRNOP00000049419 97.3236 97.0803 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 prolemur_simus ENSPSMP00000027637 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 microtus_ochrogaster ENSMOCP00000007290 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 sorex_araneus ENSSARP00000005443 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 peromyscus_maniculatus_bairdii ENSPEMP00000007031 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 bos_mutus ENSBMUP00000028539 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 96.798 95.8128 mus_spicilegus ENSMSIP00000036906 98.005 97.0075 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 mus_spicilegus ENSMSIP00000030754 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 cricetulus_griseus_chok1gshd ENSCGRP00001006866 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 99.7537 99.7537 pteropus_vampyrus ENSPVAP00000015377 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 99.7537 myotis_lucifugus ENSMLUP00000003104 99.5098 99.2647 ENSG00000161960 homo_sapiens ENSP00000293831 99.5074 98.7685 vombatus_ursinus ENSVURP00010003898 99.5074 98.7685 ENSG00000161960 homo_sapiens ENSP00000293831 98.5222 98.5222 rhinolophus_ferrumequinum ENSRFEP00010018630 88.3002 88.3002 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 neovison_vison ENSNVIP00000004502 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 bos_taurus ENSBTAP00000000144 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 rhinopithecus_bieti ENSRBIP00000042455 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 canis_lupus_dingo ENSCAFP00020009662 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 sciurus_vulgaris ENSSVLP00005021196 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 99.5074 98.7685 phascolarctos_cinereus ENSPCIP00000039482 99.5074 98.7685 ENSG00000161960 homo_sapiens ENSP00000293831 100 99.7537 procavia_capensis ENSPCAP00000012099 100 99.7537 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 nannospalax_galili ENSNGAP00000018106 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 bos_grunniens ENSBGRP00000025357 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 95.5665 95.5665 cervus_hanglu_yarkandensis ENSCHYP00000026761 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 catagonus_wagneri ENSCWAP00000005310 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 ictidomys_tridecemlineatus ENSSTOP00000031260 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 99.7537 otolemur_garnettii ENSOGAP00000007278 99.5098 99.2647 ENSG00000161960 homo_sapiens ENSP00000293831 66.0098 64.0394 urocitellus_parryii ENSUPAP00010008364 95.7143 92.8571 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 moschus_moschiferus ENSMMSP00000025841 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 rhinopithecus_roxellana ENSRROP00000016040 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 100 100 propithecus_coquereli ENSPCOP00000004245 100 100 ENSG00000161960 homo_sapiens ENSP00000293831 82.5123 68.9655 caenorhabditis_elegans F57B9.6a.1 83.3333 69.6517 ENSG00000161960 homo_sapiens ENSP00000293831 86.9458 72.6601 drosophila_melanogaster FBpp0297911 87.5931 73.201 ENSG00000161960 homo_sapiens ENSP00000293831 88.67 78.3251 ciona_intestinalis ENSCINP00000005836 83.7209 73.9535 ENSG00000161960 homo_sapiens ENSP00000293831 30.2956 26.3547 carassius_auratus ENSCARP00000078280 91.791 79.8507 ENSG00000161960 homo_sapiens ENSP00000293831 98.2759 94.335 xenopus_tropicalis ENSXETP00000078321 97.7941 93.8726 ENSG00000161960 homo_sapiens ENSP00000293831 81.7734 79.803 chrysemys_picta_bellii ENSCPBP00000005884 89.008 86.8633 ENSG00000161960 homo_sapiens ENSP00000293831 97.5369 96.5517 sphenodon_punctatus ENSSPUP00000023877 99.4975 98.4925 ENSG00000161960 homo_sapiens ENSP00000293831 90.6404 89.9015 laticauda_laticaudata ENSLLTP00000010615 99.4595 98.6487 ENSG00000161960 homo_sapiens ENSP00000293831 44.8276 41.8719 pseudonaja_textilis ENSPTXP00000024504 89.2157 83.3333 ENSG00000161960 homo_sapiens ENSP00000293831 27.5862 26.3547 pseudonaja_textilis ENSPTXP00000022350 95.7265 91.453 ENSG00000161960 homo_sapiens ENSP00000293831 17.9803 14.532 anas_platyrhynchos_platyrhynchos ENSAPLP00000005272 52.518 42.446 ENSG00000161960 homo_sapiens ENSP00000293831 37.4384 23.6453 parus_major ENSPMJP00000002422 44.058 27.8261 ENSG00000161960 homo_sapiens ENSP00000293831 40.6404 39.6552 anolis_carolinensis ENSACAP00000025805 47.4138 46.2644 ENSG00000161960 homo_sapiens ENSP00000293831 85.2217 84.2365 naja_naja ENSNNAP00000027982 97.191 96.0674 ENSG00000161960 homo_sapiens ENSP00000293831 98.0296 96.5517 podarcis_muralis ENSPMRP00000018374 93.6471 92.2353 ENSG00000161960 homo_sapiens ENSP00000293831 64.532 60.3448 