Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000141510 Gene ID 7157 Accession 11998
Symbol TP53 Alias P53;BCC7;LFS1;BMFS5;TRP53 Full Name tumor protein p53
Status Confidence Length 25760 bases Strand Minus strand
Position 17 : 7661779 - 7687538 RNA binding domain N.A.
Summary This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
TP53-203 ENST00000413465 1018 285aa ENSP00000410739
TP53-227 ENST00000635293 1883 410aa ENSP00000488924
TP53-202 ENST00000359597 1152 343aa ENSP00000352610
TP53-208 ENST00000504290 2331 214aa ENSP00000484409
TP53-209 ENST00000504937 2271 261aa ENSP00000481179
TP53-213 ENST00000510385 2404 209aa ENSP00000478499
TP53-221 ENST00000610623 2331 187aa ENSP00000477531
TP53-222 ENST00000618944 2404 182aa ENSP00000481401
TP53-223 ENST00000619186 2271 234aa ENSP00000484375
TP53-219 ENST00000610292 2639 354aa ENSP00000478219
TP53-225 ENST00000620739 2579 354aa ENSP00000481638
TP53-204 ENST00000420246 2653 341aa ENSP00000391127
TP53-206 ENST00000455263 2580 346aa ENSP00000398846
TP53-220 ENST00000610538 2580 307aa ENSP00000480868
TP53-226 ENST00000622645 2653 302aa ENSP00000482222
TP53-211 ENST00000508793 2660 393aa ENSP00000424104
TP53-207 ENST00000503591 2552 393aa ENSP00000426252
TP53-214 ENST00000514944 2170 300aa ENSP00000423862
TP53-205 ENST00000445888 2506 393aa ENSP00000391478
TP53-212 ENST00000509690 2106 261aa ENSP00000425104
TP53-218 ENST00000604348 2488 386aa ENSP00000473895
TP53-224 ENST00000619485 2506 354aa ENSP00000482537
TP53-201 ENST00000269305 2512 393aa ENSP00000269305
TP53-217 ENST00000576024 175 31aa ENSP00000458393
TP53-216 ENST00000574684 104 No protein -
TP53-210 ENST00000505014 1261 No protein -
TP53-215 ENST00000571370 2275 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
64622Glioblastoma4E-1226424050
66549Carcinoma, Basal Cell2E-2021946351
70786Carcinoma, Basal Cell2E-1027539887
79315Carcinoma, Basal Cell1E-2025855136
88646Hormones1E-1526014426
88647Sex Hormone-Binding Globulin1E-1526014426
95054Carcinoma, Basal Cell4E-2224403052
100295Sex Hormone-Binding Globulin2E-2122829776
104807Glioma9E-2026424050

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000141510homo_sapiensENSP0000036754536.635226.4151homo_sapiensENSP0000026930559.287542.7481
ENSG00000141510homo_sapiensENSP0000026473133.529422.6471homo_sapiensENSP0000026930558.015339.1857

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000141510homo_sapiensENSP0000026930589.821988.8041nomascus_leucogenysENSNLEP0000001186197.783996.6759
ENSG00000141510homo_sapiensENSP00000269305100100pan_paniscusENSPPAP00000011040100100
ENSG00000141510homo_sapiensENSP0000026930598.218897.7099pongo_abeliiENSPPYP0000004531692.344591.866
ENSG00000141510homo_sapiensENSP00000269305100100pan_troglodytesENSPTRP00000014836100100
ENSG00000141510homo_sapiensENSP0000026930583.969583.715gorilla_gorillaENSGGOP0000003095481.885981.6377
ENSG00000141510homo_sapiensENSP0000026930570.992459.0331ornithorhynchus_anatinusENSOANP0000003761659.615449.5727
ENSG00000141510homo_sapiensENSP0000026930572.773565.1399sarcophilus_harrisiiENSSHAP0000003358168.421161.244
ENSG00000141510homo_sapiensENSP0000026930549.109445.5471notamacropus_eugeniiENSMEUP0000001197885.02278.8546
ENSG00000141510homo_sapiensENSP0000026930584.987380.4071dasypus_novemcinctusENSDNOP0000000407586.528581.8653
ENSG00000141510homo_sapiensENSP0000026930572.010263.3588erinaceus_europaeusENSEEUP0000001329575.466766.4
ENSG00000141510homo_sapiensENSP0000026930546.310441.2214echinops_telfairiENSETEP0000000811155.319149.2401
ENSG00000141510homo_sapiensENSP0000026930562.34157.7608echinops_telfairiENSETEP0000000729673.134367.7612
ENSG00000141510homo_sapiensENSP0000026930590.330886.514callithrix_jacchusENSCJAP0000006680089.646585.8586
ENSG00000141510homo_sapiensENSP0000026930593.893192.112cercocebus_atysENSCATP0000003204591.79190.0498
ENSG00000141510homo_sapiensENSP0000026930597.20195.6743macaca_fascicularisENSMFAP0000003852697.20195.6743
ENSG00000141510homo_sapiensENSP0000026930597.20195.6743macaca_mulattaENSMMUP0000001133488.221786.836
ENSG00000141510homo_sapiensENSP0000026930556.488552.6718macaca_nemestrinaENSMNEP0000003086582.222276.6667
ENSG00000141510homo_sapiensENSP0000026930596.946695.6743papio_anubisENSPANP0000001964396.946695.6743
ENSG00000141510homo_sapiensENSP0000026930593.893192.112mandrillus_leucophaeusENSMLEP0000003709991.79190.0498
ENSG00000141510homo_sapiensENSP0000026930589.567485.2417tursiops_truncatusENSTTRP0000000972190.956186.5633
ENSG00000141510homo_sapiensENSP0000026930586.259580.4071vulpes_vulpesENSVVUP0000003918788.976482.9396
ENSG00000141510homo_sapiensENSP0000026930583.206177.3537mus_spretusMGP_SPRETEiJ_P002893383.846277.9487
ENSG00000141510homo_sapiensENSP0000026930587.531883.4606equus_asinusENSEASP0000502839990.288786.0892
ENSG00000141510homo_sapiensENSP0000026930585.496279.8982capra_hircusENSCHIP0000003014187.958182.199
ENSG00000141510homo_sapiensENSP0000026930565.648958.2697loxodonta_africanaENSLAFP0000002879370.299762.3978
ENSG00000141510homo_sapiensENSP0000026930568.702362.341loxodonta_africanaENSLAFP0000002338974.175867.3077
ENSG00000141510homo_sapiensENSP0000026930568.447863.3588loxodonta_africanaENSLAFP0000002355473.29767.8474
ENSG00000141510homo_sapiensENSP0000026930565.139959.0331loxodonta_africanaENSLAFP0000002751571.111164.4444
ENSG00000141510homo_sapiensENSP0000026930565.903360.0509loxodonta_africanaENSLAFP0000002780871.944465.5556
ENSG00000141510homo_sapiensENSP0000026930564.122156.9975loxodonta_africanaENSLAFP0000002817369.041161.3699
