RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	DataSet_01_441 DataSet_01_84

Ensembl ID	ENSG00000143368	Gene ID	10262	Accession	10771
Symbol	SF3B4	Alias	AFD1;Hsh49;SAP49;SF3b49	Full Name	splicing factor 3b subunit 4
Status	Confidence	Length	4487 bases	Strand	Minus strand
Position	1 : 149923317 - 149927803	RNA binding domain	RRM_1
Summary	This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000271628	RRM_1	PF00076	3.1e-38	1
ENSP00000271628	RRM_1	PF00076	3.1e-38	2
ENSP00000391114	RRM_1	PF00076	8.4e-31	1
ENSP00000391114	RRM_1	PF00076	8.4e-31	2

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
36639679	SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.	Zhan Yang	2023-01-13	Cell death & disease
35030977	Enabled homolog (ENAH) regulated by RNA binding protein splicing factor 3b subunit 4 (SF3B4) exacerbates the proliferation, invasion and migration of hepatocellular carcinoma cells via Notch signaling pathway.	Guoming Deng	2022-02-01	Bioengineered
33067435	Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry.	Alexandra Stützer	2020-10-16	Nature communications
35082828	Sequence Divergence and Functional Specializations of the Ancient Spliceosomal SF3b: Implications in Flexibility and Adaptations of the Multi-Protein Complex.	Arangasamy Yazhini	2021-01-01	Frontiers in genetics
32140746	The SF3b complex: splicing and beyond.	Chengfu Sun	2020-09-01	Cellular and molecular life sciences : CMLS
35210412	SF3B4 promotes ovarian cancer progression by regulating alternative splicing of RAD52.	Yuchao Diao	2022-02-24	Cell death & disease
35852380	Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer.	L Aaron Slusher	2022-10-04	Molecular cancer research : MCR

Name	Transcript ID	bp	Protein	Translation ID
SF3B4-201	ENST00000271628	1544	424aa	ENSP00000271628
SF3B4-202	ENST00000457312	826	190aa	ENSP00000391114

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000143368	homo_sapiens	ENSP00000286070	21.519	12.0253	homo_sapiens	ENSP00000271628	24.0566	13.4434
ENSG00000143368	homo_sapiens	ENSP00000294904	30.0493	19.2118	homo_sapiens	ENSP00000271628	28.7736	18.3962
ENSG00000143368	homo_sapiens	ENSP00000313007	22.6415	14.1509	homo_sapiens	ENSP00000271628	33.9623	21.2264
ENSG00000143368	homo_sapiens	ENSP00000281589	22.0285	13.6292	homo_sapiens	ENSP00000271628	32.783	20.283
ENSG00000143368	homo_sapiens	ENSP00000352162	36.7847	23.9782	homo_sapiens	ENSP00000271628	31.8396	20.7547
ENSG00000143368	homo_sapiens	ENSP00000304405	20.3791	12.7962	homo_sapiens	ENSP00000271628	30.4245	19.1038
ENSG00000143368	homo_sapiens	ENSP00000358635	20.2247	12.8411	homo_sapiens	ENSP00000271628	29.717	18.8679
ENSG00000143368	homo_sapiens	ENSP00000308012	25.1309	13.8743	homo_sapiens	ENSP00000271628	22.6415	12.5
ENSG00000143368	homo_sapiens	ENSP00000385269	39.8773	24.5399	homo_sapiens	ENSP00000271628	30.6604	18.8679
ENSG00000143368	homo_sapiens	ENSP00000262031	30.9582	20.6388	homo_sapiens	ENSP00000271628	29.717	19.8113
ENSG00000143368	homo_sapiens	ENSP00000386226	22.3256	12.3256	homo_sapiens	ENSP00000271628	22.6415	12.5
ENSG00000143368	homo_sapiens	ENSP00000311747	17.7877	11.2108	homo_sapiens	ENSP00000271628	28.066	17.6887
ENSG00000143368	homo_sapiens	ENSP00000348538	29.2887	19.2469	homo_sapiens	ENSP00000271628	16.5094	10.8491
ENSG00000143368	homo_sapiens	ENSP00000360889	37.1585	23.224	homo_sapiens	ENSP00000271628	32.0755	20.0472
ENSG00000143368	homo_sapiens	ENSP00000368341	31.7797	21.6102	homo_sapiens	ENSP00000271628	17.6887	12.0283
ENSG00000143368	homo_sapiens	ENSP00000380479	38.4401	23.6769	homo_sapiens	ENSP00000271628	32.5472	20.0472
ENSG00000143368	homo_sapiens	ENSP00000463233	28.9189	16.4865	homo_sapiens	ENSP00000271628	25.2358	14.3868
