RBP Type
Canonical_RBPs
Diseases
SARS-COV-OC43 Flaviviruses SARS-COV-2 Dengue Zika
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
Stress granucle P-body
BulkPerturb-seq
Ensembl ID ENSG00000143621 Gene ID
3608 Accession
6037
Symbol
ILF2
Alias
NF45;PRO3063
Full Name
interleukin enhancer binding factor 2
Status
Confidence
Length
9241 bases
Strand
Minus strand
Position
1 : 153661788 - 153671028
RNA binding domain
DZF
Summary
The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000482909
DZF
PF07528 6.8e-95
1
ENSP00000355011
DZF
PF07528 9.2e-95
1
ENSP00000357673
DZF
PF07528 2e-11
1
ENSP00000357670
DZF
PF07528 4.6e-06
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
36717549 Reciprocal regulation of LINC00941 and SOX2 promotes progression of esophageal squamous cell carcinoma.
Jun-Tao Lu
2023-01-30
Cell death & disease
22504300 Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing.
Frank Rigo
2012-04-15
Nature chemical biology
30091184 Unconventional RNA-binding proteins step into the virus-host battlefront.
Manuel Garcia-Moreno
2018-11-01
Wiley interdisciplinary reviews. RNA
37298108 LncRNA H19 Regulates Breast Cancer DNA Damage Response and Sensitivity to PARP Inhibitors via Binding to ILF2.
Junsong Zhao
2023-05-23
International journal of molecular sciences
33673561 High Throughput Proteomic Exploration of Hypothermic Preservation Reveals Active Processes within the Cell Associated with Cold Ischemia Kinetic.
Ophélie Pasini-Chabot
2021-02-27
International journal of molecular sciences
31212927 Cellular Interleukin Enhancer-Binding Factor 2, ILF2, Inhibits Japanese Encephalitis Virus Replication In Vitro.
Xiaofang Cui
2019-06-17
Viruses
32433965 Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.
C Emily Freund
2020-05-19
Cell reports
37047232 NUSAP1 Binds ILF2 to Modulate R-Loop Accumulation and DNA Damage in Prostate Cancer.
Chun-Lung Chiu
2023-03-26
International journal of molecular sciences
33445467 Gain/Amplification of Chromosome Arm 1q21 in Multiple Myeloma.
Ichiro Hanamura
2021-01-12
Cancers
31482640 Codon bias confers stability to human mRNAs.
Fabian Hia
2019-11-05
EMBO reports
35719395 Transposable Elements in Pluripotent Stem Cells and Human Disease.
Gang Ma
2022-01-01
Frontiers in genetics
30652130 Regulation of RNA editing by RNA-binding proteins in human cells.
Giovanni Quinones-Valdez
2019-01-01
Communications biology
35586566 ILF2 Contributes to Hyperproliferation of Keratinocytes and Skin Inflammation in a KLHDC7B-DT-Dependent Manner in Psoriasis.
Xiran Yin
2022-01-01
Frontiers in genetics
34696782 Hsa_circ_0004296 inhibits metastasis of prostate cancer by interacting with EIF4A3 to prevent nuclear export of ETS1 mRNA.
Shiyu Mao
2021-10-25
Journal of experimental & clinical cancer research : CR
33975879 Nicotine-Induced ILF2 Facilitates Nuclear mRNA Export of Pluripotency Factors to Promote Stemness and Chemoresistance in Human Esophageal Cancer.