ENSG00000141510homo_sapiensENSP0000026930582.188378.626loxodonta_africanaENSLAFP0000000629282.39878.8265
ENSG00000141510homo_sapiensENSP0000026930567.175661.3232loxodonta_africanaENSLAFP0000002585272.928266.5746
ENSG00000141510homo_sapiensENSP0000026930552.671848.0916loxodonta_africanaENSLAFP0000002744171.87565.625
ENSG00000141510homo_sapiensENSP0000026930564.63157.7608loxodonta_africanaENSLAFP0000001837969.972562.5344
ENSG00000141510homo_sapiensENSP0000026930565.648959.2875loxodonta_africanaENSLAFP0000002725370.299763.4877
ENSG00000141510homo_sapiensENSP0000026930568.193462.341loxodonta_africanaENSLAFP0000002499873.626467.3077
ENSG00000141510homo_sapiensENSP0000026930586.259580.6616panthera_leoENSPLOP0000002774387.823882.1244
ENSG00000141510homo_sapiensENSP0000026930587.531880.6616ailuropoda_melanoleucaENSAMEP0000001782572.573866.8776
ENSG00000141510homo_sapiensENSP0000026930585.750680.1527bos_indicus_hybridENSBIXP0000503964367.535163.1263
ENSG00000141510homo_sapiensENSP0000026930590.330885.7506oryctolagus_cuniculusENSOCUP0000000098990.792886.1893
ENSG00000141510homo_sapiensENSP0000026930587.786383.715equus_caballusENSECAP0000007467880.985977.23
ENSG00000141510homo_sapiensENSP0000026930586.51480.6616canis_lupus_familiarisENSCAFP0084503413889.238883.2021
ENSG00000141510homo_sapiensENSP0000026930586.259580.6616panthera_pardusENSPPRP0000002284487.823882.1244
ENSG00000141510homo_sapiensENSP0000026930591.094186.514marmota_marmota_marmotaENSMMMP0000002249191.326586.7347
ENSG00000141510homo_sapiensENSP0000026930589.31385.4962balaenoptera_musculusENSBMSP0001002070790.697786.8217
ENSG00000141510homo_sapiensENSP0000026930583.71578.1171cavia_porcellusENSCPOP0000002975177.777872.5768
ENSG00000141510homo_sapiensENSP0000026930586.005180.4071felis_catusENSFCAP0000004574965.25161.0039
ENSG00000141510homo_sapiensENSP0000026930587.022980.4071ursus_americanusENSUAMP0000000091389.763882.9396
ENSG00000141510homo_sapiensENSP0000026930586.005180.4071bison_bison_bisonENSBBBP0000001889187.564881.8653
ENSG00000141510homo_sapiensENSP0000026930589.567485.7506monodon_monocerosENSMMNP0001502198590.956187.0801
ENSG00000141510homo_sapiensENSP0000026930585.496280.4071sus_scrofaENSSSCP0000005066485.063380
ENSG00000141510homo_sapiensENSP0000026930588.295286.0051microcebus_murinusENSMICP0000003981290.129987.7922
ENSG00000141510homo_sapiensENSP0000026930583.71579.8982octodon_degusENSODEP0000002416284.793880.9278
ENSG00000141510homo_sapiensENSP0000026930584.223978.8804jaculus_jaculusENSJJAP0000000809088.978583.3333
ENSG00000141510homo_sapiensENSP0000026930585.496279.6438ovis_aries_rambouilletENSOARP0002001467987.958181.9372
ENSG00000141510homo_sapiensENSP0000026930587.022980.1527ursus_maritimusENSUMAP0000002320789.763882.6772
ENSG00000141510homo_sapiensENSP0000026930582.951775.827ochotona_princepsENSOPRP0000000590687.165879.6791
ENSG00000141510homo_sapiensENSP0000026930588.804184.7328delphinapterus_leucasENSDLEP0000002961188.131384.0909
ENSG00000141510homo_sapiensENSP0000026930590.076385.7506physeter_catodonENSPCTP0000502018691.472987.0801
ENSG00000141510homo_sapiensENSP0000026930583.71577.6081mus_caroliMGP_CAROLIEiJ_P002755484.35978.2051
ENSG00000141510homo_sapiensENSP0000026930582.951777.3537mus_musculusENSMUSP0000010429883.589777.9487
ENSG00000141510homo_sapiensENSP0000026930577.099272.0102dipodomys_ordiiENSDORP0000002366485.112479.4944
ENSG00000141510homo_sapiensENSP0000026930584.987378.626mustela_putorius_furoENSMPUP0000000894589.066782.4
ENSG00000141510homo_sapiensENSP0000026930572.773569.4657aotus_nancymaaeENSANAP0000002016577.929274.3869
ENSG00000141510homo_sapiensENSP0000026930577.608172.2646aotus_nancymaaeENSANAP0000002559290.504484.273
ENSG00000141510homo_sapiensENSP0000026930569.974666.9211aotus_nancymaaeENSANAP0000004017583.841580.1829
ENSG00000141510homo_sapiensENSP0000026930585.750683.715saimiri_boliviensis_boliviensisENSSBOP0000000818194.662992.4157
ENSG00000141510homo_sapiensENSP0000026930597.20195.9288chlorocebus_sabaeusENSCSAP0000000755197.20195.9288
ENSG00000141510homo_sapiensENSP0000026930555.216351.145tupaia_belangeriENSTBEP0000001018957.407453.1746
ENSG00000141510homo_sapiensENSP0000026930583.206176.0814mesocricetus_auratusENSMAUP0000002585282.784875.6962
ENSG00000141510homo_sapiensENSP0000026930589.31385.4962phocoena_sinusENSPSNP0000001345390.697786.8217
ENSG00000141510homo_sapiensENSP0000026930588.549683.715camelus_dromedariusENSCDRP0000501316591.338686.3517
ENSG00000141510homo_sapiensENSP0000026930591.857589.313carlito_syrichtaENSTSYP0000002375293.041290.4639
ENSG00000141510homo_sapiensENSP0000026930557.506452.4173panthera_tigris_altaicaENSPTIP0000002483475.585368.8963
ENSG00000141510homo_sapiensENSP0000026930583.969577.8626rattus_norvegicusENSRNOP0000009283181.280875.3695
ENSG00000141510homo_sapiensENSP0000026930578.117174.8092prolemur_simusENSPSMP0000002687576.942473.6842
ENSG00000141510homo_sapiensENSP0000026930583.206179.8982microtus_ochrogasterENSMOCP0000002321986.052682.6316
ENSG00000141510homo_sapiensENSP0000026930584.223978.8804sorex_araneusENSSARP0000000561685.751380.3109
ENSG00000141510homo_sapiensENSP0000026930585.750682.4427peromyscus_maniculatus_bairdiiENSPEMP0000001030086.855783.5052
ENSG00000141510homo_sapiensENSP0000026930586.005180.4071bos_mutusENSBMUP0000002886387.564881.8653
ENSG00000141510homo_sapiensENSP0000026930552.162847.0738mus_spicilegusENSMSIP0000000501778.846271.1538
ENSG00000141510homo_sapiensENSP0000026930582.951777.3537mus_spicilegusENSMSIP0000003103484.020678.3505
ENSG00000141510homo_sapiensENSP0000026930583.460676.8448cricetulus_griseus_chok1gshdENSCGRP0000101126883.460676.8448
