Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000148584 Gene ID 29974 Accession 24086
Symbol A1CF Alias ACF;ASP;ACF64;ACF65;APOBEC1CF Full Name APOBEC1 complementation factor
Status Confidence Length 86267 bases Strand Minus strand
Position 10 : 50799409 - 50885675 RNA binding domain DND1_DSRM , RRM_1
Summary Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000363109 RRM_1 PF00076 7.7e-39 1
ENSP00000363109 RRM_1 PF00076 7.7e-39 2
ENSP00000363109 RRM_1 PF00076 7.7e-39 3
ENSP00000363109 DND1_DSRM PF14709 6.1e-24 4
ENSP00000363113 RRM_1 PF00076 7.7e-39 1
ENSP00000363113 RRM_1 PF00076 7.7e-39 2
ENSP00000363113 RRM_1 PF00076 7.7e-39 3
ENSP00000363113 DND1_DSRM PF14709 6.1e-24 4
ENSP00000397953 RRM_1 PF00076 7.7e-39 1
ENSP00000397953 RRM_1 PF00076 7.7e-39 2
ENSP00000397953 RRM_1 PF00076 7.7e-39 3
ENSP00000397953 DND1_DSRM PF14709 6.1e-24 4
ENSP00000363105 RRM_1 PF00076 8.2e-39 1
ENSP00000363105 RRM_1 PF00076 8.2e-39 2
ENSP00000363105 RRM_1 PF00076 8.2e-39 3
ENSP00000363105 DND1_DSRM PF14709 6.3e-24 4
ENSP00000363107 RRM_1 PF00076 8.8e-39 1
ENSP00000363107 RRM_1 PF00076 8.8e-39 2
ENSP00000363107 RRM_1 PF00076 8.8e-39 3
ENSP00000363107 DND1_DSRM PF14709 6e-24 4
ENSP00000378873 RRM_1 PF00076 8.8e-39 1
ENSP00000378873 RRM_1 PF00076 8.8e-39 2
ENSP00000378873 RRM_1 PF00076 8.8e-39 3
ENSP00000378873 DND1_DSRM PF14709 6e-24 4
ENSP00000378868 RRM_1 PF00076 9.3e-39 1
ENSP00000378868 RRM_1 PF00076 9.3e-39 2
ENSP00000378868 RRM_1 PF00076 9.3e-39 3
ENSP00000378868 DND1_DSRM PF14709 6.2e-24 4

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35813212 Trends in the Contribution of Genetic Susceptibility Loci to Hyperuricemia and Gout and Associated Novel Mechanisms. Jianan Zhao 2022-01-01 Frontiers in cell and developmental biology
34981048 The Roles of APOBEC-mediated RNA Editing in SARS-CoV-2 Mutations, Replication and Fitness. Kyumin Kim 2022-04-07 bioRxiv : the preprint server for biology
31186064 Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells. Yichen Song 2019-06-11 Journal of experimental & clinical cancer research : CR
27231908 EIYMNVPV Motif is Essential for A1CF Nucleus Localization and A1CF (-8aa) Promotes Proliferation of MDA-MB-231 Cells via Up-Regulation of IL-6. Li Zhou 2016-05-25 International journal of molecular sciences
27283515 The APOBEC Protein Family: United by Structure, Divergent in Function. D Jason Salter 2016-07-01 Trends in biochemical sciences
27869537 RNA binding to APOBEC deaminases; Not simply a substrate for C to U editing. C Harold Smith 2017-09-02 RNA biology
35441170 The Roles of APOBEC-mediated RNA Editing in SARS-CoV-2 Mutations, Replication and Fitness. Kyumin Kim 2022-04-12 Research square
36100631 The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness. Kyumin Kim 2022-09-13 Scientific reports
30309881 Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver. Valerie Blanc 2019-01-01 RNA (New York, N.Y.)