Yue Li
2021-07-01
Cancer research
27556459 Expression and Critical Role of Interleukin Enhancer Binding Factor 2 in Hepatocellular Carcinoma.
Shaobing Cheng
2016-08-22
International journal of molecular sciences
Name
Transcript ID
bp
Protein
Translation ID
ILF2-201
ENST00000361891
1852
390aa
ENSP00000355011
ILF2-204
ENST00000480213
1008
No protein
-
ILF2-203
ENST00000368684
476
115aa
ENSP00000357673
ILF2-202
ENST00000368681
726
150aa
ENSP00000357670
ILF2-205
ENST00000615950
1906
352aa
ENSP00000482909
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
105071 Multiple Myeloma 4E-6 23502783 105732 Multiple Myeloma 9E-6 23502783
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000143621 homo_sapiens ENSP00000468181 15.3675 8.57461 homo_sapiens ENSP00000355011 35.3846 19.7436 ENSG00000143621 homo_sapiens ENSP00000457501 19.9203 8.76494 homo_sapiens ENSP00000355011 25.641 11.2821 ENSG00000143621 homo_sapiens ENSP00000265069 14.1527 7.63501 homo_sapiens ENSP00000355011 38.9744 21.0256 ENSG00000143621 homo_sapiens ENSP00000321347 20.6845 10.7143 homo_sapiens ENSP00000355011 35.641 18.4615 ENSG00000143621 homo_sapiens ENSP00000015877 16.4051 9.27247 homo_sapiens ENSP00000355011 29.4872 16.6667 ENSG00000143621 homo_sapiens ENSP00000262961 15.5485 8.94569 homo_sapiens ENSP00000355011 37.4359 21.5385 ENSG00000143621 homo_sapiens ENSP00000325153 18.0103 10.4631 homo_sapiens ENSP00000355011 26.9231 15.641 ENSG00000143621 homo_sapiens ENSP00000296513 18.4028 9.89583 homo_sapiens ENSP00000355011 27.1795 14.6154 ENSG00000143621 homo_sapiens ENSP00000360922 14.9047 7.27903 homo_sapiens ENSP00000355011 22.0513 10.7692 ENSG00000143621 homo_sapiens ENSP00000370713 15.5616 9.60758 homo_sapiens ENSP00000355011 29.4872 18.2051 ENSG00000143621 homo_sapiens ENSP00000318176 20.7668 9.90415 homo_sapiens ENSP00000355011 16.6667 7.94872 ENSG00000143621 homo_sapiens ENSP00000428756 15.9649 8.77193 homo_sapiens ENSP00000355011 23.3333 12.8205 ENSG00000143621 homo_sapiens ENSP00000357459 9.78793 5.38336 homo_sapiens ENSP00000355011 30.7692 16.9231 ENSG00000143621 homo_sapiens ENSP00000266987 22.9508 13.388 homo_sapiens ENSP00000355011 21.5385 12.5641
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000143621 homo_sapiens ENSP00000355011 98.9744 98.9744 nomascus_leucogenys ENSNLEP00000012829 99.7416 99.7416 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 pan_paniscus ENSPPAP00000000528 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 pongo_abelii ENSPPYP00000000934 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 pan_troglodytes ENSPTRP00000086351 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 91.7949 91.5385 pan_troglodytes ENSPTRP00000079288 98.0822 97.8082 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 gorilla_gorilla ENSGGOP00000001788 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 70.2564 64.359 ornithorhynchus_anatinus ENSOANP00000049029 55.1308 50.503 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 98.2051 sarcophilus_harrisii ENSSHAP00000011808 99.7436 98.2051 ENSG00000143621 homo_sapiens ENSP00000355011 99.2308 97.6923 notamacropus_eugenii ENSMEUP00000003340 99.7423 98.1959 ENSG00000143621 homo_sapiens ENSP00000355011 74.6154 74.359 choloepus_hoffmanni ENSCHOP00000002933 74.2347 73.9796 ENSG00000143621 homo_sapiens ENSP00000355011 77.4359 71.7949 dasypus_novemcinctus ENSDNOP00000019692 85.7955 79.5455 ENSG00000143621 homo_sapiens ENSP00000355011 97.4359 96.9231 dasypus_novemcinctus ENSDNOP00000011808 97.1867 96.6752 ENSG00000143621 homo_sapiens ENSP00000355011 83.8462 83.8462 erinaceus_europaeus ENSEEUP00000011951 83.8462 83.8462 ENSG00000143621 homo_sapiens ENSP00000355011 49.7436 49.2308 echinops_telfairi ENSETEP00000011220 66.2116 65.529 ENSG00000143621 homo_sapiens ENSP00000355011 99.2308 98.4615 callithrix_jacchus ENSCJAP00000077435 99.2308 98.4615 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 callithrix_jacchus ENSCJAP00000019098 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 cercocebus_atys ENSCATP00000045746 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.4872 99.4872 macaca_fascicularis ENSMFAP00000058215 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 59.2308 58.9744 macaca_fascicularis ENSMFAP00000014236 98.7179 98.2906 ENSG00000143621 homo_sapiens ENSP00000355011 99.4872 99.4872 