Ensembl ID
ENSG00000158290
Gene ID
8450
Accession
2555
Gene Symbol
CUL4B
Alias
SFM2;MRXSC;CUL-4B;MRXHF2;MRXS15
Full Name
cullin 4B
Position
X : 120505920 - 120603930
Length
98011 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
ENSG00000158290 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000158290
CUL4B
0.46
1.15e-12
LUSC
ENSG00000158290
CUL4B
0.39
1.74e-11
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000158290
CUL4B
tumor
20075607
ENSG00000158290
CUL4B
tumor
22649780
ENSG00000158290
CUL4B
cancer
23227454
ENSG00000158290
CUL4B
cancers
23238014
ENSG00000158290
CUL4B
colon cancer
23649548
ENSG00000158290
CUL4B
cancer
23802180
ENSG00000158290
CUL4B
tumor
24292684
ENSG00000158290
CUL4B
breast cancer
24884718
ENSG00000158290
CUL4B
tumour
25430888
ENSG00000158290
CUL4B
cancer
25664533
ENSG00000158290
CUL4B
brain tumors
25855927
ENSG00000158290
CUL4B
cancer
25883150
ENSG00000158290
CUL4B
liver tumors
25945838
ENSG00000158290
CUL4B
Tumor
26450912
ENSG00000158290
CUL4B
cancer
26460955
ENSG00000158290
CUL4B
colorectal cancer
26617747
ENSG00000158290
CUL4B
Non-Small Cell Lung Cancer
27656838
ENSG00000158290
CUL4B
Lung Cancer
27974468
ENSG00000158290
CUL4B
tumor
28164432
ENSG00000158290
CUL4B
cancers
28446751
ENSG00000158290
CUL4B
tumor
28465351
ENSG00000158290
CUL4B
cancers
28630798
ENSG00000158290
CUL4B
pancreatic cancer
28685847
ENSG00000158290
CUL4B
bladder cancer
29100384
ENSG00000158290
CUL4B
gastric cancer
29106389
ENSG00000158290
CUL4B
pancreatic cancer
29274277
ENSG00000158290
CUL4B
tumor
29377600
ENSG00000158290
CUL4B
gastric cancer
29393470
ENSG00000158290
CUL4B
tumor
29499938
ENSG00000158290
CUL4B
tumor
29581734
ENSG00000158290
CUL4B
cancer
29738775
ENSG00000158290
CUL4B
breast cancer
29846670
ENSG00000158290
CUL4B
colorectal cancer
29863249
ENSG00000158290
CUL4B
colorectal cancer
30178820
ENSG00000158290
CUL4B
tumor
30229816
ENSG00000158290
CUL4B
gastric cancer
30483755
ENSG00000158290
CUL4B
prostate cancer
30609075
ENSG00000158290
CUL4B
cancers
30612524
ENSG00000158290
CUL4B
tumor
30872583
ENSG00000158290
CUL4B
tumors
30883036
ENSG00000158290
CUL4B
tumour
30945288
ENSG00000158290
CUL4B
cancer
31111526
ENSG00000158290
CUL4B
cancer
31235785
ENSG00000158290
CUL4B
breast cancer
31374029
ENSG00000158290
CUL4B
non-small cell lung cancer
31407591
ENSG00000158290
CUL4B
lung cancer
31448526
ENSG00000158290
CUL4B
tumor
31598391
ENSG00000158290
CUL4B
cancer
31690264
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000158290
CUL4B
STAD
0.044
high
show
ENSG00000158290
CUL4B
UCEC
0.0039
high
show
ENSG00000158290
CUL4B
ACC
0.04
low
show
ENSG00000158290
CUL4B
LGG
0.0076
high
show
ENSG00000158290
CUL4B
LUSC
0.045
low
show
ENSG00000158290
CUL4B
KICH
0.00029
high
show
ENSG00000158290
CUL4B
LUAD
0.0015
high
show
ENSG00000158290
CUL4B
BRCA
0.036
high
show
ENSG00000158290
CUL4B
DLBC
0.015
high
show
ENSG00000158290
CUL4B
KIRC
0.00059
low
show
ENSG00000158290
CUL4B
PRAD
0.035
high
show
ENSG00000158290
CUL4B
LAML
0.033
low
show
ENSG00000158290
CUL4B
GBM
0.032
low
show
ENSG00000158290
CUL4B
SKCM
0.035
low
show
ENSG00000158290
CUL4B
CESC
0.024
low
show
ENSG00000158290
CUL4B
LIHC
0.0038
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
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