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RBP World!
Functions and Diseases
RBP Type | Canonical_RBPs |
Diseases | CancerSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVDengueZika |
Drug | Drug |
Main interacting RNAs | rRNA |
Moonlighting functions | Metabolic enzyme |
Localizations | Stress granucleP-body |
BulkPerturb-seq | DataSet_02_106 |
Description
Ensembl ID | ENSG00000149273 | Gene ID | 6188 | Accession | 10420 |
Symbol | RPS3 | Alias | S3;uS3 | Full Name | ribosomal protein S3 |
Status | Confidence | Length | 22763 bases | Strand | Plus strand |
Position | 11 : 75399518 - 75422280 | RNA binding domain | KH_2 , Ribosomal_S3_C | ||
Summary | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
RNA binding domains (RBDs)
Protein | Domain | Pfam ID | E-value | Domain number |
---|---|---|---|---|
ENSP00000433155 | KH_2 | PF07650 | 1.9e-11 | 1 |
ENSP00000437105 | KH_2 | PF07650 | 2.2e-11 | 1 |
ENSP00000431737 | KH_2 | PF07650 | 2.7e-11 | 1 |
ENSP00000436335 | KH_2 | PF07650 | 4.4e-11 | 1 |
ENSP00000433821 | KH_2 | PF07650 | 8.8e-11 | 1 |
ENSP00000433821 | Ribosomal_S3_C | PF00189 | 5.8e-23 | 2 |
ENSP00000434643 | KH_2 | PF07650 | 8.8e-11 | 1 |
ENSP00000434643 | Ribosomal_S3_C | PF00189 | 5.8e-23 | 2 |
ENSP00000436971 | KH_2 | PF07650 | 8.8e-11 | 1 |
ENSP00000436971 | Ribosomal_S3_C | PF00189 | 5.8e-23 | 2 |
ENSP00000278572 | KH_2 | PF07650 | 4.2e-10 | 1 |
ENSP00000278572 | Ribosomal_S3_C | PF00189 | 6.8e-23 | 2 |
ENSP00000432542 | KH_2 | PF07650 | 6.7e-10 | 1 |
ENSP00000431834 | KH_2 | PF07650 | 1.2e-09 | 1 |
ENSP00000433421 | KH_2 | PF07650 | 3.9e-09 | 1 |
ENSP00000433421 | Ribosomal_S3_C | PF00189 | 5.5e-23 | 2 |
ENSP00000435457 | KH_2 | PF07650 | 1.1e-08 | 1 |
ENSP00000436556 | Ribosomal_S3_C | PF00189 | 3e-20 | 1 |
ENSP00000416745 | Ribosomal_S3_C | PF00189 | 6.2e-17 | 1 |
ENSP00000435566 | Ribosomal_S3_C | PF00189 | 2e-08 | 1 |
RNA binding proteomes (RBPomes)
Pubmed ID | Full Name | Cell | Author | Time | Doi |
---|
Literatures on RNA binding capacity
Pubmed ID | Title | Author | Time | Journal |
---|
Transcripts
Name | Transcript ID | bp | Protein | Translation ID |
---|---|---|---|---|
RPS3-212 | ENST00000529173 | 1373 | No protein | - |
RPS3-210 | ENST00000528439 | 473 | 91aa | ENSP00000432542 |
RPS3-217 | ENST00000531188 | 2059 | 243aa | ENSP00000434643 |
RPS3-214 | ENST00000530164 | 1878 | 117aa | ENSP00000433155 |
RPS3-216 | ENST00000530721 | 796 | 44aa | ENSP00000432458 |
RPS3-202 | ENST00000422465 | 903 | 103aa | ENSP00000416745 |
RPS3-201 | ENST00000278572 | 907 | 259aa | ENSP00000278572 |
RPS3-218 | ENST00000532872 | 737 | 115aa | ENSP00000431834 |
RPS3-219 | ENST00000534440 | 564 | 158aa | ENSP00000436335 |
RPS3-209 | ENST00000527446 | 1306 | 243aa | ENSP00000436971 |
RPS3-207 | ENST00000526608 | 710 | 231aa | ENSP00000433421 |
RPS3-208 | ENST00000527273 | 390 | 128aa | ENSP00000435457 |
RPS3-203 | ENST00000524851 | 866 | 243aa | ENSP00000433821 |
RPS3-206 | ENST00000526248 | 771 | 135aa | ENSP00000431737 |
RPS3-213 | ENST00000529285 | 550 | No protein | - |
RPS3-220 | ENST00000534555 | 387 | No protein | - |
RPS3-211 | ENST00000528847 | 639 | 36aa | ENSP00000435566 |
RPS3-205 | ENST00000525933 | 1307 | 171aa | ENSP00000436556 |
RPS3-204 | ENST00000525690 | 421 | 33aa | ENSP00000436476 |
RPS3-215 | ENST00000530170 | 531 | 123aa | ENSP00000437105 |
Phenotypes
ensgID | Trait | pValue | Pubmed ID |
---|
GWAS
ensgID | SNP | Chromosome | Position | Trait | PubmedID | Or or BEAT | EFO ID |
---|
Protein-Protein Interaction (PPI)
Paralogs
Ensembl ID | Source | Target | ||||||
---|---|---|---|---|---|---|---|---|
Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
ENSG00000149273 | homo_sapiens | ENSP00000496813 | 38.5057 | 24.1379 | homo_sapiens | ENSP00000434643 | 27.572 | 17.284 |
Orthologs
Ensembl ID | Source | Target | ||||||
---|---|---|---|---|---|---|---|---|
Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | pan_paniscus | ENSPPAP00000012063 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 97.9424 | 97.1193 | pongo_abelii | ENSPPYP00000004215 | 90.8397 | 90.0763 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | pan_troglodytes | ENSPTRP00000062955 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | gorilla_gorilla | ENSGGOP00000006379 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 98.7654 | 98.3539 | notamacropus_eugenii | ENSMEUP00000010558 | 98.7654 | 98.3539 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 83.9506 | 81.07 | choloepus_hoffmanni | ENSCHOP00000004720 | 93.1507 | 89.9543 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | dasypus_novemcinctus | ENSDNOP00000011538 | 91.3534 | 90.9774 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 98.3539 | 97.5309 | erinaceus_europaeus | ENSEEUP00000013268 | 98.3539 | 97.5309 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 82.716 | 82.716 | echinops_telfairi | ENSETEP00000012566 | 82.716 | 82.716 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 99.5885 | 99.5885 | callithrix_jacchus | ENSCJAP00000028461 | 85.8156 | 85.8156 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | cercocebus_atys | ENSCATP00000023620 | 90.6716 | 90.6716 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 29.6296 | 29.6296 | macaca_fascicularis | ENSMFAP00000039612 | 93.5065 | 93.5065 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | macaca_mulatta | ENSMMUP00000036826 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 63.786 | 62.5514 | macaca_nemestrina | ENSMNEP00000040701 | 94.5122 | 92.6829 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 78.6008 | 76.5432 | macaca_nemestrina | ENSMNEP00000013168 | 84.8889 | 82.6667 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | papio_anubis | ENSPANP00000000733 | 93.8224 | 93.8224 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | mandrillus_leucophaeus | ENSMLEP00000006717 | 93.8224 | 93.8224 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | tursiops_truncatus | ENSTTRP00000005538 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | vulpes_vulpes | ENSVVUP00000033702 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | mus_spretus | MGP_SPRETEiJ_P0084207 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | equus_asinus | ENSEASP00005020725 | 86.4769 | 86.121 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | capra_hircus | ENSCHIP00000009520 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | loxodonta_africana | ENSLAFP00000003582 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | panthera_leo | ENSPLOP00000008668 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | bos_indicus_hybrid | ENSBIXP00005045434 | 86.4769 | 86.4769 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | oryctolagus_cuniculus | ENSOCUP00000018598 | 86.4769 | 86.121 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | equus_caballus | ENSECAP00000011789 | 86.4769 | 86.121 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | canis_lupus_familiaris | ENSCAFP00845016559 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | panthera_pardus | ENSPPRP00000028833 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | marmota_marmota_marmota | ENSMMMP00000011026 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | balaenoptera_musculus | ENSBMSP00010009113 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | cavia_porcellus | ENSCPOP00000028766 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | felis_catus | ENSFCAP00000011080 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | ursus_americanus | ENSUAMP00000027871 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 99.5885 | 99.177 | monodelphis_domestica | ENSMODP00000008611 | 99.5885 | 99.177 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | bison_bison_bison | ENSBBBP00000026767 | 94.186 | 94.186 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | monodon_monoceros | ENSMMNP00015027057 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | sus_scrofa | ENSSSCP00000015774 | 92.7481 | 92.7481 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | microcebus_murinus | ENSMICP00000020936 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 89.3004 | 88.0658 | octodon_degus | ENSODEP00000003298 | 95.5947 | 94.2731 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 57.2016 | 53.4979 | octodon_degus | ENSODEP00000002300 | 90.2597 | 84.4156 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 89.3004 | 87.6543 | octodon_degus | ENSODEP00000000781 | 95.1754 | 93.4211 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 80.6584 | 75.3086 | octodon_degus | ENSODEP00000001653 | 87.8924 | 82.0628 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 44.0329 | 41.5638 | octodon_degus | ENSODEP00000004932 | 89.1667 | 84.1667 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 65.8436 | 64.6091 | octodon_degus | ENSODEP00000009109 | 99.3789 | 97.5155 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | jaculus_jaculus | ENSJJAP00000017418 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | ovis_aries_rambouillet | ENSOARP00020006090 | 93.4615 | 93.4615 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 73.251 | 72.8395 | ochotona_princeps | ENSOPRP00000008678 | 73.251 | 72.8395 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | delphinapterus_leucas | ENSDLEP00000003876 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | physeter_catodon | ENSPCTP00005017935 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | mus_caroli | MGP_CAROLIEiJ_P0080837 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | mus_musculus | ENSMUSP00000032998 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | dipodomys_ordii | ENSDORP00000002794 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | mustela_putorius_furo | ENSMPUP00000009120 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | aotus_nancymaae | ENSANAP00000019862 | 93.8224 | 93.8224 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | saimiri_boliviensis_boliviensis | ENSSBOP00000010077 | 93.8224 | 93.8224 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | vicugna_pacos | ENSVPAP00000010808 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | chlorocebus_sabaeus | ENSCSAP00000000282 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | tupaia_belangeri | ENSTBEP00000006091 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 94.2387 | 93.0041 | mesocricetus_auratus | ENSMAUP00000004722 | 98.7069 | 97.4138 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | phocoena_sinus | ENSPSNP00000008404 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 94.2387 | 92.5926 | carlito_syrichta | ENSTSYP00000018615 | 84.8148 | 83.3333 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | panthera_tigris_altaica | ENSPTIP00000012853 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 97.5309 | 95.8848 | rattus_norvegicus | ENSRNOP00000009988 | 97.5309 | 95.8848 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 61.7284 | 61.7284 | prolemur_simus | ENSPSMP00000026649 | 99.3377 | 99.3377 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | prolemur_simus | ENSPSMP00000003736 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | microtus_ochrogaster | ENSMOCP00000007818 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 95.0617 | 94.6502 | sorex_araneus | ENSSARP00000006343 | 95.8506 | 95.4357 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | peromyscus_maniculatus_bairdii | ENSPEMP00000025262 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | bos_mutus | ENSBMUP00000004815 | 94.186 | 94.186 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | mus_spicilegus | ENSMSIP00000032663 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 76.9547 | 73.6626 | cricetulus_griseus_chok1gshd | ENSCGRP00001003156 | 90.7767 | 86.8932 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | cricetulus_griseus_chok1gshd | ENSCGRP00001012207 | 86.4769 | 86.121 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 94.2387 | 93.8272 | pteropus_vampyrus | ENSPVAP00000010626 | 94.6281 | 94.2149 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 99.5885 | 99.177 | myotis_lucifugus | ENSMLUP00000003714 | 99.5885 | 99.177 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 60.0823 | 56.7901 | vombatus_ursinus | ENSVURP00010007928 | 90.6832 | 85.7143 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 59.2593 | 57.2016 | vombatus_ursinus | ENSVURP00010003617 | 96.6443 | 93.2886 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 98.7654 | 98.3539 | vombatus_ursinus | ENSVURP00010022232 | 98.7654 | 98.3539 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | rhinolophus_ferrumequinum | ENSRFEP00010027399 | 86.4769 | 86.121 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | neovison_vison | ENSNVIP00000029223 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | bos_taurus | ENSBTAP00000003962 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 99.5885 | 99.177 | heterocephalus_glaber_female | ENSHGLP00000027191 | 99.5885 | 99.177 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | rhinopithecus_bieti | ENSRBIP00000043513 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | canis_lupus_dingo | ENSCAFP00020002483 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 66.2551 | 65.8436 | sciurus_vulgaris | ENSSVLP00005020573 | 100 | 99.3789 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | sciurus_vulgaris | ENSSVLP00005028030 | 94.186 | 93.7984 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 56.3786 | 53.0864 | phascolarctos_cinereus | ENSPCIP00000025254 | 80.5882 | 75.8824 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 98.7654 | 98.3539 | phascolarctos_cinereus | ENSPCIP00000032530 | 98.7654 | 98.3539 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 30.8642 | 28.8066 | phascolarctos_cinereus | ENSPCIP00000051280 | 89.2857 | 83.3333 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 60.0823 | 57.2016 | phascolarctos_cinereus | ENSPCIP00000030287 | 96.6887 | 92.053 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 81.893 | 81.07 | procavia_capensis | ENSPCAP00000002830 | 81.893 | 81.07 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | nannospalax_galili | ENSNGAP00000014114 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | bos_grunniens | ENSBGRP00000037211 | 86.4769 | 86.4769 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | chinchilla_lanigera | ENSCLAP00000020172 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | cervus_hanglu_yarkandensis | ENSCHYP00000007057 | 62.6289 | 62.6289 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | catagonus_wagneri | ENSCWAP00000002419 | 92.7481 | 92.7481 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | otolemur_garnettii | ENSOGAP00000004758 | 99.5902 | 99.5902 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | cebus_imitator | ENSCCAP00000008838 | 90 | 90 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 99.5885 | 99.177 | urocitellus_parryii | ENSUPAP00010016925 | 99.5885 | 99.177 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | moschus_moschiferus | ENSMMSP00000013766 | 94.186 | 94.186 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | rhinopithecus_roxellana | ENSRROP00000002484 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 99.5885 | mus_pahari | MGP_PahariEiJ_P0017676 | 100 | 99.5885 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 100 | 100 | propithecus_coquereli | ENSPCOP00000031940 | 100 | 100 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 85.1852 | 74.4856 | caenorhabditis_elegans | C23G10.3.1 | 83.8057 | 73.2794 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 87.6543 | 80.2469 | drosophila_melanogaster | FBpp0312066 | 86.5854 | 79.2683 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 88.4774 | 85.5967 | ciona_intestinalis | ENSCINP00000010313 | 81.749 | 79.0875 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 78.6008 | 74.0741 | petromyzon_marinus | ENSPMAP00000008596 | 95.5 | 90 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 59.2593 | 53.0864 | eptatretus_burgeri | ENSEBUP00000005415 | 79.558 | 71.2707 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 98.3539 | 97.5309 | callorhinchus_milii | ENSCMIP00000043843 | 95.6 | 94.8 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 98.3539 | 95.4733 | fundulus_heteroclitus | ENSFHEP00000034432 | 97.551 | 94.6939 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 98.3539 | 97.5309 | notechis_scutatus | ENSNSUP00000023821 | 98.3539 | 97.5309 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 98.3539 | 97.5309 | pseudonaja_textilis | ENSPTXP00000021463 | 98.3539 | 97.5309 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 86.8313 | 84.3621 | naja_naja | ENSNNAP00000012024 | 84.4 | 82 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 88.4774 | 84.7737 | ciona_savignyi | ENSCSAVP00000005843 | 83.6576 | 80.1556 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 77.7778 | 65.8436 | saccharomyces_cerevisiae | YNL178W | 78.75 | 66.6667 |
