Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000158290 Gene ID 8450 Accession 2555
Symbol CUL4B Alias SFM2;MRXSC;CUL-4B;MRXHF2;MRXS15 Full Name cullin 4B
Status Confidence Length 98011 bases Strand Minus strand
Position X : 120505920 - 120603930 RNA binding domain N.A.
Summary This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
31036006 Effect of transcription inhibition and generation of suppressive viral non-coding RNAs. O Daniel Pinto 2019-04-29 Retrovirology
31645981 A novel CUL4B splice site variant in a young male exhibiting less pronounced features. Yuji Nakamura 2019-01-01 Human genome variation

Transcripts

Name Transcript ID bp Protein Translation ID
CUL4B-221 ENST00000680673 24020 913aa ENSP00000505084
CUL4B-227 ENST00000681189 5097 446aa ENSP00000505973
CUL4B-224 ENST00000681080 5081 93aa ENSP00000505898
CUL4B-222 ENST00000680918 4872 121aa ENSP00000505955
CUL4B-202 ENST00000371322 5915 895aa ENSP00000360373
CUL4B-214 ENST00000679927 5899 780aa ENSP00000505603
CUL4B-231 ENST00000681253 5960 913aa ENSP00000506259
CUL4B-203 ENST00000371323 4418 717aa ENSP00000360374
CUL4B-211 ENST00000679405 4599 124aa ENSP00000504985
CUL4B-233 ENST00000681333 7377 401aa ENSP00000505739
CUL4B-201 ENST00000336592 4906 900aa ENSP00000338919
CUL4B-228 ENST00000681206 4981 933aa ENSP00000505480
CUL4B-220 ENST00000680577 5440 No protein -
CUL4B-217 ENST00000680324 6206 No protein -
CUL4B-210 ENST00000674137 5097 897aa ENSP00000501019
CUL4B-218 ENST00000680457 4082 No protein -
CUL4B-208 ENST00000673919 4836 198aa ENSP00000500994
CUL4B-216 ENST00000680165 5430 No protein -
CUL4B-215 ENST00000679965 3206 No protein -
CUL4B-209 ENST00000674073 3897 571aa ENSP00000501262
CUL4B-213 ENST00000679844 3965 675aa ENSP00000505239
CUL4B-225 ENST00000681090 4857 864aa ENSP00000506288
CUL4B-237 ENST00000681706 2656 No protein -
CUL4B-232 ENST00000681263 3469 No protein -
CUL4B-240 ENST00000681908 4215 482aa ENSP00000505777
CUL4B-235 ENST00000681652 5092 913aa ENSP00000505176
CUL4B-234 ENST00000681487 2310 No protein -
CUL4B-212 ENST00000679432 3234 298aa ENSP00000505343
CUL4B-219 ENST00000680474 2545 686aa ENSP00000505562
CUL4B-238 ENST00000681864 5595 No protein -
CUL4B-230 ENST00000681236 1480 No protein -
CUL4B-204 ENST00000404115 2902 844aa ENSP00000384109
CUL4B-207 ENST00000497616 1059 No protein -
CUL4B-236 ENST00000681681 1736 No protein -
CUL4B-239 ENST00000681869 1969 656aa ENSP00000505597
CUL4B-229 ENST00000681224 812 No protein -
CUL4B-205 ENST00000467641 1011 No protein -
CUL4B-206 ENST00000486604 1024 32aa ENSP00000504995
CUL4B-223 ENST00000680988 479 47aa ENSP00000504914
CUL4B-226 ENST00000681148 308 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000158290homo_sapiensENSP0000035814741.734420.0542homo_sapiensENSP0000036037317.20678.26816
ENSG00000158290homo_sapiensENSP0000036458990.909181.8182homo_sapiensENSP0000036037377.09569.3855
ENSG00000158290homo_sapiensENSP0000036388150.201328.5906homo_sapiensENSP0000036037341.787723.7989
ENSG00000158290homo_sapiensENSP0000032680450.515530.5412homo_sapiensENSP0000036037343.798926.4804
ENSG00000158290homo_sapiensENSP0000037680848.589728.3333homo_sapiensENSP0000036037342.346424.6927
ENSG00000158290homo_sapiensENSP0000031400434.793218.1265homo_sapiensENSP0000036037331.955316.648
ENSG00000158290homo_sapiensENSP0000026441458.203138.4115homo_sapiensENSP0000036037349.944132.9609

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000158290homo_sapiensENSP0000036037399.664899.6648nomascus_leucogenysENSNLEP0000004278297.699997.6999
ENSG00000158290homo_sapiensENSP0000036037398.435898.324pan_paniscusENSPPAP0000001086294.527994.4206