ENSG00000141510homo_sapiensENSP0000026930563.104358.2697pteropus_vampyrusENSPVAP0000001540063.427158.5678
ENSG00000141510homo_sapiensENSP0000026930580.407173.7914myotis_lucifugusENSMLUP0000000586180.612273.9796
ENSG00000141510homo_sapiensENSP0000026930568.447862.8499myotis_lucifugusENSMLUP0000001673369.329963.6598
ENSG00000141510homo_sapiensENSP0000026930574.300366.1578vombatus_ursinusENSVURP0001000426378.918970.2703
ENSG00000141510homo_sapiensENSP0000026930586.259580.916rhinolophus_ferrumequinumENSRFEP0001001680889.210583.6842
ENSG00000141510homo_sapiensENSP0000026930585.496279.1349neovison_visonENSNVIP0000000514188.654482.058
ENSG00000141510homo_sapiensENSP0000026930585.750680.1527bos_taurusENSBTAP0000000142087.305781.6062
ENSG00000141510homo_sapiensENSP0000026930586.259582.4427heterocephalus_glaber_femaleENSHGLP0000005437686.923183.0769
ENSG00000141510homo_sapiensENSP0000026930597.455596.1832rhinopithecus_bietiENSRBIP0000002863297.455596.1832
ENSG00000141510homo_sapiensENSP0000026930586.51480.6616canis_lupus_dingoENSCAFP0002000951089.238883.2021
ENSG00000141510homo_sapiensENSP0000026930589.31386.2595sciurus_vulgarisENSSVLP000050197179086.9231
ENSG00000141510homo_sapiensENSP0000026930574.300366.6667phascolarctos_cinereusENSPCIP0000003951358.051752.0875
ENSG00000141510homo_sapiensENSP0000026930579.134974.0458procavia_capensisENSPCAP0000001189280.779275.5844
ENSG00000141510homo_sapiensENSP0000026930589.058584.4784nannospalax_galiliENSNGAP0000000730689.514184.9105
ENSG00000141510homo_sapiensENSP0000026930586.005180.4071bos_grunniensENSBGRP0000002166987.564881.8653
ENSG00000141510homo_sapiensENSP0000026930586.768482.6972chinchilla_lanigeraENSCLAP0000001040487.212383.1202
ENSG00000141510homo_sapiensENSP0000026930586.005179.6438cervus_hanglu_yarkandensisENSCHYP0000001728186.889580.4627
ENSG00000141510homo_sapiensENSP0000026930587.786383.715catagonus_wagneriENSCWAP0000000580089.378285.2332
ENSG00000141510homo_sapiensENSP0000026930590.839786.2595ictidomys_tridecemlineatusENSSTOP0000001967891.304386.7008
ENSG00000141510homo_sapiensENSP0000026930587.786383.9695otolemur_garnettiiENSOGAP0000001510687.786383.9695
ENSG00000141510homo_sapiensENSP0000026930593.384290.5852cebus_imitatorENSCCAP0000002952592.911490.1266
ENSG00000141510homo_sapiensENSP0000026930590.839786.0051urocitellus_parryiiENSUPAP0001001948590.609185.7868
ENSG00000141510homo_sapiensENSP0000026930586.768481.4249moschus_moschiferusENSMMSP0000002657888.113782.6873
ENSG00000141510homo_sapiensENSP0000026930597.455596.1832rhinopithecus_roxellanaENSRROP0000002684397.455596.1832
ENSG00000141510homo_sapiensENSP0000026930583.460676.5903mus_pahariMGP_PahariEiJ_P003430678.846272.3558
ENSG00000141510homo_sapiensENSP0000026930591.348688.5496propithecus_coquereliENSPCOP0000003175893.246790.3896
ENSG00000141510homo_sapiensENSP0000026930538.676822.1374drosophila_melanogasterFBpp008375330.707117.5758
ENSG00000141510homo_sapiensENSP0000026930548.85532.0611ciona_intestinalisENSCINP0000000395639.263825.7669
ENSG00000141510homo_sapiensENSP0000026930544.529329.771ciona_intestinalisENSCINP0000000444741.766127.9236
ENSG00000141510homo_sapiensENSP0000026930518.06628.90585eptatretus_burgeriENSEBUP0000001723738.797819.1257
ENSG00000141510homo_sapiensENSP0000026930562.849949.3639latimeria_chalumnaeENSLACP0000001591561.59648.3791
ENSG00000141510homo_sapiensENSP0000026930561.577648.0916lepisosteus_oculatusENSLOCP0000001706361.265847.8481
ENSG00000141510homo_sapiensENSP0000026930554.452943.257clupea_harengusENSCHAP0000003940857.994646.0705
ENSG00000141510homo_sapiensENSP0000026930541.475832.3155clupea_harengusENSCHAP0000003935751.74640.3175
ENSG00000141510homo_sapiensENSP0000026930555.725243.0025clupea_harengusENSCHAP0000004214355.30342.6768
ENSG00000141510homo_sapiensENSP0000026930558.778647.5827danio_rerioENSDARP0000011673662.601650.6775
ENSG00000141510homo_sapiensENSP0000026930554.961844.2748carassius_auratusENSCARP0000008678560.674248.8764
ENSG00000141510homo_sapiensENSP0000026930556.488545.5471carassius_auratusENSCARP0000013138257.216546.134
ENSG00000141510homo_sapiensENSP0000026930556.997543.257astyanax_mexicanusENSAMXP0000003502556.852843.1472
ENSG00000141510homo_sapiensENSP0000026930553.435143.0025astyanax_mexicanusENSAMXP0000002136658.988847.4719
ENSG00000141510homo_sapiensENSP0000026930559.796447.8372ictalurus_punctatusENSIPUP0000003191962.550
ENSG00000141510homo_sapiensENSP0000026930556.234142.7481ictalurus_punctatusENSIPUP0000002896756.091442.6396
ENSG00000141510homo_sapiensENSP0000026930558.524243.7659esox_luciusENSELUP0000001431958.974444.1026
ENSG00000141510homo_sapiensENSP0000026930561.068749.3639esox_luciusENSELUP0000006055553.571443.3036
ENSG00000141510homo_sapiensENSP0000026930552.417337.4046electrophorus_electricusENSEEEP0000004266756.284240.1639
ENSG00000141510homo_sapiensENSP0000026930559.54247.3282electrophorus_electricusENSEEEP0000003398263.243250.2703
ENSG00000141510homo_sapiensENSP0000026930561.323248.855oncorhynchus_kisutchENSOKIP0000509968160.858648.4848
ENSG00000141510homo_sapiensENSP0000026930557.760843.7659oncorhynchus_kisutchENSOKIP0000506694357.908243.8776
ENSG00000141510homo_sapiensENSP0000026930558.778644.0204oncorhynchus_kisutchENSOKIP0000502372458.186443.5768
ENSG00000141510homo_sapiensENSP0000026930557.760843.7659oncorhynchus_mykissENSOMYP0000006778557.035243.2161
ENSG00000141510homo_sapiensENSP0000026930559.033144.2748oncorhynchus_mykissENSOMYP0000006774956.310742.233
ENSG00000141510homo_sapiensENSP0000026930559.54247.3282oncorhynchus_mykissENSOMYP0000005172957.212745.4768