macaca_mulatta ENSMMUP00000066528 94.4039 94.4039 ENSG00000143621 homo_sapiens ENSP00000355011 57.9487 57.1795 macaca_nemestrina ENSMNEP00000002581 98.2609 96.9565 ENSG00000143621 homo_sapiens ENSP00000355011 92.8205 92.8205 macaca_nemestrina ENSMNEP00000002407 95.0131 95.0131 ENSG00000143621 homo_sapiens ENSP00000355011 93.5897 92.8205 papio_anubis ENSPANP00000053955 97.8552 97.0509 ENSG00000143621 homo_sapiens ENSP00000355011 100 99.7436 papio_anubis ENSPANP00000052327 100 99.7436 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 papio_anubis ENSPANP00000011186 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 84.1026 84.1026 mandrillus_leucophaeus ENSMLEP00000027455 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 tursiops_truncatus ENSTTRP00000013994 99.4898 99.4898 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 vulpes_vulpes ENSVVUP00000039659 93.9759 93.9759 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 mus_spretus MGP_SPRETEiJ_P0061207 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.4872 99.4872 equus_asinus ENSEASP00005001033 95.3317 95.3317 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 capra_hircus ENSCHIP00000009045 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.7436 loxodonta_africana ENSLAFP00000025865 99.7436 99.7436 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 panthera_leo ENSPLOP00000013831 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 99.4872 ailuropoda_melanoleuca ENSAMEP00000012810 100 99.4872 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 bos_indicus_hybrid ENSBIXP00005002065 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.7436 oryctolagus_cuniculus ENSOCUP00000004714 95.5774 95.5774 ENSG00000143621 homo_sapiens ENSP00000355011 99.4872 99.4872 equus_caballus ENSECAP00000035579 95.3317 95.3317 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 canis_lupus_familiaris ENSCAFP00845002393 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 panthera_pardus ENSPPRP00000002037 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 marmota_marmota_marmota ENSMMMP00000020407 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 balaenoptera_musculus ENSBMSP00010026685 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.7436 cavia_porcellus ENSCPOP00000005263 99.7436 99.7436 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.7436 felis_catus ENSFCAP00000007571 61.9427 61.9427 ENSG00000143621 homo_sapiens ENSP00000355011 25.641 25.3846 ursus_americanus ENSUAMP00000004392 90.9091 90 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 93.3333 monodelphis_domestica ENSMODP00000048186 91.8519 89.8765 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 bison_bison_bison ENSBBBP00000019630 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 monodon_monoceros ENSMMNP00015002168 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.4872 sus_scrofa ENSSSCP00000030729 99.7436 99.4872 ENSG00000143621 homo_sapiens ENSP00000355011 60 60 microcebus_murinus ENSMICP00000012523 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 78.9744 76.1538 microcebus_murinus ENSMICP00000041449 94.7692 91.3846 ENSG00000143621 homo_sapiens ENSP00000355011 35.8974 35.641 octodon_degus ENSODEP00000015925 88.0503 87.4214 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.7436 jaculus_jaculus ENSJJAP00000023529 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 86.4103 83.5897 jaculus_jaculus ENSJJAP00000009718 93.8719 90.8078 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 ovis_aries_rambouillet ENSOARP00020001176 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 90.2564 90 ursus_maritimus ENSUMAP00000028472 100 99.7159 ENSG00000143621 homo_sapiens ENSP00000355011 65.8974 65.8974 ochotona_princeps ENSOPRP00000003418 99.6124 99.6124 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 94.8718 delphinapterus_leucas ENSDLEP00000013961 94.1476 94.1476 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 physeter_catodon ENSPCTP00005025937 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 mus_caroli MGP_CAROLIEiJ_P0058851 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 mus_musculus ENSMUSP00000001042 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 76.6667 74.8718 dipodomys_ordii ENSDORP00000019398 92.284 90.1235 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 