ENSG00000158290homo_sapiensENSP0000036037399.664899.6648pongo_abeliiENSPPYP0000003886595.605695.6056
ENSG00000158290homo_sapiensENSP0000036037398.435898.324pan_troglodytesENSPTRP0000003829294.527994.4206
ENSG00000158290homo_sapiensENSP0000036037397.653697.5419gorilla_gorillaENSGGOP0000001089394.079793.972
ENSG00000158290homo_sapiensENSP0000036037394.413491.2849ornithorhynchus_anatinusENSOANP0000004124393.370290.2762
ENSG00000158290homo_sapiensENSP0000036037370.055965.6983sarcophilus_harrisiiENSSHAP0000003847394.570188.6878
ENSG00000158290homo_sapiensENSP0000036037394.301788.8268sarcophilus_harrisiiENSSHAP0000001336293.569888.1375
ENSG00000158290homo_sapiensENSP0000036037364.804564.4693choloepus_hoffmanniENSCHOP0000000809998.305197.7966
ENSG00000158290homo_sapiensENSP0000036037394.301792.1788dasypus_novemcinctusENSDNOP0000000983486.034784.0979
ENSG00000158290homo_sapiensENSP0000036037393.854892.8492erinaceus_europaeusENSEEUP0000001260794.064993.0571
ENSG00000158290homo_sapiensENSP0000036037386.145284.581echinops_telfairiENSETEP0000001657990.49388.8498
ENSG00000158290homo_sapiensENSP0000036037399.553199.4413callithrix_jacchusENSCJAP0000008090696.742796.6341
ENSG00000158290homo_sapiensENSP0000036037399.664899.6648cercocebus_atysENSCATP0000004604697.699997.6999
ENSG00000158290homo_sapiensENSP0000036037399.441399.4413macaca_fascicularisENSMFAP0000003041297.694897.6948
ENSG00000158290homo_sapiensENSP0000036037399.664899.6648macaca_mulattaENSMMUP0000001184995.605695.6056
ENSG00000158290homo_sapiensENSP0000036037399.664899.6648macaca_nemestrinaENSMNEP0000002370397.699997.6999
ENSG00000158290homo_sapiensENSP0000036037397.09596.5363papio_anubisENSPANP0000005470094.972794.4262
ENSG00000158290homo_sapiensENSP0000036037397.653697.5419mandrillus_leucophaeusENSMLEP0000001089793.877593.7701
ENSG00000158290homo_sapiensENSP0000036037390.726390.6145tursiops_truncatusENSTTRP0000000278091.031490.9193
ENSG00000158290homo_sapiensENSP0000036037399.329699.1061vulpes_vulpesENSVVUP0000003946993.776493.5654
ENSG00000158290homo_sapiensENSP0000036037398.547597.4302mus_spretusMGP_SPRETEiJ_P009502090.927889.8969
ENSG00000158290homo_sapiensENSP0000036037398.77197.9888equus_asinusENSEASP0000500372688.75588.0522
ENSG00000158290homo_sapiensENSP0000036037399.106198.5475capra_hircusENSCHIP0000002478586.368185.8812
ENSG00000158290homo_sapiensENSP0000036037398.882798.4358loxodonta_africanaENSLAFP0000002082393.551893.129
ENSG00000158290homo_sapiensENSP0000036037399.106198.9944panthera_leoENSPLOP0000002694997.365597.2558
ENSG00000158290homo_sapiensENSP0000036037399.441399.1061ailuropoda_melanoleucaENSAMEP0000003027497.587797.2588
ENSG00000158290homo_sapiensENSP0000036037398.994498.5475bos_indicus_hybridENSBIXP0000503709196.409195.9739
ENSG00000158290homo_sapiensENSP0000036037361.787760.4469bos_indicus_hybridENSBIXP0000503265394.207892.1635
ENSG00000158290homo_sapiensENSP0000036037399.329699.1061oryctolagus_cuniculusENSOCUP0000004045298.668198.4462
ENSG00000158290homo_sapiensENSP0000036037398.547597.8771equus_caballusENSECAP0000006113488.554287.9518
ENSG00000158290homo_sapiensENSP0000036037399.217998.9944canis_lupus_familiarisENSCAFP0084503203887.144386.948
ENSG00000158290homo_sapiensENSP0000036037399.106198.9944panthera_pardusENSPPRP0000000257197.365597.2558
ENSG00000158290homo_sapiensENSP0000036037396.536396.3129marmota_marmota_marmotaENSMMMP0000000729499.769199.5381
ENSG00000158290homo_sapiensENSP0000036037399.329699.1061balaenoptera_musculusENSBMSP0001002344798.558898.337
ENSG00000158290homo_sapiensENSP0000036037398.77198.2123cavia_porcellusENSCPOP0000002546694.444493.9103
ENSG00000158290homo_sapiensENSP0000036037399.217998.9944felis_catusENSFCAP0000002671997.475397.2558