34002283 APOBEC1 complementation factor facilitates cell migration by promoting nucleus translocation of SMAD3 in renal cell carcinoma cells. Hua Xia 2021-05-01 In vitro cellular & developmental biology. Animal
32503341 From the Argonauts Mythological Sailors to the Argonautes RNA-Silencing Navigators: Their Emerging Roles in Human-Cell Pathologies. I Vasiliki Pantazopoulou 2020-06-03 International journal of molecular sciences
35948620 Genetically-biased fertilization in APOBEC1 complementation factor (A1cf) mutant mice. Naoki Hirose 2022-08-10 Scientific reports
24898756 Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer. Sakari Vanharanta 2014-06-04 eLife
33692367 easyCLIP analysis of RNA-protein interactions incorporating absolute quantification. F Douglas Porter 2021-03-10 Nature communications

Transcripts

Name Transcript ID bp Protein Translation ID
A1CF-203 ENST00000373997 9221 586aa ENSP00000363109
A1CF-204 ENST00000374001 9221 586aa ENSP00000363113
A1CF-207 ENST00000414883 2224 586aa ENSP00000397953
A1CF-201 ENST00000373993 2044 594aa ENSP00000363105
A1CF-202 ENST00000373995 2211 594aa ENSP00000363107
A1CF-206 ENST00000395495 2079 594aa ENSP00000378873
A1CF-205 ENST00000395489 2278 602aa ENSP00000378868
A1CF-209 ENST00000493415 926 No protein -
A1CF-208 ENST00000473480 813 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
23107Body Height6.4030000E-005-
36488Platelet Function Tests8.1800000E-006-
76762Uric Acid7E-1723263486
85201Thinness1E-625811787
85202Uric Acid1E-625811787
91957Narcolepsy5E-625986216
93140Creatinine1E-1226831199
93141Glomerular Filtration Rate1E-1226831199

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000148584homo_sapiensENSP0000029597161.551448.9039homo_sapiensENSP0000036310962.286749.4881
ENSG00000148584homo_sapiensENSP0000030413921.683713.0102homo_sapiensENSP0000036310914.50518.70307
ENSG00000148584homo_sapiensENSP000004174517.21654.02999homo_sapiensENSP0000036310913.13997.33788
ENSG00000148584homo_sapiensENSP0000047869132.551320.8211homo_sapiensENSP0000036310918.94212.116
ENSG00000148584homo_sapiensENSP0000044536650.141632.2946homo_sapiensENSP0000036310930.204819.4539
ENSG00000148584homo_sapiensENSP0000034182632.795719.086homo_sapiensENSP0000036310920.819112.116
ENSG00000148584homo_sapiensENSP0000035009036.87521.875homo_sapiensENSP0000036310920.136511.9454
ENSG00000148584homo_sapiensENSP0000049380537.187521.5625homo_sapiensENSP0000036310920.307211.7747
ENSG00000148584homo_sapiensENSP0000037630929.629618.5185homo_sapiensENSP0000036310919.112611.9454
ENSG00000148584homo_sapiensENSP0000028407331.402419.2073homo_sapiensENSP0000036310917.576810.7509
ENSG00000148584homo_sapiensENSP0000031047135.097519.4986homo_sapiensENSP0000036310921.501711.9454
ENSG00000148584homo_sapiensENSP0000030916634.065918.4066homo_sapiensENSP0000036310921.160411.4334
ENSG00000148584homo_sapiensENSP0000049824823.589713.3333homo_sapiensENSP0000036310915.69978.87372
ENSG00000148584homo_sapiensENSP0000035964524.040914.0665homo_sapiensENSP0000036310916.0419.38567
ENSG00000148584homo_sapiensENSP0000040137137.046619.9482homo_sapiensENSP0000036310924.402713.1399
ENSG00000148584homo_sapiensENSP0000025755227.900616.5746homo_sapiensENSP0000036310917.235510.2389
ENSG00000148584homo_sapiensENSP0000028172264.72851.2195homo_sapiensENSP0000036310958.873746.587
ENSG00000148584homo_sapiensENSP0000035295624.145812.9841homo_sapiensENSP0000036310918.08879.72696
ENSG00000148584homo_sapiensENSP0000036293635.191615.6794homo_sapiensENSP0000036310917.23557.67918
ENSG00000148584homo_sapiensENSP0000031319922.816912.3944homo_sapiensENSP0000036310913.82257.50853
ENSG00000148584homo_sapiensENSP0000025336324.71712.6415homo_sapiensENSP0000036310922.354911.4334
ENSG00000148584homo_sapiensENSP0000031604230.819716.7213homo_sapiensENSP0000036310916.0418.70307
ENSG00000148584homo_sapiensENSP0000031819516.19727.88732homo_sapiensENSP0000036310919.62469.55631
ENSG00000148584homo_sapiensENSP0000039490237.866720.2667homo_sapiensENSP0000036310924.232112.9693