ENSG00000143368	homo_sapiens	ENSP00000361949	21.9697	13.7879	homo_sapiens	ENSP00000271628	34.1981	21.4623
ENSG00000143368	homo_sapiens	ENSP00000434359	22.3614	12.7013	homo_sapiens	ENSP00000271628	29.4811	16.7453
ENSG00000143368	homo_sapiens	ENSP00000373277	28.6041	18.9931	homo_sapiens	ENSP00000271628	29.4811	19.5755
ENSG00000143368	homo_sapiens	ENSP00000240185	21.256	12.3188	homo_sapiens	ENSP00000271628	20.7547	12.0283
ENSG00000143368	homo_sapiens	ENSP00000217073	23.1018	15.3473	homo_sapiens	ENSP00000271628	33.7264	22.4057
ENSG00000143368	homo_sapiens	ENSP00000362621	27.5	16.5	homo_sapiens	ENSP00000271628	12.9717	7.78302
ENSG00000143368	homo_sapiens	ENSP00000362618	27.5	16.5	homo_sapiens	ENSP00000271628	12.9717	7.78302

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000143368	homo_sapiens	ENSP00000271628	74.7642	70.0472	nomascus_leucogenys	ENSNLEP00000011795	91.8841	86.087
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	pan_paniscus	ENSPPAP00000036260	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	pongo_abelii	ENSPPYP00000001065	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	pan_troglodytes	ENSPTRP00000002107	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	gorilla_gorilla	ENSGGOP00000004665	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	67.9245	64.3868	ornithorhynchus_anatinus	ENSOANP00000034167	53.2347	50.4621
ENSG00000143368	homo_sapiens	ENSP00000271628	77.1226	76.8868	notamacropus_eugenii	ENSMEUP00000002983	81.3433	81.0945
ENSG00000143368	homo_sapiens	ENSP00000271628	81.3679	78.3019	dasypus_novemcinctus	ENSDNOP00000020909	87.3418	84.0506
ENSG00000143368	homo_sapiens	ENSP00000271628	95.9906	95.0472	dasypus_novemcinctus	ENSDNOP00000025563	97.3684	96.4115
ENSG00000143368	homo_sapiens	ENSP00000271628	90.0943	90.0943	echinops_telfairi	ENSETEP00000007278	90.3073	90.3073
ENSG00000143368	homo_sapiens	ENSP00000271628	100	99.7642	callithrix_jacchus	ENSCJAP00000066428	100	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	cercocebus_atys	ENSCATP00000018582	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	macaca_fascicularis	ENSMFAP00000030430	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	macaca_mulatta	ENSMMUP00000009515	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	macaca_nemestrina	ENSMNEP00000015484	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	papio_anubis	ENSPANP00000002232	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	mandrillus_leucophaeus	ENSMLEP00000028918	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	tursiops_truncatus	ENSTTRP00000004915	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	91.0377	91.0377	vulpes_vulpes	ENSVVUP00000010461	98.7212	98.7212
ENSG00000143368	homo_sapiens	ENSP00000271628	70.9906	67.6887	vulpes_vulpes	ENSVVUP00000031135	63.1027	60.1677
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	mus_spretus	MGP_SPRETEiJ_P0061678	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	equus_asinus	ENSEASP00005001860	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	66.9811	63.9151	capra_hircus	ENSCHIP00000002869	77.3842	73.842
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	capra_hircus	ENSCHIP00000031211	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.5283	loxodonta_africana	ENSLAFP00000007164	99.2941	99.2941
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	panthera_leo	ENSPLOP00000024146	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	ailuropoda_melanoleuca	ENSAMEP00000010585	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	91.9811	91.9811	bos_indicus_hybrid	ENSBIXP00005038343	93.9759	93.9759