ENSG00000158290homo_sapiensENSP0000036037394.972194.1899ursus_americanusENSUAMP0000000893096.700895.9044
ENSG00000158290homo_sapiensENSP0000036037369.385565.8101monodelphis_domesticaENSMODP0000004730294.664689.7866
ENSG00000158290homo_sapiensENSP0000036037393.74388.7151monodelphis_domesticaENSMODP0000005495578.411274.2056
ENSG00000158290homo_sapiensENSP0000036037399.329699.1061monodon_monocerosENSMMNP0001502453797.478197.2588
ENSG00000158290homo_sapiensENSP0000036037399.106198.6592sus_scrofaENSSSCP0000001340183.679283.3019
ENSG00000158290homo_sapiensENSP0000036037399.441399.3296microcebus_murinusENSMICP0000001648797.587797.4781
ENSG00000158290homo_sapiensENSP0000036037399.329698.771octodon_degusENSODEP0000000092299.329698.771
ENSG00000158290homo_sapiensENSP0000036037392.402290.838jaculus_jaculusENSJJAP0000000768988.829287.3255
ENSG00000158290homo_sapiensENSP0000036037399.217998.6592ovis_aries_rambouilletENSOARP0002002809186.803586.3148
ENSG00000158290homo_sapiensENSP0000036037393.74392.6257ursus_maritimusENSUMAP0000003169893.74392.6257
ENSG00000158290homo_sapiensENSP0000036037350.614550.1676ochotona_princepsENSOPRP0000001570466.912866.322
ENSG00000158290homo_sapiensENSP0000036037353.072650.9497delphinapterus_leucasENSDLEP0000002073290.822287.1893
ENSG00000158290homo_sapiensENSP0000036037395.642595.0838delphinapterus_leucasENSDLEP0000002612597.716997.1461
ENSG00000158290homo_sapiensENSP0000036037399.329699.1061physeter_catodonENSPCTP0000503039098.449698.2281
ENSG00000158290homo_sapiensENSP0000036037344.134142.905physeter_catodonENSPCTP0000502016289.977287.4715
ENSG00000158290homo_sapiensENSP0000036037398.547597.4302mus_caroliMGP_CAROLIEiJ_P009126390.461589.4359
ENSG00000158290homo_sapiensENSP0000036037398.547597.4302mus_musculusENSMUSP0000011077190.927889.8969
ENSG00000158290homo_sapiensENSP0000036037387.93386.7039dipodomys_ordiiENSDORP0000001128390.355989.093
ENSG00000158290homo_sapiensENSP0000036037399.329698.9944mustela_putorius_furoENSMPUP0000000140785.398785.1105
ENSG00000158290homo_sapiensENSP0000036037397.765497.5419aotus_nancymaaeENSANAP0000004087493.383193.1697
ENSG00000158290homo_sapiensENSP0000036037399.441399.4413saimiri_boliviensis_boliviensisENSSBOP0000002626997.587797.5877
ENSG00000158290homo_sapiensENSP0000036037391.173290.838vicugna_pacosENSVPAP0000000165989.375789.0471
ENSG00000158290homo_sapiensENSP0000036037399.664899.5531chlorocebus_sabaeusENSCSAP0000001434799.111199
ENSG00000158290homo_sapiensENSP0000036037396.983296.3129tupaia_belangeriENSTBEP0000000645395.175494.5175
ENSG00000158290homo_sapiensENSP0000036037360.223559.5531mesocricetus_auratusENSMAUP0000000276797.117196.036
ENSG00000158290homo_sapiensENSP0000036037350.502848.8268phocoena_sinusENSPSNP0000001216791.869988.8211
ENSG00000158290homo_sapiensENSP0000036037399.329699.1061phocoena_sinusENSPSNP0000002525997.371397.1522
ENSG00000158290homo_sapiensENSP0000036037399.441399.2179camelus_dromedariusENSCDRP0000502077897.374297.1554
ENSG00000158290homo_sapiensENSP0000036037354.189953.743carlito_syrichtaENSTSYP0000002558697.389696.5863
ENSG00000158290homo_sapiensENSP0000036037399.329699.1061carlito_syrichtaENSTSYP0000001960097.692397.4725
ENSG00000158290homo_sapiensENSP0000036037396.201195.3073panthera_tigris_altaicaENSPTIP0000001040997.729996.8218
ENSG00000158290homo_sapiensENSP0000036037398.994498.1006rattus_norvegicusENSRNOP0000006063991.246190.4222
ENSG00000158290homo_sapiensENSP0000036037398.994498.6592prolemur_simusENSPSMP0000001721396.409196.0827
ENSG00000158290homo_sapiensENSP0000036037398.547597.2067microtus_ochrogasterENSMOCP0000001894591.209989.969