ENSG00000148584homo_sapiensENSP0000035110828.915715.3614homo_sapiensENSP0000036310916.38238.70307
ENSG00000148584homo_sapiensENSP0000026174111.45836.45833homo_sapiensENSP0000036310918.771310.5802
ENSG00000148584homo_sapiensENSP0000023307815.23348.84521homo_sapiensENSP0000036310910.58026.14334
ENSG00000148584homo_sapiensENSP0000037212715.52429.07258homo_sapiensENSP0000036310913.13997.67918
ENSG00000148584homo_sapiensENSP0000037210515.52429.07258homo_sapiensENSP0000036310913.13997.67918
ENSG00000148584homo_sapiensENSP0000037248415.72589.27419homo_sapiensENSP0000036310913.31067.84983
ENSG00000148584homo_sapiensENSP0000037215415.52429.07258homo_sapiensENSP0000036310913.13997.67918
ENSG00000148584homo_sapiensENSP0000025083115.72589.27419homo_sapiensENSP0000036310913.31067.84983
ENSG00000148584homo_sapiensENSP0000030715515.72589.27419homo_sapiensENSP0000036310913.31067.84983
ENSG00000148584homo_sapiensENSP0000029547021.190511.9048homo_sapiensENSP0000036310915.18778.53242
ENSG00000148584homo_sapiensENSP0000046602524.242415.4882homo_sapiensENSP0000036310912.28677.84983
ENSG00000148584homo_sapiensENSP0000036595040.127422.9299homo_sapiensENSP0000036310910.75096.14334

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000148584homo_sapiensENSP0000036310999.317498.9761nomascus_leucogenysENSNLEP0000001463797.815197.479
ENSG00000148584homo_sapiensENSP0000036310996.757795.3925pan_paniscusENSPPAP0000000978894.18692.8571
ENSG00000148584homo_sapiensENSP0000036310999.317498.8055pongo_abeliiENSPPYP0000000328697.815197.3109
ENSG00000148584homo_sapiensENSP0000036310999.658799.4881pan_troglodytesENSPTRP0000000432498.316598.1481
ENSG00000148584homo_sapiensENSP0000036310996.757795.3925gorilla_gorillaENSGGOP0000004470194.18692.8571
ENSG00000148584homo_sapiensENSP0000036310993.344789.2491ornithorhynchus_anatinusENSOANP0000001171593.82589.7084
ENSG00000148584homo_sapiensENSP0000036310992.832889.7611sarcophilus_harrisiiENSSHAP0000000584191.736988.7015
ENSG00000148584homo_sapiensENSP0000036310988.225385.6655notamacropus_eugeniiENSMEUP000000145389491.2727
ENSG00000148584homo_sapiensENSP0000036310992.491590.4437choloepus_hoffmanniENSCHOP0000000804291.554189.527
ENSG00000148584homo_sapiensENSP0000036310996.245794.8805dasypus_novemcinctusENSDNOP0000000219294.949593.6027
ENSG00000148584homo_sapiensENSP0000036310965.52963.4812erinaceus_europaeusENSEEUP0000000001083.842881.2227
ENSG00000148584homo_sapiensENSP0000036310977.645175.0853echinops_telfairiENSETEP0000001015977.118674.5763
ENSG00000148584homo_sapiensENSP0000036310998.976198.6348callithrix_jacchusENSCJAP0000004656097.643197.3064
ENSG00000148584homo_sapiensENSP0000036310992.832890.6143cercocebus_atysENSCATP0000004221791.428689.2437
ENSG00000148584homo_sapiensENSP0000036310998.634898.1229macaca_fascicularisENSMFAP0000002215492.92692.4437
ENSG00000148584homo_sapiensENSP0000036310995.733894.0273macaca_mulattaENSMMUP0000000927493.591.8333
ENSG00000148584homo_sapiensENSP0000036310995.392593.686macaca_nemestrinaENSMNEP0000001469993.166791.5
ENSG00000148584homo_sapiensENSP0000036310995.563193.8567papio_anubisENSPANP0000003253193.333391.6667
ENSG00000148584homo_sapiensENSP0000036310992.832890.6143mandrillus_leucophaeusENSMLEP0000002612391.428689.2437
ENSG00000148584homo_sapiensENSP0000036310989.078586.3481tursiops_truncatusENSTTRP0000001251788.02785.3288
ENSG00000148584homo_sapiensENSP0000036310996.928395.2218vulpes_vulpesENSVVUP0000000325397.594595.8763
ENSG00000148584homo_sapiensENSP0000036310995.221892.8328mus_spretusMGP_SPRETEiJ_P005055994.097891.7369
ENSG00000148584homo_sapiensENSP0000036310997.440396.9283equus_asinusENSEASP0000501875095.644995.1424
ENSG00000148584homo_sapiensENSP0000036310997.09995.3925capra_hircusENSCHIP0000002246695.630293.9496
ENSG00000148584homo_sapiensENSP0000036310996.245793.3447loxodonta_africanaENSLAFP0000001957494.789991.9328
ENSG00000148584homo_sapiensENSP0000036310993.344789.5904panthera_leoENSPLOP0000003108291.471687.7926
ENSG00000148584homo_sapiensENSP0000036310996.928395.2218ailuropoda_melanoleucaENSAMEP0000000056895.945994.2568