ENSG00000141510homo_sapiensENSP0000026930561.068748.3461salmo_salarENSSSAP0000005795861.696748.8432
ENSG00000141510homo_sapiensENSP0000026930558.015344.0204salmo_salarENSSSAP0000016106758.163344.1327
ENSG00000141510homo_sapiensENSP0000026930558.015343.7659salmo_truttaENSSTUP0000010639258.163343.8776
ENSG00000141510homo_sapiensENSP0000026930558.269743.5115salmo_truttaENSSTUP0000007057657.2542.75
ENSG00000141510homo_sapiensENSP0000026930561.577648.6005salmo_truttaENSSTUP0000010130961.111148.2323
ENSG00000141510homo_sapiensENSP0000026930552.671839.9491gadus_morhuaENSGMOP0000004887747.260335.8447
ENSG00000141510homo_sapiensENSP0000026930552.162840.9669fundulus_heteroclitusENSFHEP0000000106358.238645.7386
ENSG00000141510homo_sapiensENSP0000026930551.399540.7125poecilia_reticulataENSPREP0000001967659.064346.7836
ENSG00000141510homo_sapiensENSP0000026930533.842223.4097xiphophorus_maculatusENSXMAP0000002689438.888926.9006
ENSG00000141510homo_sapiensENSP0000026930552.417341.7303xiphophorus_maculatusENSXMAP0000002882960.233947.9532
ENSG00000141510homo_sapiensENSP0000026930550.636138.6768oryzias_latipesENSORLP0000000803156.534143.1818
ENSG00000141510homo_sapiensENSP0000026930555.216342.4936cyclopterus_lumpusENSCLMP0000503089956.363643.3766
ENSG00000141510homo_sapiensENSP0000026930554.198540.9669oreochromis_niloticusENSONIP0000004180956.842.9333
ENSG00000141510homo_sapiensENSP0000026930557.251943.5115haplochromis_burtoniENSHBUP0000002221357.544843.734
ENSG00000141510homo_sapiensENSP0000026930555.470741.9847astatotilapia_callipteraENSACLP0000000704056.770842.9688
ENSG00000141510homo_sapiensENSP0000026930555.979643.0025sparus_aurataENSSAUP0001002987958.047544.591
ENSG00000141510homo_sapiensENSP0000026930556.488542.4936lates_calcariferENSLCAP0001001605258.421143.9474
ENSG00000141510homo_sapiensENSP0000026930556.997546.5649xenopus_tropicalisENSXETP0000005375961.878550.5525
ENSG00000141510homo_sapiensENSP0000026930558.269747.8372chrysemys_picta_belliiENSCPBP0000003158256.823846.6501
ENSG00000141510homo_sapiensENSP0000026930551.653940.7125sphenodon_punctatusENSSPUP0000001884264.037950.4732
ENSG00000141510homo_sapiensENSP0000026930549.618339.4402laticauda_laticaudataENSLLTP0000002410547.101437.4396
ENSG00000141510homo_sapiensENSP0000026930546.819336.8957notechis_scutatusENSNSUP0000000332848.041837.859
ENSG00000141510homo_sapiensENSP0000026930525.190821.374pseudonaja_textilisENSPTXP0000002066066.44356.3758
ENSG00000141510homo_sapiensENSP0000026930534.096729.2621gallus_gallusENSGALP0001000046768.717958.9744
ENSG00000141510homo_sapiensENSP0000026930523.409717.5573anolis_carolinensisENSACAP0000002119660.526345.3947
ENSG00000141510homo_sapiensENSP0000026930546.819335.1145neolamprologus_brichardiENSNBRP0000002685551.540638.6555
ENSG00000141510homo_sapiensENSP0000026930524.17320.3562naja_najaENSNNAP0000001325561.688351.9481
ENSG00000141510homo_sapiensENSP0000026930555.216341.4758podarcis_muralisENSPMRP0000001781155.216341.4758
ENSG00000141510homo_sapiensENSP0000026930546.310438.6768taeniopygia_guttataENSTGUP0000002151954.654745.6456
ENSG00000141510homo_sapiensENSP0000026930546.05636.1323taeniopygia_guttataENSTGUP0000003265542.89133.6493
ENSG00000141510homo_sapiensENSP0000026930561.323248.3461erpetoichthys_calabaricusENSECRP0000001571357.932745.6731
ENSG00000141510homo_sapiensENSP0000026930553.435142.4936kryptolebias_marmoratusENSKMAP0000001896956.451644.8925
ENSG00000141510homo_sapiensENSP0000026930556.234145.2926salvator_merianaeENSSMRP0000000387156.234145.2926
ENSG00000141510homo_sapiensENSP0000026930552.926240.7125oryzias_javanicusENSOJAP0000003126659.770145.977
ENSG00000141510homo_sapiensENSP0000026930553.689640.9669amphilophus_citrinellusENSACIP0000002037359.943245.7386
ENSG00000141510homo_sapiensENSP0000026930553.94441.4758dicentrarchus_labraxENSDLAP0000501826158.888945.2778
ENSG00000141510homo_sapiensENSP0000026930555.725241.7303amphiprion_perculaENSAPEP0000001792758.443.7333
ENSG00000141510homo_sapiensENSP0000026930551.653939.1857oryzias_sinensisENSOSIP0000000146657.183143.3803
ENSG00000141510homo_sapiensENSP0000026930557.760847.5827pelodiscus_sinensisENSPSIP0000001490558.205147.9487
ENSG00000141510homo_sapiensENSP0000026930557.506446.5649gopherus_evgoodeiENSGEVP0000502011155.528344.9631
ENSG00000141510homo_sapiensENSP0000026930557.251946.5649chelonoidis_abingdoniiENSCABP0000001827455.282644.9631
ENSG00000141510homo_sapiensENSP0000026930557.251942.2392seriola_dumeriliENSSDUP0000002822659.681744.0318
ENSG00000141510homo_sapiensENSP0000026930555.470742.7481cottoperca_gobioENSCGOP0000001443058.44545.0402
ENSG00000141510homo_sapiensENSP0000026930554.198539.9491gasterosteus_aculeatusENSGACP0000002561458.196742.8962
ENSG00000141510homo_sapiensENSP0000026930553.435140.2036cynoglossus_semilaevisENSCSEP0000000399755.702941.9098
ENSG00000141510homo_sapiensENSP0000026930551.908441.2214poecilia_formosaENSPFOP0000000755659.649147.3684
ENSG00000141510homo_sapiensENSP0000026930557.251941.9847myripristis_murdjanENSMMDP0000505128959.681743.7666
ENSG00000141510homo_sapiensENSP0000026930556.234142.7481sander_luciopercaENSSLUP0000003902755.949442.5316
ENSG00000141510homo_sapiensENSP0000026930550.890640.2036strigops_habroptilaENSSHBP0000500754461.728448.7654
ENSG00000141510homo_sapiensENSP0000026930555.725241.7303amphiprion_ocellarisENSAOCP0000000138558.443.7333
ENSG00000141510homo_sapiensENSP0000026930559.033148.855terrapene_carolina_triunguisENSTMTP0000002837857.568247.6427
ENSG00000141510homo_sapiensENSP0000026930561.832149.3639hucho_huchoENSHHUP0000001346856.511645.1163