ENSG00000158290homo_sapiensENSP0000036037393.296189.9441microtus_ochrogasterENSMOCP0000001229291.356788.0744
ENSG00000158290homo_sapiensENSP0000036037360.893960.4469sorex_araneusENSSARP0000000160786.370885.7369
ENSG00000158290homo_sapiensENSP0000036037398.994497.9888peromyscus_maniculatus_bairdiiENSPEMP0000000678691.434590.5057
ENSG00000158290homo_sapiensENSP0000036037398.659298.2123bos_mutusENSBMUP0000003018196.397495.9607
ENSG00000158290homo_sapiensENSP0000036037376.759875.5307mus_spicilegusENSMSIP0000003515095.020793.4993
ENSG00000158290homo_sapiensENSP0000036037347.374345.8101cricetulus_griseus_chok1gshdENSCGRP0000100909592.77989.7155
ENSG00000158290homo_sapiensENSP0000036037398.212397.3184cricetulus_griseus_chok1gshdENSCGRP0000100109190.618689.7938
ENSG00000158290homo_sapiensENSP0000036037392.06791.9553pteropus_vampyrusENSPVAP0000000180892.688492.5759
ENSG00000158290homo_sapiensENSP0000036037399.329698.771myotis_lucifugusENSMLUP0000001204999.218898.6607
ENSG00000158290homo_sapiensENSP0000036037365.363159.6648vombatus_ursinusENSVURP0001002920692.271384.2271
ENSG00000158290homo_sapiensENSP0000036037394.525189.8324vombatus_ursinusENSVURP0001001968893.480788.8398
ENSG00000158290homo_sapiensENSP0000036037399.553199.1061rhinolophus_ferrumequinumENSRFEP0001000344896.637796.2039
ENSG00000158290homo_sapiensENSP0000036037393.184492.6257neovison_visonENSNVIP0000002966195.972495.397
ENSG00000158290homo_sapiensENSP0000036037398.882798.4358bos_taurusENSBTAP0000006040396.405295.9695
ENSG00000158290homo_sapiensENSP0000036037357.765455.0838heterocephalus_glaber_femaleENSHGLP0000000614490.861286.6432
ENSG00000158290homo_sapiensENSP0000036037337.318434.8603heterocephalus_glaber_femaleENSHGLP0000000321986.753381.039
ENSG00000158290homo_sapiensENSP0000036037392.849292.4022heterocephalus_glaber_femaleENSHGLP0000000103298.928698.4524
ENSG00000158290homo_sapiensENSP0000036037355.642554.3017heterocephalus_glaber_femaleENSHGLP0000005556793.258491.0112
ENSG00000158290homo_sapiensENSP0000036037327.93327.0391rhinopithecus_bietiENSRBIP0000001580489.285786.4286
ENSG00000158290homo_sapiensENSP0000036037331.843630.838rhinopithecus_bietiENSRBIP0000002733495.317792.3077
ENSG00000158290homo_sapiensENSP0000036037399.441399.1061canis_lupus_dingoENSCAFP0002000473298.888998.5556
ENSG00000158290homo_sapiensENSP0000036037399.553199.4413sciurus_vulgarisENSSVLP0000501722797.590497.4808
ENSG00000158290homo_sapiensENSP0000036037380.782179.8883sciurus_vulgarisENSSVLP0000502083596.916995.8445
ENSG00000158290homo_sapiensENSP0000036037394.748690.0559phascolarctos_cinereusENSPCIP0000003939892.475587.8953
ENSG00000158290homo_sapiensENSP0000036037379.329678.4358procavia_capensisENSPCAP0000000181077.850976.9737
ENSG00000158290homo_sapiensENSP0000036037398.32497.2067nannospalax_galiliENSNGAP0000001082898.43497.3154
ENSG00000158290homo_sapiensENSP0000036037397.988897.3184chinchilla_lanigeraENSCLAP0000000018194.504393.8578
ENSG00000158290homo_sapiensENSP0000036037385.921882.3464chinchilla_lanigeraENSCLAP0000001208490.364386.604
ENSG00000158290homo_sapiensENSP0000036037399.106198.8827cervus_hanglu_yarkandensisENSCHYP0000002244695.47995.2637
ENSG00000158290homo_sapiensENSP0000036037399.553199.2179catagonus_wagneriENSCWAP0000000210998.780598.4479
ENSG00000158290homo_sapiensENSP0000036037310099.5531ictidomys_tridecemlineatusENSSTOP0000001686192.26891.8557
ENSG00000158290homo_sapiensENSP0000036037397.653696.5363otolemur_garnettiiENSOGAP0000000114598.312797.1879
ENSG00000158290homo_sapiensENSP0000036037397.541997.3184cebus_imitatorENSCCAP0000000928193.169792.9562
ENSG00000158290homo_sapiensENSP0000036037375.754273.9665urocitellus_parryiiENSUPAP0001000353994.166791.9444