dipodomys_ordii ENSDORP00000022495 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 98.7179 98.7179 mustela_putorius_furo ENSMPUP00000008205 96.01 96.01 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 aotus_nancymaae ENSANAP00000000903 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 83.3333 81.7949 aotus_nancymaae ENSANAP00000042397 94.2029 92.4638 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 saimiri_boliviensis_boliviensis ENSSBOP00000033748 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 85.8974 84.6154 saimiri_boliviensis_boliviensis ENSSBOP00000012824 95.7143 94.2857 ENSG00000143621 homo_sapiens ENSP00000355011 99.4872 99.4872 vicugna_pacos ENSVPAP00000009546 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.7436 chlorocebus_sabaeus ENSCSAP00000016165 99.7436 99.7436 ENSG00000143621 homo_sapiens ENSP00000355011 98.9744 98.7179 chlorocebus_sabaeus ENSCSAP00000018515 98.9744 98.7179 ENSG00000143621 homo_sapiens ENSP00000355011 79.4872 79.4872 tupaia_belangeri ENSTBEP00000012935 84.4687 84.4687 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 mesocricetus_auratus ENSMAUP00000013993 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 phocoena_sinus ENSPSNP00000001980 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 camelus_dromedarius ENSCDRP00005024494 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 carlito_syrichta ENSTSYP00000011068 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 79.2308 78.4615 carlito_syrichta ENSTSYP00000017877 93.3535 92.4471 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 panthera_tigris_altaica ENSPTIP00000020278 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 82.8205 81.2821 rattus_norvegicus ENSRNOP00000045539 67.7149 66.457 ENSG00000143621 homo_sapiens ENSP00000355011 45.8974 43.8462 prolemur_simus ENSPSMP00000001246 94.2105 90 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 prolemur_simus ENSPSMP00000030115 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.4872 99.4872 microtus_ochrogaster ENSMOCP00000017556 99.2327 99.2327 ENSG00000143621 homo_sapiens ENSP00000355011 66.1538 66.1538 sorex_araneus ENSSARP00000010828 66.6667 66.6667 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 peromyscus_maniculatus_bairdii ENSPEMP00000019550 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 bos_mutus ENSBMUP00000036079 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 mus_spicilegus ENSMSIP00000001076 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 88.7179 86.4103 cricetulus_griseus_chok1gshd ENSCGRP00001010319 95.8449 93.3518 ENSG00000143621 homo_sapiens ENSP00000355011 99.4872 99.4872 cricetulus_griseus_chok1gshd ENSCGRP00001007185 99.2327 99.2327 ENSG00000143621 homo_sapiens ENSP00000355011 99.4872 99.2308 pteropus_vampyrus ENSPVAP00000010442 98.9796 98.7245 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.2308 myotis_lucifugus ENSMLUP00000001679 99.7436 99.2308 ENSG00000143621 homo_sapiens ENSP00000355011 97.6923 96.9231 myotis_lucifugus ENSMLUP00000017208 97.6923 96.9231 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 98.2051 vombatus_ursinus ENSVURP00010022301 99.7436 98.2051 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 98.2051 vombatus_ursinus ENSVURP00010029567 99.7436 98.2051 ENSG00000143621 homo_sapiens ENSP00000355011 100 99.7436 rhinolophus_ferrumequinum ENSRFEP00010022947 100 99.7436 ENSG00000143621 homo_sapiens ENSP00000355011 94.1026 94.1026 neovison_vison ENSNVIP00000019379 99.7283 99.7283 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 bos_taurus ENSBTAP00000016549 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 82.5641 79.4872 heterocephalus_glaber_female ENSHGLP00000034980 73.1818 70.4545 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 heterocephalus_glaber_female ENSHGLP00000005655 92.6366 92.6366 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 rhinopithecus_bieti ENSRBIP00000038195 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 96.4103 96.1538 canis_lupus_dingo ENSCAFP00020012803 96.6581 96.401 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 sciurus_vulgaris ENSSVLP00005013041 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 98.2051 phascolarctos_cinereus ENSPCIP00000040111 99.7436 98.2051 ENSG00000143621 homo_sapiens ENSP00000355011 43.3333 43.3333 