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	bos_indicus_hybrid	ENSBIXP00005042193	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	oryctolagus_cuniculus	ENSOCUP00000003976	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.2924	canis_lupus_familiaris	ENSCAFP00845016972	99.5283	99.2924
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	panthera_pardus	ENSPPRP00000014517	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	39.8585	37.0283	marmota_marmota_marmota	ENSMMMP00000009964	84.5	78.5
ENSG00000143368	homo_sapiens	ENSP00000271628	96.6981	96.6981	marmota_marmota_marmota	ENSMMMP00000022312	96.9267	96.9267
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	balaenoptera_musculus	ENSBMSP00010005316	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.5283	cavia_porcellus	ENSCPOP00000007432	99.5283	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	felis_catus	ENSFCAP00000009381	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	ursus_americanus	ENSUAMP00000029144	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	97.8774	96.934	monodelphis_domestica	ENSMODP00000059307	92.8412	91.9463
ENSG00000143368	homo_sapiens	ENSP00000271628	26.4151	26.1792	bison_bison_bison	ENSBBBP00000007755	91.0569	90.2439
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	bison_bison_bison	ENSBBBP00000015604	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	monodon_monoceros	ENSMMNP00015000591	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.5283	sus_scrofa	ENSSSCP00000007108	99.5283	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	microcebus_murinus	ENSMICP00000049039	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	79.717	76.6509	octodon_degus	ENSODEP00000004730	88.2507	84.8564
ENSG00000143368	homo_sapiens	ENSP00000271628	68.1604	65.3302	octodon_degus	ENSODEP00000012023	83.046	79.5977
ENSG00000143368	homo_sapiens	ENSP00000271628	54.4811	54.2453	jaculus_jaculus	ENSJJAP00000022443	98.7179	98.2906
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	ovis_aries_rambouillet	ENSOARP00020009015	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	98.8208	98.5849	ursus_maritimus	ENSUMAP00000004742	99.2891	99.0521
ENSG00000143368	homo_sapiens	ENSP00000271628	96.6981	96.4623	ochotona_princeps	ENSOPRP00000009869	97.1564	96.9194
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	delphinapterus_leucas	ENSDLEP00000013788	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	physeter_catodon	ENSPCTP00005015579	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.2924	mus_caroli	MGP_CAROLIEiJ_P0059301	99.5283	99.2924
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	mus_musculus	ENSMUSP00000075709	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	dipodomys_ordii	ENSDORP00000015400	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	mustela_putorius_furo	ENSMPUP00000005521	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	aotus_nancymaae	ENSANAP00000026605	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	73.8208	70.7547	saimiri_boliviensis_boliviensis	ENSSBOP00000017030	79.6438	76.3359
ENSG00000143368	homo_sapiens	ENSP00000271628	100	99.7642	saimiri_boliviensis_boliviensis	ENSSBOP00000002367	100	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	96.934	96.934	vicugna_pacos	ENSVPAP00000007587	99.7573	99.7573
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	chlorocebus_sabaeus	ENSCSAP00000014147	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	mesocricetus_auratus	ENSMAUP00000015949	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	phocoena_sinus	ENSPSNP00000001600	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	camelus_dromedarius	ENSCDRP00005022646	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	carlito_syrichta	ENSTSYP00000008533	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.2924	panthera_tigris_altaica	ENSPTIP00000015462	99.5283	99.2924