geospiza_fortis ENSGFOP00000013347 91.9298 85.9649 ENSG00000161960 homo_sapiens ENSP00000293831 58.6207 43.5961 taeniopygia_guttata ENSTGUP00000023825 35.3116 26.2611 ENSG00000161960 homo_sapiens ENSP00000293831 43.8424 30.2956 taeniopygia_guttata ENSTGUP00000035275 38.6117 26.6811 ENSG00000161960 homo_sapiens ENSP00000293831 99.2611 97.7832 salvator_merianae ENSSMRP00000003431 99.2611 97.7832 ENSG00000161960 homo_sapiens ENSP00000293831 98.2759 96.3054 pelodiscus_sinensis ENSPSIP00000009588 88.2743 86.5044 ENSG00000161960 homo_sapiens ENSP00000293831 98.2759 96.3054 gopherus_evgoodei ENSGEVP00005023915 94.3262 92.435 ENSG00000161960 homo_sapiens ENSP00000293831 95.5665 94.335 chelonoidis_abingdonii ENSCABP00000003154 99.4872 98.2051 ENSG00000161960 homo_sapiens ENSP00000293831 15.2709 13.5468 cynoglossus_semilaevis ENSCSEP00000011914 83.7838 74.3243 ENSG00000161960 homo_sapiens ENSP00000293831 85.2217 76.601 myripristis_murdjan ENSMMDP00005044286 91.7772 82.4934 ENSG00000161960 homo_sapiens ENSP00000293831 74.3842 72.6601 terrapene_carolina_triunguis ENSTMTP00000028910 97.4194 95.1613 ENSG00000161960 homo_sapiens ENSP00000293831 87.4384 76.8473 ciona_savignyi ENSCSAVP00000001129 91.0256 80 ENSG00000161960 homo_sapiens ENSP00000293831 92.1182 86.4532 denticeps_clupeoides ENSDCDP00000037510 82.1978 77.1429 ENSG00000161960 homo_sapiens ENSP00000293831 78.0788 59.6059 takifugu_rubripes ENSTRUP00000069002 79.8489 60.9572 ENSG00000161960 homo_sapiens ENSP00000293831 52.2167 43.5961 takifugu_rubripes ENSTRUP00000086211 77.3723 64.5985 ENSG00000161960 homo_sapiens ENSP00000293831 20.936 16.2562 takifugu_rubripes ENSTRUP00000079863 75.2212 58.4071 ENSG00000161960 homo_sapiens ENSP00000293831 80.0493 64.532 takifugu_rubripes ENSTRUP00000068790 80.8458 65.1741 ENSG00000161960 homo_sapiens ENSP00000293831 79.803 62.5616 takifugu_rubripes ENSTRUP00000071395 81.203 63.6591 ENSG00000161960 homo_sapiens ENSP00000293831 89.9015 78.8177 takifugu_rubripes ENSTRUP00000005020 78.8337 69.1145 ENSG00000161960 homo_sapiens ENSP00000293831 20.6897 16.0099 ficedula_albicollis ENSFALP00000028135 62.6866 48.5075 ENSG00000161960 homo_sapiens ENSP00000293831 95.8128 89.6552 cyprinus_carpio_carpio ENSCCRP00000133856 95.8128 89.6552 ENSG00000161960 homo_sapiens ENSP00000293831 96.0591 89.4089 cyprinus_carpio_carpio ENSCCRP00000152773 95.1219 88.5366 ENSG00000161960 homo_sapiens ENSP00000293831 72.9064 60.5911 tetraodon_nigroviridis ENSTNIP00000020212 84.0909 69.8864 ENSG00000161960 homo_sapiens ENSP00000293831 87.1921 69.9507 tetraodon_nigroviridis ENSTNIP00000010211 86.1314 69.0998 ENSG00000161960 homo_sapiens ENSP00000293831 64.0394 47.7833 tetraodon_nigroviridis ENSTNIP00000001247 76.6962 57.2271 ENSG00000161960 homo_sapiens ENSP00000293831 64.532 55.9113 tetraodon_nigroviridis ENSTNIP00000007043 89.726 77.7397 ENSG00000161960 homo_sapiens ENSP00000293831 66.9951 55.665 tetraodon_nigroviridis ENSTNIP00000007000 86.076 71.519 ENSG00000161960 homo_sapiens ENSP00000293831 83.9902 67.4877 tetraodon_nigroviridis ENSTNIP00000009660 88.8021 71.3542 ENSG00000161960 homo_sapiens ENSP00000293831 89.4089 86.2069 leptobrachium_leishanense ENSLLEP00000041985 93.0769 89.7436 ENSG00000161960 homo_sapiens ENSP00000293831 99.0148 95.5665 leptobrachium_leishanense ENSLLEP00000002948 99.0148 95.5665
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000339 enables RNA cap binding 1 TAS Homo_sapiens(9606) Function GO:0002183 involved_in cytoplasmic translational initiation 2 IBA,IDA Homo_sapiens(9606) Process GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0003724 enables RNA helicase activity 1 IEA Homo_sapiens(9606) Function GO:0003725 enables double-stranded RNA binding 1 IDA Homo_sapiens(9606) Function GO:0003729 enables mRNA binding 1 TAS Homo_sapiens(9606) Function GO:0003743 enables translation initiation factor activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0004386 enables helicase activity 1 TAS Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005524 enables ATP binding 1 IEA Homo_sapiens(9606) Function GO:0005634 NOT located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0005829 located_in cytosol 1 TAS Homo_sapiens(9606) Component GO:0006413 involved_in translational initiation 1 NAS Homo_sapiens(9606) Process GO:0008135 enables translation factor activity, RNA binding 1 TAS Homo_sapiens(9606) Function GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0016281 part_of eukaryotic translation initiation factor 4F complex 2 NAS,TAS Homo_sapiens(9606) Component GO:0016887 enables ATP hydrolysis activity 1 IEA Homo_sapiens(9606) Function GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component
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