ENSG00000141510homo_sapiensENSP0000026930558.778644.0204hucho_huchoENSHHUP0000006155059.689944.7028
ENSG00000141510homo_sapiensENSP0000026930558.015343.5115hucho_huchoENSHHUP0000007294158.762944.0722
ENSG00000141510homo_sapiensENSP0000026930536.641228.2443betta_splendensENSBSLP0000004584464.864950
ENSG00000141510homo_sapiensENSP0000026930526.717622.6463betta_splendensENSBSLP0000003436762.874353.2934
ENSG00000141510homo_sapiensENSP0000026930536.895728.2443betta_splendensENSBSLP0000003577633.180825.4005
ENSG00000141510homo_sapiensENSP0000026930533.078926.4631betta_splendensENSBSLP0000004820547.272737.8182
ENSG00000141510homo_sapiensENSP0000026930535.114526.972betta_splendensENSBSLP0000002314730.598723.5033
ENSG00000141510homo_sapiensENSP0000026930534.860127.4809betta_splendensENSBSLP0000004840552.895841.6988
ENSG00000141510homo_sapiensENSP0000026930525.699720.8651betta_splendensENSBSLP0000002407574.264760.2941
ENSG00000141510homo_sapiensENSP0000026930537.150128.4987betta_splendensENSBSLP0000002380765.470950.2242
ENSG00000141510homo_sapiensENSP0000026930535.623427.4809betta_splendensENSBSLP0000005232531.042123.9468
ENSG00000141510homo_sapiensENSP0000026930526.717622.6463betta_splendensENSBSLP0000001075962.874353.2934
ENSG00000141510homo_sapiensENSP0000026930536.132327.9898betta_splendensENSBSLP0000001086431.485624.3902
ENSG00000141510homo_sapiensENSP0000026930527.226521.6285betta_splendensENSBSLP0000002374655.729244.2708
ENSG00000141510homo_sapiensENSP0000026930537.150128.4987betta_splendensENSBSLP0000000475165.470950.2242
ENSG00000141510homo_sapiensENSP0000026930533.587825.6997betta_splendensENSBSLP0000003636765.671650.2488
ENSG00000141510homo_sapiensENSP0000026930531.552225.1908betta_splendensENSBSLP0000001330247.692338.0769
ENSG00000141510homo_sapiensENSP0000026930537.150128.7532betta_splendensENSBSLP0000003100966.666751.5982
ENSG00000141510homo_sapiensENSP0000026930527.989823.1552betta_splendensENSBSLP0000003549463.218452.2989
ENSG00000141510homo_sapiensENSP0000026930534.860126.972betta_splendensENSBSLP0000002079263.425949.0741
ENSG00000141510homo_sapiensENSP0000026930533.587824.173betta_splendensENSBSLP0000002352854.32139.0947
ENSG00000141510homo_sapiensENSP0000026930537.65928.2443betta_splendensENSBSLP0000000463536.363627.2727
ENSG00000141510homo_sapiensENSP0000026930534.860126.2087betta_splendensENSBSLP0000000501955.691141.8699
ENSG00000141510homo_sapiensENSP0000026930545.801534.3511betta_splendensENSBSLP0000001653053.571440.1786
ENSG00000141510homo_sapiensENSP0000026930539.694730.7888betta_splendensENSBSLP0000003224553.793141.7241
ENSG00000141510homo_sapiensENSP0000026930528.753223.1552betta_splendensENSBSLP0000005324558.854247.3958
ENSG00000141510homo_sapiensENSP0000026930550.381738.9313betta_splendensENSBSLP0000001904955.153242.6184
ENSG00000141510homo_sapiensENSP0000026930556.997544.2748pygocentrus_nattereriENSPNAP0000001450155.721443.2836
ENSG00000141510homo_sapiensENSP0000026930556.234141.4758pygocentrus_nattereriENSPNAP0000003057956.812341.9023
ENSG00000141510homo_sapiensENSP0000026930555.979642.7481anabas_testudineusENSATEP0000002832857.742844.0945
ENSG00000141510homo_sapiensENSP0000026930547.837230.7888ciona_savignyiENSCSAVP0000001694039.085225.1559
ENSG00000141510homo_sapiensENSP0000026930541.475827.9898ciona_savignyiENSCSAVP0000001665941.057927.7078
ENSG00000141510homo_sapiensENSP0000026930556.997542.2392seriola_lalandi_dorsalisENSSLDP0000001320959.416444.0318
ENSG00000141510homo_sapiensENSP0000026930555.216343.0025labrus_bergyltaENSLBEP0000003685758.021445.1872
ENSG00000141510homo_sapiensENSP0000026930547.328233.8422pundamilia_nyerereiENSPNYP0000000881652.100837.2549
ENSG00000141510homo_sapiensENSP0000026930555.470742.2392mastacembelus_armatusENSMAMP0000000531557.217843.5696
ENSG00000141510homo_sapiensENSP0000026930555.470741.9847stegastes_partitusENSSPAP0000002201957.217843.3071
ENSG00000141510homo_sapiensENSP0000026930561.577648.855oncorhynchus_tshawytschaENSOTSP0000502792553.30442.2907
ENSG00000141510homo_sapiensENSP0000026930559.287544.7837oncorhynchus_tshawytschaENSOTSP0000510509458.690244.3325
ENSG00000141510homo_sapiensENSP0000026930558.269743.5115oncorhynchus_tshawytschaENSOTSP0000501382453.6340.0468
ENSG00000141510homo_sapiensENSP0000026930555.725241.9847acanthochromis_polyacanthusENSAPOP0000002771558.713144.2359
ENSG00000141510homo_sapiensENSP0000026930529.516525.6997aquila_chrysaetos_chrysaetosENSACCP0002002461055.238148.0952
ENSG00000141510homo_sapiensENSP0000026930550.636137.9135nothobranchius_furzeriENSNFUP0001500372053.494640.0538
ENSG00000141510homo_sapiensENSP0000026930550.381739.9491cyprinodon_variegatusENSCVAP0000002239856.410344.7293
ENSG00000141510homo_sapiensENSP0000026930551.399539.1857denticeps_clupeoidesENSDCDP0000003311054.155541.2869
ENSG00000141510homo_sapiensENSP0000026930558.524248.0916denticeps_clupeoidesENSDCDP0000000701759.740349.0909
ENSG00000141510homo_sapiensENSP0000026930554.961842.4936larimichthys_croceaENSLCRP0000501197660.335246.648
ENSG00000141510homo_sapiensENSP0000026930553.180741.7303takifugu_rubripesENSTRUP0000003064453.452741.9437
ENSG00000141510homo_sapiensENSP0000026930553.180738.6768hippocampus_comesENSHCOP0000002297055.585140.4255
ENSG00000141510homo_sapiensENSP0000026930554.452940.9669cyprinus_carpio_carpioENSCCRP0000006226857.219243.0481
ENSG00000141510homo_sapiensENSP0000026930558.524246.3104cyprinus_carpio_carpioENSCCRP0000000198053.738342.5234
ENSG00000141510homo_sapiensENSP0000026930559.796447.5827cyprinus_carpio_carpioENSCCRP0000014017561.197948.6979
ENSG00000141510homo_sapiensENSP0000026930551.653940.9669poecilia_latipinnaENSPLAP0000002269459.356747.076