ENSG00000158290homo_sapiensENSP0000036037398.547598.324moschus_moschiferusENSMMSP0000000730696.498996.2801
ENSG00000158290homo_sapiensENSP0000036037399.664899.6648rhinopithecus_roxellanaENSRROP0000001231397.699997.6999
ENSG00000158290homo_sapiensENSP0000036037365.921865.4749mus_pahariMGP_PahariEiJ_P008890899.326698.6532
ENSG00000158290homo_sapiensENSP0000036037356.759856.7598propithecus_coquereliENSPCOP0000001422399.803599.8035
ENSG00000158290homo_sapiensENSP0000036037338.435822.5698caenorhabditis_elegansZK856.1.144.967326.4052
ENSG00000158290homo_sapiensENSP000003603734022.3464drosophila_melanogasterFBpp008478642.018823.4742
ENSG00000158290homo_sapiensENSP000003603736.033522.68156ciona_intestinalisENSCINP0000000626040.601518.0451
ENSG00000158290homo_sapiensENSP0000036037321.005612.6257ciona_intestinalisENSCINP0000000625451.790631.1295
ENSG00000158290homo_sapiensENSP0000036037363.798958.5475petromyzon_marinusENSPMAP0000000693292.694885.0649
ENSG00000158290homo_sapiensENSP0000036037372.06762.0112eptatretus_burgeriENSEBUP0000000814682.480870.9719
ENSG00000158290homo_sapiensENSP0000036037379.553176.2011callorhinchus_miliiENSCMIP0000003478894.304690.3311
ENSG00000158290homo_sapiensENSP0000036037389.944185.8101latimeria_chalumnaeENSLACP0000000530995.266390.8876
ENSG00000158290homo_sapiensENSP0000036037390.055984.6927lepisosteus_oculatusENSLOCP0000001876993.28787.7315
ENSG00000158290homo_sapiensENSP0000036037386.815681.8994clupea_harengusENSCHAP0000004441088.395983.3902
ENSG00000158290homo_sapiensENSP0000036037388.826883.7989danio_rerioENSDARP0000012426792.013986.8056
ENSG00000158290homo_sapiensENSP0000036037385.363179.3296carassius_auratusENSCARP0000012845384.983378.9766
ENSG00000158290homo_sapiensENSP0000036037387.262682.0112carassius_auratusENSCARP0000001426886.681581.465
ENSG00000158290homo_sapiensENSP0000036037387.709582.4581carassius_auratusENSCARP0000003196890.437885.023
ENSG00000158290homo_sapiensENSP0000036037385.586680.2235astyanax_mexicanusENSAMXP0000000023189.800784.1735
ENSG00000158290homo_sapiensENSP0000036037367.039164.9162astyanax_mexicanusENSAMXP0000004871294.488291.4961
ENSG00000158290homo_sapiensENSP0000036037388.156484.0223ictalurus_punctatusENSIPUP0000002825992.388888.0562
ENSG00000158290homo_sapiensENSP0000036037387.597881.4525esox_luciusENSELUP0000007865591.481985.0642
ENSG00000158290homo_sapiensENSP0000036037386.368781.229electrophorus_electricusENSEEEP0000003041989.675284.3387
ENSG00000158290homo_sapiensENSP0000036037385.698379.4413oncorhynchus_kisutchENSOKIP0000507199089.082582.5784
ENSG00000158290homo_sapiensENSP0000036037387.374381.5642oncorhynchus_kisutchENSOKIP0000506222190.092284.1014
ENSG00000158290homo_sapiensENSP0000036037386.368780.2235oncorhynchus_mykissENSOMYP0000008399987.344681.1299
ENSG00000158290homo_sapiensENSP0000036037387.709582.0112oncorhynchus_mykissENSOMYP0000010346987.513981.8283
ENSG00000158290homo_sapiensENSP0000036037387.374381.3408salmo_salarENSSSAP0000000638088.561782.4462
ENSG00000158290homo_sapiensENSP0000036037383.463777.5419salmo_salarENSSSAP0000010178387.266481.0748
ENSG00000158290homo_sapiensENSP0000036037387.709581.8994salmo_truttaENSSTUP0000000496189.714383.7714
ENSG00000158290homo_sapiensENSP0000036037387.48681.4525salmo_truttaENSSTUP0000004809090.207483.9862
ENSG00000158290homo_sapiensENSP0000036037387.597882.0112gadus_morhuaENSGMOP0000005033489.395783.6944
ENSG00000158290homo_sapiensENSP0000036037389.050382.905fundulus_heteroclitusENSFHEP0000003165491.820385.4839
ENSG00000158290homo_sapiensENSP0000036037389.720783.6871poecilia_reticulataENSPREP0000001777892.087285.8945