procavia_capensis ENSPCAP00000015319 76.8182 76.8182 ENSG00000143621 homo_sapiens ENSP00000355011 100 99.4872 nannospalax_galili ENSNGAP00000009483 100 99.4872 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 bos_grunniens ENSBGRP00000010648 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 chinchilla_lanigera ENSCLAP00000004417 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 cervus_hanglu_yarkandensis ENSCHYP00000025877 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 99.7436 99.7436 catagonus_wagneri ENSCWAP00000003348 99.7436 99.7436 ENSG00000143621 homo_sapiens ENSP00000355011 76.1538 74.6154 ictidomys_tridecemlineatus ENSSTOP00000030375 88.3929 86.6071 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 ictidomys_tridecemlineatus ENSSTOP00000000598 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 96.6667 96.4103 ictidomys_tridecemlineatus ENSSTOP00000017202 97.416 97.1576 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 cebus_imitator ENSCCAP00000007373 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 urocitellus_parryii ENSUPAP00010019552 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 moschus_moschiferus ENSMMSP00000017892 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 92.3077 92.3077 rhinopithecus_roxellana ENSRROP00000015632 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 100 100 mus_pahari MGP_PahariEiJ_P0069808 100 100 ENSG00000143621 homo_sapiens ENSP00000355011 47.6923 43.0769 propithecus_coquereli ENSPCOP00000011419 90.2913 81.5534 ENSG00000143621 homo_sapiens ENSP00000355011 50.2564 35.641 caenorhabditis_elegans R11H6.5.1 50.1279 35.5499 ENSG00000143621 homo_sapiens ENSP00000355011 74.6154 57.6923 drosophila_melanogaster FBpp0082066 73.4848 56.8182 ENSG00000143621 homo_sapiens ENSP00000355011 73.5897 57.1795 ciona_intestinalis ENSCINP00000029733 78.2016 60.7629 ENSG00000143621 homo_sapiens ENSP00000355011 64.8718 52.5641 eptatretus_burgeri ENSEBUP00000018824 78.3282 63.4675 ENSG00000143621 homo_sapiens ENSP00000355011 85.8974 81.7949 latimeria_chalumnae ENSLACP00000008343 94.3662 89.8592 ENSG00000143621 homo_sapiens ENSP00000355011 53.8462 51.7949 lepisosteus_oculatus ENSLOCP00000008324 96.3303 92.6606 ENSG00000143621 homo_sapiens ENSP00000355011 94.359 88.7179 danio_rerio ENSDARP00000022486 95.0904 89.4057 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 89.4872 carassius_auratus ENSCARP00000062841 72.8346 68.7008 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.4872 carassius_auratus ENSCARP00000131096 94.3734 89.2583 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.4872 carassius_auratus ENSCARP00000115288 70.8253 66.9866 ENSG00000143621 homo_sapiens ENSP00000355011 95.641 90.2564 astyanax_mexicanus ENSAMXP00000011211 96.3824 90.9561 ENSG00000143621 homo_sapiens ENSP00000355011 88.2051 81.7949 ictalurus_punctatus ENSIPUP00000032655 86.8687 80.5556 ENSG00000143621 homo_sapiens ENSP00000355011 80 69.2308 esox_lucius ENSELUP00000077500 77.2277 66.8317 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 89.4872 esox_lucius ENSELUP00000016125 94.1476 88.8041 ENSG00000143621 homo_sapiens ENSP00000355011 95.641 90 electrophorus_electricus ENSEEEP00000032774 96.3824 90.6977 ENSG00000143621 homo_sapiens ENSP00000355011 84.6154 72.3077 oncorhynchus_kisutch ENSOKIP00005035041 83.5443 71.3924 ENSG00000143621 homo_sapiens ENSP00000355011 64.359 52.0513 oncorhynchus_kisutch ENSOKIP00005034802 37.1302 30.0296 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.2308 oncorhynchus_kisutch ENSOKIP00005042307 94.8586 89.4602 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.2308 oncorhynchus_kisutch ENSOKIP00005071289 95.3488 89.9225 ENSG00000143621 homo_sapiens ENSP00000355011 87.6923 75.3846 oncorhynchus_mykiss ENSOMYP00000001004 74.026 63.6364 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.4872 oncorhynchus_mykiss ENSOMYP00000044336 95.3488 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 60.7692 49.4872 oncorhynchus_mykiss ENSOMYP00000002091 78.4768 63.9073 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 89.7436 oncorhynchus_mykiss ENSOMYP00000021449 95.6072 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 61.5385 48.7179 salmo_salar ENSSSAP00000092525 80.8081 63.9731 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 89.4872 salmo_salar