ENSG00000141510homo_sapiensENSP0000026930560.559847.3282sinocyclocheilus_grahamiENSSGRP0000007418361.498748.062
ENSG00000141510homo_sapiensENSP0000026930559.54248.0916sinocyclocheilus_grahamiENSSGRP0000005952061.417349.6063
ENSG00000141510homo_sapiensENSP0000026930548.85537.9135maylandia_zebraENSMZEP0000502909753.481941.5042
ENSG00000141510homo_sapiensENSP0000026930553.689640.9669tetraodon_nigroviridisENSTNIP0000001303557.96744.2308
ENSG00000141510homo_sapiensENSP0000026930558.778649.1094paramormyrops_kingsleyaeENSPKIP0000001480553.596344.7796
ENSG00000141510homo_sapiensENSP0000026930553.180741.2214paramormyrops_kingsleyaeENSPKIP0000002102247.392336.7347
ENSG00000141510homo_sapiensENSP0000026930554.198540.2036scleropages_formosusENSSFOP0001500008053.2539.5
ENSG00000141510homo_sapiensENSP0000026930562.086549.6183scleropages_formosusENSSFOP0001503579552.813942.2078
ENSG00000141510homo_sapiensENSP0000026930554.452944.2748leptobrachium_leishanenseENSLLEP0000003802556.763946.1538
ENSG00000141510homo_sapiensENSP0000026930556.997543.257scophthalmus_maximusENSSMAP0000001506458.792744.6194
ENSG00000141510homo_sapiensENSP0000026930552.162840.458oryzias_melastigmaENSOMEP0000000930959.248645.9538

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II2IDA,ISSHomo_sapiens(9606)Process
GO:0000423involved_in mitophagy1IEAHomo_sapiens(9606)Process
GO:0000785part_of chromatin3IDA,IMP,ISAHomo_sapiens(9606)Component
GO:0000976enables transcription cis-regulatory region binding1IDAHomo_sapiens(9606)Function
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding3IBA,IDA,ISSHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific3IBA,IDA,ISAHomo_sapiens(9606)Function
GO:0000987enables cis-regulatory region sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0001046enables core promoter sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0001094enables TFIID-class transcription factor complex binding1IPIHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific1IDAHomo_sapiens(9606)Function
GO:0001228enables DNA-binding transcription activator activity, RNA polymerase II-specific1IDAHomo_sapiens(9606)Function
GO:0001701involved_in in utero embryonic development1IEAHomo_sapiens(9606)Process
GO:0001756involved_in somitogenesis1IEAHomo_sapiens(9606)Process
GO:0001836involved_in release of cytochrome c from mitochondria1IEAHomo_sapiens(9606)Process
GO:0002020enables protease binding1IPIHomo_sapiens(9606)Function
GO:0002039enables p53 binding1IPIHomo_sapiens(9606)Function
GO:0002244involved_in hematopoietic progenitor cell differentiation1IMPHomo_sapiens(9606)Process
GO:0002309involved_in T cell proliferation involved in immune response1IEAHomo_sapiens(9606)Process
GO:0002326involved_in B cell lineage commitment1IEAHomo_sapiens(9606)Process
GO:0002360involved_in T cell lineage commitment1IEAHomo_sapiens(9606)Process
GO:0002931involved_in response to ischemia1IEAHomo_sapiens(9606)Process
GO:0003677enables DNA binding2IDA,IMPHomo_sapiens(9606)Function
GO:0003682enables chromatin binding1IDAHomo_sapiens(9606)Function
GO:0003700enables DNA-binding transcription factor activity2IDA,IMPHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding1IDAHomo_sapiens(9606)Function
GO:0005507enables copper ion binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus2IDA,IMPHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005657located_in replication fork1IEAHomo_sapiens(9606)Component
GO:0005667part_of transcription regulator complex1IGIHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm2IDA,IMPHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix1IEAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IEAHomo_sapiens(9606)Component
GO:0005813located_in centrosome1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006289involved_in nucleotide-excision repair1IMPHomo_sapiens(9606)Process
GO:0006302involved_in double-strand break repair1IEAHomo_sapiens(9606)Process
GO:0006355involved_in regulation of DNA-templated transcription2IDA,IMPHomo_sapiens(9606)Process
GO:0006357involved_in regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0006606involved_in protein import into nucleus1IEAHomo_sapiens(9606)Process
GO:0006914involved_in autophagy1IMPHomo_sapiens(9606)Process
GO:0006974acts_upstream_of_or_within DNA damage response3IDA,IMPHomo_sapiens(9606)Process
GO:0006977involved_in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1IMPHomo_sapiens(9606)Process
GO:0006978involved_in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator2IDA,IMPHomo_sapiens(9606)Process
GO:0006983acts_upstream_of_or_within ER overload response1IDAHomo_sapiens(9606)Process
GO:0007179involved_in transforming growth factor beta receptor signaling pathway1IEAHomo_sapiens(9606)Process
GO:0007265involved_in Ras protein signal transduction1IEPHomo_sapiens(9606)Process
GO:0007369involved_in gastrulation1IEAHomo_sapiens(9606)Process
GO:0007405involved_in neuroblast proliferation1IEAHomo_sapiens(9606)Process
GO:0007406involved_in negative regulation of neuroblast proliferation1IEAHomo_sapiens(9606)Process
GO:0008104involved_in protein localization1IDAHomo_sapiens(9606)Process
GO:0008156involved_in negative regulation of DNA replication1IEAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1TASHomo_sapiens(9606)Function
GO:0008285involved_in negative regulation of cell population proliferation4IDA,IMP,ISSHomo_sapiens(9606)Process
GO:0008340involved_in determination of adult lifespan1ISSHomo_sapiens(9606)Process
GO:0009299involved_in mRNA transcription1IMPHomo_sapiens(9606)Process