ENSG00000148584homo_sapiensENSP0000036310996.928395.9044bos_indicus_hybridENSBIXP0000501880595.462294.4538
ENSG00000148584homo_sapiensENSP0000036310997.09995.2218oryctolagus_cuniculusENSOCUP0000000996995.469893.6242
ENSG00000148584homo_sapiensENSP0000036310997.269696.4164equus_caballusENSECAP0000000848295.477494.6399
ENSG00000148584homo_sapiensENSP0000036310996.928395.3925canis_lupus_familiarisENSCAFP0084503988396.271294.7458
ENSG00000148584homo_sapiensENSP0000036310993.344789.5904panthera_pardusENSPPRP0000002126691.471687.7926
ENSG00000148584homo_sapiensENSP0000036310998.634897.4403marmota_marmota_marmotaENSMMMP0000002117696.333395.1667
ENSG00000148584homo_sapiensENSP0000036310997.440396.0751balaenoptera_musculusENSBMSP0001003078995.966494.6218
ENSG00000148584homo_sapiensENSP0000036310997.440396.0751cavia_porcellusENSCPOP0000000880396.127994.7811
ENSG00000148584homo_sapiensENSP0000036310993.344789.2491felis_catusENSFCAP0000004014791.471687.4582
ENSG00000148584homo_sapiensENSP0000036310997.09995.2218ursus_americanusENSUAMP0000002583897.431595.5479
ENSG00000148584homo_sapiensENSP0000036310993.856790.1024monodelphis_domesticaENSMODP0000002057692.592688.8889
ENSG00000148584homo_sapiensENSP0000036310996.928395.9044bison_bison_bisonENSBBBP0000001531795.462294.4538
ENSG00000148584homo_sapiensENSP0000036310996.075194.7099monodon_monocerosENSMMNP0001501816087.831586.5835
ENSG00000148584homo_sapiensENSP0000036310996.928396.0751sus_scrofaENSSSCP0000003918995.462294.6218
ENSG00000148584homo_sapiensENSP0000036310993.174191.4676microcebus_murinusENSMICP0000000307791.304389.6321
ENSG00000148584homo_sapiensENSP0000036310920.136519.7952octodon_degusENSODEP0000001653696.721395.082
ENSG00000148584homo_sapiensENSP0000036310920.819120.6485jaculus_jaculusENSJJAP0000000704810099.1803
ENSG00000148584homo_sapiensENSP0000036310996.928395.5631ovis_aries_rambouilletENSOARP0002002925695.462294.1176
ENSG00000148584homo_sapiensENSP0000036310996.416494.5392ursus_maritimusENSUMAP0000001518295.762793.8983
ENSG00000148584homo_sapiensENSP0000036310978.668977.6451ochotona_princepsENSOPRP0000000974584.898783.7937
ENSG00000148584homo_sapiensENSP0000036310997.09995.7338delphinapterus_leucasENSDLEP0000001234295.630294.2857
ENSG00000148584homo_sapiensENSP0000036310992.662190.273physeter_catodonENSPCTP0000502622790.954888.6097
ENSG00000148584homo_sapiensENSP0000036310995.733893.3447mus_caroliMGP_CAROLIEiJ_P004856594.285791.9328
ENSG00000148584homo_sapiensENSP0000036310995.733893.3447mus_musculusENSMUSP0000007523594.285791.9328
ENSG00000148584homo_sapiensENSP0000036310920.648520.6485dipodomys_ordiiENSDORP0000002306499.180399.1803
ENSG00000148584homo_sapiensENSP0000036310993.003489.9317mustela_putorius_furoENSMPUP0000001686792.060889.0203
ENSG00000148584homo_sapiensENSP0000036310996.245794.3686aotus_nancymaaeENSANAP0000000397893.687791.8605
ENSG00000148584homo_sapiensENSP0000036310995.904494.198saimiri_boliviensis_boliviensisENSSBOP0000001019793.510891.8469
ENSG00000148584homo_sapiensENSP0000036310983.105880.5461vicugna_pacosENSVPAP0000000568581.848779.3277
ENSG00000148584homo_sapiensENSP0000036310998.634898.1229chlorocebus_sabaeusENSCSAP0000000330897.635197.1284
ENSG00000148584homo_sapiensENSP0000036310995.904493.686mesocricetus_auratusENSMAUP0000000539594.453892.2689
ENSG00000148584homo_sapiensENSP0000036310992.832890.273phocoena_sinusENSPSNP0000002733590.515888.02
ENSG00000148584homo_sapiensENSP0000036310993.856792.3208camelus_dromedariusENSCDRP0000501245093.856792.3208
ENSG00000148584homo_sapiensENSP0000036310993.515491.6382carlito_syrichtaENSTSYP0000000163392.255990.404
ENSG00000148584homo_sapiensENSP0000036310993.344789.7611panthera_tigris_altaicaENSPTIP0000002548191.471687.9599
ENSG00000148584homo_sapiensENSP0000036310995.563193.0034rattus_norvegicusENSRNOP0000006280294.276191.7508
ENSG00000148584homo_sapiensENSP0000036310998.293597.2696prolemur_simusENSPSMP0000000435496.482495.4774