ENSG00000158290homo_sapiensENSP0000036037389.273783.5754xiphophorus_maculatusENSXMAP0000001366092.156986.2745
ENSG00000158290homo_sapiensENSP0000036037385.474979.1061oryzias_latipesENSORLP0000000136990.532583.787
ENSG00000158290homo_sapiensENSP0000036037381.340875.6425cyclopterus_lumpusENSCLMP0000500937487.922781.7633
ENSG00000158290homo_sapiensENSP0000036037388.603482.6816oreochromis_niloticusENSONIP0000003066491.254385.1553
ENSG00000158290homo_sapiensENSP0000036037388.156482.5698haplochromis_burtoniENSHBUP0000001527891.213985.4335
ENSG00000158290homo_sapiensENSP0000036037388.044782.3464astatotilapia_callipteraENSACLP0000000199888.4482.716
ENSG00000158290homo_sapiensENSP0000036037388.491683.352sparus_aurataENSSAUP0001004310184.705979.7861
ENSG00000158290homo_sapiensENSP0000036037389.273783.352lates_calcariferENSLCAP0001005432387.227181.441
ENSG00000158290homo_sapiensENSP0000036037389.385584.2458xenopus_tropicalisENSXETP0000000970589.086983.9644
ENSG00000158290homo_sapiensENSP0000036037394.189990.3911chrysemys_picta_belliiENSCPBP0000001749495.4791.6195
ENSG00000158290homo_sapiensENSP0000036037394.301790.5028sphenodon_punctatusENSSPUP0000001674495.04591.2162
ENSG00000158290homo_sapiensENSP0000036037394.301790.5028crocodylus_porosusENSCPRP0000500812789.882986.262
ENSG00000158290homo_sapiensENSP0000036037394.189990.838laticauda_laticaudataENSLLTP0000000476991.630488.3696
ENSG00000158290homo_sapiensENSP0000036037394.301790.838notechis_scutatusENSNSUP0000001341091.83988.4657
ENSG00000158290homo_sapiensENSP0000036037392.849289.4972pseudonaja_textilisENSPTXP0000001855092.43689.099
ENSG00000158290homo_sapiensENSP0000036037394.189990.838pseudonaja_textilisENSPTXP0000001865491.630488.3696
ENSG00000158290homo_sapiensENSP0000036037394.413490.7263anas_platyrhynchos_platyrhynchosENSAPLP0000002041195.372591.6479
ENSG00000158290homo_sapiensENSP0000036037390.167686.4804gallus_gallusENSGALP0001001709794.941291.0588
ENSG00000158290homo_sapiensENSP0000036037394.189990.6145meleagris_gallopavoENSMGAP0000000774695.36291.7421
ENSG00000158290homo_sapiensENSP0000036037394.525190.5028serinus_canariaENSSCAP0000002367295.377791.3191
ENSG00000158290homo_sapiensENSP0000036037394.525190.6145parus_majorENSPMJP0000001500395.377791.4318
ENSG00000158290homo_sapiensENSP0000036037393.519688.3799anolis_carolinensisENSACAP0000001058393.31188.1828
ENSG00000158290homo_sapiensENSP0000036037326.033525.1397neolamprologus_brichardiENSNBRP0000001470494.33291.0931
ENSG00000158290homo_sapiensENSP0000036037388.491685.5866naja_najaENSNNAP0000002558094.285791.1905
ENSG00000158290homo_sapiensENSP0000036037394.189990.1676podarcis_muralisENSPMRP0000003025686.372982.6844
ENSG00000158290homo_sapiensENSP0000036037394.525190.6145geospiza_fortisENSGFOP0000002130595.377791.4318
ENSG00000158290homo_sapiensENSP0000036037394.636990.7263taeniopygia_guttataENSTGUP0000000365895.382991.4414
ENSG00000158290homo_sapiensENSP0000036037387.597881.5642erpetoichthys_calabaricusENSECRP0000001824687.305181.2918
ENSG00000158290homo_sapiensENSP0000036037389.385583.4637kryptolebias_marmoratusENSKMAP0000000048092.059885.9609
ENSG00000158290homo_sapiensENSP0000036037394.078289.8324salvator_merianaeENSSMRP0000002287192.527588.3516
ENSG00000158290homo_sapiensENSP0000036037388.044782.1229oryzias_javanicusENSOJAP0000003772985.005479.288
ENSG00000158290homo_sapiensENSP0000036037388.044782.3464amphilophus_citrinellusENSACIP0000001710392.056186.0981
ENSG00000158290homo_sapiensENSP0000036037386.480480.7821dicentrarchus_labraxENSDLAP0000500902084.961679.3633
ENSG00000158290homo_sapiensENSP0000036037388.826883.4637amphiprion_perculaENSAPEP0000000808392.120586.5585
