Ensembl ID ENSG00000161960 Gene ID 1973 Accession 3282
Gene Symbol EIF4A1 Alias DDX2A;EIF4A;EIF-4A;eIF4A-I;eIF-4A-I Full Name eukaryotic translation initiation factor 4A1
Position 17 : 7572825 - 7579006 Length 6182 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Enables double-stranded RNA binding activity. Predicted to be involved in cytoplasmic translational initiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000161960 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000161960 EIF4A1 2.12 4.59e-53 KIRC
ENSG00000161960 EIF4A1 -0.6 1.57e-16 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000161960 EIF4A1 tumor 21114830
ENSG00000161960 EIF4A1 cancers 22415234
ENSG00000161960 EIF4A1 tumor 23872707
ENSG00000161960 EIF4A1 cervical cancer 24844222
ENSG00000161960 EIF4A1 gastric cancer 26936591
ENSG00000161960 EIF4A1 colorectal cancer 28627973
ENSG00000161960 EIF4A1 tumor 28911096
ENSG00000161960 EIF4A1 breast cancers 29844125
ENSG00000161960 EIF4A1 cancer 30132971
ENSG00000161960 EIF4A1 tumors 30821613
ENSG00000161960 EIF4A1 tumor 31088567
ENSG00000161960 EIF4A1 gastric cancer 31190893
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000161960 EIF4A1 STAD 0.017 high
ENSG00000161960 EIF4A1 UVM 0.05 high
ENSG00000161960 EIF4A1 PAAD 0.024 low
ENSG00000161960 EIF4A1 THCA 0.017 high
ENSG00000161960 EIF4A1 ACC 0.002 high
ENSG00000161960 EIF4A1 LGG 0.0032 high
ENSG00000161960 EIF4A1 HNSC 0.0031 low
ENSG00000161960 EIF4A1 READ 0.025 low
ENSG00000161960 EIF4A1 OV 0.027 high
ENSG00000161960 EIF4A1 DLBC 0.001 high
ENSG00000161960 EIF4A1 PRAD 0.0035 high
ENSG00000161960 EIF4A1 BLCA 0.006 low
ENSG00000161960 EIF4A1 SKCM 0.02 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000161960 EIF4A1 SARC Del 18.408539 0.398095 0.598005 0.455253
ENSG00000161960 EIF4A1 GBM Del 4.319272 0.087250 0.505439 0.164645
ENSG00000161960 EIF4A1 LIHC Del 9.402392 0.161227 0.662385 0.605405
ENSG00000161960 EIF4A1 DLBC Del 0.740752 0.126309 0.522682 0.229167
ENSG00000161960 EIF4A1 BRCA Del 2.016677 0.074683 0.490250 0.609259
ENSG00000161960 EIF4A1 PRAD Del 29.998545 0.249978 0.553603 0.323171