ENSG00000148584homo_sapiensENSP0000036310995.733893.686microtus_ochrogasterENSMOCP0000002539894.285792.2689
ENSG00000148584homo_sapiensENSP0000036310983.447181.57sorex_araneusENSSARP0000000538483.732981.8493
ENSG00000148584homo_sapiensENSP0000036310996.416494.3686peromyscus_maniculatus_bairdiiENSPEMP0000001553194.95892.9412
ENSG00000148584homo_sapiensENSP0000036310996.928395.7338bos_mutusENSBMUP0000001202496.763295.5707
ENSG00000148584homo_sapiensENSP0000036310991.808988.9079mus_spicilegusENSMSIP0000003091893.079690.1384
ENSG00000148584homo_sapiensENSP0000036310996.245794.198cricetulus_griseus_chok1gshdENSCGRP0000101735094.789992.7731
ENSG00000148584homo_sapiensENSP0000036310996.245794.3686myotis_lucifugusENSMLUP0000001464094.949593.0976
ENSG00000148584homo_sapiensENSP0000036310993.515490.273vombatus_ursinusENSVURP0001000372392.724289.5093
ENSG00000148584homo_sapiensENSP0000036310996.58795.3925rhinolophus_ferrumequinumENSRFEP0001003034895.446994.2664
ENSG00000148584homo_sapiensENSP0000036310997.440395.7338neovison_visonENSNVIP0000003116396.452794.7635
ENSG00000148584homo_sapiensENSP0000036310996.928395.9044bos_taurusENSBTAP0000003308096.763295.7411
ENSG00000148584homo_sapiensENSP0000036310997.269695.3925heterocephalus_glaber_femaleENSHGLP0000001252595.798393.9496
ENSG00000148584homo_sapiensENSP0000036310991.808990.785rhinopithecus_bietiENSRBIP0000003881795.729594.6619
ENSG00000148584homo_sapiensENSP0000036310996.928395.3925canis_lupus_dingoENSCAFP0002003402696.271294.7458
ENSG00000148584homo_sapiensENSP0000036310998.805597.4403sciurus_vulgarisENSSVLP0000500642997.147795.8054
ENSG00000148584homo_sapiensENSP0000036310993.856790.6143phascolarctos_cinereusENSPCIP0000000266794.339691.0806
ENSG00000148584homo_sapiensENSP0000036310962.457360.0683procavia_capensisENSPCAP0000000605262.244959.8639
ENSG00000148584homo_sapiensENSP0000036310997.269694.8805nannospalax_galiliENSNGAP0000001361295.798393.4454
ENSG00000148584homo_sapiensENSP0000036310996.928395.7338bos_grunniensENSBGRP0000002887895.462294.2857
ENSG00000148584homo_sapiensENSP0000036310997.781696.0751chinchilla_lanigeraENSCLAP0000001512496.140994.4631
ENSG00000148584homo_sapiensENSP0000036310997.09996.0751cervus_hanglu_yarkandensisENSCHYP0000003983695.630294.6218
ENSG00000148584homo_sapiensENSP0000036310996.757795.7338catagonus_wagneriENSCWAP0000001437495.294194.2857
ENSG00000148584homo_sapiensENSP0000036310920.819120.6485ictidomys_tridecemlineatusENSSTOP0000000515910099.1803
ENSG00000148584homo_sapiensENSP0000036310996.757795.0512otolemur_garnettiiENSOGAP0000001154995.77794.0878
ENSG00000148584homo_sapiensENSP0000036310995.733894.0273cebus_imitatorENSCCAP0000000337393.656191.9866
ENSG00000148584homo_sapiensENSP0000036310998.464297.099urocitellus_parryiiENSUPAP0001001347996.974895.6302
ENSG00000148584homo_sapiensENSP0000036310996.928395.9044moschus_moschiferusENSMMSP0000001748195.462294.4538
ENSG00000148584homo_sapiensENSP0000036310998.634898.1229rhinopithecus_roxellanaENSRROP0000003587997.635197.1284
ENSG00000148584homo_sapiensENSP0000036310995.563192.4915mus_pahariMGP_PahariEiJ_P002152894.117691.0924
ENSG00000148584homo_sapiensENSP0000036310998.122996.9283propithecus_coquereliENSPCOP0000002404196.476595.302
ENSG00000148584homo_sapiensENSP0000036310987.542780.7167callorhinchus_miliiENSCMIP0000004673784.653578.0528
ENSG00000148584homo_sapiensENSP0000036310989.419882.5939latimeria_chalumnaeENSLACP0000000913289.879983.0189
ENSG00000148584homo_sapiensENSP0000036310988.907981.3993lepisosteus_oculatusENSLOCP0000000761087.858380.4384
ENSG00000148584homo_sapiensENSP0000036310987.88479.1809clupea_harengusENSCHAP0000001236885.406376.9486
ENSG00000148584homo_sapiensENSP0000036310987.542779.5222danio_rerioENSDARP0000012683587.542779.5222
ENSG00000148584homo_sapiensENSP0000036310986.860179.3515carassius_auratusENSCARP0000006352985.690278.2828
ENSG00000148584homo_sapiensENSP0000036310984.812375.5973carassius_auratusENSCARP0000005288982.421273.466
ENSG00000148584homo_sapiensENSP0000036310983.617775.9386astyanax_mexicanusENSAMXP0000001872383.904176.1986