ENSG00000149273 | homo_sapiens | ENSP00000434643 | 97.9424 | 97.1193 | nothobranchius_furzeri | ENSNFUP00015032038 | 94.4444 | 93.6508 |
Gene Ontology
Go ID | Go term | No. evidence | Entries | Species | Category |
---|---|---|---|---|---|
GO:0000977 | contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding | 1 | IMP | Homo_sapiens(9606) | Function |
GO:0002181 | involved_in cytoplasmic translation | 2 | IC,NAS | Homo_sapiens(9606) | Process |
GO:0003677 | enables DNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0003684 | enables damaged DNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0003723 | enables RNA binding | 2 | HDA,IDA | Homo_sapiens(9606) | Function |
GO:0003729 | enables mRNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0003735 | enables structural constituent of ribosome | 4 | HDA,IBA,IDA,NAS | Homo_sapiens(9606) | Function |
GO:0003906 | enables DNA-(apurinic or apyrimidinic site) endonuclease activity | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0004520 | enables DNA endonuclease activity | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0005515 | enables protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0005634 | is_active_in nucleus | 3 | IBA,IDA,IMP | Homo_sapiens(9606) | Component |
GO:0005654 | located_in nucleoplasm | 1 | TAS | Homo_sapiens(9606) | Component |
GO:0005730 | located_in nucleolus | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0005737 | located_in cytoplasm | 3 | IDA,IMP,NAS | Homo_sapiens(9606) | Component |
GO:0005743 | located_in mitochondrial inner membrane | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0005759 | located_in mitochondrial matrix | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0005783 | located_in endoplasmic reticulum | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0005829 | located_in cytosol | 2 | IDA,TAS | Homo_sapiens(9606) | Component |
GO:0005840 | located_in ribosome | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0005844 | part_of polysome | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0005886 | located_in plasma membrane | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0005925 | located_in focal adhesion | 1 | HDA | Homo_sapiens(9606) | Component |
GO:0006281 | involved_in DNA repair | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0006284 | involved_in base-excision repair | 1 | IDA | Homo_sapiens(9606) | Process |
GO:0006412 | involved_in translation | 2 | IC,NAS | Homo_sapiens(9606) | Process |
GO:0006413 | involved_in translational initiation | 1 | NAS | Homo_sapiens(9606) | Process |
GO:0006915 | involved_in apoptotic process | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0006974 | involved_in DNA damage response | 1 | IEP | Homo_sapiens(9606) | Process |
GO:0007059 | involved_in chromosome segregation | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0008017 | enables microtubule binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0010628 | involved_in positive regulation of gene expression | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0014069 | is_active_in postsynaptic density | 2 | EXP,IDA | Homo_sapiens(9606) | Component |
GO:0015631 | enables tubulin binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0016020 | located_in membrane | 1 | HDA | Homo_sapiens(9606) | Component |
GO:0017148 | involved_in negative regulation of translation | 1 | IDA | Homo_sapiens(9606) | Process |
GO:0019104 | NOT enables DNA N-glycosylase activity | 2 | IDA,TAS | Homo_sapiens(9606) | Function |
GO:0019899 | enables enzyme binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0019900 | enables kinase binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0019901 | enables protein kinase binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0022626 | located_in cytosolic ribosome | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0022627 | part_of cytosolic small ribosomal subunit | 4 | HDA,IBA,IDA,NAS | Homo_sapiens(9606) | Component |