ENSG00000143368	homo_sapiens	ENSP00000271628	97.8774	97.4057	rattus_norvegicus	ENSRNOP00000028758	96.7366	96.2704
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	prolemur_simus	ENSPSMP00000003764	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	92.6887	92.217	microtus_ochrogaster	ENSMOCP00000014753	97.2772	96.7822
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	microtus_ochrogaster	ENSMOCP00000014037	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	peromyscus_maniculatus_bairdii	ENSPEMP00000019200	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	75.9434	73.3491	bos_mutus	ENSBMUP00000012772	81.7259	78.934
ENSG00000143368	homo_sapiens	ENSP00000271628	99.2924	99.2924	bos_mutus	ENSBMUP00000031194	99.2924	99.2924
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	mus_spicilegus	ENSMSIP00000009071	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	cricetulus_griseus_chok1gshd	ENSCGRP00001003060	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	pteropus_vampyrus	ENSPVAP00000013354	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	myotis_lucifugus	ENSMLUP00000009824	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.0566	vombatus_ursinus	ENSVURP00010001085	99.5283	99.0566
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.0566	vombatus_ursinus	ENSVURP00010020594	99.5283	99.0566
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	98.8208	rhinolophus_ferrumequinum	ENSRFEP00010029578	99.5283	98.8208
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	neovison_vison	ENSNVIP00000003943	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	bos_taurus	ENSBTAP00000016577	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	87.0283	87.0283	bos_taurus	ENSBTAP00000059270	90.6634	90.6634
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.5283	heterocephalus_glaber_female	ENSHGLP00000017258	90.364	90.364
ENSG00000143368	homo_sapiens	ENSP00000271628	92.9245	92.4528	heterocephalus_glaber_female	ENSHGLP00000036337	92.9245	92.4528
ENSG00000143368	homo_sapiens	ENSP00000271628	99.0566	99.0566	rhinopithecus_bieti	ENSRBIP00000039895	98.8235	98.8235
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.2924	canis_lupus_dingo	ENSCAFP00020025149	99.5283	99.2924
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	sciurus_vulgaris	ENSSVLP00005000391	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.0566	phascolarctos_cinereus	ENSPCIP00000010816	99.5283	99.0566
ENSG00000143368	homo_sapiens	ENSP00000271628	67.217	67.217	procavia_capensis	ENSPCAP00000000370	68.1818	68.1818
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.2924	nannospalax_galili	ENSNGAP00000015262	99.5283	99.2924
ENSG00000143368	homo_sapiens	ENSP00000271628	93.1604	92.6887	bos_grunniens	ENSBGRP00000000819	87.9733	87.5278
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	bos_grunniens	ENSBGRP00000026607	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.5283	chinchilla_lanigera	ENSCLAP00000023090	99.5283	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	cervus_hanglu_yarkandensis	ENSCHYP00000021944	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	95.0472	94.1038	cervus_hanglu_yarkandensis	ENSCHYP00000020741	95.0472	94.1038
ENSG00000143368	homo_sapiens	ENSP00000271628	99.5283	99.5283	catagonus_wagneri	ENSCWAP00000013184	99.5283	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	ictidomys_tridecemlineatus	ENSSTOP00000000612	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	73.3491	70.0472	ictidomys_tridecemlineatus	ENSSTOP00000028619	76.601	73.1527