ENSG00000148584homo_sapiensENSP0000036310982.252675.5973ictalurus_punctatusENSIPUP0000001526086.225479.2487
ENSG00000148584homo_sapiensENSP0000036310989.078579.3515esox_luciusENSELUP0000000171088.474678.8136
ENSG00000148584homo_sapiensENSP0000036310987.88480.0341electrophorus_electricusENSEEEP0000000494187.140479.357
ENSG00000148584homo_sapiensENSP0000036310984.129774.4027oncorhynchus_kisutchENSOKIP0000501323883.27773.6487
ENSG00000148584homo_sapiensENSP0000036310984.47174.5734oncorhynchus_kisutchENSOKIP0000505525481.147571.6393
ENSG00000148584homo_sapiensENSP0000036310986.177576.9625oncorhynchus_mykissENSOMYP0000003297984.731575.6711
ENSG00000148584homo_sapiensENSP0000036310983.447172.8669oncorhynchus_mykissENSOMYP0000002797781.636171.2855
ENSG00000148584homo_sapiensENSP0000036310985.665575.7679salmo_salarENSSSAP0000011195683.388773.7542
ENSG00000148584homo_sapiensENSP0000036310984.300374.5734salmo_salarENSSSAP0000008871380.983671.6393
ENSG00000148584homo_sapiensENSP0000036310982.764572.3549salmo_truttaENSSTUP0000004718780.165370.0826
ENSG00000148584homo_sapiensENSP0000036310960.238947.6109salmo_truttaENSSTUP0000006806457.212345.2188
ENSG00000148584homo_sapiensENSP0000036310981.5772.3549gadus_morhuaENSGMOP0000003627777.471668.7196
ENSG00000148584homo_sapiensENSP0000036310980.375472.5256fundulus_heteroclitusENSFHEP0000003287480.78972.8988
ENSG00000148584homo_sapiensENSP0000036310986.348177.9864poecilia_reticulataENSPREP0000002415682.410474.43
ENSG00000148584homo_sapiensENSP0000036310986.348178.4983xiphophorus_maculatusENSXMAP0000001675082.950875.4098
ENSG00000148584homo_sapiensENSP0000036310983.617774.4027oryzias_latipesENSORLP0000001672282.352973.2773
ENSG00000148584homo_sapiensENSP0000036310985.153676.7918cyclopterus_lumpusENSCLMP0000501890783.865575.6302
ENSG00000148584homo_sapiensENSP0000036310986.177578.157oreochromis_niloticusENSONIP0000004119379.778872.3539
ENSG00000148584homo_sapiensENSP0000036310986.518878.3276haplochromis_burtoniENSHBUP0000001972883.940475.9934
ENSG00000148584homo_sapiensENSP0000036310984.812376.6212astatotilapia_callipteraENSACLP0000002563884.957376.7521
ENSG00000148584homo_sapiensENSP0000036310985.836277.9864sparus_aurataENSSAUP0001004244481.260173.8288
ENSG00000148584homo_sapiensENSP0000036310986.689478.3276lates_calcariferENSLCAP0001005746882.467574.513
ENSG00000148584homo_sapiensENSP0000036310990.27382.7645xenopus_tropicalisENSXETP0000001448789.509382.0643
ENSG00000148584homo_sapiensENSP0000036310992.662188.0546chrysemys_picta_belliiENSCPBP0000003826392.033987.4576
ENSG00000148584homo_sapiensENSP0000036310987.201482.9352sphenodon_punctatusENSSPUP0000000875786.463682.2335
ENSG00000148584homo_sapiensENSP0000036310988.225383.7884crocodylus_porosusENSCPRP0000501410488.679284.2196
ENSG00000148584homo_sapiensENSP0000036310919.453918.6007laticauda_laticaudataENSLLTP0000001775593.442689.3443
ENSG00000148584homo_sapiensENSP0000036310976.450569.4539notechis_scutatusENSNSUP0000001130385.988578.119
ENSG00000148584homo_sapiensENSP0000036310984.982979.5222pseudonaja_textilisENSPTXP0000002184688.141682.4779
ENSG00000148584homo_sapiensENSP0000036310985.665580.0341anas_platyrhynchos_platyrhynchosENSAPLP0000000243186.402880.7229
ENSG00000148584homo_sapiensENSP0000036310991.979587.5427gallus_gallusENSGALP0001003352692.771188.296
ENSG00000148584homo_sapiensENSP0000036310984.982980.5461meleagris_gallopavoENSMGAP0000000097392.910488.0597
ENSG00000148584homo_sapiensENSP0000036310991.979587.372serinus_canariaENSSCAP0000000484392.611787.9725
ENSG00000148584homo_sapiensENSP0000036310991.126386.1775parus_majorENSPMJP0000002069791.910586.9191
ENSG00000148584homo_sapiensENSP0000036310989.761183.6177anolis_carolinensisENSACAP0000001506790.533684.3373
ENSG00000148584homo_sapiensENSP0000036310986.518878.6689neolamprologus_brichardiENSNBRP0000000215683.940476.3245
ENSG00000148584homo_sapiensENSP0000036310986.177580.8874podarcis_muralisENSPMRP0000000891485.448480.203
ENSG00000148584homo_sapiensENSP0000036310920.136519.4539geospiza_fortisENSGFOP0000001970796.721393.4426