GO:0009303involved_in rRNA transcription1IEAHomo_sapiens(9606)Process
GO:0009651involved_in response to salt stress1IEAHomo_sapiens(9606)Process
GO:0010035involved_in response to inorganic substance1IEAHomo_sapiens(9606)Process
GO:0010165involved_in response to X-ray1IEAHomo_sapiens(9606)Process
GO:0010332involved_in response to gamma radiation1IMPHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression4IDA,IMP,ISSHomo_sapiens(9606)Process
GO:0010659involved_in cardiac muscle cell apoptotic process1IEAHomo_sapiens(9606)Process
GO:0010666involved_in positive regulation of cardiac muscle cell apoptotic process1IEAHomo_sapiens(9606)Process
GO:0014009involved_in glial cell proliferation1IEAHomo_sapiens(9606)Process
GO:0016032involved_in viral process1IMPHomo_sapiens(9606)Process
GO:0016363located_in nuclear matrix1IDAHomo_sapiens(9606)Component
GO:0016604colocalizes_with nuclear body1IDAHomo_sapiens(9606)Component
GO:0016605located_in PML body1IDAHomo_sapiens(9606)Component
GO:0017053part_of transcription repressor complex1IPIHomo_sapiens(9606)Component
GO:0019661involved_in glucose catabolic process to lactate via pyruvate1IEAHomo_sapiens(9606)Process
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0021549involved_in cerebellum development1IEAHomo_sapiens(9606)Process
GO:0030308involved_in negative regulation of cell growth1IMPHomo_sapiens(9606)Process
GO:0030330involved_in DNA damage response, signal transduction by p53 class mediator2IDA,IMPHomo_sapiens(9606)Process
GO:0030512involved_in negative regulation of transforming growth factor beta receptor signaling pathway1IEAHomo_sapiens(9606)Process
GO:0030971enables receptor tyrosine kinase binding1IPIHomo_sapiens(9606)Function
GO:0031571involved_in mitotic G1 DNA damage checkpoint signaling1IMPHomo_sapiens(9606)Process
GO:0031625enables ubiquitin protein ligase binding2EXP,IPIHomo_sapiens(9606)Function
GO:0032991part_of protein-containing complex2IDA,IMPHomo_sapiens(9606)Component
GO:0033077involved_in T cell differentiation in thymus1IEAHomo_sapiens(9606)Process
GO:0033209involved_in tumor necrosis factor-mediated signaling pathway1IGIHomo_sapiens(9606)Process
GO:0034103involved_in regulation of tissue remodeling1IEAHomo_sapiens(9606)Process
GO:0034644involved_in cellular response to UV1IDAHomo_sapiens(9606)Process
GO:0035033enables histone deacetylase regulator activity1IEAHomo_sapiens(9606)Function
GO:0035264involved_in multicellular organism growth1IEAHomo_sapiens(9606)Process
GO:0035794involved_in positive regulation of mitochondrial membrane permeability1IEAHomo_sapiens(9606)Process
GO:0035861located_in site of double-strand break1IEAHomo_sapiens(9606)Component
GO:0036003involved_in positive regulation of transcription from RNA polymerase II promoter in response to stress1IDAHomo_sapiens(9606)Process
GO:0036310enables ATP-dependent DNA/DNA annealing activity1IDAHomo_sapiens(9606)Function
GO:0042149acts_upstream_of_or_within cellular response to glucose starvation2IDAHomo_sapiens(9606)Process
GO:0042771acts_upstream_of_or_within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator3IDA,IMPHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0042826enables histone deacetylase binding1IPIHomo_sapiens(9606)Function
GO:0042981acts_upstream_of_or_within regulation of apoptotic process1IDAHomo_sapiens(9606)Process
GO:0043065involved_in positive regulation of apoptotic process1IDAHomo_sapiens(9606)Process
GO:0043066involved_in negative regulation of apoptotic process2IGI,IMPHomo_sapiens(9606)Process
GO:0043073located_in germ cell nucleus1IEAHomo_sapiens(9606)Component
GO:0043153involved_in entrainment of circadian clock by photoperiod1ISSHomo_sapiens(9606)Process
GO:0043504involved_in mitochondrial DNA repair1IEAHomo_sapiens(9606)Process
GO:0043516involved_in regulation of DNA damage response, signal transduction by p53 class mediator1IEAHomo_sapiens(9606)Process
GO:0043525involved_in positive regulation of neuron apoptotic process1IEAHomo_sapiens(9606)Process
GO:0043621enables protein self-association1IPIHomo_sapiens(9606)Function
GO:0045815involved_in transcription initiation-coupled chromatin remodeling1IDAHomo_sapiens(9606)Process
GO:0045861involved_in negative regulation of proteolysis1IEAHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription3IDA,IMP,NASHomo_sapiens(9606)Process
GO:0045893involved_in positive regulation of DNA-templated transcription2IDA,IMPHomo_sapiens(9606)Process
GO:0045899involved_in positive regulation of RNA polymerase II transcription preinitiation complex assembly1IDAHomo_sapiens(9606)Process
GO:0045944acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II4IDA,IGI,IMPHomo_sapiens(9606)Process
GO:0046677involved_in response to antibiotic1IEPHomo_sapiens(9606)Process
GO:0046982enables protein heterodimerization activity1IPIHomo_sapiens(9606)Function
GO:0048144involved_in fibroblast proliferation1IEAHomo_sapiens(9606)Process
GO:0048147involved_in negative regulation of fibroblast proliferation1IMPHomo_sapiens(9606)Process
GO:0048512involved_in circadian behavior1ISSHomo_sapiens(9606)Process
GO:0048539involved_in bone marrow development1IMPHomo_sapiens(9606)Process
GO:0048568involved_in embryonic organ development1IEAHomo_sapiens(9606)Process
GO:0050731involved_in positive regulation of peptidyl-tyrosine phosphorylation1ISSHomo_sapiens(9606)Process
GO:0050821involved_in protein stabilization1IEAHomo_sapiens(9606)Process
GO:0051087enables protein-folding chaperone binding1IPIHomo_sapiens(9606)Function
GO:0051097involved_in negative regulation of helicase activity1TASHomo_sapiens(9606)Process