ENSSSAP00000061399 95.6072 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 87.6923 75.3846 salmo_salar ENSSSAP00000048176 68.2635 58.6826 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.2308 salmo_salar ENSSSAP00000092571 94.8586 89.4602 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.4872 salmo_trutta ENSSTUP00000090485 95.3488 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 87.4359 75.1282 salmo_trutta ENSSTUP00000087112 86.3291 74.1772 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 89.7436 salmo_trutta ENSSTUP00000035261 95.6072 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 51.5385 40.5128 salmo_trutta ENSSTUP00000033102 72.5632 57.0397 ENSG00000143621 homo_sapiens ENSP00000355011 94.1026 89.7436 gadus_morhua ENSGMOP00000055355 85.7477 81.7757 ENSG00000143621 homo_sapiens ENSP00000355011 41.2821 35.3846 fundulus_heteroclitus ENSFHEP00000005509 64.6586 55.4217 ENSG00000143621 homo_sapiens ENSP00000355011 28.7179 26.6667 fundulus_heteroclitus ENSFHEP00000004119 76.1905 70.7483 ENSG00000143621 homo_sapiens ENSP00000355011 85.641 81.2821 poecilia_reticulata ENSPREP00000029909 95.702 90.8309 ENSG00000143621 homo_sapiens ENSP00000355011 94.359 89.4872 xiphophorus_maculatus ENSXMAP00000003310 95.0904 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 95.1282 88.2051 oryzias_latipes ENSORLP00000013739 95.8656 88.8889 ENSG00000143621 homo_sapiens ENSP00000355011 95.641 89.7436 cyclopterus_lumpus ENSCLMP00005007307 95.8869 89.9743 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 89.7436 oreochromis_niloticus ENSONIP00000030400 96.124 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 89.7436 haplochromis_burtoni ENSHBUP00000006123 96.124 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 95.1282 89.4872 astatotilapia_calliptera ENSACLP00000025221 81.5385 76.7033 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 90 sparus_aurata ENSSAUP00010036526 96.124 90.6977 ENSG00000143621 homo_sapiens ENSP00000355011 81.5385 75.8974 lates_calcarifer ENSLCAP00010011019 88.0886 81.9945 ENSG00000143621 homo_sapiens ENSP00000355011 82.8205 75.8974 xenopus_tropicalis ENSXETP00000109034 79.3612 72.7273 ENSG00000143621 homo_sapiens ENSP00000355011 98.7179 97.1795 chrysemys_picta_bellii ENSCPBP00000036603 98.7179 97.1795 ENSG00000143621 homo_sapiens ENSP00000355011 58.9744 57.9487 sphenodon_punctatus ENSSPUP00000004971 97.8723 96.1702 ENSG00000143621 homo_sapiens ENSP00000355011 97.6923 95.8974 crocodylus_porosus ENSCPRP00005019465 90.9308 89.2601 ENSG00000143621 homo_sapiens ENSP00000355011 98.4615 95.3846 laticauda_laticaudata ENSLLTP00000001546 98.4615 95.3846 ENSG00000143621 homo_sapiens ENSP00000355011 88.7179 85.8974 notechis_scutatus ENSNSUP00000008128 98.2955 95.1705 ENSG00000143621 homo_sapiens ENSP00000355011 97.9487 94.8718 notechis_scutatus ENSNSUP00000006891 90.3073 87.4705 ENSG00000143621 homo_sapiens ENSP00000355011 97.9487 94.8718 notechis_scutatus ENSNSUP00000007747 90.3073 87.4705 ENSG00000143621 homo_sapiens ENSP00000355011 89.2308 85.3846 notechis_scutatus ENSNSUP00000008124 82.0755 78.5377 ENSG00000143621 homo_sapiens ENSP00000355011 88.9744 86.1538 pseudonaja_textilis ENSPTXP00000025044 98.5795 95.4545 ENSG00000143621 homo_sapiens ENSP00000355011 88.9744 86.1538 pseudonaja_textilis ENSPTXP00000025065 98.5795 95.4545 ENSG00000143621 homo_sapiens ENSP00000355011 88.9744 87.1795 anas_platyrhynchos_platyrhynchos ENSAPLP00000016059 98.5795 96.5909 ENSG00000143621 homo_sapiens ENSP00000355011 94.1026 92.0513 gallus_gallus ENSGALP00010042061 75.3593 73.7166 ENSG00000143621 homo_sapiens ENSP00000355011 97.1795 95.1282 meleagris_gallopavo ENSMGAP00000024110 98.6979 96.6146 ENSG00000143621 homo_sapiens ENSP00000355011 88.9744 87.4359 serinus_canaria ENSSCAP00000008952 98.5795 96.875 ENSG00000143621 homo_sapiens ENSP00000355011 89.2308 85.3846 parus_major ENSPMJP00000001629 59.0832 56.5365 ENSG00000143621 homo_sapiens ENSP00000355011 92.0513 86.6667 neolamprologus_brichardi ENSNBRP00000023696 90.201 84.9246 ENSG00000143621 homo_sapiens ENSP00000355011 98.4615 95.1282 naja_naja ENSNNAP00000017715 91.4286 88.3333 ENSG00000143621 homo_sapiens ENSP00000355011 97.9487 95.3846 podarcis_muralis ENSPMRP00000028362 97.9487 95.3846 ENSG00000143621 homo_sapiens ENSP00000355011 87.4359 85.641 geospiza_fortis ENSGFOP00000019821 