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	otolemur_garnettii	ENSOGAP00000005595	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	94.5755	94.5755	cebus_imitator	ENSCCAP00000008033	90.5192	90.5192
ENSG00000143368	homo_sapiens	ENSP00000271628	85.3774	83.0189	cebus_imitator	ENSCCAP00000004579	85.9857	83.6105
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	urocitellus_parryii	ENSUPAP00010001850	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	moschus_moschiferus	ENSMMSP00000028076	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	100	100	rhinopithecus_roxellana	ENSRROP00000009884	100	100
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.5283	mus_pahari	MGP_PahariEiJ_P0070261	99.7642	99.5283
ENSG00000143368	homo_sapiens	ENSP00000271628	99.7642	99.7642	propithecus_coquereli	ENSPCOP00000008233	99.7642	99.7642
ENSG00000143368	homo_sapiens	ENSP00000271628	63.6792	56.8396	caenorhabditis_elegans	C08B11.5.1	69.5876	62.1134
ENSG00000143368	homo_sapiens	ENSP00000271628	61.0849	55.4245	drosophila_melanogaster	FBpp0070859	74.6398	67.7233
ENSG00000143368	homo_sapiens	ENSP00000271628	65.8019	60.8491	ciona_intestinalis	ENSCINP00000004818	74.4	68.8
ENSG00000143368	homo_sapiens	ENSP00000271628	75.9434	71.934	petromyzon_marinus	ENSPMAP00000008629	75.9434	71.934
ENSG00000143368	homo_sapiens	ENSP00000271628	61.7925	58.2547	eptatretus_burgeri	ENSEBUP00000017910	74.221	69.9717
ENSG00000143368	homo_sapiens	ENSP00000271628	73.8208	70.7547	latimeria_chalumnae	ENSLACP00000004989	86.2259	82.6446
ENSG00000143368	homo_sapiens	ENSP00000271628	85.6132	80.6604	lepisosteus_oculatus	ENSLOCP00000011024	86.019	81.0427
ENSG00000143368	homo_sapiens	ENSP00000271628	77.8302	74.2924	clupea_harengus	ENSCHAP00000012949	82.0896	78.3582
ENSG00000143368	homo_sapiens	ENSP00000271628	79.4811	76.4151	danio_rerio	ENSDARP00000022759	84.25	81
ENSG00000143368	homo_sapiens	ENSP00000271628	78.3019	73.3491	carassius_auratus	ENSCARP00000058379	77.7518	72.8337
ENSG00000143368	homo_sapiens	ENSP00000271628	78.5377	75.2358	carassius_auratus	ENSCARP00000036743	84.5178	80.9645
ENSG00000143368	homo_sapiens	ENSP00000271628	80.1887	76.1792	astyanax_mexicanus	ENSAMXP00000008515	84.788	80.5486
ENSG00000143368	homo_sapiens	ENSP00000271628	78.066	75	ictalurus_punctatus	ENSIPUP00000018066	80.9291	77.7506
ENSG00000143368	homo_sapiens	ENSP00000271628	79.2453	75	esox_lucius	ENSELUP00000012674	84.6348	80.1008
ENSG00000143368	homo_sapiens	ENSP00000271628	80.6604	76.8868	electrophorus_electricus	ENSEEEP00000050840	84.6535	80.6931
ENSG00000143368	homo_sapiens	ENSP00000271628	63.4434	59.9057	oncorhynchus_kisutch	ENSOKIP00005066327	70.6037	66.6667
ENSG00000143368	homo_sapiens	ENSP00000271628	80.6604	76.4151	oncorhynchus_kisutch	ENSOKIP00005035596	85.5	81
ENSG00000143368	homo_sapiens	ENSP00000271628	80.8962	76.6509	oncorhynchus_mykiss	ENSOMYP00000068878	85.75	81.25
ENSG00000143368	homo_sapiens	ENSP00000271628	63.2075	59.1981	oncorhynchus_mykiss	ENSOMYP00000025807	70.5263	66.0526
ENSG00000143368	homo_sapiens	ENSP00000271628	75.9434	72.6415	salmo_salar	ENSSSAP00000015354	78.9216	75.4902
ENSG00000143368	homo_sapiens	ENSP00000271628	72.1698	65.566	salmo_salar	ENSSSAP00000022541	74.2718	67.4757
ENSG00000143368	homo_sapiens	ENSP00000271628	80.6604	76.4151	salmo_trutta	ENSSTUP00000063029	85.9296	81.407
ENSG00000143368	homo_sapiens	ENSP00000271628	80.8962	76.6509	salmo_trutta	ENSSTUP00000108254	85.75	81.25
ENSG00000143368	homo_sapiens	ENSP00000271628	79.717	75.7076	gadus_morhua	ENSGMOP00000002653	84.9246	80.6533
ENSG00000143368	homo_sapiens	ENSP00000271628	77.3585	73.5849	fundulus_heteroclitus	ENSFHEP00000007131	47.6052	45.283