GO:0051262involved_in protein tetramerization1IEAHomo_sapiens(9606)Process
GO:0051276involved_in chromosome organization1IEAHomo_sapiens(9606)Process
GO:0051402involved_in neuron apoptotic process1IEAHomo_sapiens(9606)Process
GO:0051721enables protein phosphatase 2A binding1IPIHomo_sapiens(9606)Function
GO:0051726involved_in regulation of cell cycle4IDA,IGI,IMP,ISSHomo_sapiens(9606)Process
GO:0051974involved_in negative regulation of telomerase activity1IDAHomo_sapiens(9606)Process
GO:0060218involved_in hematopoietic stem cell differentiation1IMPHomo_sapiens(9606)Process
GO:0060253involved_in negative regulation of glial cell proliferation1IEAHomo_sapiens(9606)Process
GO:0060333involved_in type II interferon-mediated signaling pathway1IEAHomo_sapiens(9606)Process
GO:0060411involved_in cardiac septum morphogenesis1IEAHomo_sapiens(9606)Process
GO:0061419involved_in positive regulation of transcription from RNA polymerase II promoter in response to hypoxia1IEAHomo_sapiens(9606)Process
GO:0061629enables RNA polymerase II-specific DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:0062100involved_in positive regulation of programmed necrotic cell death1IEAHomo_sapiens(9606)Process
GO:0065003involved_in protein-containing complex assembly1IDAHomo_sapiens(9606)Process
GO:0070059involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress1IEAHomo_sapiens(9606)Process
GO:0070242involved_in thymocyte apoptotic process1IEAHomo_sapiens(9606)Process
GO:0070245involved_in positive regulation of thymocyte apoptotic process1ISSHomo_sapiens(9606)Process
GO:0070266involved_in necroptotic process1IEAHomo_sapiens(9606)Process
GO:0071456involved_in cellular response to hypoxia1IEPHomo_sapiens(9606)Process
GO:0071466involved_in cellular response to xenobiotic stimulus1IEPHomo_sapiens(9606)Process
GO:0071479involved_in cellular response to ionizing radiation1IMPHomo_sapiens(9606)Process
GO:0071480involved_in cellular response to gamma radiation1IDAHomo_sapiens(9606)Process
GO:0071494involved_in cellular response to UV-C1IEAHomo_sapiens(9606)Process
GO:0071889enables 14-3-3 protein binding1EXPHomo_sapiens(9606)Function
GO:0072089involved_in stem cell proliferation1IEAHomo_sapiens(9606)Process
GO:0072331involved_in signal transduction by p53 class mediator1IDAHomo_sapiens(9606)Process
GO:0072332involved_in intrinsic apoptotic signaling pathway by p53 class mediator1IMPHomo_sapiens(9606)Process
GO:0072593involved_in reactive oxygen species metabolic process1IEAHomo_sapiens(9606)Process
GO:0072717involved_in cellular response to actinomycin D1IDAHomo_sapiens(9606)Process
GO:0090200involved_in positive regulation of release of cytochrome c from mitochondria1IDAHomo_sapiens(9606)Process
GO:0090398involved_in cellular senescence1IMPHomo_sapiens(9606)Process
GO:0090399involved_in replicative senescence1IMPHomo_sapiens(9606)Process
GO:0090403involved_in oxidative stress-induced premature senescence1IMPHomo_sapiens(9606)Process
GO:0097193involved_in intrinsic apoptotic signaling pathway1TASHomo_sapiens(9606)Process
GO:0097252involved_in oligodendrocyte apoptotic process1IDAHomo_sapiens(9606)Process
GO:0097371enables MDM2/MDM4 family protein binding1IEAHomo_sapiens(9606)Function
GO:0097718enables disordered domain specific binding1IPIHomo_sapiens(9606)Function
GO:0140296enables general transcription initiation factor binding1IPIHomo_sapiens(9606)Function
GO:0140677enables molecular function activator activity2EXP,IPIHomo_sapiens(9606)Function
GO:1900119involved_in positive regulation of execution phase of apoptosis1IMPHomo_sapiens(9606)Process
GO:1901525involved_in negative regulation of mitophagy1IEAHomo_sapiens(9606)Process
GO:1902108involved_in regulation of mitochondrial membrane permeability involved in apoptotic process1IEAHomo_sapiens(9606)Process
GO:1902253involved_in regulation of intrinsic apoptotic signaling pathway by p53 class mediator1IEAHomo_sapiens(9606)Process
GO:1902749acts_upstream_of_negative_effect regulation of cell cycle G2/M phase transition1IMPHomo_sapiens(9606)Process
GO:1902895involved_in positive regulation of miRNA transcription3IDA,IGI,IMPHomo_sapiens(9606)Process
GO:1903451involved_in negative regulation of G1 to G0 transition2IDA,IMPHomo_sapiens(9606)Process
GO:1903799involved_in negative regulation of miRNA processing1IEAHomo_sapiens(9606)Process
GO:1904024involved_in negative regulation of glucose catabolic process to lactate via pyruvate1IEAHomo_sapiens(9606)Process
GO:1905856involved_in negative regulation of pentose-phosphate shunt1IMPHomo_sapiens(9606)Process
GO:1990144involved_in intrinsic apoptotic signaling pathway in response to hypoxia1IEAHomo_sapiens(9606)Process
GO:1990440involved_in positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress1ISSHomo_sapiens(9606)Process
GO:1990841enables promoter-specific chromatin binding1IDAHomo_sapiens(9606)Function
GO:2000269involved_in regulation of fibroblast apoptotic process1IEAHomo_sapiens(9606)Process
GO:2000378involved_in negative regulation of reactive oxygen species metabolic process1IEAHomo_sapiens(9606)Process
GO:2000379involved_in positive regulation of reactive oxygen species metabolic process1IMPHomo_sapiens(9606)Process
GO:2000647involved_in negative regulation of stem cell proliferation1IEAHomo_sapiens(9606)Process
GO:2000774involved_in positive regulation of cellular senescence2IDA,ISSHomo_sapiens(9606)Process
GO:2001244involved_in positive regulation of intrinsic apoptotic signaling pathway2IMP,ISSHomo_sapiens(9606)Process

Expression