96.3277 94.3503 ENSG00000143621 homo_sapiens ENSP00000355011 97.1795 95.3846 taeniopygia_guttata ENSTGUP00000025681 98.6979 96.875 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 91.2821 erpetoichthys_calabaricus ENSECRP00000012686 95.3846 91.2821 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 89.2308 kryptolebias_marmoratus ENSKMAP00000001025 95.6072 89.9225 ENSG00000143621 homo_sapiens ENSP00000355011 97.6923 95.1282 salvator_merianae ENSSMRP00000000664 97.6923 95.1282 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 88.4615 oryzias_javanicus ENSOJAP00000012116 96.124 89.1473 ENSG00000143621 homo_sapiens ENSP00000355011 86.1538 81.0256 amphilophus_citrinellus ENSACIP00000017293 96.2751 90.5444 ENSG00000143621 homo_sapiens ENSP00000355011 95.1282 89.7436 dicentrarchus_labrax ENSDLAP00005017955 95.8656 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 89.4872 amphiprion_percula ENSAPEP00000024003 96.124 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 88.4615 oryzias_sinensis ENSOSIP00000000034 81.4004 75.4923 ENSG00000143621 homo_sapiens ENSP00000355011 95.8974 93.8462 pelodiscus_sinensis ENSPSIP00000004994 95.4082 93.3673 ENSG00000143621 homo_sapiens ENSP00000355011 98.7179 97.1795 gopherus_evgoodei ENSGEVP00005023649 98.7179 97.1795 ENSG00000143621 homo_sapiens ENSP00000355011 98.7179 97.1795 chelonoidis_abingdonii ENSCABP00000003856 98.7179 97.1795 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 90 seriola_dumerili ENSSDUP00000013589 96.124 90.6977 ENSG00000143621 homo_sapiens ENSP00000355011 92.0513 85.8974 cottoperca_gobio ENSCGOP00000036594 89.75 83.75 ENSG00000143621 homo_sapiens ENSP00000355011 88.7179 87.1795 struthio_camelus_australis ENSSCUP00000011007 98.2955 96.5909 ENSG00000143621 homo_sapiens ENSP00000355011 88.9744 87.1795 anser_brachyrhynchus ENSABRP00000025252 98.5795 96.5909 ENSG00000143621 homo_sapiens ENSP00000355011 95.1282 89.4872 gasterosteus_aculeatus ENSGACP00000000720 95.8656 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 90.2564 cynoglossus_semilaevis ENSCSEP00000028881 95.6072 90.9561 ENSG00000143621 homo_sapiens ENSP00000355011 94.359 89.4872 poecilia_formosa ENSPFOP00000026466 93.6387 88.8041 ENSG00000143621 homo_sapiens ENSP00000355011 89.4872 84.1026 myripristis_murdjan ENSMMDP00005014061 82.1176 77.1765 ENSG00000143621 homo_sapiens ENSP00000355011 74.6154 66.4103 myripristis_murdjan ENSMMDP00005018925 84.3478 75.0725 ENSG00000143621 homo_sapiens ENSP00000355011 74.8718 66.6667 myripristis_murdjan ENSMMDP00005007538 84.6377 75.3623 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 89.7436 sander_lucioperca ENSSLUP00000003430 96.124 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 98.2051 96.4103 strigops_habroptila ENSSHBP00005020292 92.5121 90.8213 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 89.4872 amphiprion_ocellaris ENSAOCP00000013763 96.124 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 89.2308 87.6923 terrapene_carolina_triunguis ENSTMTP00000025827 98.8636 97.1591 ENSG00000143621 homo_sapiens ENSP00000355011 82.5641 70.5128 hucho_hucho ENSHHUP00000043651 70.614 60.307 ENSG00000143621 homo_sapiens ENSP00000355011 56.4103 47.1795 hucho_hucho ENSHHUP00000036334 83.6502 69.962 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.4872 hucho_hucho ENSHHUP00000079850 95.3488 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.2308 hucho_hucho ENSHHUP00000080883 95.3488 89.9225 ENSG00000143621 homo_sapiens ENSP00000355011 95.1282 89.4872 betta_splendens ENSBSLP00000021087 92.75 87.25 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 89.7436 pygocentrus_nattereri ENSPNAP00000003005 95.6072 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 95.1282 89.7436 anabas_testudineus ENSATEP00000019422 95.8656 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 75.3846 55.8974 ciona_savignyi ENSCSAVP00000012018 75.969 56.3307 ENSG00000143621 homo_sapiens ENSP00000355011 86.4103 81.5385 seriola_lalandi_dorsalis ENSSLDP00000015745 96.5616 91.1175 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 89.2308 labrus_bergylta ENSLBEP00000032113 96.124 89.9225 ENSG00000143621 homo_sapiens ENSP00000355011 78.4615 72.8205 pundamilia_nyererei ENSPNYP00000026034 95.0311 88.1988 ENSG00000143621 homo_sapiens ENSP00000355011 95.641 90 mastacembelus_armatus