ENSG00000143368	homo_sapiens	ENSP00000271628	72.4057	67.4528	poecilia_reticulata	ENSPREP00000016377	76.1787	70.9677
ENSG00000143368	homo_sapiens	ENSP00000271628	79.0094	75.2358	xiphophorus_maculatus	ENSXMAP00000003789	85.6777	81.5857
ENSG00000143368	homo_sapiens	ENSP00000271628	77.8302	74.0566	oryzias_latipes	ENSORLP00000003820	82.7068	78.6967
ENSG00000143368	homo_sapiens	ENSP00000271628	78.5377	74.7642	cyclopterus_lumpus	ENSCLMP00005004084	84.7328	80.6616
ENSG00000143368	homo_sapiens	ENSP00000271628	72.1698	66.2736	oreochromis_niloticus	ENSONIP00000003422	72.6841	66.7458
ENSG00000143368	homo_sapiens	ENSP00000271628	80.1887	76.1792	haplochromis_burtoni	ENSHBUP00000022006	84.788	80.5486
ENSG00000143368	homo_sapiens	ENSP00000271628	80.1887	76.1792	astatotilapia_calliptera	ENSACLP00000020963	84.788	80.5486
ENSG00000143368	homo_sapiens	ENSP00000271628	80.1887	76.1792	sparus_aurata	ENSSAUP00010002794	85.4271	81.1558
ENSG00000143368	homo_sapiens	ENSP00000271628	80.6604	76.8868	lates_calcarifer	ENSLCAP00010030459	84.8635	80.8933
ENSG00000143368	homo_sapiens	ENSP00000271628	78.066	74.5283	xenopus_tropicalis	ENSXETP00000059096	81.1274	77.451
ENSG00000143368	homo_sapiens	ENSP00000271628	90.8019	88.9151	chrysemys_picta_bellii	ENSCPBP00000010469	92.1053	90.1914
ENSG00000143368	homo_sapiens	ENSP00000271628	81.6038	79.9528	sphenodon_punctatus	ENSSPUP00000001288	86.7168	84.9624
ENSG00000143368	homo_sapiens	ENSP00000271628	90.566	88.6792	crocodylus_porosus	ENSCPRP00005012792	92.0863	90.1679
ENSG00000143368	homo_sapiens	ENSP00000271628	90.0943	87.9717	laticauda_laticaudata	ENSLLTP00000020456	83.2244	81.2636
ENSG00000143368	homo_sapiens	ENSP00000271628	91.0377	88.9151	notechis_scutatus	ENSNSUP00000010881	92.5659	90.4077
ENSG00000143368	homo_sapiens	ENSP00000271628	91.0377	88.9151	pseudonaja_textilis	ENSPTXP00000013810	92.5659	90.4077
ENSG00000143368	homo_sapiens	ENSP00000271628	71.4623	68.6321	anas_platyrhynchos_platyrhynchos	ENSAPLP00000031097	82.7869	79.5082
ENSG00000143368	homo_sapiens	ENSP00000271628	90.0943	87.9717	gallus_gallus	ENSGALP00010042994	91.3876	89.2345
ENSG00000143368	homo_sapiens	ENSP00000271628	81.3679	78.3019	meleagris_gallopavo	ENSMGAP00000020140	60.5263	58.2456
ENSG00000143368	homo_sapiens	ENSP00000271628	67.217	65.8019	serinus_canaria	ENSSCAP00000016088	65.9722	64.5833
ENSG00000143368	homo_sapiens	ENSP00000271628	90.3302	88.2076	parus_major	ENSPMJP00000002013	71.3222	69.6462
ENSG00000143368	homo_sapiens	ENSP00000271628	79.2453	75.7076	anolis_carolinensis	ENSACAP00000032157	79.6208	76.0664
ENSG00000143368	homo_sapiens	ENSP00000271628	71.934	66.0377	neolamprologus_brichardi	ENSNBRP00000017982	73.6715	67.6329
ENSG00000143368	homo_sapiens	ENSP00000271628	91.0377	88.9151	naja_naja	ENSNNAP00000024504	92.5659	90.4077
ENSG00000143368	homo_sapiens	ENSP00000271628	79.4811	75.9434	podarcis_muralis	ENSPMRP00000027815	68.7755	65.7143
ENSG00000143368	homo_sapiens	ENSP00000271628	66.5094	63.2075	taeniopygia_guttata	ENSTGUP00000024969	40.8696	38.8406
ENSG00000143368	homo_sapiens	ENSP00000271628	85.1415	80.6604	erpetoichthys_calabaricus	ENSECRP00000002037	84.1492	79.7203
ENSG00000143368	homo_sapiens	ENSP00000271628	78.7736	74.7642	kryptolebias_marmoratus	ENSKMAP00000010860	84.9873	80.6616
ENSG00000143368	homo_sapiens	ENSP00000271628	91.0377	88.2076	salvator_merianae	ENSSMRP00000009905	92.5659	89.6882
ENSG00000143368	homo_sapiens	ENSP00000271628	78.066	73.8208	oryzias_javanicus	ENSOJAP00000045184	83.3753	78.8413
ENSG00000143368	homo_sapiens	ENSP00000271628	69.8113	66.9811	amphilophus_citrinellus	ENSACIP00000023767	88.0952	84.5238