ENSG00000148584homo_sapiensENSP0000036310991.979587.372taeniopygia_guttataENSTGUP0000000526392.771188.1239
ENSG00000148584homo_sapiensENSP0000036310986.689479.5222erpetoichthys_calabaricusENSECRP0000000395586.247979.1171
ENSG00000148584homo_sapiensENSP0000036310985.494978.3276kryptolebias_marmoratusENSKMAP0000000874381.463474.6341
ENSG00000148584homo_sapiensENSP0000036310990.955685.6655salvator_merianaeENSSMRP0000001649791.896686.5517
ENSG00000148584homo_sapiensENSP0000036310983.788474.744oryzias_javanicusENSOJAP0000003942981.969973.1219
ENSG00000148584homo_sapiensENSP0000036310986.689478.4983amphilophus_citrinellusENSACIP0000001105684.10676.1589
ENSG00000148584homo_sapiensENSP0000036310982.593974.0614dicentrarchus_labraxENSDLAP0000502441876.340768.4543
ENSG00000148584homo_sapiensENSP0000036310983.95975.9386amphiprion_perculaENSAPEP0000001341882.550374.6644
ENSG00000148584homo_sapiensENSP0000036310955.80250oryzias_sinensisENSOSIP0000001993885.826876.9029
ENSG00000148584homo_sapiensENSP0000036310992.150287.7133pelodiscus_sinensisENSPSIP0000001140292.783588.3162
ENSG00000148584homo_sapiensENSP0000036310920.307219.7952gopherus_evgoodeiENSGEVP0000501142497.54195.082
ENSG00000148584homo_sapiensENSP0000036310987.37283.2765chelonoidis_abingdoniiENSCABP0000001485091.103286.8327
ENSG00000148584homo_sapiensENSP0000036310984.47176.7918seriola_dumeriliENSSDUP0000001910983.614976.0135
ENSG00000148584homo_sapiensENSP0000036310980.887473.7201cottoperca_gobioENSCGOP0000002635182.14974.87
ENSG00000148584homo_sapiensENSP0000036310944.709941.2969cottoperca_gobioENSCGOP0000002636485.34278.8274
ENSG00000148584homo_sapiensENSP0000036310993.003489.4198struthio_camelus_australisENSSCUP0000000080593.803890.1893
ENSG00000148584homo_sapiensENSP0000036310988.054684.471anser_brachyrhynchusENSABRP0000002369990.367886.69
ENSG00000148584homo_sapiensENSP0000036310982.764575.0853gasterosteus_aculeatusENSGACP0000001353181.375873.8255
ENSG00000148584homo_sapiensENSP0000036310984.812376.2799cynoglossus_semilaevisENSCSEP0000000361380.944672.8013
ENSG00000148584homo_sapiensENSP0000036310986.518878.3276poecilia_formosaENSPFOP0000000666182.573374.7557
ENSG00000148584homo_sapiensENSP0000036310986.518878.157poecilia_formosaENSPFOP0000000742082.573374.5928
ENSG00000148584homo_sapiensENSP0000036310985.836277.4744myripristis_murdjanENSMMDP0000502895983.833375.6667
ENSG00000148584homo_sapiensENSP0000036310985.665577.6451sander_luciopercaENSSLUP0000000801982.160474.4681
ENSG00000148584homo_sapiensENSP0000036310987.88484.3003strigops_habroptilaENSSHBP0000502335690.03586.3636
ENSG00000148584homo_sapiensENSP0000036310984.129776.1092amphiprion_ocellarisENSAOCP0000001854883.843575.8503
ENSG00000148584homo_sapiensENSP0000036310986.177581.7406terrapene_carolina_triunguisENSTMTP0000003051393.173488.3764
ENSG00000148584homo_sapiensENSP0000036310982.593972.0136hucho_huchoENSHHUP0000008038780.666770.3333
ENSG00000148584homo_sapiensENSP0000036310984.812374.9147hucho_huchoENSHHUP0000003903481.475471.9672
ENSG00000148584homo_sapiensENSP0000036310962.969355.4608betta_splendensENSBSLP0000004417685.81475.5814
ENSG00000148584homo_sapiensENSP0000036310989.249181.7406pygocentrus_nattereriENSPNAP0000002318187.751780.3691
ENSG00000148584homo_sapiensENSP0000036310986.689479.3515anabas_testudineusENSATEP0000001969883.278776.2295
ENSG00000148584homo_sapiensENSP0000036310915.52913.9932anabas_testudineusENSATEP0000001962181.98273.8739
ENSG00000148584homo_sapiensENSP0000036310978.839670.6485seriola_lalandi_dorsalisENSSLDP0000000542780.628372.2513
ENSG00000148584homo_sapiensENSP0000036310986.006877.3038labrus_bergyltaENSLBEP0000002771481.685673.4198
ENSG00000148584homo_sapiensENSP0000036310986.518878.4983pundamilia_nyerereiENSPNYP0000002377682.843175.1634
ENSG00000148584homo_sapiensENSP0000036310985.494976.7918mastacembelus_armatusENSMAMP0000005552582.131173.7705
ENSG00000148584homo_sapiensENSP0000036310920.819118.43stegastes_partitusENSSPAP0000002260482.432472.973