ENSG00000158290homo_sapiensENSP0000036037387.597881.5642oryzias_sinensisENSOSIP0000004802787.402581.3824
ENSG00000158290homo_sapiensENSP0000036037393.631389.9441pelodiscus_sinensisENSPSIP0000001900891.785388.1709
ENSG00000158290homo_sapiensENSP0000036037394.301790.6145chelonoidis_abingdoniiENSCABP0000002379095.583291.846
ENSG00000158290homo_sapiensENSP0000036037384.804579.1061seriola_dumeriliENSSDUP0000000800091.007284.8921
ENSG00000158290homo_sapiensENSP0000036037387.262681.229cottoperca_gobioENSCGOP0000003918987.556181.5022
ENSG00000158290homo_sapiensENSP0000036037394.525190.838struthio_camelus_australisENSSCUP0000000866895.485391.7607
ENSG00000158290homo_sapiensENSP0000036037394.413490.7263anser_brachyrhynchusENSABRP0000000701095.372591.6479
ENSG00000158290homo_sapiensENSP0000036037387.150881.4525gasterosteus_aculeatusENSGACP0000002300991.656985.6639
ENSG00000158290homo_sapiensENSP0000036037383.463777.5419cynoglossus_semilaevisENSCSEP0000000323390.545584.1212
ENSG00000158290homo_sapiensENSP0000036037389.273783.4637poecilia_formosaENSPFOP0000001739392.050786.0599
ENSG00000158290homo_sapiensENSP0000036037387.48682.1229myripristis_murdjanENSMMDP0000503621088.977383.5227
ENSG00000158290homo_sapiensENSP0000036037387.262682.1229sander_luciopercaENSSLUP0000005033486.874381.7575
ENSG00000158290homo_sapiensENSP0000036037394.525190.7263strigops_habroptilaENSSHBP0000501736395.377791.5445
ENSG00000158290homo_sapiensENSP0000036037388.938583.5754amphiprion_ocellarisENSAOCP0000000726592.129686.5741
ENSG00000158290homo_sapiensENSP0000036037386.815682.7933terrapene_carolina_triunguisENSTMTP0000001228488.095284.0136
ENSG00000158290homo_sapiensENSP0000036037386.592280hucho_huchoENSHHUP0000004555589.18382.3936
ENSG00000158290homo_sapiensENSP0000036037385.139778.2123hucho_huchoENSHHUP0000008957484.29277.4336
ENSG00000158290homo_sapiensENSP0000036037384.692778.8827betta_splendensENSBSLP0000005106383.02377.3275
ENSG00000158290homo_sapiensENSP0000036037388.268283.9106pygocentrus_nattereriENSPNAP0000001517191.967487.4272
ENSG00000158290homo_sapiensENSP0000036037388.715183.4637anabas_testudineusENSATEP0000006749986.96681.8182
ENSG00000158290homo_sapiensENSP0000036037338.994421.676ciona_savignyiENSCSAVP0000001865845.442725.2604
ENSG00000158290homo_sapiensENSP0000036037389.385583.5754seriola_lalandi_dorsalisENSSLDP0000000372791.848485.8783
ENSG00000158290homo_sapiensENSP0000036037389.050383.352labrus_bergyltaENSLBEP0000003848691.399185.5505
ENSG00000158290homo_sapiensENSP0000036037388.156482.4581pundamilia_nyerereiENSPNYP0000001326491.213985.3179
ENSG00000158290homo_sapiensENSP0000036037373.631371.0615mastacembelus_armatusENSMAMP0000002988595.507292.1739
ENSG00000158290homo_sapiensENSP0000036037385.921879.8883stegastes_partitusENSSPAP0000001301089.731683.4306
ENSG00000158290homo_sapiensENSP0000036037385.586679.3296oncorhynchus_tshawytschaENSOTSP0000500471588.966382.4622
ENSG00000158290homo_sapiensENSP0000036037387.48681.5642oncorhynchus_tshawytschaENSOTSP0000504755771.966967.0956
ENSG00000158290homo_sapiensENSP0000036037386.145280.1117acanthochromis_polyacanthusENSAPOP0000001008588.824982.6037
ENSG00000158290homo_sapiensENSP0000036037391.284987.3743aquila_chrysaetos_chrysaetosENSACCP0002001506489.094985.2781
ENSG00000158290homo_sapiensENSP0000036037389.497283.1285nothobranchius_furzeriENSNFUP0001500167793.031486.4111
ENSG00000158290homo_sapiensENSP0000036037388.715182.5698cyprinodon_variegatusENSCVAP0000000389592.004685.6315
ENSG00000158290homo_sapiensENSP0000036037386.145280.6704denticeps_clupeoidesENSDCDP0000005059990.28184.5433
ENSG00000158290homo_sapiensENSP0000036037387.93383.2402larimichthys_croceaENSLCRP0000504731985.91781.3319