ENSMAMP00000030323 96.3824 90.6977 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 90 stegastes_partitus ENSSPAP00000005115 96.124 90.6977 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.4872 oncorhynchus_tshawytscha ENSOTSP00005026904 95.3488 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.4872 oncorhynchus_tshawytscha ENSOTSP00005031150 95.3488 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 84.8718 72.3077 oncorhynchus_tshawytscha ENSOTSP00005034341 83.5859 71.2121 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.2308 oncorhynchus_tshawytscha ENSOTSP00005090970 94.8586 89.4602 ENSG00000143621 homo_sapiens ENSP00000355011 70 56.9231 oncorhynchus_tshawytscha ENSOTSP00005040910 75 60.989 ENSG00000143621 homo_sapiens ENSP00000355011 86.6667 81.2821 acanthochromis_polyacanthus ENSAPOP00000007724 96.8481 90.8309 ENSG00000143621 homo_sapiens ENSP00000355011 97.1795 95.3846 aquila_chrysaetos_chrysaetos ENSACCP00020004967 98.6979 96.875 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 88.9744 nothobranchius_furzeri ENSNFUP00015047579 96.124 89.6641 ENSG00000143621 homo_sapiens ENSP00000355011 69.2308 65.1282 cyprinodon_variegatus ENSCVAP00000015616 94.4056 88.8112 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 89.7436 denticeps_clupeoides ENSDCDP00000011477 96.124 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 89.4872 84.6154 larimichthys_crocea ENSLCRP00005037332 72.4066 68.4647 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.2308 takifugu_rubripes ENSTRUP00000076446 88.7019 83.6538 ENSG00000143621 homo_sapiens ENSP00000355011 81.0256 78.2051 ficedula_albicollis ENSFALP00000012577 97.5309 94.1358 ENSG00000143621 homo_sapiens ENSP00000355011 94.1026 87.9487 hippocampus_comes ENSHCOP00000005441 94.832 88.6305 ENSG00000143621 homo_sapiens ENSP00000355011 90 84.6154 cyprinus_carpio_carpio ENSCCRP00000089760 89.0863 83.7563 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.7436 cyprinus_carpio_carpio ENSCCRP00000087680 92.7136 87.9397 ENSG00000143621 homo_sapiens ENSP00000355011 88.9744 87.1795 coturnix_japonica ENSCJPP00005017260 98.5795 96.5909 ENSG00000143621 homo_sapiens ENSP00000355011 94.359 89.4872 poecilia_latipinna ENSPLAP00000000391 95.0904 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 52.3077 47.4359 sinocyclocheilus_grahami ENSSGRP00000009058 87.5536 79.3991 ENSG00000143621 homo_sapiens ENSP00000355011 94.8718 90 sinocyclocheilus_grahami ENSSGRP00000072560 95.6072 90.6977 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 89.7436 maylandia_zebra ENSMZEP00005023380 96.124 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 90.7692 85.1282 tetraodon_nigroviridis ENSTNIP00000007671 91.2371 85.567 ENSG00000143621 homo_sapiens ENSP00000355011 88.9744 83.5897 tetraodon_nigroviridis ENSTNIP00000002255 87.6263 82.3232 ENSG00000143621 homo_sapiens ENSP00000355011 94.6154 89.7436 paramormyrops_kingsleyae ENSPKIP00000035299 95.3488 90.4393 ENSG00000143621 homo_sapiens ENSP00000355011 95.641 90.5128 scleropages_formosus ENSSFOP00015015803 96.3824 91.2145 ENSG00000143621 homo_sapiens ENSP00000355011 92.8205 85.1282 leptobrachium_leishanense ENSLLEP00000032153 93.299 85.567 ENSG00000143621 homo_sapiens ENSP00000355011 95.1282 89.4872 scophthalmus_maximus ENSSMAP00000034036 95.8656 90.1809 ENSG00000143621 homo_sapiens ENSP00000355011 95.3846 88.4615 oryzias_melastigma ENSOMEP00000007579 96.124 89.1473
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003677 enables DNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0003725 enables double-stranded RNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005576 located_in extracellular region 2 HDA,TAS Homo_sapiens(9606) Component GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 IDA Homo_sapiens(9606) Component GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0035580 located_in specific granule lumen 1 TAS Homo_sapiens(9606) Component GO:0045893 involved_in positive regulation of DNA-templated transcription 2 IBA,IDA Homo_sapiens(9606) Process GO:1904724 located_in tertiary granule lumen 1 TAS Homo_sapiens(9606) Component GO:1904813 located_in ficolin-1-rich granule lumen 1 TAS Homo_sapiens(9606) Component GO:1990904 part_of ribonucleoprotein complex 1 IDA Homo_sapiens(9606) Component
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