ENSG00000143368	homo_sapiens	ENSP00000271628	79.9528	76.1792	dicentrarchus_labrax	ENSDLAP00005080065	76.5237	72.912
ENSG00000143368	homo_sapiens	ENSP00000271628	81.1321	77.1226	amphiprion_percula	ENSAPEP00000014533	86	81.75
ENSG00000143368	homo_sapiens	ENSP00000271628	77.5943	73.8208	oryzias_sinensis	ENSOSIP00000038647	82.4561	78.4461
ENSG00000143368	homo_sapiens	ENSP00000271628	54.4811	52.8302	pelodiscus_sinensis	ENSPSIP00000010535	84.9265	82.3529
ENSG00000143368	homo_sapiens	ENSP00000271628	90.566	88.6792	gopherus_evgoodei	ENSGEVP00005018575	91.866	89.9522
ENSG00000143368	homo_sapiens	ENSP00000271628	90.566	88.6792	chelonoidis_abingdonii	ENSCABP00000024927	91.866	89.9522
ENSG00000143368	homo_sapiens	ENSP00000271628	80.4245	76.4151	seriola_dumerili	ENSSDUP00000016503	84.6154	80.397
ENSG00000143368	homo_sapiens	ENSP00000271628	80.1887	76.1792	cottoperca_gobio	ENSCGOP00000017563	84.788	80.5486
ENSG00000143368	homo_sapiens	ENSP00000271628	71.2264	68.8679	struthio_camelus_australis	ENSSCUP00000000234	86.0399	83.1909
ENSG00000143368	homo_sapiens	ENSP00000271628	73.1132	71.4623	anser_brachyrhynchus	ENSABRP00000009607	89.8551	87.8261
ENSG00000143368	homo_sapiens	ENSP00000271628	79.0094	74.7642	gasterosteus_aculeatus	ENSGACP00000005037	84.8101	80.2532
ENSG00000143368	homo_sapiens	ENSP00000271628	80.8962	77.3585	cynoglossus_semilaevis	ENSCSEP00000023933	71.6075	68.476
ENSG00000143368	homo_sapiens	ENSP00000271628	79.0094	75	poecilia_formosa	ENSPFOP00000005679	85.0254	80.7107
ENSG00000143368	homo_sapiens	ENSP00000271628	81.3679	77.1226	myripristis_murdjan	ENSMMDP00005009764	85.6079	81.1414
ENSG00000143368	homo_sapiens	ENSP00000271628	79.9528	75.9434	sander_lucioperca	ENSSLUP00000003271	84.5387	80.2993
ENSG00000143368	homo_sapiens	ENSP00000271628	90.566	88.4434	strigops_habroptila	ENSSHBP00005007895	91.866	89.7129
ENSG00000143368	homo_sapiens	ENSP00000271628	81.1321	77.1226	amphiprion_ocellaris	ENSAOCP00000015082	86	81.75
ENSG00000143368	homo_sapiens	ENSP00000271628	90.8019	88.9151	terrapene_carolina_triunguis	ENSTMTP00000004529	92.1053	90.1914
ENSG00000143368	homo_sapiens	ENSP00000271628	27.1226	25.9434	hucho_hucho	ENSHHUP00000020133	88.4615	84.6154
ENSG00000143368	homo_sapiens	ENSP00000271628	80.8962	76.6509	hucho_hucho	ENSHHUP00000026169	85.75	81.25
ENSG00000143368	homo_sapiens	ENSP00000271628	79.9528	75.9434	betta_splendens	ENSBSLP00000038243	84.1191	79.9007
ENSG00000143368	homo_sapiens	ENSP00000271628	80.4245	76.6509	pygocentrus_nattereri	ENSPNAP00000023573	86.9898	82.9082
ENSG00000143368	homo_sapiens	ENSP00000271628	80.6604	76.4151	anabas_testudineus	ENSATEP00000018437	84.8635	80.397
ENSG00000143368	homo_sapiens	ENSP00000271628	47.8774	44.8113	ciona_savignyi	ENSCSAVP00000013305	67.4419	63.1229
ENSG00000143368	homo_sapiens	ENSP00000271628	28.3019	17.9245	saccharomyces_cerevisiae	YOR319W	56.338	35.6808
ENSG00000143368	homo_sapiens	ENSP00000271628	80.6604	76.6509	seriola_lalandi_dorsalis	ENSSLDP00000018064	84.8635	80.6452
ENSG00000143368	homo_sapiens	ENSP00000271628	79.2453	75.7076	labrus_bergylta	ENSLBEP00000035763	84.2105	80.4511
ENSG00000143368	homo_sapiens	ENSP00000271628	80.1887	76.1792	pundamilia_nyererei	ENSPNYP00000016766	84.788	80.5486
ENSG00000143368	homo_sapiens	ENSP00000271628	80.1887	76.6509	mastacembelus_armatus	ENSMAMP00000021841	85.213	81.4536
ENSG00000143368	homo_sapiens	ENSP00000271628	80.4245	76.8868	stegastes_partitus	ENSSPAP00000025419	84.8259	81.0945
ENSG00000143368	homo_sapiens	ENSP00000271628	80.8962	76.6509	oncorhynchus_tshawytscha	ENSOTSP00005014185	85.75	81.25
ENSG00000143368	homo_sapiens	ENSP00000271628	60.6132	58.4906	oncorhynchus_tshawytscha	ENSOTSP00005082376	76.2611	73.5905