ENSG00000158290homo_sapiensENSP0000036037387.709582.4581takifugu_rubripesENSTRUP0000006160885.886280.744
ENSG00000158290homo_sapiensENSP0000036037394.636990.6145ficedula_albicollisENSFALP0000000159595.382991.3288
ENSG00000158290homo_sapiensENSP0000036037381.899477.4302hippocampus_comesENSHCOP0000001204094.948289.7668
ENSG00000158290homo_sapiensENSP0000036037387.821282.3464cyprinus_carpio_carpioENSCCRP0000017654389.014783.4655
ENSG00000158290homo_sapiensENSP0000036037388.044782.6816cyprinus_carpio_carpioENSCCRP0000009537289.545584.0909
ENSG00000158290homo_sapiensENSP0000036037393.966590.0559coturnix_japonicaENSCJPP0000502377895.135791.1765
ENSG00000158290homo_sapiensENSP0000036037389.385583.5754poecilia_latipinnaENSPLAP0000001605292.165986.1751
ENSG00000158290homo_sapiensENSP0000036037386.368781.3408sinocyclocheilus_grahamiENSSGRP0000011003887.24682.167
ENSG00000158290homo_sapiensENSP0000036037378.77172.2905sinocyclocheilus_grahamiENSSGRP0000005400185.454578.4242
ENSG00000158290homo_sapiensENSP0000036037388.044782.4581maylandia_zebraENSMZEP0000501030491.309485.5156
ENSG00000158290homo_sapiensENSP0000036037387.262681.7877tetraodon_nigroviridisENSTNIP0000000321590.919785.2154
ENSG00000158290homo_sapiensENSP0000036037332.290530.7263tetraodon_nigroviridisENSTNIP0000000421981.638477.6836
ENSG00000158290homo_sapiensENSP0000036037389.944184.2458paramormyrops_kingsleyaeENSPKIP0000003435193.822887.8788
ENSG00000158290homo_sapiensENSP0000036037385.698379.6648scleropages_formosusENSSFOP0001504810177.396671.9475
ENSG00000158290homo_sapiensENSP0000036037389.273783.5754scleropages_formosusENSSFOP0001505514088.482882.835
ENSG00000158290homo_sapiensENSP0000036037388.826883.5754leptobrachium_leishanenseENSLLEP0000002816290.649985.2908
ENSG00000158290homo_sapiensENSP0000036037389.050383.352scophthalmus_maximusENSSMAP0000006234189.651383.9145
ENSG00000158290homo_sapiensENSP0000036037388.379982.3464oryzias_melastigmaENSOMEP0000003058591.550985.3009

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000082involved_in G1/S transition of mitotic cell cycle1NASHomo_sapiens(9606)Process
GO:0000209involved_in protein polyubiquitination1IEAHomo_sapiens(9606)Process
GO:0003684contributes_to damaged DNA binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006511involved_in ubiquitin-dependent protein catabolic process1IEAHomo_sapiens(9606)Process
GO:0006974involved_in DNA damage response2IBA,ISSHomo_sapiens(9606)Process
GO:0010467involved_in gene expression1IEAHomo_sapiens(9606)Process
GO:0010498acts_upstream_of_or_within proteasomal protein catabolic process2IDA,IMPHomo_sapiens(9606)Process
GO:0016567involved_in protein ubiquitination2IBA,IMPHomo_sapiens(9606)Process
GO:0031175involved_in neuron projection development1IEAHomo_sapiens(9606)Process
GO:0031464part_of Cul4A-RING E3 ubiquitin ligase complex1EXPHomo_sapiens(9606)Component
GO:0031465part_of Cul4B-RING E3 ubiquitin ligase complex2IBA,IDAHomo_sapiens(9606)Component
GO:0031625enables ubiquitin protein ligase binding1IBAHomo_sapiens(9606)Function
GO:0034644involved_in cellular response to UV1ISSHomo_sapiens(9606)Process
GO:0042254involved_in ribosome biogenesis1IMPHomo_sapiens(9606)Process
GO:0045732involved_in positive regulation of protein catabolic process1IEAHomo_sapiens(9606)Process
GO:0048708involved_in astrocyte differentiation1IEAHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070914involved_in UV-damage excision repair1IDAHomo_sapiens(9606)Process
GO:0080008part_of Cul4-RING E3 ubiquitin ligase complex1IDAHomo_sapiens(9606)Component
GO:1900087involved_in positive regulation of G1/S transition of mitotic cell cycle1IEAHomo_sapiens(9606)Process

Expression