ENSG00000148584homo_sapiensENSP0000036310984.300374.5734oncorhynchus_tshawytschaENSOTSP0000501318881.2571.875
ENSG00000148584homo_sapiensENSP0000036310981.05870.3072oncorhynchus_tshawytschaENSOTSP0000504167784.369473.1794
ENSG00000148584homo_sapiensENSP0000036310982.935274.9147acanthochromis_polyacanthusENSAPOP0000000642479.672171.9672
ENSG00000148584homo_sapiensENSP0000036310992.491587.7133aquila_chrysaetos_chrysaetosENSACCP0002000435593.287488.4682
ENSG00000148584homo_sapiensENSP0000036310986.006877.9864nothobranchius_furzeriENSNFUP0001501476982.218674.5514
ENSG00000148584homo_sapiensENSP0000036310986.518878.4983cyprinodon_variegatusENSCVAP0000000865184.219376.412
ENSG00000148584homo_sapiensENSP0000036310988.225380.2048denticeps_clupeoidesENSDCDP0000005471085.313577.5578
ENSG00000148584homo_sapiensENSP0000036310985.836277.4744larimichthys_croceaENSLCRP0000500327282.324174.3044
ENSG00000148584homo_sapiensENSP0000036310985.324275.7679takifugu_rubripesENSTRUP0000000457281.566172.4307
ENSG00000148584homo_sapiensENSP0000036310991.808986.6894ficedula_albicollisENSFALP0000001375892.59987.4355
ENSG00000148584homo_sapiensENSP0000036310980.887473.0375hippocampus_comesENSHCOP0000001433977.577770.0491
ENSG00000148584homo_sapiensENSP0000036310985.494976.7918cyprinus_carpio_carpioENSCCRP0000017138884.628476.0135
ENSG00000148584homo_sapiensENSP0000036310987.201479.3515cyprinus_carpio_carpioENSCCRP0000001341886.026978.2828
ENSG00000148584homo_sapiensENSP0000036310991.979587.7133coturnix_japonicaENSCJPP0000501562192.93188.6207
ENSG00000148584homo_sapiensENSP0000036310986.518878.157poecilia_latipinnaENSPLAP0000000105983.663475.5776
ENSG00000148584homo_sapiensENSP0000036310986.518878.157poecilia_latipinnaENSPLAP0000001923883.663475.5776
ENSG00000148584homo_sapiensENSP0000036310987.201479.1809sinocyclocheilus_grahamiENSSGRP0000008380087.201479.1809
ENSG00000148584homo_sapiensENSP0000036310932.593929.6928sinocyclocheilus_grahamiENSSGRP0000000346886.03678.3784
ENSG00000148584homo_sapiensENSP0000036310984.812376.4505maylandia_zebraENSMZEP0000501761584.523876.1905
ENSG00000148584homo_sapiensENSP0000036310984.300375.7679tetraodon_nigroviridisENSTNIP0000000617080.325272.1951
ENSG00000148584homo_sapiensENSP0000036310987.542779.6928paramormyrops_kingsleyaeENSPKIP0000001046485.929678.2245
ENSG00000148584homo_sapiensENSP0000036310987.713380.2048scleropages_formosusENSSFOP0001501836186.386678.9916
ENSG00000148584homo_sapiensENSP0000036310989.078581.9113leptobrachium_leishanenseENSLLEP0000001709088.324981.2183
ENSG00000148584homo_sapiensENSP0000036310983.95975.0853scophthalmus_maximusENSSMAP0000002169282.136973.4558
ENSG00000148584homo_sapiensENSP0000036310985.665576.1092oryzias_melastigmaENSOMEP0000001214983.250473.9635

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1TASHomo_sapiens(9606)Function
GO:0003725NOT enables double-stranded RNA binding1IDAHomo_sapiens(9606)Function
GO:0003727enables single-stranded RNA binding1IDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus3IBA,IC,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IEAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0007566involved_in embryo implantation1IEAHomo_sapiens(9606)Process
GO:0010609involved_in mRNA localization resulting in post-transcriptional regulation of gene expression1IEAHomo_sapiens(9606)Process
GO:0016554involved_in cytidine to uridine editing1IDAHomo_sapiens(9606)Process
GO:0016556involved_in mRNA modification1IDAHomo_sapiens(9606)Process
GO:0030895part_of apolipoprotein B mRNA editing enzyme complex1IDAHomo_sapiens(9606)Component
GO:0045293part_of mRNA editing complex1NASHomo_sapiens(9606)Component
GO:0050821involved_in protein stabilization1IDAHomo_sapiens(9606)Process
GO:0140767enables enzyme-substrate adaptor activity1IDAHomo_sapiens(9606)Function
GO:1901537involved_in positive regulation of DNA demethylation1NASHomo_sapiens(9606)Process
GO:2000623involved_in negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1IDAHomo_sapiens(9606)Process

Expression