ENSG00000143368	homo_sapiens	ENSP00000271628	81.1321	77.1226	acanthochromis_polyacanthus	ENSAPOP00000014744	86	81.75
ENSG00000143368	homo_sapiens	ENSP00000271628	81.1321	79.2453	aquila_chrysaetos_chrysaetos	ENSACCP00020003758	90.5263	88.4211
ENSG00000143368	homo_sapiens	ENSP00000271628	78.7736	74.2924	nothobranchius_furzeri	ENSNFUP00015027751	85.641	80.7692
ENSG00000143368	homo_sapiens	ENSP00000271628	76.6509	72.4057	cyprinodon_variegatus	ENSCVAP00000022717	83.5476	78.9203
ENSG00000143368	homo_sapiens	ENSP00000271628	79.4811	75.2358	denticeps_clupeoides	ENSDCDP00000062453	84.4612	79.9499
ENSG00000143368	homo_sapiens	ENSP00000271628	80.4245	76.8868	larimichthys_crocea	ENSLCRP00005018425	85.6784	81.9095
ENSG00000143368	homo_sapiens	ENSP00000271628	27.1226	20.9906	takifugu_rubripes	ENSTRUP00000010718	28.9673	22.4181
ENSG00000143368	homo_sapiens	ENSP00000271628	77.5943	74.5283	hippocampus_comes	ENSHCOP00000001959	82.4561	79.198
ENSG00000143368	homo_sapiens	ENSP00000271628	81.3679	77.3585	cyprinus_carpio_carpio	ENSCCRP00000124864	85.6079	81.3896
ENSG00000143368	homo_sapiens	ENSP00000271628	74.0566	69.5755	cyprinus_carpio_carpio	ENSCCRP00000019565	65.9664	61.9748
ENSG00000143368	homo_sapiens	ENSP00000271628	89.8585	87.5	coturnix_japonica	ENSCJPP00005017084	91.1483	88.756
ENSG00000143368	homo_sapiens	ENSP00000271628	71.934	68.3962	poecilia_latipinna	ENSPLAP00000000565	84.2541	80.1105
ENSG00000143368	homo_sapiens	ENSP00000271628	68.3962	63.9151	sinocyclocheilus_grahami	ENSSGRP00000011876	79.6703	74.4505
ENSG00000143368	homo_sapiens	ENSP00000271628	52.3585	50.4717	sinocyclocheilus_grahami	ENSSGRP00000002006	95.279	91.8455
ENSG00000143368	homo_sapiens	ENSP00000271628	80.1887	76.1792	maylandia_zebra	ENSMZEP00005035814	84.788	80.5486
ENSG00000143368	homo_sapiens	ENSP00000271628	76.1792	72.4057	tetraodon_nigroviridis	ENSTNIP00000012017	82.6087	78.5166
ENSG00000143368	homo_sapiens	ENSP00000271628	81.3679	77.1226	paramormyrops_kingsleyae	ENSPKIP00000002984	86.4662	81.9549
ENSG00000143368	homo_sapiens	ENSP00000271628	81.3679	77.8302	scleropages_formosus	ENSSFOP00015013725	85.6079	81.8859
ENSG00000143368	homo_sapiens	ENSP00000271628	79.0094	76.1792	leptobrachium_leishanense	ENSLLEP00000045564	75.4504	72.7477
ENSG00000143368	homo_sapiens	ENSP00000271628	79.717	75.7076	scophthalmus_maximus	ENSSMAP00000011070	84.5	80.25
ENSG00000143368	homo_sapiens	ENSP00000271628	77.8302	73.3491	oryzias_melastigma	ENSOMEP00000012327	83.1234	78.3375

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000375	involved_in RNA splicing, via transesterification reactions	1	TAS	Homo_sapiens(9606)	Process
GO:0000398	involved_in mRNA splicing, via spliceosome	3	IC,IDA,NAS	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	2	HDA,IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	2	IDA,NAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005681	part_of spliceosomal complex	2	IDA,NAS	Homo_sapiens(9606)	Component
GO:0005684	part_of U2-type spliceosomal complex	1	IPI	Homo_sapiens(9606)	Component
GO:0005686	part_of U2 snRNP	2	IBA,NAS	Homo_sapiens(9606)	Component
GO:0005689	part_of U12-type spliceosomal complex	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0006397	involved_in mRNA processing	1	TAS	Homo_sapiens(9606)	Process
GO:0008380	involved_in RNA splicing	1	TAS	Homo_sapiens(9606)	Process
GO:0048026	involved_in positive regulation of mRNA splicing, via spliceosome	1	IBA	Homo_sapiens(9606)	Process
GO:0071005	part_of U2-type precatalytic spliceosome	1	IDA	Homo_sapiens(9606)	Component
GO:1903241	involved_in U2-type prespliceosome assembly	1	NAS	Homo_sapiens(9606)	Process
GO:1990935	enables splicing factor binding	1	IDA	Homo_sapiens(9606)	Function