GO:0030544 | enables Hsp70 protein binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0031116 | involved_in positive regulation of microtubule polymerization | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0031334 | involved_in positive regulation of protein-containing complex assembly | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0031397 | involved_in negative regulation of protein ubiquitination | 1 | IDA | Homo_sapiens(9606) | Process |
GO:0032079 | involved_in positive regulation of endodeoxyribonuclease activity | 1 | IDA | Homo_sapiens(9606) | Process |
GO:0032357 | enables oxidized purine DNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0032358 | enables oxidized pyrimidine DNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0032587 | located_in ruffle membrane | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0032743 | involved_in positive regulation of interleukin-2 production | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0034614 | involved_in cellular response to reactive oxygen species | 1 | IDA | Homo_sapiens(9606) | Process |
GO:0042104 | involved_in positive regulation of activated T cell proliferation | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0042981 | involved_in regulation of apoptotic process | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0043507 | involved_in positive regulation of JUN kinase activity | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0044390 | enables ubiquitin-like protein conjugating enzyme binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0044877 | enables protein-containing complex binding | 1 | IMP | Homo_sapiens(9606) | Function |
GO:0045738 | involved_in negative regulation of DNA repair | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0045739 | involved_in positive regulation of DNA repair | 1 | IDA | Homo_sapiens(9606) | Process |
GO:0050862 | involved_in positive regulation of T cell receptor signaling pathway | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0051018 | enables protein kinase A binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0051092 | involved_in positive regulation of NF-kappaB transcription factor activity | 2 | IGI,IMP | Homo_sapiens(9606) | Process |
GO:0051225 | involved_in spindle assembly | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0051301 | involved_in cell division | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0051536 | enables iron-sulfur cluster binding | 1 | NAS | Homo_sapiens(9606) | Function |
GO:0051879 | enables Hsp90 protein binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0061481 | involved_in response to TNF agonist | 1 | IDA | Homo_sapiens(9606) | Process |
GO:0070062 | located_in extracellular exosome | 1 | HDA | Homo_sapiens(9606) | Component |
GO:0070181 | enables small ribosomal subunit rRNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0070301 | involved_in cellular response to hydrogen peroxide | 1 | IDA | Homo_sapiens(9606) | Process |
GO:0071159 | part_of NF-kappaB complex | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0071356 | involved_in cellular response to tumor necrosis factor | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0072686 | located_in mitotic spindle | 1 | IDA | Homo_sapiens(9606) | Component |
GO:0097100 | enables supercoiled DNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
GO:0140078 | enables class I DNA-(apurinic or apyrimidinic site) endonuclease activity | 1 | IEA | Homo_sapiens(9606) | Function |
GO:0140297 | enables DNA-binding transcription factor binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:1901224 | involved_in positive regulation of NIK/NF-kappaB signaling | 1 | IDA | Homo_sapiens(9606) | Process |
GO:1902231 | involved_in positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage | 1 | IMP | Homo_sapiens(9606) | Process |
GO:1905053 | involved_in positive regulation of base-excision repair | 1 | IDA | Homo_sapiens(9606) | Process |
GO:1990904 | part_of ribonucleoprotein complex | 1 | IDA | Homo_sapiens(9606) | Component |
GO:2001235 | involved_in positive regulation of apoptotic signaling pathway | 2 | IBA,IDA | Homo_sapiens(9606) | Process |
GO:2001272 | involved_in positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis | 1 | IMP | Homo_sapiens(9606) | Process |